Read in Data

read_csv("../output/rev_coral_join.csv") -> rev_coral_join
## Rows: 778 Columns: 5897
## ── Column specification ────────────────────────────────────────────────────────
## Delimiter: ","
## chr    (6): Clade, Majority, sample_id, species, region, reef
## dbl (5891): ITS2_type, its2_count, ASV0001, ASV0002, ASV0003, ASV0004, ASV00...
## 
## ℹ Use `spec()` to retrieve the full column specification for this data.
## ℹ Specify the column types or set `show_col_types = FALSE` to quiet this message.

Clade C and Non-Clade C Label Subsetting

# Assuming 'df' is your data frame with a column 'labels' and you want to balance the labels

# Extract the minority class samples (139 observations)
minority_class <- rev_coral_join[rev_coral_join$Clade == 'C', ]

# Extract the majority class samples (the rest of the dataset)
majority_class <- rev_coral_join[rev_coral_join$Clade != 'C', ]

# Randomly sample from the majority class to match the size of the minority class
set.seed(42)  # Set a seed for reproducibility
balanced_majority <- majority_class[sample(nrow(majority_class), nrow(minority_class)), ]

# Combine the balanced datasets
balanced_df <- rbind(balanced_majority, minority_class)

# Shuffle the rows to randomize the order
balanced_df <- balanced_df[sample(nrow(balanced_df)), ]
dim(balanced_df)
## [1]  278 5897
unique(balanced_df$Clade)
## [1] "C" "A" "G" "D"
length(balanced_df$Clade=="C")
## [1] 278
length(balanced_df$Clade != "C")
## [1] 278

Read in results from PCA Clade C Dim 1 Results

read_csv("../output/clade_c_pca_Ranks.csv") -> clade_c_pca_Ranks
## Rows: 3226 Columns: 1
## ── Column specification ────────────────────────────────────────────────────────
## Delimiter: ","
## chr (1): ASV
## 
## ℹ Use `spec()` to retrieve the full column specification for this data.
## ℹ Specify the column types or set `show_col_types = FALSE` to quiet this message.
# subset ASV columns for Logistic Regression based on clade C PCA results in Dimension 1
balanced_df %>% 
  select(sample_id, Clade, (clade_c_pca_Ranks$ASV)) -> lr_data
#glimpse(lr_data)
head(lr_data)
## # A tibble: 6 × 3,228
##   sample_id  Clade ASV1236 ASV0421 ASV0691 ASV0899 ASV1004 ASV1041 ASV1058
##   <chr>      <chr>   <dbl>   <dbl>   <dbl>   <dbl>   <dbl>   <dbl>   <dbl>
## 1 SKAU-R2-23 C           0       0       0       0       0       0       0
## 2 SWAJ-R4-3  A           0       0       0       0       0       0       0
## 3 SYAN-R3-19 C           0       0       0       0       0       0       0
## 4 PMAQ-R2-19 A           0       0       0       0       0       0       0
## 5 SDOG-R3-6  A           0       0       0       0       0       0       0
## 6 PDOG-R2-22 A         234     147      90     103      60      42      49
## # ℹ 3,219 more variables: ASV12542 <dbl>, ASV1294 <dbl>, ASV13113 <dbl>,
## #   ASV1318 <dbl>, ASV2269 <dbl>, ASV2542 <dbl>, ASV2660 <dbl>, ASV2737 <dbl>,
## #   ASV2840 <dbl>, ASV3053 <dbl>, ASV3077 <dbl>, ASV3134 <dbl>, ASV3140 <dbl>,
## #   ASV3579 <dbl>, ASV6119 <dbl>, ASV7557 <dbl>, ASV8422 <dbl>, ASV1086 <dbl>,
## #   ASV1310 <dbl>, ASV15750 <dbl>, ASV16905 <dbl>, ASV2033 <dbl>,
## #   ASV2089 <dbl>, ASV2127 <dbl>, ASV2725 <dbl>, ASV2804 <dbl>, ASV3075 <dbl>,
## #   ASV3327 <dbl>, ASV3342 <dbl>, ASV3532 <dbl>, ASV3600 <dbl>, …
lr_data %>% 
  mutate(Clade = case_when(Clade=="C" ~ 1, 
                           .default = 0)) -> lr_data

Double-check if any columns sum to 0

# take out sample and clade columns for numeric only
map(lr_data[,-c(1,2)], ~sum(.)) %>% 
  as.data.frame() %>% 
  pivot_longer(cols = everything()) %>% 
  filter(value==0)
## # A tibble: 0 × 2
## # ℹ 2 variables: name <chr>, value <dbl>
dim(lr_data)
## [1]  278 3228

  • No columns sum to 0. This had been taken care of when subsetting for Clade C to have ASVs sequenced in Clade C.

  • There is sequencing data for Clade C and non-Clade C observations that are all non-zero when summing each ASV column.

dim(lr_data)
## [1]  278 3228

Inserted this afterwards to be able to work on Random Forest modeling

write_csv(lr_data, "../output/lr_data.csv")

t-SNE plot of Clade C and non-Clade C

library(tsne)
library(plotly)
## 
## Attaching package: 'plotly'
## The following object is masked from 'package:ggplot2':
## 
##     last_plot
## The following object is masked from 'package:stats':
## 
##     filter
## The following object is masked from 'package:graphics':
## 
##     layout
data(lr_clr_df)
## Warning in data(lr_clr_df): data set 'lr_clr_df' not found
features <- subset(lr_clr_df, select = -c(1,2)) 

set.seed(0)
tsne <- tsne(features, initial_dims = 2)
## sigma summary: Min. : 0.0678215778208645 |1st Qu. : 0.0916334485210355 |Median : 0.106756334806171 |Mean : 0.145508390913786 |3rd Qu. : 0.136747935696713 |Max. : 1.33140136971437 |
## Epoch: Iteration #100 error is: 11.9931544984992
## Epoch: Iteration #200 error is: 0.176468277811214
## Epoch: Iteration #300 error is: 0.167732330784209
## Epoch: Iteration #400 error is: 0.165431266607314
## Epoch: Iteration #500 error is: 0.16515252252442
## Epoch: Iteration #600 error is: 0.165050262676511
## Epoch: Iteration #700 error is: 0.165008046466993
## Epoch: Iteration #800 error is: 0.164989381654186
## Epoch: Iteration #900 error is: 0.164981014702747
## Epoch: Iteration #1000 error is: 0.164977194945977
tsne <- data.frame(tsne)
pdb <- cbind(tsne,lr_clr_df$Clade)
options(warn = -1)
fig2 <-  plot_ly(data = pdb ,x =  ~X1, y = ~X2, type = 'scatter', mode = 'markers', split = ~lr_clr_df$Clade)

fig2 <- fig2 %>%
  layout(
    plot_bgcolor = "#e5ecf6"
  )

fig2

GGally::ggpairs for Clade C

# quick subset for visualization
subset_lr <- lr_clr_df[,-1] %>% 
  select(1:10)

GGally::ggpairs(subset_lr, aes(color = as.factor(Clade))) -> ggpairs_10_clade_c
## Registered S3 method overwritten by 'GGally':
##   method from   
##   +.gg   ggplot2
ggpairs_10_clade_c

ggsave("../plots/ggpairs_10_clade_c.png", width = 14, height = 12, plot = ggpairs_10_clade_c)

Separate Training and Testing for later after experimenting with whole dataset first

set.seed(1234)
Z <- sample(nrow(lr_clr_df), .85*nrow(lr_clr_df))
lr_train <- lr_clr_df[Z,]
lr_test <- lr_clr_df[-Z,]

# take a peek at training data
head(lr_train, 20)
## # A tibble: 20 × 3,228
##    sample_id  Clade ASV1236 ASV0421 ASV0691 ASV0899 ASV1004 ASV1041 ASV1058
##    <chr>      <dbl>   <dbl>   <dbl>   <dbl>   <dbl>   <dbl>   <dbl>   <dbl>
##  1 PWAJ-R3-8      0 -0.0759  -0.167  -0.135 -0.0486   0.122 -0.0382   0.130
##  2 SYAN-R1-11     1 -0.0759  -0.167  -0.135 -0.0486   0.122 -0.0382   0.130
##  3 SMAQ-R1-5      1 -0.0759  -0.167  -0.135 -0.0486   0.122 -0.0382   0.130
##  4 PWAJ-R3-1      0 -0.0759  -0.167  -0.135 -0.0486   0.122 -0.0382   0.130
##  5 SYAN-R1-16     1 -0.0759  -0.167  -0.135 -0.0486   0.122 -0.0382   0.130
##  6 PMAQ-R2-29     1 -0.0759  -0.167  -0.135 -0.0486   0.122 -0.0382   0.130
##  7 PMAQ-R1-4      1 -0.0759  -0.167  -0.135 -0.0486   0.122 -0.0382   0.130
##  8 PKAU-R3-3      0 -0.0759  -0.167  -0.135 -0.0486   0.122 -0.0382   0.130
##  9 SYAN-R4-3      0 -0.0759  -0.167  -0.135 -0.0486   0.122 -0.0382   0.130
## 10 PKAU-R1-17     0 -0.0759  -0.167  -0.135 -0.0486   0.122 -0.0382   0.130
## 11 SWAJ-R3-23     0 -0.0759  -0.167  -0.135 -0.0486   0.122 -0.0382   0.130
## 12 PMAQ-R2-19     0 -0.0759  -0.167  -0.135 -0.0486   0.122 -0.0382   0.130
## 13 SYAN-R1-12     1 -0.0759  -0.167  -0.135 -0.0486   0.122 -0.0382   0.130
## 14 PDOG-R1-29     0 -0.0759   5.72   -0.135 -7.66     0.122  8.87     0.130
## 15 PMAQ-R2-18     1 -0.0759  -0.167  -0.135 -0.0486   0.122 -0.0382   0.130
## 16 SFAR-R2-25     0 -0.0759  -0.167   4.11  -0.0486   0.122 -0.0382  -1.83 
## 17 SKAU-R2-31     0 -0.0759  -0.167  -0.135 -0.0486   0.122 -0.0382   0.130
## 18 SWAJ-R3-10     0 -0.0759  -0.167  -0.135 -0.0486   0.122 -0.0382   0.130
## 19 SYAN-R1-20     1 -0.0759  -0.167  -0.135 -0.0486   0.122 -0.0382   0.130
## 20 PMAQ-R2-7      0 -0.0759  -0.167  -0.135 -0.0486   0.122 -0.0382   0.130
## # ℹ 3,219 more variables: ASV12542 <dbl>, ASV1294 <dbl>, ASV13113 <dbl>,
## #   ASV1318 <dbl>, ASV2269 <dbl>, ASV2542 <dbl>, ASV2660 <dbl>, ASV2737 <dbl>,
## #   ASV2840 <dbl>, ASV3053 <dbl>, ASV3077 <dbl>, ASV3134 <dbl>, ASV3140 <dbl>,
## #   ASV3579 <dbl>, ASV6119 <dbl>, ASV7557 <dbl>, ASV8422 <dbl>, ASV1086 <dbl>,
## #   ASV1310 <dbl>, ASV15750 <dbl>, ASV16905 <dbl>, ASV2033 <dbl>,
## #   ASV2089 <dbl>, ASV2127 <dbl>, ASV2725 <dbl>, ASV2804 <dbl>, ASV3075 <dbl>,
## #   ASV3327 <dbl>, ASV3342 <dbl>, ASV3532 <dbl>, ASV3600 <dbl>, …
dim(lr_train)
## [1]  236 3228
dim(lr_test)
## [1]   42 3228

check label distribution of CLade C = 1 and Non-Clade-C = 0

ggplot(lr_clr_df, aes( x = Clade)) +
  geom_histogram(stat = 'count') +
  ggtitle("Label Distributions of Clade C = 1 vs. Non-Clade C = 0") +
  theme_bw()

Experiment with whole dataset based on CLR Transformation

glmnet::glmnet

3226

y = as.factor(lr_clr_df$Clade)
x = as.matrix(lr_clr_df[,-c(1,2)])

any(is.na(x))
## [1] FALSE
library(glmnet)
## Loading required package: Matrix
## 
## Attaching package: 'Matrix'
## The following objects are masked from 'package:tidyr':
## 
##     expand, pack, unpack
## Loaded glmnet 4.1-8
## 
## Attaching package: 'glmnet'
## The following object is masked from 'package:compositions':
## 
##     rmult
lr_model <- glmnet(x, y, 
                 family = "binomial", 
                 #alpha = 1 # lasso L1 norm
                 alpha = 0 # ridge L2 norm
                )
plot(lr_model)

summary(lr_model)
##            Length Class     Mode     
## a0            100 -none-    numeric  
## beta       322600 dgCMatrix S4       
## df            100 -none-    numeric  
## dim             2 -none-    numeric  
## lambda        100 -none-    numeric  
## dev.ratio     100 -none-    numeric  
## nulldev         1 -none-    numeric  
## npasses         1 -none-    numeric  
## jerr            1 -none-    numeric  
## offset          1 -none-    logical  
## classnames      2 -none-    character
## call            5 -none-    call     
## nobs            1 -none-    numeric
lr_model
## 
## Call:  glmnet(x = x, y = y, family = "binomial", alpha = 0) 
## 
##       Df  %Dev  Lambda
## 1   3226  0.00 161.800
## 2   3226  3.00 154.400
## 3   3226  3.13 147.400
## 4   3226  3.27 140.700
## 5   3226  3.42 134.300
## 6   3226  3.57 128.200
## 7   3226  3.73 122.400
## 8   3226  3.89 116.800
## 9   3226  4.06 111.500
## 10  3226  4.24 106.500
## 11  3226  4.42 101.600
## 12  3226  4.61  96.990
## 13  3226  4.81  92.590
## 14  3226  5.02  88.380
## 15  3226  5.24  84.360
## 16  3226  5.46  80.530
## 17  3226  5.69  76.870
## 18  3226  5.93  73.370
## 19  3226  6.18  70.040
## 20  3226  6.44  66.850
## 21  3226  6.71  63.820
## 22  3226  6.98  60.920
## 23  3226  7.27  58.150
## 24  3226  7.57  55.500
## 25  3226  7.88  52.980
## 26  3226  8.19  50.570
## 27  3226  8.52  48.270
## 28  3226  8.86  46.080
## 29  3226  9.21  43.990
## 30  3226  9.57  41.990
## 31  3226  9.95  40.080
## 32  3226 10.33  38.260
## 33  3226 10.73  36.520
## 34  3226 11.14  34.860
## 35  3226 11.56  33.270
## 36  3226 11.99  31.760
## 37  3226 12.43  30.320
## 38  3226 12.89  28.940
## 39  3226 13.36  27.620
## 40  3226 13.84  26.370
## 41  3226 14.33  25.170
## 42  3226 14.83  24.030
## 43  3226 15.35  22.930
## 44  3226 15.88  21.890
## 45  3226 16.42  20.900
## 46  3226 16.98  19.950
## 47  3226 17.54  19.040
## 48  3226 18.12  18.180
## 49  3226 18.71  17.350
## 50  3226 19.31  16.560
## 51  3226 19.92  15.810
## 52  3226 20.54  15.090
## 53  3226 21.18  14.400
## 54  3226 21.82  13.750
## 55  3226 22.47  13.120
## 56  3226 23.14  12.530
## 57  3226 23.81  11.960
## 58  3226 24.49  11.410
## 59  3226 25.19  10.900
## 60  3226 25.89  10.400
## 61  3226 26.59   9.928
## 62  3226 27.31   9.476
## 63  3226 28.03   9.046
## 64  3226 28.76   8.635
## 65  3226 29.50   8.242
## 66  3226 30.24   7.868
## 67  3226 30.98   7.510
## 68  3226 31.73   7.169
## 69  3226 32.49   6.843
## 70  3226 33.25   6.532
## 71  3226 34.01   6.235
## 72  3226 34.77   5.952
## 73  3226 35.54   5.681
## 74  3226 36.30   5.423
## 75  3226 37.07   5.176
## 76  3226 37.84   4.941
## 77  3226 38.61   4.716
## 78  3226 39.37   4.502
## 79  3226 40.14   4.297
## 80  3226 40.90   4.102
## 81  3226 41.67   3.916
## 82  3226 42.42   3.738
## 83  3226 43.18   3.568
## 84  3226 43.93   3.406
## 85  3226 44.68   3.251
## 86  3226 45.42   3.103
## 87  3226 46.16   2.962
## 88  3226 46.89   2.827
## 89  3226 47.47   2.699
## 90  3226 48.19   2.576
## 91  3226 48.91   2.459
## 92  3226 49.61   2.347
## 93  3226 50.31   2.241
## 94  3226 51.00   2.139
## 95  3226 51.69   2.042
## 96  3226 52.36   1.949
## 97  3226 53.03   1.860
## 98  3226 53.68   1.776
## 99  3226 54.33   1.695
## 100 3226 54.97   1.618

Cross-Validation

cv_results <- cv.glmnet(x, y,
                        family = "binomial",
                        nfolds = 10)
plot(cv_results)

cv_results
## 
## Call:  cv.glmnet(x = x, y = y, nfolds = 10, family = "binomial") 
## 
## Measure: Binomial Deviance 
## 
##      Lambda Index Measure      SE Nonzero
## min 0.06685    20   1.302 0.02499      18
## 1se 0.08838    14   1.322 0.01970       3
summary(lr_model)
##            Length Class     Mode     
## a0            100 -none-    numeric  
## beta       322600 dgCMatrix S4       
## df            100 -none-    numeric  
## dim             2 -none-    numeric  
## lambda        100 -none-    numeric  
## dev.ratio     100 -none-    numeric  
## nulldev         1 -none-    numeric  
## npasses         1 -none-    numeric  
## jerr            1 -none-    numeric  
## offset          1 -none-    logical  
## classnames      2 -none-    character
## call            5 -none-    call     
## nobs            1 -none-    numeric
best_lambda <- lr_model$lambda.min

# Refit the model with the selected lambda
best_model <- glmnet(x, y, family = "binomial", alpha = 0, lambda = best_lambda)

coefficients(best_model)[,1:12]
## 3227 x 12 sparse Matrix of class "dgCMatrix"
##   [[ suppressing 12 column names 's0', 's1', 's2' ... ]]
##                                                                    
## (Intercept) -1.249001e-16 -1.485397e-06 -1.713617e-06 -1.994138e-06
## ASV1236      3.133071e-38  1.908130e-04  1.998792e-04  2.089003e-04
## ASV0421     -5.547569e-38 -3.350813e-04 -3.510170e-04 -3.666903e-04
## ASV0691     -4.924975e-38 -2.896424e-04 -3.034079e-04 -3.165521e-04
## ASV0899     -1.324028e-39 -1.106490e-06 -1.150181e-06 -8.423284e-07
## ASV1004      6.299724e-38  3.812596e-04  3.993747e-04  4.172514e-04
## ASV1041     -4.258951e-38 -2.601709e-04 -2.725263e-04 -2.848550e-04
## ASV1058      5.855981e-38  3.551137e-04  3.719554e-04  3.886430e-04
## ASV12542     1.842670e-38  1.079264e-04  1.130596e-04  1.179279e-04
## ASV1294      6.764978e-38  4.142677e-04  4.339359e-04  4.536197e-04
## ASV13113     2.351661e-38  1.458535e-04  1.527909e-04  1.598135e-04
## ASV1318      5.929751e-38  3.623411e-04  3.795375e-04  3.967181e-04
## ASV2269     -1.761531e-38 -1.098832e-04 -1.150788e-04 -1.204113e-04
## ASV2542      3.703376e-38  2.338315e-04  2.449298e-04  2.564108e-04
## ASV2660     -3.447239e-38 -2.096052e-04 -2.195201e-04 -2.294065e-04
## ASV2737     -1.456066e-39 -1.367741e-05 -1.428706e-05 -1.518864e-05
## ASV2840      4.606802e-38  2.731776e-04  2.861168e-04  2.986311e-04
## ASV3053      2.609821e-39  1.393020e-05  1.460005e-05  1.514913e-05
## ASV3077      1.430712e-38  8.585485e-05  8.992082e-05  9.390237e-05
## ASV3134      4.753922e-38  2.982834e-04  3.124725e-04  3.270169e-04
## ASV3140      2.100119e-38  1.336623e-04  1.399884e-04  1.466031e-04
## ASV3579      7.918462e-39  5.166155e-05  5.415299e-05  5.676858e-05
## ASV6119     -1.761531e-38 -1.098826e-04 -1.150613e-04 -1.203916e-04
## ASV7557     -1.761531e-38 -1.098825e-04 -1.150525e-04 -1.203821e-04
## ASV8422      1.007031e-38  5.634432e-05  5.906750e-05  6.146692e-05
## ASV1086     -5.080525e-39 -2.910583e-05 -3.048988e-05 -3.176340e-05
## ASV1310      3.341700e-38  2.034198e-04  2.130823e-04  2.226822e-04
## ASV15750    -8.427200e-39 -5.330493e-05 -5.578787e-05 -5.841172e-05
## ASV16905    -1.761531e-38 -1.098822e-04 -1.150488e-04 -1.203771e-04
## ASV2033      3.219968e-38  1.981608e-04  2.076165e-04  2.170776e-04
## ASV2089      1.201683e-38  7.568921e-05  7.924489e-05  8.295371e-05
## ASV2127      4.826544e-38  2.909540e-04  3.047510e-04  3.183362e-04
## ASV2725      5.527505e-38  3.307507e-04  3.464588e-04  3.617712e-04
## ASV2804     -1.761531e-38 -1.098819e-04 -1.150462e-04 -1.203737e-04
## ASV3075      3.447315e-38  2.083974e-04  2.183021e-04  2.280642e-04
## ASV3327      3.161305e-38  1.954205e-04  2.047499e-04  2.141267e-04
## ASV3342      3.467863e-38  2.170442e-04  2.273305e-04  2.378866e-04
## ASV3532     -3.132836e-38 -1.949826e-04 -2.041960e-04 -2.136230e-04
## ASV3600      3.984828e-38  2.436328e-04  2.552341e-04  2.667875e-04
## ASV4013      3.390601e-38  2.047929e-04  2.145219e-04  2.241009e-04
## ASV4136      3.397772e-38  2.063844e-04  2.161372e-04  2.258593e-04
## ASV4195      1.761531e-38  1.098816e-04  1.150333e-04  1.203591e-04
## ASV4407     -1.761531e-38 -1.098815e-04 -1.150246e-04 -1.203496e-04
## ASV4717      1.290371e-39  2.551059e-06  2.738207e-06  2.584375e-06
## ASV6794      1.867634e-38  1.074894e-04  1.126327e-04  1.173874e-04
## ASV8324     -1.761531e-38 -1.098814e-04 -1.150221e-04 -1.203458e-04
## ASV8981     -5.080524e-39 -3.167254e-05 -3.309248e-05 -3.462509e-05
## ASV9859      1.271657e-38  8.098419e-05  8.489415e-05  8.890570e-05
## ASV0936     -2.763764e-38 -1.670378e-04 -1.749991e-04 -1.828183e-04
## ASV12683    -2.597726e-39 -1.968116e-05 -2.056413e-05 -2.169419e-05
## ASV1293      4.103429e-38  2.480806e-04  2.598015e-04  2.714219e-04
## ASV13055    -4.412996e-39 -2.855261e-05 -2.982406e-05 -3.125675e-05
## ASV17063    -1.761531e-38 -1.098810e-04 -1.150065e-04 -1.203283e-04
## ASV2228      1.761531e-38  1.098809e-04  1.149979e-04  1.203189e-04
## ASV2769     -3.595451e-39 -2.294309e-05 -2.394070e-05 -2.507630e-05
## ASV2803      8.703816e-39  4.729126e-05  4.959924e-05  5.153974e-05
## ASV2896      2.186891e-38  1.324738e-04  1.388159e-04  1.450406e-04
## ASV3062      6.184777e-39  3.940477e-05  4.135646e-05  4.330884e-05
## ASV3107      2.630824e-38  1.609503e-04  1.686230e-04  1.762622e-04
## ASV3265      5.341940e-38  3.213072e-04  3.364978e-04  3.514579e-04
## ASV3666     -1.114465e-39 -9.001639e-06 -9.355387e-06 -9.893566e-06
## ASV4497      1.264747e-38  7.556865e-05  7.920834e-05  8.270306e-05
## ASV6914     -6.022177e-39 -4.092110e-05 -4.279554e-05 -4.494452e-05
## ASV0576     -6.389199e-38 -3.785832e-04 -3.965166e-04 -4.138517e-04
## ASV0673      1.553071e-38  1.008247e-04  1.056149e-04  1.106971e-04
## ASV0772      1.888544e-38  1.124757e-04  1.178470e-04  1.230298e-04
## ASV0862     -1.577283e-38 -9.203229e-05 -9.637688e-05 -1.005122e-04
## ASV0898      1.494744e-38  9.645591e-05  1.010492e-04  1.058867e-04
## ASV0910      3.275872e-38  2.084996e-04  2.184185e-04  2.287337e-04
## ASV0964     -2.301490e-38 -1.374197e-04 -1.439205e-04 -1.502662e-04
## ASV10059     1.525478e-38  9.572315e-05  1.003210e-04  1.049947e-04
## ASV10263    -1.761531e-38 -1.098805e-04 -1.150437e-04 -1.203638e-04
## ASV1088      1.737606e-38  1.099024e-04  1.151404e-04  1.205475e-04
## ASV1101      3.039775e-38  1.861197e-04  1.949358e-04  2.037738e-04
## ASV1183      1.927595e-38  1.224131e-04  1.281763e-04  1.342157e-04
## ASV11956     8.034700e-39  4.304382e-05  4.512148e-05  4.685476e-05
## ASV12774    -2.459980e-39 -1.961180e-05 -2.050291e-05 -2.166437e-05
## ASV1321      7.011807e-39  4.626079e-05  4.851095e-05  5.088093e-05
## ASV13793    -1.761531e-38 -1.098803e-04 -1.150331e-04 -1.203513e-04
## ASV14482    -1.373377e-39 -1.250640e-05 -1.306283e-05 -1.386224e-05
## ASV15483     1.217911e-38  7.231745e-05  7.580862e-05  7.913316e-05
## ASV2062      7.731123e-38  4.751823e-04  4.976508e-04  5.203122e-04
## ASV2132      3.470506e-38  2.126693e-04  2.228237e-04  2.329410e-04
## ASV2413      5.051081e-38  3.050367e-04  3.194586e-04  3.337316e-04
## ASV2490      3.356463e-38  2.018648e-04  2.113825e-04  2.207810e-04
## ASV2594      1.808116e-38  1.084470e-04  1.136031e-04  1.186458e-04
## ASV2822     -1.761531e-38 -1.098802e-04 -1.150465e-04 -1.203640e-04
## ASV2863      3.096232e-38  1.890271e-04  1.979086e-04  2.068538e-04
## ASV2910      4.045912e-38  2.405403e-04  2.519731e-04  2.630313e-04
## ASV2980      1.459677e-38  9.109750e-05  9.536405e-05  9.977248e-05
## ASV3307      1.761531e-38  1.098801e-04  1.150317e-04  1.203474e-04
## ASV3474      2.664464e-38  1.679609e-04  1.759765e-04  1.842113e-04
## ASV3502      5.699692e-38  3.475411e-04  3.640307e-04  3.804674e-04
## ASV4236      2.952451e-38  1.762086e-04  1.844724e-04  1.926040e-04
## ASV4842     -9.516024e-39 -6.129490e-05 -6.417784e-05 -6.723812e-05
## ASV4894     -1.761531e-38 -1.098800e-04 -1.150410e-04 -1.203566e-04
## ASV5290      2.150314e-38  1.310240e-04  1.372811e-04  1.434766e-04
## ASV5501      4.076922e-39  2.364198e-05  2.476756e-05  2.582819e-05
## ASV5795      1.425114e-38  8.699871e-05  9.115383e-05  9.527840e-05
## ASV5987     -1.761531e-38 -1.098800e-04 -1.150439e-04 -1.203592e-04
## ASV6267     -1.761531e-38 -1.098799e-04 -1.150352e-04 -1.203498e-04
## ASV6862      3.472093e-38  2.049392e-04  2.146227e-04  2.239674e-04
## ASV7145      6.514140e-39  3.554432e-05  3.722396e-05  3.869644e-05
## ASV7673     -1.761531e-38 -1.098799e-04 -1.150327e-04 -1.203465e-04
## ASV7789      5.781709e-39  3.652998e-05  3.832847e-05  4.012932e-05
## ASV7809     -2.504185e-39 -1.615844e-05 -1.685826e-05 -1.765877e-05
## ASV8002     -1.761531e-38 -1.098798e-04 -1.150255e-04 -1.203385e-04
## ASV8205      1.018531e-38  5.796957e-05  6.078188e-05  6.331894e-05
## ASV9155     -1.330777e-38 -8.336974e-05 -8.725280e-05 -9.129843e-05
## ASV9221     -2.388223e-39 -1.750088e-05 -1.825110e-05 -1.922070e-05
## ASV9311     -1.761531e-38 -1.098798e-04 -1.150130e-04 -1.203241e-04
## ASV9557     -1.761531e-38 -1.098797e-04 -1.150043e-04 -1.203147e-04
## ASV9936     -1.761531e-38 -1.098797e-04 -1.149957e-04 -1.203052e-04
## ASV1445      3.997197e-38  2.472151e-04  2.589931e-04  2.708681e-04
## ASV4232      3.338541e-38  2.066920e-04  2.165692e-04  2.265191e-04
## ASV6479     -8.157800e-40 -2.493097e-06 -2.532985e-06 -2.507023e-06
## ASV0142     -9.010265e-38 -5.403408e-04 -5.658601e-04 -5.909421e-04
## ASV0378     -2.984397e-38 -1.778476e-04 -1.862181e-04 -1.944117e-04
## ASV1122      5.277825e-38  3.255943e-04  3.410660e-04  3.566641e-04
## ASV0123     -8.831622e-38 -5.296978e-04 -5.546679e-04 -5.792579e-04
## ASV2064      9.456684e-39  5.301739e-05  5.548838e-05  5.776865e-05
## ASV4459     -9.719539e-39 -6.191645e-05 -6.481169e-05 -6.786521e-05
## ASV0448      1.423142e-38  9.730411e-05  1.019918e-04  1.071318e-04
## ASV0397      3.967868e-38  2.464117e-04  2.581236e-04  2.699978e-04
## ASV0485      5.602948e-38  3.426509e-04  3.588641e-04  3.751107e-04
## ASV1566      4.654943e-38  2.831909e-04  2.966128e-04  3.099751e-04
## ASV1365      3.010399e-38  1.823497e-04  1.910279e-04  1.995947e-04
## ASV1065      6.170416e-38  3.797311e-04  3.976935e-04  4.158214e-04
## ASV0722     -1.470608e-39 -6.262697e-06 -6.580155e-06 -6.747648e-06
## ASV12660    -2.979446e-38 -1.821147e-04 -1.906855e-04 -1.993044e-04
## ASV0223     -1.235827e-39 -3.031397e-06 -3.188949e-06 -3.106707e-06
## ASV0229      2.730513e-38  1.712747e-04  1.794002e-04  1.877385e-04
## ASV0877     -1.108271e-38 -6.769687e-05 -7.078255e-05 -7.397489e-05
## ASV0983      5.740917e-38  3.500241e-04  3.665447e-04  3.830829e-04
## ASV0626     -1.988713e-38 -1.147856e-04 -1.200539e-04 -1.251382e-04
## ASV4146     -3.218327e-39 -2.169253e-05 -2.261841e-05 -2.373606e-05
## ASV4175     -3.481381e-38 -2.154629e-04 -2.255776e-04 -2.359138e-04
## ASV2082     -2.075558e-39 -1.215953e-05 -1.288176e-05 -1.344948e-05
## ASV2272      2.490583e-38  1.532060e-04  1.605229e-04  1.678489e-04
## ASV2245     -3.017452e-38 -1.869420e-04 -1.957014e-04 -2.046768e-04
## ASV0590     -1.761143e-38 -1.099843e-04 -1.153115e-04 -1.206595e-04
## ASV0217     -3.047970e-38 -1.700610e-04 -1.779596e-04 -1.851798e-04
## ASV0416      2.949399e-38  1.759130e-04  1.841390e-04  1.922388e-04
## ASV1056      3.274151e-38  2.065818e-04  2.165093e-04  2.266467e-04
## ASV7777     -3.002033e-38 -1.881333e-04 -1.969416e-04 -2.060851e-04
## ASV0455      5.747357e-39  3.878293e-05  4.053846e-05  4.255004e-05
## ASV0604      5.799389e-39  4.199783e-05  4.411789e-05  4.645530e-05
## ASV6100     -2.766616e-38 -1.747451e-04 -1.829192e-04 -1.914805e-04
## ASV11359    -3.118370e-38 -1.922464e-04 -2.012274e-04 -2.104055e-04
## ASV6604      2.173846e-38  1.362445e-04  1.427918e-04  1.494398e-04
## ASV5004     -1.832224e-38 -1.147961e-04 -1.201018e-04 -1.256695e-04
## ASV1483     -1.683076e-38 -1.048731e-04 -1.097285e-04 -1.147861e-04
## ASV9773     -3.550227e-38 -2.224048e-04 -2.328051e-04 -2.436099e-04
## ASV4059      2.938087e-39  2.166942e-05  2.278455e-05  2.401895e-05
## ASV1193      5.793652e-38  3.570573e-04  3.740185e-04  3.911103e-04
## ASV4610     -6.006542e-39 -3.358977e-05 -3.507643e-05 -3.649164e-05
## ASV0742     -2.298570e-38 -1.352354e-04 -1.414388e-04 -1.475650e-04
## ASV1502      8.007334e-41 -2.018574e-06 -2.048436e-06 -2.256775e-06
## ASV0195     -5.832160e-39 -3.817775e-05 -4.005520e-05 -4.200836e-05
## ASV1213      1.900259e-38  1.159335e-04  1.212323e-04  1.266999e-04
## ASV1648     -2.634404e-38 -1.651881e-04 -1.728848e-04 -1.809159e-04
## ASV6984     -1.961126e-38 -1.224858e-04 -1.281590e-04 -1.340814e-04
## ASV0396     -1.668481e-38 -8.824550e-05 -9.237634e-05 -9.586264e-05
## ASV4297      3.047471e-38  1.818746e-04  1.905123e-04  1.989174e-04
## ASV2622      6.888392e-38  4.157039e-04  4.353348e-04  4.547717e-04
## ASV3512      9.672295e-39  6.170919e-05  6.476444e-05  6.784317e-05
## ASV2411      2.270339e-38  1.436981e-04  1.504782e-04  1.575400e-04
## ASV2291     -5.441058e-39 -3.259435e-05 -3.430549e-05 -3.583662e-05
## ASV0807      2.604318e-38  1.710813e-04  1.792579e-04  1.879760e-04
## ASV1292      1.555548e-38  9.753626e-05  1.020515e-04  1.067900e-04
## ASV1035      7.560947e-39  4.426924e-05  4.631109e-05  4.829654e-05
## ASV0070     -1.712350e-38 -1.000053e-04 -1.046895e-04 -1.091994e-04
## ASV0255      6.544534e-39  3.876942e-05  4.054103e-05  4.229717e-05
## ASV0057     -7.196267e-38 -4.285801e-04 -4.487127e-04 -4.684465e-04
## ASV0077     -1.116893e-38 -6.375209e-05 -6.671409e-05 -6.951586e-05
## ASV0625      7.103019e-38  4.307026e-04  4.508887e-04  4.711143e-04
## ASV2464      3.477612e-38  2.107082e-04  2.205687e-04  2.304411e-04
## ASV1315      5.946957e-38  3.658819e-04  3.833229e-04  4.008168e-04
## ASV2673      4.308417e-38  2.728501e-04  2.858890e-04  2.993263e-04
## ASV2161      1.768595e-38  1.106146e-04  1.159388e-04  1.213288e-04
## ASV0337     -2.931708e-38 -1.804013e-04 -1.889920e-04 -1.976186e-04
## ASV7680     -3.404884e-38 -2.109050e-04 -2.207863e-04 -2.309086e-04
## ASV0611      7.352171e-38  4.551899e-04  4.768399e-04  4.987329e-04
## ASV3118     -2.500910e-38 -1.563259e-04 -1.636630e-04 -1.712368e-04
## ASV1284      2.644200e-38  1.698133e-04  1.777015e-04  1.861399e-04
## ASV0889      2.055484e-38  1.240192e-04  1.299302e-04  1.357367e-04
## ASV4649     -2.121874e-38 -1.334350e-04 -1.396531e-04 -1.461570e-04
## ASV1108     -2.641951e-38 -1.691723e-04 -1.771590e-04 -1.855655e-04
## ASV0738     -5.908183e-39 -2.232608e-05 -2.328415e-05 -2.363166e-05
## ASV0473      4.155210e-39  2.651319e-05  2.771962e-05  2.902249e-05
## ASV0598     -3.187637e-38 -1.903784e-04 -1.993192e-04 -2.081112e-04
## ASV0429      4.956004e-38  3.021205e-04  3.163934e-04  3.306756e-04
## ASV1549      4.785423e-38  3.029638e-04  3.174044e-04  3.323198e-04
## ASV1203      3.731441e-38  2.270297e-04  2.376808e-04  2.483789e-04
## ASV4532      1.922455e-39  9.742039e-06  1.024191e-05  1.061446e-05
## ASV0274     -3.852814e-38 -2.268601e-04 -2.375678e-04 -2.478942e-04
## ASV0163     -5.515623e-38 -3.265723e-04 -3.417881e-04 -3.567216e-04
## ASV1298      2.242946e-38  1.335094e-04  1.396940e-04  1.458234e-04
## ASV9424     -4.497007e-38 -2.815765e-04 -2.948104e-04 -3.084882e-04
## ASV0412      7.043598e-38  4.306329e-04  4.509837e-04  4.713910e-04
## ASV0284      3.217293e-38  1.916966e-04  2.006555e-04  2.094713e-04
## ASV0620     -2.264305e-38 -1.449064e-04 -1.517342e-04 -1.589238e-04
## ASV0153     -4.777492e-38 -2.976247e-04 -3.118823e-04 -3.262996e-04
## ASV0498      3.908578e-39  3.356086e-05  3.518858e-05  3.726213e-05
## ASV0097      3.406348e-38  2.116342e-04  2.216571e-04  2.318627e-04
## ASV0104     -1.612636e-37 -9.866334e-04 -1.033436e-03 -1.080279e-03
## ASV1282      2.775381e-38  1.740438e-04  1.823287e-04  1.908023e-04
## ASV3883     -1.582262e-38 -9.739174e-05 -1.019674e-04 -1.066007e-04
## ASV0801      1.543506e-38  1.024593e-04  1.072369e-04  1.125044e-04
## ASV1611     -6.138811e-38 -3.785988e-04 -3.964315e-04 -4.145358e-04
## ASV0227     -2.145864e-38 -1.339951e-04 -1.404496e-04 -1.469582e-04
## ASV0833      2.307460e-38  1.483528e-04  1.554610e-04  1.628793e-04
## ASV0718      5.752412e-38  3.576295e-04  3.745335e-04  3.917943e-04
## ASV1139      2.218115e-38  1.345399e-04  1.407152e-04  1.470250e-04
## ASV0766     -1.602961e-38 -9.573937e-05 -1.001708e-04 -1.045799e-04
## ASV2091      7.916680e-38  4.728297e-04  4.950704e-04  5.169244e-04
## ASV1238     -5.836449e-39 -2.519539e-05 -2.627115e-05 -2.693708e-05
## ASV9193     -6.133051e-39 -5.058371e-05 -5.289709e-05 -5.592828e-05
## ASV0290     -5.878822e-39 -3.657106e-05 -3.830559e-05 -4.006726e-05
## ASV0231      6.145335e-38  3.730930e-04  3.906422e-04  4.081818e-04
## ASV0185      8.140561e-39  6.997178e-05  7.346040e-05  7.781979e-05
## ASV2330      1.801334e-38  1.085559e-04  1.136958e-04  1.187700e-04
## ASV3119     -1.890145e-38 -1.245015e-04 -1.304466e-04 -1.368032e-04
## ASV2368     -2.727240e-38 -1.731298e-04 -1.812513e-04 -1.897805e-04
## ASV0122     -2.266189e-38 -1.366210e-04 -1.431297e-04 -1.495280e-04
## ASV1044      3.693122e-38  2.377824e-04  2.491504e-04  2.610585e-04
## ASV0160     -5.622767e-38 -3.319708e-04 -3.474935e-04 -3.626340e-04
## ASV0326      3.500982e-38  2.150877e-04  2.253922e-04  2.356572e-04
## ASV1388      6.164818e-38  3.768329e-04  3.946614e-04  4.125324e-04
## ASV0792      7.055394e-38  4.321274e-04  4.524060e-04  4.729240e-04
## ASV0036     -4.341619e-38 -2.723864e-04 -2.854195e-04 -2.987115e-04
## ASV2125      7.212501e-38  4.432122e-04  4.641907e-04  4.853310e-04
## ASV1075      1.338293e-38  8.438700e-05  8.845959e-05  9.261097e-05
## ASV0390      1.253755e-38  8.649706e-05  9.062149e-05  9.523436e-05
## ASV3790     -5.735622e-38 -3.478524e-04 -3.642354e-04 -3.805749e-04
## ASV1535     -4.340024e-39 -2.934157e-05 -3.072865e-05 -3.224505e-05
## ASV0263      1.187358e-38  7.549861e-05  7.900468e-05  8.272450e-05
## ASV0675      9.307161e-38  5.869000e-04  6.147258e-04  6.434752e-04
## ASV3348      8.656278e-39  5.676206e-05  5.957709e-05  6.248220e-05
## ASV0058     -9.122278e-38 -5.542065e-04 -5.803912e-04 -6.065049e-04
## ASV4142      2.292079e-38  1.369338e-04  1.433300e-04  1.496676e-04
## ASV0059     -7.879787e-38 -4.778106e-04 -5.003371e-04 -5.228036e-04
## ASV0013     -1.637259e-37 -1.000529e-03 -1.047869e-03 -1.095306e-03
## ASV0033     -4.719255e-38 -2.970738e-04 -3.112448e-04 -3.257886e-04
## ASV4354     -2.135964e-38 -1.289855e-04 -1.350251e-04 -1.410479e-04
## ASV0022     -4.986826e-38 -3.137377e-04 -3.286692e-04 -3.440166e-04
## ASV0134     -1.193838e-38 -7.946790e-05 -8.328511e-05 -8.740127e-05
## ASV0415     -1.175890e-38 -6.524544e-05 -6.823674e-05 -7.099703e-05
## ASV10103    -3.511087e-38 -2.175841e-04 -2.277866e-04 -2.382407e-04
## ASV1613      5.799264e-38  3.544322e-04  3.711184e-04  3.879239e-04
## ASV0135     -4.478038e-39 -2.235386e-05 -2.327640e-05 -2.407412e-05
## ASV0469     -7.254312e-38 -4.407074e-04 -4.613551e-04 -4.821060e-04
## ASV0471      4.519901e-38  2.830636e-04  2.964070e-04  3.101684e-04
## ASV0451     -1.173322e-38 -7.552499e-05 -7.920357e-05 -8.299647e-05
## ASV0747      1.684687e-38  1.052262e-04  1.102585e-04  1.153612e-04
## ASV1314     -2.604417e-38 -1.672703e-04 -1.751952e-04 -1.835350e-04
## ASV0425     -8.316441e-38 -4.982203e-04 -5.215712e-04 -5.446734e-04
## ASV0559     -4.740023e-38 -2.809371e-04 -2.940871e-04 -3.069570e-04
## ASV0148     -5.151179e-38 -3.068554e-04 -3.212242e-04 -3.353670e-04
## ASV0129     -2.643876e-38 -1.527733e-04 -1.598546e-04 -1.666589e-04
## ASV1072      2.514587e-38  1.478164e-04  1.547157e-04  1.614246e-04
## ASV2390      1.792174e-38  1.074626e-04  1.125188e-04  1.175095e-04
## ASV0548      5.195657e-38  3.228210e-04  3.381586e-04  3.537505e-04
## ASV0168     -7.970435e-38 -4.809453e-04 -5.035387e-04 -5.260302e-04
## ASV0066     -5.880654e-38 -3.604353e-04 -3.774670e-04 -3.946142e-04
## ASV0468     -2.156339e-38 -1.374983e-04 -1.439289e-04 -1.507360e-04
## ASV0172     -1.376210e-38 -7.536357e-05 -7.876430e-05 -8.189823e-05
## ASV0236     -3.246804e-38 -1.848785e-04 -1.933480e-04 -2.014219e-04
## ASV0250     -7.781599e-40  1.064916e-05  1.140286e-05  1.269085e-05
## ASV0338     -5.609719e-39 -2.150292e-05 -2.234912e-05 -2.272022e-05
## ASV0450     -2.980329e-40  6.505922e-07  6.766473e-07  8.291404e-07
## ASV0377      6.423902e-38  3.962228e-04  4.149100e-04  4.338702e-04
## ASV1022      1.776651e-38  1.123895e-04  1.176451e-04  1.231639e-04
## ASV6174     -4.557312e-39 -2.519413e-05 -2.636194e-05 -2.740783e-05
## ASV0786      7.561788e-39  4.544168e-05  4.753804e-05  4.964216e-05
## ASV0053     -7.710100e-38 -4.754753e-04 -4.979594e-04 -5.207254e-04
## ASV0697     -2.322761e-38 -1.374339e-04 -1.438288e-04 -1.501183e-04
## ASV0785      5.747145e-38  3.534627e-04  3.701702e-04  3.870603e-04
## ASV1967     -3.902972e-38 -2.362602e-04 -2.473833e-04 -2.584532e-04
## ASV0385     -1.854378e-38 -1.077010e-04 -1.127121e-04 -1.175483e-04
## ASV0295     -1.077806e-39 -5.647932e-07 -4.648935e-07 -1.809315e-07
## ASV0072     -6.300848e-38 -3.784808e-04 -3.961695e-04 -4.137835e-04
## ASV0157     -2.674913e-38 -1.542215e-04 -1.613766e-04 -1.682018e-04
## ASV0501      2.719653e-38  1.747943e-04  1.831613e-04  1.918597e-04
## ASV10729    -4.667636e-38 -2.907864e-04 -3.044920e-04 -3.185484e-04
## ASV1470      2.276183e-38  1.302711e-04  1.363659e-04  1.421027e-04
## ASV0050     -1.552864e-37 -9.448499e-04 -9.892959e-04 -1.033872e-03
## ASV0411     -4.571970e-39 -2.609942e-05 -2.726019e-05 -2.841990e-05
## ASV0549      2.846724e-38  1.803219e-04  1.889698e-04  1.978668e-04
## ASV0184      1.803143e-38  1.117796e-04  1.170233e-04  1.223970e-04
## ASV0705      2.127130e-38  1.358633e-04  1.423210e-04  1.490552e-04
## ASV1715      5.451392e-38  3.361116e-04  3.519646e-04  3.680526e-04
## ASV0603      6.303247e-39  4.262458e-05  4.460868e-05  4.683957e-05
## ASV0826      1.883618e-38  1.125511e-04  1.178142e-04  1.230145e-04
## ASV0034     -7.066366e-38 -4.294520e-04 -4.495333e-04 -4.697594e-04
## ASV0838      1.483163e-38  1.002198e-04  1.048840e-04  1.101080e-04
## ASV0614     -4.004712e-38 -2.483288e-04 -2.600223e-04 -2.719717e-04
## ASV0014     -1.504048e-37 -9.164003e-04 -9.594518e-04 -1.002748e-03
## ASV0585     -9.271648e-39 -5.332300e-05 -5.586263e-05 -5.822703e-05
## ASV0016     -1.536910e-37 -9.371017e-04 -9.810617e-04 -1.025367e-03
## ASV5394     -3.851025e-38 -2.406006e-04 -2.519566e-04 -2.636239e-04
## ASV0666      3.316568e-38  2.036369e-04  2.131640e-04  2.228547e-04
## ASV2085      1.443304e-38  8.064250e-05  8.424797e-05  8.768162e-05
## ASV0003     -1.408628e-37 -8.572970e-04 -8.974133e-04 -9.378609e-04
## ASV0346     -4.125123e-39 -1.569904e-05 -1.620287e-05 -1.645486e-05
## ASV0267     -2.302057e-38 -1.395672e-04 -1.459292e-04 -1.524801e-04
## ASV0353      2.834266e-38  1.857057e-04  1.946516e-04  2.040786e-04
## ASV2419      3.995432e-38  2.432256e-04  2.546035e-04  2.660830e-04
## ASV0447      1.710637e-38  1.149951e-04  1.206314e-04  1.266216e-04
## ASV0654      6.042853e-38  3.734896e-04  3.912007e-04  4.091166e-04
## ASV0151      8.512835e-39  5.777364e-05  6.070237e-05  6.374678e-05
## ASV0065     -5.669201e-38 -3.461521e-04 -3.624201e-04 -3.788220e-04
## ASV0527      4.097663e-38  2.533188e-04  2.652083e-04  2.773626e-04
## ASV4055     -1.480477e-38 -9.879033e-05 -1.035023e-04 -1.086177e-04
## ASV0166     -4.804275e-38 -2.823246e-04 -2.954621e-04 -3.082732e-04
## ASV0417     -4.017932e-38 -2.434224e-04 -2.548098e-04 -2.662381e-04
## ASV0078     -3.257390e-38 -1.951716e-04 -2.042386e-04 -2.132946e-04
## ASV0322     -3.965370e-38 -2.336693e-04 -2.445123e-04 -2.551464e-04
## ASV0156     -5.105976e-38 -3.021854e-04 -3.163015e-04 -3.301289e-04
## ASV0648     -4.488601e-38 -2.815331e-04 -2.948211e-04 -3.085289e-04
## ASV0407      3.103441e-39  1.594673e-05  1.675379e-05  1.736664e-05
## ASV2030     -1.031307e-38 -5.908804e-05 -6.186487e-05 -6.445575e-05
## ASV0300      2.546967e-38  1.675588e-04  1.756450e-04  1.841924e-04
## ASV1150     -3.852651e-39 -2.388806e-05 -2.492285e-05 -2.606333e-05
## ASV0958      2.664002e-38  1.720983e-04  1.803443e-04  1.889883e-04
## ASV0216     -4.906846e-38 -2.970148e-04 -3.107864e-04 -3.247076e-04
## ASV0446      6.489840e-38  4.110993e-04  4.306435e-04  4.508679e-04
## ASV0367     -2.295717e-38 -1.401058e-04 -1.466756e-04 -1.533092e-04
## ASV0200     -4.250453e-38 -2.571906e-04 -2.693018e-04 -2.813762e-04
## ASV0334     -2.377183e-38 -1.312540e-04 -1.371040e-04 -1.425932e-04
## ASV1311      3.031849e-38  1.901085e-04  1.989691e-04  2.082250e-04
## ASV0458      3.264472e-38  1.999219e-04  2.093654e-04  2.188590e-04
## ASV1371      9.212320e-40  3.311521e-06  3.485371e-06  3.524488e-06
## ASV0418      3.956423e-38  2.356465e-04  2.467002e-04  2.575574e-04
## ASV0004      4.709975e-38  2.863350e-04  2.998219e-04  3.133206e-04
## ASV1943      3.491045e-38  2.102337e-04  2.201953e-04  2.300059e-04
## ASV1495     -7.505106e-39 -5.146573e-05 -5.406239e-05 -5.680020e-05
## ASV0901     -5.270082e-38 -3.303631e-04 -3.460542e-04 -3.621541e-04
## ASV0628      3.182044e-38  1.948186e-04  2.038882e-04  2.131387e-04
## ASV0400      1.272268e-38  7.663183e-05  8.019290e-05  8.375242e-05
## ASV0116     -4.015755e-38 -2.468226e-04 -2.585522e-04 -2.703340e-04
## ASV0788      3.388298e-38  2.078331e-04  2.176368e-04  2.275228e-04
## ASV0117      2.104939e-38  1.337443e-04  1.401655e-04  1.467727e-04
## ASV3137      6.088051e-39  3.718533e-05  3.894216e-05  4.070913e-05
## ASV0001      5.769339e-38  3.493623e-04  3.656093e-04  3.820059e-04
## ASV1651      3.849282e-38  2.243828e-04  2.347810e-04  2.448570e-04
## ASV1692      3.916604e-38  2.479499e-04  2.597708e-04  2.719704e-04
## ASV0660      2.398237e-38  1.418857e-04  1.483790e-04  1.548412e-04
## ASV0508      3.230712e-39  1.886343e-05  1.973699e-05  2.058756e-05
## ASV1660     -1.583265e-38 -1.002010e-04 -1.050158e-04 -1.099384e-04
## ASV0233      8.806217e-39  5.639613e-05  5.912351e-05  6.193602e-05
## ASV1343     -4.010104e-38 -2.485290e-04 -2.602738e-04 -2.722284e-04
## ASV0209      3.847575e-38  2.347029e-04  2.455844e-04  2.566824e-04
## ASV0193     -4.956363e-38 -2.925623e-04 -3.061270e-04 -3.194692e-04
## ASV0357     -3.708285e-39 -2.267140e-05 -2.360777e-05 -2.467155e-05
## ASV0198      1.029473e-38  6.674760e-05  6.990145e-05  7.325478e-05
## ASV0007      5.469502e-38  3.317701e-04  3.471736e-04  3.627726e-04
## ASV1772     -5.550091e-39 -3.281374e-05 -3.434175e-05 -3.583937e-05
## ASV0009      5.167512e-38  3.133806e-04  3.278948e-04  3.426243e-04
## ASV0006      2.157679e-38  1.261948e-04  1.319045e-04  1.375939e-04
## ASV0011     -5.581552e-38 -3.476957e-04 -3.641205e-04 -3.809398e-04
## ASV0015      3.953436e-38  2.412701e-04  2.526181e-04  2.640382e-04
## ASV0017      4.193162e-38  2.555755e-04  2.675563e-04  2.796364e-04
## ASV0235     -3.262141e-38 -2.010908e-04 -2.105931e-04 -2.202013e-04
## ASV0382      4.625552e-39  3.805427e-05  4.008780e-05  4.239018e-05
## ASV2357      4.986866e-38  3.066749e-04  3.211235e-04  3.357566e-04
## ASV0567     -3.682815e-38 -2.245209e-04 -2.349885e-04 -2.456043e-04
## ASV0165      3.988685e-38  2.466771e-04  2.583012e-04  2.701330e-04
## ASV0005      8.107507e-38  4.899131e-04  5.127984e-04  5.357282e-04
## ASV0384     -4.532717e-39 -2.635055e-05 -2.744689e-05 -2.862139e-05
## ASV0002      1.659396e-38  1.033754e-04  1.083457e-04  1.133524e-04
## ASV3017      4.757079e-38  2.871443e-04  3.004565e-04  3.138786e-04
## ASV0091      1.764900e-38  1.099225e-04  1.151344e-04  1.204472e-04
## ASV0186     -4.797272e-38 -2.936992e-04 -3.075268e-04 -3.214729e-04
## ASV0370      4.710406e-39  3.179425e-05  3.326827e-05  3.493503e-05
## ASV0018      8.430121e-38  5.103113e-04  5.341430e-04  5.580739e-04
## ASV1377      7.378245e-38  4.483244e-04  4.692403e-04  4.903403e-04
## ASV0019      8.439473e-38  5.110415e-04  5.348692e-04  5.588407e-04
## ASV0023      7.066716e-39  3.723640e-05  3.870266e-05  4.015744e-05
## ASV2194      2.682544e-38  1.645285e-04  1.723438e-04  1.801905e-04
## ASV1155     -3.632665e-39 -1.644269e-05 -1.693904e-05 -1.741689e-05
## ASV0510     -3.222010e-38 -1.850802e-04 -1.933826e-04 -2.015493e-04
## ASV2371     -3.120574e-38 -1.855876e-04 -1.943048e-04 -2.028284e-04
## ASV0024      3.056467e-39  1.258259e-05  1.288875e-05  1.316739e-05
## ASV2452      4.023230e-38  2.423734e-04  2.535075e-04  2.648100e-04
## ASV2332      7.898870e-40  4.454049e-06  4.687266e-06  4.896315e-06
## ASV2591      5.921995e-40  9.353665e-06  9.817209e-06  1.056111e-05
## ASV0521      5.271635e-38  3.356814e-04  3.516266e-04  3.682314e-04
## ASV5542      1.600784e-38  1.007314e-04  1.054130e-04  1.103369e-04
## ASV0336     -2.531440e-38 -1.487600e-04 -1.556989e-04 -1.624494e-04
## ASV10102     3.682342e-38  2.273599e-04  2.380547e-04  2.489446e-04
## ASV16823    -3.040027e-38 -1.816058e-04 -1.901545e-04 -1.985402e-04
## ASV3104      3.040027e-38  1.816058e-04  1.901401e-04  1.985254e-04
## ASV0781      1.428856e-38  8.978916e-05  9.392981e-05  9.830947e-05
## ASV10899     1.253085e-38  8.251082e-05  8.648541e-05  9.070610e-05
## ASV11222    -3.040027e-38 -1.816057e-04 -1.901301e-04 -1.985155e-04
## ASV11327    -3.040027e-38 -1.816057e-04 -1.901157e-04 -1.985007e-04
## ASV12458    -3.040027e-38 -1.816057e-04 -1.901014e-04 -1.984859e-04
## ASV1636     -2.490636e-38 -1.473258e-04 -1.541186e-04 -1.608421e-04
## ASV1890     -3.007323e-38 -1.802957e-04 -1.887430e-04 -1.971024e-04
## ASV2898      6.377943e-38  3.901464e-04  4.083080e-04  4.268041e-04
## ASV8328     -6.226076e-39 -3.074176e-05 -3.205837e-05 -3.313068e-05
## ASV0709     -5.198536e-38 -3.162657e-04 -3.309510e-04 -3.458579e-04
## ASV0856      7.771543e-39  5.220046e-05  5.469911e-05  5.741924e-05
## ASV0909     -2.335561e-38 -1.332493e-04 -1.391533e-04 -1.449715e-04
## ASV0937     -4.008191e-38 -2.468551e-04 -2.585640e-04 -2.703633e-04
## ASV11390    -3.040027e-38 -1.816057e-04 -1.900705e-04 -1.984544e-04
## ASV11966     1.420327e-38  8.864796e-05  9.287905e-05  9.717595e-05
## ASV12990     7.819545e-39  4.991026e-05  5.218436e-05  5.465849e-05
## ASV14797     3.089629e-38  1.876378e-04  1.962542e-04  2.050778e-04
## ASV14904    -3.040027e-38 -1.816057e-04 -1.900659e-04 -1.984501e-04
## ASV15304     7.030854e-39  4.543215e-05  4.763947e-05  4.992105e-05
## ASV16696    -3.040027e-38 -1.816057e-04 -1.900538e-04 -1.984376e-04
## ASV1690      1.419706e-38  9.174082e-05  9.617471e-05  1.007830e-04
## ASV2029      8.151639e-38  4.991662e-04  5.224501e-04  5.461442e-04
## ASV2834      4.329441e-38  2.644228e-04  2.768741e-04  2.893921e-04
## ASV4003      1.121142e-38  7.697683e-05  8.073933e-05  8.483649e-05
## ASV4064      2.989265e-38  1.823310e-04  1.909140e-04  1.995361e-04
## ASV4294      9.589711e-39  6.612541e-05  6.935098e-05  7.288309e-05
## ASV4609     -1.530065e-39 -8.970031e-06 -9.447212e-06 -9.848408e-06
## ASV6283     -3.040027e-38 -1.816056e-04 -1.900507e-04 -1.984353e-04
## ASV6491     -3.040027e-38 -1.816056e-04 -1.900364e-04 -1.984205e-04
## ASV7453      1.059821e-38  7.131683e-05  7.478970e-05  7.850883e-05
## ASV7959      1.319226e-39  1.211791e-05  1.278039e-05  1.356726e-05
## ASV8219      3.040027e-38  1.816056e-04  1.900260e-04  1.984100e-04
## ASV8547     -3.040027e-38 -1.816055e-04 -1.900118e-04 -1.983952e-04
## ASV9319      1.938115e-38  1.192701e-04  1.248803e-04  1.305739e-04
## ASV9382     -3.040027e-38 -1.816055e-04 -1.900028e-04 -1.983858e-04
## ASV11516    -3.040027e-38 -1.816055e-04 -1.899886e-04 -1.983710e-04
## ASV14377    -3.040027e-38 -1.816055e-04 -1.899745e-04 -1.983562e-04
## ASV1867      4.243133e-38  2.644953e-04  2.769743e-04  2.897777e-04
## ASV1895     -1.045979e-38 -6.231039e-05 -6.513977e-05 -6.800805e-05
## ASV3168      1.850837e-38  1.116336e-04  1.167676e-04  1.219766e-04
## ASV4449      3.739630e-38  2.256396e-04  2.361050e-04  2.466407e-04
## ASV6596      1.994017e-38  1.316071e-04  1.379751e-04  1.447298e-04
## ASV7492     -1.214220e-38 -6.866030e-05 -7.167701e-05 -7.463527e-05
## ASV9854     -1.586802e-38 -9.325314e-05 -9.752740e-05 -1.017487e-04
## ASV6296      3.040027e-38  1.816054e-04  1.899442e-04  1.983249e-04
## ASV4201      8.213575e-39  5.835409e-05  6.136111e-05  6.456077e-05
## ASV0552      7.091608e-38  4.432578e-04  4.642355e-04  4.857454e-04
## ASV3671     -6.933592e-39 -3.624613e-05 -3.779886e-05 -3.919287e-05
## ASV3529     -7.618069e-39 -4.203533e-05 -4.379078e-05 -4.554131e-05
## ASV1060      1.780419e-38  1.129075e-04  1.182714e-04  1.238409e-04
## ASV0239     -4.212994e-38 -2.473585e-04 -2.586896e-04 -2.698806e-04
## ASV5711     -3.858562e-38 -2.315608e-04 -2.422552e-04 -2.530004e-04
## ASV4152     -5.028716e-38 -3.038987e-04 -3.180465e-04 -3.322610e-04
## ASV1461      4.545945e-38  2.727193e-04  2.852235e-04  2.978739e-04
## ASV2877      3.640261e-38  2.205385e-04  2.308062e-04  2.411530e-04
## ASV0012      2.642182e-38  1.646279e-04  1.725240e-04  1.804946e-04
## ASV9823      1.022522e-38  5.273385e-05  5.510182e-05  5.712244e-05
## ASV0008      2.903262e-38  1.799787e-04  1.885585e-04  1.972246e-04
## ASV7832     -3.117744e-38 -1.892889e-04 -1.980640e-04 -2.069603e-04
## ASV1915      1.884721e-39  1.453690e-05  1.533166e-05  1.617929e-05
## ASV0055      2.110467e-38  1.295340e-04  1.356041e-04  1.417693e-04
## ASV0032      5.174495e-38  3.182277e-04  3.329563e-04  3.481348e-04
## ASV2977     -4.236458e-38 -2.561868e-04 -2.680906e-04 -2.800792e-04
## ASV0466      4.341784e-38  2.584954e-04  2.703848e-04  2.822701e-04
## ASV3866      4.428837e-38  2.757829e-04  2.887837e-04  3.021166e-04
## ASV0040      5.852469e-38  3.618329e-04  3.789791e-04  3.963430e-04
## ASV0496     -2.206917e-39 -2.025217e-05 -2.142206e-05 -2.273831e-05
## ASV0052      7.282631e-38  4.427894e-04  4.634220e-04  4.842789e-04
## ASV3828     -4.522951e-38 -2.767072e-04 -2.895403e-04 -3.026624e-04
## ASV1930      2.768340e-38  1.724932e-04  1.806022e-04  1.889419e-04
## ASV2126      4.533398e-38  2.786916e-04  2.917079e-04  3.049967e-04
## ASV0793      2.607435e-38  1.624860e-04  1.703365e-04  1.782080e-04
## ASV0299     -2.003054e-38 -1.163024e-04 -1.215117e-04 -1.266928e-04
## ASV0208      4.123216e-38  2.638663e-04  2.764347e-04  2.895538e-04
## ASV0511     -2.426196e-38 -1.401264e-04 -1.463814e-04 -1.525897e-04
## ASV1123     -3.131395e-38 -1.832762e-04 -1.916147e-04 -1.998735e-04
## ASV0099     -1.685390e-38 -9.831966e-05 -1.028649e-04 -1.072793e-04
## ASV0752     -2.883957e-39 -2.132435e-05 -2.242819e-05 -2.363655e-05
## ASV0883      1.221272e-40  1.167877e-06  1.268838e-06  1.350132e-06
## ASV0683      3.687287e-38  2.341418e-04  2.452850e-04  2.568434e-04
## ASV4117     -4.545179e-38 -2.736963e-04 -2.863986e-04 -2.991478e-04
## ASV2172      1.665364e-38  1.022156e-04  1.070225e-04  1.118956e-04
## ASV0330     -3.022947e-38 -1.872858e-04 -1.961016e-04 -2.051206e-04
## ASV0728      2.813973e-38  1.682685e-04  1.762921e-04  1.840882e-04
## ASV0499      5.569071e-38  3.540901e-04  3.709364e-04  3.884399e-04
## ASV0120     -6.313502e-38 -3.869041e-04 -4.050074e-04 -4.233847e-04
## ASV1446      6.044190e-39  3.293011e-05  3.431087e-05  3.565411e-05
## ASV17171    -4.305784e-38 -2.631985e-04 -2.754397e-04 -2.879063e-04
## ASV0533      1.169723e-38  7.505609e-05  7.866155e-05  8.240212e-05
## ASV2495     -1.703725e-38 -1.051715e-04 -1.101609e-04 -1.152012e-04
## ASV5582      1.573573e-38  9.156779e-05  9.569328e-05  9.979612e-05
## ASV1488      1.333731e-38  9.229115e-05  9.668644e-05  1.015874e-04
## ASV0682      3.878487e-38  2.469472e-04  2.586897e-04  2.709064e-04
## ASV0068     -1.569197e-39 -1.327735e-05 -1.407600e-05 -1.489705e-05
## ASV1987     -2.040273e-38 -1.306435e-04 -1.369790e-04 -1.434865e-04
## ASV0035      8.741778e-39  4.712766e-05  4.904687e-05  5.093719e-05
## ASV7192     -2.954758e-38 -1.754259e-04 -1.834718e-04 -1.915077e-04
## ASV0873      4.983130e-39  2.665061e-05  2.774500e-05  2.880668e-05
## ASV4749      3.649700e-39  1.724434e-05  1.777253e-05  1.831644e-05
## ASV2174      2.827707e-38  1.612881e-04  1.686144e-04  1.756886e-04
## ASV1476     -2.364743e-38 -1.437480e-04 -1.504985e-04 -1.572720e-04
## ASV0740     -5.655336e-38 -3.553192e-04 -3.721970e-04 -3.895430e-04
## ASV0170      1.225668e-38  7.571096e-05  7.925957e-05  8.288978e-05
## ASV2466     -5.252633e-38 -3.241162e-04 -3.392566e-04 -3.547737e-04
## ASV1709      4.103967e-38  2.498180e-04  2.614230e-04  2.732038e-04
## ASV6170     -3.701779e-38 -2.128933e-04 -2.229287e-04 -2.323773e-04
## ASV3673      4.233390e-38  2.539371e-04  2.659118e-04  2.777301e-04
## ASV1745      3.214905e-39  1.590267e-05  1.665546e-05  1.723721e-05
## ASV0380     -3.001704e-38 -1.700805e-04 -1.780522e-04 -1.854702e-04
## ASV0426     -9.429897e-39 -5.168855e-05 -5.416699e-05 -5.631987e-05
## ASV0202     -1.061039e-38 -5.271781e-05 -5.478559e-05 -5.664562e-05
## ASV6350     -3.682451e-38 -2.137760e-04 -2.238166e-04 -2.334157e-04
## ASV0713     -2.510054e-38 -1.523945e-04 -1.595707e-04 -1.667508e-04
## ASV1822      4.504880e-39  3.015101e-05  3.152317e-05  3.306624e-05
## ASV4569      4.087268e-38  2.466144e-04  2.581365e-04  2.696747e-04
## ASV0030     -8.372670e-39 -5.483193e-05 -5.756273e-05 -6.034441e-05
## ASV0331      1.553491e-38  1.020945e-04  1.070113e-04  1.122253e-04
## ASV2981      3.971736e-38  2.500761e-04  2.618795e-04  2.740955e-04
## ASV0828     -2.616058e-38 -1.666931e-04 -1.746126e-04 -1.828580e-04
## ASV2440      6.289782e-38  3.958041e-04  4.145137e-04  4.338545e-04
## ASV3006     -3.040027e-38 -1.725744e-04 -1.806531e-04 -1.881999e-04
## ASV3875     -3.040027e-38 -1.725743e-04 -1.806396e-04 -1.881867e-04
## ASV4511      1.544893e-38  9.942746e-05  1.041744e-04  1.091458e-04
## ASV4700     -3.040027e-38 -1.725742e-04 -1.806263e-04 -1.881735e-04
## ASV5804     -3.040027e-38 -1.725741e-04 -1.806128e-04 -1.881603e-04
## ASV6826      2.879466e-38  1.833668e-04  1.920604e-04  2.011338e-04
## ASV7280      2.393345e-38  1.516116e-04  1.587731e-04  1.662065e-04
## ASV7535     -3.040027e-38 -1.725739e-04 -1.806052e-04 -1.881535e-04
## ASV0651     -2.961384e-38 -1.785018e-04 -1.866562e-04 -1.949689e-04
## ASV0913      3.794294e-38  2.397244e-04  2.510837e-04  2.628591e-04
## ASV10832    -3.040027e-38 -1.725738e-04 -1.805924e-04 -1.881409e-04
## ASV1117     -5.631066e-38 -3.409692e-04 -3.569841e-04 -3.729978e-04
## ASV11329     1.146426e-38  8.313713e-05  8.723193e-05  9.183052e-05
## ASV13209    -3.629118e-39 -1.101355e-05 -1.144232e-05 -1.143216e-05
## ASV1345      6.318447e-39  4.167074e-05  4.371111e-05  4.581998e-05
## ASV1719     -3.040027e-38 -1.725736e-04 -1.805710e-04 -1.881204e-04
## ASV1886      3.242222e-38  1.968181e-04  2.060046e-04  2.152857e-04
## ASV2158     -9.398753e-39 -4.735831e-05 -4.944854e-05 -5.121795e-05
## ASV2189      3.410635e-38  2.105452e-04  2.204425e-04  2.305358e-04
## ASV2257      2.584074e-38  1.553533e-04  1.627000e-04  1.699519e-04
## ASV2283      3.040027e-38  1.725733e-04  1.805420e-04  1.880912e-04
## ASV2328      3.040027e-38  1.725732e-04  1.805287e-04  1.880780e-04
## ASV2434     -4.282884e-38 -2.544423e-04 -2.663459e-04 -2.780694e-04
## ASV2648      3.040027e-38  1.725730e-04  1.805005e-04  1.880493e-04
## ASV2698      3.969934e-38  2.469916e-04  2.586317e-04  2.705735e-04
## ASV2775      5.017817e-38  2.962196e-04  3.098203e-04  3.233336e-04
## ASV3171      3.040027e-38  1.725728e-04  1.804737e-04  1.880219e-04
## ASV3227      3.740920e-38  2.188728e-04  2.288626e-04  2.387423e-04
## ASV3397      1.862479e-39  1.301832e-05  1.374450e-05  1.442585e-05
## ASV3444      4.180246e-38  2.463463e-04  2.577821e-04  2.690312e-04
## ASV3556      3.040027e-38  1.725725e-04  1.804402e-04  1.879878e-04
## ASV3606     -3.040027e-38 -1.725724e-04 -1.804271e-04 -1.879745e-04
## ASV4190      3.521442e-38  2.170331e-04  2.272747e-04  2.376664e-04
## ASV4197      4.290482e-38  2.516150e-04  2.632849e-04  2.746964e-04
## ASV4722      3.727856e-38  2.263866e-04  2.369751e-04  2.476386e-04
## ASV4765      8.670616e-39  5.698417e-05  5.964630e-05  6.252401e-05
## ASV4809      3.040027e-38  1.725721e-04  1.803952e-04  1.879420e-04
## ASV4846      2.572609e-38  1.608783e-04  1.684186e-04  1.762153e-04
## ASV4903     -9.356722e-39 -4.539714e-05 -4.732798e-05 -4.891844e-05
## ASV4944     -3.040027e-38 -1.725718e-04 -1.803816e-04 -1.879289e-04
## ASV5151     -8.791479e-39 -6.353048e-05 -6.676382e-05 -7.025405e-05
## ASV5413     -3.040027e-38 -1.725717e-04 -1.803715e-04 -1.879190e-04
## ASV5537     -3.040027e-38 -1.725715e-04 -1.803584e-04 -1.879058e-04
## ASV5688      3.040027e-38  1.725714e-04  1.803454e-04  1.878926e-04
## ASV5752      1.243878e-38  8.047345e-05  8.444768e-05  8.846563e-05
## ASV6122     -3.040027e-38 -1.725712e-04 -1.803356e-04 -1.878826e-04
## ASV6135      3.040027e-38  1.725711e-04  1.803226e-04  1.878694e-04
## ASV6188     -3.040027e-38 -1.725709e-04 -1.803096e-04 -1.878562e-04
## ASV6216      4.291012e-38  2.537348e-04  2.653846e-04  2.770036e-04
## ASV6242      3.040027e-38  1.725707e-04  1.802827e-04  1.878284e-04
## ASV6383      3.040027e-38  1.725705e-04  1.802698e-04  1.878152e-04
## ASV6781      3.040027e-38  1.725704e-04  1.802570e-04  1.878019e-04
## ASV6799     -3.040027e-38 -1.725702e-04 -1.802441e-04 -1.877887e-04
## ASV7374     -3.040027e-38 -1.725701e-04 -1.802313e-04 -1.877755e-04
## ASV7539     -3.040027e-38 -1.725699e-04 -1.802185e-04 -1.877623e-04
## ASV8591     -3.040027e-38 -1.725698e-04 -1.802057e-04 -1.877491e-04
## ASV8637      3.040027e-38  1.725696e-04  1.801930e-04  1.877359e-04
## ASV12796    -3.040027e-38 -1.725695e-04 -1.801802e-04 -1.877227e-04
## ASV1934      3.168520e-38  1.970552e-04  2.063213e-04  2.158377e-04
## ASV22549    -2.606906e-40  9.670218e-06  1.051748e-05  1.152407e-05
## ASV29857    -3.040027e-38 -1.725693e-04 -1.801678e-04 -1.877099e-04
## ASV3215      3.810256e-38  2.392691e-04  2.506358e-04  2.623158e-04
## ASV3236     -3.040027e-38 -1.725691e-04 -1.801543e-04 -1.876959e-04
## ASV3954     -3.040027e-38 -1.725690e-04 -1.801416e-04 -1.876827e-04
## ASV4850      3.040027e-38  1.725688e-04  1.801289e-04  1.876694e-04
## ASV5225      3.040027e-38  1.725687e-04  1.801163e-04  1.876562e-04
## ASV5532     -3.040027e-38 -1.725685e-04 -1.801037e-04 -1.876430e-04
## ASV7258      7.356746e-40  1.915640e-05  2.058205e-05  2.222498e-05
## ASV9474     -1.829704e-38 -9.919263e-05 -1.032942e-04 -1.073851e-04
## ASV11857    -3.040027e-38 -1.725682e-04 -1.800863e-04 -1.876251e-04
## ASV1202     -3.040027e-38 -1.725680e-04 -1.800738e-04 -1.876119e-04
## ASV14742     1.797837e-38  1.200694e-04  1.260241e-04  1.322317e-04
## ASV16652     9.184402e-39  6.096820e-05  6.408570e-05  6.719856e-05
## ASV2019      4.207641e-38  2.509927e-04  2.624399e-04  2.740367e-04
## ASV2410     -3.812021e-38 -2.327353e-04 -2.435655e-04 -2.545982e-04
## ASV2718      3.875721e-38  2.468730e-04  2.586857e-04  2.708855e-04
## ASV2738      4.796396e-38  2.820255e-04  2.947610e-04  3.075642e-04
## ASV2876      3.040027e-38  1.725677e-04  1.800462e-04  1.875830e-04
## ASV3177      3.040027e-38  1.725675e-04  1.800337e-04  1.875698e-04
## ASV4367      3.040027e-38  1.725674e-04  1.800212e-04  1.875566e-04
## ASV4635      7.220246e-39  5.694731e-05  6.011270e-05  6.343929e-05
## ASV4896     -4.249857e-40  1.265703e-05  1.383572e-05  1.520452e-05
## ASV4907      1.825889e-38  1.236633e-04  1.299764e-04  1.364454e-04
## ASV5230     -3.040027e-38 -1.725670e-04 -1.800199e-04 -1.875557e-04
## ASV6509     -3.040027e-38 -1.725669e-04 -1.800075e-04 -1.875425e-04
## ASV7376     -3.040027e-38 -1.725668e-04 -1.799950e-04 -1.875293e-04
## ASV8163     -3.040027e-38 -1.725666e-04 -1.799826e-04 -1.875161e-04
## ASV8195     -3.040027e-38 -1.725665e-04 -1.799702e-04 -1.875029e-04
## ASV8923      1.564948e-38  1.032958e-04  1.084568e-04  1.137290e-04
## ASV9666     -2.728745e-38 -1.533035e-04 -1.597881e-04 -1.663947e-04
## ASV1482      2.477237e-38  1.536848e-04  1.610560e-04  1.684482e-04
## ASV2726      3.190156e-38  2.024051e-04  2.121706e-04  2.221352e-04
## ASV3281     -3.040027e-38 -1.725661e-04 -1.799566e-04 -1.874884e-04
## ASV4235     -3.040027e-38 -1.725660e-04 -1.799443e-04 -1.874752e-04
## ASV4808      4.286934e-38  2.531235e-04  2.645285e-04  2.760868e-04
## ASV4861     -4.283689e-38 -2.545215e-04 -2.659620e-04 -2.776749e-04
## ASV5276      4.241240e-38  2.498318e-04  2.610595e-04  2.724293e-04
## ASV5837      3.436592e-38  2.151666e-04  2.253102e-04  2.357860e-04
## ASV7098      3.525946e-38  2.201664e-04  2.304961e-04  2.411844e-04
## ASV8451     -3.040027e-38 -1.725656e-04 -1.798881e-04 -1.874152e-04
## ASV8694     -3.040027e-38 -1.725655e-04 -1.798759e-04 -1.874020e-04
## ASV0905     -1.429364e-38 -9.053140e-05 -9.490064e-05 -9.932495e-05
## ASV2900      3.647573e-38  2.112101e-04  2.203553e-04  2.297881e-04
## ASV3963     -2.964512e-38 -1.678785e-04 -1.749435e-04 -1.822418e-04
## ASV0041     -2.938907e-38 -1.842951e-04 -1.932438e-04 -2.022165e-04
## ASV1865      2.859714e-38  1.874174e-04  1.967012e-04  2.062216e-04
## ASV1140      2.402015e-38  1.505695e-04  1.579443e-04  1.652547e-04
## ASV1179      3.553674e-38  2.225193e-04  2.330878e-04  2.439089e-04
## ASV0279      5.181018e-38  3.145806e-04  3.291163e-04  3.439316e-04
## ASV0043     -3.287927e-39 -2.794899e-05 -2.957691e-05 -3.132549e-05
## ASV2097     -2.989356e-38 -1.770582e-04 -1.849002e-04 -1.930201e-04
## ASV0309     -1.502889e-38 -8.795473e-05 -9.198217e-05 -9.596191e-05
## ASV0607      6.090462e-38  3.829983e-04  4.010643e-04  4.197686e-04
## ASV0025     -6.402158e-38 -4.010868e-04 -4.202133e-04 -4.397201e-04
## ASV2284     -1.239649e-38 -6.460212e-05 -6.744462e-05 -6.995858e-05
## ASV0556      9.864971e-39  6.777759e-05  7.110656e-05  7.469399e-05
## ASV5040      2.597255e-38  1.452080e-04  1.512023e-04  1.574132e-04
## ASV2924     -2.753971e-38 -1.550895e-04 -1.615515e-04 -1.682461e-04
## ASV1331      7.975941e-38  4.873848e-04  5.101771e-04  5.332791e-04
## ASV0506     -3.805681e-38 -2.230897e-04 -2.333538e-04 -2.434482e-04
## ASV1514      5.945817e-38  3.675436e-04  3.847974e-04  4.024206e-04
## ASV2144      5.053533e-38  3.054739e-04  3.197218e-04  3.340268e-04
## ASV2265      6.654328e-38  4.081387e-04  4.272914e-04  4.467073e-04
## ASV5156      1.612468e-38  8.860742e-05  9.255359e-05  9.626218e-05
## ASV5534      1.360131e-38  7.188260e-05  7.499353e-05  7.784243e-05
## ASV5747      1.579865e-53 -1.310712e-05 -1.398069e-05 -1.524880e-05
## ASV6657      3.123704e-38  1.836591e-04  1.921654e-04  2.005127e-04
## ASV0658     -3.561795e-38 -2.093071e-04 -2.188964e-04 -2.283969e-04
## ASV0716      8.915064e-39  5.084476e-05  5.311124e-05  5.533140e-05
## ASV1657      1.640683e-38  8.979463e-05  9.373151e-05  9.746815e-05
## ASV1885      1.244497e-39 -4.139239e-06 -4.594229e-06 -5.369904e-06
## ASV2333      7.434581e-38  4.505179e-04  4.714159e-04  4.925752e-04
## ASV3375      2.871737e-38  1.666158e-04  1.741915e-04  1.816506e-04
## ASV4317      2.845844e-38  1.757865e-04  1.840902e-04  1.925377e-04
## ASV9599      1.711521e-53 -1.310715e-05 -1.402936e-05 -1.529819e-05
## ASV0175     -9.990573e-38 -6.033999e-04 -6.312224e-04 -6.594206e-04
## ASV1032      3.091395e-38  1.796002e-04  1.877159e-04  1.957602e-04
## ASV1235      2.238318e-39  4.954083e-06  4.920541e-06  4.718369e-06
## ASV1262      8.755772e-38  5.319365e-04  5.565925e-04  5.816254e-04
## ASV1320      1.948659e-38  1.306268e-04  1.370525e-04  1.438338e-04
## ASV13797     3.306856e-38  1.978041e-04  2.069209e-04  2.160920e-04
## ASV1491      1.460350e-38  9.973086e-05  1.047230e-04  1.099646e-04
## ASV15014     1.711521e-53 -1.310718e-05 -1.404972e-05 -1.531829e-05
## ASV1510      2.481019e-38  1.621122e-04  1.699291e-04  1.781257e-04
## ASV1551     -1.104080e-38 -6.529902e-05 -6.828828e-05 -7.126945e-05
## ASV1919     -3.858843e-39 -1.031412e-05 -1.048917e-05 -1.032337e-05
## ASV2114      1.713869e-38  9.749063e-05  1.018692e-04  1.061456e-04
## ASV21486     1.711521e-53 -1.310720e-05 -1.404449e-05 -1.531095e-05
## ASV2448      4.569306e-38  2.708204e-04  2.832638e-04  2.956731e-04
## ASV2589      2.237777e-38  1.297648e-04  1.356627e-04  1.414718e-04
## ASV2608      3.614853e-38  2.179384e-04  2.280304e-04  2.382199e-04
## ASV2786      2.875533e-38  1.764020e-04  1.845980e-04  1.930162e-04
## ASV2827      3.773243e-38  2.258882e-04  2.363895e-04  2.468584e-04
## ASV2872      3.188979e-38  1.847219e-04  1.930797e-04  2.013194e-04
## ASV3125      3.747887e-38  2.205167e-04  2.305303e-04  2.405584e-04
## ASV3247      4.057156e-38  2.388180e-04  2.496898e-04  2.605462e-04
## ASV3451      1.711521e-53 -1.310728e-05 -1.411386e-05 -1.538314e-05
## ASV3465     -2.469012e-39 -2.896563e-05 -3.065593e-05 -3.271829e-05
## ASV3809      2.403302e-38  1.394288e-04  1.456320e-04  1.518652e-04
## ASV4006      5.058067e-38  2.963538e-04  3.097826e-04  3.231694e-04
## ASV4046      3.617860e-38  2.128680e-04  2.224716e-04  2.321472e-04
## ASV4938     -2.155665e-40 -1.446025e-05 -1.555416e-05 -1.688957e-05
## ASV5435      1.711521e-53 -1.310736e-05 -1.413582e-05 -1.540482e-05
## ASV5605      1.609979e-38  8.615720e-05  8.986042e-05  9.333540e-05
## ASV5635      1.711521e-53 -1.310739e-05 -1.413939e-05 -1.540779e-05
## ASV5743      4.497092e-38  2.681084e-04  2.804050e-04  2.927829e-04
## ASV6627      1.711521e-53 -1.310742e-05 -1.415149e-05 -1.542016e-05
## ASV6785      1.711521e-53 -1.310743e-05 -1.414972e-05 -1.541792e-05
## ASV7368      4.761317e-38  2.943813e-04  3.081117e-04  3.222544e-04
## ASV9118      1.508129e-38  8.128489e-05  8.476024e-05  8.807566e-05
## ASV9135      1.247077e-38  6.390574e-05  6.651118e-05  6.893045e-05
## ASV9435      2.510395e-38  1.406470e-04  1.467916e-04  1.528111e-04
## ASV9671      1.579865e-53 -1.310751e-05 -1.417183e-05 -1.544031e-05
## ASV0387     -5.040080e-38 -2.975041e-04 -3.110156e-04 -3.245793e-04
## ASV0454     -4.962213e-38 -2.956426e-04 -3.091705e-04 -3.227885e-04
## ASV0751     -3.309851e-38 -1.942836e-04 -2.030193e-04 -2.118193e-04
## ASV1081      1.277394e-38  7.827772e-05  8.199831e-05  8.571127e-05
## ASV1332      2.670614e-38  1.614832e-04  1.689449e-04  1.765023e-04
## ASV2659      4.138730e-38  2.563839e-04  2.684167e-04  2.807160e-04
## ASV2979      4.574727e-38  2.680315e-04  2.800825e-04  2.921911e-04
## ASV4184      2.022738e-38  1.094868e-04  1.140920e-04  1.185696e-04
## ASV6198      1.634206e-38  9.451583e-05  9.873643e-05  1.029584e-04
## ASV7454      2.972525e-38  1.750037e-04  1.828959e-04  1.908489e-04
## ASV8198      1.381746e-38  7.149124e-05  7.432603e-05  7.706595e-05
## ASV0855      6.318760e-38  3.897883e-04  4.079820e-04  4.266415e-04
## ASV10092     2.818463e-38  1.657178e-04  1.731768e-04  1.807122e-04
## ASV1532      3.358332e-38  2.117511e-04  2.218808e-04  2.322576e-04
## ASV2553      8.400286e-38  5.137326e-04  5.376842e-04  5.620489e-04
## ASV2741      3.236422e-38  2.055424e-04  2.154672e-04  2.255918e-04
## ASV4095      1.650114e-38  1.107093e-04  1.163213e-04  1.220521e-04
## ASV5295      2.695222e-38  1.530409e-04  1.596999e-04  1.663644e-04
## ASV5787      1.711521e-53 -1.310768e-05 -1.422215e-05 -1.549236e-05
## ASV9455      3.404879e-38  2.012791e-04  2.103333e-04  2.195355e-04
## ASV10879     3.459155e-38  2.093761e-04  2.189884e-04  2.288242e-04
## ASV3997      2.228766e-38  1.448488e-04  1.518686e-04  1.591544e-04
## ASV6760      9.272111e-39  4.296227e-05  4.442269e-05  4.577634e-05
## ASV6990      2.610804e-38  1.522032e-04  1.589534e-04  1.658058e-04
## ASV9560      1.690264e-38  9.469838e-05  9.875317e-05  1.028203e-04
## ASV0220      1.372524e-38  8.277801e-05  8.674619e-05  9.060814e-05
## ASV2518      3.270863e-38  2.014420e-04  2.109046e-04  2.205352e-04
## ASV3615      5.255024e-38  3.179047e-04  3.325277e-04  3.474303e-04
## ASV0075      1.248383e-38  6.953282e-05  7.265708e-05  7.560168e-05
## ASV8070      8.545617e-39  3.991178e-05  4.125582e-05  4.253385e-05
## ASV1658      2.564588e-38  1.509866e-04  1.578059e-04  1.646790e-04
## ASV0773      4.147203e-38  2.438287e-04  2.549555e-04  2.660261e-04
## ASV0799      1.308621e-39  7.829133e-06  8.168069e-06  8.529415e-06
## ASV1839     -9.031958e-39 -4.862145e-05 -5.075421e-05 -5.270749e-05
## ASV0265      3.621898e-38  2.323905e-04  2.437675e-04  2.553494e-04
## ASV3741      1.552936e-38  9.442072e-05  9.874234e-05  1.031866e-04
## ASV0847      5.380913e-38  3.279087e-04  3.432323e-04  3.587160e-04
## ASV1026      5.791672e-38  3.505819e-04  3.668180e-04  3.832451e-04
## ASV1222     -2.006763e-38 -1.122955e-04 -1.169537e-04 -1.217549e-04
## ASV0729      7.995788e-39  4.789632e-05  5.015811e-05  5.237726e-05
## ASV0143     -4.554584e-38 -2.674544e-04 -2.795297e-04 -2.916425e-04
## ASV1328      1.197601e-38  6.842314e-05  7.183630e-05  7.485240e-05
## ASV9078     -8.638951e-39 -6.724196e-05 -7.097660e-05 -7.488422e-05
## ASV0027     -6.129045e-38 -3.822378e-04 -4.004185e-04 -4.189163e-04
## ASV0546     -2.867009e-38 -1.683360e-04 -1.758638e-04 -1.834892e-04
## ASV1136      7.053137e-38  4.274327e-04  4.471782e-04  4.672605e-04
## ASV3081      3.320036e-38  2.037776e-04  2.132480e-04  2.229718e-04
## ASV0531      1.394782e-38  8.983440e-05  9.428129e-05  9.876279e-05
## ASV2525      1.990986e-38  1.174237e-04  1.226898e-04  1.280404e-04
## ASV1083     -8.493520e-39 -4.519635e-05 -4.694064e-05 -4.875326e-05
## ASV0424      1.227119e-38  7.597790e-05  7.952276e-05  8.317674e-05
## ASV0644     -1.733463e-53  8.944656e-06  9.813264e-06  1.067708e-05
## ASV6007      1.492095e-53 -1.316383e-05 -1.433828e-05 -1.561887e-05
## ASV0564      1.585796e-38  1.042190e-04  1.094131e-04  1.147161e-04
## ASV1938      2.007382e-38  1.145547e-04  1.194600e-04  1.244830e-04
## ASV6516     -4.277777e-38 -2.605948e-04 -2.727075e-04 -2.850054e-04
## ASV0503     -5.241223e-38 -3.071616e-04 -3.208252e-04 -3.346931e-04
## ASV6913     -5.220210e-38 -3.050436e-04 -3.188128e-04 -3.325655e-04
## ASV0164     -3.805648e-38 -2.412070e-04 -2.526404e-04 -2.645213e-04
## ASV1576      4.761563e-38  2.896899e-04  3.030789e-04  3.167547e-04
## ASV1725      2.125365e-38  1.391690e-04  1.461473e-04  1.532099e-04
## ASV4501      2.183865e-38  1.238216e-04  1.290805e-04  1.344576e-04
## ASV10678    -4.213446e-38 -2.544687e-04 -2.662559e-04 -2.781491e-04
## ASV0944      3.325204e-38  2.108598e-04  2.208963e-04  2.312814e-04
## ASV2292      5.476757e-38  3.304445e-04  3.456151e-04  3.610502e-04
## ASV1090      3.521312e-38  2.161516e-04  2.261170e-04  2.364122e-04
## ASV9117     -1.897843e-38 -1.065290e-04 -1.109518e-04 -1.155261e-04
## ASV0285     -1.878554e-38 -1.260999e-04 -1.325612e-04 -1.391144e-04
## ASV0463     -3.568047e-38 -2.117619e-04 -2.212069e-04 -2.309027e-04
## ASV3199      3.134678e-38  1.829364e-04  1.909989e-04  1.992294e-04
## ASV0150     -1.103024e-38 -7.374472e-05 -7.743546e-05 -8.124885e-05
## ASV6583     -1.892061e-38 -1.089354e-04 -1.135044e-04 -1.183361e-04
## ASV0392      2.792587e-38  1.727913e-04  1.807996e-04  1.890945e-04
## ASV14007    -3.459648e-38 -2.094126e-04 -2.190062e-04 -2.288122e-04
## ASV0177     -1.987566e-38 -1.160522e-04 -1.211068e-04 -1.263264e-04
## ASV6448     -1.213724e-38 -8.793902e-05 -9.268934e-05 -9.754719e-05
## ASV5399     -3.657760e-39 -3.557555e-05 -3.782245e-05 -4.017126e-05
## ASV0277     -6.815782e-39 -4.295861e-05 -4.500913e-05 -4.711188e-05
## ASV2599      1.458945e-38  7.306914e-05  7.601113e-05  7.867132e-05
## ASV13465    -1.217653e-38 -5.884158e-05 -6.109988e-05 -6.310488e-05
## ASV2412      1.749340e-38  1.081579e-04  1.132039e-04  1.183881e-04
## ASV0423      3.278161e-38  2.125327e-04  2.228266e-04  2.335446e-04
## ASV5187      2.373825e-38  1.335361e-04  1.391252e-04  1.448774e-04
## ASV0701     -8.100065e-38 -4.975814e-04 -5.210554e-04 -5.447622e-04
## ASV4248      1.808802e-38  1.181978e-04  1.241834e-04  1.301695e-04
## ASV0519      3.303489e-38  2.087612e-04  2.187688e-04  2.290025e-04
## ASV0764      4.817093e-39  3.545405e-05  3.731153e-05  3.929720e-05
## ASV5385     -4.230483e-38 -2.616983e-04 -2.740295e-04 -2.865898e-04
## ASV3021     -2.693519e-38 -1.488176e-04 -1.552319e-04 -1.614949e-04
## ASV4119     -1.533501e-38 -8.315562e-05 -8.659678e-05 -9.001134e-05
## ASV2534      7.307864e-39  4.298602e-05  4.476134e-05  4.671637e-05
## ASV1061      2.986485e-38  2.000454e-04  2.099752e-04  2.203747e-04
## ASV0670      4.508419e-38  2.789715e-04  2.921377e-04  3.055315e-04
## ASV1384      1.797613e-38  1.204297e-04  1.264811e-04  1.327217e-04
## ASV1981      4.151370e-38  2.596336e-04  2.720296e-04  2.846304e-04
## ASV9632     -1.643466e-38 -8.702391e-05 -9.039257e-05 -9.384559e-05
## ASV4564      1.012326e-38  6.395345e-05  6.702284e-05  7.016001e-05
## ASV5289     -9.454109e-39 -5.792748e-05 -6.071311e-05 -6.346663e-05
## ASV0516      8.568451e-38  5.289000e-04  5.537500e-04  5.790678e-04
## ASV1463     -3.200516e-38 -1.909489e-04 -1.997050e-04 -2.085029e-04
## ASV0969      1.511912e-38  8.888331e-05  9.288258e-05  9.690285e-05
## ASV1113     -3.998190e-38 -2.464676e-04 -2.579778e-04 -2.697664e-04
## ASV1234      4.394788e-40 -8.248313e-06 -9.121631e-06 -1.009317e-05
## ASV3814      8.595295e-39  3.828842e-05  3.932805e-05  4.042528e-05
## ASV1000      4.186067e-38  2.521918e-04  2.638128e-04  2.755640e-04
## ASV0079     -2.429104e-39 -2.196674e-05 -2.324387e-05 -2.465783e-05
## ASV0145      1.504519e-38  8.596624e-05  8.964981e-05  9.342236e-05
## ASV0457     -5.317495e-38 -3.176915e-04 -3.322841e-04 -3.469586e-04
## ASV1485      1.628540e-38  1.032176e-04  1.081614e-04  1.132510e-04
## ASV0535     -1.188618e-38 -7.024470e-05 -7.324725e-05 -7.646266e-05
## ASV0259     -3.416494e-38 -2.077307e-04 -2.174331e-04 -2.272085e-04
## ASV0570      1.362727e-39  1.500469e-05  1.593981e-05  1.699075e-05
## ASV0906      4.485730e-38  2.703818e-04  2.827877e-04  2.953964e-04
## ASV1748     -2.368600e-38 -1.585193e-04 -1.664518e-04 -1.746533e-04
## ASV5520     -1.289010e-38 -9.342880e-05 -9.836258e-05 -1.035271e-04
## ASV2288     -5.252116e-38 -3.100395e-04 -3.243658e-04 -3.384920e-04
## ASV1887     -7.553707e-39 -5.789006e-05 -6.114277e-05 -6.446759e-05
## ASV0374     -1.691508e-38 -9.861602e-05 -1.029832e-04 -1.074102e-04
## ASV0823      5.133624e-38  3.056316e-04  3.194256e-04  3.334919e-04
## ASV0717      2.460724e-38  1.532375e-04  1.604718e-04  1.678784e-04
## ASV0431      1.787548e-38  1.059518e-04  1.108300e-04  1.156763e-04
## ASV1030      6.998089e-38  4.429723e-04  4.641764e-04  4.859491e-04
## ASV1082     -1.049765e-38 -6.481477e-05 -6.787919e-05 -7.098440e-05
## ASV2684      4.864533e-39  4.034361e-05  4.269862e-05  4.513582e-05
## ASV0051      6.303534e-38  3.940649e-04  4.126428e-04  4.317829e-04
## ASV0513      2.399094e-39  1.640242e-05  1.732493e-05  1.819872e-05
## ASV0581      8.083178e-38  5.000207e-04  5.236258e-04  5.476298e-04
## ASV7282      1.252159e-38  8.709804e-05  9.148923e-05  9.617276e-05
## ASV3009     -4.453000e-38 -2.742458e-04 -2.871137e-04 -3.002152e-04
## ASV2106     -2.406350e-38 -1.398568e-04 -1.460287e-04 -1.522925e-04
## ASV1012      1.317516e-38  8.750649e-05  9.187733e-05  9.637869e-05
## ASV0921     -1.329964e-39 -6.037004e-06 -6.208335e-06 -6.383627e-06
## ASV0010     -6.226606e-38 -3.907565e-04 -4.093177e-04 -4.283532e-04
## ASV1178      7.543074e-40  7.830310e-06  8.384244e-06  8.911648e-06
## ASV2848     -3.520821e-38 -2.107973e-04 -2.203596e-04 -2.301359e-04
## ASV0586      9.140052e-38  5.671037e-04  5.938730e-04  6.211864e-04
## ASV4225      1.525470e-39  1.592771e-05  1.741642e-05  1.849365e-05
## ASV2156     -3.821022e-38 -2.363908e-04 -2.475686e-04 -2.589250e-04
## ASV9778     -2.456204e-38 -1.492589e-04 -1.561822e-04 -1.632028e-04
## ASV0493     -5.482259e-38 -3.307638e-04 -3.458835e-04 -3.613355e-04
## ASV3770      1.078128e-38  6.123855e-05  6.361122e-05  6.628224e-05
## ASV0470      6.543959e-38  4.029777e-04  4.217837e-04  4.410323e-04
## ASV0262     -2.508091e-38 -1.669824e-04 -1.753633e-04 -1.839821e-04
## ASV0998      3.970297e-38  2.469361e-04  2.585783e-04  2.705038e-04
## ASV7708     -1.132383e-38 -6.771595e-05 -7.070989e-05 -7.383282e-05
## ASV0453     -1.537160e-39 -8.597337e-06 -8.917851e-06 -9.295299e-06
## ASV0044      8.214650e-38  5.077369e-04  5.313921e-04  5.557378e-04
## ASV5490      1.344841e-38  7.981807e-05  8.346625e-05  8.711585e-05
## ASV2638      2.997621e-39  2.140662e-05  2.263759e-05  2.379406e-05
## ASV0829     -8.594898e-39 -4.591937e-05 -4.775810e-05 -4.960997e-05
## ASV0601      1.439565e-38  9.319621e-05  9.767368e-05  1.023637e-04
## ASV0234      3.600485e-38  2.204087e-04  2.307790e-04  2.412414e-04
## ASV0133      4.698288e-38  2.912832e-04  3.049256e-04  3.189431e-04
## ASV0323      4.881431e-38  3.084750e-04  3.231806e-04  3.383393e-04
## ASV0854     -4.381738e-39 -2.368470e-05 -2.470363e-05 -2.566212e-05
## ASV0110      6.238672e-38  3.906244e-04  4.090704e-04  4.280694e-04
## ASV0816      3.647516e-39  2.131369e-05  2.224160e-05  2.320239e-05
## ASV1031     -1.048331e-38 -6.162478e-05 -6.426807e-05 -6.707537e-05
## ASV0144     -2.607409e-38 -1.594319e-04 -1.668913e-04 -1.744508e-04
## ASV0020     -1.028366e-38 -7.229652e-05 -7.599925e-05 -7.993702e-05
## ASV0962     -2.122252e-38 -1.304761e-04 -1.365708e-04 -1.427899e-04
## ASV0794      3.963597e-38  2.565265e-04  2.690079e-04  2.818910e-04
## ASV7117     -2.141849e-38 -1.330556e-04 -1.391574e-04 -1.455696e-04
## ASV1008     -1.467436e-38 -9.458305e-05 -9.914547e-05 -1.038852e-04
## ASV0096      6.715224e-38  4.207864e-04  4.406090e-04  4.610885e-04
## ASV0128     -3.897035e-38 -2.513356e-04 -2.634956e-04 -2.761086e-04
## ASV5232      3.027018e-38  1.905172e-04  1.997426e-04  2.090524e-04
## ASV0031      2.765044e-39  1.238311e-05  1.285817e-05  1.320685e-05
## ASV1744     -4.501257e-39 -2.899387e-05 -3.030765e-05 -3.177946e-05
## ASV0289      3.767706e-38  2.343810e-04  2.453711e-04  2.567016e-04
## ASV7413     -6.380907e-39 -5.167536e-05 -5.465581e-05 -5.774071e-05
## ASV0822     -4.716991e-38 -2.831309e-04 -2.960276e-04 -3.091723e-04
## ASV8111     -4.169062e-38 -2.397472e-04 -2.505946e-04 -2.612070e-04
## ASV0687      2.759518e-38  1.756401e-04  1.841272e-04  1.928026e-04
## ASV0112      1.120695e-38  5.612154e-05  5.858686e-05  6.059212e-05
## ASV0987      2.225322e-38  1.415524e-04  1.483957e-04  1.553982e-04
## ASV5332     -1.411156e-38 -7.879867e-05 -8.192982e-05 -8.530049e-05
## ASV1129     -2.973524e-38 -1.854159e-04 -1.941085e-04 -2.030984e-04
## ASV1274     -9.717767e-39 -6.083293e-05 -6.366813e-05 -6.662352e-05
## ASV0119      5.478743e-38  3.428676e-04  3.589964e-04  3.756585e-04
## ASV0890      1.342358e-38  8.665964e-05  9.076379e-05  9.510379e-05
## ASV0848      7.928293e-38  4.918982e-04  5.150680e-04  5.387547e-04
## ASV5944     -4.378588e-38 -2.575337e-04 -2.694943e-04 -2.811856e-04
## ASV19741    -4.182093e-38 -2.578389e-04 -2.697671e-04 -2.820947e-04
## ASV0504     -4.911402e-38 -2.959993e-04 -3.094858e-04 -3.232954e-04
## ASV2146     -3.209636e-38 -1.942896e-04 -2.029916e-04 -2.121191e-04
## ASV0089     -2.517405e-38 -1.614460e-04 -1.690786e-04 -1.771139e-04
## ASV2301     -2.729800e-38 -1.710809e-04 -1.791937e-04 -1.875238e-04
## ASV2982      7.442762e-39  5.056217e-05  5.362165e-05  5.626445e-05
## ASV0891     -3.502569e-38 -2.167956e-04 -2.269017e-04 -2.373137e-04
## ASV0093      5.691894e-38  3.519390e-04  3.684341e-04  3.853249e-04
## ASV0042      2.755813e-38  1.667474e-04  1.745376e-04  1.823540e-04
## ASV0980      3.856416e-38  2.338034e-04  2.445295e-04  2.555019e-04
## ASV0069     -8.801954e-39 -5.872488e-05 -6.156334e-05 -6.460488e-05
## ASV1364     -6.623203e-39 -4.177961e-05 -4.363625e-05 -4.568022e-05
## ASV0524     -1.027609e-38 -6.777714e-05 -7.104838e-05 -7.452374e-05
## ASV0435      7.471152e-38  4.651475e-04  4.870957e-04  5.095828e-04
## ASV0517     -3.056280e-38 -1.889391e-04 -1.978598e-04 -2.069251e-04
## ASV3167     -1.268383e-38 -8.125344e-05 -8.527669e-05 -8.931771e-05
## ASV4280     -4.995943e-39 -3.421541e-05 -3.571563e-05 -3.752792e-05
## ASV1158      1.708228e-38  1.129040e-04  1.185896e-04  1.243595e-04
## ASV2214      1.425520e-38  8.824133e-05  9.223648e-05  9.649854e-05
## ASV0544     -1.668881e-38 -1.043649e-04 -1.093905e-04 -1.144643e-04
## ASV5326     -3.187033e-39 -1.899559e-05 -1.989385e-05 -2.076995e-05
## ASV3765     -4.494004e-38 -2.717373e-04 -2.844555e-04 -2.971753e-04
## ASV4646      6.121052e-40 -5.882625e-06 -6.528955e-06 -7.287419e-06
## ASV0090      5.184869e-39  2.753818e-05  2.870504e-05  2.979222e-05
## ASV3680      4.341329e-38  2.571004e-04  2.686152e-04  2.803629e-04
## ASV0111      7.565369e-39  4.281703e-05  4.470479e-05  4.655366e-05
## ASV0768      2.548455e-38  1.590531e-04  1.666524e-04  1.743689e-04
## ASV4862     -1.739272e-39 -9.497676e-06 -9.829045e-06 -1.021573e-05
## ASV1742     -3.551583e-38 -2.109998e-04 -2.204405e-04 -2.301326e-04
## ASV3701     -5.809251e-39 -3.709101e-05 -3.857695e-05 -4.041583e-05
## ASV2386     -2.065815e-38 -1.266135e-04 -1.326265e-04 -1.386416e-04
## ASV0375     -4.939936e-38 -2.967005e-04 -3.102367e-04 -3.240284e-04
## ASV2796      1.334889e-38  7.937735e-05  8.285278e-05  8.650780e-05
## ASV1369      3.408110e-38  2.050180e-04  2.143460e-04  2.239043e-04
## ASV10272    -3.040027e-38 -1.853784e-04 -1.940641e-04 -2.028212e-04
## ASV10354    -3.040027e-38 -1.853783e-04 -1.940495e-04 -2.028057e-04
## ASV1067     -2.322149e-39 -1.569491e-05 -1.648584e-05 -1.730845e-05
## ASV1900      6.222341e-38  3.878496e-04  4.061452e-04  4.249160e-04
## ASV4079     -1.036164e-38 -6.630667e-05 -6.955798e-05 -7.285158e-05
## ASV4149      4.409513e-38  2.617254e-04  2.735282e-04  2.855183e-04
## ASV5140     -3.040027e-38 -1.853784e-04 -1.940348e-04 -2.027902e-04
## ASV10782    -1.804520e-39 -8.662818e-06 -8.961098e-06 -9.241919e-06
## ASV4273     -7.479188e-39 -4.281040e-05 -4.472787e-05 -4.659850e-05
## ASV8121      2.868455e-38  1.786944e-04  1.870621e-04  1.957097e-04
## ASV8438     -3.040027e-38 -1.853784e-04 -1.940216e-04 -2.027764e-04
## ASV9390     -3.040027e-38 -1.853784e-04 -1.940070e-04 -2.027609e-04
## ASV1340      4.093787e-38  2.564319e-04  2.685811e-04  2.810551e-04
## ASV2650     -4.569051e-38 -2.756203e-04 -2.882832e-04 -3.011406e-04
## ASV4674      2.278712e-38  1.409291e-04  1.475009e-04  1.542603e-04
## ASV10492    -1.805289e-39 -1.211485e-05 -1.265983e-05 -1.328681e-05
## ASV11430    -3.040027e-38 -1.853783e-04 -1.939853e-04 -2.027379e-04
## ASV12135    -3.040027e-38 -1.853783e-04 -1.939708e-04 -2.027224e-04
## ASV14970    -3.040027e-38 -1.853783e-04 -1.939563e-04 -2.027069e-04
## ASV1954      3.415967e-38  2.112806e-04  2.211984e-04  2.313350e-04
## ASV2613      5.369877e-38  3.303344e-04  3.457179e-04  3.614749e-04
## ASV2757      2.209087e-38  1.309910e-04  1.369119e-04  1.429090e-04
## ASV2909     -3.113541e-38 -1.933122e-04 -2.024786e-04 -2.117968e-04
## ASV2954     -6.464487e-39 -3.740765e-05 -3.910658e-05 -4.076421e-05
## ASV2969      2.886375e-38  1.821552e-04  1.908583e-04  1.997947e-04
## ASV3410      5.666365e-39  3.896485e-05  4.088103e-05  4.295818e-05
## ASV3575      1.564300e-38  9.706354e-05  1.015692e-04  1.062495e-04
## ASV4275      3.536200e-38  2.109238e-04  2.205280e-04  2.302447e-04
## ASV4652      5.307887e-39  3.673501e-05  3.854750e-05  4.051137e-05
## ASV4761      3.526201e-38  2.106995e-04  2.203063e-04  2.300270e-04
## ASV6003      2.522470e-38  1.622834e-04  1.700900e-04  1.782131e-04
## ASV6110     -3.040027e-38 -1.853784e-04 -1.939872e-04 -2.027404e-04
## ASV7427      1.959506e-38  1.212076e-04  1.268232e-04  1.326394e-04
## ASV8092     -3.040027e-38 -1.853784e-04 -1.939778e-04 -2.027304e-04
## ASV8169     -3.040027e-38 -1.853783e-04 -1.939632e-04 -2.027149e-04
## ASV9693      1.301781e-38  8.097959e-05  8.477749e-05  8.868664e-05
## ASV10913     1.384640e-38  8.908529e-05  9.336456e-05  9.782074e-05
## ASV1979     -5.120549e-39 -3.032805e-05 -3.167850e-05 -3.306300e-05
## ASV3772      3.780361e-38  2.300183e-04  2.406049e-04  2.514483e-04
## ASV0113      7.657695e-39  4.353722e-05  4.552389e-05  4.741470e-05
## ASV1800     -2.968267e-39 -1.971279e-05 -2.061949e-05 -2.161922e-05
## ASV2335     -4.067643e-38 -2.341268e-04 -2.447369e-04 -2.551104e-04
## ASV0692      1.261345e-38  7.973656e-05  8.348993e-05  8.739958e-05
## ASV1120      1.632735e-38  1.006886e-04  1.054214e-04  1.102378e-04
## ASV1434     -8.658433e-38 -5.340603e-04 -5.591700e-04 -5.847326e-04
## ASV0076     -9.294980e-39 -6.173762e-05 -6.469961e-05 -6.788244e-05
## ASV0361      6.463148e-38  4.042469e-04  4.232798e-04  4.429121e-04
## ASV2231     -2.017176e-38 -1.352460e-04 -1.419476e-04 -1.489911e-04
## ASV2018     -8.523333e-40 -1.088400e-05 -1.141925e-05 -1.223543e-05
## ASV1529      5.329279e-38  3.352546e-04  3.512153e-04  3.676064e-04
## ASV0841     -3.123463e-39 -1.707194e-05 -1.777216e-05 -1.847247e-05
## ASV2556     -3.299648e-38 -2.019538e-04 -2.113311e-04 -2.209063e-04
## ASV2777      4.323659e-38  2.559220e-04  2.673948e-04  2.790802e-04
## ASV0355      3.338025e-38  2.094970e-04  2.193381e-04  2.295529e-04
## ASV5169     -4.675239e-38 -2.868418e-04 -3.002743e-04 -3.139183e-04
## ASV3091      2.191844e-38  1.403325e-04  1.470333e-04  1.540195e-04
## ASV2435      3.323790e-38  2.025344e-04  2.120003e-04  2.215573e-04
## ASV6822     -2.143986e-38 -1.308626e-04 -1.368838e-04 -1.430648e-04
## ASV12605    -5.095941e-38 -3.131735e-04 -3.278025e-04 -3.427225e-04
## ASV0286     -3.410740e-38 -2.095438e-04 -2.192488e-04 -2.292473e-04
## ASV0074     -4.693796e-40 -1.225887e-05 -1.304667e-05 -1.412293e-05
## ASV2485     -2.061041e-39 -8.558711e-06 -9.067719e-06 -9.282316e-06
## ASV1233     -6.447314e-38 -4.001118e-04 -4.189016e-04 -4.381870e-04
## ASV0356     -3.150438e-38 -1.914448e-04 -2.002177e-04 -2.092372e-04
## ASV2918     -3.966520e-38 -2.318929e-04 -2.426145e-04 -2.530675e-04
## ASV1427      3.429366e-40 -1.453952e-07 -2.040126e-07 -3.313699e-07
## ASV1409      3.677986e-38  2.341008e-04  2.452343e-04  2.568207e-04
## ASV0770      1.280859e-38  7.232359e-05  7.556794e-05  7.866848e-05
## ASV1403     -4.569919e-38 -2.811551e-04 -2.942369e-04 -3.076506e-04
## ASV0314     -2.459058e-38 -1.525190e-04 -1.596627e-04 -1.669987e-04
## ASV0187      1.384455e-39  3.483776e-06  3.439930e-06  3.349875e-06
## ASV0313     -3.380405e-38 -2.041821e-04 -2.136679e-04 -2.232177e-04
## ASV1087      5.713278e-38  3.559093e-04  3.725865e-04  3.897994e-04
## ASV1970      3.456843e-39  1.893373e-05  1.978844e-05  2.057038e-05
## ASV0754      4.598408e-38  2.863718e-04  2.998210e-04  3.136700e-04
## ASV3775     -3.094402e-38 -1.950671e-04 -2.043284e-04 -2.138856e-04
## ASV0132      1.337278e-38  8.005818e-05  8.379955e-05  8.750100e-05
## ASV2329     -7.242003e-39 -5.533575e-05 -5.828220e-05 -6.145910e-05
## ASV0561      4.041917e-38  2.448212e-04  2.561990e-04  2.676759e-04
## ASV0130     -4.822305e-38 -2.993822e-04 -3.135068e-04 -3.279280e-04
## ASV0226      5.486676e-38  3.397569e-04  3.556913e-04  3.720157e-04
## ASV12648    -3.957854e-38 -2.414511e-04 -2.524970e-04 -2.639267e-04
## ASV0204      5.471322e-38  3.387163e-04  3.545740e-04  3.708416e-04
## ASV0767      1.032003e-38  5.672477e-05  5.924659e-05  6.159409e-05
## ASV0335     -2.971859e-38 -1.854707e-04 -1.941800e-04 -2.031592e-04
## ASV5901     -9.805845e-39 -5.565138e-05 -5.807102e-05 -6.049402e-05
## ASV0596     -1.273018e-38 -7.176431e-05 -7.496688e-05 -7.805035e-05
## ASV9271      9.664956e-39  6.875895e-05  7.242608e-05  7.618091e-05
## ASV0904      4.785330e-38  2.983666e-04  3.125018e-04  3.269509e-04
## ASV15270    -1.158588e-38 -7.740359e-05 -8.142323e-05 -8.540665e-05
## ASV0990     -1.337005e-38 -8.619886e-05 -9.029033e-05 -9.460988e-05
## ASV0155     -2.928215e-38 -1.797391e-04 -1.881538e-04 -1.967084e-04
## ASV0086     -3.913130e-40 -8.698698e-07 -9.162412e-07 -8.794055e-07
## ASV2581     -2.542304e-39 -1.112718e-05 -1.161473e-05 -1.190495e-05
## ASV1579     -3.314543e-38 -2.118830e-04 -2.219974e-04 -2.325250e-04
## ASV7730      1.141014e-53 -8.154909e-06 -8.838235e-06 -9.622499e-06
## ASV0897      1.389932e-38  8.681430e-05  9.097490e-05  9.518828e-05
## ASV1975      6.621688e-38  4.084776e-04  4.276123e-04  4.471693e-04
## ASV0759     -1.859264e-39 -9.827593e-06 -1.028934e-05 -1.068082e-05
## ASV3082     -3.988679e-38 -2.478917e-04 -2.595229e-04 -2.714834e-04
## ASV3195     -6.872618e-38 -4.324226e-04 -4.528125e-04 -4.739547e-04
## ASV0427      3.594451e-38  2.268645e-04  2.376343e-04  2.487622e-04
## ASV2674      7.922651e-39  4.704968e-05  4.924716e-05  5.139118e-05
## ASV1500      1.145959e-38  7.074228e-05  7.375281e-05  7.713873e-05
## ASV0102     -4.090128e-38 -2.595440e-04 -2.718991e-04 -2.847036e-04
## ASV1217     -1.111911e-38 -6.551469e-05 -6.863743e-05 -7.161538e-05
## ASV4998     -4.406020e-39 -2.726888e-05 -2.855598e-05 -2.986400e-05
## ASV2890      6.081302e-38  3.709956e-04  3.881982e-04  4.057367e-04
## ASV0672     -2.582478e-38 -1.610085e-04 -1.685837e-04 -1.763805e-04
## ASV6960     -2.210618e-38 -1.451870e-04 -1.524451e-04 -1.598258e-04
## ASV0821      3.996265e-38  2.407687e-04  2.521389e-04  2.633843e-04
## ASV1995     -3.687907e-38 -2.298565e-04 -2.406833e-04 -2.518063e-04
## ASV0211     -1.964535e-38 -1.291309e-04 -1.353524e-04 -1.419396e-04
## ASV0364      2.143964e-38  1.342848e-04  1.405344e-04  1.470656e-04
## ASV3616      4.872433e-38  2.884392e-04  3.017950e-04  3.149867e-04
## ASV1996      5.286083e-38  3.255493e-04  3.406247e-04  3.561859e-04
## ASV1881     -8.359372e-39 -5.277218e-05 -5.530003e-05 -5.789143e-05
## ASV1089      5.144287e-38  3.171041e-04  3.320706e-04  3.472371e-04
## ASV1450     -1.084267e-38 -6.514095e-05 -6.822333e-05 -7.125151e-05
## ASV4643     -2.945056e-38 -1.812655e-04 -1.896623e-04 -1.983074e-04
## ASV3458      1.397648e-38  8.869901e-05  9.345164e-05  9.781187e-05
## ASV2543     -1.230170e-38 -7.932820e-05 -8.312448e-05 -8.710170e-05
## ASV3306     -1.413873e-38 -8.964464e-05 -9.443131e-05 -9.883433e-05
## ASV0218     -2.834117e-38 -1.766800e-04 -1.849562e-04 -1.935124e-04
## ASV3727      1.812312e-38  1.180776e-04  1.237889e-04  1.297695e-04
## ASV4394     -1.988477e-38 -1.275681e-04 -1.336507e-04 -1.400068e-04
## ASV2636     -6.278898e-41  9.435448e-06  1.016854e-05  1.114030e-05
## ASV5116      5.329684e-39  3.207555e-05  3.345365e-05  3.493960e-05
## ASV1394     -5.050616e-38 -3.144608e-04 -3.292468e-04 -3.444505e-04
## ASV0656     -5.034807e-38 -3.087319e-04 -3.230980e-04 -3.377737e-04
## ASV0475      7.493342e-38  4.686907e-04  4.907821e-04  5.135501e-04
## ASV1042      1.880650e-38  1.170809e-04  1.225615e-04  1.282147e-04
## ASV1199     -3.841110e-38 -2.418514e-04 -2.532173e-04 -2.650490e-04
## ASV12962    -2.846091e-39 -1.629290e-05 -1.698912e-05 -1.770156e-05
## ASV0853      3.545569e-38  2.192662e-04  2.296990e-04  2.402064e-04
## ASV5069     -5.753133e-39 -4.901481e-05 -5.189245e-05 -5.492076e-05
## ASV7825     -2.194296e-38 -1.367065e-04 -1.432635e-04 -1.498799e-04
## ASV0339      2.462269e-38  1.533382e-04  1.604879e-04  1.679017e-04
## ASV2965      2.135155e-38  1.334748e-04  1.397661e-04  1.462438e-04
## ASV2347     -2.934600e-38 -1.776150e-04 -1.858545e-04 -1.941794e-04
## ASV0541      1.162348e-38  7.754091e-05  8.122004e-05  8.522479e-05
## ASV0369      3.376901e-38  2.080349e-04  2.177112e-04  2.276479e-04
## ASV0171      1.690821e-38  1.051994e-04  1.101283e-04  1.152208e-04
## ASV2235      4.275898e-38  2.534551e-04  2.648541e-04  2.764562e-04
## ASV5809     -3.870990e-38 -2.372111e-04 -2.482279e-04 -2.594902e-04
## ASV1267      4.844768e-38  2.986127e-04  3.126118e-04  3.268836e-04
## ASV0207     -5.238866e-38 -3.216329e-04 -3.366657e-04 -3.519695e-04
## ASV3126     -6.051393e-38 -3.798356e-04 -3.977731e-04 -4.162918e-04
## ASV0183     -6.769651e-38 -4.191657e-04 -4.387559e-04 -4.588923e-04
## ASV1792      2.376564e-38  1.438487e-04  1.504710e-04  1.572035e-04
## ASV2001     -5.869279e-38 -3.693294e-04 -3.867222e-04 -4.047813e-04
## ASV5732     -5.870030e-38 -3.635224e-04 -3.805740e-04 -3.980390e-04
## ASV2857     -3.676217e-38 -2.301697e-04 -2.409710e-04 -2.521649e-04
## ASV1052     -2.755478e-38 -1.680169e-04 -1.758265e-04 -1.837809e-04
## ASV3226     -1.718414e-38 -1.069126e-04 -1.118537e-04 -1.170112e-04
## ASV3766     -6.278329e-39 -3.945034e-05 -4.132002e-05 -4.324801e-05
## ASV0982     -1.781361e-38 -1.151872e-04 -1.206768e-04 -1.264660e-04
## ASV0489      7.090036e-40 -2.052890e-06 -2.306663e-06 -2.739450e-06
## ASV3990     -6.309199e-38 -3.950771e-04 -4.136828e-04 -4.328984e-04
## ASV0433     -3.856348e-38 -2.350142e-04 -2.459192e-04 -2.570052e-04
## ASV0684     -1.561629e-38 -1.009865e-04 -1.057621e-04 -1.108444e-04
## ASV0063     -4.478383e-38 -2.777049e-04 -2.906906e-04 -3.040404e-04
## ASV1399      8.942694e-39  4.796969e-05  5.004615e-05  5.196131e-05
## ASV3093     -7.475139e-38 -4.705690e-04 -4.927970e-04 -5.158185e-04
## ASV1771      8.795778e-39  5.751478e-05  6.027644e-05  6.319696e-05
## ASV7910     -4.035016e-38 -2.383909e-04 -2.494335e-04 -2.603130e-04
## ASV3718     -5.067986e-38 -3.152380e-04 -3.301011e-04 -3.453263e-04
## ASV0039     -3.880856e-38 -2.477855e-04 -2.594758e-04 -2.717563e-04
## ASV6469     -8.338458e-38 -5.153860e-04 -5.396820e-04 -5.643990e-04
## ASV8186     -5.613175e-38 -3.489533e-04 -3.653773e-04 -3.822199e-04
## ASV1091     -5.390966e-39 -3.542876e-05 -3.710904e-05 -3.891667e-05
## ASV16930    -6.841221e-38 -4.265204e-04 -4.466409e-04 -4.672910e-04
## ASV7234     -5.131346e-38 -3.195124e-04 -3.344869e-04 -3.499293e-04
## ASV1560     -5.975621e-39 -3.830775e-05 -4.014276e-05 -4.205193e-05
## ASV2968      9.829224e-39  6.427221e-05  6.742167e-05  7.069260e-05
## ASV3824     -5.321479e-38 -3.286471e-04 -3.441036e-04 -3.598567e-04
## ASV0442     -3.260640e-38 -2.046845e-04 -2.143548e-04 -2.243371e-04
## ASV0677     -2.648929e-38 -1.567459e-04 -1.637420e-04 -1.708906e-04
## ASV4796     -3.589275e-38 -2.190138e-04 -2.291301e-04 -2.394978e-04
## ASV2206     -5.581201e-38 -3.486656e-04 -3.650319e-04 -3.819448e-04
## ASV2884      1.109874e-38  6.948577e-05  7.272135e-05  7.609651e-05
## ASV0482     -2.012834e-38 -1.265144e-04 -1.324383e-04 -1.386140e-04
## ASV1273      4.594520e-38  2.894120e-04  3.031242e-04  3.172705e-04
## ASV1910      6.965553e-39  3.891661e-05  4.054824e-05  4.219662e-05
## ASV0105      3.648005e-38  2.200631e-04  2.302765e-04  2.405491e-04
## ASV0149      3.739781e-38  2.326461e-04  2.435819e-04  2.548159e-04
## ASV5007     -5.791031e-38 -3.622472e-04 -3.793030e-04 -3.968999e-04
## ASV0757      4.985611e-38  3.127393e-04  3.274737e-04  3.427146e-04
## ASV11952    -4.245817e-38 -2.599075e-04 -2.720462e-04 -2.843750e-04
## ASV4102      3.296684e-38  2.064257e-04  2.162008e-04  2.262385e-04
## ASV1034      4.236239e-38  2.610139e-04  2.731209e-04  2.855940e-04
## ASV0753      3.121908e-38  1.935776e-04  2.027011e-04  2.120227e-04
## ASV2323      1.854846e-38  1.172369e-04  1.227267e-04  1.284798e-04
## ASV0881     -1.514337e-38 -9.169850e-05 -9.605742e-05 -1.003564e-04
## ASV3730     -3.925081e-38 -2.431407e-04 -2.545092e-04 -2.661938e-04
## ASV2685     -1.573644e-38 -9.355514e-05 -9.790698e-05 -1.022003e-04
## ASV3826     -7.386742e-39 -4.607649e-05 -4.815169e-05 -5.038190e-05
## ASV0689      2.754763e-39  2.087786e-05  2.196614e-05  2.316983e-05
## ASV4315     -5.081773e-38 -3.181240e-04 -3.330566e-04 -3.485226e-04
## ASV1239      2.647892e-38  1.548325e-04  1.617174e-04  1.686952e-04
## ASV3147     -8.147667e-39 -5.273082e-05 -5.522120e-05 -5.787259e-05
## ASV3454     -3.840625e-38 -2.376719e-04 -2.487590e-04 -2.601704e-04
## ASV4411     -2.207363e-38 -1.411304e-04 -1.478168e-04 -1.548353e-04
## ASV3007      4.665056e-38  2.846305e-04  2.978846e-04  3.113380e-04
## ASV6151     -3.826260e-38 -2.311648e-04 -2.417682e-04 -2.525848e-04
## ASV0834      3.834181e-38  2.417599e-04  2.531507e-04  2.649866e-04
## ASV1231      5.598695e-38  3.476271e-04  3.638867e-04  3.806329e-04
## ASV0643      4.726539e-38  2.931483e-04  3.068233e-04  3.209251e-04
## ASV0924      1.319149e-39  8.371462e-06  8.880343e-06  9.289912e-06
## ASV3238     -2.383924e-38 -1.450538e-04 -1.518144e-04 -1.586485e-04
## ASV1276     -2.750582e-38 -1.704933e-04 -1.783989e-04 -1.865927e-04
## ASV5503     -7.483618e-38 -4.610935e-04 -4.827858e-04 -5.048215e-04
## ASV0404      2.947214e-38  1.853304e-04  1.940365e-04  2.030864e-04
## ASV3430      2.721993e-39  2.718958e-05  2.858903e-05  3.042962e-05
## ASV5401     -3.145597e-38 -1.968745e-04 -2.060564e-04 -2.156208e-04
## ASV3426     -6.787422e-38 -4.199501e-04 -4.396863e-04 -4.598477e-04
## ASV0777      4.032554e-38  2.498649e-04  2.616390e-04  2.736540e-04
## ASV11093    -2.707956e-38 -1.680200e-04 -1.758582e-04 -1.839485e-04
## ASV2170     -2.409193e-38 -1.464803e-04 -1.533084e-04 -1.602061e-04
## ASV3861      2.234765e-38  1.331626e-04  1.392471e-04  1.453692e-04
## ASV1723     -3.913085e-38 -2.442268e-04 -2.556668e-04 -2.674976e-04
## ASV2460     -2.193632e-38 -1.381850e-04 -1.447009e-04 -1.514602e-04
## ASV1218     -3.292598e-38 -2.010199e-04 -2.103230e-04 -2.198323e-04
## ASV0436      2.946358e-39  1.331743e-05  1.384056e-05  1.422571e-05
## ASV0919      2.787107e-38  1.711740e-04  1.791669e-04  1.873197e-04
## ASV0577      1.197892e-38  7.322037e-05  7.667632e-05  8.014452e-05
## ASV2517      3.185481e-38  1.945977e-04  2.038982e-04  2.131155e-04
## ASV2628     -3.767529e-38 -2.362507e-04 -2.474003e-04 -2.588990e-04
## ASV1743     -3.405990e-38 -2.152824e-04 -2.255242e-04 -2.361009e-04
## ASV1678     -2.915553e-38 -1.856303e-04 -1.944034e-04 -2.035897e-04
## ASV0315      3.877318e-38  2.423240e-04  2.536752e-04  2.654343e-04
## ASV0253      1.830957e-38  1.129617e-04  1.183950e-04  1.238022e-04
## ASV1363      5.068679e-38  3.074871e-04  3.216947e-04  3.361258e-04
## ASV0995     -2.700195e-38 -1.686858e-04 -1.767244e-04 -1.849155e-04
## ASV4185     -1.260804e-38 -7.434328e-05 -7.777642e-05 -8.116074e-05
## ASV0782      2.405638e-38  1.534533e-04  1.607146e-04  1.683273e-04
## ASV3240     -2.904426e-38 -1.828621e-04 -1.914709e-04 -2.004176e-04
## ASV1392     -5.284547e-38 -3.318758e-04 -3.474738e-04 -3.636646e-04
## ASV8488     -1.200352e-38 -7.552078e-05 -7.899822e-05 -8.269069e-05
## ASV2814     -1.966965e-38 -1.231474e-04 -1.288803e-04 -1.348705e-04
## ASV0678     -3.908943e-38 -2.500311e-04 -2.619015e-04 -2.743377e-04
## ASV1295     -2.810054e-38 -1.754134e-04 -1.836099e-04 -1.921113e-04
## ASV7517     -1.780714e-38 -1.069464e-04 -1.119299e-04 -1.168989e-04
## ASV2996     -5.539339e-38 -3.421372e-04 -3.581900e-04 -3.745838e-04
## ASV2882     -5.239294e-38 -3.218551e-04 -3.367257e-04 -3.520480e-04
## ASV1317      3.154422e-38  1.976127e-04  2.069531e-04  2.165638e-04
## ASV9106     -5.235592e-38 -3.267484e-04 -3.420324e-04 -3.578601e-04
## ASV9688     -4.984323e-38 -3.108603e-04 -3.255079e-04 -3.405609e-04
## ASV6181     -4.990943e-38 -3.103362e-04 -3.249440e-04 -3.399245e-04
## ASV2936      1.175422e-39  9.038250e-06  9.512259e-06  1.003781e-05
## ASV0192     -2.128297e-38 -1.287285e-04 -1.344717e-04 -1.404788e-04
## ASV2509     -2.437611e-38 -1.562138e-04 -1.636759e-04 -1.714556e-04
## ASV0863      8.953436e-38  5.448168e-04  5.698605e-04  5.955230e-04
## ASV2762     -2.235036e-38 -1.396823e-04 -1.461929e-04 -1.529726e-04
## ASV4904     -4.781267e-38 -2.973558e-04 -3.113240e-04 -3.256787e-04
## ASV0571      1.671071e-38  1.015318e-04  1.065295e-04  1.113326e-04
## ASV13304    -6.609676e-39 -4.687697e-05 -4.918116e-05 -5.174039e-05
## ASV6863     -1.080011e-38 -6.750041e-05 -7.059813e-05 -7.387617e-05
## ASV4844      3.044650e-39  2.429113e-05  2.560657e-05  2.706548e-05
## ASV10779    -5.275301e-38 -3.265425e-04 -3.419023e-04 -3.575886e-04
## ASV7921     -4.416407e-38 -2.754550e-04 -2.883808e-04 -3.017197e-04
## ASV8458     -4.685252e-38 -2.878524e-04 -3.012329e-04 -3.149376e-04
## ASV2593     -7.190342e-39 -3.940412e-05 -4.114415e-05 -4.276659e-05
## ASV4410     -2.491929e-38 -1.561646e-04 -1.634415e-04 -1.710356e-04
## ASV0593      6.302221e-38  3.999655e-04  4.191121e-04  4.388331e-04
## ASV2669      3.842773e-38  2.344708e-04  2.452955e-04  2.563668e-04
## ASV0868     -4.923435e-38 -3.069522e-04 -3.213245e-04 -3.361777e-04
## ASV3123     -1.659969e-38 -1.074707e-04 -1.129689e-04 -1.183751e-04
## ASV3482     -2.027781e-38 -1.251315e-04 -1.309367e-04 -1.369208e-04
## ASV2552     -5.761207e-38 -3.463159e-04 -3.625599e-04 -3.786735e-04
## ASV0723      6.548178e-38  3.944410e-04  4.127884e-04  4.311765e-04
## ASV0526     -4.197203e-38 -2.611904e-04 -2.734074e-04 -2.860314e-04
## ASV4623     -1.871415e-38 -1.179297e-04 -1.234084e-04 -1.291751e-04
## ASV2070     -5.862263e-38 -3.641165e-04 -3.812087e-04 -3.987617e-04
## ASV1198      1.631923e-39  9.455039e-06  9.760426e-06  1.017174e-05
## ASV3034      2.758890e-39  1.560572e-05  1.603176e-05  1.669333e-05
## ASV1208     -7.021706e-39 -4.319985e-05 -4.525738e-05 -4.732411e-05
## ASV4860      9.235201e-39  5.882940e-05  6.170565e-05  6.461853e-05
## ASV2493     -1.811249e-38 -1.127878e-04 -1.180263e-04 -1.234776e-04
## ASV4217     -1.316017e-38 -7.808744e-05 -8.164926e-05 -8.521696e-05
## ASV1516     -6.710125e-39 -4.869653e-05 -5.115361e-05 -5.387270e-05
## ASV1186      2.158371e-38  1.347539e-04  1.409211e-04  1.474434e-04
## ASV1906     -1.864510e-38 -1.169099e-04 -1.225372e-04 -1.282402e-04
## ASV8220     -2.423491e-39 -1.816533e-05 -1.905412e-05 -2.009312e-05
## ASV4227     -4.296795e-38 -2.670673e-04 -2.795664e-04 -2.924491e-04
## ASV1013      2.595926e-38  1.671806e-04  1.751018e-04  1.834620e-04
## ASV7952     -2.810362e-38 -1.805732e-04 -1.892784e-04 -1.983045e-04
## ASV5923     -3.272647e-38 -2.059624e-04 -2.156447e-04 -2.257127e-04
## ASV0190     -4.176537e-38 -2.561965e-04 -2.681210e-04 -2.802966e-04
## ASV0491     -3.912354e-39 -2.771884e-05 -2.914572e-05 -3.066382e-05
## ASV9535     -1.764986e-38 -1.101035e-04 -1.152035e-04 -1.205276e-04
## ASV9947     -1.220474e-38 -8.190197e-05 -8.593190e-05 -9.020400e-05
## ASV6518     -1.156573e-38 -7.191753e-05 -7.531328e-05 -7.878825e-05
## ASV1741     -1.157422e-38 -7.371356e-05 -7.733438e-05 -8.099079e-05
## ASV1874      2.310758e-38  1.395646e-04  1.460938e-04  1.526138e-04
## ASV2150      6.286211e-39  3.949764e-05  4.140886e-05  4.333946e-05
## ASV5262     -1.199800e-38 -7.337375e-05 -7.676745e-05 -8.024382e-05
## ASV1729     -4.209242e-38 -2.638695e-04 -2.762569e-04 -2.891024e-04
## ASV1522     -7.010623e-39 -5.037918e-05 -5.305546e-05 -5.582639e-05
## ASV3250      9.367271e-39  5.663359e-05  5.919321e-05  6.183842e-05
## ASV4338     -4.281358e-38 -2.666399e-04 -2.791796e-04 -2.920727e-04
## ASV1386      5.091251e-38  3.183220e-04  3.332605e-04  3.487130e-04
## ASV0694     -5.280541e-39 -3.586574e-05 -3.751013e-05 -3.939614e-05
## ASV2026      3.751767e-39  2.822736e-05  2.966371e-05  3.128098e-05
## ASV0191     -3.483525e-38 -2.125785e-04 -2.224075e-04 -2.324476e-04
## ASV1641      1.607065e-38  1.029067e-04  1.079211e-04  1.130391e-04
## ASV1326      8.301652e-38  5.161503e-04  5.404710e-04  5.653833e-04
## ASV4786     -2.230045e-39 -1.536227e-05 -1.609469e-05 -1.691458e-05
## ASV0342      2.034193e-38  1.294865e-04  1.356055e-04  1.420108e-04
## ASV3025     -2.472267e-38 -1.504286e-04 -1.573835e-04 -1.644718e-04
## ASV6533     -4.202969e-38 -2.577286e-04 -2.696907e-04 -2.819370e-04
## ASV1898      4.594799e-38  2.880715e-04  3.016529e-04  3.156658e-04
## ASV1940      2.619137e-38  1.633855e-04  1.711288e-04  1.790393e-04
## ASV4968     -4.764662e-38 -2.983921e-04 -3.123486e-04 -3.268560e-04
## ASV3401     -2.516869e-38 -1.565666e-04 -1.638269e-04 -1.713816e-04
## ASV3211      1.451760e-38  9.371642e-05  9.819609e-05  1.028949e-04
## ASV1489     -6.682710e-38 -4.147101e-04 -4.341770e-04 -4.541449e-04
## ASV4139     -3.900016e-38 -2.430900e-04 -2.544670e-04 -2.662271e-04
## ASV6059     -4.113916e-38 -2.565738e-04 -2.685526e-04 -2.809724e-04
## ASV0918      1.093360e-38  6.510880e-05  6.808357e-05  7.107512e-05
## ASV1449      4.000056e-38  2.492890e-04  2.609644e-04  2.730240e-04
## ASV5652     -2.754336e-38 -1.712626e-04 -1.793864e-04 -1.876569e-04
## ASV4091     -1.943147e-39 -5.982020e-06 -6.134610e-06 -6.105732e-06
## ASV7638     -2.594639e-38 -1.593331e-04 -1.667115e-04 -1.742920e-04
## ASV6525     -3.706829e-38 -2.246156e-04 -2.349504e-04 -2.454935e-04
## ASV8959     -3.700607e-38 -2.315707e-04 -2.424571e-04 -2.537102e-04
## ASV0699      2.844740e-38  1.770863e-04  1.853707e-04  1.939122e-04
## ASV2925      3.452354e-38  2.169426e-04  2.271776e-04  2.377671e-04
## ASV0618      7.219910e-39  4.766619e-05  5.002519e-05  5.246478e-05
## ASV2083      5.018464e-39  3.326083e-05  3.494484e-05  3.666150e-05
## ASV6192     -4.556983e-38 -2.824383e-04 -2.956792e-04 -3.092613e-04
## ASV8640     -5.148762e-38 -3.193229e-04 -3.342709e-04 -3.496390e-04
## ASV1103      2.149890e-38  1.312781e-04  1.373343e-04  1.435463e-04
## ASV4240     -3.353191e-39 -1.598031e-05 -1.667639e-05 -1.720160e-05
## ASV2180      1.344607e-38  8.312271e-05  8.702725e-05  9.101621e-05
## ASV9157     -3.307252e-38 -2.047624e-04 -2.143102e-04 -2.241405e-04
## ASV1307      6.415343e-38  4.015145e-04  4.204117e-04  4.399265e-04
## ASV4960     -1.653270e-38 -1.004238e-04 -1.050491e-04 -1.097706e-04
## ASV3930     -1.406616e-38 -8.547606e-05 -8.941937e-05 -9.344439e-05
## ASV1200     -2.800829e-38 -1.756356e-04 -1.839455e-04 -1.924998e-04
## ASV4676     -1.441961e-38 -8.937840e-05 -9.356162e-05 -9.786067e-05
## ASV6993     -5.412234e-38 -3.323963e-04 -3.479324e-04 -3.637570e-04
## ASV4813     -2.092107e-38 -1.300788e-04 -1.360722e-04 -1.423402e-04
## ASV4364     -6.964206e-38 -4.286380e-04 -4.486678e-04 -4.691250e-04
## ASV0141      2.896778e-38  1.710394e-04  1.787975e-04  1.865853e-04
## ASV3509      1.642973e-38  1.071823e-04  1.124009e-04  1.178456e-04
## ASV2751      2.889865e-38  1.806039e-04  1.890864e-04  1.978511e-04
## ASV4913     -2.998635e-38 -1.852427e-04 -1.939084e-04 -2.027879e-04
## ASV0138      7.386171e-38  4.585610e-04  4.801881e-04  5.022958e-04
## ASV7697     -2.129214e-38 -1.292620e-04 -1.352235e-04 -1.412958e-04
## ASV1602      1.158982e-38  6.661215e-05  6.955973e-05  7.248385e-05
## ASV5976     -4.147301e-38 -2.570973e-04 -2.691043e-04 -2.814711e-04
## ASV7525     -4.279911e-38 -2.648960e-04 -2.772436e-04 -2.899620e-04
## ASV4961      1.936969e-38  1.196536e-04  1.253111e-04  1.310421e-04
## ASV2546      5.361939e-38  3.241216e-04  3.387858e-04  3.539327e-04
## ASV0721     -3.147587e-38 -1.951476e-04 -2.042741e-04 -2.136571e-04
## ASV0542      2.899991e-38  1.792970e-04  1.877279e-04  1.963337e-04
## ASV3865      1.882864e-38  1.149462e-04  1.202859e-04  1.257228e-04
## ASV5571     -3.451819e-38 -2.084702e-04 -2.181820e-04 -2.279241e-04
## ASV6804      3.511144e-39  2.552975e-05  2.682779e-05  2.825637e-05
## ASV4424      3.083974e-38  1.925458e-04  2.016097e-04  2.109376e-04
## ASV3395      2.417530e-38  1.424861e-04  1.488028e-04  1.552699e-04
## ASV2394     -3.040027e-38 -1.898807e-04 -1.987894e-04 -2.079978e-04
## ASV8629     -3.040027e-38 -1.898807e-04 -1.987743e-04 -2.079815e-04
## ASV1018      2.761158e-38  1.720351e-04  1.800355e-04  1.883524e-04
## ASV6139     -6.188109e-38 -3.849586e-04 -4.030683e-04 -4.216570e-04
## ASV10411    -3.161734e-38 -1.973956e-04 -2.066776e-04 -2.162479e-04
## ASV3992     -1.211140e-38 -7.672443e-05 -8.024430e-05 -8.401607e-05
## ASV7131     -2.355819e-39 -1.522148e-05 -1.582255e-05 -1.658133e-05
## ASV3729     -5.786726e-39 -3.274450e-05 -3.417555e-05 -3.558091e-05
## ASV2197     -6.990443e-39 -4.260302e-05 -4.452078e-05 -4.653001e-05
## ASV2426     -3.245921e-38 -1.987067e-04 -2.080004e-04 -2.174311e-04
## ASV3669     -2.919456e-38 -1.853044e-04 -1.940308e-04 -2.031719e-04
## ASV1820      1.591961e-38  9.797021e-05  1.025977e-04  1.072723e-04
## ASV7081     -2.810923e-38 -1.757156e-04 -1.839592e-04 -1.924906e-04
## ASV7872     -3.626603e-38 -2.237161e-04 -2.341177e-04 -2.448172e-04
## ASV1670     -4.820870e-39 -2.732090e-05 -2.849741e-05 -2.967204e-05
## ASV0712      3.344421e-38  2.153280e-04  2.256899e-04  2.364706e-04
## ASV0474      5.580430e-38  3.337950e-04  3.489150e-04  3.643422e-04
## ASV1196      5.269687e-38  3.289256e-04  3.442857e-04  3.602194e-04
## ASV0845      3.361745e-38  2.070936e-04  2.167379e-04  2.266392e-04
## ASV12393    -6.720861e-38 -4.192578e-04 -4.389982e-04 -4.593027e-04
## ASV5867     -2.570070e-38 -1.612027e-04 -1.688450e-04 -1.766980e-04
## ASV17619    -9.217831e-39 -6.059511e-05 -6.349302e-05 -6.659138e-05
## ASV4686     -2.262238e-38 -1.423333e-04 -1.490498e-04 -1.560102e-04
## ASV3520     -3.734315e-38 -2.321342e-04 -2.430046e-04 -2.542051e-04
## ASV10800    -6.063568e-38 -3.791161e-04 -3.969914e-04 -4.154011e-04
## ASV2706      5.356144e-38  3.362639e-04  3.520958e-04  3.684879e-04
## ASV1227     -7.836011e-39 -4.718554e-05 -4.938342e-05 -5.158206e-05
## ASV2621      4.856918e-38  3.082861e-04  3.229571e-04  3.381698e-04
## ASV0460      1.058262e-38  6.867972e-05  7.198703e-05  7.545256e-05
## ASV1069     -4.013579e-38 -2.524820e-04 -2.643826e-04 -2.767205e-04
## ASV6939     -3.781526e-38 -2.335146e-04 -2.444155e-04 -2.555993e-04
## ASV2862     -5.219391e-38 -3.242030e-04 -3.394497e-04 -3.550807e-04
## ASV1021     -3.120917e-38 -1.904943e-04 -1.994085e-04 -2.084198e-04
## ASV3845      2.398763e-38  1.504767e-04  1.575699e-04  1.648957e-04
## ASV0732      2.066603e-38  1.316825e-04  1.378914e-04  1.444111e-04
## ASV10731     1.656501e-38  1.018929e-04  1.066852e-04  1.115452e-04
## ASV3378      2.039950e-38  1.221437e-04  1.276924e-04  1.333376e-04
## ASV7154      2.327404e-39  1.023274e-05  1.065491e-05  1.092536e-05
## ASV9876      8.781653e-39  5.634575e-05  5.905129e-05  6.186114e-05
## ASV0631      4.002639e-38  2.533981e-04  2.653662e-04  2.778343e-04
## ASV13027    -3.040027e-38 -1.917868e-04 -2.007892e-04 -2.101882e-04
## ASV2497     -3.040027e-38 -1.917868e-04 -2.007739e-04 -2.101715e-04
## ASV3966     -4.276501e-38 -2.703421e-04 -2.830596e-04 -2.963365e-04
## ASV2574      2.681653e-38  1.619625e-04  1.695227e-04  1.770925e-04
## ASV0545     -2.358888e-38 -1.499638e-04 -1.570812e-04 -1.644811e-04
## ASV8453     -2.701459e-38 -1.702492e-04 -1.782500e-04 -1.865864e-04
## ASV0221     -1.436321e-38 -9.007618e-05 -9.431342e-05 -9.869976e-05
## ASV3305      1.903450e-38  1.213072e-04  1.271975e-04  1.332174e-04
## ASV2647     -1.382212e-38 -8.420160e-05 -8.807563e-05 -9.204488e-05
## ASV5789     -6.140388e-38 -3.880660e-04 -4.063723e-04 -4.254316e-04
## ASV1731     -2.088928e-38 -1.236289e-04 -1.293682e-04 -1.350188e-04
## ASV3857      8.970316e-39  5.463725e-05  5.716708e-05  5.974511e-05
## ASV0405      3.776918e-38  2.296122e-04  2.402861e-04  2.510931e-04
## ASV0094     -4.463495e-38 -2.639514e-04 -2.757301e-04 -2.877802e-04
## ASV0158     -2.203770e-39 -9.960242e-06 -1.029840e-05 -1.059245e-05
## ASV5507     -3.683166e-38 -2.293418e-04 -2.400269e-04 -2.511083e-04
## ASV1023     -1.262033e-39 -2.657244e-06 -2.657473e-06 -2.508781e-06
## ASV0488     -2.385343e-38 -1.490640e-04 -1.560438e-04 -1.632731e-04
## ASV1459      2.088266e-38  1.258465e-04  1.315737e-04  1.374414e-04
## ASV4349     -6.567031e-39 -3.795884e-05 -3.972643e-05 -4.141334e-05
## ASV1172      6.265962e-38  3.870047e-04  4.050819e-04  4.236188e-04
## ASV10187    -1.584248e-38 -1.012312e-04 -1.059901e-04 -1.110174e-04
## ASV7227      9.469253e-39  5.983662e-05  6.277531e-05  6.572220e-05
## ASV10340     9.107694e-39  5.857218e-05  6.144260e-05  6.437918e-05
## ASV10821    -1.761531e-38 -1.096192e-04 -1.146606e-04 -1.199467e-04
## ASV13810    -1.761531e-38 -1.096192e-04 -1.146521e-04 -1.199373e-04
## ASV3230     -1.410410e-38 -8.802138e-05 -9.204916e-05 -9.630440e-05
## ASV5524      1.733267e-39  9.224622e-06  9.757601e-06  1.013115e-05
## ASV8742     -1.761531e-38 -1.096192e-04 -1.146375e-04 -1.199210e-04
## ASV9188      3.992908e-38  2.424561e-04  2.537867e-04  2.651873e-04
## ASV4658      1.966638e-38  1.224225e-04  1.282782e-04  1.341991e-04
## ASV7889      2.499059e-38  1.499814e-04  1.568040e-04  1.637648e-04
## ASV1466      4.679535e-39  3.395611e-05  3.581877e-05  3.772160e-05
## ASV1424     -1.295084e-38 -7.166497e-05 -7.482777e-05 -7.782212e-05
## ASV0098     -2.976340e-38 -1.881115e-04 -1.970667e-04 -2.063001e-04
## ASV0067     -4.840102e-38 -3.014637e-04 -3.155641e-04 -3.301321e-04
## ASV9434     -2.022495e-38 -1.251776e-04 -1.311026e-04 -1.371173e-04
## ASV3270     -7.643380e-39 -4.919917e-05 -5.160656e-05 -5.406884e-05
## ASV4518     -3.490079e-38 -2.147222e-04 -2.247436e-04 -2.349854e-04
## ASV7661     -3.338061e-38 -2.023259e-04 -2.117491e-04 -2.212434e-04
## ASV4223      3.588748e-39  2.293499e-05  2.406129e-05  2.519858e-05
## ASV3481      2.611052e-38  1.709968e-04  1.792399e-04  1.879513e-04
## ASV7819     -5.088070e-38 -3.165658e-04 -3.314256e-04 -3.467171e-04
## ASV3095     -2.357105e-39 -1.371502e-05 -1.427221e-05 -1.487753e-05
## ASV4476     -1.013193e-38 -6.484205e-05 -6.787450e-05 -7.109885e-05
## ASV1713      3.181440e-38  1.916884e-04  2.005754e-04  2.095131e-04
## ASV11165    -8.468706e-39 -5.027694e-05 -5.252023e-05 -5.481483e-05
## ASV2179      6.285935e-38  3.920582e-04  4.105072e-04  4.294918e-04
## ASV3747      5.393274e-38  3.361877e-04  3.519593e-04  3.682225e-04
## ASV1410      3.553342e-39  1.856253e-05  1.932571e-05  2.003600e-05
## ASV6069     -3.385004e-38 -2.112077e-04 -2.210691e-04 -2.312968e-04
## ASV1939      8.979039e-39  5.826510e-05  6.108210e-05  6.402371e-05
## ASV7865     -5.284404e-38 -3.291990e-04 -3.446387e-04 -3.605537e-04
## ASV4488     -4.805763e-38 -3.021753e-04 -3.164111e-04 -3.311706e-04
## ASV0938      3.858265e-38  2.393716e-04  2.505557e-04  2.620782e-04
## ASV7852     -2.967785e-38 -1.819876e-04 -1.904824e-04 -1.991366e-04
## ASV2503     -2.209837e-39 -1.659019e-05 -1.740378e-05 -1.836021e-05
## ASV2993     -4.122813e-38 -2.588427e-04 -2.710070e-04 -2.836270e-04
## ASV3752     -5.274548e-39 -3.211412e-05 -3.356478e-05 -3.507738e-05
## ASV2557     -4.191849e-38 -2.635474e-04 -2.760664e-04 -2.889319e-04
## ASV6522     -9.007829e-39 -5.477398e-05 -5.730506e-05 -5.988232e-05
## ASV0088     -3.308933e-38 -1.972935e-04 -2.064256e-04 -2.155125e-04
## ASV7935     -2.642181e-38 -1.635758e-04 -1.712604e-04 -1.791202e-04
## ASV0942     -3.308049e-38 -2.079737e-04 -2.176955e-04 -2.278437e-04
## ASV7709     -4.010930e-38 -2.444468e-04 -2.558572e-04 -2.673999e-04
## ASV4588     -2.096652e-38 -1.253618e-04 -1.313071e-04 -1.371097e-04
## ASV5765     -5.601122e-38 -3.476535e-04 -3.639446e-04 -3.806882e-04
## ASV3562     -3.471049e-39 -1.834182e-05 -1.906265e-05 -1.977156e-05
## ASV9076     -4.259211e-38 -2.656545e-04 -2.780984e-04 -2.909613e-04
## ASV4707     -4.738833e-38 -2.962376e-04 -3.101912e-04 -3.245725e-04
## ASV2188      3.330284e-38  2.105652e-04  2.205422e-04  2.308899e-04
## ASV0613      5.627959e-39  3.884251e-05  4.064057e-05  4.270089e-05
## ASV0663     -2.128331e-38 -1.334838e-04 -1.397481e-04 -1.462489e-04
## ASV3361     -4.484393e-38 -2.666744e-04 -2.790375e-04 -2.912924e-04
## ASV1478      4.786493e-38  2.947571e-04  3.085124e-04  3.225855e-04
## ASV0213      2.649891e-38  1.636410e-04  1.713268e-04  1.791670e-04
## ASV7674     -1.468918e-38 -8.974063e-05 -9.387951e-05 -9.812733e-05
## ASV2137     -1.584706e-38 -9.625833e-05 -1.007163e-04 -1.052428e-04
## ASV8246     -1.303075e-38 -8.003929e-05 -8.377837e-05 -8.759305e-05
## ASV0047     -4.150135e-38 -2.538915e-04 -2.657137e-04 -2.777503e-04
## ASV6117      1.039659e-39  8.341143e-06  8.819576e-06  9.319976e-06
## ASV3349     -7.756286e-39 -4.842211e-05 -5.066403e-05 -5.300838e-05
## ASV10881    -2.662156e-38 -1.659203e-04 -1.736899e-04 -1.817129e-04
## ASV6979     -1.776051e-38 -1.119416e-04 -1.172010e-04 -1.226806e-04
## ASV7930     -3.502775e-38 -2.171707e-04 -2.272508e-04 -2.376924e-04
## ASV7322      1.160320e-38  7.268315e-05  7.618500e-05  7.972419e-05
## ASV4927     -5.597831e-39 -3.659796e-05 -3.829264e-05 -4.014876e-05
## ASV9054     -1.974473e-38 -1.213696e-04 -1.270452e-04 -1.328343e-04
## ASV2692     -1.415235e-38 -9.325971e-05 -9.787176e-05 -1.026270e-04
## ASV1666     -1.128303e-38 -6.512005e-05 -6.800987e-05 -7.088612e-05
## ASV4728      2.296259e-38  1.398116e-04  1.461468e-04  1.527348e-04
## ASV3097      1.455704e-38  9.256484e-05  9.695195e-05  1.015279e-04
## ASV4962     -1.109023e-38 -7.394556e-05 -7.757354e-05 -8.140323e-05
## ASV5057      1.774724e-38  1.134256e-04  1.188213e-04  1.244590e-04
## ASV2639      3.221944e-38  2.052521e-04  2.150166e-04  2.251795e-04
## ASV1808     -2.684481e-39 -2.363903e-05 -2.503301e-05 -2.653633e-05
## ASV6333     -5.520018e-39 -3.834703e-05 -4.022320e-05 -4.228480e-05
## ASV4328     -1.484326e-38 -9.219545e-05 -9.651742e-05 -1.009611e-04
## ASV7707     -4.416514e-38 -2.716547e-04 -2.844220e-04 -2.973783e-04
## ASV11022    -4.299931e-38 -2.637218e-04 -2.760366e-04 -2.885750e-04
## ASV1469     -8.052818e-39 -4.942537e-05 -5.161795e-05 -5.396413e-05
## ASV3919     -1.414495e-38 -9.051565e-05 -9.480915e-05 -9.930821e-05
## ASV4038     -2.976963e-38 -1.842646e-04 -1.929572e-04 -2.018117e-04
## ASV4048      9.918914e-39  6.539359e-05  6.858578e-05  7.193452e-05
## ASV0634      1.196956e-38  7.595324e-05  7.953748e-05  8.328684e-05
## ASV1852     -3.229859e-38 -2.067775e-04 -2.166479e-04 -2.269402e-04
## ASV2505      2.518163e-38  1.561750e-04  1.634463e-04  1.709628e-04
## ASV1762     -3.875928e-38 -2.398112e-04 -2.509575e-04 -2.624645e-04
## ASV3761     -3.280191e-38 -2.034671e-04 -2.129224e-04 -2.227104e-04
## ASV0775     -5.573295e-38 -3.450361e-04 -3.611855e-04 -3.777554e-04
## ASV10911    -4.097607e-38 -2.531088e-04 -2.649103e-04 -2.770376e-04
## ASV1339     -7.150682e-39 -4.325532e-05 -4.515354e-05 -4.716675e-05
## ASV5214     -9.525510e-39 -5.784683e-05 -6.046549e-05 -6.317816e-05
## ASV4945      1.063081e-38  6.677125e-05  6.995175e-05  7.320830e-05
## ASV5624     -9.451872e-39 -5.504897e-05 -5.749199e-05 -5.994980e-05
## ASV3429     -5.411225e-39 -3.129353e-05 -3.280992e-05 -3.420863e-05
## ASV8416     -3.964180e-39 -2.866923e-05 -3.015641e-05 -3.175097e-05
## ASV2400     -5.014752e-38 -3.120316e-04 -3.265810e-04 -3.416430e-04
## ASV3388     -1.585134e-38 -1.014405e-04 -1.062274e-04 -1.112690e-04
## ASV7089      1.078438e-38  6.386509e-05  6.675945e-05  6.966978e-05
## ASV3396     -1.706649e-38 -1.041804e-04 -1.090397e-04 -1.139607e-04
## ASV0343      2.253455e-38  1.477895e-04  1.549308e-04  1.624655e-04
## ASV5505     -3.002117e-38 -1.888784e-04 -1.977438e-04 -2.069745e-04
## ASV6721     -1.388994e-38 -8.897990e-05 -9.315621e-05 -9.758549e-05
## ASV0537      1.083073e-38  7.668687e-05  8.060197e-05  8.479140e-05
## ASV7753     -3.924621e-38 -2.452021e-04 -2.566482e-04 -2.685380e-04
## ASV5022     -2.426241e-39 -1.928400e-05 -2.032874e-05 -2.147642e-05
## ASV1073      5.477660e-38  3.424264e-04  3.585078e-04  3.751265e-04
## ASV1347     -1.843176e-53 -7.378587e-07 -7.505202e-07 -8.295470e-07
## ASV15032     1.716686e-38  1.038526e-04  1.086769e-04  1.135331e-04
## ASV18213    -1.843176e-53 -7.378641e-07 -7.572392e-07 -8.365261e-07
## ASV20691     1.380943e-38  8.745635e-05  9.163427e-05  9.593565e-05
## ASV4260     -7.189165e-39 -4.502563e-05 -4.712375e-05 -4.931895e-05
## ASV4923      1.201268e-38  7.597138e-05  7.959908e-05  8.332917e-05
## ASV7995     -1.843176e-53 -7.378612e-07 -7.656641e-07 -8.454530e-07
## ASV8960      2.476201e-38  1.535265e-04  1.607482e-04  1.681293e-04
## ASV10682     1.973690e-38  1.171999e-04  1.225136e-04  1.278740e-04
## ASV11911    -1.843176e-53 -7.378788e-07 -7.817363e-07 -8.625030e-07
## ASV14296     3.029779e-38  1.849851e-04  1.935955e-04  2.023389e-04
## ASV2314      1.571118e-38  1.049800e-04  1.101566e-04  1.156044e-04
## ASV3819      1.953065e-38  1.194147e-04  1.249598e-04  1.306079e-04
## ASV4517     -8.601489e-53 -7.378795e-07 -8.057896e-07 -8.883055e-07
## ASV8941      3.624761e-38  2.277662e-04  2.384662e-04  2.495778e-04
## ASV1444      8.601489e-53  7.378818e-07  8.170046e-07  9.005041e-07
## ASV5959      6.784199e-39  4.167676e-05  4.359344e-05  4.556887e-05
## ASV3623     -1.724633e-38 -1.055589e-04 -1.103678e-04 -1.153716e-04
## ASV0260      2.024028e-38  1.269794e-04  1.329433e-04  1.391305e-04
## ASV4401     -1.204246e-38 -8.304616e-05 -8.737652e-05 -9.178812e-05
## ASV2891     -4.408109e-38 -2.770481e-04 -2.900933e-04 -3.036208e-04
## ASV2778     -9.969306e-39 -6.236515e-05 -6.529702e-05 -6.832813e-05
## ASV8744      2.051786e-38  1.227527e-04  1.282949e-04  1.339719e-04
## ASV1079      4.153702e-38  2.518380e-04  2.632976e-04  2.751136e-04
## ASV19688     2.500328e-39  1.859260e-05  1.959729e-05  2.065919e-05
## ASV4039      4.355508e-39  3.075374e-05  3.236437e-05  3.404862e-05
## ASV4982     -3.040027e-38 -1.885135e-04 -1.972423e-04 -2.063063e-04
## ASV1071     -3.040027e-38 -1.885135e-04 -1.972276e-04 -2.062902e-04
## ASV7666     -3.040027e-38 -1.885135e-04 -1.972128e-04 -2.062741e-04
## ASV0502      4.220335e-38  2.635080e-04  2.758206e-04  2.885891e-04
## ASV3624     -3.040027e-38 -1.887821e-04 -1.974954e-04 -2.065817e-04
## ASV0403      4.682997e-39  2.715393e-05  2.824295e-05  2.944286e-05
## ASV4939     -3.040027e-38 -1.887821e-04 -1.974791e-04 -2.065638e-04
## ASV6297     -3.605016e-38 -2.258223e-04 -2.364340e-04 -2.474168e-04
## ASV6343      3.400843e-38  2.022040e-04  2.113099e-04  2.205898e-04
## ASV0954     -7.556871e-39 -4.281063e-05 -4.472364e-05 -4.656755e-05
## ASV10225    -1.281403e-38 -8.198314e-05 -8.596990e-05 -9.004248e-05
## ASV1584      5.284594e-38  3.280657e-04  3.433894e-04  3.591889e-04
## ASV1803      2.011038e-38  1.208411e-04  1.263472e-04  1.319497e-04
## ASV2576     -5.284594e-38 -3.280657e-04 -3.433562e-04 -3.591531e-04
## ASV3252      3.409593e-38  2.131847e-04  2.232321e-04  2.335818e-04
## ASV3463     -5.284594e-38 -3.280657e-04 -3.433290e-04 -3.591236e-04
## ASV3822     -3.957697e-38 -2.491155e-04 -2.608625e-04 -2.730481e-04
## ASV4926     -2.238915e-38 -1.330036e-04 -1.391014e-04 -1.451965e-04
## ASV5564     -1.365277e-38 -8.479790e-05 -8.874238e-05 -9.282992e-05
## ASV5595     -8.015824e-39 -4.952602e-05 -5.181020e-05 -5.418404e-05
## ASV16463    -3.040027e-38 -1.909549e-04 -1.999117e-04 -2.092282e-04
## ASV6277      2.997969e-38  1.905645e-04  1.996316e-04  2.090419e-04
## ASV1344      3.040027e-38  1.909549e-04  1.999046e-04  2.092204e-04
## ASV1869      2.027390e-38  1.221720e-04  1.278721e-04  1.335651e-04
## ASV8155     -1.751049e-38 -1.048286e-04 -1.096710e-04 -1.145192e-04
## ASV2502     -3.121633e-38 -1.930013e-04 -2.020771e-04 -2.113357e-04
## ASV6742     -1.036673e-38 -6.063499e-05 -6.325798e-05 -6.597718e-05
## ASV3124     -2.035493e-38 -1.253401e-04 -1.312519e-04 -1.372491e-04
## ASV17042    -3.538879e-38 -2.195174e-04 -2.297631e-04 -2.403238e-04
## ASV0248      4.951509e-38  3.044588e-04  3.187058e-04  3.332258e-04
## ASV4557      7.240290e-39  5.129801e-05  5.380679e-05  5.659842e-05
## ASV3507     -5.318894e-38 -3.334160e-04 -3.490772e-04 -3.653067e-04
## ASV1870      3.925686e-39  2.451452e-05  2.565442e-05  2.684114e-05
## ASV2447     -2.538170e-38 -1.605589e-04 -1.681094e-04 -1.760053e-04
## ASV0347      4.138318e-38  2.607439e-04  2.730120e-04  2.857775e-04
## ASV1855     -1.910553e-38 -1.197535e-04 -1.253054e-04 -1.311309e-04
## ASV0568      1.460272e-38  9.006745e-05  9.426803e-05  9.857667e-05
## ASV1620     -2.568366e-38 -1.604123e-04 -1.678007e-04 -1.755654e-04
## ASV0101     -2.210653e-38 -1.302780e-04 -1.360795e-04 -1.419912e-04
## ASV7751      1.844488e-38  1.202780e-04  1.260394e-04  1.321393e-04
## ASV9033     -3.491267e-38 -2.191900e-04 -2.294851e-04 -2.401727e-04
## ASV3438     -9.992641e-39 -6.354684e-05 -6.650713e-05 -6.964670e-05
## ASV0637     -3.283357e-38 -2.047400e-04 -2.143703e-04 -2.242803e-04
## ASV1181     -2.405905e-38 -1.512350e-04 -1.583709e-04 -1.657528e-04
## ASV13480    -3.040027e-38 -1.905209e-04 -1.994803e-04 -2.087521e-04
## ASV14220    -3.040027e-38 -1.905209e-04 -1.994651e-04 -2.087356e-04
## ASV1448     -2.207886e-38 -1.391295e-04 -1.456730e-04 -1.524831e-04
## ASV1457      2.119314e-38  1.284985e-04  1.344113e-04  1.404352e-04
## ASV1645      1.447726e-38  9.222062e-05  9.660243e-05  1.011672e-04
## ASV2300     -2.015774e-38 -1.242406e-04 -1.300007e-04 -1.359325e-04
## ASV2533      3.110348e-38  1.911761e-04  2.001034e-04  2.092099e-04
## ASV5059      8.200787e-39  4.739254e-05  4.941722e-05  5.150959e-05
## ASV8871     -3.040027e-38 -1.905209e-04 -1.994593e-04 -2.087290e-04
## ASV1289     -3.309782e-38 -2.042898e-04 -2.137817e-04 -2.235579e-04
## ASV3983     -1.365234e-38 -8.689047e-05 -9.096320e-05 -9.525713e-05
## ASV10323    -1.041118e-38 -6.874318e-05 -7.202488e-05 -7.554881e-05
## ASV13279    -3.040027e-38 -1.905209e-04 -1.994209e-04 -2.086870e-04
## ASV7149     -3.040027e-38 -1.905209e-04 -1.994058e-04 -2.086706e-04
## ASV1691      5.674663e-39  3.634495e-05  3.797525e-05  3.978105e-05
## ASV1649      1.476393e-38  9.356678e-05  9.797366e-05  1.025752e-04
## ASV10120     4.218114e-39  2.746433e-05  2.876642e-05  3.015625e-05
## ASV8285     -3.811186e-38 -2.425896e-04 -2.541507e-04 -2.661480e-04
## ASV0037     -3.302277e-38 -2.086718e-04 -2.186016e-04 -2.288527e-04
## ASV1770      8.758316e-39  5.461805e-05  5.715598e-05  5.980205e-05
## ASV2252      8.374943e-39  5.226610e-05  5.468663e-05  5.721327e-05
## ASV7580      3.475586e-38  2.115718e-04  2.213089e-04  2.312775e-04
## ASV5643     -3.085640e-38 -1.928210e-04 -2.018508e-04 -2.112061e-04
## ASV2722     -9.384900e-39 -6.168167e-05 -6.465802e-05 -6.781417e-05
## ASV2662     -2.105348e-38 -1.322625e-04 -1.384446e-04 -1.449001e-04
## ASV0479     -4.905052e-38 -3.022591e-04 -3.162551e-04 -3.306940e-04
## ASV2009     -5.226628e-38 -3.183983e-04 -3.331569e-04 -3.481742e-04
## ASV3731     -3.492426e-38 -2.144214e-04 -2.244078e-04 -2.346096e-04
## ASV5497     -4.276841e-38 -2.650976e-04 -2.774693e-04 -2.902182e-04
## ASV6647      2.236488e-39  1.182197e-05  1.238654e-05  1.284745e-05
## ASV8974     -3.166542e-38 -1.954898e-04 -2.045657e-04 -2.139204e-04
## ASV15527     2.932468e-39  1.714342e-05  1.796233e-05  1.873531e-05
## ASV6705     -1.804951e-38 -1.197541e-04 -1.255638e-04 -1.317413e-04
## ASV0354      3.996752e-38  2.497325e-04  2.614194e-04  2.735321e-04
## ASV2707      9.718478e-39  5.743385e-05  5.995803e-05  6.256400e-05
## ASV11167    -5.281250e-38 -3.282342e-04 -3.436250e-04 -3.594538e-04
## ASV6393     -4.189279e-38 -2.611269e-04 -2.733810e-04 -2.860152e-04
## ASV3808     -3.059405e-38 -1.863782e-04 -1.952193e-04 -2.040274e-04
## ASV9337      4.645467e-39  2.605494e-05  2.719232e-05  2.829562e-05
## ASV5043     -4.300017e-38 -2.679127e-04 -2.804645e-04 -2.934193e-04
## ASV4189     -1.703631e-39 -8.022177e-06 -8.292015e-06 -8.540443e-06
## ASV1304     -1.760863e-38 -1.027025e-04 -1.071859e-04 -1.117856e-04
## ASV2105     -2.248068e-38 -1.404589e-04 -1.469656e-04 -1.537739e-04
## ASV2421     -7.654459e-39 -4.881651e-05 -5.106578e-05 -5.348460e-05
## ASV3170      3.558411e-38  2.241943e-04  2.347933e-04  2.457706e-04
## ASV5036      4.836028e-38  3.007073e-04  3.148170e-04  3.293301e-04
## ASV2286      3.040027e-38  1.897510e-04  1.985626e-04  2.077516e-04
## ASV3363      2.977992e-38  1.893119e-04  1.983785e-04  2.077394e-04
## ASV5759     -2.580681e-39 -1.740408e-05 -1.820321e-05 -1.911424e-05
## ASV5440     -2.030115e-38 -1.310067e-04 -1.372696e-04 -1.438424e-04
## ASV2050      3.623413e-38  2.186938e-04  2.287286e-04  2.389201e-04
## ASV4478      2.428010e-38  1.550368e-04  1.624293e-04  1.701267e-04
## ASV5725     -2.724618e-38 -1.677015e-04 -1.754074e-04 -1.834048e-04
## ASV1600     -6.457862e-39 -4.767228e-05 -5.015940e-05 -5.285313e-05
## ASV1654     -4.841405e-38 -2.984656e-04 -3.122540e-04 -3.265165e-04
## ASV3781     -2.119260e-38 -1.289778e-04 -1.348333e-04 -1.409007e-04
## ASV7144     -1.828655e-38 -1.106699e-04 -1.158356e-04 -1.210184e-04
## ASV12710    -7.391208e-39 -4.115443e-05 -4.288777e-05 -4.461537e-05
## ASV3317      2.424066e-38  1.503901e-04  1.573732e-04  1.646155e-04
## ASV3249     -4.736936e-38 -2.945087e-04 -3.082004e-04 -3.223989e-04
## ASV0669     -3.034387e-38 -1.840377e-04 -1.924693e-04 -2.011038e-04
## ASV0893      1.761531e-38  1.086409e-04  1.137095e-04  1.189058e-04
## ASV11060    -1.761531e-38 -1.086409e-04 -1.137009e-04 -1.188966e-04
## ASV3207      5.895205e-38  3.738704e-04  3.915441e-04  4.099673e-04
## ASV3498     -1.761531e-38 -1.086409e-04 -1.136997e-04 -1.188954e-04
## ASV4358      1.109389e-38  6.881146e-05  7.204995e-05  7.536149e-05
## ASV4806      2.999849e-38  1.863527e-04  1.951439e-04  2.041281e-04
## ASV4941      1.761531e-38  1.086409e-04  1.136950e-04  1.188903e-04
## ASV6998      5.234933e-39  3.253659e-05  3.405861e-05  3.562454e-05
## ASV7327     -1.761531e-38 -1.086409e-04 -1.136885e-04 -1.188833e-04
## ASV5112      3.482204e-38  2.192409e-04  2.295998e-04  2.403179e-04
## ASV5345     -1.761531e-38 -1.086409e-04 -1.136728e-04 -1.188664e-04
## ASV8911     -1.761531e-38 -1.086409e-04 -1.136643e-04 -1.188572e-04
## ASV5061      4.085493e-38  2.536328e-04  2.655230e-04  2.777387e-04
## ASV1968     -3.222116e-39 -2.212820e-05 -2.325291e-05 -2.443364e-05
## ASV4669     -1.761531e-38 -1.086409e-04 -1.136485e-04 -1.188401e-04
## ASV6209     -6.915139e-39 -4.043491e-05 -4.220175e-05 -4.401238e-05
## ASV6938      3.517061e-38  2.159300e-04  2.259522e-04  2.362210e-04
## ASV6987      2.003492e-38  1.201685e-04  1.256870e-04  1.312542e-04
## ASV7842     -1.761531e-38 -1.086409e-04 -1.136444e-04 -1.188355e-04
## ASV17950     1.404325e-53  4.153973e-08  7.060140e-08  7.535778e-08
## ASV3380     -5.168331e-38 -3.164074e-04 -3.311699e-04 -3.461813e-04
## ASV13740    -4.294788e-38 -2.693768e-04 -2.820232e-04 -2.951443e-04
## ASV4313     -2.528080e-38 -1.581179e-04 -1.654718e-04 -1.731434e-04
## ASV3891     -2.793767e-38 -1.646700e-04 -1.723195e-04 -1.798107e-04
## ASV3322     -3.070413e-38 -1.913492e-04 -2.002732e-04 -2.095279e-04
## ASV1668     -5.073826e-39 -3.295342e-05 -3.445860e-05 -3.612549e-05
## ASV1739      1.243720e-38  7.424952e-05  7.757296e-05  8.098769e-05
## ASV3194      2.457088e-38  1.525291e-04  1.596033e-04  1.669464e-04
## ASV0071     -3.885679e-38 -2.304160e-04 -2.406914e-04 -2.512234e-04
## ASV0695      1.737182e-38  1.105566e-04  1.157141e-04  1.211627e-04
## ASV3835     -1.421637e-38 -8.662171e-05 -9.066189e-05 -9.474988e-05
## ASV1876      1.410429e-38  8.928754e-05  9.353481e-05  9.792487e-05
## ASV4892     -4.246804e-38 -2.653634e-04 -2.778638e-04 -2.907405e-04
## ASV1212     -1.477617e-38 -9.152865e-05 -9.575942e-05 -1.001579e-04
## ASV2640      3.628634e-40  1.380846e-06  1.346229e-06  1.361058e-06
## ASV7236     -4.178066e-38 -2.623329e-04 -2.746554e-04 -2.874474e-04
## ASV2353     -1.136627e-38 -7.330739e-05 -7.677952e-05 -8.045591e-05
## ASV0276      5.297941e-38  3.195025e-04  3.345086e-04  3.494365e-04
## ASV2262     -1.567746e-38 -9.738002e-05 -1.018208e-04 -1.065136e-04
## ASV11201    -1.012069e-38 -6.505832e-05 -6.812014e-05 -7.136842e-05
## ASV0665      4.368155e-39  2.630232e-05  2.750677e-05  2.873579e-05
## ASV5238      5.689398e-39  2.707901e-05  2.796191e-05  2.882414e-05
## ASV6885     -2.331070e-38 -1.441928e-04 -1.508976e-04 -1.578152e-04
## ASV1844      8.573873e-39  5.835171e-05  6.118078e-05  6.426061e-05
## ASV0379      3.040027e-38  1.881053e-04  1.968199e-04  2.058426e-04
## ASV1040     -9.902104e-39 -5.901721e-05 -6.163289e-05 -6.434318e-05
## ASV7913     -1.752280e-38 -1.091092e-04 -1.141778e-04 -1.194457e-04
## ASV1197     -3.040027e-38 -1.881053e-04 -1.967934e-04 -2.058138e-04
## ASV5918      1.299749e-38  8.135371e-05  8.522954e-05  8.918852e-05
## ASV8045      6.221209e-39  4.193262e-05  4.406153e-05  4.625739e-05
## ASV16458    -3.472051e-39 -1.902343e-05 -1.977009e-05 -2.054654e-05
## ASV10827    -3.040027e-38 -1.881053e-04 -1.967829e-04 -2.058023e-04
## ASV3658     -3.040027e-38 -1.881053e-04 -1.967682e-04 -2.057863e-04
## ASV0073     -6.214215e-38 -3.897822e-04 -4.080578e-04 -4.270334e-04
## ASV1951     -1.155586e-38 -7.843090e-05 -8.238386e-05 -8.651478e-05
## ASV7630     -3.993133e-38 -2.479903e-04 -2.596152e-04 -2.715665e-04
## ASV9449     -2.069183e-38 -1.320937e-04 -1.384554e-04 -1.450124e-04
## ASV3944      4.302148e-38  2.663418e-04  2.787381e-04  2.915314e-04
## ASV1520     -5.841721e-38 -3.603328e-04 -3.770869e-04 -3.943150e-04
## ASV0307      4.418851e-38  2.782776e-04  2.914286e-04  3.050469e-04
## ASV12731    -1.095031e-38 -7.059797e-05 -7.391422e-05 -7.745308e-05
## ASV0282      4.436702e-38  2.794136e-04  2.925968e-04  3.062694e-04
## ASV2646      4.152743e-38  2.509374e-04  2.625104e-04  2.742390e-04
## ASV3536      3.198782e-38  1.993123e-04  2.086419e-04  2.182783e-04
## ASV10089    -3.040027e-38 -1.836718e-04 -1.921487e-04 -2.007331e-04
## ASV1185      3.040027e-38  1.836717e-04  1.921343e-04  2.007179e-04
## ASV1452      3.040027e-38  1.836717e-04  1.921201e-04  2.007027e-04
## ASV1700      3.040027e-38  1.836717e-04  1.921058e-04  2.006875e-04
## ASV6948     -3.040027e-38 -1.836717e-04 -1.920916e-04 -2.006723e-04
## ASV0389     -3.943704e-38 -2.396933e-04 -2.507067e-04 -2.619775e-04
## ASV11884    -5.253884e-40  1.887392e-06  2.177311e-06  2.536095e-06
## ASV23165    -3.040027e-38 -1.836716e-04 -1.920605e-04 -2.006392e-04
## ASV2841      3.040027e-38  1.836716e-04  1.920464e-04  2.006240e-04
## ASV2949      3.040027e-38  1.836716e-04  1.920323e-04  2.006088e-04
## ASV4037      3.040027e-38  1.836716e-04  1.920181e-04  2.005936e-04
## ASV4477      3.040027e-38  1.836715e-04  1.920041e-04  2.005784e-04
## ASV4496      3.040027e-38  1.836715e-04  1.919900e-04  2.005633e-04
## ASV5784     -3.040027e-38 -1.836715e-04 -1.919760e-04 -2.005481e-04
## ASV6035      1.907164e-40  4.395966e-06  4.807635e-06  5.194309e-06
## ASV6232     -3.045296e-38 -1.839988e-04 -1.923052e-04 -2.008920e-04
## ASV1818      3.040027e-38  1.836715e-04  1.919485e-04  2.005183e-04
## ASV2595      3.040027e-38  1.836714e-04  1.919345e-04  2.005031e-04
## ASV2788     -3.942844e-39 -2.394801e-05 -2.519668e-05 -2.633223e-05
## ASV5018      3.040027e-38  1.836714e-04  1.919219e-04  2.004892e-04
## ASV0127      3.946275e-38  2.482308e-04  2.599069e-04  2.720360e-04
## ASV1527      6.855792e-40  5.752538e-06  6.058213e-06  6.411032e-06
## ASV1055      2.270216e-38  1.409741e-04  1.475074e-04  1.542930e-04
## ASV4791      1.644295e-38  9.131001e-05  9.517163e-05  9.900267e-05
## ASV0859      1.646178e-38  1.008136e-04  1.054603e-04  1.102364e-04
## ASV12971    -4.307029e-38 -2.686408e-04 -2.811692e-04 -2.941669e-04
## ASV16856    -4.307029e-38 -2.686408e-04 -2.811480e-04 -2.941438e-04
## ASV7321     -3.513345e-38 -2.194858e-04 -2.296870e-04 -2.403210e-04
## ASV8780     -4.307029e-38 -2.686407e-04 -2.811100e-04 -2.941024e-04
## ASV1569      3.172041e-38  1.968608e-04  2.059894e-04  2.154612e-04
## ASV3696      5.300945e-39  3.170304e-05  3.321207e-05  3.467750e-05
## ASV0624      5.823903e-38  3.601778e-04  3.769539e-04  3.942383e-04
## ASV0495      3.590085e-38  2.196109e-04  2.298681e-04  2.402786e-04
## ASV16971    -1.761531e-38 -1.097604e-04 -1.148405e-04 -1.201437e-04
## ASV6535      9.535005e-39  6.230118e-05  6.536808e-05  6.853862e-05
## ASV1897      4.203325e-38  2.577896e-04  2.697373e-04  2.819901e-04
## ASV2631     -4.658649e-39 -3.305485e-05 -3.476329e-05 -3.657832e-05
## ASV6204      1.368773e-38  8.641016e-05  9.052689e-05  9.476468e-05
## ASV3312     -2.647859e-38 -1.655328e-04 -1.732653e-04 -1.813006e-04
## ASV3360      1.640577e-38  1.046865e-04  1.097151e-04  1.149091e-04
## ASV3907      7.881744e-39  5.085462e-05  5.329517e-05  5.584468e-05
## ASV6090      8.337117e-39  5.234602e-05  5.486479e-05  5.741667e-05
## ASV8652     -1.007941e-38 -6.049137e-05 -6.322716e-05 -6.602966e-05
## ASV11129    -1.761531e-38 -1.086439e-04 -1.136612e-04 -1.188561e-04
## ASV11073    -1.761531e-38 -1.086439e-04 -1.136527e-04 -1.188469e-04
## ASV1840      5.907088e-38  3.635740e-04  3.804621e-04  3.978021e-04
## ASV2298      2.253527e-38  1.373399e-04  1.435990e-04  1.500772e-04
## ASV2420      5.218580e-38  3.255549e-04  3.408462e-04  3.566138e-04
## ASV6474      6.881894e-39  4.447268e-05  4.659975e-05  4.882952e-05
## ASV8475     -1.761531e-38 -1.086439e-04 -1.136414e-04 -1.188346e-04
## ASV8679     -1.761531e-38 -1.086439e-04 -1.136329e-04 -1.188254e-04
## ASV6527      1.636266e-38  1.033785e-04  1.082870e-04  1.133640e-04
## ASV2504     -2.342292e-39 -1.701805e-05 -1.805959e-05 -1.902135e-05
## ASV1093     -1.855121e-38 -1.151657e-04 -1.206555e-04 -1.262068e-04
## ASV0994      2.435005e-38  1.518091e-04  1.588878e-04  1.662320e-04
## ASV0092     -3.956158e-38 -2.502154e-04 -2.620735e-04 -2.743717e-04
## ASV2619      8.953795e-39  5.682656e-05  5.950699e-05  6.230727e-05
## ASV0121      5.274311e-38  3.169921e-04  3.315391e-04  3.462633e-04
## ASV0932      1.695377e-38  1.087630e-04  1.140434e-04  1.194699e-04
## ASV5229      2.968493e-38  1.819664e-04  1.904423e-04  1.990838e-04
## ASV6737      2.965703e-38  1.854651e-04  1.941825e-04  2.031863e-04
## ASV11213    -4.307029e-38 -2.617404e-04 -2.738407e-04 -2.861503e-04
## ASV1151      8.692754e-38  5.397372e-04  5.649492e-04  5.909473e-04
## ASV3813      4.616307e-38  2.819419e-04  2.950099e-04  3.083429e-04
## ASV5566      8.269295e-39  5.835884e-05  6.123636e-05  6.441439e-05
## ASV7529     -4.307029e-38 -2.617404e-04 -2.738094e-04 -2.861171e-04
## ASV2193      5.998846e-38  3.774299e-04  3.951882e-04  4.136305e-04
## ASV2349      5.562478e-38  3.470905e-04  3.633022e-04  3.801135e-04
## ASV2387      5.028924e-38  3.048239e-04  3.188197e-04  3.331089e-04
## ASV2699      3.988293e-38  2.535973e-04  2.656059e-04  2.781403e-04
## ASV3353      5.360171e-38  3.309599e-04  3.463798e-04  3.622217e-04
## ASV3621      2.915574e-38  1.762725e-04  1.843890e-04  1.926314e-04
## ASV3848      4.837844e-39  3.128401e-05  3.276725e-05  3.434004e-05
## ASV4440     -6.352699e-41  4.050718e-06  4.405358e-06  4.837522e-06
## ASV4751      5.590983e-38  3.488976e-04  3.652461e-04  3.821470e-04
## ASV5115      2.366276e-38  1.495516e-04  1.565516e-04  1.638856e-04
## ASV5850     -4.307029e-38 -2.617404e-04 -2.737556e-04 -2.860594e-04
## ASV6293      2.597579e-38  1.618460e-04  1.694300e-04  1.772549e-04
## ASV6513      1.071533e-38  7.121434e-05  7.468335e-05  7.836314e-05
## ASV7628     -4.307029e-38 -2.617403e-04 -2.737388e-04 -2.860415e-04
## ASV7658      2.525182e-38  1.598704e-04  1.674603e-04  1.753190e-04
## ASV0776     -5.032782e-38 -3.078551e-04 -3.221308e-04 -3.367132e-04
## ASV10227    -4.307029e-38 -2.617403e-04 -2.737206e-04 -2.860220e-04
## ASV11965    -4.307029e-38 -2.617403e-04 -2.737004e-04 -2.860002e-04
## ASV1270     -1.490230e-38 -8.860726e-05 -9.257232e-05 -9.662802e-05
## ASV13123    -3.272211e-38 -1.976928e-04 -2.066335e-04 -2.158574e-04
## ASV5828      4.307029e-38  2.617402e-04  2.736608e-04  2.859574e-04
## ASV5920     -4.307029e-38 -2.617402e-04 -2.736406e-04 -2.859357e-04
## ASV6071      3.957039e-38  2.486370e-04  2.603211e-04  2.724560e-04
## ASV6723     -2.495385e-39 -1.253460e-05 -1.295282e-05 -1.339546e-05
## ASV6727     -4.307029e-38 -2.617402e-04 -2.736154e-04 -2.859083e-04
## ASV7759     -4.307029e-38 -2.617402e-04 -2.735954e-04 -2.858865e-04
## ASV0733      2.834952e-39  1.855604e-05  1.931494e-05  2.025628e-05
## ASV1655     -5.682449e-39 -3.967576e-05 -4.158858e-05 -4.372861e-05
## ASV0755     -6.353015e-38 -3.894472e-04 -4.073588e-04 -4.258463e-04
## ASV0796      2.692328e-38  1.585093e-04  1.656820e-04  1.728670e-04
## ASV0878      5.441067e-38  3.375729e-04  3.533016e-04  3.695438e-04
## ASV4988     -3.372883e-38 -2.095773e-04 -2.193236e-04 -2.294220e-04
## ASV0083     -3.793139e-38 -2.393064e-04 -2.504600e-04 -2.621694e-04
## ASV0273      1.920534e-38  1.125401e-04  1.176782e-04  1.227633e-04
## ASV3076      1.240580e-38  7.870319e-05  8.242472e-05  8.630384e-05
## ASV1513      1.050208e-38  6.458104e-05  6.758700e-05  7.066383e-05
## ASV5159     -2.985012e-39 -1.624088e-05 -1.700274e-05 -1.767171e-05
## ASV3422     -2.540820e-38 -1.594330e-04 -1.669272e-04 -1.746972e-04
## ASV12230    -3.949073e-39 -2.278930e-05 -2.378149e-05 -2.478661e-05
## ASV1694      5.402647e-38  3.295663e-04  3.450061e-04  3.605946e-04
## ASV1249      2.316279e-38  1.443687e-04  1.513080e-04  1.583013e-04
## ASV1697     -1.306938e-38 -7.987341e-05 -8.354261e-05 -8.732182e-05
## ASV4408     -3.326927e-38 -1.956375e-04 -2.045538e-04 -2.134221e-04
## ASV0095     -3.882255e-38 -2.467145e-04 -2.584385e-04 -2.706264e-04
## ASV0410      5.776032e-40  7.492326e-07  7.988490e-07  6.887258e-07
## ASV4642     -4.938669e-38 -3.083709e-04 -3.228478e-04 -3.377948e-04
## ASV4560     -6.902655e-40 -1.285875e-06 -1.227690e-06 -1.127655e-06
## ASV7586     -2.315701e-38 -1.453020e-04 -1.521121e-04 -1.591888e-04
## ASV4144     -2.590330e-38 -1.634479e-04 -1.711942e-04 -1.792094e-04
## ASV0327     -2.868261e-38 -1.772832e-04 -1.854689e-04 -1.939592e-04
## ASV0946     -2.519712e-38 -1.495930e-04 -1.562495e-04 -1.630983e-04
## ASV3254     -3.040027e-38 -1.915048e-04 -2.005474e-04 -2.099193e-04
## ASV0349      4.421535e-38  2.765811e-04  2.895279e-04  3.029543e-04
## ASV0472     -2.726909e-38 -1.686451e-04 -1.764404e-04 -1.845216e-04
## ASV1330      2.820047e-38  1.697962e-04  1.775103e-04  1.854038e-04
## ASV2605      2.879268e-38  1.801422e-04  1.886077e-04  1.973548e-04
## ASV2846     -1.596366e-38 -1.028551e-04 -1.078198e-04 -1.129749e-04
## ASV3982     -1.316464e-38 -8.376402e-05 -8.776630e-05 -9.191283e-05
## ASV4116     -3.040027e-38 -1.915048e-04 -2.005206e-04 -2.098901e-04
## ASV6048     -1.771592e-38 -1.121393e-04 -1.174240e-04 -1.229382e-04
## ASV1146      3.722078e-38  2.311775e-04  2.419642e-04  2.530975e-04
## ASV13362     2.410474e-39  1.354106e-05  1.411190e-05  1.468593e-05
## ASV1422     -3.040027e-38 -1.915048e-04 -2.005008e-04 -2.098684e-04
## ASV3640     -3.040027e-38 -1.915048e-04 -2.004855e-04 -2.098518e-04
## ASV5404      2.487178e-38  1.501311e-04  1.569513e-04  1.639555e-04
## ASV6118     -3.040027e-38 -1.915048e-04 -2.004754e-04 -2.098406e-04
## ASV1115     -2.592496e-38 -1.633836e-04 -1.711208e-04 -1.791181e-04
## ASV0888     -5.620737e-38 -3.499158e-04 -3.662958e-04 -3.832004e-04
## ASV4620      9.189096e-39  4.593700e-05  4.765461e-05  4.928630e-05
## ASV3099      1.058778e-38  6.874081e-05  7.207765e-05  7.554987e-05
## ASV7099      4.881364e-39  3.195980e-05  3.349444e-05  3.511961e-05
## ASV5892     -3.530855e-38 -2.203287e-04 -2.306167e-04 -2.412852e-04
## ASV6978     -3.485570e-38 -2.193499e-04 -2.296534e-04 -2.403764e-04
## ASV6555     -1.067276e-38 -7.435287e-05 -7.807952e-05 -8.208802e-05
## ASV0539     -4.482517e-38 -2.765803e-04 -2.894454e-04 -3.026766e-04
## ASV4665      1.324299e-38  7.772118e-05  8.109831e-05  8.459836e-05
## ASV2210      2.825782e-38  1.667676e-04  1.742252e-04  1.818285e-04
## ASV1329      2.770622e-38  1.747183e-04  1.829891e-04  1.915458e-04
## ASV7123     -4.034530e-38 -2.536486e-04 -2.655947e-04 -2.779841e-04
## ASV1260      1.515010e-40  1.602765e-06  1.736959e-06  1.851800e-06
## ASV1011      4.056037e-38  2.587658e-04  2.711650e-04  2.840026e-04
## ASV4233      1.112053e-38  7.075386e-05  7.416436e-05  7.766654e-05
## ASV1475      4.274011e-38  2.634608e-04  2.757043e-04  2.883067e-04
## ASV6099     -4.940898e-38 -3.051499e-04 -3.192425e-04 -3.338461e-04
## ASV1428     -1.827989e-39  1.212189e-06  1.570192e-06  2.284201e-06
## ASV5101     -5.283484e-38 -3.343444e-04 -3.501364e-04 -3.665826e-04
## ASV11827    -2.412558e-38 -1.508786e-04 -1.579247e-04 -1.652479e-04
## ASV13899    -2.744962e-38 -1.715828e-04 -1.795753e-04 -1.878971e-04
## ASV21259    -3.208564e-38 -2.014207e-04 -2.108433e-04 -2.206607e-04
## ASV6635     -1.557054e-38 -9.955787e-05 -1.042202e-04 -1.091644e-04
## ASV9922     -4.307029e-38 -2.700159e-04 -2.826081e-04 -2.957450e-04
## ASV2869      5.465388e-39  3.326308e-05  3.476409e-05  3.632420e-05
## ASV1740      2.859320e-38  1.764195e-04  1.845273e-04  1.929586e-04
## ASV4406     -4.307029e-38 -2.719506e-04 -2.847638e-04 -2.981074e-04
## ASV5586     -3.647324e-38 -2.318716e-04 -2.428273e-04 -2.542855e-04
## ASV3255     -1.485802e-38 -9.211569e-05 -9.636501e-05 -1.007923e-04
## ASV12281    -2.116552e-38 -1.292840e-04 -1.352353e-04 -1.413533e-04
## ASV5388     -4.200144e-38 -2.550696e-04 -2.665704e-04 -2.785347e-04
## ASV17660    -4.183487e-38 -2.614306e-04 -2.737171e-04 -2.864016e-04
## ASV0159      2.400975e-38  1.438752e-04  1.507596e-04  1.574572e-04
## ASV2734     -6.251970e-38 -3.877501e-04 -4.058624e-04 -4.245194e-04
## ASV2049      4.712326e-39  2.943501e-05  3.087015e-05  3.230364e-05
## ASV2465      3.938409e-39  1.907255e-05  1.968556e-05  2.031965e-05
## ASV2147      2.099095e-38  1.210422e-04  1.262450e-04  1.315869e-04
## ASV3113     -6.098769e-39 -3.738119e-05 -3.912354e-05 -4.089480e-05
## ASV0622     -4.377638e-38 -2.747271e-04 -2.877075e-04 -3.010969e-04
## ASV0437     -4.440115e-38 -2.756528e-04 -2.885066e-04 -3.017793e-04
## ASV6385     -4.813332e-38 -3.013249e-04 -3.154880e-04 -3.301351e-04
## ASV3699     -4.307029e-38 -2.733004e-04 -2.862104e-04 -2.996905e-04
## ASV2208      4.307029e-38  2.733004e-04  2.861885e-04  2.996665e-04
## ASV1053      1.007388e-38  6.256372e-05  6.541281e-05  6.842454e-05
## ASV8468     -1.004395e-38 -6.131065e-05 -6.408141e-05 -6.697446e-05
## ASV0951     -3.714148e-38 -2.293420e-04 -2.402073e-04 -2.512004e-04
## ASV0278      5.376201e-38  3.284969e-04  3.435463e-04  3.590807e-04
## ASV0914     -2.767334e-38 -1.715913e-04 -1.796734e-04 -1.879289e-04
## ASV0737      4.307029e-38  2.566249e-04  2.685069e-04  2.803226e-04
## ASV2038      6.043088e-38  3.703824e-04  3.876006e-04  4.051915e-04
## ASV2171      3.803113e-38  2.253047e-04  2.356980e-04  2.460023e-04
## ASV2607      4.307029e-38  2.566248e-04  2.684603e-04  2.802737e-04
## ASV3143      3.311421e-38  1.949402e-04  2.038840e-04  2.127327e-04
## ASV3187     -4.610563e-38 -2.753502e-04 -2.880153e-04 -3.007228e-04
## ASV3810      4.307029e-38  2.566247e-04  2.684046e-04  2.802155e-04
## ASV5060     -2.692454e-38 -1.580480e-04 -1.652757e-04 -1.724264e-04
## ASV5325      4.307029e-38  2.566246e-04  2.683737e-04  2.801831e-04
## ASV6905     -4.307029e-38 -2.566245e-04 -2.683539e-04 -2.801623e-04
## ASV7597     -4.307029e-38 -2.566245e-04 -2.683341e-04 -2.801414e-04
## ASV9652     -4.307029e-38 -2.566244e-04 -2.683144e-04 -2.801205e-04
## ASV2634      4.307029e-38  2.566244e-04  2.682947e-04  2.800997e-04
## ASV3065      4.307029e-38  2.566243e-04  2.682750e-04  2.800788e-04
## ASV3331      4.307029e-38  2.566243e-04  2.682554e-04  2.800580e-04
## ASV7434     -4.307029e-38 -2.566242e-04 -2.682358e-04 -2.800371e-04
## ASV7720      5.262120e-39  4.061806e-05  4.279078e-05  4.516286e-05
## ASV8414     -4.307029e-38 -2.566241e-04 -2.682181e-04 -2.800183e-04
## ASV12139    -4.307029e-38 -2.566241e-04 -2.681985e-04 -2.799975e-04
## ASV1824      4.202166e-38  2.501149e-04  2.613643e-04  2.728484e-04
## ASV2094      4.253947e-38  2.534159e-04  2.648057e-04  2.764522e-04
## ASV2770     -8.408167e-39 -5.783772e-05 -6.073838e-05 -6.381598e-05
## ASV3505     -2.190723e-38 -1.243465e-04 -1.296736e-04 -1.350483e-04
## ASV1935      4.307029e-38  2.566239e-04  2.681353e-04  2.799299e-04
## ASV5764     -4.307029e-38 -2.566238e-04 -2.681159e-04 -2.799091e-04
## ASV6806      2.558184e-38  1.629887e-04  1.707455e-04  1.788156e-04
## ASV6942     -4.307029e-38 -2.566238e-04 -2.680979e-04 -2.798897e-04
## ASV1166      4.710626e-38  2.819594e-04  2.946021e-04  3.076267e-04
## ASV1664      3.290420e-38  2.000743e-04  2.092931e-04  2.187048e-04
## ASV2568      4.307029e-38  2.566237e-04  2.680606e-04  2.798495e-04
## ASV3525      4.307029e-38  2.566236e-04  2.680414e-04  2.798287e-04
## ASV4965     -5.043521e-38 -3.065292e-04 -3.205224e-04 -3.349348e-04
## ASV6607     -2.751995e-38 -1.591944e-04 -1.660156e-04 -1.730600e-04
## ASV7187      1.411339e-38  8.663972e-05  9.075806e-05  9.488278e-05
## ASV0388     -3.960348e-38 -2.526750e-04 -2.646906e-04 -2.772245e-04
## ASV1420      3.510812e-54  1.571938e-06  1.691733e-06  1.848604e-06
## ASV14293     1.257258e-38  8.194753e-05  8.587536e-05  9.002686e-05
## ASV17785     3.510812e-54  1.571939e-06  1.685477e-06  1.841612e-06
## ASV7678      3.797204e-39  1.642073e-05  1.695047e-05  1.736866e-05
## ASV2253      1.063109e-38  6.912819e-05  7.246707e-05  7.596185e-05
## ASV4150      2.316890e-38  1.396698e-04  1.460753e-04  1.525896e-04
## ASV3836     -5.193631e-38 -3.221550e-04 -3.371378e-04 -3.526384e-04
## ASV16231    -4.180607e-38 -2.638532e-04 -2.762759e-04 -2.892153e-04
## ASV2730      8.527633e-40  5.292177e-06  5.574844e-06  5.833435e-06
## ASV2072      2.542236e-38  1.508206e-04  1.574834e-04  1.643750e-04
## ASV2160      5.778867e-39  3.975964e-05  4.175870e-05  4.388312e-05
## ASV5013      8.554903e-39  4.936533e-05  5.156648e-05  5.374217e-05
## ASV2586      1.430819e-38  8.802629e-05  9.213416e-05  9.632767e-05
## ASV1442      1.097388e-38  6.892946e-05  7.218801e-05  7.554119e-05
## ASV3101      1.706056e-38  9.900269e-05  1.033397e-04  1.077368e-04
## ASV3323     -1.268229e-38 -8.179955e-05 -8.572360e-05 -8.978671e-05
## ASV1812      4.250432e-38  2.531091e-04  2.643193e-04  2.759337e-04
## ASV6120     -4.295281e-39 -2.955501e-05 -3.095996e-05 -3.253172e-05
## ASV2565      9.308136e-39  5.521255e-05  5.769090e-05  6.021663e-05
## ASV6687      4.647897e-39  2.823550e-05  2.959676e-05  3.092824e-05
## ASV5357     -3.544703e-38 -2.205527e-04 -2.307887e-04 -2.414284e-04
## ASV9383      1.822722e-38  1.099564e-04  1.149650e-04  1.200939e-04
## ASV11753    -3.040027e-38 -1.888235e-04 -1.975497e-04 -2.066403e-04
## ASV11512    -8.443889e-39 -5.244308e-05 -5.478460e-05 -5.730400e-05
## ASV2791     -1.001107e-39 -8.135342e-06 -8.525973e-06 -9.015298e-06
## ASV0664     -6.462177e-38 -3.993651e-04 -4.179315e-04 -4.370636e-04
## ASV3436      5.808385e-39  4.069525e-05  4.276957e-05  4.498399e-05
## ASV5755      4.420510e-38  2.720176e-04  2.846754e-04  2.976481e-04
## ASV10970    -4.307029e-38 -2.673211e-04 -2.797787e-04 -2.926449e-04
## ASV11798    -2.199585e-38 -1.364456e-04 -1.427585e-04 -1.493189e-04
## ASV18193    -4.307029e-38 -2.673211e-04 -2.797484e-04 -2.926120e-04
## ASV2548      4.604562e-38  2.816031e-04  2.945793e-04  3.079195e-04
## ASV3901      4.976453e-38  3.043360e-04  3.183977e-04  3.328187e-04
## ASV5197      1.984404e-39  6.046621e-06  6.059893e-06  6.028077e-06
## ASV5859      2.205638e-38  1.351086e-04  1.413163e-04  1.477291e-04
## ASV6240     -4.307029e-38 -2.673211e-04 -2.797364e-04 -2.925990e-04
## ASV7281      4.307029e-38  2.673211e-04  2.797154e-04  2.925761e-04
## ASV7635      2.394249e-38  1.499143e-04  1.570449e-04  1.643373e-04
## ASV8822     -4.307029e-38 -2.673211e-04 -2.796986e-04 -2.925578e-04
## ASV4810     -9.716380e-39 -5.718307e-05 -5.967421e-05 -6.225001e-05
## ASV5308      4.502545e-38  2.796865e-04  2.926489e-04  3.061183e-04
## ASV2749     -4.899388e-38 -3.059635e-04 -3.203243e-04 -3.351561e-04
## ASV0298      2.639139e-39  2.279277e-05  2.402761e-05  2.546266e-05
## ASV2597     -4.580768e-38 -2.868280e-04 -3.002843e-04 -3.142269e-04
## ASV5758     -1.920718e-38 -1.195607e-04 -1.251098e-04 -1.308836e-04
## ASV9987     -4.866217e-38 -3.032334e-04 -3.174747e-04 -3.321428e-04
## ASV0971      1.099668e-38  6.205989e-05  6.463759e-05  6.731508e-05
## ASV0627     -4.718140e-38 -2.958515e-04 -3.097660e-04 -3.241716e-04
## ASV1758      4.324426e-38  2.683308e-04  2.808738e-04  2.937922e-04
## ASV4559      3.105208e-41  1.040685e-06  1.142798e-06  1.236422e-06
## ASV11400    -2.171883e-39 -1.139180e-05 -1.181606e-05 -1.224791e-05
## ASV11559    -4.307029e-38 -2.696797e-04 -2.822674e-04 -2.953731e-04
## ASV3943     -4.307029e-38 -2.696797e-04 -2.822461e-04 -2.953498e-04
## ASV10389     8.575378e-39  5.071946e-05  5.301688e-05  5.532375e-05
## ASV5168      3.935741e-38  2.391267e-04  2.500863e-04  2.613262e-04
## ASV5724      2.652547e-38  1.663954e-04  1.742016e-04  1.823027e-04
## ASV6337      9.187161e-39  5.280600e-05  5.515180e-05  5.747095e-05
## ASV11063     2.537146e-38  1.515844e-04  1.583691e-04  1.653541e-04
## ASV4279     -4.630236e-39 -2.878385e-05 -3.012631e-05 -3.151450e-05
## ASV7660     -1.761531e-38 -1.115776e-04 -1.168582e-04 -1.223520e-04
## ASV8218     -1.761531e-38 -1.115776e-04 -1.168492e-04 -1.223422e-04
## ASV3574      6.944116e-38  4.378850e-04  4.585138e-04  4.799633e-04
## ASV12050    -1.761531e-38 -1.115776e-04 -1.168509e-04 -1.223441e-04
## ASV3897      1.656826e-38  1.002116e-04  1.047675e-04  1.094538e-04
## ASV3856     -5.419528e-38 -3.370846e-04 -3.527198e-04 -3.689691e-04
## ASV3024     -1.626094e-38 -1.060031e-04 -1.111534e-04 -1.165177e-04
## ASV8715     -4.213741e-38 -2.620844e-04 -2.743586e-04 -2.870088e-04
## ASV6917     -1.897001e-38 -1.110731e-04 -1.165698e-04 -1.215956e-04
## ASV1132      4.288932e-38  2.709730e-04  2.837071e-04  2.970075e-04
## ASV3583      2.137766e-38  1.361746e-04  1.426156e-04  1.493593e-04
## ASV0328      6.940724e-38  4.328533e-04  4.530647e-04  4.740162e-04
## ASV0915     -2.286033e-38 -1.449221e-04 -1.517378e-04 -1.588775e-04
## ASV2677      2.287369e-38  1.464084e-04  1.534013e-04  1.606870e-04
## ASV0599      2.437626e-38  1.484958e-04  1.555472e-04  1.625706e-04
## ASV0283     -6.365478e-38 -3.948659e-04 -4.132492e-04 -4.322484e-04
## ASV1028      2.574698e-38  1.631557e-04  1.708550e-04  1.788878e-04
## ASV0523      4.734915e-38  2.973444e-04  3.113586e-04  3.258603e-04
## ASV8201     -2.876728e-38 -1.812237e-04 -1.897037e-04 -1.985604e-04
## ASV2795     -9.235616e-39 -5.702945e-05 -5.961095e-05 -6.233767e-05
## ASV3563     -9.221702e-39 -5.694375e-05 -5.951687e-05 -6.223902e-05
## ASV1553     -1.754869e-38 -1.041521e-04 -1.088412e-04 -1.136111e-04
## ASV7155     -3.487376e-39 -2.817697e-05 -2.987657e-05 -3.156561e-05
## ASV0365      6.180454e-38  3.813607e-04  3.988929e-04  4.171273e-04
## ASV8583     -4.243646e-38 -2.619264e-04 -2.742137e-04 -2.867546e-04
## ASV5400      2.085204e-39  1.376740e-05  1.451267e-05  1.521995e-05
## ASV5908      3.356348e-38  2.031431e-04  2.123831e-04  2.218824e-04
## ASV2075      1.818949e-38  1.145834e-04  1.199031e-04  1.255022e-04
## ASV2520     -3.626775e-38 -2.283956e-04 -2.391601e-04 -2.503346e-04
## ASV9596     -1.877930e-38 -1.127992e-04 -1.179923e-04 -1.232304e-04
## ASV1131     -6.844056e-39 -3.793478e-05 -3.964728e-05 -4.124734e-05
## ASV0579     -1.208585e-38 -7.442018e-05 -7.792005e-05 -8.147643e-05
## ASV0288     -5.926669e-38 -3.643685e-04 -3.812712e-04 -3.986319e-04
## ASV4053      1.077875e-38  6.080044e-05  6.327282e-05  6.587280e-05
## ASV1736     -3.131613e-38 -1.944688e-04 -2.034869e-04 -2.128489e-04
## ASV1254      3.310807e-38  2.006146e-04  2.098590e-04  2.192681e-04
## ASV9038     -5.084157e-38 -3.180228e-04 -3.328625e-04 -3.482917e-04
## ASV4746      4.588977e-38  2.897996e-04  3.034826e-04  3.177054e-04
## ASV5803      1.761531e-38  1.100535e-04  1.151690e-04  1.205039e-04
## ASV0525      1.929316e-39  1.258201e-05  1.318450e-05  1.382279e-05
## ASV1974      2.791714e-38  1.682534e-04  1.759421e-04  1.837762e-04
## ASV1827      4.617373e-38  2.816133e-04  2.945775e-04  3.078740e-04
## ASV30780     2.561976e-39  1.396504e-05  1.457628e-05  1.514489e-05
## ASV9342      1.273144e-39  1.014228e-05  1.071326e-05  1.132423e-05
## ASV21626    -4.298399e-38 -2.658886e-04 -2.782786e-04 -2.910282e-04
## ASV1232     -3.066290e-38 -1.881926e-04 -1.969545e-04 -2.059084e-04
## ASV5578     -3.040027e-38 -1.898392e-04 -1.986837e-04 -2.078813e-04
## ASV5868      3.312771e-38  2.000335e-04  2.091247e-04  2.184663e-04
## ASV13625    -1.350441e-38 -8.275524e-05 -8.653603e-05 -9.045893e-05
## ASV3614      5.417200e-39  3.094305e-05  3.227311e-05  3.362155e-05
## ASV2128      2.723657e-38  1.713525e-04  1.794265e-04  1.877972e-04
## ASV5086      6.196260e-39  3.759036e-05  3.933144e-05  4.109395e-05
## ASV6614     -3.040027e-38 -1.898392e-04 -1.986755e-04 -2.078722e-04
## ASV9451     -3.040027e-38 -1.898392e-04 -1.986606e-04 -2.078559e-04
## ASV9533     -3.040027e-38 -1.898392e-04 -1.986457e-04 -2.078396e-04
## ASV10697    -9.830274e-53  2.142690e-06  2.322016e-06  2.539594e-06
## ASV1473     -1.496456e-38 -8.943462e-05 -9.343839e-05 -9.755951e-05
## ASV1414     -8.822413e-39 -5.618440e-05 -5.885656e-05 -6.162953e-05
## ASV1567     -8.185222e-39 -5.485370e-05 -5.749020e-05 -6.034675e-05
## ASV6395     -3.040027e-38 -1.912331e-04 -2.001939e-04 -2.095365e-04
## ASV2366      1.339779e-38  7.753935e-05  8.099022e-05  8.442544e-05
## ASV2537      1.318291e-38  7.725440e-05  8.071067e-05  8.419095e-05
## ASV5378     -3.040027e-38 -1.912332e-04 -2.001870e-04 -2.095286e-04
## ASV5929     -3.202008e-38 -2.012905e-04 -2.106992e-04 -2.205236e-04
## ASV6360      2.635489e-38  1.602062e-04  1.676351e-04  1.751704e-04
## ASV7916     -4.739203e-39 -3.220451e-05 -3.375684e-05 -3.545780e-05
## ASV13322     9.764211e-39  6.323345e-05  6.632212e-05  6.951105e-05
## ASV6207     -3.894442e-38 -2.421832e-04 -2.535072e-04 -2.651914e-04
## ASV8823     -3.083163e-38 -1.926707e-04 -2.016960e-04 -2.110404e-04
## ASV1379      4.307029e-38  2.682660e-04  2.807871e-04  2.937494e-04
## ASV3259     -4.307029e-38 -2.682660e-04 -2.807659e-04 -2.937264e-04
## ASV18748    -2.516290e-40  5.358788e-07  6.188262e-07  7.574088e-07
## ASV3570      9.265570e-39  5.821350e-05  6.099739e-05  6.384047e-05
## ASV0790     -1.112853e-38 -5.917191e-05 -6.149310e-05 -6.382420e-05
## ASV5149     -3.967337e-38 -2.452704e-04 -2.567303e-04 -2.684885e-04
## ASV1730     -4.079650e-38 -2.531622e-04 -2.649017e-04 -2.770802e-04
## ASV3488     -3.569086e-39 -2.091876e-05 -2.182091e-05 -2.276232e-05
## ASV5486     -4.307029e-38 -2.736626e-04 -2.865885e-04 -3.001064e-04
## ASV1319      8.796519e-39  4.441138e-05  4.613950e-05  4.775209e-05
## ASV15328    -3.040027e-38 -1.887361e-04 -1.975018e-04 -2.065888e-04
## ASV5994      4.376886e-38  2.724649e-04  2.851265e-04  2.982794e-04
## ASV4992     -3.727257e-39 -2.199804e-05 -2.298550e-05 -2.398390e-05
## ASV1788     -4.942839e-38 -2.988260e-04 -3.123858e-04 -3.263515e-04
## ASV3264     -1.094285e-39 -3.826389e-06 -3.871103e-06 -3.894058e-06
## ASV4895      2.304876e-39  1.296494e-05  1.352914e-05  1.408196e-05
## ASV9218     -1.341633e-39 -5.197697e-06 -5.277566e-06 -5.356211e-06
## ASV0736     -3.896382e-40 -5.372918e-06 -5.755406e-06 -6.173760e-06
## ASV0916      3.040027e-38  1.887360e-04  1.974657e-04  2.065496e-04
## ASV15761    -3.040027e-38 -1.887360e-04 -1.974509e-04 -2.065335e-04
## ASV4191      3.856746e-38  2.356273e-04  2.464337e-04  2.575757e-04
## ASV3268     -8.218848e-39 -4.852314e-05 -5.070820e-05 -5.291050e-05
## ASV15321    -4.457664e-39 -3.042370e-05 -3.191186e-05 -3.352344e-05
## ASV0708     -2.983608e-38 -1.881266e-04 -1.969934e-04 -2.062095e-04
## ASV4100      4.016963e-39  2.248101e-05  2.350198e-05  2.445891e-05
## ASV1627      2.603563e-38  1.526413e-04  1.593978e-04  1.662919e-04
## ASV7045     -2.671559e-38 -1.667436e-04 -1.746196e-04 -1.826950e-04
## ASV3271      7.978757e-39  4.109493e-05  4.264479e-05  4.420384e-05
## ASV6200     -4.478342e-39 -2.890118e-05 -3.029555e-05 -3.175110e-05
## ASV2727     -3.060995e-38 -1.962402e-04 -2.056570e-04 -2.154359e-04
## ASV3523     -4.219612e-38 -2.609672e-04 -2.731953e-04 -2.857142e-04
## ASV2259      2.832814e-38  1.760919e-04  1.842892e-04  1.927814e-04
## ASV0181      4.209740e-38  2.590859e-04  2.710705e-04  2.834265e-04
## ASV1680      8.363405e-38  5.184930e-04  5.426521e-04  5.675797e-04
## ASV0176      8.920378e-39  5.302650e-05  5.543215e-05  5.785994e-05
## ASV10458    -3.040027e-38 -1.893357e-04 -1.981811e-04 -2.073317e-04
## ASV10658    -3.040027e-38 -1.893357e-04 -1.981661e-04 -2.073155e-04
## ASV16807    -3.040027e-38 -1.893357e-04 -1.981512e-04 -2.072992e-04
## ASV2113     -3.040027e-38 -1.893357e-04 -1.981362e-04 -2.072830e-04
## ASV2403      3.158448e-38  1.944613e-04  2.034296e-04  2.127019e-04
## ASV2484     -3.040027e-38 -1.893357e-04 -1.981301e-04 -2.072763e-04
## ASV8876     -3.040027e-38 -1.893357e-04 -1.981152e-04 -2.072600e-04
## ASV0386      4.388575e-38  2.765242e-04  2.894985e-04  3.030290e-04
## ASV0351      1.266892e-38  7.673294e-05  8.016972e-05  8.375475e-05
## ASV4942     -1.743414e-38 -1.080154e-04 -1.129479e-04 -1.181334e-04
## ASV5128     -1.323837e-38 -8.351455e-05 -8.738527e-05 -9.146967e-05
## ASV3496      1.425058e-38  9.317875e-05  9.774039e-05  1.024865e-04
## ASV3329      4.379282e-38  2.752929e-04  2.882441e-04  3.016823e-04
## ASV7878     -3.040027e-38 -1.887802e-04 -1.975017e-04 -2.065870e-04
## ASV8251     -1.154975e-38 -7.172883e-05 -7.503126e-05 -7.848119e-05
## ASV15958    -9.834646e-39 -6.191819e-05 -6.476432e-05 -6.778501e-05
## ASV7972     -4.307029e-38 -2.695357e-04 -2.821526e-04 -2.952441e-04
## ASV2088      4.307029e-38  2.695357e-04  2.821312e-04  2.952209e-04
## ASV3054     -2.025664e-38 -1.268731e-04 -1.327936e-04 -1.389577e-04
## ASV4494     -4.307029e-38 -2.695356e-04 -2.821014e-04 -2.951884e-04
## ASV0087     -8.251085e-38 -5.114485e-04 -5.351609e-04 -5.597362e-04
## ASV1614     -3.377745e-38 -2.090453e-04 -2.188218e-04 -2.288547e-04
## ASV3037     -1.860880e-38 -1.156838e-04 -1.211680e-04 -1.267522e-04
## ASV6615     -4.386457e-39 -3.000699e-05 -3.150718e-05 -3.309968e-05
## ASV1027      1.283109e-38  7.861818e-05  8.221562e-05  8.594156e-05
## ASV2754     -7.320234e-39 -4.861193e-05 -5.095812e-05 -5.346544e-05
## ASV0536     -5.846963e-39 -3.803016e-05 -3.986596e-05 -4.178872e-05
## ASV2318     -1.270832e-38 -8.081064e-05 -8.461129e-05 -8.860534e-05
## ASV5954      2.687102e-38  1.615541e-04  1.688707e-04  1.763737e-04
## ASV9028      1.812002e-38  1.131930e-04  1.184980e-04  1.239845e-04
## ASV6600     -3.040027e-38 -1.913244e-04 -2.002746e-04 -2.096233e-04
## ASV1923     -8.299008e-39 -5.060743e-05 -5.289302e-05 -5.527586e-05
## ASV4034     -5.193104e-39 -3.659515e-05 -3.837241e-05 -4.036075e-05
## ASV9933     -3.040027e-38 -1.913244e-04 -2.002536e-04 -2.096002e-04
## ASV1575      6.183101e-39  3.617776e-05  3.777376e-05  3.940393e-05
## ASV7812     -5.242834e-38 -3.255313e-04 -3.407992e-04 -3.564817e-04
## ASV0515      3.451993e-38  2.102899e-04  2.198116e-04  2.297123e-04
## ASV1149     -2.771597e-39 -2.305398e-05 -2.433826e-05 -2.575517e-05
## ASV3791      1.368968e-38  8.737430e-05  9.144770e-05  9.577789e-05
## ASV4065     -4.893616e-38 -3.045635e-04 -3.186988e-04 -3.333920e-04
## ASV10631    -2.299719e-39 -1.694528e-05 -1.778915e-05 -1.874780e-05
## ASV2359     -5.026041e-38 -3.022999e-04 -3.159939e-04 -3.300455e-04
## ASV3206     -3.040027e-38 -1.894545e-04 -1.983158e-04 -2.074803e-04
## ASV4415      2.472808e-38  1.542281e-04  1.614286e-04  1.688886e-04
## ASV4467     -2.202237e-38 -1.359572e-04 -1.422701e-04 -1.487774e-04
## ASV5598      3.638726e-38  2.316995e-04  2.426944e-04  2.541673e-04
## ASV5910     -3.348159e-38 -2.089999e-04 -2.187602e-04 -2.288859e-04
## ASV9494     -3.040027e-38 -1.894545e-04 -1.982750e-04 -2.074360e-04
## ASV6548     -2.491846e-38 -1.547976e-04 -1.619703e-04 -1.694279e-04
## ASV8669     -3.040027e-38 -1.894545e-04 -1.982481e-04 -2.074067e-04
## ASV0674      1.962709e-38  1.182687e-04  1.236345e-04  1.291353e-04
## ASV0061     -7.184781e-39 -5.551956e-05 -5.845965e-05 -6.169586e-05
## ASV0310     -1.948525e-38 -1.177283e-04 -1.229651e-04 -1.284775e-04
## ASV0582      6.454997e-39  3.657020e-05  3.815041e-05  3.973084e-05
## ASV0739      5.695466e-38  3.584909e-04  3.753339e-04  3.928513e-04
## ASV1557      2.335143e-38  1.493822e-04  1.565115e-04  1.639436e-04
## ASV0146      5.568066e-38  3.363176e-04  3.517397e-04  3.674502e-04
## ASV3832      5.599303e-38  3.429288e-04  3.587704e-04  3.750328e-04
## ASV0734      1.204715e-38  7.634825e-05  8.001990e-05  8.377865e-05
## ASV3036     -3.978679e-38 -2.504909e-04 -2.623008e-04 -2.745547e-04
## ASV0240      1.104614e-38  6.756115e-05  7.068404e-05  7.388423e-05
## ASV2513     -6.119988e-38 -3.768651e-04 -3.944353e-04 -4.124281e-04
## ASV1118     -1.556208e-38 -9.982888e-05 -1.046814e-04 -1.096613e-04
## ASV7286     -3.040027e-38 -1.889275e-04 -1.977866e-04 -2.068996e-04
## ASV1077      4.127605e-38  2.528604e-04  2.645439e-04  2.765451e-04
## ASV1255     -3.040027e-38 -1.889274e-04 -1.977543e-04 -2.068648e-04
## ASV1794     -1.742954e-39 -1.142341e-05 -1.193942e-05 -1.251656e-05
## ASV2439     -3.040027e-38 -1.889274e-04 -1.977400e-04 -2.068493e-04
## ASV2467     -3.040027e-38 -1.889274e-04 -1.977251e-04 -2.068331e-04
## ASV3346     -3.040027e-38 -1.889274e-04 -1.977102e-04 -2.068170e-04
## ASV3973     -3.040027e-38 -1.889274e-04 -1.976954e-04 -2.068008e-04
## ASV4521      1.367489e-38  8.362637e-05  8.748065e-05  9.143482e-05
## ASV1909     -3.534639e-38 -2.240269e-04 -2.346255e-04 -2.456600e-04
## ASV3855     -2.745899e-38 -1.695082e-04 -1.773081e-04 -1.854133e-04
## ASV0810      3.612395e-38  2.257866e-04  2.363437e-04  2.472942e-04
## ASV1765      4.274591e-38  2.690489e-04  2.816640e-04  2.948134e-04
## ASV0763      2.361034e-38  1.465670e-04  1.533222e-04  1.603741e-04
## ASV0302     -2.606538e-38 -1.600310e-04 -1.673558e-04 -1.749588e-04
## ASV2643     -3.633385e-38 -2.182928e-04 -2.283087e-04 -2.384619e-04
## ASV0440      1.322707e-38  8.422834e-05  8.815537e-05  9.230920e-05
## ASV4899     -2.544501e-38 -1.536627e-04 -1.606494e-04 -1.678162e-04
## ASV0287     -1.478757e-38 -9.292120e-05 -9.725620e-05 -1.017919e-04
## ASV3220      1.836803e-38  1.161241e-04  1.216499e-04  1.273510e-04
## ASV1007     -1.121338e-38 -6.728679e-05 -7.028801e-05 -7.339891e-05
## ASV2929     -7.419660e-39 -4.311374e-05 -4.497698e-05 -4.689418e-05
## ASV1496     -2.526874e-38 -1.600943e-04 -1.675796e-04 -1.754554e-04
## ASV4975      1.115656e-38  7.003101e-05  7.330521e-05  7.671261e-05
## ASV4392     -2.125475e-39 -1.000587e-05 -1.045338e-05 -1.076795e-05
## ASV4653     -3.040027e-38 -1.908378e-04 -1.997428e-04 -2.090413e-04
## ASV0230     -1.538055e-38 -9.753220e-05 -1.021734e-04 -1.069805e-04
## ASV0840      2.197581e-38  1.377267e-04  1.441258e-04  1.508233e-04
## ASV4132     -6.325908e-39 -4.100634e-05 -4.293526e-05 -4.499975e-05
## ASV3344      2.357074e-38  1.439519e-04  1.505178e-04  1.573191e-04
## ASV12096    -3.070205e-38 -1.933406e-04 -2.025245e-04 -2.119806e-04
## ASV1550      1.126883e-38  6.518792e-05  6.805987e-05  7.094823e-05
## ASV3542     -4.516231e-38 -2.865426e-04 -3.001232e-04 -3.142356e-04
## ASV8795     -1.761531e-38 -1.110229e-04 -1.162286e-04 -1.216610e-04
## ASV2532     -7.746705e-40 -5.875546e-06 -6.179098e-06 -6.519181e-06
## ASV3087      7.689922e-39  4.620340e-05  4.831318e-05  5.045706e-05
## ASV9476     -1.761531e-38 -1.110229e-04 -1.162225e-04 -1.216543e-04
## ASV13721    -1.761531e-38 -1.110229e-04 -1.162137e-04 -1.216446e-04
## ASV3842      3.012661e-38  1.834955e-04  1.919608e-04  2.006115e-04
## ASV1663      5.419548e-38  3.303744e-04  3.454982e-04  3.610814e-04
## ASV0432      1.275744e-38  7.761027e-05  8.122731e-05  8.488460e-05
## ASV4356      5.254926e-38  3.261442e-04  3.413207e-04  3.570195e-04
## ASV4524      1.227914e-38  7.898520e-05  8.277556e-05  8.672685e-05
## ASV0169     -2.531687e-38 -1.605636e-04 -1.682030e-04 -1.761170e-04
## ASV0368     -2.177830e-38 -1.380267e-04 -1.445869e-04 -1.513839e-04
## ASV2603     -3.159731e-53  4.204211e-08  6.910920e-08  7.149094e-08
## ASV3777      2.922679e-38  1.824661e-04  1.909655e-04  1.998014e-04
## ASV3978      2.569218e-38  1.586095e-04  1.659648e-04  1.735499e-04
## ASV0413     -2.056321e-38 -1.302726e-04 -1.364414e-04 -1.428516e-04
## ASV0997      2.545339e-53 -4.203807e-08 -4.481703e-08 -4.514101e-08
## ASV1195      2.545339e-53 -4.203875e-08 -4.481233e-08 -4.514043e-08
## ASV2522     -1.383160e-38 -8.592150e-05 -8.992256e-05 -9.406205e-05
## ASV4733      2.505383e-38  1.568063e-04  1.641391e-04  1.717519e-04
## ASV1063      4.307029e-38  2.743104e-04  2.873538e-04  3.009411e-04
## ASV0612     -5.552434e-38 -3.502166e-04 -3.666972e-04 -3.838619e-04
## ASV1903     -4.307029e-38 -2.743104e-04 -2.873057e-04 -3.008885e-04
## ASV3576     -1.197723e-38 -7.951576e-05 -8.341458e-05 -8.752376e-05
## ASV4285     -3.095438e-38 -1.955813e-04 -2.048959e-04 -2.144997e-04
## ASV3406     -1.626288e-38 -1.018944e-04 -1.066345e-04 -1.115894e-04
## ASV2379     -3.192772e-38 -1.902829e-04 -1.989844e-04 -2.077427e-04
## ASV0528      3.816776e-38  2.392023e-04  2.504446e-04  2.620815e-04
## ASV6190     -4.716481e-39 -3.097497e-05 -3.242179e-05 -3.399961e-05
## ASV1537     -6.867209e-40 -2.662551e-06 -2.751168e-06 -2.792222e-06
## ASV16780    -3.435590e-38 -2.129777e-04 -2.229593e-04 -2.332043e-04
## ASV0477      8.478532e-38  5.287614e-04  5.534110e-04  5.789935e-04
## ASV1499      1.818570e-38  1.203455e-04  1.261418e-04  1.323253e-04
## ASV14736     1.488083e-38  9.183241e-05  9.611140e-05  1.005077e-04
## ASV0179     -1.208851e-38 -7.620096e-05 -7.975793e-05 -8.348480e-05
## ASV3153      2.739063e-40  6.048219e-06  6.366185e-06  6.883729e-06
## ASV0266      3.932887e-38  2.468574e-04  2.584722e-04  2.705097e-04
## ASV0761      5.930933e-38  3.661430e-04  3.832390e-04  4.007695e-04
## ASV0269     -5.082833e-39 -3.553890e-05 -3.726639e-05 -3.918982e-05
## ASV7259     -1.025253e-38 -6.873749e-05 -7.215260e-05 -7.572973e-05
## ASV2067     -1.283911e-38 -7.773780e-05 -8.132201e-05 -8.496447e-05
## ASV2985     -3.473450e-38 -2.169699e-04 -2.271261e-04 -2.376335e-04
## ASV0975     -5.235299e-38 -3.287436e-04 -3.441549e-04 -3.601812e-04
## ASV2240      3.222151e-38  1.962929e-04  2.052263e-04  2.144798e-04
## ASV2297      1.107632e-38  6.416032e-05  6.701539e-05  6.986726e-05
## ASV2657      1.373581e-38  8.274745e-05  8.641838e-05  9.026708e-05
## ASV3784      5.617299e-53  2.681556e-06  2.841049e-06  3.107771e-06
## ASV4333      6.319462e-53  2.681555e-06  2.840779e-06  3.107297e-06
## ASV5547      2.851122e-38  1.699012e-04  1.774719e-04  1.852833e-04
## ASV5813      1.148755e-38  6.884235e-05  7.199135e-05  7.517813e-05
## ASV8049      1.342177e-38  8.228931e-05  8.613203e-05  9.004503e-05
## ASV8661     -6.319462e-53 -2.681547e-06 -2.849259e-06 -3.116111e-06
## ASV9510      1.574031e-38  9.621344e-05  1.006788e-04  1.052337e-04
## ASV1401      8.339445e-39  5.054721e-05  5.288269e-05  5.525579e-05
## ASV1417     -1.757340e-38 -1.016218e-04 -1.060072e-04 -1.105069e-04
## ASV2169      5.646140e-38  3.506219e-04  3.668805e-04  3.837656e-04
## ASV5354     -5.617299e-53 -2.681521e-06 -2.859562e-06 -3.127051e-06
## ASV5379     -6.056151e-53 -2.681520e-06 -2.859261e-06 -3.126576e-06
## ASV6078     -6.319462e-53 -2.681519e-06 -2.858960e-06 -3.126101e-06
## ASV6417      3.497862e-38  2.145508e-04  2.244963e-04  2.346929e-04
## ASV8304      2.578021e-38  1.558447e-04  1.629020e-04  1.701831e-04
## ASV8766     -5.617299e-53 -2.681528e-06 -2.876631e-06 -3.145002e-06
## ASV10861     1.088676e-38  6.511431e-05  6.809094e-05  7.109751e-05
## ASV2057      5.574988e-38  3.466268e-04  3.627652e-04  3.794810e-04
## ASV4499      2.060167e-38  1.222621e-04  1.277211e-04  1.333089e-04
## ASV7415      6.084608e-39  3.840131e-05  4.018584e-05  4.206144e-05
## ASV2475     -2.377376e-38 -1.485477e-04 -1.554706e-04 -1.626740e-04
## ASV3517     -3.830651e-38 -2.426190e-04 -2.541041e-04 -2.660502e-04
## ASV1864      2.671838e-38  1.634467e-04  1.709256e-04  1.786618e-04
## ASV2756      3.040027e-38  1.883586e-04  1.971904e-04  2.062460e-04
## ASV0778      3.040027e-38  1.883586e-04  1.971754e-04  2.062300e-04
## ASV3201      6.133857e-39  4.251226e-05  4.462056e-05  4.690409e-05
## ASV3358      3.040027e-38  1.883586e-04  1.971627e-04  2.062163e-04
## ASV5681     -3.040027e-38 -1.883586e-04 -1.971478e-04 -2.062002e-04
## ASV7256      1.456183e-38  9.122436e-05  9.542678e-05  9.986754e-05
## ASV1704     -3.126444e-38 -1.927072e-04 -2.016546e-04 -2.108569e-04
## ASV4445      5.066048e-38  3.041588e-04  3.178662e-04  3.319707e-04
## ASV8649     -3.040027e-38 -1.883585e-04 -1.971172e-04 -2.061673e-04
## ASV0597      3.161529e-38  1.958003e-04  2.048849e-04  2.142866e-04
## ASV0861      4.058681e-38  2.494954e-04  2.610095e-04  2.728904e-04
## ASV2423      4.903294e-38  3.025311e-04  3.165617e-04  3.310244e-04
## ASV1548      2.491950e-38  1.481810e-04  1.547863e-04  1.615726e-04
## ASV2564      4.121197e-38  2.521173e-04  2.636382e-04  2.755653e-04
## ASV2999      6.880709e-38  4.194366e-04  4.386481e-04  4.584310e-04
## ASV4543     -2.380519e-38 -1.506816e-04 -1.577962e-04 -1.652112e-04
## ASV8452      2.390541e-38  1.441865e-04  1.507003e-04  1.574146e-04
## ASV17287    -4.316807e-39 -2.982243e-05 -3.136348e-05 -3.296875e-05
## ASV3503     -3.040027e-38 -1.927941e-04 -2.019007e-04 -2.114054e-04
## ASV4727     -4.615837e-39 -3.273881e-05 -3.442745e-05 -3.622600e-05
## ASV5995     -2.590448e-38 -1.640652e-04 -1.717925e-04 -1.798681e-04
## ASV1665     -8.303436e-39 -5.261825e-05 -5.501886e-05 -5.760279e-05
## ASV2690     -3.943560e-38 -2.458772e-04 -2.573936e-04 -2.692929e-04
## ASV2823     -3.362732e-39 -2.013372e-05 -2.099439e-05 -2.192217e-05
## ASV5241     -5.271523e-38 -3.287219e-04 -3.441766e-04 -3.600854e-04
## ASV5473     -1.473488e-38 -9.420544e-05 -9.870138e-05 -1.033873e-04
## ASV2785      6.525124e-39  4.245505e-05  4.450373e-05  4.665149e-05
## ASV6645     -2.246124e-38 -1.389753e-04 -1.455140e-04 -1.521846e-04
## ASV0562      9.603473e-39  5.658020e-05  5.906063e-05  6.161178e-05
## ASV1163      8.953873e-39  5.670655e-05  5.937215e-05  6.215939e-05
## ASV1825      1.754274e-38  1.073738e-04  1.123263e-04  1.174105e-04
## ASV3795      3.835534e-38  2.369376e-04  2.478590e-04  2.592033e-04
## ASV3869     -8.068118e-39 -5.284172e-05 -5.536171e-05 -5.805357e-05
## ASV4330      2.938276e-38  1.825280e-04  1.910090e-04  1.998000e-04
## ASV6754      1.117095e-38  6.937410e-05  7.261327e-05  7.595290e-05
## ASV4598     -1.263892e-52 -1.673084e-06 -1.792657e-06 -1.964419e-06
## ASV2100      2.317000e-38  1.405966e-04  1.469536e-04  1.535480e-04
## ASV3518      1.152372e-38  6.986669e-05  7.305609e-05  7.632675e-05
## ASV3823      4.697848e-38  2.889604e-04  3.022847e-04  3.160522e-04
## ASV7357      2.864235e-38  1.772832e-04  1.854563e-04  1.939584e-04
## ASV7403     -3.675345e-38 -2.265246e-04 -2.370863e-04 -2.479105e-04
## ASV2934     -1.795432e-39 -9.825731e-06 -1.024419e-05 -1.064685e-05
## ASV5277     -1.913656e-38 -1.178885e-04 -1.234265e-04 -1.290577e-04
## ASV0281     -5.619807e-38 -3.473925e-04 -3.635454e-04 -3.801993e-04
## ASV11181    -2.001933e-38 -1.286404e-04 -1.347825e-04 -1.412177e-04
## ASV0254     -8.439049e-39 -4.575259e-05 -4.769365e-05 -4.954325e-05
## ASV0201     -9.079864e-39 -5.970264e-05 -6.255079e-05 -6.560398e-05
## ASV3656     -2.285292e-38 -1.482619e-04 -1.553453e-04 -1.628276e-04
## ASV7994     -4.302881e-38 -2.682037e-04 -2.807384e-04 -2.937117e-04
## ASV3584     -1.530725e-38 -8.771091e-05 -9.169881e-05 -9.555708e-05
## ASV2157      4.525094e-38  2.764732e-04  2.890633e-04  3.021358e-04
## ASV2935     -5.673941e-39 -3.546228e-05 -3.713342e-05 -3.885551e-05
## ASV9024     -4.094669e-38 -2.515052e-04 -2.632121e-04 -2.751843e-04
## ASV7711      2.358290e-38  1.500354e-04  1.571505e-04  1.645713e-04
## ASV11330    -3.040027e-38 -1.903760e-04 -1.992445e-04 -2.084969e-04
## ASV1875      2.698005e-38  1.678230e-04  1.756431e-04  1.837458e-04
## ASV5861      1.969454e-38  1.254338e-04  1.313962e-04  1.376058e-04
## ASV11562     1.682179e-39  1.091079e-05  1.149189e-05  1.204504e-05
## ASV18559    -3.040027e-38 -1.903760e-04 -1.992397e-04 -2.084915e-04
## ASV4384      2.894791e-38  1.839432e-04  1.926601e-04  2.017450e-04
## ASV1302      6.249360e-38  3.774185e-04  3.944913e-04  4.121201e-04
## ASV4673     -3.963832e-38 -2.497934e-04 -2.615870e-04 -2.738128e-04
## ASV1956      7.443625e-39  4.250821e-05  4.414550e-05  4.600040e-05
## ASV3286      2.736242e-38  1.740384e-04  1.822949e-04  1.908981e-04
## ASV4866     -4.307029e-38 -2.730910e-04 -2.859896e-04 -2.994501e-04
## ASV3129     -2.128138e-38 -1.341073e-04 -1.404031e-04 -1.469693e-04
## ASV4104      4.966319e-38  3.087393e-04  3.231119e-04  3.379973e-04
## ASV8983      4.184759e-40  2.627695e-06  2.636635e-06  2.759437e-06
## ASV2201      1.971777e-38  1.185703e-04  1.239151e-04  1.294181e-04
## ASV3055      1.396143e-38  8.143057e-05  8.501051e-05  8.865840e-05
## ASV0534     -6.525738e-38 -4.027769e-04 -4.213758e-04 -4.406330e-04
## ASV1019      1.676070e-39  1.316611e-05  1.389055e-05  1.467442e-05
## ASV18482    -3.040027e-38 -1.873584e-04 -1.960428e-04 -2.049911e-04
## ASV2694      1.076664e-38  6.297351e-05  6.567858e-05  6.850343e-05
## ASV3412     -9.750170e-39 -5.785566e-05 -6.046107e-05 -6.310247e-05
## ASV4174     -3.040027e-38 -1.873584e-04 -1.960244e-04 -2.049713e-04
## ASV4281     -3.040027e-38 -1.873584e-04 -1.960097e-04 -2.049555e-04
## ASV4949      3.461644e-38  2.105806e-04  2.201724e-04  2.300809e-04
## ASV5881      1.609510e-38  9.887132e-05  1.033845e-04  1.080832e-04
## ASV6299     -1.377015e-38 -8.329750e-05 -8.706562e-05 -9.095657e-05
## ASV0676      3.515408e-38  2.153146e-04  2.251425e-04  2.353515e-04
## ASV1066     -2.409096e-38 -1.468997e-04 -1.536397e-04 -1.605681e-04
## ASV1300     -2.045763e-38 -1.255311e-04 -1.313396e-04 -1.373043e-04
## ASV6455      9.817844e-39  6.113570e-05  6.400646e-05  6.696206e-05
## ASV3455     -3.040027e-38 -1.873584e-04 -1.960054e-04 -2.049507e-04
## ASV6531     -3.040027e-38 -1.873584e-04 -1.959907e-04 -2.049349e-04
## ASV0490      6.166980e-38  3.748416e-04  3.922913e-04  4.099512e-04
## ASV2588      2.239553e-39  1.979382e-05  2.084299e-05  2.210037e-05
## ASV5364      1.922499e-38  1.180640e-04  1.234776e-04  1.290881e-04
## ASV0981     -4.146777e-38 -2.610009e-04 -2.732745e-04 -2.860322e-04
## ASV1563     -8.506239e-39 -5.358210e-05 -5.610453e-05 -5.872911e-05
## ASV0376     -3.978714e-38 -2.504242e-04 -2.622005e-04 -2.744382e-04
## ASV7308     -7.021624e-53 -1.192073e-06 -1.312174e-06 -1.440031e-06
## ASV4817      7.003246e-39  4.058565e-05  4.232463e-05  4.411955e-05
## ASV8716     -4.519475e-38 -2.667619e-04 -2.790389e-04 -2.911944e-04
## ASV1849      5.671268e-38  3.400970e-04  3.553524e-04  3.710876e-04
## ASV9423     -4.263563e-38 -2.618940e-04 -2.741271e-04 -2.866018e-04
## ASV7690      1.464947e-39  9.742676e-06  1.027286e-05  1.077780e-05
## ASV4901      2.303209e-38  1.444036e-04  1.511733e-04  1.582000e-04
## ASV1830     -6.285775e-39 -4.546274e-05 -4.777712e-05 -5.030776e-05
## ASV2316     -3.307379e-38 -1.953075e-04 -2.044091e-04 -2.133314e-04
## ASV0693      4.634568e-38  2.895710e-04  3.030600e-04  3.170948e-04
## ASV1243     -3.231771e-39 -1.625516e-05 -1.702574e-05 -1.761577e-05
## ASV3867      1.200127e-38  7.608015e-05  7.971183e-05  8.346067e-05
## ASV7932      2.631194e-38  1.641844e-04  1.718427e-04  1.797876e-04
## ASV12608     1.835579e-38  1.182940e-04  1.239700e-04  1.299011e-04
## ASV1661      2.779380e-38  1.720062e-04  1.800455e-04  1.883001e-04
## ASV3957      2.882247e-38  1.807181e-04  1.891418e-04  1.979384e-04
## ASV0830     -4.619947e-38 -2.854054e-04 -2.985874e-04 -3.122533e-04
## ASV2078      5.209910e-38  3.238818e-04  3.389656e-04  3.545904e-04
## ASV13932    -3.040027e-38 -1.908956e-04 -1.998331e-04 -2.091406e-04
## ASV5300     -3.040027e-38 -1.908956e-04 -1.998180e-04 -2.091241e-04
## ASV1014     -1.663817e-38 -1.027899e-04 -1.075432e-04 -1.124611e-04
## ASV13059    -8.628727e-39 -5.855153e-05 -6.152166e-05 -6.460745e-05
## ASV4340      6.468906e-39  3.905374e-05  4.075089e-05  4.257039e-05
## ASV5591     -5.155192e-38 -3.181510e-04 -3.330152e-04 -3.482410e-04
## ASV6040     -4.104540e-38 -2.542931e-04 -2.661674e-04 -2.783855e-04
## ASV3904     -1.654864e-38 -1.050748e-04 -1.100335e-04 -1.152175e-04
## ASV2267     -4.739763e-39 -2.972712e-05 -3.109801e-05 -3.254094e-05
## ASV0573     -3.943174e-38 -2.386682e-04 -2.494689e-04 -2.606319e-04
## ASV0851     -4.140501e-38 -2.567189e-04 -2.685510e-04 -2.808799e-04
## ASV7805      1.250375e-38  8.007852e-05  8.388224e-05  8.786956e-05
## ASV3379      5.637508e-38  3.439529e-04  3.596006e-04  3.758394e-04
## ASV0825      2.421932e-38  1.548923e-04  1.623065e-04  1.700071e-04
## ASV2461      2.925304e-38  1.798515e-04  1.881066e-04  1.966712e-04
## ASV2783      4.049980e-38  2.507395e-04  2.624341e-04  2.744731e-04
## ASV0925      4.601356e-38  2.813424e-04  2.942269e-04  3.075364e-04
## ASV7023     -4.265189e-38 -2.673558e-04 -2.799002e-04 -2.929111e-04
## ASV5319      7.620300e-39  4.853832e-05  5.083472e-05  5.323111e-05
## ASV3213      2.656255e-38  1.668734e-04  1.746892e-04  1.828243e-04
## ASV3748     -6.185416e-39 -4.119452e-05 -4.325325e-05 -4.539423e-05
## ASV5491     -9.286837e-39 -6.057396e-05 -6.352451e-05 -6.660451e-05
## ASV7931      1.679205e-38  1.051736e-04  1.100627e-04  1.151692e-04
## ASV12767    -3.040027e-38 -1.916526e-04 -2.006726e-04 -2.100598e-04
## ASV6389      3.072072e-38  1.931572e-04  2.022568e-04  2.116910e-04
## ASV14867    -3.040027e-38 -1.916526e-04 -2.006571e-04 -2.100429e-04
## ASV5105      1.745172e-38  1.114350e-04  1.167591e-04  1.222906e-04
## ASV15927    -3.040027e-38 -1.910954e-04 -2.000476e-04 -2.093741e-04
## ASV2004      1.066040e-38  6.579782e-05  6.879071e-05  7.193700e-05
## ASV5554      6.498068e-40 -2.894872e-06 -3.293912e-06 -3.800176e-06
## ASV10929    -2.126941e-38 -1.337494e-04 -1.399882e-04 -1.465187e-04
## ASV12778    -1.055950e-38 -6.603871e-05 -6.909643e-05 -7.230028e-05
## ASV14006    -3.040027e-38 -1.910954e-04 -2.000139e-04 -2.093370e-04
## ASV1603      2.961751e-38  1.867367e-04  1.955019e-04  2.046465e-04
## ASV11948     1.599421e-38  9.665367e-05  1.010360e-04  1.055455e-04
## ASV12912    -3.040027e-38 -1.917999e-04 -2.008451e-04 -2.102477e-04
## ASV13147    -3.040027e-38 -1.917999e-04 -2.008298e-04 -2.102310e-04
## ASV14761    -3.040027e-38 -1.917999e-04 -2.008145e-04 -2.102143e-04
## ASV8521      2.543542e-38  1.542258e-04  1.612770e-04  1.685027e-04
## ASV8581     -3.040027e-38 -1.917999e-04 -2.008044e-04 -2.102032e-04
## ASV9875     -4.820070e-39 -3.253078e-05 -3.414615e-05 -3.585534e-05
## ASV9986      1.996192e-38  1.270076e-04  1.330085e-04  1.392857e-04
## ASV2376      3.592571e-38  2.229117e-04  2.332582e-04  2.439825e-04
## ASV17535    -3.040027e-38 -1.917999e-04 -2.007937e-04 -2.101914e-04
## ASV14330    -3.040027e-38 -1.861571e-04 -1.946604e-04 -2.034824e-04
## ASV1333     -6.464688e-38 -3.868483e-04 -4.041529e-04 -4.220150e-04
## ASV2498      1.399899e-38  9.132833e-05  9.577494e-05  1.004046e-04
## ASV6352     -1.271937e-38 -7.623985e-05 -7.963501e-05 -8.315930e-05
## ASV8601     -1.560724e-38 -9.525907e-05 -9.957293e-05 -1.040688e-04
## ASV9776     -1.201910e-38 -7.137216e-05 -7.448998e-05 -7.774732e-05
## ASV1916      2.695835e-38  1.650723e-04  1.725745e-04  1.804001e-04
## ASV1555      3.012867e-39  2.055543e-05  2.155867e-05  2.264650e-05
## ASV2499      4.118412e-38  2.590629e-04  2.711912e-04  2.838422e-04
## ASV0703      3.417865e-38  2.136636e-04  2.235686e-04  2.339328e-04
## ASV2047      4.569240e-38  2.833889e-04  2.967019e-04  3.103434e-04
## ASV5492     -3.040027e-38 -1.923284e-04 -2.013906e-04 -2.108471e-04
## ASV6549     -2.922461e-39 -1.951263e-05 -2.045707e-05 -2.147244e-05
## ASV7757     -1.023691e-38 -6.792423e-05 -7.124975e-05 -7.475915e-05
## ASV0173      2.106487e-53 -1.430885e-06 -1.563536e-06 -1.710517e-06
## ASV1248     -9.723342e-39 -5.858917e-05 -6.122150e-05 -6.394305e-05
## ASV6502     -2.106487e-53  1.430888e-06  1.567534e-06  1.714836e-06
## ASV9844     -2.106487e-53  1.430889e-06  1.567302e-06  1.714575e-06
## ASV3903      1.930258e-38  1.224721e-04  1.282841e-04  1.343247e-04
## ASV8199     -9.128111e-53  1.430890e-06  1.559470e-06  1.706024e-06
## ASV3309     -1.497663e-39 -8.716180e-06 -9.095356e-06 -9.481619e-06
## ASV5826     -4.227710e-39 -2.809422e-05 -2.943239e-05 -3.088031e-05
## ASV1480     -4.064236e-38 -2.572699e-04 -2.694254e-04 -2.820821e-04
## ASV3090      8.921726e-39  5.486483e-05  5.739845e-05  6.001150e-05
## ASV0758     -2.629440e-38 -1.572807e-04 -1.644161e-04 -1.716826e-04
## ASV0811     -7.891690e-39 -4.750576e-05 -4.956644e-05 -5.176943e-05
## ASV2653      1.990638e-38  1.273400e-04  1.334063e-04  1.397370e-04
## ASV0978      2.050744e-38  1.315675e-04  1.379013e-04  1.444609e-04
## ASV6640     -4.293631e-38 -2.673489e-04 -2.798504e-04 -2.927682e-04
## ASV3423     -1.489408e-39 -1.190960e-05 -1.253818e-05 -1.325844e-05
## ASV0617      4.515055e-38  2.688460e-04  2.812933e-04  2.936747e-04
## ASV14947    -4.307029e-38 -2.700078e-04 -2.826789e-04 -2.958176e-04
## ASV18367    -2.279611e-38 -1.474061e-04 -1.544992e-04 -1.619066e-04
## ASV4574      3.460524e-38  2.077722e-04  2.171796e-04  2.268073e-04
## ASV10514    -2.275386e-38 -1.439615e-04 -1.507744e-04 -1.578509e-04
## ASV11779    -1.017620e-38 -7.115572e-05 -7.478736e-05 -7.863220e-05
## ASV7528     -3.681356e-38 -2.331148e-04 -2.441242e-04 -2.555861e-04
## ASV13153    -2.102070e-38 -1.340028e-04 -1.403497e-04 -1.469862e-04
## ASV7858     -1.867022e-38 -1.190095e-04 -1.246355e-04 -1.305281e-04
## ASV8722      7.224469e-39  4.121891e-05  4.303585e-05  4.483056e-05
## ASV6585     -4.299129e-38 -2.695078e-04 -2.820834e-04 -2.951905e-04
## ASV3311     -3.911596e-38 -2.360605e-04 -2.466401e-04 -2.576270e-04
## ASV2469      2.834923e-40  3.668478e-06  3.891183e-06  4.160877e-06
## ASV11340    -1.930957e-38 -1.170539e-04 -1.224138e-04 -1.279030e-04
## ASV1718      3.713120e-39  2.219162e-05  2.317936e-05  2.419817e-05
## ASV2117     -4.252638e-38 -2.673006e-04 -2.798353e-04 -2.928771e-04
## ASV8252     -3.040027e-38 -1.900898e-04 -1.989505e-04 -2.081753e-04
## ASV8533      6.014853e-39  3.735595e-05  3.910481e-05  4.090501e-05
## ASV9507      4.979750e-39  2.904895e-05  3.032677e-05  3.162541e-05
## ASV0706      2.094894e-38  1.347501e-04  1.411907e-04  1.479346e-04
## ASV10312    -3.040027e-38 -1.900898e-04 -1.989344e-04 -2.081575e-04
## ASV10696    -3.040027e-38 -1.900898e-04 -1.989194e-04 -2.081412e-04
## ASV11203    -3.040027e-38 -1.900898e-04 -1.989045e-04 -2.081248e-04
## ASV12147    -6.955153e-39 -4.533057e-05 -4.746037e-05 -4.975499e-05
## ASV4602     -1.531212e-39 -1.169241e-05 -1.227984e-05 -1.295966e-05
## ASV5568      1.386763e-39  9.790990e-06  1.034140e-05  1.087923e-05
## ASV6777      3.884789e-38  2.432217e-04  2.546186e-04  2.664409e-04
## ASV8749     -3.461286e-38 -2.144134e-04 -2.243383e-04 -2.346348e-04
## ASV4780      6.329642e-39  3.704349e-05  3.864167e-05  4.029911e-05
## ASV10116    -5.842740e-39 -3.607155e-05 -3.773513e-05 -3.946361e-05
## ASV2907      3.325350e-38  2.073596e-04  2.170021e-04  2.270277e-04
## ASV5165      4.196199e-38  2.689407e-04  2.817466e-04  2.951488e-04
## ASV6061      2.450198e-38  1.509999e-04  1.579597e-04  1.651698e-04
## ASV8082     -1.495458e-38 -9.358009e-05 -9.794880e-05 -1.024963e-04
## ASV7696     -1.520627e-38 -9.526004e-05 -9.974278e-05 -1.043790e-04
## ASV0550      3.310722e-39  1.920290e-05  2.013985e-05  2.100443e-05
## ASV7745      1.883305e-38  1.215187e-04  1.272937e-04  1.333870e-04
## ASV3607     -5.565427e-40 -2.692397e-06 -2.870538e-06 -2.964965e-06
## ASV3877     -3.040027e-38 -1.859760e-04 -1.946099e-04 -2.034280e-04
## ASV7667     -1.404587e-38 -8.486172e-05 -8.881232e-05 -9.278522e-05
## ASV9293     -1.115352e-38 -7.061379e-05 -7.405767e-05 -7.753529e-05
## ASV11653    -3.040027e-38 -1.859760e-04 -1.945843e-04 -2.034007e-04
## ASV12850     4.173417e-39  2.934525e-05  3.081898e-05  3.240380e-05
## ASV13104     6.083174e-39  3.542779e-05  3.692529e-05  3.849870e-05
## ASV14208    -3.040027e-38 -1.859760e-04 -1.945728e-04 -2.033885e-04
## ASV1552      2.661183e-38  1.703319e-04  1.784522e-04  1.869268e-04
## ASV2501      1.929824e-38  1.165097e-04  1.218363e-04  1.272768e-04
## ASV2893      3.675758e-38  2.306292e-04  2.413994e-04  2.526230e-04
## ASV3084      1.440920e-38  8.781109e-05  9.177463e-05  9.591578e-05
## ASV3599      1.944468e-38  1.180177e-04  1.234130e-04  1.289515e-04
## ASV3868     -3.040027e-38 -1.859760e-04 -1.945730e-04 -2.033891e-04
## ASV3917     -4.063152e-38 -2.502195e-04 -2.617966e-04 -2.737405e-04
## ASV5695      7.105051e-39  4.645896e-05  4.866788e-05  5.102526e-05
## ASV0131      4.806333e-39  2.534001e-05  2.643212e-05  2.742289e-05
## ASV2847      3.733878e-38  2.260448e-04  2.362493e-04  2.468228e-04
## ASV6875     -3.004690e-38 -1.855479e-04 -1.942221e-04 -2.031086e-04
## ASV1547     -6.256318e-38 -3.838487e-04 -4.015685e-04 -4.198110e-04
## ASV1501     -3.889959e-38 -2.410032e-04 -2.522380e-04 -2.638227e-04
## ASV3876      4.307029e-38  2.682652e-04  2.808253e-04  2.937909e-04
## ASV3456     -4.307029e-38 -2.682652e-04 -2.808040e-04 -2.937679e-04
## ASV1194      4.063904e-38  2.530032e-04  2.648038e-04  2.770226e-04
## ASV2135     -5.148054e-38 -3.235759e-04 -3.387600e-04 -3.545508e-04
## ASV1352      4.307029e-38  2.682652e-04  2.807453e-04  2.937041e-04
## ASV3208      4.892952e-38  3.051278e-04  3.193189e-04  3.340765e-04
## ASV1164     -8.881616e-42  2.315403e-06  2.353422e-06  2.576720e-06
## ASV3492      1.965333e-38  1.270837e-04  1.331667e-04  1.395557e-04
## ASV1601      2.373118e-38  1.476540e-04  1.545259e-04  1.616518e-04
## ASV5347     -3.102959e-38 -1.898687e-04 -1.985932e-04 -2.075920e-04
## ASV0293      2.284369e-38  1.425695e-04  1.491741e-04  1.560722e-04
## ASV1509      3.955336e-38  2.460291e-04  2.574817e-04  2.693465e-04
## ASV2801      5.911643e-39  3.596324e-05  3.754659e-05  3.923691e-05
## ASV2873     -8.888170e-39 -5.682793e-05 -5.952826e-05 -6.235588e-05
## ASV2162     -6.300125e-39 -3.856482e-05 -4.024332e-05 -4.206748e-05
## ASV0462      2.520726e-38  1.499902e-04  1.566383e-04  1.635211e-04
## ASV5367     -3.698323e-38 -2.322551e-04 -2.432479e-04 -2.545760e-04
## ASV2715      4.718652e-38  2.913497e-04  3.048250e-04  3.187649e-04
## ASV0371      5.916445e-38  3.582895e-04  3.748761e-04  3.916820e-04
## ASV8090     -4.017981e-38 -2.468750e-04 -2.583321e-04 -2.700853e-04
## ASV6320     -3.040027e-38 -1.918999e-04 -2.009150e-04 -2.103265e-04
## ASV2562      3.183314e-38  2.015163e-04  2.109771e-04  2.208834e-04
## ASV1505     -4.497269e-38 -2.829101e-04 -2.961594e-04 -3.099709e-04
## ASV4924     -3.514644e-38 -2.174022e-04 -2.275748e-04 -2.380036e-04
## ASV1437      3.899839e-38  2.427436e-04  2.541160e-04  2.658423e-04
## ASV3816     -3.289596e-39 -1.665658e-05 -1.735130e-05 -1.796610e-05
## ASV1969     -1.781194e-38 -1.166758e-04 -1.223983e-04 -1.283149e-04
## ASV3146      2.141451e-38  1.296606e-04  1.355519e-04  1.416216e-04
## ASV0321     -2.296600e-38 -1.401551e-04 -1.465833e-04 -1.532120e-04
## ASV1020      4.606201e-38  2.823986e-04  2.952382e-04  3.086392e-04
## ASV4138      2.717335e-39  1.939182e-05  2.029818e-05  2.135814e-05
## ASV0329     -2.484861e-38 -1.556872e-04 -1.629488e-04 -1.705129e-04
## ASV10647     4.261014e-39  2.781912e-05  2.915082e-05  3.056265e-05
## ASV3389      3.717957e-38  2.320106e-04  2.428685e-04  2.541028e-04
## ASV6880      2.145815e-38  1.262463e-04  1.317670e-04  1.374693e-04
## ASV2624     -4.081963e-39 -3.043467e-05 -3.208772e-05 -3.382818e-05
## ASV3686     -5.321176e-39 -4.308865e-05 -4.552102e-05 -4.813254e-05
## ASV12302    -3.040027e-38 -1.929840e-04 -2.020966e-04 -2.116192e-04
## ASV1184      3.829904e-38  2.371788e-04  2.482653e-04  2.596541e-04
## ASV3533     -1.727424e-38 -1.022634e-04 -1.069503e-04 -1.116105e-04
## ASV1735      9.671493e-39  5.709977e-05  5.958508e-05  6.216896e-05
## ASV0483     -1.721961e-38 -1.094354e-04 -1.146846e-04 -1.200913e-04
## ASV0928     -3.473252e-38 -2.180650e-04 -2.282966e-04 -2.389278e-04
## ASV12254    -3.040027e-38 -1.913047e-04 -2.002883e-04 -2.096379e-04
## ASV16025    -3.040027e-38 -1.913047e-04 -2.002731e-04 -2.096213e-04
## ASV3070     -3.040027e-38 -1.913047e-04 -2.002580e-04 -2.096047e-04
## ASV1850      6.876401e-39  4.481203e-05  4.690614e-05  4.917041e-05
## ASV8946     -3.040027e-38 -1.881795e-04 -1.969569e-04 -2.059887e-04
## ASV1536      2.557608e-38  1.578365e-04  1.651769e-04  1.727255e-04
## ASV4151      3.870283e-38  2.377255e-04  2.486534e-04  2.599624e-04
## ASV4585      5.197050e-38  3.192318e-04  3.338960e-04  3.490789e-04
## ASV4921     -1.272239e-38 -7.730103e-05 -8.086464e-05 -8.449181e-05
## ASV6172      3.040027e-38  1.881795e-04  1.969160e-04  2.059444e-04
## ASV6375     -3.040027e-38 -1.881795e-04 -1.969012e-04 -2.059284e-04
## ASV6501      3.553280e-38  2.148570e-04  2.245408e-04  2.345829e-04
## ASV17095    -3.040027e-38 -1.881795e-04 -1.968897e-04 -2.059160e-04
## ASV3679     -3.040027e-38 -1.881795e-04 -1.968750e-04 -2.058999e-04
## ASV5750      3.040027e-38  1.881795e-04  1.968603e-04  2.058839e-04
## ASV5922     -3.040027e-38 -1.881795e-04 -1.968456e-04 -2.058679e-04
## ASV7323     -3.040027e-38 -1.881795e-04 -1.968309e-04 -2.058519e-04
## ASV8515     -2.858717e-40 -2.598609e-06 -2.702473e-06 -2.861475e-06
## ASV8753     -3.040027e-38 -1.881794e-04 -1.968162e-04 -2.058357e-04
## ASV9197      2.076763e-38  1.291278e-04  1.351825e-04  1.414097e-04
## ASV1778      5.136227e-39  3.472629e-05  3.646327e-05  3.828883e-05
## ASV1241      3.956938e-38  2.430169e-04  2.541384e-04  2.656919e-04
## ASV1717      3.063194e-38  1.897597e-04  1.984548e-04  2.075613e-04
## ASV1112      3.616744e-38  2.185370e-04  2.284376e-04  2.386396e-04
## ASV3994      4.074550e-38  2.549915e-04  2.669419e-04  2.793187e-04
## ASV5511     -3.040027e-38 -1.889268e-04 -1.977285e-04 -2.068349e-04
## ASV8706      2.142665e-38  1.368746e-04  1.433957e-04  1.501938e-04
## ASV3049     -3.040027e-38 -1.889268e-04 -1.977165e-04 -2.068218e-04
## ASV4332      1.914390e-38  1.211334e-04  1.268165e-04  1.327647e-04
## ASV7411      3.529400e-38  2.148453e-04  2.245984e-04  2.347083e-04
## ASV7475     -3.040027e-38 -1.889268e-04 -1.977103e-04 -2.068152e-04
## ASV8988     -3.040027e-38 -1.889268e-04 -1.976954e-04 -2.067990e-04
## ASV0688     -6.647944e-38 -4.045767e-04 -4.230103e-04 -4.420537e-04
## ASV1946      1.854258e-38  1.096839e-04  1.145261e-04  1.195199e-04
## ASV3150      5.106883e-38  3.143990e-04  3.288784e-04  3.438665e-04
## ASV3508      2.562418e-38  1.541181e-04  1.610609e-04  1.682135e-04
## ASV3863     -3.040027e-38 -1.889268e-04 -1.976850e-04 -2.067876e-04
## ASV4544      2.482682e-38  1.491812e-04  1.558866e-04  1.628017e-04
## ASV4567      5.501723e-38  3.410066e-04  3.567654e-04  3.731471e-04
## ASV4855     -3.040027e-38 -1.889268e-04 -1.976696e-04 -2.067709e-04
## ASV4872      4.113850e-38  2.524147e-04  2.640128e-04  2.760007e-04
## ASV4881      2.854517e-38  1.810449e-04  1.895962e-04  1.985176e-04
## ASV5283      3.040027e-38  1.889268e-04  1.976576e-04  2.067577e-04
## ASV5302      3.622971e-38  2.233181e-04  2.335805e-04  2.442584e-04
## ASV5909      3.061925e-38  1.896020e-04  1.983835e-04  2.074810e-04
## ASV5933      2.277910e-38  1.414703e-04  1.480566e-04  1.548680e-04
## ASV6019      3.497173e-38  2.102741e-04  2.197388e-04  2.295013e-04
## ASV6043      1.313814e-38  8.385867e-05  8.784040e-05  9.199932e-05
## ASV6908      3.824426e-38  2.368505e-04  2.478355e-04  2.592050e-04
## ASV7245     -3.040027e-38 -1.889268e-04 -1.976657e-04 -2.067664e-04
## ASV7249     -3.040027e-38 -1.889268e-04 -1.976509e-04 -2.067503e-04
## ASV8349      1.007799e-38  6.353269e-05  6.651894e-05  6.962854e-05
## ASV7310     -3.040027e-38 -1.889268e-04 -1.976388e-04 -2.067370e-04
## ASV1893      2.391447e-38  1.466960e-04  1.533725e-04  1.603440e-04
## ASV2354      1.911282e-38  1.132842e-04  1.182654e-04  1.234373e-04
## ASV3435     -5.448955e-39 -3.181569e-05 -3.320433e-05 -3.462775e-05
## ASV0480      4.629385e-38  2.928217e-04  3.066051e-04  3.209760e-04
## ASV0955     -1.611560e-38 -1.017329e-04 -1.065078e-04 -1.114966e-04
## ASV10000     1.020886e-38  5.812879e-05  6.049974e-05  6.300982e-05
## ASV7215     -1.919022e-38 -1.218002e-04 -1.276170e-04 -1.336246e-04
## ASV10423    -4.307029e-38 -2.673359e-04 -2.798107e-04 -2.926796e-04
## ASV6008     -2.295054e-38 -1.427712e-04 -1.494599e-04 -1.563504e-04
## ASV9330     -4.307029e-38 -2.673359e-04 -2.797798e-04 -2.926461e-04
## ASV6051      4.307029e-38  2.673359e-04  2.797587e-04  2.926232e-04
## ASV1675      2.850556e-38  1.766986e-04  1.849573e-04  1.934524e-04
## ASV2043      1.796313e-38  1.143165e-04  1.196759e-04  1.253255e-04
## ASV3634      1.657424e-38  1.073097e-04  1.124428e-04  1.178483e-04
## ASV4077     -4.307029e-38 -2.673359e-04 -2.797484e-04 -2.926122e-04
## ASV4754      2.111215e-38  1.295542e-04  1.355087e-04  1.416643e-04
## ASV6095      5.041514e-38  3.074431e-04  3.214455e-04  3.359546e-04
## ASV6288      3.701042e-38  2.272036e-04  2.376571e-04  2.484550e-04
## ASV6507     -4.307029e-38 -2.673359e-04 -2.797356e-04 -2.925982e-04
## ASV8905      2.217060e-38  1.359803e-04  1.422097e-04  1.486680e-04
## ASV9728     -4.307029e-38 -2.673359e-04 -2.797182e-04 -2.925793e-04
## ASV11144    -4.307029e-38 -2.673359e-04 -2.796972e-04 -2.925565e-04
## ASV1615     -1.709114e-38 -1.074288e-04 -1.124152e-04 -1.176496e-04
## ASV2709     -5.265615e-38 -3.261790e-04 -3.412231e-04 -3.568765e-04
## ASV3003      4.124255e-38  2.582661e-04  2.703525e-04  2.829077e-04
## ASV5163     -3.973936e-38 -2.464743e-04 -2.578172e-04 -2.696584e-04
## ASV6622      2.738557e-38  1.727279e-04  1.808500e-04  1.893119e-04
## ASV1076     -4.094550e-38 -2.551633e-04 -2.669443e-04 -2.792684e-04
## ASV7895      1.010756e-38  6.074772e-05  6.343775e-05  6.624779e-05
## ASV10577    -3.040027e-38 -1.928987e-04 -2.020160e-04 -2.115314e-04
## ASV1272      3.040027e-38  1.928987e-04  2.020005e-04  2.115145e-04
## ASV2492     -1.394931e-38 -9.461253e-05 -9.932116e-05 -1.043102e-04
## ASV5195      3.716463e-38  2.321816e-04  2.429891e-04  2.542438e-04
## ASV5267      2.283564e-38  1.401888e-04  1.465987e-04  1.532559e-04
## ASV6317      3.129533e-38  1.974014e-04  2.066831e-04  2.163512e-04
## ASV2296      1.134976e-38  7.105442e-05  7.433086e-05  7.778684e-05
## ASV2290     -2.862878e-38 -1.747503e-04 -1.827382e-04 -1.909943e-04
## ASV3726      2.369877e-38  1.510246e-04  1.581759e-04  1.656546e-04
## ASV1169      2.077988e-38  1.282697e-04  1.342021e-04  1.403385e-04
## ASV0189     -1.913851e-38 -1.222784e-04 -1.280991e-04 -1.341725e-04
## ASV2729      7.315664e-38  4.635352e-04  4.852947e-04  5.080957e-04
## ASV3469      1.681316e-38  1.055506e-04  1.104588e-04  1.156005e-04
## ASV0762     -4.132117e-38 -2.523827e-04 -2.638736e-04 -2.757956e-04
## ASV9001     -3.942320e-38 -2.338743e-04 -2.447174e-04 -2.554491e-04
## ASV14604    -3.040027e-38 -1.875363e-04 -1.962898e-04 -2.052590e-04
## ASV7439      8.355129e-39  5.513076e-05  5.774817e-05  6.057457e-05
## ASV8625     -3.040027e-38 -1.875363e-04 -1.962775e-04 -2.052458e-04
## ASV11553     5.453855e-39  3.649723e-05  3.824553e-05  4.014239e-05
## ASV14440     1.807961e-39  5.557487e-06  5.529468e-06  5.497494e-06
## ASV16106    -3.040027e-38 -1.875363e-04 -1.962645e-04 -2.052319e-04
## ASV16110    -3.040027e-38 -1.875363e-04 -1.962497e-04 -2.052160e-04
## ASV2229      5.454727e-38  3.317481e-04  3.467966e-04  3.623987e-04
## ASV3854     -2.940801e-38 -1.814868e-04 -1.899200e-04 -1.986008e-04
## ASV5512     -3.040027e-38 -1.875363e-04 -1.962298e-04 -2.051947e-04
## ASV5939      4.051032e-38  2.517148e-04  2.633768e-04  2.755003e-04
## ASV6676     -2.099735e-38 -1.296288e-04 -1.356335e-04 -1.418343e-04
## ASV8381     -3.040027e-38 -1.875363e-04 -1.961968e-04 -2.051588e-04
## ASV2735      3.819536e-38  2.383531e-04  2.494871e-04  2.610226e-04
## ASV9816     -3.040027e-38 -1.875363e-04 -1.961870e-04 -2.051481e-04
## ASV1382      1.413492e-38  8.485637e-05  8.849882e-05  9.241991e-05
## ASV1408     -3.040027e-38 -1.880497e-04 -1.968391e-04 -2.058636e-04
## ASV4902      1.822626e-38  1.188619e-04  1.245469e-04  1.305726e-04
## ASV5600      2.358151e-38  1.456094e-04  1.522415e-04  1.592028e-04
## ASV0815     -6.893418e-39 -4.095596e-05 -4.273514e-05 -4.460409e-05
## ASV11867    -3.040027e-38 -1.880497e-04 -1.968314e-04 -2.058555e-04
## ASV16064    -3.040027e-38 -1.880497e-04 -1.968165e-04 -2.058395e-04
## ASV2250      3.778290e-38  2.360710e-04  2.470556e-04  2.584994e-04
## ASV2417      8.393779e-39  5.498759e-05  5.762734e-05  6.042548e-05
## ASV2807      5.078724e-38  3.078239e-04  3.218364e-04  3.362687e-04
## ASV3224     -3.040027e-38 -1.880496e-04 -1.967824e-04 -2.058026e-04
## ASV4115     -3.040027e-38 -1.880496e-04 -1.967676e-04 -2.057866e-04
## ASV4876      5.076969e-39  3.090318e-05  3.228119e-05  3.372790e-05
## ASV5291      3.000267e-38  1.833589e-04  1.917662e-04  2.004362e-04
## ASV5834      1.431891e-38  8.883356e-05  9.290578e-05  9.717113e-05
## ASV6896      3.600296e-39  2.089096e-05  2.175596e-05  2.267752e-05
## ASV7292     -3.040027e-38 -1.880496e-04 -1.967584e-04 -2.057767e-04
## ASV7924      1.717234e-38  1.079163e-04  1.129925e-04  1.182582e-04
## ASV0710      4.053541e-38  2.490368e-04  2.604155e-04  2.722530e-04
## ASV1925      3.557084e-38  2.169160e-04  2.268056e-04  2.370357e-04
## ASV4247     -3.040027e-38 -1.880496e-04 -1.967423e-04 -2.057592e-04
## ASV4549     -3.040027e-38 -1.880496e-04 -1.967276e-04 -2.057432e-04
## ASV4076      2.540680e-38  1.573982e-04  1.646470e-04  1.722062e-04
## ASV7063      2.439439e-38  1.527193e-04  1.598376e-04  1.672491e-04
## ASV1487      2.692193e-38  1.626816e-04  1.700131e-04  1.776056e-04
## ASV1405      1.037653e-38  6.696370e-05  7.020605e-05  7.356742e-05
## ASV3851      2.625913e-38  1.665276e-04  1.743868e-04  1.825837e-04
## ASV0896      8.120745e-39  5.092518e-05  5.324646e-05  5.572062e-05
## ASV5581      3.805940e-38  2.421543e-04  2.536292e-04  2.656057e-04
## ASV7053     -1.285656e-38 -7.996892e-05 -8.369233e-05 -8.755161e-05
## ASV7171     -3.040027e-38 -1.916490e-04 -2.006501e-04 -2.100354e-04
## ASV4017     -4.180093e-38 -2.625097e-04 -2.747755e-04 -2.875725e-04
## ASV5846      4.010423e-39  1.723843e-05  1.770025e-05  1.812655e-05
## ASV0203      7.819022e-40  2.034192e-06  1.951967e-06  1.917056e-06
## ASV13271     5.305006e-39  3.018169e-05  3.141730e-05  3.272029e-05
## ASV9487      2.095671e-38  1.213688e-04  1.265644e-04  1.319491e-04
## ASV2056     -4.300127e-38 -2.690723e-04 -2.816017e-04 -2.946628e-04
## ASV16933    -4.306987e-38 -2.651995e-04 -2.775325e-04 -2.901936e-04
## ASV0360      1.918749e-38  1.155774e-04  1.207641e-04  1.261452e-04
## ASV1798     -2.802420e-38 -1.725057e-04 -1.805041e-04 -1.887340e-04
## ASV17286    -3.040027e-38 -1.914653e-04 -2.004564e-04 -2.098217e-04
## ASV8175     -3.040027e-38 -1.914653e-04 -2.004412e-04 -2.098050e-04
## ASV6679      3.296473e-38  2.032509e-04  2.125905e-04  2.222934e-04
## ASV6776      1.622943e-38  9.825720e-05  1.027215e-04  1.073166e-04
## ASV9062     -3.040027e-38 -1.914653e-04 -2.004275e-04 -2.097900e-04
## ASV9564     -2.383930e-39 -1.677447e-05 -1.760784e-05 -1.852284e-05
## ASV6431     -3.040027e-38 -1.914653e-04 -2.004113e-04 -2.097721e-04
## ASV9940      1.268056e-38  7.828570e-05  8.188743e-05  8.562720e-05
## ASV7001     -4.306965e-38 -2.656047e-04 -2.779110e-04 -2.906028e-04
## ASV3044      4.866605e-38  3.000383e-04  3.138253e-04  3.281566e-04
## ASV6684      1.701217e-38  1.102322e-04  1.155467e-04  1.211028e-04
## ASV12278    -6.143921e-54  1.530461e-06  1.693128e-06  1.849665e-06
## ASV3543     -2.973498e-38 -1.782008e-04 -1.861640e-04 -1.944111e-04
## ASV6397     -6.143921e-54  1.530455e-06  1.690047e-06  1.846338e-06
## ASV9939     -6.143921e-54  1.530455e-06  1.689777e-06  1.846060e-06
## ASV9432      2.421299e-38  1.543643e-04  1.616790e-04  1.693263e-04
## ASV2630     -3.036049e-38 -1.921425e-04 -2.011898e-04 -2.106340e-04
## ASV2175      3.981968e-38  2.521290e-04  2.640616e-04  2.764709e-04
## ASV4107      3.313480e-38  2.081726e-04  2.178987e-04  2.280472e-04
## ASV9172     -3.754861e-39 -2.613361e-05 -2.751212e-05 -2.893022e-05
## ASV3141      3.886221e-38  2.473233e-04  2.590304e-04  2.712651e-04
## ASV9010     -3.040027e-38 -1.918541e-04 -2.008996e-04 -2.103073e-04
## ASV2550      3.065648e-38  1.904841e-04  1.992763e-04  2.084471e-04
## ASV5845     -3.040027e-38 -1.918541e-04 -2.008891e-04 -2.102959e-04
## ASV3998      3.040027e-38  1.918541e-04  2.008738e-04  2.102792e-04
## ASV1389     -3.519234e-38 -2.084464e-04 -2.178756e-04 -2.274081e-04
## ASV0615     -3.494985e-38 -2.170379e-04 -2.270969e-04 -2.375498e-04
## ASV9127     -4.295812e-38 -2.660239e-04 -2.784425e-04 -2.912200e-04
## ASV1190      6.227206e-38  3.791995e-04  3.964633e-04  4.143238e-04
## ASV1211      1.540939e-38  9.543088e-05  9.975473e-05  1.043344e-04
## ASV1766     -4.387851e-38 -2.733618e-04 -2.861759e-04 -2.993903e-04
## ASV2337      3.040027e-38  1.901482e-04  1.991446e-04  2.083800e-04
## ASV2463      6.547162e-39  4.089291e-05  4.288063e-05  4.486720e-05
## ASV2806      2.350639e-38  1.426239e-04  1.489910e-04  1.556859e-04
## ASV0439     -3.933876e-38 -2.450859e-04 -2.565738e-04 -2.684196e-04
## ASV0839      3.657136e-38  2.330023e-04  2.439795e-04  2.555045e-04
## ASV14975    -3.040027e-38 -1.901482e-04 -1.991175e-04 -2.083510e-04
## ASV17712    -3.040027e-38 -1.901482e-04 -1.991023e-04 -2.083347e-04
## ASV2010     -3.617871e-39 -2.172256e-05 -2.274884e-05 -2.375531e-05
## ASV2041      1.522290e-38  9.914111e-05  1.039512e-04  1.089710e-04
## ASV2124     -3.911540e-38 -2.452818e-04 -2.568207e-04 -2.687616e-04
## ASV2585      5.467705e-38  3.399271e-04  3.556852e-04  3.720660e-04
## ASV3314      4.261380e-38  2.685663e-04  2.811930e-04  2.943385e-04
## ASV5051     -4.435826e-39 -2.508472e-05 -2.619652e-05 -2.727019e-05
## ASV10784     1.549939e-38  9.565357e-05  1.000253e-04  1.045960e-04
## ASV3279     -3.040027e-38 -1.901482e-04 -1.990656e-04 -2.082950e-04
## ASV9498      2.517739e-39  1.352281e-05  1.403866e-05  1.457595e-05
## ASV1059     -3.201432e-38 -2.026505e-04 -2.121973e-04 -2.221637e-04
## ASV13008    -3.040027e-38 -1.901482e-04 -1.990501e-04 -2.082783e-04
## ASV15803    -3.040027e-38 -1.901482e-04 -1.990350e-04 -2.082619e-04
## ASV2559     -2.948843e-38 -1.845434e-04 -1.931675e-04 -2.021286e-04
## ASV2623     -3.040027e-38 -1.901482e-04 -1.990204e-04 -2.082459e-04
## ASV2802     -1.729596e-38 -1.069996e-04 -1.119754e-04 -1.171079e-04
## ASV3799      4.722875e-38  2.924438e-04  3.059715e-04  3.200077e-04
## ASV5274      2.926160e-40 -1.213347e-07 -1.623213e-07 -2.675312e-07
## ASV5835      1.840073e-38  1.170396e-04  1.225568e-04  1.283454e-04
## ASV7251     -3.040027e-38 -1.901482e-04 -1.990171e-04 -2.082422e-04
## ASV7616     -3.040027e-38 -1.901482e-04 -1.990020e-04 -2.082258e-04
## ASV9576     -3.040027e-38 -1.901482e-04 -1.989871e-04 -2.082094e-04
## ASV2870      2.222798e-38  1.393236e-04  1.458032e-04  1.525742e-04
## ASV3668     -1.934353e-38 -1.223508e-04 -1.280557e-04 -1.340585e-04
## ASV1633      1.449813e-38  9.240424e-05  9.678811e-05  1.013647e-04
## ASV6060      5.336585e-40 -2.832430e-06 -3.274915e-06 -3.734563e-06
## ASV6305      1.504178e-38  9.556114e-05  1.000784e-04  1.047954e-04
## ASV5164      1.050440e-38  6.259282e-05  6.537352e-05  6.824256e-05
## ASV7252     -3.040027e-38 -1.904667e-04 -1.993953e-04 -2.086594e-04
## ASV9343      2.549441e-38  1.637330e-04  1.715343e-04  1.797115e-04
## ASV6835     -5.243379e-39 -3.195744e-05 -3.342867e-05 -3.493621e-05
## ASV1264      3.746140e-38  2.322761e-04  2.429997e-04  2.541654e-04
## ASV0591      4.302786e-39  2.120185e-05  2.191394e-05  2.264048e-05
## ASV1351      4.271102e-38  2.678640e-04  2.803971e-04  2.934361e-04
## ASV14224    -3.040027e-38 -1.904667e-04 -1.993581e-04 -2.086189e-04
## ASV1432     -3.040027e-38 -1.904667e-04 -1.993430e-04 -2.086024e-04
## ASV1559     -2.528411e-38 -1.594524e-04 -1.669557e-04 -1.747647e-04
## ASV2182      4.778811e-38  2.962242e-04  3.099238e-04  3.241558e-04
## ASV2304     -2.708802e-39 -1.601150e-05 -1.670363e-05 -1.742935e-05
## ASV6838     -3.142838e-40 -1.672932e-06 -1.740085e-06 -1.806565e-06
## ASV1125     -4.350800e-39 -2.838401e-05 -2.976986e-05 -3.121142e-05
## ASV17948    -3.040027e-38 -1.904667e-04 -1.993376e-04 -2.085964e-04
## ASV2609      2.655132e-38  1.677912e-04  1.756864e-04  1.839219e-04
## ASV6128     -2.466133e-38 -1.560803e-04 -1.634252e-04 -1.710617e-04
## ASV1338      6.928014e-39  3.829831e-05  3.985094e-05  4.144080e-05
## ASV2136      1.168449e-38  6.962873e-05  7.270889e-05  7.590550e-05
## ASV0929     -2.820965e-38 -1.741655e-04 -1.821933e-04 -1.905272e-04
## ASV3479      1.970806e-38  1.201861e-04  1.258171e-04  1.314954e-04
## ASV0886      5.136435e-38  3.203104e-04  3.350813e-04  3.505603e-04
## ASV1652      2.340602e-38  1.468980e-04  1.537459e-04  1.609022e-04
## ASV1160      4.237225e-38  2.655264e-04  2.779175e-04  2.908296e-04
## ASV5260     -7.373515e-39 -4.969674e-05 -5.221326e-05 -5.481669e-05
## ASV2352      5.398417e-38  3.273339e-04  3.419761e-04  3.573119e-04
## ASV0986     -2.115293e-38 -1.295719e-04 -1.355023e-04 -1.416486e-04
## ASV2021      3.465695e-38  2.146963e-04  2.245627e-04  2.348670e-04
## ASV16599    -2.647078e-38 -1.746005e-04 -1.831446e-04 -1.920768e-04
## ASV3497      2.586345e-38  1.628295e-04  1.704221e-04  1.783828e-04
## ASV1305      1.673612e-38  1.091381e-04  1.143720e-04  1.198884e-04
## ASV0927     -4.266149e-38 -2.519204e-04 -2.629780e-04 -2.744173e-04
## ASV0647     -1.441760e-38 -8.332916e-05 -8.671363e-05 -9.038312e-05
## ASV1832     -1.733868e-38 -1.067927e-04 -1.116805e-04 -1.167754e-04
## ASV1277      2.048258e-38  1.271360e-04  1.329484e-04  1.390577e-04
## ASV22332    -3.040027e-38 -1.908312e-04 -1.997726e-04 -2.090723e-04
## ASV10080    -2.446061e-39 -2.302014e-05 -2.444863e-05 -2.596897e-05
## ASV14157     3.867611e-39  2.549700e-05  2.673826e-05  2.804568e-05
## ASV15829    -3.040027e-38 -1.908312e-04 -1.997570e-04 -2.090553e-04
## ASV3609     -3.040027e-38 -1.908312e-04 -1.997419e-04 -2.090388e-04
## ASV5737      7.314901e-39  4.282641e-05  4.471077e-05  4.663118e-05
## ASV1474      2.202122e-38  1.390647e-04  1.456286e-04  1.524442e-04
## ASV2028      3.244789e-38  1.915866e-04  2.000299e-04  2.087303e-04
## ASV0818      3.682930e-38  2.295910e-04  2.402419e-04  2.513380e-04
## ASV0505     -3.143796e-38 -1.984266e-04 -2.077189e-04 -2.174329e-04
## ASV1813      1.571428e-38  9.418886e-05  9.837599e-05  1.027263e-04
## ASV0512      3.207171e-38  2.057845e-04  2.154936e-04  2.257230e-04
## ASV5374     -2.330037e-38 -1.459687e-04 -1.528489e-04 -1.599570e-04
## ASV2927     -4.137624e-39 -1.947078e-05 -2.016972e-05 -2.077425e-05
## ASV3596      2.376141e-38  1.437805e-04  1.503764e-04  1.571040e-04
## ASV1137      1.438563e-38  8.598870e-05  8.987838e-05  9.383753e-05
## ASV4541      2.106487e-53  1.952358e-06  2.084692e-06  2.279736e-06
## ASV9872     -2.106487e-53 -1.952358e-06 -2.084468e-06 -2.279389e-06
## ASV0359     -1.119999e-38 -6.740368e-05 -7.046592e-05 -7.359740e-05
## ASV0720     -1.891173e-38 -1.149853e-04 -1.202130e-04 -1.256140e-04
## ASV10545    -2.106487e-53 -1.952360e-06 -2.093533e-06 -2.289060e-06
## ASV13384    -2.106487e-53 -1.952360e-06 -2.093294e-06 -2.288713e-06
## ASV1456      8.683763e-40  5.031627e-06  5.264267e-06  5.488839e-06
## ASV1751     -2.106487e-53 -1.952359e-06 -2.093304e-06 -2.288617e-06
## ASV18419    -2.106487e-53 -1.952359e-06 -2.093065e-06 -2.288270e-06
## ASV2970      2.106487e-53  1.952359e-06  2.092827e-06  2.287924e-06
## ASV4215      2.393974e-38  1.491568e-04  1.560465e-04  1.632469e-04
## ASV4742      4.532485e-39  2.515511e-05  2.623482e-05  2.729110e-05
## ASV5017      7.831685e-39  4.720189e-05  4.934989e-05  5.154769e-05
## ASV5139     -2.106487e-53 -1.952361e-06 -2.090722e-06 -2.285322e-06
## ASV9133     -2.106487e-53 -1.952361e-06 -2.090487e-06 -2.284977e-06
## ASV9447     -2.106487e-53 -1.952361e-06 -2.090254e-06 -2.284631e-06
## ASV0842     -2.413783e-38 -1.426757e-04 -1.489361e-04 -1.554283e-04
## ASV12293     1.725664e-38  1.001882e-04  1.045396e-04  1.090004e-04
## ASV1965      2.844644e-38  1.790447e-04  1.874457e-04  1.961979e-04
## ASV2005      3.328825e-38  1.972640e-04  2.060169e-04  2.150186e-04
## ASV5335      2.442849e-38  1.465528e-04  1.531782e-04  1.599636e-04
## ASV6438     -2.106487e-53 -1.952407e-06 -2.112397e-06 -2.308435e-06
## ASV7798     -2.106487e-53 -1.952406e-06 -2.112127e-06 -2.308087e-06
## ASV2691     -3.211971e-38 -2.017102e-04 -2.110857e-04 -2.209079e-04
## ASV9958      2.687628e-38  1.653211e-04  1.729277e-04  1.808031e-04
## ASV1512      9.289094e-39  5.968118e-05  6.254555e-05  6.553228e-05
## ASV1226      4.374569e-38  2.711604e-04  2.837823e-04  2.968215e-04
## ASV2130     -7.723118e-38 -4.785217e-04 -5.006904e-04 -5.236748e-04
## ASV0874     -2.421411e-38 -1.489597e-04 -1.558948e-04 -1.630141e-04
## ASV5436     -3.400927e-38 -2.127463e-04 -2.226497e-04 -2.329692e-04
## ASV0383     -3.945801e-38 -2.360391e-04 -2.465237e-04 -2.574045e-04
## ASV1882      3.860660e-38  2.307050e-04  2.410792e-04  2.517258e-04
## ASV2471     -2.097231e-38 -1.296294e-04 -1.357571e-04 -1.419774e-04
## ASV4049     -2.992334e-38 -1.844698e-04 -1.929303e-04 -2.017354e-04
## ASV3014     -1.716087e-38 -1.035414e-04 -1.082522e-04 -1.130790e-04
## ASV0316     -5.955330e-38 -3.692079e-04 -3.863331e-04 -4.040803e-04
## ASV1621     -4.188630e-38 -2.565615e-04 -2.683354e-04 -2.805039e-04
## ASV13266    -3.040027e-38 -1.880310e-04 -1.967731e-04 -2.057903e-04
## ASV1635     -3.015365e-38 -1.864703e-04 -1.951243e-04 -2.040637e-04
## ASV2042      2.212274e-38  1.370036e-04  1.433097e-04  1.498845e-04
## ASV2317     -3.625878e-38 -2.236060e-04 -2.339473e-04 -2.446332e-04
## ASV3697      2.775612e-38  1.693528e-04  1.770052e-04  1.849948e-04
## ASV6404      5.135272e-38  3.117925e-04  3.258395e-04  3.404771e-04
## ASV15616     1.598885e-39  1.252583e-05  1.318534e-05  1.392581e-05
## ASV10783    -3.040027e-38 -1.880310e-04 -1.967413e-04 -2.057561e-04
## ASV6912     -2.295194e-38 -1.411980e-04 -1.477063e-04 -1.544343e-04
## ASV1561      6.267759e-38  3.821985e-04  3.995751e-04  4.176061e-04
## ASV4404      4.212588e-38  2.600586e-04  2.720251e-04  2.844630e-04
## ASV1110      3.118002e-38  1.911420e-04  1.999124e-04  2.089835e-04
## ASV2844     -9.956794e-39 -6.424874e-05 -6.732303e-05 -7.054615e-05
## ASV5224      3.087616e-38  1.905833e-04  1.993904e-04  2.085025e-04
## ASV6300     -3.040027e-38 -1.906282e-04 -1.995356e-04 -2.088123e-04
## ASV8078     -3.040027e-38 -1.906282e-04 -1.995205e-04 -2.087959e-04
## ASV9722      7.638763e-40  1.322776e-06  1.273931e-06  1.155460e-06
## ASV6911     -3.040027e-38 -1.906282e-04 -1.995054e-04 -2.087793e-04
## ASV5474     -5.969814e-39 -3.880982e-05 -4.069483e-05 -4.265848e-05
## ASV2761     -7.256661e-38 -4.479138e-04 -4.685483e-04 -4.899670e-04
## ASV5943     -1.912214e-38 -1.236351e-04 -1.295870e-04 -1.358092e-04
## ASV0600     -6.366108e-39 -3.334988e-05 -3.469497e-05 -3.597916e-05
## ASV0608     -6.544018e-38 -4.021406e-04 -4.205838e-04 -4.397245e-04
## ASV1586      1.615427e-38  9.723264e-05  1.015491e-04  1.060698e-04
## ASV0206     -7.391413e-38 -4.478934e-04 -4.679175e-04 -4.888743e-04
## ASV4042     -3.297802e-38 -2.043479e-04 -2.137771e-04 -2.235893e-04
## ASV5304     -7.902358e-40 -5.910096e-06 -6.262520e-06 -6.599728e-06
## ASV0949     -9.954426e-39 -6.976028e-05 -7.336635e-05 -7.714917e-05
## ASV1856      3.790633e-38  2.353501e-04  2.461986e-04  2.575195e-04
## ASV2584      4.811356e-39  2.807272e-05  2.929520e-05  3.054228e-05
## ASV2287     -6.997076e-40 -1.106480e-05 -1.153362e-05 -1.238952e-05
## ASV2364     -5.420195e-38 -3.341246e-04 -3.495929e-04 -3.655579e-04
## ASV11481    -4.194247e-38 -2.653106e-04 -2.778538e-04 -2.908919e-04
## ASV2906     -1.450658e-38 -9.231112e-05 -9.662339e-05 -1.011809e-04
## ASV0161     -1.798367e-38 -1.108666e-04 -1.159217e-04 -1.212094e-04
## ASV0062     -1.180453e-37 -7.282112e-04 -7.617574e-04 -7.965580e-04
## ASV3811     -2.980117e-38 -1.730739e-04 -1.810806e-04 -1.888326e-04
## ASV0225      5.662909e-39  2.937864e-05  3.066917e-05  3.179734e-05
## ASV4672     -3.832617e-38 -2.336203e-04 -2.444883e-04 -2.555206e-04
## ASV1607     -2.685569e-39 -1.764699e-05 -1.850688e-05 -1.939515e-05
## ASV3060      7.063015e-39  4.582185e-05  4.802157e-05  5.033403e-05
## ASV2275     -5.375482e-39 -3.331198e-05 -3.484389e-05 -3.644276e-05
## ASV5375      2.043085e-38  1.299111e-04  1.360118e-04  1.424283e-04
## ASV0352     -6.192788e-38 -3.888798e-04 -4.071128e-04 -4.260695e-04
## ASV1107      1.733099e-38  1.118667e-04  1.170582e-04  1.226487e-04
## ASV4887      1.718053e-38  1.020024e-04  1.065120e-04  1.111718e-04
## ASV2397     -9.028261e-39 -5.176336e-05 -5.392783e-05 -5.618596e-05
## ASV7541     -1.993270e-38 -1.223339e-04 -1.280235e-04 -1.338388e-04
## ASV7387     -4.302709e-38 -2.672686e-04 -2.796719e-04 -2.925400e-04
## ASV1355      3.917059e-38  2.448450e-04  2.562816e-04  2.681627e-04
## ASV1764     -2.085633e-38 -1.280635e-04 -1.339308e-04 -1.400211e-04
## ASV1960     -4.042510e-38 -2.368067e-04 -2.476214e-04 -2.583191e-04
## ASV0484     -7.299950e-39 -4.521144e-05 -4.728820e-05 -4.945939e-05
## ASV2487      1.291002e-38  7.405702e-05  7.712177e-05  8.035695e-05
## ASV0422      3.880713e-38  2.298089e-04  2.403809e-04  2.508994e-04
## ASV0081     -2.232702e-38 -1.425361e-04 -1.492975e-04 -1.563713e-04
## ASV1341     -2.079569e-38 -1.241630e-04 -1.296945e-04 -1.354084e-04
## ASV1001     -4.892692e-38 -2.937031e-04 -3.067659e-04 -3.203586e-04
## ASV0317     -1.068471e-38 -7.039165e-05 -7.359957e-05 -7.717667e-05
## ASV2728     -3.277736e-38 -2.028971e-04 -2.123466e-04 -2.220885e-04
## ASV0884     -4.023153e-38 -2.591340e-04 -2.713716e-04 -2.843340e-04
## ASV0464      7.463143e-39  5.458217e-05  5.746750e-05  6.053813e-05
## ASV2963      2.928852e-38  1.782162e-04  1.862593e-04  1.946485e-04
## ASV4608      1.297067e-38  8.030720e-05  8.400718e-05  8.785700e-05
## ASV3534      3.394669e-38  2.006534e-04  2.094651e-04  2.185853e-04
## ASV0291     -2.814970e-38 -1.719970e-04 -1.798012e-04 -1.879255e-04
## ASV0635     -3.916218e-38 -2.470218e-04 -2.585954e-04 -2.706939e-04
## ASV0867      3.102547e-38  1.984717e-04  2.079015e-04  2.177720e-04
## ASV1206     -4.078787e-39 -2.339819e-05 -2.439738e-05 -2.541795e-05
## ASV1230      1.272669e-53 -1.265535e-06 -1.378581e-06 -1.509575e-06
## ASV1265      8.577871e-39  5.305895e-05  5.550061e-05  5.804528e-05
## ASV1291     -2.585478e-38 -1.633595e-04 -1.710165e-04 -1.790292e-04
## ASV1524      5.610366e-38  3.390966e-04  3.543108e-04  3.701364e-04
## ASV2153     -4.330589e-38 -2.616073e-04 -2.733591e-04 -2.855715e-04
## ASV2714     -1.272669e-53  1.265481e-06  1.356915e-06  1.485953e-06
## ASV4246      1.272669e-53 -1.265481e-06 -1.356760e-06 -1.485724e-06
## ASV0945      2.803351e-38  1.736239e-04  1.816268e-04  1.899554e-04
## ASV2380      6.686867e-38  4.045924e-04  4.227792e-04  4.416956e-04
## ASV0214     -1.148976e-38 -6.178379e-05 -6.418947e-05 -6.666249e-05
## ASV10461     1.228784e-53 -1.265492e-06 -1.380158e-06 -1.511222e-06
## ASV4177      2.024045e-38  1.188520e-04  1.240255e-04  1.293827e-04
## ASV0237     -4.635378e-38 -2.914533e-04 -3.050765e-04 -3.192965e-04
## ASV11323    -5.277895e-38 -3.295087e-04 -3.447907e-04 -3.607485e-04
## ASV2232     -9.531958e-39 -5.722932e-05 -5.976065e-05 -6.240775e-05
## ASV0115     -1.712936e-38 -1.062857e-04 -1.112065e-04 -1.163135e-04
## ASV1171      8.978561e-39  5.014013e-05  5.220358e-05  5.432044e-05
## ASV1942      3.654010e-38  2.282310e-04  2.388342e-04  2.498954e-04
## ASV1889      3.873430e-39  2.303459e-05  2.404969e-05  2.510148e-05
## ASV0920      7.755445e-39  5.042277e-05  5.283401e-05  5.538044e-05
## ASV1805     -4.737769e-38 -2.929627e-04 -3.064761e-04 -3.205148e-04
## ASV1712      2.881460e-38  1.758411e-04  1.838435e-04  1.921369e-04
## ASV1458      4.287325e-38  2.583661e-04  2.703470e-04  2.824047e-04
## ASV1985      4.462910e-38  2.742112e-04  2.867868e-04  2.998383e-04
## ASV2960     -3.040027e-38 -1.761494e-04 -1.842262e-04 -1.920921e-04
## ASV5207     -1.049172e-38 -5.427013e-05 -5.670508e-05 -5.879026e-05
## ASV8548     -3.040027e-38 -1.761493e-04 -1.842092e-04 -1.920751e-04
## ASV0449     -1.610441e-38 -1.045381e-04 -1.093509e-04 -1.145895e-04
## ASV0609     -3.870970e-38 -2.373693e-04 -2.480153e-04 -2.592600e-04
## ASV1038      1.579448e-38  9.187298e-05  9.578931e-05  9.987895e-05
## ASV1145     -9.789054e-39 -5.548431e-05 -5.790054e-05 -6.029985e-05
## ASV15767    -3.040027e-38 -1.761492e-04 -1.842048e-04 -1.920716e-04
## ASV1630      4.151871e-38  2.476836e-04  2.590746e-04  2.705073e-04
## ASV1911      4.951350e-38  3.076403e-04  3.218676e-04  3.366861e-04
## ASV1950      3.783749e-38  2.235603e-04  2.338146e-04  2.440262e-04
## ASV2583      3.040027e-38  1.761490e-04  1.841585e-04  1.920234e-04
## ASV2853     -4.291496e-38 -2.575926e-04 -2.693955e-04 -2.813587e-04
## ASV2948      3.040027e-38  1.761488e-04  1.841310e-04  1.919947e-04
## ASV3116     -4.736171e-38 -2.812277e-04 -2.939794e-04 -3.068783e-04
## ASV3160     -2.650559e-38 -1.517231e-04 -1.585359e-04 -1.652089e-04
## ASV3354      2.960353e-38  1.849327e-04  1.934508e-04  2.023940e-04
## ASV3368      3.040027e-38  1.761486e-04  1.840927e-04  1.919549e-04
## ASV3464     -3.040027e-38 -1.761485e-04 -1.840793e-04 -1.919411e-04
## ASV3577      3.040027e-38  1.761484e-04  1.840660e-04  1.919273e-04
## ASV3746      3.890034e-38  2.300827e-04  2.404311e-04  2.509283e-04
## ASV3942      1.097022e-38  7.473062e-05  7.840444e-05  8.234226e-05
## ASV4000      3.040027e-38  1.761483e-04  1.840441e-04  1.919043e-04
## ASV4207      4.936724e-38  3.119637e-04  3.266051e-04  3.419091e-04
## ASV4261      3.040027e-38  1.761482e-04  1.840325e-04  1.918923e-04
## ASV4466      8.465270e-39  6.272218e-05  6.585510e-05  6.937332e-05
## ASV4487     -3.040027e-38 -1.761481e-04 -1.840230e-04 -1.918829e-04
## ASV4572     -2.258842e-38 -1.329785e-04 -1.390615e-04 -1.451164e-04
## ASV4718      3.040027e-38  1.761479e-04  1.840011e-04  1.918600e-04
## ASV4757     -3.040027e-38 -1.761478e-04 -1.839879e-04 -1.918462e-04
## ASV4929     -3.040027e-38 -1.761477e-04 -1.839748e-04 -1.918323e-04
## ASV5611     -3.040027e-38 -1.761477e-04 -1.839616e-04 -1.918185e-04
## ASV5614     -3.040027e-38 -1.761476e-04 -1.839485e-04 -1.918047e-04
## ASV5898      2.504378e-38  1.519191e-04  1.587267e-04  1.658419e-04
## ASV7627     -7.966931e-39 -3.923632e-05 -4.076888e-05 -4.215458e-05
## ASV3105     -1.724925e-38 -9.717364e-05 -1.014166e-04 -1.056119e-04
## ASV4762     -4.289539e-38 -2.577678e-04 -2.694261e-04 -2.814054e-04
## ASV5622      3.040027e-38  1.761473e-04  1.839151e-04  1.917695e-04
## ASV7129      3.728348e-38  2.277817e-04  2.381587e-04  2.489299e-04
## ASV12138    -3.040027e-38 -1.761472e-04 -1.838974e-04 -1.917507e-04
## ASV1687     -4.283297e-38 -2.610681e-04 -2.730121e-04 -2.853508e-04
## ASV2187      2.278210e-38  1.308611e-04  1.365908e-04  1.423675e-04
## ASV2204      4.347622e-38  2.646242e-04  2.765431e-04  2.889873e-04
## ASV2914      3.508626e-38  2.057955e-04  2.149060e-04  2.242116e-04
## ASV3297     -3.040027e-38 -1.761469e-04 -1.838504e-04 -1.917005e-04
## ASV3310     -3.816497e-38 -2.256207e-04 -2.356465e-04 -2.459396e-04
## ASV3677      2.298936e-40  1.184277e-05  1.277787e-05  1.386708e-05
## ASV4508      3.040027e-38  1.761467e-04  1.838226e-04  1.916708e-04
## ASV6236     -1.593537e-38 -8.649407e-05 -9.001954e-05 -9.356065e-05
## ASV6285      3.040027e-38  1.761466e-04  1.838043e-04  1.916513e-04
## ASV7576     -3.040027e-38 -1.761465e-04 -1.837914e-04 -1.916375e-04
## ASV7917     -3.040027e-38 -1.761464e-04 -1.837786e-04 -1.916237e-04
## ASV9353     -3.040027e-38 -1.761463e-04 -1.837658e-04 -1.916099e-04
## ASV1656      4.798970e-38  2.903588e-04  3.033586e-04  3.169308e-04
## ASV0280     -4.339101e-38 -2.741662e-04 -2.870461e-04 -3.005009e-04
## ASV4747     -1.331073e-41  4.189617e-06  4.482768e-06  4.913869e-06
## ASV2108     -5.359446e-38 -3.364519e-04 -3.522661e-04 -3.686721e-04
## ASV0885      1.812532e-38  1.130426e-04  1.182124e-04  1.236755e-04
## ASV2538     -1.526049e-38 -9.221747e-05 -9.633473e-05 -1.006341e-04
## ASV0968      3.382676e-38  2.083374e-04  2.180551e-04  2.280026e-04
## ASV1229     -3.040027e-38 -1.872186e-04 -1.959140e-04 -2.048459e-04
## ASV13306    -3.040027e-38 -1.872186e-04 -1.958993e-04 -2.048301e-04
## ASV13952     1.945637e-38  1.152503e-04  1.202598e-04  1.255096e-04
## ASV14631     1.562039e-38  1.030440e-04  1.080275e-04  1.133178e-04
## ASV2119      3.764688e-38  2.228659e-04  2.326490e-04  2.427975e-04
## ASV2450      3.124035e-38  1.948286e-04  2.038036e-04  2.132239e-04
## ASV2656     -3.040027e-38 -1.872186e-04 -1.958932e-04 -2.048238e-04
## ASV2942     -2.301131e-39 -1.362149e-05 -1.427558e-05 -1.489746e-05
## ASV3302      2.742672e-38  1.672455e-04  1.749264e-04  1.828162e-04
## ASV6515      1.137735e-38  6.524617e-05  6.796388e-05  7.081758e-05
## ASV6674     -3.040027e-38 -1.872186e-04 -1.958811e-04 -2.048109e-04
## ASV7296     -1.094069e-38 -6.908647e-05 -7.237505e-05 -7.576178e-05
## ASV7903      1.738022e-38  1.034712e-04  1.079785e-04  1.127219e-04
## ASV7943     -3.040027e-38 -1.872186e-04 -1.958658e-04 -2.047944e-04
## ASV8864      2.437797e-38  1.395754e-04  1.454110e-04  1.515022e-04
## ASV9389      4.228958e-39  1.879284e-05  1.923089e-05  1.973785e-05
## ASV9869     -3.040027e-38 -1.872186e-04 -1.958557e-04 -2.047835e-04
## ASV1051      3.040027e-38  1.872186e-04  1.958411e-04  2.047677e-04
## ASV13035    -1.540383e-39 -8.386023e-06 -8.760015e-06 -9.102940e-06
## ASV15744    -1.090322e-40  4.294672e-06  4.691443e-06  5.169661e-06
## ASV2526      3.821323e-39  2.032603e-05  2.106486e-05  2.186400e-05
## ASV1156      1.611748e-38  9.823857e-05  1.026215e-04  1.072468e-04
## ASV13562    -3.040027e-38 -1.872186e-04 -1.958325e-04 -2.047587e-04
## ASV1438      2.593136e-38  1.632678e-04  1.708854e-04  1.788696e-04
## ASV2268     -3.040027e-38 -1.872186e-04 -1.958249e-04 -2.047505e-04
## ASV2797      1.390718e-38  8.938751e-05  9.363221e-05  9.809971e-05
## ASV3744      3.326655e-38  2.082468e-04  2.179017e-04  2.280049e-04
## ASV8076     -3.270340e-38 -2.016943e-04 -2.109717e-04 -2.206024e-04
## ASV7055      1.304288e-38  8.573386e-05  8.992546e-05  9.431274e-05
## ASV7493     -2.756429e-38 -1.707622e-04 -1.787036e-04 -1.869047e-04
## ASV1201      6.774573e-38  4.161725e-04  4.352727e-04  4.550694e-04
## ASV5736     -5.758250e-38 -3.593149e-04 -3.759769e-04 -3.933602e-04
## ASV0558      2.739951e-38  1.734823e-04  1.816549e-04  1.901780e-04
## ASV14399    -4.069046e-38 -2.496102e-04 -2.610126e-04 -2.728660e-04
## ASV2992     -2.339360e-39 -1.416567e-05 -1.478682e-05 -1.544723e-05
## ASV4303     -2.976416e-38 -1.832659e-04 -1.916738e-04 -2.004078e-04
## ASV0565     -3.365717e-38 -2.084965e-04 -2.181042e-04 -2.281200e-04
## ASV0977     -5.261467e-38 -3.126451e-04 -3.263970e-04 -3.407237e-04
## ASV0140      2.546252e-38  1.565631e-04  1.638569e-04  1.713191e-04
## ASV14421    -3.040027e-38 -1.877511e-04 -1.964971e-04 -2.054878e-04
## ASV16909    -6.451075e-39 -4.148159e-05 -4.353518e-05 -4.561340e-05
## ASV3762     -3.040027e-38 -1.877511e-04 -1.964795e-04 -2.054689e-04
## ASV7141     -3.040027e-38 -1.877511e-04 -1.964647e-04 -2.054530e-04
## ASV3291      4.748886e-38  2.977925e-04  3.117067e-04  3.261996e-04
## ASV10440    -3.040027e-38 -1.877511e-04 -1.964477e-04 -2.054345e-04
## ASV10802     9.417493e-39  5.746902e-05  6.003369e-05  6.274165e-05
## ASV1698      4.746417e-39  3.112965e-05  3.258691e-05  3.417182e-05
## ASV2121      3.040027e-38  1.877511e-04  1.964367e-04  2.054227e-04
## ASV3549     -4.279005e-38 -2.650881e-04 -2.773144e-04 -2.900373e-04
## ASV6379      3.677931e-38  2.225829e-04  2.325748e-04  2.429796e-04
## ASV6824     -3.040027e-38 -1.877511e-04 -1.964044e-04 -2.053875e-04
## ASV8254      2.877942e-39  1.930414e-05  2.024266e-05  2.124766e-05
## ASV9951      1.288762e-38  8.227718e-05  8.614090e-05  9.021974e-05
## ASV1515     -1.325853e-38 -7.904900e-05 -8.256602e-05 -8.619237e-05
## ASV4327      9.254372e-39  5.731058e-05  5.990621e-05  6.265412e-05
## ASV0341     -1.357087e-38 -8.671636e-05 -9.082761e-05 -9.513186e-05
## ASV5562     -2.412252e-38 -1.527544e-04 -1.599334e-04 -1.674482e-04
## ASV1412      6.767584e-38  4.201901e-04  4.396075e-04  4.598366e-04
## ASV0154     -5.391687e-38 -3.376522e-04 -3.533809e-04 -3.697903e-04
## ASV3163     -2.556213e-38 -1.567666e-04 -1.639344e-04 -1.713815e-04
## ASV1782     -4.025381e-38 -2.494899e-04 -2.609656e-04 -2.729380e-04
## ASV3993     -4.863140e-39 -2.741528e-05 -2.860255e-05 -2.977603e-05
## ASV3164      1.996896e-38  1.205963e-04  1.259348e-04  1.315465e-04
## ASV1024      2.056696e-39  1.485545e-05  1.568888e-05  1.652481e-05
## ASV0771     -5.626077e-38 -3.421347e-04 -3.575670e-04 -3.736414e-04
## ASV2223     -2.335779e-38 -1.501806e-04 -1.573477e-04 -1.648403e-04
## ASV1638      9.199732e-38  5.650340e-04  5.908374e-04  6.176987e-04
## ASV0232     -2.690318e-38 -1.657767e-04 -1.733601e-04 -1.812697e-04
## ASV6771     -2.883570e-38 -1.826630e-04 -1.913977e-04 -2.003840e-04
## ASV4243     -1.246675e-38 -7.278107e-05 -7.594039e-05 -7.921868e-05
## ASV0162     -5.455773e-38 -3.381678e-04 -3.537863e-04 -3.700166e-04
## ASV0049      3.725044e-39  2.330448e-05  2.440880e-05  2.554330e-05
## ASV4697     -3.040027e-38 -1.885197e-04 -1.972508e-04 -2.063126e-04
## ASV12326     1.025350e-38  6.056248e-05  6.322546e-05  6.597473e-05
## ASV12586    -3.040027e-38 -1.885197e-04 -1.972384e-04 -2.062991e-04
## ASV1879      2.400915e-38  1.492064e-04  1.561267e-04  1.633125e-04
## ASV2864      6.571510e-38  4.109978e-04  4.301091e-04  4.500490e-04
## ASV3111     -1.774514e-38 -1.096790e-04 -1.147406e-04 -1.199933e-04
## ASV5633     -1.712650e-38 -1.053262e-04 -1.101555e-04 -1.151703e-04
## ASV5864      1.157740e-38  6.489453e-05  6.759282e-05  7.034763e-05
## ASV6364      1.407538e-38  9.021596e-05  9.451297e-05  9.900945e-05
## ASV1598      1.872054e-38  1.163842e-04  1.217341e-04  1.273486e-04
## ASV2649     -1.043700e-38 -6.870681e-05 -7.206754e-05 -7.558495e-05
## ASV4664      2.562370e-38  1.557171e-04  1.627113e-04  1.700259e-04
## ASV2654      4.234179e-38  2.616071e-04  2.736195e-04  2.861354e-04
## ASV6636     -2.018176e-39 -1.743894e-05 -1.849033e-05 -1.958542e-05
## ASV3334      3.044128e-38  1.941038e-04  2.032174e-04  2.128255e-04
## ASV0046     -5.457316e-38 -3.460956e-04 -3.623844e-04 -3.794294e-04
## ASV0661      5.768901e-38  3.522135e-04  3.682115e-04  3.848477e-04
## ASV0774      2.536083e-38  1.577446e-04  1.649943e-04  1.725925e-04
## ASV3815      3.076857e-38  1.888117e-04  1.974224e-04  2.063859e-04
## ASV0575      3.177497e-38  1.908170e-04  1.993432e-04  2.081907e-04
## ASV1953     -4.234295e-38 -2.624900e-04 -2.746136e-04 -2.872187e-04
## ASV0610      1.317110e-38  7.929158e-05  8.299858e-05  8.669662e-05
## ASV0245     -1.536988e-38 -9.581752e-05 -1.002526e-04 -1.048840e-04
## ASV3805     -2.469840e-38 -1.404729e-04 -1.464188e-04 -1.525294e-04
## ASV1182      6.198618e-38  3.909835e-04  4.092039e-04  4.283459e-04
## ASV1941     -1.053244e-53  7.998062e-07  8.789480e-07  9.631801e-07
## ASV0080     -7.465377e-38 -4.612773e-04 -4.823802e-04 -5.044451e-04
## ASV1033      2.218680e-38  1.376599e-04  1.440093e-04  1.506284e-04
## ASV5330     -2.696718e-38 -1.654887e-04 -1.732846e-04 -1.811585e-04
## ASV9702     -4.296794e-38 -2.547269e-04 -2.661158e-04 -2.777721e-04
## ASV0358      1.539547e-39  7.152983e-06  7.363360e-06  7.576182e-06
## ASV2225      2.129628e-38  1.310271e-04  1.369992e-04  1.432359e-04
## ASV2606      1.370983e-39  6.313574e-06  6.506393e-06  6.688820e-06
## ASV3510     -3.287515e-38 -2.038272e-04 -2.132088e-04 -2.229995e-04
## ASV3069      1.218600e-38  7.053803e-05  7.355026e-05  7.668391e-05
## ASV3849      2.098387e-38  1.270692e-04  1.327740e-04  1.387127e-04
## ASV1810     -5.357440e-38 -3.204176e-04 -3.346484e-04 -3.494437e-04
## ASV2046      7.494635e-38  4.674087e-04  4.891181e-04  5.117212e-04
## ASV2451     -8.175374e-39 -5.584003e-05 -5.872834e-05 -6.168666e-05
## ASV4047      3.969876e-38  2.446556e-04  2.558134e-04  2.674875e-04
## ASV7402     -3.040027e-38 -1.923314e-04 -2.014830e-04 -2.109300e-04
## ASV8250      3.759591e-38  2.364646e-04  2.474832e-04  2.590239e-04
## ASV3468      3.307445e-38  2.037500e-04  2.130516e-04  2.227689e-04
## ASV3521      6.727842e-38  4.183210e-04  4.376467e-04  4.578104e-04
## ASV6363     -2.217174e-38 -1.414624e-04 -1.482576e-04 -1.552681e-04
## ASV6444      1.488326e-38  9.475712e-05  9.916270e-05  1.038529e-04
## ASV8231      1.808446e-38  1.102774e-04  1.152593e-04  1.204614e-04
## ASV0196     -1.017205e-37 -6.276319e-04 -6.564359e-04 -6.864291e-04
## ASV12801    -3.040027e-38 -1.923315e-04 -2.014903e-04 -2.109384e-04
## ASV12906    -3.040027e-38 -1.923315e-04 -2.014748e-04 -2.109217e-04
## ASV13040    -3.040027e-38 -1.923315e-04 -2.014593e-04 -2.109049e-04
## ASV1313     -2.374210e-39 -1.893803e-05 -2.002594e-05 -2.116128e-05
## ASV14008     8.226650e-39  5.402413e-05  5.660252e-05  5.937026e-05
## ASV1546      1.291952e-38  7.521898e-05  7.844996e-05  8.180452e-05
## ASV1637      5.856290e-38  3.624426e-04  3.791887e-04  3.965670e-04
## ASV17076     2.607171e-38  1.579720e-04  1.650558e-04  1.724456e-04
## ASV2061      8.845169e-38  5.405643e-04  5.651101e-04  5.906629e-04
## ASV2177      3.483571e-38  2.218697e-04  2.323633e-04  2.433425e-04
## ASV2943      5.337967e-38  3.286892e-04  3.437916e-04  3.594599e-04
## ASV3020      4.738565e-38  2.900538e-04  3.032469e-04  3.169797e-04
## ASV30254     3.196384e-39  1.500926e-05  1.541767e-05  1.588383e-05
## ASV3219      6.639039e-38  4.069113e-04  4.254257e-04  4.447222e-04
## ASV3352      5.688884e-38  3.545029e-04  3.709025e-04  3.880320e-04
## ASV3355      2.395848e-38  1.516701e-04  1.588735e-04  1.663248e-04
## ASV3377      4.426499e-38  2.754518e-04  2.881684e-04  3.014596e-04
## ASV3449      2.679313e-38  1.612507e-04  1.684320e-04  1.759183e-04
## ASV3893      3.040027e-38  1.923315e-04  2.014427e-04  2.108872e-04
## ASV4326      1.920208e-38  1.140547e-04  1.190362e-04  1.242475e-04
## ASV5016     -3.040027e-38 -1.923315e-04 -2.014319e-04 -2.108754e-04
## ASV5152      2.590729e-38  1.516365e-04  1.581860e-04  1.649935e-04
## ASV5666     -6.417701e-40 -6.917332e-06 -7.422931e-06 -7.910079e-06
## ASV5802     -3.120044e-38 -1.971133e-04 -2.064103e-04 -2.160731e-04
## ASV6070      2.293484e-38  1.379368e-04  1.441068e-04  1.505075e-04
## ASV6488      1.946783e-38  1.194304e-04  1.248421e-04  1.305094e-04
## ASV6562     -3.040027e-38 -1.923315e-04 -2.014066e-04 -2.108480e-04
## ASV6930      2.350916e-38  1.415457e-04  1.478770e-04  1.544528e-04
## ASV7243      4.189974e-38  2.557308e-04  2.673270e-04  2.793958e-04
## ASV7506      2.687935e-38  1.627575e-04  1.700722e-04  1.776825e-04
## ASV7553     -3.040027e-38 -1.923315e-04 -2.013953e-04 -2.108356e-04
## ASV8064      1.822989e-38  1.105705e-04  1.155371e-04  1.207138e-04
## ASV8434     -1.653849e-38 -1.066008e-04 -1.117210e-04 -1.170547e-04
## ASV8858     -3.040027e-38 -1.923315e-04 -2.013767e-04 -2.108153e-04
## ASV2600      1.748986e-38  1.106879e-04  1.158927e-04  1.213239e-04
## ASV3398      6.696859e-38  4.174286e-04  4.367484e-04  4.569247e-04
## ASV4584     -3.040027e-38 -1.923315e-04 -2.013543e-04 -2.107908e-04
## ASV4864      3.422318e-38  2.115136e-04  2.211929e-04  2.313162e-04
## ASV0082     -1.333591e-37 -8.256505e-04 -8.636055e-04 -9.032077e-04
## ASV9626      2.739491e-38  1.705128e-04  1.782886e-04  1.865042e-04
## ASV1617      1.316185e-38  7.551635e-05  7.867092e-05  8.197510e-05
## ASV2765     -6.442546e-39 -4.344956e-05 -4.569756e-05 -4.797373e-05
## ASV2167     -4.147505e-38 -2.565041e-04 -2.682531e-04 -2.805376e-04
## ASV1628      2.796254e-38  1.638933e-04  1.709436e-04  1.783190e-04
## ASV3260     -6.997128e-39 -4.095827e-05 -4.278322e-05 -4.462361e-05
## ASV3645      3.141325e-39  2.338159e-05  2.451529e-05  2.582178e-05
## ASV6057     -3.956546e-38 -2.447262e-04 -2.559713e-04 -2.676972e-04
## ASV0662     -5.668642e-39 -3.298996e-05 -3.440614e-05 -3.587682e-05
## ASV4267     -4.740777e-39 -3.099248e-05 -3.254683e-05 -3.412001e-05
## ASV1070      4.123518e-38  2.606247e-04  2.728527e-04  2.856466e-04
## ASV0633     -1.133285e-38 -6.802064e-05 -7.106292e-05 -7.421256e-05
## ASV0333      4.292369e-38  2.679762e-04  2.803921e-04  2.933700e-04
## ASV0966      3.269203e-38  2.038554e-04  2.132246e-04  2.230696e-04
## ASV1848      4.620204e-38  2.930367e-04  3.068254e-04  3.212621e-04
## ASV13390    -3.040027e-38 -1.874130e-04 -1.960749e-04 -2.050258e-04
## ASV14901    -3.040027e-38 -1.874130e-04 -1.960602e-04 -2.050099e-04
## ASV1676     -3.575227e-38 -2.162113e-04 -2.259085e-04 -2.360020e-04
## ASV1756     -3.698453e-39 -2.263726e-05 -2.368596e-05 -2.475745e-05
## ASV22537    -4.467302e-39 -2.610804e-05 -2.729454e-05 -2.846886e-05
## ASV3303     -2.381323e-40 -2.829267e-06 -3.082484e-06 -3.291225e-06
## ASV4030     -1.291460e-38 -7.842669e-05 -8.201992e-05 -8.570299e-05
## ASV4871      2.388270e-38  1.495826e-04  1.564909e-04  1.637565e-04
## ASV5536      1.504228e-39  9.314311e-06  9.691860e-06  1.013705e-05
## ASV5700      1.081935e-38  6.711240e-05  7.014893e-05  7.336706e-05
## ASV8957      2.173704e-38  1.256629e-04  1.309829e-04  1.365367e-04
## ASV11210     1.823941e-38  1.188673e-04  1.245885e-04  1.306137e-04
## ASV7585     -3.040027e-38 -1.874130e-04 -1.960541e-04 -2.050039e-04
## ASV8596     -3.040027e-38 -1.874130e-04 -1.960395e-04 -2.049880e-04
## ASV9532     -1.249619e-38 -7.547227e-05 -7.889242e-05 -8.241249e-05
## ASV4254      2.156558e-38  1.354143e-04  1.416887e-04  1.482820e-04
## ASV13299    -3.040027e-38 -1.874130e-04 -1.960264e-04 -2.049739e-04
## ASV15627    -3.040027e-38 -1.874130e-04 -1.960119e-04 -2.049580e-04
## ASV6302     -2.623933e-38 -1.507251e-04 -1.571242e-04 -1.637604e-04
## ASV3040      1.210613e-38  7.535094e-05  7.879265e-05  8.242329e-05
## ASV0632      2.456671e-38  1.532652e-04  1.603883e-04  1.678082e-04
## ASV3694      3.937979e-38  2.440474e-04  2.552869e-04  2.670042e-04
## ASV1592     -8.225889e-39 -4.632693e-05 -4.825360e-05 -5.023747e-05
## ASV0538      1.956246e-38  1.239503e-04  1.298167e-04  1.359266e-04
## ASV0832      4.413547e-38  2.727480e-04  2.852434e-04  2.982982e-04
## ASV0727      3.240024e-38  2.052579e-04  2.149250e-04  2.250274e-04
## ASV1165     -4.243174e-38 -2.643507e-04 -2.765874e-04 -2.893588e-04
## ASV1325      2.978504e-39  2.803269e-05  2.978115e-05  3.165208e-05
## ASV0819      7.624776e-38  4.744835e-04  4.963932e-04  5.192866e-04
## ASV2251      4.388158e-38  2.566459e-04  2.677100e-04  2.792199e-04
## ASV0100     -2.715520e-39 -1.638220e-05 -1.710137e-05 -1.786046e-05
## ASV0444     -2.034690e-38 -1.265031e-04 -1.323313e-04 -1.384380e-04
## ASV0800      1.023374e-37  6.220546e-04  6.500667e-04  6.792950e-04
## ASV2432      3.064522e-39  1.474125e-05  1.520939e-05  1.569978e-05
## ASV2883      3.277645e-39  1.773516e-05  1.842055e-05  1.913062e-05
## ASV3894      4.022887e-39  2.041883e-05  2.113385e-05  2.186825e-05
## ASV2367      7.032013e-38  4.341136e-04  4.539856e-04  4.747399e-04
## ASV3724     -4.210973e-38 -2.582322e-04 -2.701207e-04 -2.823838e-04
## ASV2112     -3.529808e-38 -2.200352e-04 -2.302050e-04 -2.408335e-04
## ASV3661      1.197793e-38  7.595683e-05  7.953518e-05  8.327809e-05
## ASV2096     -2.484148e-38 -1.587756e-04 -1.662946e-04 -1.741611e-04
## ASV3551     -3.048313e-38 -1.851950e-04 -1.935215e-04 -2.022020e-04
## ASV11343    -6.929173e-40 -5.980268e-06 -6.354878e-06 -6.737031e-06
## ASV2051      2.522410e-38  1.579755e-04  1.653165e-04  1.730052e-04
## ASV2617     -3.522060e-38 -2.174484e-04 -2.274342e-04 -2.378318e-04
## ASV0125     -1.539783e-38 -9.611700e-05 -1.005737e-04 -1.052210e-04
## ASV0372      5.367925e-38  3.314375e-04  3.466241e-04  3.624712e-04
## ASV6751     -4.053261e-38 -2.478039e-04 -2.592502e-04 -2.709846e-04
## ASV10810     8.931547e-39  5.541104e-05  5.795288e-05  6.062211e-05
## ASV0461     -2.242560e-38 -1.410224e-04 -1.476074e-04 -1.544898e-04
## ASV1945     -1.310297e-38 -8.348082e-05 -8.743520e-05 -9.156809e-05
## ASV0882     -1.037686e-38 -7.075338e-05 -7.431636e-05 -7.805969e-05
## ASV4040     -5.769967e-39 -3.599195e-05 -3.766859e-05 -3.940140e-05
## ASV0109     -4.721853e-40 -2.523926e-06 -2.615547e-06 -2.712550e-06
## ASV0174      1.933194e-38  1.123340e-04  1.171656e-04  1.221543e-04
## ASV2851      3.199151e-38  1.914681e-04  1.999223e-04  2.087413e-04
## ASV5312      5.312496e-39  3.226341e-05  3.372442e-05  3.525441e-05
## ASV9402     -4.325222e-38 -2.656962e-04 -2.777873e-04 -2.904149e-04
## ASV4870     -3.516589e-38 -2.146671e-04 -2.245437e-04 -2.346891e-04
## ASV0589      4.139692e-38  2.562793e-04  2.680571e-04  2.803480e-04
## ASV1221     -8.777030e-54  5.280853e-07  5.767836e-07  6.286130e-07
## ASV6028     -4.018858e-38 -2.480878e-04 -2.594367e-04 -2.712985e-04
## ASV5106     -1.554329e-38 -9.367488e-05 -9.786305e-05 -1.022199e-04
## ASV4977     -4.326786e-39 -3.279587e-05 -3.459671e-05 -3.648893e-05
## ASV5715     -2.635914e-38 -1.629537e-04 -1.704258e-04 -1.782295e-04
## ASV4182      9.114300e-39  6.084561e-05  6.386204e-05  6.702635e-05
## ASV2383     -1.224025e-39 -1.270653e-05 -1.354493e-05 -1.444057e-05
## ASV3985      4.632261e-38  2.918889e-04  3.055420e-04  3.198213e-04
## ASV2787     -3.657967e-38 -2.204714e-04 -2.305185e-04 -2.407968e-04
## ASV6756     -3.021509e-38 -1.888915e-04 -1.977458e-04 -2.069067e-04
## ASV1634     -4.979796e-38 -3.034941e-04 -3.171843e-04 -3.314799e-04
## ASV0649     -1.484206e-38 -9.262162e-05 -9.692184e-05 -1.014001e-04
## ASV1591     -2.369798e-53 -5.085902e-06 -5.563884e-06 -6.070546e-06
## ASV1854      4.958603e-38  3.134453e-04  3.281545e-04  3.435369e-04
## ASV4205      3.306676e-38  2.090174e-04  2.188216e-04  2.290794e-04
## ASV3293     -1.995820e-38 -1.214188e-04 -1.268846e-04 -1.325933e-04
## ASV1631      2.297533e-38  1.423953e-04  1.489281e-04  1.557697e-04
## ASV1747     -1.242790e-38 -8.049638e-05 -8.436975e-05 -8.842410e-05
## ASV5634      1.045123e-38  6.457672e-05  6.748993e-05  7.058017e-05
## ASV0965     -1.657955e-38 -1.017126e-04 -1.063348e-04 -1.111647e-04
## ASV1094      2.858736e-38  1.754833e-04  1.834833e-04  1.918233e-04
## ASV2744     -1.141014e-53 -5.183182e-06 -5.668809e-06 -6.184766e-06
## ASV7212     -4.215240e-38 -2.651084e-04 -2.774777e-04 -2.904052e-04
## ASV0344     -2.838384e-38 -1.759738e-04 -1.840707e-04 -1.925248e-04
## ASV11812    -3.040027e-38 -1.902559e-04 -1.991710e-04 -2.084081e-04
## ASV7867     -4.133840e-39 -2.735272e-05 -2.875550e-05 -3.016356e-05
## ASV6670      2.913185e-38  1.739218e-04  1.815887e-04  1.895955e-04
## ASV10991     1.901303e-39  4.282246e-06  4.070833e-06  3.875438e-06
## ASV1281      5.335600e-38  3.394320e-04  3.554512e-04  3.722246e-04
## ASV12845    -3.040027e-38 -1.902560e-04 -1.991580e-04 -2.083940e-04
## ASV1833     -3.040027e-38 -1.902560e-04 -1.991429e-04 -2.083776e-04
## ASV2211      2.086413e-38  1.244988e-04  1.299561e-04  1.356765e-04
## ASV3920      4.418922e-38  2.690319e-04  2.811459e-04  2.937978e-04
## ASV4545     -3.448612e-38 -2.161412e-04 -2.262371e-04 -2.367448e-04
## ASV4710     -3.774718e-38 -2.360865e-04 -2.470721e-04 -2.585213e-04
## ASV4978      5.969515e-39  3.759960e-05  3.933642e-05  4.117330e-05
## ASV9630     -9.827452e-40 -6.547209e-06 -6.887962e-06 -7.227387e-06
## ASV9797     -2.502353e-40 -6.088039e-06 -6.609903e-06 -7.146665e-06
## ASV13469    -3.040027e-38 -1.902560e-04 -1.991028e-04 -2.083339e-04
## ASV14961    -1.112200e-38 -6.945500e-05 -7.268035e-05 -7.604133e-05
## ASV6259      1.778413e-38  1.073677e-04  1.121546e-04  1.171544e-04
## ASV6294     -2.162499e-38 -1.354590e-04 -1.417561e-04 -1.483331e-04
## ASV6883     -9.828994e-39 -6.326825e-05 -6.629059e-05 -6.945172e-05
## ASV7041     -2.462302e-38 -1.568967e-04 -1.643071e-04 -1.720637e-04
## ASV4363     -3.040027e-38 -1.849001e-04 -1.934240e-04 -2.021310e-04
## ASV1784     -4.345424e-38 -2.690979e-04 -2.815453e-04 -2.944625e-04
## ASV2140      3.696063e-39  2.398900e-05  2.499772e-05  2.618976e-05
## ASV3202      3.040027e-38  1.849001e-04  1.934005e-04  2.021059e-04
## ASV6017     -3.040027e-38 -1.849001e-04 -1.933862e-04 -2.020905e-04
## ASV9129      1.550687e-38  9.325929e-05  9.734452e-05  1.016606e-04
## ASV0917      3.114227e-38  1.896477e-04  1.983474e-04  2.072871e-04
## ASV10584    -1.190688e-39 -3.106852e-06 -3.148842e-06 -3.084124e-06
## ASV11218     2.001193e-38  1.206135e-04  1.259413e-04  1.315413e-04
## ASV11229     2.084112e-39  1.713119e-05  1.802123e-05  1.905442e-05
## ASV11604    -3.080520e-39 -2.084926e-05 -2.200884e-05 -2.311349e-05
## ASV2103     -3.538295e-38 -2.169844e-04 -2.269763e-04 -2.372863e-04
## ASV2165     -3.040027e-38 -1.849001e-04 -1.933455e-04 -2.020471e-04
## ASV2340      3.467578e-38  2.060139e-04  2.150650e-04  2.244844e-04
## ASV3738     -3.040027e-38 -1.849000e-04 -1.933288e-04 -2.020291e-04
## ASV4012      9.229818e-39  5.621445e-05  5.869138e-05  6.132987e-05
## ASV4094     -3.040027e-38 -1.849000e-04 -1.933168e-04 -2.020162e-04
## ASV4454     -3.040027e-38 -1.849000e-04 -1.933026e-04 -2.020007e-04
## ASV7031      6.628060e-39  4.344030e-05  4.550437e-05  4.771283e-05
## ASV7087     -1.213891e-38 -7.094942e-05 -7.406542e-05 -7.725328e-05
## ASV4159      1.911772e-39  1.101499e-05  1.142154e-05  1.189800e-05
## ASV5084     -3.040027e-38 -1.849000e-04 -1.932864e-04 -2.019833e-04
## ASV6584     -3.040027e-38 -1.849000e-04 -1.932723e-04 -2.019679e-04
## ASV9614     -3.040027e-38 -1.849000e-04 -1.932581e-04 -2.019525e-04
## ASV16068    -3.040027e-38 -1.848999e-04 -1.932440e-04 -2.019371e-04
## ASV2141     -4.170490e-38 -2.466569e-04 -2.574560e-04 -2.686997e-04
## ASV0395     -2.642619e-39 -1.726359e-05 -1.810118e-05 -1.898065e-05
## ASV5640     -6.567418e-39 -4.277969e-05 -4.484505e-05 -4.700632e-05
## ASV2854     -3.441828e-38 -2.080972e-04 -2.174134e-04 -2.271327e-04
## ASV3825     -5.932104e-38 -3.659099e-04 -3.826403e-04 -4.001197e-04
## ASV0481      6.628359e-38  3.997532e-04  4.175919e-04  4.362149e-04
## ASV3304      2.906600e-39  1.854120e-05  1.942008e-05  2.034120e-05
## ASV0445      3.962952e-38  2.428707e-04  2.538954e-04  2.654087e-04
## ASV1845     -2.009961e-38 -1.271652e-04 -1.331353e-04 -1.393782e-04
## ASV3110     -2.302631e-38 -1.407406e-04 -1.471169e-04 -1.537850e-04
##                                                                    
## (Intercept) -2.319684e-06 -2.697601e-06 -3.136104e-06 -3.644604e-06
## ASV1236      2.182917e-04  2.280817e-04  2.382815e-04  2.489060e-04
## ASV0421     -3.830610e-04 -4.001105e-04 -4.178649e-04 -4.363485e-04
## ASV0691     -3.302667e-04 -3.445119e-04 -3.593053e-04 -3.746621e-04
## ASV0899     -5.210495e-07 -1.526746e-07  2.653031e-07  7.376647e-07
## ASV1004      4.359075e-04  4.553409e-04  4.755797e-04  4.966518e-04
## ASV1041     -2.977163e-04 -3.111261e-04 -3.251037e-04 -3.396699e-04
## ASV1058      4.060670e-04  4.242214e-04  4.431340e-04  4.628316e-04
## ASV12542     1.230172e-04  1.283003e-04  1.337850e-04  1.394765e-04
## ASV1294      4.741660e-04  4.955945e-04  5.179381e-04  5.412311e-04
## ASV13113     1.671614e-04  1.748339e-04  1.828456e-04  1.912103e-04
## ASV1318      4.146359e-04  4.333194e-04  4.527948e-04  4.730915e-04
## ASV2269     -1.259508e-04 -1.317380e-04 -1.377790e-04 -1.440839e-04
## ASV2542      2.684095e-04  2.809602e-04  2.940858e-04  3.078117e-04
## ASV2660     -2.396987e-04 -2.504252e-04 -2.615986e-04 -2.732346e-04
## ASV2737     -1.610823e-05 -1.709064e-05 -1.813603e-05 -1.924865e-05
## ASV2840      3.116788e-04  3.252415e-04  3.393360e-04  3.539781e-04
## ASV3053      1.574659e-05  1.635976e-05  1.699213e-05  1.764380e-05
## ASV3077      9.807940e-05  1.024272e-04  1.069548e-04  1.116682e-04
## ASV3134      3.422426e-04  3.581599e-04  3.748007e-04  3.921961e-04
## ASV3140      1.534922e-04  1.607011e-04  1.682405e-04  1.761247e-04
## ASV3579      5.953427e-05  6.243551e-05  6.548196e-05  6.868106e-05
## ASV6119     -1.259295e-04 -1.317147e-04 -1.377535e-04 -1.440559e-04
## ASV7557     -1.259192e-04 -1.317034e-04 -1.377411e-04 -1.440425e-04
## ASV8422      6.398923e-05  6.659433e-05  6.928667e-05  7.206743e-05
## ASV1086     -3.311476e-05 -3.451474e-05 -3.596761e-05 -3.747477e-05
## ASV1310      2.327085e-04  2.431591e-04  2.540504e-04  2.653984e-04
## ASV15750    -6.112393e-05 -6.396011e-05 -6.692201e-05 -7.001470e-05
## ASV16905    -1.259139e-04 -1.316975e-04 -1.377347e-04 -1.440353e-04
## ASV2033      2.269755e-04  2.373029e-04  2.480785e-04  2.593197e-04
## ASV2089      8.680023e-05  9.082145e-05  9.502130e-05  9.940705e-05
## ASV2127      3.325033e-04  3.472551e-04  3.626116e-04  3.785931e-04
## ASV2725      3.777564e-04  3.943899e-04  4.116952e-04  4.296941e-04
## ASV2804     -1.259103e-04 -1.316935e-04 -1.377302e-04 -1.440304e-04
## ASV3075      2.382653e-04  2.488922e-04  2.599615e-04  2.714890e-04
## ASV3327      2.239430e-04  2.341905e-04  2.448886e-04  2.560555e-04
## ASV3342      2.489022e-04  2.604134e-04  2.724392e-04  2.850008e-04
## ASV3532     -2.234480e-04 -2.337091e-04 -2.444217e-04 -2.556036e-04
## ASV3600      2.788692e-04  2.914685e-04  3.046069e-04  3.183050e-04
## ASV4013      2.341051e-04  2.445241e-04  2.553739e-04  2.666693e-04
## ASV4136      2.359898e-04  2.465471e-04  2.575447e-04  2.689985e-04
## ASV4195      1.258945e-04  1.316762e-04  1.377113e-04  1.440097e-04
## ASV4407     -1.258842e-04 -1.316649e-04 -1.376989e-04 -1.439962e-04
## ASV4717      2.439400e-06  2.263318e-06  2.055778e-06  1.813577e-06
## ASV6794      1.223613e-04  1.275167e-04  1.328606e-04  1.383974e-04
## ASV8324     -1.258800e-04 -1.316603e-04 -1.376938e-04 -1.439904e-04
## ASV8981     -3.619920e-05 -3.784221e-05 -3.955418e-05 -4.133747e-05
## ASV9859      9.312318e-05  9.753908e-05  1.021644e-04  1.070089e-04
## ASV0936     -1.909995e-04 -1.995217e-04 -2.083994e-04 -2.176453e-04
## ASV12683    -2.285762e-05 -2.408837e-05 -2.538788e-05 -2.676008e-05
## ASV1293      2.835249e-04  2.961300e-04  3.092530e-04  3.229113e-04
## ASV13055    -3.272844e-05 -3.426895e-05 -3.587879e-05 -3.756073e-05
## ASV17063    -1.258612e-04 -1.316397e-04 -1.376713e-04 -1.439658e-04
## ASV2228      1.258509e-04  1.316284e-04  1.376589e-04  1.439524e-04
## ASV2769     -2.624090e-05 -2.745874e-05 -2.873004e-05 -3.005684e-05
## ASV2803      5.357652e-05  5.567301e-05  5.783156e-05  6.005219e-05
## ASV2896      1.515586e-04  1.583518e-04  1.654323e-04  1.728108e-04
## ASV3062      4.537112e-05  4.753060e-05  4.979347e-05  5.216469e-05
## ASV3107      1.842541e-04  1.925894e-04  2.012828e-04  2.103478e-04
## ASV3265      3.670591e-04  3.833001e-04  4.002029e-04  4.177892e-04
## ASV3666     -1.043790e-05 -1.101496e-05 -1.162473e-05 -1.226906e-05
## ASV4497      8.637092e-05  9.018864e-05  9.416343e-05  9.830078e-05
## ASV6914     -4.717457e-05 -4.951850e-05 -5.198000e-05 -5.456491e-05
## ASV0576     -4.319348e-04 -4.507332e-04 -4.702708e-04 -4.905697e-04
## ASV0673      1.160165e-04  1.215920e-04  1.274356e-04  1.335598e-04
## ASV0772      1.284531e-04  1.340952e-04  1.399653e-04  1.460708e-04
## ASV0862     -1.048332e-04 -1.093180e-04 -1.139726e-04 -1.188014e-04
## ASV0898      1.109390e-04  1.162319e-04  1.217754e-04  1.275811e-04
## ASV0910      2.395352e-04  2.508413e-04  2.626754e-04  2.750615e-04
## ASV0964     -1.568988e-04 -1.637997e-04 -1.709795e-04 -1.784473e-04
## ASV10059     1.099020e-04  1.150343e-04  1.204033e-04  1.260197e-04
## ASV10263    -1.259004e-04 -1.316823e-04 -1.377176e-04 -1.440163e-04
## ASV1088      1.262081e-04  1.321308e-04  1.383274e-04  1.448103e-04
## ASV1101      2.130047e-04  2.226314e-04  2.326694e-04  2.431343e-04
## ASV1183      1.405123e-04  1.470994e-04  1.539881e-04  1.611913e-04
## ASV11956     4.866853e-05  5.053205e-05  5.244656e-05  5.441160e-05
## ASV12774    -2.286932e-05 -2.414649e-05 -2.549865e-05 -2.693028e-05
## ASV1321      5.337510e-05  5.599344e-05  5.874303e-05  6.163056e-05
## ASV13793    -1.258867e-04 -1.316673e-04 -1.377011e-04 -1.439981e-04
## ASV14482    -1.468614e-05 -1.556304e-05 -1.649470e-05 -1.748452e-05
## ASV15483     8.261678e-05  8.624075e-05  9.001111e-05  9.393276e-05
## ASV2062      5.439753e-04  5.686629e-04  5.944148e-04  6.212718e-04
## ASV2132      2.435198e-04  2.545555e-04  2.660667e-04  2.780719e-04
## ASV2413      3.486350e-04  3.641590e-04  3.803267e-04  3.971607e-04
## ASV2490      2.305836e-04  2.407889e-04  2.514106e-04  2.624629e-04
## ASV2594      1.239246e-04  1.294222e-04  1.351476e-04  1.411093e-04
## ASV2822     -1.259008e-04 -1.316825e-04 -1.377177e-04 -1.440161e-04
## ASV2863      2.161760e-04  2.258938e-04  2.360209e-04  2.465720e-04
## ASV2910      2.745737e-04  2.865773e-04  2.990579e-04  3.120305e-04
## ASV2980      1.043596e-04  1.091493e-04  1.141482e-04  1.193645e-04
## ASV3307      1.258827e-04  1.316627e-04  1.376960e-04  1.439923e-04
## ASV3474      1.928365e-04  2.018587e-04  2.112962e-04  2.211675e-04
## ASV3502      3.976312e-04  4.155252e-04  4.341775e-04  4.536160e-04
## ASV4236      2.010881e-04  2.099144e-04  2.190949e-04  2.286408e-04
## ASV4842     -7.042209e-05 -7.375466e-05 -7.724110e-05 -8.088798e-05
## ASV4894     -1.258929e-04 -1.316738e-04 -1.377081e-04 -1.440055e-04
## ASV5290      1.499551e-04  1.567100e-04  1.637526e-04  1.710936e-04
## ASV5501      2.694885e-05  2.811383e-05  2.932575e-05  3.058633e-05
## ASV5795      9.959803e-05  1.041039e-04  1.088041e-04  1.137064e-04
## ASV5987     -1.258958e-04 -1.316770e-04 -1.377115e-04 -1.440093e-04
## ASV6267     -1.258855e-04 -1.316657e-04 -1.376992e-04 -1.439958e-04
## ASV6862      2.337131e-04  2.438409e-04  2.543634e-04  2.652920e-04
## ASV7145      4.023792e-05  4.182716e-05  4.346557e-05  4.515356e-05
## ASV7673     -1.258819e-04 -1.316617e-04 -1.376948e-04 -1.439909e-04
## ASV7789      4.202687e-05  4.401372e-05  4.609482e-05  4.827469e-05
## ASV7809     -1.848065e-05 -1.933905e-05 -2.023451e-05 -2.116828e-05
## ASV8002     -1.258732e-04 -1.316522e-04 -1.376844e-04 -1.439796e-04
## ASV8205      6.597208e-05  6.872000e-05  7.156571e-05  7.451130e-05
## ASV9155     -9.550971e-05 -9.990765e-05 -1.044989e-04 -1.092909e-04
## ASV9221     -2.022522e-05 -2.128453e-05 -2.240081e-05 -2.357710e-05
## ASV9311     -1.258575e-04 -1.316350e-04 -1.376655e-04 -1.439589e-04
## ASV9557     -1.258472e-04 -1.316238e-04 -1.376532e-04 -1.439454e-04
## ASV9936     -1.258369e-04 -1.316125e-04 -1.376409e-04 -1.439319e-04
## ASV1445      2.832820e-04  2.962423e-04  3.097714e-04  3.238922e-04
## ASV4232      2.369284e-04  2.477997e-04  2.591525e-04  2.710069e-04
## ASV6479     -2.458459e-06 -2.391291e-06 -2.302759e-06 -2.190094e-06
## ASV0142     -6.171050e-04 -6.443356e-04 -6.726708e-04 -7.021468e-04
## ASV0378     -2.029552e-04 -2.118412e-04 -2.210810e-04 -2.306854e-04
## ASV1122      3.729635e-04  3.899763e-04  4.077313e-04  4.262578e-04
## ASV0123     -6.049047e-04 -6.315983e-04 -6.593747e-04 -6.882696e-04
## ASV2064      6.015238e-05  6.261891e-05  6.517087e-05  6.781002e-05
## ASV4459     -7.104609e-05 -7.437216e-05 -7.784898e-05 -8.148277e-05
## ASV0448      1.125182e-04  1.181838e-04  1.241428e-04  1.304105e-04
## ASV0397      2.823977e-04  2.953441e-04  3.088587e-04  3.229640e-04
## ASV0485      3.920669e-04  4.097469e-04  4.281777e-04  4.473872e-04
## ASV1566      3.239275e-04  3.384711e-04  3.536281e-04  3.694211e-04
## ASV1365      2.085411e-04  2.178633e-04  2.275753e-04  2.376910e-04
## ASV1065      4.347431e-04  4.544840e-04  4.750755e-04  4.965500e-04
## ASV0722     -6.927010e-06 -7.103724e-06 -7.277438e-06 -7.447330e-06
## ASV12660    -2.082935e-04 -2.176633e-04 -2.274278e-04 -2.376012e-04
## ASV0223     -3.014279e-06 -2.897018e-06 -2.752447e-06 -2.577624e-06
## ASV0229      1.964505e-04  2.055547e-04  2.150674e-04  2.250056e-04
## ASV0877     -7.729602e-05 -8.075619e-05 -8.436001e-05 -8.811237e-05
## ASV0983      4.003367e-04  4.183208e-04  4.370620e-04  4.565876e-04
## ASV0626     -1.304188e-04 -1.358905e-04 -1.415573e-04 -1.474232e-04
## ASV4146     -2.489523e-05 -2.611080e-05 -2.738494e-05 -2.872026e-05
## ASV4175     -2.466988e-04 -2.579545e-04 -2.696989e-04 -2.819510e-04
## ASV2082     -1.405664e-05 -1.469089e-05 -1.535399e-05 -1.604742e-05
## ASV2272      1.755098e-04  1.835059e-04  1.918511e-04  2.005594e-04
## ASV2245     -2.140410e-04 -2.238144e-04 -2.340126e-04 -2.446521e-04
## ASV0590     -1.262572e-04 -1.321080e-04 -1.382230e-04 -1.446133e-04
## ASV0217     -1.926714e-04 -2.004020e-04 -2.083740e-04 -2.165887e-04
## ASV0416      2.006759e-04  2.094491e-04  2.185691e-04  2.280461e-04
## ASV1056      2.372542e-04  2.483487e-04  2.599514e-04  2.720847e-04
## ASV7777     -2.156313e-04 -2.256057e-04 -2.360259e-04 -2.469100e-04
## ASV0455      4.464943e-05  4.685355e-05  4.916723e-05  5.159574e-05
## ASV0604      4.892148e-05  5.152712e-05  5.428049e-05  5.719047e-05
## ASV6100     -2.004239e-04 -2.097752e-04 -2.195518e-04 -2.297718e-04
## ASV11359    -2.199797e-04 -2.299674e-04 -2.403840e-04 -2.512458e-04
## ASV6604      1.564005e-04  1.636790e-04  1.712894e-04  1.792463e-04
## ASV5004     -1.314766e-04 -1.375422e-04 -1.438766e-04 -1.504903e-04
## ASV1483     -1.200611e-04 -1.255684e-04 -1.313168e-04 -1.373159e-04
## ASV9773     -2.548936e-04 -2.666834e-04 -2.790003e-04 -2.918661e-04
## ASV4059      2.532799e-05  2.671508e-05  2.818540e-05  2.974449e-05
## ASV1193      4.089676e-04  4.276056e-04  4.470557e-04  4.673498e-04
## ASV4610     -3.795527e-05 -3.946309e-05 -4.101534e-05 -4.261174e-05
## ASV0742     -1.539368e-04 -1.605530e-04 -1.674204e-04 -1.745456e-04
## ASV1502     -2.473531e-06 -2.708671e-06 -2.963442e-06 -3.239217e-06
## ASV0195     -4.405599e-05 -4.620573e-05 -4.846244e-05 -5.083158e-05
## ASV1213      1.323947e-04  1.383292e-04  1.445118e-04  1.509512e-04
## ASV1648     -1.893023e-04 -1.980655e-04 -2.072212e-04 -2.167856e-04
## ASV6984     -1.402608e-04 -1.467138e-04 -1.534513e-04 -1.604847e-04
## ASV0396     -9.947357e-05 -1.031735e-04 -1.069609e-04 -1.108331e-04
## ASV4297      2.076864e-04  2.168104e-04  2.263015e-04  2.361717e-04
## ASV2622      4.750497e-04  4.961690e-04  5.181597e-04  5.410517e-04
## ASV3512      7.107573e-05  7.446321e-05  7.801330e-05  8.173396e-05
## ASV2411      1.649240e-04  1.726475e-04  1.807255e-04  1.891735e-04
## ASV2291     -3.744527e-05 -3.912270e-05 -4.087186e-05 -4.269563e-05
## ASV0807      1.971101e-04  2.066925e-04  2.167448e-04  2.272901e-04
## ASV1292      1.117384e-04  1.169088e-04  1.223108e-04  1.279537e-04
## ASV1035      5.036177e-05  5.250326e-05  5.472305e-05  5.702276e-05
## ASV0070     -1.138918e-04 -1.187632e-04 -1.238185e-04 -1.290624e-04
## ASV0255      4.412049e-05  4.601178e-05  4.797265e-05  5.000444e-05
## ASV0057     -4.890102e-04 -5.103964e-04 -5.326314e-04 -5.557412e-04
## ASV0077     -7.242739e-05 -7.544363e-05 -7.856678e-05 -8.179908e-05
## ASV0625      4.922102e-04  5.141885e-04  5.370812e-04  5.609203e-04
## ASV2464      2.407406e-04  2.514677e-04  2.626381e-04  2.742670e-04
## ASV1315      4.191005e-04  4.381828e-04  4.580960e-04  4.788731e-04
## ASV2673      3.133837e-04  3.280911e-04  3.434770e-04  3.595718e-04
## ASV2161      1.269694e-04  1.328668e-04  1.390322e-04  1.454772e-04
## ASV0337     -2.066330e-04 -2.160410e-04 -2.258584e-04 -2.361016e-04
## ASV7680     -2.414752e-04 -2.525038e-04 -2.640124e-04 -2.760198e-04
## ASV0611      5.216099e-04  5.454961e-04  5.704327e-04  5.964619e-04
## ASV3118     -1.791460e-04 -1.874075e-04 -1.960355e-04 -2.050449e-04
## ASV1284      1.949473e-04  2.041646e-04  2.138090e-04  2.238988e-04
## ASV0889      1.417984e-04  1.481130e-04  1.546900e-04  1.615385e-04
## ASV4649     -1.529504e-04 -1.600504e-04 -1.674700e-04 -1.752224e-04
## ASV1108     -1.943588e-04 -2.035645e-04 -2.132012e-04 -2.232883e-04
## ASV0738     -2.395171e-05 -2.421644e-05 -2.441782e-05 -2.454670e-05
## ASV0473      3.038503e-05  3.180966e-05  3.329924e-05  3.485651e-05
## ASV0598     -2.172774e-04 -2.268131e-04 -2.367307e-04 -2.470422e-04
## ASV0429      3.455799e-04  3.611171e-04  3.773107e-04  3.941847e-04
## ASV1549      3.479274e-04  3.642571e-04  3.813412e-04  3.992133e-04
## ASV1203      2.595382e-04  2.711674e-04  2.832836e-04  2.959042e-04
## ASV4532      1.100382e-05  1.140281e-05  1.181141e-05  1.222954e-05
## ASV0274     -2.586574e-04 -2.698413e-04 -2.814593e-04 -2.935240e-04
## ASV0163     -3.722728e-04 -3.884363e-04 -4.052310e-04 -4.226751e-04
## ASV1298      1.522088e-04  1.588475e-04  1.657474e-04  1.729162e-04
## ASV9424     -3.227792e-04 -3.377118e-04 -3.533128e-04 -3.696099e-04
## ASV0412      4.926992e-04  5.149168e-04  5.380785e-04  5.622195e-04
## ASV0284      2.186597e-04  2.282138e-04  2.381454e-04  2.484658e-04
## ASV0620     -1.664428e-04 -1.743127e-04 -1.825491e-04 -1.911683e-04
## ASV0153     -3.413759e-04 -3.571274e-04 -3.735827e-04 -3.907713e-04
## ASV0498      3.944744e-05  4.177048e-05  4.423973e-05  4.686462e-05
## ASV0097      2.425326e-04  2.536756e-04  2.653118e-04  2.774611e-04
## ASV0104     -1.129196e-03 -1.180212e-03 -1.233409e-03 -1.288869e-03
## ASV1282      1.996515e-04  2.088987e-04  2.185597e-04  2.286518e-04
## ASV3883     -1.114352e-04 -1.164760e-04 -1.217306e-04 -1.272066e-04
## ASV0801      1.180196e-04  1.238102e-04  1.298894e-04  1.362718e-04
## ASV1611     -4.334412e-04 -4.531687e-04 -4.737505e-04 -4.952196e-04
## ASV0227     -1.537602e-04 -1.608675e-04 -1.682928e-04 -1.760492e-04
## ASV0833      1.706419e-04  1.787733e-04  1.872902e-04  1.962105e-04
## ASV0718      4.098356e-04  4.286785e-04  4.483565e-04  4.689037e-04
## ASV1139      1.535994e-04  1.604479e-04  1.675800e-04  1.750054e-04
## ASV0766     -1.091714e-04 -1.139457e-04 -1.189085e-04 -1.240652e-04
## ASV2091      5.397119e-04  5.634211e-04  5.880834e-04  6.137292e-04
## ASV1238     -2.761769e-05 -2.827988e-05 -2.892023e-05 -2.953379e-05
## ASV9193     -5.910331e-05 -6.246991e-05 -6.603847e-05 -6.982116e-05
## ASV0290     -4.190559e-05 -4.382430e-05 -4.582645e-05 -4.791519e-05
## ASV0231      4.264836e-04  4.455525e-04  4.654165e-04  4.861036e-04
## ASV0185      8.243342e-05  8.734513e-05  9.257475e-05  9.814400e-05
## ASV2330      1.240608e-04  1.295709e-04  1.353082e-04  1.412804e-04
## ASV3119     -1.434664e-04 -1.504577e-04 -1.577933e-04 -1.654901e-04
## ASV2368     -1.986988e-04 -2.080293e-04 -2.177900e-04 -2.280001e-04
## ASV0122     -1.562101e-04 -1.631724e-04 -1.704255e-04 -1.779801e-04
## ASV1044      2.735318e-04  2.866016e-04  3.002961e-04  3.146450e-04
## ASV0160     -3.784025e-04 -3.947886e-04 -4.118111e-04 -4.294885e-04
## ASV0326      2.463787e-04  2.575648e-04  2.692335e-04  2.814034e-04
## ASV1388      4.311879e-04  4.506418e-04  4.709244e-04  4.920666e-04
## ASV0792      4.943390e-04  5.166722e-04  5.399587e-04  5.642340e-04
## ASV0036     -3.126149e-04 -3.271504e-04 -3.423454e-04 -3.582284e-04
## ASV2125      5.074101e-04  5.304463e-04  5.544773e-04  5.795416e-04
## ASV1075      9.695802e-05  1.015071e-04  1.062675e-04  1.112490e-04
## ASV0390      1.000860e-04  1.051964e-04  1.105802e-04  1.162529e-04
## ASV3790     -3.976255e-04 -4.153902e-04 -4.338949e-04 -4.531657e-04
## ASV1535     -3.383239e-05 -3.549750e-05 -3.724404e-05 -3.907568e-05
## ASV0263      8.661457e-05  9.068439e-05  9.494197e-05  9.939556e-05
## ASV0675      6.735378e-04  7.049750e-04  7.378465e-04  7.722142e-04
## ASV3348      6.553131e-05  6.873222e-05  7.209261e-05  7.562065e-05
## ASV0058     -6.337618e-04 -6.621702e-04 -6.917732e-04 -7.226142e-04
## ASV4142      1.562660e-04  1.631320e-04  1.702742e-04  1.777015e-04
## ASV0059     -5.462487e-04 -5.706799e-04 -5.961337e-04 -6.226467e-04
## ASV0013     -1.144833e-03 -1.196479e-03 -1.250326e-03 -1.306456e-03
## ASV0033     -3.410020e-04 -3.569115e-04 -3.735476e-04 -3.909421e-04
## ASV4354     -1.473325e-04 -1.538765e-04 -1.606893e-04 -1.677802e-04
## ASV0022     -3.600688e-04 -3.768544e-04 -3.944053e-04 -4.127547e-04
## ASV0134     -9.171663e-05 -9.625127e-05 -1.010162e-04 -1.060236e-04
## ASV0415     -7.385864e-05 -7.681176e-05 -7.985743e-05 -8.299630e-05
## ASV10103    -2.491589e-04 -2.605566e-04 -2.724532e-04 -2.848683e-04
## ASV1613      4.054657e-04  4.237587e-04  4.428314e-04  4.627131e-04
## ASV0135     -2.487630e-05 -2.568630e-05 -2.650133e-05 -2.731878e-05
## ASV0469     -5.037471e-04 -5.262996e-04 -5.497964e-04 -5.742714e-04
## ASV0471      3.245378e-04  3.395527e-04  3.552392e-04  3.716251e-04
## ASV0451     -8.697313e-05 -9.114166e-05 -9.551140e-05 -1.000922e-04
## ASV0747      1.206897e-04  1.262557e-04  1.320685e-04  1.381382e-04
## ASV1314     -1.922646e-04 -2.014069e-04 -2.109808e-04 -2.210063e-04
## ASV0425     -5.687602e-04 -5.938285e-04 -6.199118e-04 -6.470435e-04
## ASV0559     -3.203629e-04 -3.342994e-04 -3.487829e-04 -3.638299e-04
## ASV0148     -3.501057e-04 -3.654367e-04 -3.813795e-04 -3.979533e-04
## ASV0129     -1.737363e-04 -1.810763e-04 -1.886857e-04 -1.965710e-04
## ASV1072      1.684197e-04  1.756871e-04  1.832355e-04  1.910732e-04
## ASV2390      1.227093e-04  1.281212e-04  1.337522e-04  1.396093e-04
## ASV0548      3.700480e-04  3.870718e-04  4.048523e-04  4.234208e-04
## ASV0168     -5.494889e-04 -5.739226e-04 -5.993659e-04 -6.258541e-04
## ASV0066     -4.125166e-04 -4.311909e-04 -4.506669e-04 -4.709753e-04
## ASV0468     -1.578575e-04 -1.653121e-04 -1.731149e-04 -1.812819e-04
## ASV0172     -8.514247e-05 -8.848510e-05 -9.192662e-05 -9.546704e-05
## ASV0236     -2.098058e-04 -2.184835e-04 -2.274610e-04 -2.367434e-04
## ASV0250      1.408227e-05  1.560642e-05  1.727422e-05  1.909783e-05
## ASV0338     -2.307367e-05 -2.338215e-05 -2.363945e-05 -2.383821e-05
## ASV0450      9.981357e-07  1.186206e-06  1.395265e-06  1.627258e-06
## ASV0377      4.536758e-04  4.743454e-04  4.959136e-04  5.184157e-04
## ASV1022      1.289362e-04  1.349744e-04  1.412901e-04  1.478957e-04
## ASV6174     -2.849229e-05 -2.960781e-05 -3.075436e-05 -3.193147e-05
## ASV0786      5.183651e-05  5.411941e-05  5.649393e-05  5.896291e-05
## ASV0053     -5.445022e-04 -5.693179e-04 -5.952138e-04 -6.222325e-04
## ASV0697     -1.566676e-04 -1.634762e-04 -1.705522e-04 -1.779037e-04
## ASV0785      4.047074e-04  4.231251e-04  4.423445e-04  4.623974e-04
## ASV1967     -2.700081e-04 -2.820443e-04 -2.945795e-04 -3.076311e-04
## ASV0385     -1.225874e-04 -1.278191e-04 -1.332496e-04 -1.388845e-04
## ASV0295      1.396888e-07  5.039558e-07  9.162689e-07  1.381348e-06
## ASV0072     -4.321479e-04 -4.512681e-04 -4.711706e-04 -4.918818e-04
## ASV0157     -1.752872e-04 -1.826266e-04 -1.902252e-04 -1.980875e-04
## ASV0501      2.009594e-04  2.104838e-04  2.204516e-04  2.308823e-04
## ASV10729    -3.332345e-04 -3.485738e-04 -3.645934e-04 -3.813207e-04
## ASV1470      1.480746e-04  1.542621e-04  1.606707e-04  1.673052e-04
## ASV0050     -1.080391e-03 -1.128878e-03 -1.179410e-03 -1.232058e-03
## ASV0411     -2.962727e-05 -3.088136e-05 -3.218379e-05 -3.353624e-05
## ASV0549      2.071825e-04  2.169324e-04  2.271365e-04  2.378156e-04
## ASV0184      1.280127e-04  1.338759e-04  1.399968e-04  1.463859e-04
## ASV0705      1.561034e-04  1.634807e-04  1.712019e-04  1.792824e-04
## ASV1715      3.848537e-04  4.023886e-04  4.206864e-04  4.397773e-04
## ASV0603      4.918044e-05  5.164243e-05  5.423200e-05  5.695606e-05
## ASV0826      1.284344e-04  1.340730e-04  1.399375e-04  1.460351e-04
## ASV0034     -4.908479e-04 -5.128242e-04 -5.357201e-04 -5.595685e-04
## ASV0838      1.155724e-04  1.213136e-04  1.273449e-04  1.336807e-04
## ASV0614     -2.844597e-04 -2.974992e-04 -3.111132e-04 -3.253249e-04
## ASV0014     -1.047930e-03 -1.095032e-03 -1.144125e-03 -1.195283e-03
## ASV0585     -6.068838e-05 -6.323978e-05 -6.588350e-05 -6.862161e-05
## ASV0016     -1.071602e-03 -1.119805e-03 -1.170049e-03 -1.222409e-03
## ASV5394     -2.758174e-04 -2.885570e-04 -3.018656e-04 -3.157667e-04
## ASV0666      2.329695e-04  2.435199e-04  2.545226e-04  2.659947e-04
## ASV2085      9.123468e-05  9.490276e-05  9.868693e-05  1.025880e-04
## ASV0003     -9.800633e-04 -1.024054e-03 -1.069898e-03 -1.117665e-03
## ASV0346     -1.668266e-05 -1.687356e-05 -1.702215e-05 -1.712243e-05
## ASV0267     -1.593004e-04 -1.664062e-04 -1.738071e-04 -1.815136e-04
## ASV0353      2.139515e-04  2.243032e-04  2.351563e-04  2.465344e-04
## ASV2419      2.780585e-04  2.905414e-04  3.035508e-04  3.171057e-04
## ASV0447      1.329120e-04  1.395226e-04  1.464699e-04  1.537713e-04
## ASV0654      4.278313e-04  4.473655e-04  4.677518e-04  4.890236e-04
## ASV0151      6.695693e-05  7.033498e-05  7.389054e-05  7.763341e-05
## ASV0065     -3.959430e-04 -4.137970e-04 -4.324122e-04 -4.518173e-04
## ASV0527      2.900561e-04  3.033068e-04  3.171372e-04  3.315702e-04
## ASV4055     -1.139870e-04 -1.196289e-04 -1.255578e-04 -1.317887e-04
## ASV0166     -3.216133e-04 -3.354706e-04 -3.498606e-04 -3.647982e-04
## ASV0417     -2.781549e-04 -2.905705e-04 -3.035029e-04 -3.169702e-04
## ASV0078     -2.227343e-04 -2.325603e-04 -2.427859e-04 -2.534245e-04
## ASV0322     -2.662265e-04 -2.777399e-04 -2.897005e-04 -3.021213e-04
## ASV0156     -3.445367e-04 -3.595146e-04 -3.750810e-04 -3.912537e-04
## ASV0648     -3.228564e-04 -3.378308e-04 -3.534794e-04 -3.698306e-04
## ASV0407      1.800240e-05  1.865225e-05  1.931582e-05  1.999247e-05
## ASV2030     -6.715396e-05 -6.994706e-05 -7.283736e-05 -7.582649e-05
## ASV0300      1.931530e-04  2.025538e-04  2.124161e-04  2.227624e-04
## ASV1150     -2.725171e-05 -2.849157e-05 -2.978487e-05 -3.113363e-05
## ASV0958      1.980461e-04  2.075392e-04  2.174884e-04  2.279157e-04
## ASV0216     -3.392103e-04 -3.543166e-04 -3.700474e-04 -3.864241e-04
## ASV0446      4.720229e-04  4.941524e-04  5.172993e-04  5.415080e-04
## ASV0367     -1.602296e-04 -1.674452e-04 -1.749672e-04 -1.828068e-04
## ASV0200     -2.939802e-04 -3.071144e-04 -3.207988e-04 -3.350534e-04
## ASV0334     -1.482709e-04 -1.541213e-04 -1.601450e-04 -1.663418e-04
## ASV1311      2.178999e-04  2.280133e-04  2.385843e-04  2.496323e-04
## ASV0458      2.287780e-04  2.391232e-04  2.499116e-04  2.611600e-04
## ASV1371      3.557794e-06  3.580721e-06  3.591808e-06  3.589415e-06
## ASV0418      2.688763e-04  2.806498e-04  2.928934e-04  3.056218e-04
## ASV0004      3.274057e-04  3.420861e-04  3.573840e-04  3.733216e-04
## ASV1943      2.402449e-04  2.509073e-04  2.620084e-04  2.735634e-04
## ASV1495     -5.967808e-05 -6.270760e-05 -6.589689e-05 -6.925470e-05
## ASV0901     -3.789871e-04 -3.965833e-04 -4.149754e-04 -4.341974e-04
## ASV0628      2.227915e-04  2.328593e-04  2.433579e-04  2.543037e-04
## ASV0400      8.745943e-05  9.131641e-05  9.532807e-05  9.949913e-05
## ASV0116     -2.826392e-04 -2.954787e-04 -3.088735e-04 -3.228452e-04
## ASV0788      2.378475e-04  2.486170e-04  2.598486e-04  2.715600e-04
## ASV0117      1.536947e-04  1.609395e-04  1.685219e-04  1.764573e-04
## ASV3137      4.255571e-05  4.448248e-05  4.649271e-05  4.858977e-05
## ASV0001      3.991065e-04  4.169243e-04  4.354857e-04  4.548172e-04
## ASV1651      2.553356e-04  2.662082e-04  2.774853e-04  2.891767e-04
## ASV1692      2.847351e-04  2.980890e-04  3.120581e-04  3.266698e-04
## ASV0660      1.615598e-04  1.685382e-04  1.757837e-04  1.833032e-04
## ASV0508      2.146879e-05  2.238307e-05  2.333113e-05  2.431373e-05
## ASV1660     -1.150889e-04 -1.204753e-04 -1.261079e-04 -1.319973e-04
## ASV0233      6.488785e-05  6.798051e-05  7.122104e-05  7.461656e-05
## ASV1343     -2.847176e-04 -2.977572e-04 -3.113695e-04 -3.255776e-04
## ASV0209      2.682625e-04  2.803365e-04  2.929232e-04  3.060420e-04
## ASV0193     -3.333672e-04 -3.478113e-04 -3.628188e-04 -3.784062e-04
## ASV0357     -2.576605e-05 -2.690465e-05 -2.808799e-05 -2.931718e-05
## ASV0198      7.676214e-05  8.043679e-05  8.428626e-05  8.831864e-05
## ASV0007      3.790424e-04  3.959975e-04  4.136632e-04  4.320652e-04
## ASV1772     -3.739713e-05 -3.901561e-05 -4.069648e-05 -4.244145e-05
## ASV0009      3.579861e-04  3.739947e-04  3.906739e-04  4.080480e-04
## ASV0006      1.435079e-04  1.496478e-04  1.560199e-04  1.626303e-04
## ASV0011     -3.985095e-04 -4.168622e-04 -4.360299e-04 -4.560460e-04
## ASV0015      2.759564e-04  2.883828e-04  3.013366e-04  3.148373e-04
## ASV0017      2.922412e-04  3.053822e-04  3.190793e-04  3.333531e-04
## ASV0235     -2.302313e-04 -2.406955e-04 -2.516106e-04 -2.629936e-04
## ASV0382      4.483035e-05  4.742153e-05  5.017346e-05  5.309647e-05
## ASV2357      3.510328e-04  3.669709e-04  3.835967e-04  4.009365e-04
## ASV0567     -2.566824e-04 -2.682330e-04 -2.802740e-04 -2.928239e-04
## ASV0165      2.824909e-04  2.953896e-04  3.088508e-04  3.228966e-04
## ASV0005      5.596413e-04  5.845493e-04  6.104876e-04  6.374922e-04
## ASV0384     -2.983630e-05 -3.109618e-05 -3.240196e-05 -3.375466e-05
## ASV0002      1.185841e-04  1.240492e-04  1.297574e-04  1.357185e-04
## ASV3017      3.278666e-04  3.424349e-04  3.576037e-04  3.733936e-04
## ASV0091      1.259982e-04  1.317957e-04  1.378497e-04  1.441707e-04
## ASV0186     -3.360265e-04 -3.512038e-04 -3.670285e-04 -3.835247e-04
## ASV0370      3.668371e-05  3.852375e-05  4.045999e-05  4.249781e-05
## ASV0018      5.830333e-04  6.090358e-04  6.361189e-04  6.643206e-04
## ASV1377      5.123445e-04  5.352741e-04  5.591623e-04  5.840434e-04
## ASV0019      5.838414e-04  6.098875e-04  6.370168e-04  6.652674e-04
## ASV0023      4.164852e-05  4.317469e-05  4.473475e-05  4.632731e-05
## ASV2194      1.883935e-04  1.969542e-04  2.058874e-04  2.152082e-04
## ASV1155     -1.788088e-05 -1.833575e-05 -1.877803e-05 -1.920439e-05
## ASV0510     -2.100245e-04 -2.188060e-04 -2.279005e-04 -2.373144e-04
## ASV2371     -2.117179e-04 -2.209612e-04 -2.305699e-04 -2.405552e-04
## ASV0024      1.343038e-05  1.367518e-05  1.389852e-05  1.409683e-05
## ASV2452      2.765858e-04  2.888482e-04  3.016140e-04  3.149003e-04
## ASV2332      5.114138e-06  5.342476e-06  5.581743e-06  5.832650e-06
## ASV2591      1.134690e-05  1.219500e-05  1.310960e-05  1.409590e-05
## ASV0521      3.856004e-04  4.037781e-04  4.228002e-04  4.427046e-04
## ASV5542      1.154753e-04  1.208476e-04  1.264633e-04  1.323327e-04
## ASV0336     -1.694828e-04 -1.767893e-04 -1.843773e-04 -1.922547e-04
## ASV10102     2.603128e-04  2.721769e-04  2.845562e-04  2.974709e-04
## ASV16823    -2.072881e-04 -2.163884e-04 -2.258534e-04 -2.356947e-04
## ASV3104      2.072719e-04  2.163708e-04  2.258342e-04  2.356738e-04
## ASV0781      1.028848e-04  1.076684e-04  1.126689e-04  1.178959e-04
## ASV10899     9.512916e-05  9.977107e-05  1.046425e-04  1.097548e-04
## ASV11222    -2.072611e-04 -2.163591e-04 -2.258215e-04 -2.356600e-04
## ASV11327    -2.072449e-04 -2.163415e-04 -2.258023e-04 -2.356391e-04
## ASV12458    -2.072287e-04 -2.163238e-04 -2.257831e-04 -2.356182e-04
## ASV1636     -1.678410e-04 -1.751142e-04 -1.826698e-04 -1.905161e-04
## ASV1890     -2.058203e-04 -2.148928e-04 -2.243324e-04 -2.341509e-04
## ASV2898      4.461011e-04  4.662233e-04  4.872018e-04  5.090686e-04
## ASV8328     -3.422867e-05 -3.533666e-05 -3.645222e-05 -3.757205e-05
## ASV0709     -3.614010e-04 -3.776005e-04 -3.944801e-04 -4.120644e-04
## ASV0856      6.027581e-05  6.327901e-05  6.643659e-05  6.975680e-05
## ASV0909     -1.509997e-04 -1.572383e-04 -1.636909e-04 -1.703609e-04
## ASV0937     -2.826899e-04 -2.955529e-04 -3.089737e-04 -3.229740e-04
## ASV11390    -2.071943e-04 -2.162864e-04 -2.257424e-04 -2.355740e-04
## ASV11966     1.016641e-04  1.063525e-04  1.112490e-04  1.163622e-04
## ASV12990     5.724110e-05  5.994481e-05  6.277480e-05  6.573682e-05
## ASV14797     2.142728e-04  2.238543e-04  2.338361e-04  2.442323e-04
## ASV14904    -2.071897e-04 -2.162814e-04 -2.257370e-04 -2.355681e-04
## ASV15304     5.230783e-05  5.480820e-05  5.742718e-05  6.017020e-05
## ASV16696    -2.071760e-04 -2.162666e-04 -2.257209e-04 -2.355506e-04
## ASV1690      1.056069e-04  1.106613e-04  1.159567e-04  1.215045e-04
## ASV2029      5.708648e-04  5.966449e-04  6.235245e-04  6.515448e-04
## ASV2834      3.024552e-04  3.160743e-04  3.302702e-04  3.450640e-04
## ASV4003      8.914202e-05  9.367580e-05  9.845023e-05  1.034787e-04
## ASV4064      2.085314e-04  2.179086e-04  2.276819e-04  2.378657e-04
## ASV4294      7.659742e-05  8.051007e-05  8.463202e-05  8.897510e-05
## ASV4609     -1.027039e-05 -1.070755e-05 -1.116042e-05 -1.162924e-05
## ASV6283     -2.071737e-04 -2.162642e-04 -2.257185e-04 -2.355481e-04
## ASV6491     -2.071575e-04 -2.162465e-04 -2.256993e-04 -2.355273e-04
## ASV7453      8.240966e-05  8.650915e-05  9.081732e-05  9.534493e-05
## ASV7959      1.439988e-05  1.528803e-05  1.623528e-05  1.724569e-05
## ASV8219      2.071461e-04  2.162341e-04  2.256859e-04  2.355128e-04
## ASV8547     -2.071299e-04 -2.162165e-04 -2.256667e-04 -2.354919e-04
## ASV9319      1.365146e-04  1.427125e-04  1.491774e-04  1.559192e-04
## ASV9382     -2.071197e-04 -2.162055e-04 -2.256547e-04 -2.354788e-04
## ASV11516    -2.071036e-04 -2.161879e-04 -2.256355e-04 -2.354579e-04
## ASV14377    -2.070874e-04 -2.161703e-04 -2.256163e-04 -2.354371e-04
## ASV1867      3.031573e-04  3.171347e-04  3.317349e-04  3.469837e-04
## ASV1895     -7.099376e-05 -7.409940e-05 -7.732885e-05 -8.068604e-05
## ASV3168      1.274011e-04  1.330492e-04  1.389285e-04  1.450466e-04
## ASV4449      2.576244e-04  2.690625e-04  2.809710e-04  2.933660e-04
## ASV6596      1.518194e-04  1.592637e-04  1.670809e-04  1.752901e-04
## ASV7492     -7.770069e-05 -8.086899e-05 -8.414172e-05 -8.752009e-05
## ASV9854     -1.061408e-04 -1.107016e-04 -1.154359e-04 -1.203483e-04
## ASV6296      2.070533e-04  2.161332e-04  2.255761e-04  2.353934e-04
## ASV4201      6.793306e-05  7.149135e-05  7.524631e-05  7.920938e-05
## ASV0552      5.082262e-04  5.317152e-04  5.562546e-04  5.818879e-04
## ASV3671     -4.062297e-05 -4.208254e-05 -4.356992e-05 -4.508302e-05
## ASV3529     -4.734894e-05 -4.921120e-05 -5.112832e-05 -5.310020e-05
## ASV1060      1.296716e-04  1.357739e-04  1.421602e-04  1.488436e-04
## ASV0239     -2.815177e-04 -2.936007e-04 -3.061421e-04 -3.191538e-04
## ASV5711     -2.641963e-04 -2.758488e-04 -2.879733e-04 -3.005853e-04
## ASV4152     -3.470827e-04 -3.625195e-04 -3.785932e-04 -3.953257e-04
## ASV1461      3.110482e-04  3.247595e-04  3.390258e-04  3.538650e-04
## ASV2877      2.519403e-04  2.631782e-04  2.748827e-04  2.870702e-04
## ASV0012      1.888251e-04  1.975272e-04  2.066161e-04  2.161076e-04
## ASV9823      5.921183e-05  6.134806e-05  6.353013e-05  6.575613e-05
## ASV0008      2.062780e-04  2.157309e-04  2.255994e-04  2.359001e-04
## ASV7832     -2.162382e-04 -2.259053e-04 -2.359758e-04 -2.464641e-04
## ASV1915      1.707366e-05  1.802086e-05  1.902393e-05  2.008629e-05
## ASV0055      1.482018e-04  1.549114e-04  1.619084e-04  1.692038e-04
## ASV0032      3.639723e-04  3.804972e-04  3.977360e-04  4.157166e-04
## ASV2977     -2.925800e-04 -3.056001e-04 -3.191581e-04 -3.332723e-04
## ASV0466      2.946452e-04  3.075141e-04  3.208923e-04  3.347956e-04
## ASV3866      3.160479e-04  3.305999e-04  3.457984e-04  3.616699e-04
## ASV0040      4.144775e-04  4.334065e-04  4.531616e-04  4.737752e-04
## ASV0496     -2.414267e-05 -2.564161e-05 -2.724190e-05 -2.895072e-05
## ASV0052      5.060329e-04  5.287042e-04  5.523264e-04  5.769336e-04
## ASV3828     -3.163543e-04 -3.306331e-04 -3.455214e-04 -3.610420e-04
## ASV1930      1.976510e-04  2.067473e-04  2.162464e-04  2.261646e-04
## ASV2126      3.188671e-04  3.333385e-04  3.484343e-04  3.641786e-04
## ASV0793      1.864487e-04  1.950588e-04  2.040544e-04  2.134517e-04
## ASV0299     -1.320674e-04 -1.376389e-04 -1.434116e-04 -1.493898e-04
## ASV0208      3.032856e-04  3.176636e-04  3.327171e-04  3.484772e-04
## ASV0511     -1.590306e-04 -1.657051e-04 -1.726185e-04 -1.797754e-04
## ASV1123     -2.084592e-04 -2.173711e-04 -2.266179e-04 -2.362082e-04
## ASV0099     -1.118731e-04 -1.166396e-04 -1.215835e-04 -1.267092e-04
## ASV0752     -2.491176e-05 -2.626074e-05 -2.768794e-05 -2.919818e-05
## ASV0883      1.439348e-06  1.535258e-06  1.638436e-06  1.749498e-06
## ASV0683      2.689403e-04  2.815999e-04  2.948475e-04  3.087096e-04
## ASV4117     -3.124358e-04 -3.262699e-04 -3.406691e-04 -3.556520e-04
## ASV2172      1.169819e-04  1.222888e-04  1.278250e-04  1.335992e-04
## ASV0330     -2.145467e-04 -2.243914e-04 -2.346723e-04 -2.454074e-04
## ASV0728      1.922269e-04  2.006973e-04  2.095114e-04  2.186805e-04
## ASV0499      4.067551e-04  4.259239e-04  4.459845e-04  4.669775e-04
## ASV0120     -4.425601e-04 -4.625576e-04 -4.834083e-04 -5.051440e-04
## ASV1446      3.703780e-05  3.845944e-05  3.991857e-05  4.141445e-05
## ASV17171    -3.009125e-04 -3.144738e-04 -3.286111e-04 -3.433459e-04
## ASV0533      8.631854e-05  9.041970e-05  9.471401e-05  9.921031e-05
## ASV2495     -1.204684e-04 -1.259664e-04 -1.317045e-04 -1.376922e-04
## ASV5582      1.040578e-04  1.084796e-04  1.130658e-04  1.178203e-04
## ASV1488      1.067200e-04  1.121187e-04  1.177964e-04  1.237675e-04
## ASV0682      2.836894e-04  2.970682e-04  3.110695e-04  3.257213e-04
## ASV0068     -1.577101e-05 -1.670003e-05 -1.768778e-05 -1.873808e-05
## ASV1987     -1.503022e-04 -1.574395e-04 -1.649133e-04 -1.727391e-04
## ASV0035      5.287748e-05  5.486689e-05  5.690401e-05  5.898715e-05
## ASV7192     -1.998722e-04 -2.085671e-04 -2.176027e-04 -2.269888e-04
## ASV0873      2.990099e-05  3.102346e-05  3.217369e-05  3.335100e-05
## ASV4749      1.885677e-05  1.939393e-05  1.992531e-05  2.044809e-05
## ASV2174      1.830421e-04  1.906596e-04  1.985477e-04  2.067122e-04
## ASV1476     -1.643400e-04 -1.717066e-04 -1.793829e-04 -1.873800e-04
## ASV0740     -4.076822e-04 -4.266457e-04 -4.464691e-04 -4.671893e-04
## ASV0170      8.668391e-05  9.064493e-05  9.477981e-05  9.909556e-05
## ASV2466     -3.709769e-04 -3.878887e-04 -4.055375e-04 -4.239524e-04
## ASV1709      2.854936e-04  2.983036e-04  3.116530e-04  3.255616e-04
## ASV6170     -2.422291e-04 -2.524467e-04 -2.630412e-04 -2.740221e-04
## ASV3673      2.900704e-04  3.029216e-04  3.163030e-04  3.302333e-04
## ASV1745      1.784283e-05  1.846048e-05  1.909007e-05  1.973110e-05
## ASV0380     -1.932004e-04 -2.012058e-04 -2.094941e-04 -2.180715e-04
## ASV0426     -5.855639e-05 -6.086043e-05 -6.323251e-05 -6.567253e-05
## ASV0202     -5.853337e-05 -6.044040e-05 -6.236191e-05 -6.429247e-05
## ASV6350     -2.434282e-04 -2.538245e-04 -2.646171e-04 -2.758174e-04
## ASV0713     -1.742479e-04 -1.820628e-04 -1.902078e-04 -1.986951e-04
## ASV1822      3.467453e-05  3.636012e-05  3.812608e-05  3.997589e-05
## ASV4569      2.817148e-04  2.942579e-04  3.073225e-04  3.209274e-04
## ASV0030     -6.326305e-05 -6.632271e-05 -6.953009e-05 -7.289210e-05
## ASV0331      1.176929e-04  1.234312e-04  1.294535e-04  1.357742e-04
## ASV2981      2.868591e-04  3.002010e-04  3.141453e-04  3.287173e-04
## ASV0828     -1.914811e-04 -2.005047e-04 -2.099465e-04 -2.198249e-04
## ASV2440      4.540739e-04  4.752130e-04  4.973110e-04  5.204090e-04
## ASV3006     -1.960625e-04 -2.042072e-04 -2.126417e-04 -2.213727e-04
## ASV3875     -1.960481e-04 -2.041916e-04 -2.126248e-04 -2.213544e-04
## ASV4511      1.143515e-04  1.198046e-04  1.255166e-04  1.314998e-04
## ASV4700     -1.960338e-04 -2.041761e-04 -2.126080e-04 -2.213362e-04
## ASV5804     -1.960194e-04 -2.041605e-04 -2.125911e-04 -2.213179e-04
## ASV6826      2.106304e-04  2.205705e-04  2.309744e-04  2.418631e-04
## ASV7280      1.739679e-04  1.820808e-04  1.905593e-04  1.994183e-04
## ASV7535     -1.960120e-04 -2.041525e-04 -2.125825e-04 -2.213087e-04
## ASV0651     -2.036260e-04 -2.126382e-04 -2.220174e-04 -2.317756e-04
## ASV0913      2.751789e-04  2.880669e-04  3.015485e-04  3.156500e-04
## ASV10832    -1.959983e-04 -2.041376e-04 -2.125665e-04 -2.212913e-04
## ASV1117     -3.897097e-04 -4.071243e-04 -4.252678e-04 -4.441664e-04
## ASV11329     9.666691e-05  1.017709e-04  1.071575e-04  1.128427e-04
## ASV13209    -1.140288e-05 -1.132700e-05 -1.119998e-05 -1.101635e-05
## ASV1345      4.802232e-05  5.032779e-05  5.274046e-05  5.526466e-05
## ASV1719     -1.959760e-04 -2.041136e-04 -2.125405e-04 -2.212633e-04
## ASV1886      2.249752e-04  2.350781e-04  2.456104e-04  2.565887e-04
## ASV2158     -5.304733e-05 -5.491559e-05 -5.682186e-05 -5.876463e-05
## ASV2189      2.410780e-04  2.520829e-04  2.635691e-04  2.755559e-04
## ASV2257      1.775220e-04  1.854075e-04  1.936201e-04  2.021714e-04
## ASV2283      1.959442e-04  2.040790e-04  2.125030e-04  2.212226e-04
## ASV2328      1.959298e-04  2.040634e-04  2.124861e-04  2.212043e-04
## ASV2434     -2.902941e-04 -3.030142e-04 -3.162468e-04 -3.300092e-04
## ASV2648      1.958985e-04  2.040295e-04  2.124493e-04  2.211643e-04
## ASV2698      2.830558e-04  2.960963e-04  3.097185e-04  3.239468e-04
## ASV2775      3.373979e-04  3.520156e-04  3.672038e-04  3.829795e-04
## ASV3171      1.958687e-04  2.039971e-04  2.124141e-04  2.211261e-04
## ASV3227      2.490165e-04  2.596848e-04  2.707583e-04  2.822480e-04
## ASV3397      1.513911e-05  1.588561e-05  1.666650e-05  1.748289e-05
## ASV3444      2.807521e-04  2.929389e-04  3.056069e-04  3.187714e-04
## ASV3556      1.958315e-04  2.039567e-04  2.123702e-04  2.210785e-04
## ASV3606     -1.958171e-04 -2.039411e-04 -2.123533e-04 -2.210603e-04
## ASV4190      2.485207e-04  2.598504e-04  2.716745e-04  2.840128e-04
## ASV4197      2.865767e-04  2.989193e-04  3.117384e-04  3.250478e-04
## ASV4722      2.587635e-04  2.703588e-04  2.824420e-04  2.950308e-04
## ASV4765      6.553114e-05  6.868070e-05  7.197886e-05  7.543206e-05
## ASV4809      1.957818e-04  2.039027e-04  2.123116e-04  2.210150e-04
## ASV4846      1.843591e-04  1.928661e-04  2.017510e-04  2.110292e-04
## ASV4903     -5.054701e-05 -5.219720e-05 -5.386634e-05 -5.555133e-05
## ASV4944     -1.957675e-04 -2.038873e-04 -2.122951e-04 -2.209972e-04
## ASV5151     -7.392655e-05 -7.779785e-05 -8.187866e-05 -8.618028e-05
## ASV5413     -1.957568e-04 -2.038758e-04 -2.122827e-04 -2.209838e-04
## ASV5537     -1.957424e-04 -2.038602e-04 -2.122658e-04 -2.209656e-04
## ASV5688      1.957281e-04  2.038447e-04  2.122490e-04  2.209473e-04
## ASV5752      9.267199e-05  9.707347e-05  1.016784e-04  1.064954e-04
## ASV6122     -1.957174e-04 -2.038331e-04 -2.122365e-04 -2.209338e-04
## ASV6135      1.957030e-04  2.038175e-04  2.122196e-04  2.209156e-04
## ASV6188     -1.956886e-04 -2.038020e-04 -2.122028e-04 -2.208974e-04
## ASV6216      2.891007e-04  3.016805e-04  3.147586e-04  3.283509e-04
## ASV6242      1.956584e-04  2.037691e-04  2.121670e-04  2.208586e-04
## ASV6383      1.956440e-04  2.037535e-04  2.121502e-04  2.208404e-04
## ASV6781      1.956297e-04  2.037380e-04  2.121334e-04  2.208222e-04
## ASV6799     -1.956153e-04 -2.037225e-04 -2.121165e-04 -2.208039e-04
## ASV7374     -1.956010e-04 -2.037069e-04 -2.120997e-04 -2.207857e-04
## ASV7539     -1.955866e-04 -2.036914e-04 -2.120829e-04 -2.207675e-04
## ASV8591     -1.955723e-04 -2.036758e-04 -2.120660e-04 -2.207493e-04
## ASV8637      1.955580e-04  2.036603e-04  2.120492e-04  2.207311e-04
## ASV12796    -1.955436e-04 -2.036448e-04 -2.120324e-04 -2.207128e-04
## ASV1934      2.257804e-04  2.361657e-04  2.470119e-04  2.583377e-04
## ASV22549     1.261620e-05  1.380239e-05  1.508996e-05  1.648657e-05
## ASV29857    -1.955299e-04 -2.036299e-04 -2.120164e-04 -2.206956e-04
## ASV3215      2.745301e-04  2.873000e-04  3.006496e-04  3.146039e-04
## ASV3236     -1.955146e-04 -2.036134e-04 -2.119984e-04 -2.206761e-04
## ASV3954     -1.955003e-04 -2.035978e-04 -2.119816e-04 -2.206579e-04
## ASV4850      1.954860e-04  2.035823e-04  2.119648e-04  2.206397e-04
## ASV5225      1.954716e-04  2.035668e-04  2.119480e-04  2.206215e-04
## ASV5532     -1.954573e-04 -2.035513e-04 -2.119312e-04 -2.206033e-04
## ASV7258      2.400064e-05  2.591882e-05  2.799063e-05  3.022774e-05
## ASV9474     -1.116032e-04 -1.159500e-04 -1.204263e-04 -1.250329e-04
## ASV11857    -1.954380e-04 -2.035305e-04 -2.119088e-04 -2.205793e-04
## ASV1202     -1.954237e-04 -2.035150e-04 -2.118920e-04 -2.205611e-04
## ASV14742     1.387507e-04  1.455960e-04  1.527841e-04  1.603322e-04
## ASV16652     7.046761e-05  7.389382e-05  7.748445e-05  8.124678e-05
## ASV2019      2.861115e-04  2.986775e-04  3.117512e-04  3.253495e-04
## ASV2410     -2.661096e-04 -2.781154e-04 -2.906347e-04 -3.036872e-04
## ASV2718      2.836523e-04  2.970104e-04  3.109860e-04  3.256061e-04
## ASV2738      3.208756e-04  3.347053e-04  3.490683e-04  3.639802e-04
## ASV2876      1.953923e-04  2.034810e-04  2.118553e-04  2.205214e-04
## ASV3177      1.953780e-04  2.034655e-04  2.118385e-04  2.205032e-04
## ASV4367      1.953637e-04  2.034500e-04  2.118217e-04  2.204850e-04
## ASV4635      6.696100e-05  7.068775e-05  7.463161e-05  7.880518e-05
## ASV4896      1.669783e-05  1.832485e-05  2.009661e-05  2.202480e-05
## ASV4907      1.432490e-04  1.503982e-04  1.579109e-04  1.658054e-04
## ASV5230     -1.953630e-04 -2.034496e-04 -2.118216e-04 -2.204854e-04
## ASV6509     -1.953487e-04 -2.034341e-04 -2.118048e-04 -2.204672e-04
## ASV7376     -1.953344e-04 -2.034186e-04 -2.117880e-04 -2.204490e-04
## ASV8163     -1.953201e-04 -2.034031e-04 -2.117712e-04 -2.204309e-04
## ASV8195     -1.953058e-04 -2.033876e-04 -2.117545e-04 -2.204127e-04
## ASV8923      1.192616e-04  1.250634e-04  1.311472e-04  1.375263e-04
## ASV9666     -1.732302e-04 -1.803021e-04 -1.876147e-04 -1.951727e-04
## ASV1482      1.761719e-04  1.842339e-04  1.926476e-04  2.014265e-04
## ASV2726      2.325623e-04  2.434682e-04  2.548738e-04  2.668004e-04
## ASV3281     -1.952902e-04 -2.033708e-04 -2.117365e-04 -2.203934e-04
## ASV4235     -1.952759e-04 -2.033554e-04 -2.117197e-04 -2.203753e-04
## ASV4808      2.881086e-04  3.006064e-04  3.135954e-04  3.270906e-04
## ASV4861     -2.898640e-04 -3.025462e-04 -3.157381e-04 -3.294566e-04
## ASV5276      2.842510e-04  2.965364e-04  3.092998e-04  3.225554e-04
## ASV5837      2.467389e-04  2.581888e-04  2.701572e-04  2.826665e-04
## ASV7098      2.523565e-04  2.640329e-04  2.762353e-04  2.889861e-04
## ASV8451     -1.952106e-04 -2.032843e-04 -2.116425e-04 -2.202913e-04
## ASV8694     -1.951963e-04 -2.032689e-04 -2.116257e-04 -2.202732e-04
## ASV0905     -1.039508e-04 -1.087834e-04 -1.138309e-04 -1.191017e-04
## ASV2900      2.395770e-04  2.497363e-04  2.602761e-04  2.712069e-04
## ASV3963     -1.897980e-04 -1.976218e-04 -2.057188e-04 -2.140950e-04
## ASV0041     -2.116061e-04 -2.214183e-04 -2.316710e-04 -2.423825e-04
## ASV1865      2.162073e-04  2.266773e-04  2.376545e-04  2.491629e-04
## ASV1140      1.728994e-04  1.808832e-04  1.892197e-04  1.979226e-04
## ASV1179      2.552202e-04  2.670409e-04  2.793923e-04  2.922967e-04
## ASV0279      3.593882e-04  3.755004e-04  3.922930e-04  4.097913e-04
## ASV0043     -3.318809e-05 -3.517191e-05 -3.728550e-05 -3.953790e-05
## ASV2097     -2.014669e-04 -2.102539e-04 -2.193924e-04 -2.288943e-04
## ASV0309     -1.001068e-04 -1.044131e-04 -1.088859e-04 -1.135302e-04
## ASV0607      4.393259e-04  4.597729e-04  4.811481e-04  5.034912e-04
## ASV0025     -4.601162e-04 -4.814301e-04 -5.037004e-04 -5.269669e-04
## ASV2284     -7.255774e-05 -7.521991e-05 -7.794432e-05 -8.072927e-05
## ASV0556      7.845888e-05  8.241868e-05  8.658330e-05  9.096337e-05
## ASV5040      1.638345e-04  1.704736e-04  1.773344e-04  1.844204e-04
## ASV2924     -1.751736e-04 -1.823419e-04 -1.897560e-04 -1.974206e-04
## ASV1331      5.573924e-04  5.825387e-04  6.087578e-04  6.360902e-04
## ASV0506     -2.539551e-04 -2.648676e-04 -2.761976e-04 -2.879568e-04
## ASV1514      4.208209e-04  4.400263e-04  4.600686e-04  4.809807e-04
## ASV2144      3.489447e-04  3.644842e-04  3.806677e-04  3.975177e-04
## ASV2265      4.669744e-04  4.881148e-04  5.101621e-04  5.331509e-04
## ASV5156      1.001079e-04  1.040748e-04  1.081644e-04  1.123777e-04
## ASV5534      8.078612e-05  8.380629e-05  8.690238e-05  9.007298e-05
## ASV5747     -1.660556e-05 -1.807761e-05 -1.967336e-05 -2.140229e-05
## ASV6657      2.092056e-04  2.182382e-04  2.276210e-04  2.373643e-04
## ASV0658     -2.382867e-04 -2.485618e-04 -2.592341e-04 -2.703151e-04
## ASV0716      5.763231e-05  6.001355e-05  6.247655e-05  6.502266e-05
## ASV1657      1.013382e-04  1.053280e-04  1.094388e-04  1.136713e-04
## ASV1885     -6.210507e-06 -7.138151e-06 -8.159772e-06 -9.283214e-06
## ASV2333      5.146420e-04  5.376362e-04  5.615918e-04  5.865435e-04
## ASV3375      1.894093e-04  1.974614e-04  2.058154e-04  2.144794e-04
## ASV4317      2.013671e-04  2.105877e-04  2.202159e-04  2.302685e-04
## ASV9599     -1.665929e-05 -1.813588e-05 -1.973652e-05 -2.147073e-05
## ASV0175     -6.888060e-04 -7.194087e-04 -7.512711e-04 -7.844364e-04
## ASV1032      2.041255e-04  2.128071e-04  2.218137e-04  2.311539e-04
## ASV1235      4.478159e-06  4.188623e-06  3.844878e-06  3.441509e-06
## ASV1262      6.077288e-04  6.349315e-04  6.632734e-04  6.927953e-04
## ASV1320      1.509522e-04  1.584300e-04  1.662857e-04  1.745383e-04
## ASV13797     2.256532e-04  2.356072e-04  2.459678e-04  2.567491e-04
## ASV1491      1.154652e-04  1.212454e-04  1.273192e-04  1.337011e-04
## ASV15014    -1.668101e-05 -1.815923e-05 -1.976160e-05 -2.149764e-05
## ASV1510      1.867088e-04  1.957042e-04  2.051308e-04  2.150085e-04
## ASV1551     -7.437099e-05 -7.759422e-05 -8.094278e-05 -8.442027e-05
## ASV1919     -1.011042e-05 -9.830192e-06 -9.475733e-06 -9.039270e-06
## ASV2114      1.105898e-04  1.151954e-04  1.199669e-04  1.249082e-04
## ASV21486    -1.667277e-05 -1.814989e-05 -1.975102e-05 -2.148566e-05
## ASV2448      3.085923e-04  3.220250e-04  3.359874e-04  3.504957e-04
## ASV2589      1.475119e-04  1.537805e-04  1.602839e-04  1.670285e-04
## ASV2608      2.488452e-04  2.599139e-04  2.714421e-04  2.834464e-04
## ASV2786      2.018104e-04  2.109906e-04  2.205726e-04  2.305730e-04
## ASV2827      2.577667e-04  2.691193e-04  2.809311e-04  2.932172e-04
## ASV2872      2.098814e-04  2.187623e-04  2.279704e-04  2.375136e-04
## ASV3125      2.509926e-04  2.618359e-04  2.731011e-04  2.848007e-04
## ASV3247      2.718394e-04  2.835733e-04  2.957613e-04  3.084163e-04
## ASV3451     -1.675141e-05 -1.823543e-05 -1.984402e-05 -2.158674e-05
## ASV3465     -3.491614e-05 -3.727010e-05 -3.979102e-05 -4.249059e-05
## ASV3809      1.583413e-04  1.650613e-04  1.720319e-04  1.792595e-04
## ASV4006      3.370847e-04  3.515335e-04  3.665306e-04  3.820907e-04
## ASV4046      2.422129e-04  2.526729e-04  2.635393e-04  2.748242e-04
## ASV4938     -1.832866e-05 -1.988668e-05 -2.157266e-05 -2.339629e-05
## ASV5435     -1.677474e-05 -1.826044e-05 -1.987081e-05 -2.161539e-05
## ASV5605      9.691827e-05  1.005995e-04  1.043784e-04  1.082536e-04
## ASV5635     -1.677784e-05 -1.826362e-05 -1.987406e-05 -2.161868e-05
## ASV5743      3.056751e-04  3.190904e-04  3.330464e-04  3.475610e-04
## ASV6627     -1.679125e-05 -1.827811e-05 -1.988971e-05 -2.163559e-05
## ASV6785     -1.678870e-05 -1.827522e-05 -1.988643e-05 -2.163186e-05
## ASV7368      3.370277e-04  3.524543e-04  3.685613e-04  3.853766e-04
## ASV9118      9.149556e-05  9.501391e-05  9.863056e-05  1.023450e-04
## ASV9135      7.140971e-05  7.394067e-05  7.652089e-05  7.914749e-05
## ASV9435      1.590411e-04  1.654785e-04  1.721262e-04  1.789868e-04
## ASV9671     -1.681291e-05 -1.830132e-05 -1.991455e-05 -2.166214e-05
## ASV0387     -3.386890e-04 -3.533531e-04 -3.685885e-04 -3.844121e-04
## ASV0454     -3.369655e-04 -3.517122e-04 -3.670472e-04 -3.829888e-04
## ASV0751     -2.209678e-04 -2.304707e-04 -2.403382e-04 -2.505807e-04
## ASV1081      8.958495e-05  9.362311e-05  9.783173e-05  1.022169e-04
## ASV1332      1.843787e-04  1.925826e-04  2.011254e-04  2.100190e-04
## ASV2659      2.935570e-04  3.069582e-04  3.209415e-04  3.355293e-04
## ASV2979      3.047752e-04  3.178429e-04  3.314076e-04  3.454830e-04
## ASV4184      1.231845e-04  1.279324e-04  1.328130e-04  1.378256e-04
## ASV6198      1.073440e-04  1.118952e-04  1.166167e-04  1.215131e-04
## ASV7454      1.991183e-04  2.077104e-04  2.166348e-04  2.259009e-04
## ASV8198      7.987304e-05  8.274239e-05  8.567159e-05  8.865783e-05
## ASV0855      4.461242e-04  4.664591e-04  4.876801e-04  5.098223e-04
## ASV10092     1.885494e-04  1.966947e-04  2.051576e-04  2.139477e-04
## ASV1532      2.431133e-04  2.544657e-04  2.663366e-04  2.787485e-04
## ASV2553      5.874711e-04  6.139827e-04  6.416252e-04  6.704410e-04
## ASV2741      2.361855e-04  2.472656e-04  2.588531e-04  2.709696e-04
## ASV4095      1.280704e-04  1.343874e-04  1.410180e-04  1.479770e-04
## ASV5295      1.732701e-04  1.804184e-04  1.878143e-04  1.954623e-04
## ASV5787     -1.686916e-05 -1.836204e-05 -1.998003e-05 -2.173269e-05
## ASV9455      2.291084e-04  2.390619e-04  2.494082e-04  2.601595e-04
## ASV10879     2.390803e-04  2.497700e-04  2.609095e-04  2.725155e-04
## ASV3997      1.667878e-04  1.747847e-04  1.831618e-04  1.919365e-04
## ASV6760      4.713360e-05  4.848848e-05  4.983595e-05  5.117052e-05
## ASV6990      1.729259e-04  1.803198e-04  1.879956e-04  1.959612e-04
## ASV9560      1.070299e-04  1.113833e-04  1.158832e-04  1.205320e-04
## ASV0220      9.463765e-05  9.883227e-05  1.031977e-04  1.077393e-04
## ASV2518      2.305896e-04  2.410821e-04  2.520301e-04  2.634514e-04
## ASV3615      3.629653e-04  3.791510e-04  3.960110e-04  4.135693e-04
## ASV0075      7.865112e-05  8.179735e-05  8.504122e-05  8.838313e-05
## ASV8070      4.381730e-05  4.510153e-05  4.638215e-05  4.765438e-05
## ASV1658      1.718255e-04  1.792527e-04  1.869690e-04  1.949833e-04
## ASV0773      2.775403e-04  2.895022e-04  3.019250e-04  3.148218e-04
## ASV0799      8.902972e-06  9.291373e-06  9.694972e-06  1.011420e-05
## ASV1839     -5.471997e-05 -5.678377e-05 -5.889772e-05 -6.106016e-05
## ASV0265      2.674823e-04  2.801859e-04  2.934862e-04  3.074101e-04
## ASV3741      1.078185e-04  1.126455e-04  1.176747e-04  1.229135e-04
## ASV0847      3.748688e-04  3.917060e-04  4.092531e-04  4.275357e-04
## ASV1026      4.003680e-04  4.182041e-04  4.367788e-04  4.561177e-04
## ASV1222     -1.267177e-04 -1.318474e-04 -1.371467e-04 -1.426182e-04
## ASV0729      5.469077e-05  5.709800e-05  5.960209e-05  6.220611e-05
## ASV0143     -3.042335e-04 -3.173106e-04 -3.308875e-04 -3.449781e-04
## ASV1328      7.800525e-05  8.127247e-05  8.465757e-05  8.816324e-05
## ASV9078     -7.902089e-05 -8.339847e-05 -8.803135e-05 -9.293461e-05
## ASV0027     -4.382509e-04 -4.584465e-04 -4.795386e-04 -5.015638e-04
## ASV0546     -1.914154e-04 -1.996488e-04 -2.081983e-04 -2.170730e-04
## ASV1136      4.881987e-04  5.100183e-04  5.327514e-04  5.564313e-04
## ASV3081      2.331209e-04  2.437132e-04  2.547663e-04  2.662988e-04
## ASV0531      1.034588e-04  1.083743e-04  1.135193e-04  1.189036e-04
## ASV2525      1.336030e-04  1.393843e-04  1.453911e-04  1.516300e-04
## ASV1083     -5.061478e-05 -5.252803e-05 -5.449273e-05 -5.650858e-05
## ASV0424      8.699641e-05  9.098569e-05  9.515181e-05  9.950214e-05
## ASV0644      1.161799e-05  1.263697e-05  1.374007e-05  1.493353e-05
## ASV6007     -1.700890e-05 -1.851639e-05 -2.015055e-05 -2.192109e-05
## ASV0564      1.202804e-04  1.261148e-04  1.322321e-04  1.386455e-04
## ASV1938      1.296884e-04  1.350813e-04  1.406660e-04  1.464468e-04
## ASV6516     -2.978332e-04 -3.112042e-04 -3.251387e-04 -3.396570e-04
## ASV0503     -3.490962e-04 -3.640512e-04 -3.795729e-04 -3.956768e-04
## ASV6913     -3.468678e-04 -3.617193e-04 -3.771358e-04 -3.931330e-04
## ASV0164     -2.769508e-04 -2.899555e-04 -3.035611e-04 -3.177943e-04
## ASV1576      3.310182e-04  3.458890e-04  3.613901e-04  3.775452e-04
## ASV1725      1.606185e-04  1.683849e-04  1.765258e-04  1.850588e-04
## ASV4501      1.400248e-04  1.457865e-04  1.517465e-04  1.579085e-04
## ASV10678    -2.905474e-04 -3.034597e-04 -3.169039e-04 -3.308985e-04
## ASV0944      2.421448e-04  2.535097e-04  2.653981e-04  2.778333e-04
## ASV2292      3.771339e-04  3.938847e-04  4.113262e-04  4.294822e-04
## ASV1090      2.471544e-04  2.583626e-04  2.700548e-04  2.822499e-04
## ASV9117     -1.202572e-04 -1.251499e-04 -1.302072e-04 -1.354317e-04
## ASV0285     -1.460038e-04 -1.532398e-04 -1.608400e-04 -1.688226e-04
## ASV0463     -2.409857e-04 -2.514684e-04 -2.623631e-04 -2.736823e-04
## ASV3199      2.077784e-04  2.166544e-04  2.258665e-04  2.354239e-04
## ASV0150     -8.525382e-05 -8.945882e-05 -9.387385e-05 -9.850931e-05
## ASV6583     -1.233459e-04 -1.285431e-04 -1.339331e-04 -1.395210e-04
## ASV0392      1.977553e-04  2.067975e-04  2.162364e-04  2.260880e-04
## ASV14007    -2.390327e-04 -2.496789e-04 -2.607661e-04 -2.723096e-04
## ASV0177     -1.317441e-04 -1.373685e-04 -1.432052e-04 -1.492599e-04
## ASV6448     -1.026734e-04 -1.080795e-04 -1.137813e-04 -1.197949e-04
## ASV5399     -4.267590e-05 -4.534620e-05 -4.819319e-05 -5.122852e-05
## ASV0277     -4.931047e-05 -5.160912e-05 -5.401209e-05 -5.652380e-05
## ASV2599      8.139679e-05  8.416755e-05  8.698011e-05  8.982990e-05
## ASV13465    -6.514746e-05 -6.720748e-05 -6.928049e-05 -7.136090e-05
## ASV2412      1.238009e-04  1.294505e-04  1.353463e-04  1.414979e-04
## ASV0423      2.447836e-04  2.565667e-04  2.689205e-04  2.818728e-04
## ASV5187      1.508292e-04  1.569861e-04  1.633520e-04  1.699306e-04
## ASV0701     -5.695093e-04 -5.953242e-04 -6.222479e-04 -6.503224e-04
## ASV4248      1.364492e-04  1.430303e-04  1.499267e-04  1.571529e-04
## ASV0519      2.397094e-04  2.509046e-04  2.626091e-04  2.748446e-04
## ASV0764      4.139332e-05  4.360714e-05  4.594549e-05  4.841559e-05
## ASV5385     -2.997081e-04 -3.134019e-04 -3.276940e-04 -3.426081e-04
## ASV3021     -1.679823e-04 -1.746781e-04 -1.815853e-04 -1.887062e-04
## ASV4119     -9.353163e-05 -9.715603e-05 -1.008847e-04 -1.047176e-04
## ASV2534      4.874353e-05  5.085138e-05  5.304241e-05  5.531936e-05
## ASV1061      2.313042e-04  2.427897e-04  2.548603e-04  2.675465e-04
## ASV0670      3.195229e-04  3.341284e-04  3.493729e-04  3.652814e-04
## ASV1384      1.392781e-04  1.461630e-04  1.533930e-04  1.609851e-04
## ASV1981      2.978021e-04  3.115629e-04  3.259374e-04  3.409506e-04
## ASV9632     -9.739320e-05 -1.010346e-04 -1.047688e-04 -1.085944e-04
## ASV4564      7.344094e-05  7.687165e-05  8.045854e-05  8.420828e-05
## ASV5289     -6.634349e-05 -6.934378e-05 -7.247228e-05 -7.573378e-05
## ASV0516      6.055030e-04  6.330907e-04  6.618764e-04  6.919067e-04
## ASV1463     -2.176625e-04 -2.271892e-04 -2.370946e-04 -2.473905e-04
## ASV0969      1.010814e-04  1.054198e-04  1.099224e-04  1.145935e-04
## ASV1113     -2.820740e-04 -2.949187e-04 -3.083218e-04 -3.223054e-04
## ASV1234     -1.115916e-05 -1.232602e-05 -1.360257e-05 -1.499821e-05
## ASV3814      4.150791e-05  4.257397e-05  4.361772e-05  4.463295e-05
## ASV1000      2.878089e-04  3.005578e-04  3.138280e-04  3.276372e-04
## ASV0079     -2.616476e-05 -2.777180e-05 -2.948594e-05 -3.131465e-05
## ASV0145      9.733218e-05  1.013829e-04  1.055779e-04  1.099201e-04
## ASV0457     -3.622429e-04 -3.781451e-04 -3.946859e-04 -4.118856e-04
## ASV1485      1.185792e-04  1.241549e-04  1.299895e-04  1.360945e-04
## ASV0535     -7.980585e-05 -8.328450e-05 -8.690330e-05 -9.066718e-05
## ASV0259     -2.373989e-04 -2.480161e-04 -2.590750e-04 -2.705908e-04
## ASV0570      1.811377e-05  1.931595e-05  2.060289e-05  2.198059e-05
## ASV0906      3.085327e-04  3.222113e-04  3.364509e-04  3.512705e-04
## ASV1748     -1.832676e-04 -1.923121e-04 -2.018083e-04 -2.117785e-04
## ASV5520     -1.089768e-04 -1.147261e-04 -1.207919e-04 -1.271919e-04
## ASV2288     -3.532070e-04 -3.684983e-04 -3.843842e-04 -4.008820e-04
## ASV1887     -6.798525e-05 -7.170385e-05 -7.563502e-05 -7.979092e-05
## ASV0374     -1.120071e-04 -1.167780e-04 -1.217273e-04 -1.268598e-04
## ASV0823      3.481289e-04  3.633543e-04  3.791874e-04  3.956475e-04
## ASV0717      1.756203e-04  1.837071e-04  1.921533e-04  2.009735e-04
## ASV0431      1.207225e-04  1.259676e-04  1.314179e-04  1.370793e-04
## ASV1030      5.087301e-04  5.325576e-04  5.574775e-04  5.835375e-04
## ASV1082     -7.422587e-05 -7.760865e-05 -8.113822e-05 -8.482026e-05
## ASV2684      4.771942e-05  5.045878e-05  5.336324e-05  5.644270e-05
## ASV0051      4.517865e-04  4.726910e-04  4.945344e-04  5.173564e-04
## ASV0513      1.912284e-05  2.009569e-05  2.112007e-05  2.219883e-05
## ASV0581      5.726995e-04  5.988690e-04  6.261821e-04  6.546842e-04
## ASV7282      1.011060e-04  1.063042e-04  1.117822e-04  1.175560e-04
## ASV3009     -3.138905e-04 -3.281596e-04 -3.430457e-04 -3.585726e-04
## ASV2106     -1.587969e-04 -1.655471e-04 -1.725499e-04 -1.798118e-04
## ASV1012      1.011051e-04  1.060658e-04  1.112725e-04  1.167373e-04
## ASV0921     -6.554603e-06 -6.722224e-06 -6.885323e-06 -7.042676e-06
## ASV0010     -4.482562e-04 -4.690582e-04 -4.907972e-04 -5.135126e-04
## ASV1178      9.476655e-06  1.007879e-05  1.072048e-05  1.140418e-05
## ASV2848     -2.403169e-04 -2.509159e-04 -2.619472e-04 -2.734258e-04
## ASV0586      6.497186e-04  6.795117e-04  7.106167e-04  7.430864e-04
## ASV4225      1.965897e-05  2.089842e-05  2.221672e-05  2.361839e-05
## ASV2156     -2.707879e-04 -2.831727e-04 -2.961006e-04 -3.095932e-04
## ASV9778     -1.705246e-04 -1.781541e-04 -1.861022e-04 -1.943805e-04
## ASV0493     -3.774351e-04 -3.942035e-04 -4.116644e-04 -4.298419e-04
## ASV3770      6.904283e-05  7.190357e-05  7.486691e-05  7.793544e-05
## ASV0470      4.611258e-04  4.820933e-04  5.039692e-04  5.267888e-04
## ASV0262     -1.930338e-04 -2.025375e-04 -2.125157e-04 -2.229923e-04
## ASV0998      2.829650e-04  2.959807e-04  3.095737e-04  3.237679e-04
## ASV7708     -7.707965e-05 -8.045711e-05 -8.396930e-05 -8.762044e-05
## ASV0453     -9.686506e-06 -1.009342e-05 -1.051671e-05 -1.095714e-05
## ASV0044      5.811575e-04  6.076920e-04  6.353860e-04  6.642856e-04
## ASV5490      9.091268e-05  9.485818e-05  9.895666e-05  1.032123e-04
## ASV2638      2.501649e-05  2.630180e-05  2.765319e-05  2.907374e-05
## ASV0829     -5.151590e-05 -5.347561e-05 -5.548898e-05 -5.755576e-05
## ASV0601      1.072808e-04  1.124350e-04  1.178379e-04  1.235013e-04
## ASV0234      2.521626e-04  2.635518e-04  2.754271e-04  2.878065e-04
## ASV0133      3.335843e-04  3.488727e-04  3.648344e-04  3.814968e-04
## ASV0323      3.542031e-04  3.707988e-04  3.881591e-04  4.063181e-04
## ASV0854     -2.664761e-05 -2.765896e-05 -2.869560e-05 -2.975680e-05
## ASV0110      4.479275e-04  4.686815e-04  4.903695e-04  5.130308e-04
## ASV0816      2.420227e-05  2.524115e-05  2.632033e-05  2.744110e-05
## ASV1031     -6.999291e-05 -7.302749e-05 -7.618306e-05 -7.946382e-05
## ASV0144     -1.823388e-04 -1.905642e-04 -1.991400e-04 -2.080792e-04
## ASV0020     -8.409098e-05 -8.847360e-05 -9.309841e-05 -9.797974e-05
## ASV0962     -1.492790e-04 -1.560484e-04 -1.631087e-04 -1.704711e-04
## ASV0794      2.953915e-04  3.095360e-04  3.243547e-04  3.398787e-04
## ASV7117     -1.522664e-04 -1.592611e-04 -1.665662e-04 -1.741946e-04
## ASV1008     -1.088523e-04 -1.140570e-04 -1.195103e-04 -1.252243e-04
## ASV0096      4.824937e-04  5.048663e-04  5.282472e-04  5.526792e-04
## ASV0128     -2.893292e-04 -3.031841e-04 -3.177038e-04 -3.329202e-04
## ASV5232      2.187935e-04  2.289761e-04  2.396190e-04  2.507416e-04
## ASV0031      1.355034e-05  1.388488e-05  1.420786e-05  1.451644e-05
## ASV1744     -3.332269e-05 -3.494423e-05 -3.664839e-05 -3.843984e-05
## ASV0289      2.685413e-04  2.809106e-04  2.938316e-04  3.073275e-04
## ASV7413     -6.101324e-05 -6.448216e-05 -6.815958e-05 -7.205816e-05
## ASV0822     -3.228597e-04 -3.371072e-04 -3.519338e-04 -3.673588e-04
## ASV8111     -2.722440e-04 -2.836871e-04 -2.955473e-04 -3.078347e-04
## ASV0687      2.018853e-04  2.113883e-04  2.213301e-04  2.317300e-04
## ASV0112      6.263673e-05  6.470312e-05  6.678617e-05  6.887972e-05
## ASV0987      1.627309e-04  1.704054e-04  1.784372e-04  1.868425e-04
## ASV5332     -8.878591e-05 -9.239165e-05 -9.612027e-05 -9.997432e-05
## ASV1129     -2.124931e-04 -2.223107e-04 -2.325692e-04 -2.432874e-04
## ASV1274     -6.971031e-05 -7.293594e-05 -7.630615e-05 -7.982698e-05
## ASV0119      3.930724e-04  4.112707e-04  4.302867e-04  4.501546e-04
## ASV0890      9.964891e-05  1.044107e-04  1.093993e-04  1.146252e-04
## ASV0848      5.634973e-04  5.893329e-04  6.163059e-04  6.444619e-04
## ASV5944     -2.933686e-04 -3.060254e-04 -3.191711e-04 -3.328197e-04
## ASV19741    -2.949629e-04 -3.083927e-04 -3.224065e-04 -3.370272e-04
## ASV0504     -3.376823e-04 -3.526656e-04 -3.682659e-04 -3.845049e-04
## ASV2146     -2.216333e-04 -2.315520e-04 -2.418907e-04 -2.526656e-04
## ASV0089     -1.855213e-04 -1.943242e-04 -2.035406e-04 -2.131893e-04
## ASV2301     -1.962317e-04 -2.053331e-04 -2.148447e-04 -2.247840e-04
## ASV2982      5.905712e-05  6.198665e-05  6.505959e-05  6.828227e-05
## ASV0891     -2.481851e-04 -2.595349e-04 -2.713823e-04 -2.837471e-04
## ASV0093      4.029629e-04  4.213758e-04  4.405946e-04  4.606514e-04
## ASV0042      1.905054e-04  1.989971e-04  2.078411e-04  2.170500e-04
## ASV0980      2.669341e-04  2.788446e-04  2.912502e-04  3.041684e-04
## ASV0069     -6.779994e-05 -7.115731e-05 -7.468555e-05 -7.839365e-05
## ASV1364     -4.781373e-05 -5.004529e-05 -5.237911e-05 -5.481974e-05
## ASV0524     -7.816899e-05 -8.199595e-05 -8.601375e-05 -9.023212e-05
## ASV0435      5.330811e-04  5.576270e-04  5.832637e-04  6.100362e-04
## ASV0517     -2.163915e-04 -2.262727e-04 -2.365850e-04 -2.473456e-04
## ASV3167     -9.355059e-05 -9.798096e-05 -1.026176e-04 -1.074696e-04
## ASV4280     -3.942941e-05 -4.143225e-05 -4.354216e-05 -4.576527e-05
## ASV1158      1.304129e-04  1.367608e-04  1.434172e-04  1.503965e-04
## ASV2214      1.009516e-04  1.056069e-04  1.104737e-04  1.155615e-04
## ASV0544     -1.197701e-04 -1.253145e-04 -1.311078e-04 -1.371603e-04
## ASV5326     -2.168522e-05 -2.263761e-05 -2.362849e-05 -2.465914e-05
## ASV3765     -3.104390e-04 -3.242533e-04 -3.386376e-04 -3.536116e-04
## ASV4646     -8.117708e-06 -9.026301e-06 -1.001967e-05 -1.110471e-05
## ASV0090      3.091015e-05  3.205492e-05  3.322576e-05  3.442159e-05
## ASV3680      2.925803e-04  3.052798e-04  3.184762e-04  3.321842e-04
## ASV0111      4.846846e-05  5.044778e-05  5.249256e-05  5.460355e-05
## ASV0768      1.824395e-04  1.908729e-04  1.996846e-04  2.088906e-04
## ASV4862     -1.061223e-05 -1.101987e-05 -1.143852e-05 -1.186805e-05
## ASV1742     -2.402190e-04 -2.507108e-04 -2.616213e-04 -2.729641e-04
## ASV3701     -4.232646e-05 -4.432785e-05 -4.642381e-05 -4.861885e-05
## ASV2386     -1.449230e-04 -1.514734e-04 -1.583031e-04 -1.654225e-04
## ASV0375     -3.383948e-04 -3.533516e-04 -3.689193e-04 -3.851186e-04
## ASV2796      9.030145e-05  9.424821e-05  9.835276e-05  1.026202e-04
## ASV1369      2.338628e-04  2.442348e-04  2.550352e-04  2.662791e-04
## ASV10272    -2.119592e-04 -2.214845e-04 -2.314116e-04 -2.417550e-04
## ASV10354    -2.119423e-04 -2.214660e-04 -2.313914e-04 -2.417330e-04
## ASV1067     -1.817565e-05 -1.908772e-05 -2.004718e-05 -2.105659e-05
## ASV1900      4.445308e-04  4.650215e-04  4.864245e-04  5.087774e-04
## ASV4079     -7.630415e-05 -7.991807e-05 -8.370075e-05 -8.765970e-05
## ASV4149      2.979896e-04  3.109554e-04  3.244310e-04  3.384316e-04
## ASV5140     -2.119252e-04 -2.214474e-04 -2.313711e-04 -2.417107e-04
## ASV10782    -9.525800e-06 -9.809395e-06 -1.009167e-05 -1.037137e-05
## ASV4273     -4.853930e-05 -5.054741e-05 -5.262404e-05 -5.477015e-05
## ASV8121      2.047454e-04  2.141858e-04  2.240477e-04  2.343489e-04
## ASV8438     -2.119103e-04 -2.214312e-04 -2.313534e-04 -2.416915e-04
## ASV9390     -2.118934e-04 -2.214127e-04 -2.313332e-04 -2.416695e-04
## ASV1340      2.940951e-04  3.077229e-04  3.219636e-04  3.368427e-04
## ASV2650     -3.145371e-04 -3.284861e-04 -3.430069e-04 -3.581185e-04
## ASV4674      1.613173e-04  1.686836e-04  1.763715e-04  1.843936e-04
## ASV10492    -1.394615e-05 -1.463915e-05 -1.536767e-05 -1.613362e-05
## ASV11430    -2.118682e-04 -2.213852e-04 -2.313033e-04 -2.416369e-04
## ASV12135    -2.118512e-04 -2.213667e-04 -2.312831e-04 -2.416149e-04
## ASV14970    -2.118343e-04 -2.213482e-04 -2.312629e-04 -2.415928e-04
## ASV1954      2.419177e-04  2.529639e-04  2.644916e-04  2.765199e-04
## ASV2613      3.779202e-04  3.950784e-04  4.129771e-04  4.316449e-04
## ASV2757      1.491455e-04  1.556288e-04  1.623665e-04  1.693663e-04
## ASV2909     -2.215320e-04 -2.316978e-04 -2.423116e-04 -2.533916e-04
## ASV2954     -4.248567e-05 -4.426914e-05 -4.611594e-05 -4.802723e-05
## ASV2969      2.091422e-04  2.189185e-04  2.291423e-04  2.398331e-04
## ASV3410      4.514280e-05  4.744360e-05  4.986703e-05  5.241998e-05
## ASV3575      1.111376e-04  1.162435e-04  1.215764e-04  1.271457e-04
## ASV4275      2.403563e-04  2.508732e-04  2.618084e-04  2.731747e-04
## ASV4652      4.257514e-05  4.474825e-05  4.703659e-05  4.944646e-05
## ASV4761      2.401430e-04  2.506652e-04  2.616064e-04  2.729796e-04
## ASV6003      1.867243e-04  1.956421e-04  2.049859e-04  2.147758e-04
## ASV6110     -2.118710e-04 -2.213884e-04 -2.313069e-04 -2.416409e-04
## ASV7427      1.387102e-04  1.450478e-04  1.516627e-04  1.585659e-04
## ASV8092     -2.118601e-04 -2.213765e-04 -2.312939e-04 -2.416269e-04
## ASV8169     -2.118432e-04 -2.213580e-04 -2.312738e-04 -2.416048e-04
## ASV9693      9.277024e-05  9.703519e-05  1.014889e-04  1.061391e-04
## ASV10913     1.024880e-04  1.073775e-04  1.124995e-04  1.178649e-04
## ASV1979     -3.450302e-05 -3.599977e-05 -3.755497e-05 -3.917036e-05
## ASV3772      2.627531e-04  2.745363e-04  2.868157e-04  2.996092e-04
## ASV0113      4.937229e-05  5.139594e-05  5.348640e-05  5.564430e-05
## ASV1800     -2.266725e-05 -2.376550e-05 -2.491624e-05 -2.612181e-05
## ASV2335     -2.659000e-04 -2.770873e-04 -2.886832e-04 -3.006976e-04
## ASV0692      9.148860e-05  9.576472e-05  1.002361e-04  1.049111e-04
## ASV1120      1.152667e-04  1.205145e-04  1.259900e-04  1.317018e-04
## ASV1434     -6.114278e-04 -6.392887e-04 -6.683618e-04 -6.986945e-04
## ASV0076     -7.122478e-05 -7.473565e-05 -7.842385e-05 -8.229859e-05
## ASV0361      4.634303e-04  4.848714e-04  5.072743e-04  5.306794e-04
## ASV2231     -1.563942e-04 -1.641756e-04 -1.723554e-04 -1.809545e-04
## ASV2018     -1.310835e-05 -1.404925e-05 -1.506351e-05 -1.615709e-05
## ASV1529      3.847518e-04  4.026792e-04  4.214227e-04  4.410177e-04
## ASV0841     -1.919253e-05 -1.993278e-05 -2.069298e-05 -2.147281e-05
## ASV2556     -2.308958e-04 -2.413123e-04 -2.521718e-04 -2.634909e-04
## ASV2777      2.912301e-04  3.038581e-04  3.169788e-04  3.306066e-04
## ASV0355      2.402323e-04  2.513970e-04  2.630679e-04  2.752669e-04
## ASV5169     -3.281573e-04 -3.430090e-04 -3.584968e-04 -3.746447e-04
## ASV3091      1.613347e-04  1.689955e-04  1.770179e-04  1.854188e-04
## ASV2435      2.315254e-04  2.419143e-04  2.527393e-04  2.640161e-04
## ASV6822     -1.495108e-04 -1.562301e-04 -1.632327e-04 -1.705289e-04
## ASV12605    -3.582967e-04 -3.745438e-04 -3.914899e-04 -4.091617e-04
## ASV0286     -2.396834e-04 -2.505745e-04 -2.619386e-04 -2.737946e-04
## ASV0074     -1.528271e-05 -1.654049e-05 -1.790427e-05 -1.938285e-05
## ASV2485     -9.503865e-06 -9.717723e-06 -9.922535e-06 -1.011652e-05
## ASV1233     -4.583325e-04 -4.793717e-04 -5.013413e-04 -5.242794e-04
## ASV0356     -2.186400e-04 -2.284412e-04 -2.386557e-04 -2.492985e-04
## ASV2918     -2.639547e-04 -2.752582e-04 -2.869907e-04 -2.991638e-04
## ASV1427     -4.731059e-07 -6.328769e-07 -8.124440e-07 -1.013773e-06
## ASV1409      2.689510e-04  2.816490e-04  2.949409e-04  3.088538e-04
## ASV0770      8.187379e-05  8.518200e-05  8.859356e-05  9.210859e-05
## ASV1403     -3.216491e-04 -3.362546e-04 -3.514907e-04 -3.673817e-04
## ASV0314     -1.746592e-04 -1.826569e-04 -1.910051e-04 -1.997180e-04
## ASV0187      3.238396e-06  3.099425e-06  2.930160e-06  2.727493e-06
## ASV0313     -2.331715e-04 -2.435384e-04 -2.543329e-04 -2.655698e-04
## ASV1087      4.077835e-04  4.265707e-04  4.461942e-04  4.666887e-04
## ASV1970      2.137785e-05  2.220839e-05  2.306187e-05  2.393801e-05
## ASV0754      3.281411e-04  3.432584e-04  3.590489e-04  3.755405e-04
## ASV3775     -2.238817e-04 -2.343356e-04 -2.452674e-04 -2.566980e-04
## ASV0132      9.135582e-05  9.536539e-05  9.953455e-05  1.038681e-04
## ASV2329     -6.481532e-05 -6.836504e-05 -7.211964e-05 -7.609117e-05
## ASV0561      2.796433e-04  2.921096e-04  3.050927e-04  3.186103e-04
## ASV0130     -3.429945e-04 -3.587266e-04 -3.751513e-04 -3.922965e-04
## ASV0226      3.890628e-04  4.068595e-04  4.254360e-04  4.448232e-04
## ASV12648    -2.758481e-04 -2.882813e-04 -3.012460e-04 -3.147626e-04
## ASV0204      3.878284e-04  4.055616e-04  4.240711e-04  4.433876e-04
## ASV0767      6.401753e-05  6.651039e-05  6.907213e-05  7.170177e-05
## ASV0335     -2.125420e-04 -2.223436e-04 -2.325815e-04 -2.432736e-04
## ASV5901     -6.300577e-05 -6.560606e-05 -6.829675e-05 -7.107960e-05
## ASV0596     -8.124228e-05 -8.453961e-05 -8.794355e-05 -9.145497e-05
## ASV9271      8.013834e-05  8.430939e-05  8.870579e-05  9.333983e-05
## ASV0904      3.420538e-04  3.578321e-04  3.743143e-04  3.915295e-04
## ASV15270    -8.959143e-05 -9.398043e-05 -9.858321e-05 -1.034096e-04
## ASV0990     -9.913349e-05 -1.038735e-04 -1.088402e-04 -1.140444e-04
## ASV0155     -2.056383e-04 -2.149533e-04 -2.246684e-04 -2.347988e-04
## ASV0086     -8.371201e-07 -7.854451e-07 -7.233996e-07 -6.498595e-07
## ASV2581     -1.219031e-05 -1.246344e-05 -1.272153e-05 -1.296142e-05
## ASV1579     -2.435453e-04 -2.550837e-04 -2.671639e-04 -2.798108e-04
## ASV7730     -1.047150e-05 -1.139126e-05 -1.238714e-05 -1.346481e-05
## ASV0897      9.959441e-05  1.041983e-04  1.090083e-04  1.140330e-04
## ASV1975      4.675894e-04  4.889023e-04  5.111434e-04  5.343493e-04
## ASV0759     -1.108329e-05 -1.149587e-05 -1.191828e-05 -1.235023e-05
## ASV3082     -2.839776e-04 -2.970268e-04 -3.106538e-04 -3.248820e-04
## ASV3195     -4.960637e-04 -5.191826e-04 -5.433552e-04 -5.686276e-04
## ASV0427      2.604027e-04  2.725776e-04  2.853106e-04  2.986260e-04
## ASV2674      5.362090e-05  5.593577e-05  5.833792e-05  6.082935e-05
## ASV1500      8.065648e-05  8.432860e-05  8.816075e-05  9.215929e-05
## ASV0102     -2.981046e-04 -3.121283e-04 -3.268028e-04 -3.421573e-04
## ASV1217     -7.471467e-05 -7.793297e-05 -8.127348e-05 -8.473930e-05
## ASV4998     -3.122944e-05 -3.265445e-05 -3.414131e-05 -3.569240e-05
## ASV2890      4.240303e-04  4.431021e-04  4.629812e-04  4.836974e-04
## ASV0672     -1.845288e-04 -1.930420e-04 -2.019355e-04 -2.112251e-04
## ASV6960     -1.675698e-04 -1.756885e-04 -1.841997e-04 -1.931215e-04
## ASV0821      2.751171e-04  2.873366e-04  3.000603e-04  3.133058e-04
## ASV1995     -2.634285e-04 -2.755696e-04 -2.882511e-04 -3.014952e-04
## ASV0211     -1.488412e-04 -1.560818e-04 -1.636777e-04 -1.716463e-04
## ASV0364      1.538906e-04  1.610243e-04  1.684798e-04  1.762709e-04
## ASV3616      3.287262e-04  3.430085e-04  3.578509e-04  3.732700e-04
## ASV1996      3.724293e-04  3.893823e-04  4.070732e-04  4.255313e-04
## ASV1881     -6.060156e-05 -6.343618e-05 -6.640071e-05 -6.950083e-05
## ASV1089      3.630744e-04  3.796011e-04  3.968445e-04  4.148322e-04
## ASV1450     -7.441057e-05 -7.769884e-05 -8.112077e-05 -8.468076e-05
## ASV4643     -2.073274e-04 -2.167378e-04 -2.265536e-04 -2.367903e-04
## ASV3458      1.023879e-04  1.071690e-04  1.121636e-04  1.173801e-04
## ASV2543     -9.126839e-05 -9.563457e-05 -1.002097e-04 -1.050037e-04
## ASV3306     -1.034537e-04 -1.082799e-04 -1.133212e-04 -1.185861e-04
## ASV0218     -2.024545e-04 -2.117977e-04 -2.215592e-04 -2.317564e-04
## ASV3727      1.360409e-04  1.426181e-04  1.495159e-04  1.567501e-04
## ASV4394     -1.466610e-04 -1.536293e-04 -1.609261e-04 -1.685663e-04
## ASV2636      1.219656e-05  1.334955e-05  1.460764e-05  1.597996e-05
## ASV5116      3.648535e-05  3.809414e-05  3.976803e-05  4.150916e-05
## ASV1394     -3.603366e-04 -3.769316e-04 -3.942648e-04 -4.123669e-04
## ASV0656     -3.530867e-04 -3.690585e-04 -3.857142e-04 -4.030796e-04
## ASV0475      5.373466e-04  5.622144e-04  5.881989e-04  6.153470e-04
## ASV1042      1.341185e-04  1.402841e-04  1.467221e-04  1.534436e-04
## ASV1199     -2.774215e-04 -2.903599e-04 -3.038890e-04 -3.180347e-04
## ASV12962    -1.843943e-05 -1.920321e-05 -1.999337e-05 -2.081035e-05
## ASV0853      2.511804e-04  2.626316e-04  2.745786e-04  2.870402e-04
## ASV5069     -5.813901e-05 -6.155883e-05 -6.519320e-05 -6.905589e-05
## ASV7825     -1.567972e-04 -1.640228e-04 -1.715696e-04 -1.794507e-04
## ASV0339      1.756470e-04  1.837385e-04  1.921904e-04  2.010177e-04
## ASV2965      1.530131e-04  1.600861e-04  1.674756e-04  1.751947e-04
## ASV2347     -2.028631e-04 -2.119099e-04 -2.213331e-04 -2.311460e-04
## ASV0541      8.942692e-05  9.384075e-05  9.847713e-05  1.033475e-04
## ASV0369      2.380198e-04  2.488426e-04  2.601339e-04  2.719119e-04
## ASV0171      1.205415e-04  1.261011e-04  1.319099e-04  1.379783e-04
## ASV2235      2.885262e-04  3.010753e-04  3.141185e-04  3.276710e-04
## ASV5809     -2.712410e-04 -2.834958e-04 -2.962736e-04 -3.095940e-04
## ASV1267      3.417797e-04  3.573227e-04  3.735377e-04  3.904506e-04
## ASV0207     -3.679421e-04 -3.846024e-04 -4.019768e-04 -4.200921e-04
## ASV3126     -4.356532e-04 -4.558927e-04 -4.770478e-04 -4.991577e-04
## ASV0183     -4.799220e-04 -5.018772e-04 -5.247955e-04 -5.487153e-04
## ASV1792      1.642200e-04  1.715277e-04  1.791367e-04  1.870575e-04
## ASV2001     -4.236664e-04 -4.434146e-04 -4.640634e-04 -4.856523e-04
## ASV5732     -4.162793e-04 -4.353217e-04 -4.551983e-04 -4.759425e-04
## ASV2857     -2.638658e-04 -2.760957e-04 -2.888770e-04 -3.022333e-04
## ASV1052     -1.920801e-04 -2.007350e-04 -2.097592e-04 -2.191670e-04
## ASV3226     -1.223972e-04 -1.280224e-04 -1.338967e-04 -1.400301e-04
## ASV3766     -4.526420e-05 -4.737247e-05 -4.957685e-05 -5.188154e-05
## ASV0982     -1.325310e-04 -1.388877e-04 -1.455501e-04 -1.525329e-04
## ASV0489     -3.215186e-06 -3.743575e-06 -4.329428e-06 -4.978046e-06
## ASV3990     -4.529840e-04 -4.739765e-04 -4.959146e-04 -5.188383e-04
## ASV0433     -2.685638e-04 -2.806098e-04 -2.931610e-04 -3.062350e-04
## ASV0684     -1.161707e-04 -1.217552e-04 -1.276107e-04 -1.337505e-04
## ASV0063     -3.179819e-04 -3.325364e-04 -3.477286e-04 -3.635837e-04
## ASV1399      5.392888e-05  5.594452e-05  5.800665e-05  6.011324e-05
## ASV3093     -5.398962e-04 -5.650752e-04 -5.914036e-04 -6.189317e-04
## ASV1771      6.626000e-05  6.947301e-05  7.284340e-05  7.637894e-05
## ASV7910     -2.716424e-04 -2.834171e-04 -2.956511e-04 -3.083579e-04
## ASV3718     -3.612344e-04 -3.778501e-04 -3.952026e-04 -4.133222e-04
## ASV0039     -2.846045e-04 -2.980533e-04 -3.121296e-04 -3.268616e-04
## ASV6469     -5.902116e-04 -6.171542e-04 -6.452719e-04 -6.746109e-04
## ASV8186     -3.998171e-04 -4.181961e-04 -4.373893e-04 -4.574300e-04
## ASV1091     -4.081142e-05 -4.279980e-05 -4.488646e-05 -4.707630e-05
## ASV16930    -4.888708e-04 -5.114153e-04 -5.349649e-04 -5.595612e-04
## ASV7234     -3.660635e-04 -3.829167e-04 -4.005187e-04 -4.189004e-04
## ASV1560     -4.405046e-05 -4.614341e-05 -4.833513e-05 -5.063018e-05
## ASV2968      7.412694e-05  7.773057e-05  8.151207e-05  8.548041e-05
## ASV3824     -3.763088e-04 -3.934817e-04 -4.114041e-04 -4.301058e-04
## ASV0442     -2.347728e-04 -2.456821e-04 -2.570851e-04 -2.690031e-04
## ASV0677     -1.783220e-04 -1.860448e-04 -1.940676e-04 -2.023990e-04
## ASV4796     -2.503128e-04 -2.615908e-04 -2.733495e-04 -2.856071e-04
## ASV2206     -3.996191e-04 -4.180871e-04 -4.373824e-04 -4.575393e-04
## ASV2884      7.962277e-05  8.330764e-05  8.715776e-05  9.118003e-05
## ASV0482     -1.450710e-04 -1.518222e-04 -1.588802e-04 -1.662583e-04
## ASV1273      3.320555e-04  3.475114e-04  3.636663e-04  3.805498e-04
## ASV1910      4.389843e-05  4.565427e-05  4.746446e-05  4.932919e-05
## ASV0105      2.512557e-04  2.624045e-04  2.740107e-04  2.860898e-04
## ASV0149      2.665521e-04  2.788099e-04  2.916109e-04  3.049771e-04
## ASV5007     -4.152913e-04 -4.345107e-04 -4.545930e-04 -4.755746e-04
## ASV0757      3.586484e-04  3.753049e-04  3.927152e-04  4.109116e-04
## ASV11952    -2.972381e-04 -3.106513e-04 -3.246351e-04 -3.392107e-04
## ASV4102      2.367313e-04  2.476968e-04  2.591551e-04  2.711269e-04
## ASV1034      2.986139e-04  3.122011e-04  3.263784e-04  3.411687e-04
## ASV0753      2.217601e-04  2.319282e-04  2.425446e-04  2.536276e-04
## ASV2323      1.344966e-04  1.407901e-04  1.473723e-04  1.542561e-04
## ASV0881     -1.048396e-04 -1.095086e-04 -1.143699e-04 -1.194300e-04
## ASV3730     -2.783955e-04 -2.911344e-04 -3.044318e-04 -3.183102e-04
## ASV2685     -1.066670e-04 -1.113098e-04 -1.161339e-04 -1.211444e-04
## ASV3826     -5.271110e-05 -5.514531e-05 -5.768904e-05 -6.034701e-05
## ASV0689      2.444436e-05  2.579460e-05  2.722539e-05  2.874188e-05
## ASV4315     -3.646890e-04 -3.815853e-04 -3.992425e-04 -4.176930e-04
## ASV1239      1.759447e-04  1.834716e-04  1.912835e-04  1.993882e-04
## ASV3147     -6.064987e-05 -6.356098e-05 -6.661232e-05 -6.981064e-05
## ASV3454     -2.720866e-04 -2.845268e-04 -2.975121e-04 -3.110645e-04
## ASV4411     -1.621854e-04 -1.698832e-04 -1.779452e-04 -1.863884e-04
## ASV3007      3.253706e-04  3.399988e-04  3.552446e-04  3.711305e-04
## ASV6151     -2.638605e-04 -2.756067e-04 -2.878405e-04 -3.005789e-04
## ASV0834      2.773660e-04  2.903114e-04  3.038477e-04  3.180006e-04
## ASV1231      3.981241e-04  4.163891e-04  4.354593e-04  4.553673e-04
## ASV0643      3.356515e-04  3.510273e-04  3.670788e-04  3.838329e-04
## ASV0924      9.720892e-06  1.017024e-05  1.063858e-05  1.112647e-05
## ASV3238     -1.657768e-04 -1.732055e-04 -1.809456e-04 -1.890081e-04
## ASV1276     -1.951464e-04 -2.040765e-04 -2.133981e-04 -2.231268e-04
## ASV5503     -5.278275e-04 -5.518331e-04 -5.768774e-04 -6.030005e-04
## ASV0404      2.125463e-04  2.224364e-04  2.327751e-04  2.435819e-04
## ASV3430      3.238844e-05  3.448537e-05  3.673048e-05  3.913474e-05
## ASV5401     -2.256141e-04 -2.360576e-04 -2.469703e-04 -2.583719e-04
## ASV3426     -4.809037e-04 -5.028844e-04 -5.258268e-04 -5.497692e-04
## ASV0777      2.862061e-04  2.993112e-04  3.129920e-04  3.272714e-04
## ASV11093    -1.923986e-04 -2.012226e-04 -2.104360e-04 -2.200544e-04
## ASV2170     -1.673982e-04 -1.748927e-04 -1.827006e-04 -1.908329e-04
## ASV3861      1.517405e-04  1.583653e-04  1.652515e-04  1.724069e-04
## ASV1723     -2.798588e-04 -2.927731e-04 -3.062637e-04 -3.203544e-04
## ASV2460     -1.585301e-04 -1.659229e-04 -1.736526e-04 -1.817339e-04
## ASV1218     -2.297508e-04 -2.400918e-04 -2.508712e-04 -2.621052e-04
## ASV0436      1.460840e-05  1.498334e-05  1.534804e-05  1.569969e-05
## ASV0919      1.958296e-04  2.047073e-04  2.139672e-04  2.236239e-04
## ASV0577      8.376455e-05  8.753873e-05  9.147284e-05  9.557272e-05
## ASV2517      2.227418e-04  2.327779e-04  2.432395e-04  2.541421e-04
## ASV2628     -2.709189e-04 -2.834810e-04 -2.966084e-04 -3.103247e-04
## ASV1743     -2.471653e-04 -2.587390e-04 -2.708445e-04 -2.835054e-04
## ASV1678     -2.132036e-04 -2.232670e-04 -2.338006e-04 -2.448257e-04
## ASV0315      2.777224e-04  2.905630e-04  3.039792e-04  3.179953e-04
## ASV0253      1.294541e-04  1.353518e-04  1.415053e-04  1.479244e-04
## ASV1363      3.511679e-04  3.668381e-04  3.831583e-04  4.001513e-04
## ASV0995     -1.934800e-04 -2.024300e-04 -2.117817e-04 -2.215521e-04
## ASV4185     -8.468215e-05 -8.834085e-05 -9.214088e-05 -9.608626e-05
## ASV0782      1.762977e-04  1.846433e-04  1.933816e-04  2.025308e-04
## ASV3240     -2.097738e-04 -2.195581e-04 -2.297893e-04 -2.404870e-04
## ASV1392     -3.805920e-04 -3.982891e-04 -4.167891e-04 -4.361268e-04
## ASV8488     -8.654984e-05 -9.058600e-05 -9.480700e-05 -9.922104e-05
## ASV2814     -1.411309e-04 -1.476749e-04 -1.545147e-04 -1.616631e-04
## ASV0678     -2.873592e-04 -3.009961e-04 -3.152769e-04 -3.302317e-04
## ASV1295     -2.009942e-04 -2.102756e-04 -2.199723e-04 -2.301016e-04
## ASV7517     -1.220765e-04 -1.274655e-04 -1.330730e-04 -1.389062e-04
## ASV2996     -3.917015e-04 -4.095676e-04 -4.282118e-04 -4.476647e-04
## ASV2882     -3.680372e-04 -3.847172e-04 -4.021147e-04 -4.202572e-04
## ASV1317      2.266114e-04  2.371119e-04  2.480845e-04  2.595491e-04
## ASV9106     -3.743984e-04 -3.916772e-04 -4.097277e-04 -4.285817e-04
## ASV9688     -3.562899e-04 -3.727221e-04 -3.898866e-04 -4.078137e-04
## ASV6181     -3.555752e-04 -3.719214e-04 -3.889914e-04 -4.068149e-04
## ASV2936      1.059411e-05  1.118363e-05  1.180848e-05  1.247091e-05
## ASV0192     -1.467234e-04 -1.532242e-04 -1.599893e-04 -1.670272e-04
## ASV2509     -1.796028e-04 -1.881349e-04 -1.970697e-04 -2.064259e-04
## ASV0863      6.222772e-04  6.501600e-04  6.792125e-04  7.094768e-04
## ASV2762     -1.600588e-04 -1.674644e-04 -1.752033e-04 -1.832896e-04
## ASV4904     -3.406754e-04 -3.563385e-04 -3.726954e-04 -3.897745e-04
## ASV0571      1.163590e-04  1.216008e-04  1.270667e-04  1.327654e-04
## ASV13304    -5.443625e-05 -5.728038e-05 -6.028133e-05 -6.344821e-05
## ASV6863     -7.730077e-05 -8.088047e-05 -8.462197e-05 -8.853228e-05
## ASV4844      2.861515e-05  3.026207e-05  3.201290e-05  3.387475e-05
## ASV10779    -3.739712e-04 -3.910741e-04 -4.089260e-04 -4.275569e-04
## ASV7921     -3.156582e-04 -3.302205e-04 -3.454327e-04 -3.613219e-04
## ASV8458     -3.292389e-04 -3.441571e-04 -3.597158e-04 -3.759393e-04
## ASV2593     -4.443933e-05 -4.615884e-05 -4.792452e-05 -4.973551e-05
## ASV4410     -1.789707e-04 -1.872638e-04 -1.959299e-04 -2.049849e-04
## ASV0593      4.594720e-04  4.810661e-04  5.036579e-04  5.272916e-04
## ASV2669      2.679113e-04  2.799443e-04  2.924837e-04  3.055476e-04
## ASV0868     -3.516973e-04 -3.679103e-04 -3.848455e-04 -4.025330e-04
## ASV3123     -1.240552e-04 -1.300067e-04 -1.362426e-04 -1.427762e-04
## ASV3482     -1.431660e-04 -1.496830e-04 -1.564824e-04 -1.635750e-04
## ASV2552     -3.954723e-04 -4.129599e-04 -4.311599e-04 -4.500957e-04
## ASV0723      4.503419e-04  4.702968e-04  4.910683e-04  5.126840e-04
## ASV0526     -2.992216e-04 -3.130009e-04 -3.273939e-04 -3.424262e-04
## ASV4623     -1.352024e-04 -1.415049e-04 -1.480944e-04 -1.549832e-04
## ASV2070     -4.170980e-04 -4.362469e-04 -4.562415e-04 -4.771163e-04
## ASV1198      1.059472e-05  1.103229e-05  1.148462e-05  1.195186e-05
## ASV3034      1.736810e-05  1.806492e-05  1.878388e-05  1.952518e-05
## ASV1208     -4.948317e-05 -5.173667e-05 -5.408842e-05 -5.654233e-05
## ASV4860      6.766922e-05  7.086185e-05  7.420279e-05  7.769863e-05
## ASV2493     -1.291720e-04 -1.351206e-04 -1.413341e-04 -1.478233e-04
## ASV4217     -8.892701e-05 -9.278177e-05 -9.678530e-05 -1.009416e-04
## ASV1516     -5.674314e-05 -5.977742e-05 -6.298561e-05 -6.637841e-05
## ASV1186      1.542537e-04  1.613688e-04  1.688014e-04  1.765647e-04
## ASV1906     -1.342075e-04 -1.404460e-04 -1.469674e-04 -1.537841e-04
## ASV8220     -2.119107e-05 -2.235408e-05 -2.358630e-05 -2.489221e-05
## ASV4227     -3.059067e-04 -3.199616e-04 -3.346385e-04 -3.499626e-04
## ASV1013      1.922120e-04  2.013778e-04  2.109785e-04  2.210342e-04
## ASV7952     -2.077605e-04 -2.176665e-04 -2.280438e-04 -2.389145e-04
## ASV5923     -2.362398e-04 -2.472471e-04 -2.587557e-04 -2.707870e-04
## ASV0190     -2.930026e-04 -3.062544e-04 -3.200728e-04 -3.344790e-04
## ASV0491     -3.226593e-05 -3.395678e-05 -3.574162e-05 -3.762605e-05
## ASV9535     -1.260873e-04 -1.318947e-04 -1.379598e-04 -1.442930e-04
## ASV9947     -9.469320e-05 -9.941293e-05 -1.043754e-04 -1.095937e-04
## ASV6518     -8.241895e-05 -8.621151e-05 -9.017262e-05 -9.430925e-05
## ASV1741     -8.482141e-05 -8.883148e-05 -9.302928e-05 -9.742335e-05
## ASV1874      1.594090e-04  1.664841e-04  1.738487e-04  1.815122e-04
## ASV2150      4.535936e-05  4.747120e-05  4.967899e-05  5.198686e-05
## ASV5262     -8.386909e-05 -8.764906e-05 -9.158950e-05 -9.569633e-05
## ASV1729     -3.025304e-04 -3.165661e-04 -3.312355e-04 -3.465655e-04
## ASV1522     -5.874854e-05 -6.183020e-05 -6.508027e-05 -6.850812e-05
## ASV3250      6.459404e-05  6.746378e-05  7.045159e-05  7.356152e-05
## ASV4338     -3.055449e-04 -3.196180e-04 -3.343171e-04 -3.496679e-04
## ASV1386      3.648621e-04  3.817374e-04  3.993696e-04  4.177904e-04
## ASV0694     -4.137662e-05 -4.346090e-05 -4.565468e-05 -4.796402e-05
## ASV2026      3.298965e-05  3.479880e-05  3.671470e-05  3.874408e-05
## ASV0191     -2.429185e-04 -2.538328e-04 -2.652069e-04 -2.770572e-04
## ASV1641      1.183989e-04  1.240099e-04  1.298833e-04  1.360310e-04
## ASV1326      5.914118e-04  6.185961e-04  6.469839e-04  6.766241e-04
## ASV4786     -1.777695e-05 -1.868551e-05 -1.964286e-05 -2.065181e-05
## ASV0342      1.487123e-04  1.557266e-04  1.630678e-04  1.707506e-04
## ASV3025     -1.718633e-04 -1.795669e-04 -1.875940e-04 -1.959562e-04
## ASV6533     -2.947172e-04 -3.080469e-04 -3.219473e-04 -3.364399e-04
## ASV1898      3.303130e-04  3.456201e-04  3.616147e-04  3.783256e-04
## ASV1940      1.873069e-04  1.959434e-04  2.049641e-04  2.143846e-04
## ASV4968     -3.420184e-04 -3.578651e-04 -3.744253e-04 -3.917292e-04
## ASV3401     -1.792725e-04 -1.875141e-04 -1.961209e-04 -2.051079e-04
## ASV3211      1.078174e-04  1.129751e-04  1.183792e-04  1.240412e-04
## ASV1489     -4.750005e-04 -4.967772e-04 -5.195120e-04 -5.432435e-04
## ASV4139     -2.785143e-04 -2.913503e-04 -3.047578e-04 -3.187606e-04
## ASV6059     -2.939501e-04 -3.075085e-04 -3.216720e-04 -3.364658e-04
## ASV0918      7.418791e-05  7.742437e-05  8.078828e-05  8.428343e-05
## ASV1449      2.856241e-04  2.987869e-04  3.125359e-04  3.268952e-04
## ASV5652     -1.962991e-04 -2.053253e-04 -2.147513e-04 -2.245935e-04
## ASV4091     -6.050586e-06 -5.962062e-06 -5.836022e-06 -5.667906e-06
## ASV7638     -1.822010e-04 -1.904508e-04 -1.990541e-04 -2.080245e-04
## ASV6525     -2.564867e-04 -2.679413e-04 -2.798744e-04 -2.923029e-04
## ASV8959     -2.654712e-04 -2.777621e-04 -2.906054e-04 -3.040243e-04
## ASV0699      2.028270e-04  2.121349e-04  2.218513e-04  2.319921e-04
## ASV2925      2.488401e-04  2.604169e-04  2.725190e-04  2.851692e-04
## ASV0618      5.502483e-05  5.771084e-05  6.052896e-05  6.348561e-05
## ASV2083      3.846607e-05  4.036148e-05  4.235245e-05  4.444392e-05
## ASV6192     -3.234459e-04 -3.382555e-04 -3.537153e-04 -3.698512e-04
## ASV8640     -3.656896e-04 -3.824490e-04 -3.999462e-04 -4.182107e-04
## ASV1103      1.500248e-04  1.567797e-04  1.638214e-04  1.711606e-04
## ASV4240     -1.773294e-05 -1.826442e-05 -1.879405e-05 -1.931955e-05
## ASV2180      9.518195e-05  9.953064e-05  1.040697e-04  1.088066e-04
## ASV9157     -2.344043e-04 -2.451187e-04 -2.563015e-04 -2.679713e-04
## ASV1307      4.603258e-04  4.816450e-04  5.039232e-04  5.272009e-04
## ASV4960     -1.146929e-04 -1.198220e-04 -1.251654e-04 -1.307305e-04
## ASV3930     -9.764181e-05 -1.020166e-04 -1.065755e-04 -1.113250e-04
## ASV1200     -2.014429e-04 -2.107905e-04 -2.205598e-04 -2.307687e-04
## ASV4676     -1.023502e-04 -1.070377e-04 -1.119313e-04 -1.170391e-04
## ASV6993     -3.802737e-04 -3.975026e-04 -4.154713e-04 -4.342077e-04
## ASV4813     -1.488843e-04 -1.557181e-04 -1.628534e-04 -1.703022e-04
## ASV4364     -4.904797e-04 -5.127607e-04 -5.360041e-04 -5.602468e-04
## ASV0141      1.946834e-04  2.030973e-04  2.118359e-04  2.209084e-04
## ASV3509      1.235583e-04  1.295519e-04  1.358405e-04  1.424387e-04
## ASV2751      2.070114e-04  2.165836e-04  2.265850e-04  2.370338e-04
## ASV4913     -2.120592e-04 -2.217367e-04 -2.318366e-04 -2.423756e-04
## ASV0138      5.253956e-04  5.495201e-04  5.747113e-04  6.010130e-04
## ASV7697     -1.476246e-04 -1.542182e-04 -1.610860e-04 -1.682376e-04
## ASV1602      7.551537e-05  7.865330e-05  8.189950e-05  8.525559e-05
## ASV5976     -2.943864e-04 -3.078718e-04 -3.219504e-04 -3.366459e-04
## ASV7525     -3.032426e-04 -3.171070e-04 -3.315788e-04 -3.466821e-04
## ASV4961      1.370264e-04  1.432714e-04  1.497871e-04  1.565841e-04
## ASV2546      3.697116e-04  3.861456e-04  4.032575e-04  4.210707e-04
## ASV0721     -2.234561e-04 -2.336865e-04 -2.443656e-04 -2.555113e-04
## ASV0542      2.053217e-04  2.147047e-04  2.244985e-04  2.347196e-04
## ASV3865      1.313919e-04  1.373020e-04  1.434617e-04  1.498803e-04
## ASV5571     -2.380777e-04 -2.486509e-04 -2.596582e-04 -2.711142e-04
## ASV6804      2.976564e-05  3.136141e-05  3.304903e-05  3.483422e-05
## ASV4424      2.206854e-04  2.308689e-04  2.415063e-04  2.526161e-04
## ASV3395      1.619901e-04  1.689709e-04  1.762197e-04  1.837440e-04
## ASV2394     -2.176214e-04 -2.276771e-04 -2.381830e-04 -2.491582e-04
## ASV8629     -2.176035e-04 -2.276575e-04 -2.381616e-04 -2.491347e-04
## ASV1018      1.970420e-04  2.061195e-04  2.156013e-04  2.255039e-04
## ASV6139     -4.410774e-04 -4.613610e-04 -4.825433e-04 -5.046608e-04
## ASV10411    -2.262491e-04 -2.366990e-04 -2.476163e-04 -2.590207e-04
## ASV3992     -8.795934e-05 -9.208502e-05 -9.640124e-05 -1.009165e-04
## ASV7131     -1.737345e-05 -1.820376e-05 -1.907410e-05 -1.998644e-05
## ASV3729     -3.703288e-05 -3.853173e-05 -4.007771e-05 -4.167091e-05
## ASV2197     -4.862328e-05 -5.080525e-05 -5.307917e-05 -5.544840e-05
## ASV2426     -2.272715e-04 -2.375335e-04 -2.482331e-04 -2.593867e-04
## ASV3669     -2.127377e-04 -2.227487e-04 -2.332250e-04 -2.441878e-04
## ASV1820      1.121533e-04  1.172453e-04  1.225565e-04  1.280954e-04
## ASV7081     -2.014078e-04 -2.107267e-04 -2.204644e-04 -2.306386e-04
## ASV7872     -2.559859e-04 -2.676412e-04 -2.798024e-04 -2.924891e-04
## ASV1670     -3.088590e-05 -3.213940e-05 -3.343282e-05 -3.476631e-05
## ASV0712      2.477654e-04  2.595993e-04  2.719976e-04  2.849871e-04
## ASV0474      3.804006e-04  3.971089e-04  4.144884e-04  4.325606e-04
## ASV1196      3.768688e-04  3.942641e-04  4.124364e-04  4.314182e-04
## ASV0845      2.369749e-04  2.477617e-04  2.590175e-04  2.707606e-04
## ASV12393    -4.805201e-04 -5.026863e-04 -5.258408e-04 -5.500244e-04
## ASV5867     -1.849071e-04 -1.934874e-04 -2.024544e-04 -2.118246e-04
## ASV17619    -6.984146e-05 -7.325333e-05 -7.683522e-05 -8.059584e-05
## ASV4686     -1.632888e-04 -1.709001e-04 -1.788586e-04 -1.871794e-04
## ASV3520     -2.659057e-04 -2.781261e-04 -2.908876e-04 -3.042124e-04
## ASV10800    -4.346428e-04 -4.547502e-04 -4.757598e-04 -4.977096e-04
## ASV2706      3.856263e-04  4.035418e-04  4.222677e-04  4.418388e-04
## ASV1227     -5.387275e-05 -5.625747e-05 -5.873939e-05 -6.132172e-05
## ASV2621      3.540920e-04  3.707543e-04  3.881903e-04  4.064348e-04
## ASV0460      7.908488e-05  8.289311e-05  8.688571e-05  9.107162e-05
## ASV1069     -2.896224e-04 -3.031124e-04 -3.172163e-04 -3.319606e-04
## ASV6939     -2.672767e-04 -2.794648e-04 -2.921837e-04 -3.054543e-04
## ASV2862     -3.714104e-04 -3.884638e-04 -4.062706e-04 -4.248613e-04
## ASV1021     -2.178200e-04 -2.276198e-04 -2.378340e-04 -2.484778e-04
## ASV3845      1.725536e-04  1.805573e-04  1.889213e-04  1.976608e-04
## ASV0732      1.512328e-04  1.583736e-04  1.658479e-04  1.736709e-04
## ASV10731     1.166184e-04  1.219111e-04  1.274316e-04  1.331887e-04
## ASV3378      1.392138e-04  1.453270e-04  1.516848e-04  1.582948e-04
## ASV7154      1.118991e-05  1.144368e-05  1.168412e-05  1.190840e-05
## ASV9876      6.480490e-05  6.788811e-05  7.111729e-05  7.449923e-05
## ASV0631      2.908798e-04  3.045288e-04  3.188084e-04  3.337469e-04
## ASV13027    -2.200189e-04 -2.303010e-04 -2.410544e-04 -2.522998e-04
## ASV2497     -2.200006e-04 -2.302809e-04 -2.410324e-04 -2.522757e-04
## ASV3966     -3.102262e-04 -3.247562e-04 -3.399550e-04 -3.558524e-04
## ASV2574      1.849807e-04  1.931947e-04  2.017454e-04  2.106443e-04
## ASV0545     -1.722253e-04 -1.803285e-04 -1.888066e-04 -1.976764e-04
## ASV8453     -1.953052e-04 -2.044237e-04 -2.139595e-04 -2.239310e-04
## ASV0221     -1.032866e-04 -1.080812e-04 -1.130925e-04 -1.183300e-04
## ASV3305      1.395233e-04  1.461256e-04  1.530378e-04  1.602745e-04
## ASV2647     -9.618270e-05 -1.004951e-04 -1.049883e-04 -1.096687e-04
## ASV5789     -4.453702e-04 -4.662280e-04 -4.880459e-04 -5.108665e-04
## ASV1731     -1.409015e-04 -1.470158e-04 -1.533685e-04 -1.599667e-04
## ASV3857      6.243441e-05  6.523770e-05  6.815924e-05  7.120334e-05
## ASV0405      2.623617e-04  2.741039e-04  2.863367e-04  2.990776e-04
## ASV0094     -3.003119e-04 -3.133388e-04 -3.268760e-04 -3.409390e-04
## ASV0158     -1.088521e-05 -1.117418e-05 -1.145785e-05 -1.173453e-05
## ASV5507     -2.626860e-04 -2.747799e-04 -2.874114e-04 -3.006029e-04
## ASV1023     -2.328943e-06 -2.113143e-06 -1.857235e-06 -1.556682e-06
## ASV0488     -1.708276e-04 -1.787210e-04 -1.869675e-04 -1.955819e-04
## ASV1459      1.435521e-04  1.499153e-04  1.565396e-04  1.634341e-04
## ASV4349     -4.316520e-05 -4.498080e-05 -4.686154e-05 -4.880872e-05
## ASV1172      4.429731e-04  4.631733e-04  4.842529e-04  5.062466e-04
## ASV10187    -1.162799e-04 -1.217905e-04 -1.275608e-04 -1.336027e-04
## ASV7227      6.880831e-05  7.203721e-05  7.541538e-05  7.894950e-05
## ASV10340     6.745836e-05  7.068529e-05  7.406713e-05  7.761135e-05
## ASV10821    -1.254660e-04 -1.312301e-04 -1.372490e-04 -1.435329e-04
## ASV13810    -1.254558e-04 -1.312189e-04 -1.372367e-04 -1.435194e-04
## ASV3230     -1.007481e-04 -1.053900e-04 -1.102383e-04 -1.153013e-04
## ASV5524      1.051781e-05  1.091420e-05  1.132008e-05  1.173509e-05
## ASV8742     -1.254379e-04 -1.311993e-04 -1.372153e-04 -1.434960e-04
## ASV9188      2.770735e-04  2.894577e-04  3.023574e-04  3.157907e-04
## ASV4658      1.403870e-04  1.468503e-04  1.536004e-04  1.606491e-04
## ASV7889      1.710130e-04  1.785577e-04  1.864089e-04  1.945769e-04
## ASV1466      3.973366e-05  4.186030e-05  4.410853e-05  4.648578e-05
## ASV1424     -8.091235e-05 -8.409428e-05 -8.736755e-05 -9.073136e-05
## ASV0098     -2.159594e-04 -2.260618e-04 -2.366268e-04 -2.476745e-04
## ASV0067     -3.453522e-04 -3.612501e-04 -3.778538e-04 -3.951924e-04
## ASV9434     -1.433998e-04 -1.499585e-04 -1.568045e-04 -1.639492e-04
## ASV3270     -5.664916e-05 -5.935206e-05 -6.218324e-05 -6.514864e-05
## ASV4518     -2.456747e-04 -2.568269e-04 -2.684597e-04 -2.805918e-04
## ASV7661     -2.311421e-04 -2.414540e-04 -2.521940e-04 -2.633768e-04
## ASV4223      2.638954e-05  2.763579e-05  2.893975e-05  3.030392e-05
## ASV3481      1.970925e-04  2.066856e-04  2.167536e-04  2.273206e-04
## ASV7819     -3.626931e-04 -3.793805e-04 -3.968087e-04 -4.150081e-04
## ASV3095     -1.550249e-05 -1.614924e-05 -1.681805e-05 -1.750911e-05
## ASV4476     -7.447354e-05 -7.800774e-05 -8.170887e-05 -8.558472e-05
## ASV1713      2.188264e-04  2.285234e-04  2.386172e-04  2.491211e-04
## ASV11165    -5.719912e-05 -5.967613e-05 -6.224839e-05 -6.491841e-05
## ASV2179      4.493305e-04  4.700566e-04  4.917069e-04  5.143197e-04
## ASV3747      3.852141e-04  4.029636e-04  4.215025e-04  4.408632e-04
## ASV1410      2.076503e-05  2.150888e-05  2.226667e-05  2.303730e-05
## ASV6069     -2.419838e-04 -2.531494e-04 -2.648136e-04 -2.769970e-04
## ASV1939      6.710804e-05  7.034203e-05  7.373299e-05  7.728858e-05
## ASV7865     -3.771808e-04 -3.945488e-04 -4.126881e-04 -4.316304e-04
## ASV4488     -3.466043e-04 -3.627412e-04 -3.796118e-04 -3.972479e-04
## ASV0938      2.741117e-04  2.866769e-04  2.997952e-04  3.134890e-04
## ASV7852     -2.081687e-04 -2.175901e-04 -2.274157e-04 -2.376609e-04
## ASV2503     -1.937169e-05 -2.044437e-05 -2.158234e-05 -2.279002e-05
## ASV2993     -2.968190e-04 -3.106095e-04 -3.250240e-04 -3.400892e-04
## ASV3752     -3.665321e-05 -3.829555e-05 -4.000677e-05 -4.178937e-05
## ASV2557     -3.023853e-04 -3.164491e-04 -3.311495e-04 -3.465136e-04
## ASV6522     -6.256878e-05 -6.536802e-05 -6.828405e-05 -7.132098e-05
## ASV0088     -2.249750e-04 -2.348161e-04 -2.450476e-04 -2.556815e-04
## ASV7935     -1.873286e-04 -1.958981e-04 -2.048434e-04 -2.141794e-04
## ASV0942     -2.384518e-04 -2.495419e-04 -2.611346e-04 -2.732514e-04
## ASV7709     -2.794388e-04 -2.919876e-04 -3.050649e-04 -3.186899e-04
## ASV4588     -1.431605e-04 -1.494565e-04 -1.560060e-04 -1.628172e-04
## ASV5765     -3.981767e-04 -4.164384e-04 -4.355047e-04 -4.554081e-04
## ASV3562     -2.049483e-05 -2.123260e-05 -2.198377e-05 -2.274707e-05
## ASV9076     -3.044013e-04 -3.184426e-04 -3.331105e-04 -3.484308e-04
## ASV4707     -3.396030e-04 -3.553092e-04 -3.717197e-04 -3.888641e-04
## ASV2188      2.417170e-04  2.530435e-04  2.648920e-04  2.772854e-04
## ASV0613      4.486075e-05  4.713347e-05  4.952487e-05  5.204124e-05
## ASV0663     -1.530449e-04 -1.601487e-04 -1.675735e-04 -1.753331e-04
## ASV3361     -3.040553e-04 -3.173272e-04 -3.311242e-04 -3.454624e-04
## ASV1478      3.372752e-04  3.526024e-04  3.685920e-04  3.852695e-04
## ASV0213      1.873545e-04  1.959001e-04  2.048180e-04  2.141228e-04
## ASV7674     -1.025581e-04 -1.071780e-04 -1.119942e-04 -1.170139e-04
## ASV2137     -1.099607e-04 -1.148765e-04 -1.199970e-04 -1.253296e-04
## ASV8246     -9.157437e-05 -9.572810e-05 -1.000610e-04 -1.045799e-04
## ASV0047     -2.903078e-04 -3.034021e-04 -3.170533e-04 -3.312822e-04
## ASV6117      9.851441e-06  1.041563e-05  1.101467e-05  1.165084e-05
## ASV3349     -5.545730e-05 -5.801578e-05 -6.068837e-05 -6.347980e-05
## ASV10881    -1.900949e-04 -1.988504e-04 -2.079949e-04 -2.175442e-04
## ASV6979     -1.284104e-04 -1.344023e-04 -1.406678e-04 -1.472187e-04
## ASV7930     -2.485964e-04 -2.599815e-04 -2.718669e-04 -2.842728e-04
## ASV7322      8.342640e-05  8.729582e-05  9.133958e-05  9.556505e-05
## ASV4927     -4.209192e-05 -4.413012e-05 -4.626795e-05 -4.851029e-05
## ASV9054     -1.388774e-04 -1.451827e-04 -1.517606e-04 -1.586217e-04
## ASV2692     -1.076142e-04 -1.128443e-04 -1.183287e-04 -1.240795e-04
## ASV1666     -7.386776e-05 -7.695592e-05 -8.015260e-05 -8.345966e-05
## ASV4728      1.596028e-04  1.667617e-04  1.742222e-04  1.819953e-04
## ASV3097      1.063177e-04  1.113312e-04  1.165785e-04  1.220704e-04
## ASV4962     -8.542554e-05 -8.965149e-05 -9.409165e-05 -9.875716e-05
## ASV5057      1.303637e-04  1.365473e-04  1.430229e-04  1.498040e-04
## ASV2639      2.358191e-04  2.469564e-04  2.586143e-04  2.708165e-04
## ASV1808     -2.813742e-05 -2.984351e-05 -3.166183e-05 -3.360012e-05
## ASV6333     -4.445617e-05 -4.674495e-05 -4.915790e-05 -5.170219e-05
## ASV4328     -1.056029e-04 -1.104504e-04 -1.155118e-04 -1.207958e-04
## ASV7707     -3.109029e-04 -3.250125e-04 -3.397296e-04 -3.550775e-04
## ASV11022    -3.016586e-04 -3.153047e-04 -3.295348e-04 -3.443709e-04
## ASV1469     -5.640988e-05 -5.896103e-05 -6.162162e-05 -6.439582e-05
## ASV3919     -1.040182e-04 -1.089498e-04 -1.141132e-04 -1.195191e-04
## ASV4038     -2.110610e-04 -2.207175e-04 -2.307976e-04 -2.413184e-04
## ASV4048      7.545032e-05  7.914076e-05  8.301466e-05  8.708129e-05
## ASV0634      8.721141e-05  9.131922e-05  9.561872e-05  1.001187e-04
## ASV1852     -2.377189e-04 -2.490070e-04 -2.608283e-04 -2.732074e-04
## ASV2505      1.788145e-04  1.870139e-04  1.955753e-04  2.045134e-04
## ASV1762     -2.744788e-04 -2.870207e-04 -3.001112e-04 -3.137721e-04
## ASV3761     -2.329313e-04 -2.436032e-04 -2.547445e-04 -2.663738e-04
## ASV0775     -3.950600e-04 -4.131252e-04 -4.319816e-04 -4.516604e-04
## ASV10911    -2.896992e-04 -3.029150e-04 -3.167070e-04 -3.310980e-04
## ASV1339     -4.926225e-05 -5.144350e-05 -5.371329e-05 -5.607445e-05
## ASV5214     -6.600388e-05 -6.894722e-05 -7.201223e-05 -7.520303e-05
## ASV4945      7.661359e-05  8.017301e-05  8.389312e-05  8.778069e-05
## ASV5624     -6.249920e-05 -6.514229e-05 -6.788112e-05 -7.071763e-05
## ASV3429     -3.566597e-05 -3.717785e-05 -3.874580e-05 -4.037124e-05
## ASV8416     -3.343468e-05 -3.521329e-05 -3.709249e-05 -3.907829e-05
## ASV2400     -3.573774e-04 -3.738113e-04 -3.909734e-04 -4.088935e-04
## ASV3388     -1.165473e-04 -1.220743e-04 -1.278615e-04 -1.339209e-04
## ASV7089      7.269589e-05  7.583946e-05  7.910376e-05  8.249199e-05
## ASV3396     -1.190934e-04 -1.244430e-04 -1.300174e-04 -1.358244e-04
## ASV0343      1.703700e-04  1.786648e-04  1.873693e-04  1.965041e-04
## ASV5505     -2.166264e-04 -2.267189e-04 -2.372711e-04 -2.483029e-04
## ASV6721     -1.022218e-04 -1.070776e-04 -1.121631e-04 -1.174890e-04
## ASV0537      8.921090e-05  9.387365e-05  9.879385e-05  1.039865e-04
## ASV7753     -2.809623e-04 -2.939443e-04 -3.075076e-04 -3.216763e-04
## ASV5022     -2.269384e-05 -2.398585e-05 -2.535729e-05 -2.681332e-05
## ASV1073      3.924964e-04  4.106473e-04  4.296120e-04  4.494248e-04
## ASV1347     -9.151817e-07 -1.009779e-06 -1.114266e-06 -1.229684e-06
## ASV15032     1.185935e-04  1.238627e-04  1.293478e-04  1.350559e-04
## ASV18213    -9.227939e-07 -1.018072e-06 -1.123298e-06 -1.239516e-06
## ASV20691     1.004366e-04  1.051447e-04  1.100693e-04  1.152196e-04
## ASV4260     -5.161412e-05 -5.401423e-05 -5.652396e-05 -5.914820e-05
## ASV4923      8.723170e-05  9.131316e-05  9.558135e-05  1.000444e-04
## ASV7995     -9.325754e-07 -1.028781e-06 -1.135021e-06 -1.252346e-06
## ASV8960      1.758380e-04  1.838853e-04  1.922849e-04  2.010507e-04
## ASV10682     1.334488e-04  1.392422e-04  1.452605e-04  1.515101e-04
## ASV11911    -9.511883e-07 -1.049088e-06 -1.157169e-06 -1.276496e-06
## ASV14296     2.114573e-04  2.209619e-04  2.308667e-04  2.411860e-04
## ASV2314      1.213290e-04  1.273444e-04  1.336661e-04  1.403099e-04
## ASV3819      1.364979e-04  1.426374e-04  1.490352e-04  1.557007e-04
## ASV4517     -9.794186e-07 -1.079962e-06 -1.190930e-06 -1.313407e-06
## ASV8941      2.611958e-04  2.733416e-04  2.860379e-04  2.993084e-04
## ASV1444      9.927711e-07  1.094576e-06  1.206921e-06  1.330903e-06
## ASV5959      4.762853e-05  4.977539e-05  5.201252e-05  5.434306e-05
## ASV3623     -1.205909e-04 -1.260341e-04 -1.317097e-04 -1.376267e-04
## ASV0260      1.455987e-04  1.523602e-04  1.594277e-04  1.668141e-04
## ASV4401     -9.642961e-05 -1.013114e-04 -1.064459e-04 -1.118462e-04
## ASV2891     -3.177653e-04 -3.325539e-04 -3.480146e-04 -3.641765e-04
## ASV2778     -7.149550e-05 -7.480565e-05 -7.826465e-05 -8.187877e-05
## ASV8744      1.398811e-04  1.460304e-04  1.524277e-04  1.590811e-04
## ASV1079      2.874283e-04  3.002592e-04  3.136250e-04  3.275447e-04
## ASV19688     2.178301e-05  2.297280e-05  2.423272e-05  2.556726e-05
## ASV4039      3.582584e-05  3.770157e-05  3.968168e-05  4.177239e-05
## ASV4982     -2.157723e-04 -2.256561e-04 -2.359746e-04 -2.467453e-04
## ASV1071     -2.157548e-04 -2.256369e-04 -2.359536e-04 -2.467223e-04
## ASV7666     -2.157372e-04 -2.256176e-04 -2.359325e-04 -2.466993e-04
## ASV0502      3.019311e-04  3.158710e-04  3.304337e-04  3.456453e-04
## ASV3624     -2.160703e-04 -2.259783e-04 -2.363228e-04 -2.471212e-04
## ASV0403      3.068610e-05  3.197457e-05  3.330925e-05  3.469108e-05
## ASV4939     -2.160507e-04 -2.259569e-04 -2.362994e-04 -2.470956e-04
## ASV6297     -2.588969e-04 -2.708952e-04 -2.834335e-04 -2.965349e-04
## ASV6343      2.302429e-04  2.402804e-04  2.507142e-04  2.615566e-04
## ASV0954     -4.847472e-05 -5.044429e-05 -5.247674e-05 -5.457233e-05
## ASV10225    -9.430660e-05 -9.876981e-05 -1.034410e-04 -1.083294e-04
## ASV1584      3.756906e-04  3.929221e-04  4.109129e-04  4.296937e-04
## ASV1803      1.377818e-04  1.438500e-04  1.501619e-04  1.567250e-04
## ASV2576     -3.756515e-04 -3.928793e-04 -4.108661e-04 -4.296426e-04
## ASV3252      2.443991e-04  2.557028e-04  2.675131e-04  2.798513e-04
## ASV3463     -3.756192e-04 -3.928440e-04 -4.108276e-04 -4.296005e-04
## ASV3822     -2.857919e-04 -2.991185e-04 -3.130534e-04 -3.276233e-04
## ASV4926     -1.515374e-04 -1.581284e-04 -1.649769e-04 -1.720904e-04
## ASV5564     -9.709935e-05 -1.015583e-04 -1.062146e-04 -1.110762e-04
## ASV5595     -5.666227e-05 -5.924936e-05 -6.194970e-05 -6.476783e-05
## ASV16463    -2.189692e-04 -2.291535e-04 -2.398001e-04 -2.509291e-04
## ASV6277      2.188908e-04  2.291974e-04  2.399823e-04  2.512669e-04
## ASV1344      2.189607e-04  2.291442e-04  2.397899e-04  2.509180e-04
## ASV1869      1.394956e-04  1.456687e-04  1.520927e-04  1.587755e-04
## ASV8155     -1.195669e-04 -1.248181e-04 -1.302792e-04 -1.359569e-04
## ASV2502     -2.210039e-04 -2.310957e-04 -2.416280e-04 -2.526182e-04
## ASV6742     -6.879921e-05 -7.172707e-05 -7.476337e-05 -7.791065e-05
## ASV3124     -1.435177e-04 -1.500612e-04 -1.568912e-04 -1.640192e-04
## ASV17042    -2.513536e-04 -2.628699e-04 -2.748925e-04 -2.874417e-04
## ASV0248      3.483838e-04  3.641986e-04  3.806961e-04  3.979025e-04
## ASV4557      5.953031e-05  6.262109e-05  6.587929e-05  6.931425e-05
## ASV3507     -3.822717e-04 -4.000041e-04 -4.185366e-04 -4.379032e-04
## ASV1870      2.808131e-05  2.937694e-05  3.073034e-05  3.214389e-05
## ASV2447     -1.842663e-04 -1.929097e-04 -2.019529e-04 -2.114137e-04
## ASV0347      2.991280e-04  3.130902e-04  3.276910e-04  3.429583e-04
## ASV1855     -1.372192e-04 -1.435831e-04 -1.502342e-04 -1.571848e-04
## ASV0568      1.030752e-04  1.077701e-04  1.126691e-04  1.177803e-04
## ASV1620     -1.836777e-04 -1.921530e-04 -2.010064e-04 -2.102534e-04
## ASV0101     -1.481351e-04 -1.545167e-04 -1.611427e-04 -1.680197e-04
## ASV7751      1.385375e-04  1.452494e-04  1.522907e-04  1.596780e-04
## ASV9033     -2.513462e-04 -2.630270e-04 -2.752370e-04 -2.879990e-04
## ASV3438     -7.293228e-05 -7.637146e-05 -7.997130e-05 -8.373916e-05
## ASV0637     -2.346366e-04 -2.454558e-04 -2.567569e-04 -2.685601e-04
## ASV1181     -1.734726e-04 -1.815435e-04 -1.899806e-04 -1.987995e-04
## ASV13480    -2.184439e-04 -2.285738e-04 -2.391604e-04 -2.502230e-04
## ASV14220    -2.184259e-04 -2.285541e-04 -2.391388e-04 -2.501993e-04
## ASV1448     -1.596051e-04 -1.670529e-04 -1.748409e-04 -1.829839e-04
## ASV1457      1.467128e-04  1.532518e-04  1.600611e-04  1.671501e-04
## ASV1645      1.059462e-04  1.109487e-04  1.161849e-04  1.216653e-04
## ASV2300     -1.421231e-04 -1.485822e-04 -1.553200e-04 -1.623473e-04
## ASV2533      2.187140e-04  2.286281e-04  2.389679e-04  2.497497e-04
## ASV5059      5.367872e-05  5.592586e-05  5.825259e-05  6.066041e-05
## ASV8871     -2.184187e-04 -2.285461e-04 -2.391299e-04 -2.501896e-04
## ASV1289     -2.337633e-04 -2.444141e-04 -2.555280e-04 -2.671230e-04
## ASV3983     -9.975073e-05 -1.044539e-04 -1.093762e-04 -1.145275e-04
## ASV10323    -7.924720e-05 -8.313017e-05 -8.720716e-05 -9.148806e-05
## ASV13279    -2.183726e-04 -2.284957e-04 -2.390747e-04 -2.501291e-04
## ASV7149     -2.183546e-04 -2.284760e-04 -2.390532e-04 -2.501055e-04
## ASV1691      4.167195e-05  4.365288e-05  4.572818e-05  4.790238e-05
## ASV1649      1.073824e-04  1.124102e-04  1.176679e-04  1.231653e-04
## ASV10120     3.161457e-05  3.314430e-05  3.474903e-05  3.643253e-05
## ASV8285     -2.787051e-04 -2.918473e-04 -3.056009e-04 -3.199934e-04
## ASV0037     -2.395787e-04 -2.507989e-04 -2.625353e-04 -2.748107e-04
## ASV1770      6.256696e-05  6.545615e-05  6.847492e-05  7.162875e-05
## ASV2252      5.985308e-05  6.261042e-05  6.549011e-05  6.849713e-05
## ASV7580      2.416702e-04  2.525012e-04  2.637865e-04  2.755422e-04
## ASV5643     -2.209828e-04 -2.311989e-04 -2.418730e-04 -2.530243e-04
## ASV2722     -7.112626e-05 -7.460357e-05 -7.825459e-05 -8.208828e-05
## ASV2662     -1.516499e-04 -1.587074e-04 -1.660861e-04 -1.738002e-04
## ASV0479     -3.457647e-04 -3.614911e-04 -3.778991e-04 -3.950151e-04
## ASV2009     -3.638335e-04 -3.801542e-04 -3.971603e-04 -4.148764e-04
## ASV3731     -2.452561e-04 -2.563612e-04 -2.679424e-04 -2.800177e-04
## ASV5497     -3.035320e-04 -3.174331e-04 -3.319452e-04 -3.470930e-04
## ASV6647      1.332071e-05  1.380352e-05  1.429522e-05  1.479493e-05
## ASV8974     -2.236851e-04 -2.338757e-04 -2.445088e-04 -2.556018e-04
## ASV15527     1.954098e-05  2.037728e-05  2.124509e-05  2.214522e-05
## ASV6705     -1.382285e-04 -1.450432e-04 -1.522025e-04 -1.597245e-04
## ASV0354      2.861897e-04  2.994157e-04  3.132340e-04  3.276693e-04
## ASV2707      6.527255e-05  6.808551e-05  7.100577e-05  7.403613e-05
## ASV11167    -3.759879e-04 -3.932548e-04 -4.112843e-04 -4.301072e-04
## ASV6393     -2.992156e-04 -3.130052e-04 -3.274086e-04 -3.424510e-04
## ASV3808     -2.132275e-04 -2.228192e-04 -2.328175e-04 -2.432375e-04
## ASV9337      2.943479e-05  3.060893e-05  3.181798e-05  3.306174e-05
## ASV5043     -3.069538e-04 -3.210917e-04 -3.358581e-04 -3.512788e-04
## ASV4189     -8.786702e-06 -9.030161e-06 -9.269400e-06 -9.502847e-06
## ASV1304     -1.165595e-04 -1.215124e-04 -1.266487e-04 -1.319728e-04
## ASV2105     -1.608876e-04 -1.683207e-04 -1.760867e-04 -1.841995e-04
## ASV2421     -5.601614e-05 -5.866703e-05 -6.144284e-05 -6.434943e-05
## ASV3170      2.572533e-04  2.692622e-04  2.818203e-04  2.949517e-04
## ASV5036      3.444923e-04  3.603282e-04  3.768655e-04  3.941328e-04
## ASV2286      2.173529e-04  2.273844e-04  2.378641e-04  2.488107e-04
## ASV3363      2.175398e-04  2.277976e-04  2.385337e-04  2.497700e-04
## ASV5759     -2.007216e-05 -2.108032e-05 -2.214154e-05 -2.325881e-05
## ASV5440     -1.507293e-04 -1.579466e-04 -1.655101e-04 -1.734363e-04
## ASV2050      2.495358e-04  2.605865e-04  2.720865e-04  2.840505e-04
## ASV4478      1.781872e-04  1.866269e-04  1.954636e-04  2.047155e-04
## ASV5725     -1.917497e-04 -2.004565e-04 -2.095393e-04 -2.190126e-04
## ASV1600     -5.570025e-05 -5.871135e-05 -6.189650e-05 -6.526636e-05
## ASV1654     -3.414023e-04 -3.569365e-04 -3.731445e-04 -3.900526e-04
## ASV3781     -1.472239e-04 -1.538127e-04 -1.606767e-04 -1.678255e-04
## ASV7144     -1.264204e-04 -1.320465e-04 -1.379043e-04 -1.440017e-04
## ASV12710    -4.639870e-05 -4.823623e-05 -5.012793e-05 -5.207354e-05
## ASV3317      1.721806e-04  1.800815e-04  1.883319e-04  1.969464e-04
## ASV3249     -3.372290e-04 -3.527164e-04 -3.688879e-04 -3.857713e-04
## ASV0669     -2.101025e-04 -2.194774e-04 -2.292418e-04 -2.394094e-04
## ASV0893      1.243298e-04  1.299900e-04  1.358958e-04  1.420568e-04
## ASV11060    -1.243197e-04 -1.299790e-04 -1.358838e-04 -1.420436e-04
## ASV3207      4.292463e-04  4.494193e-04  4.705266e-04  4.926100e-04
## ASV3498     -1.243184e-04 -1.299776e-04 -1.358823e-04 -1.420420e-04
## ASV4358      7.882095e-05  8.243304e-05  8.620394e-05  9.014001e-05
## ASV4806      2.135136e-04  2.233145e-04  2.335477e-04  2.442305e-04
## ASV4941      1.243129e-04  1.299716e-04  1.358757e-04  1.420348e-04
## ASV6998      3.726053e-05  3.896852e-05  4.075139e-05  4.261209e-05
## ASV7327     -1.243051e-04 -1.299631e-04 -1.358665e-04 -1.420247e-04
## ASV5112      2.515255e-04  2.632436e-04  2.754942e-04  2.883003e-04
## ASV5345     -1.242867e-04 -1.299429e-04 -1.358443e-04 -1.420005e-04
## ASV8911     -1.242766e-04 -1.299319e-04 -1.358323e-04 -1.419873e-04
## ASV5061      2.904980e-04  3.038211e-04  3.177309e-04  3.322511e-04
## ASV1968     -2.567790e-05 -2.698857e-05 -2.836943e-05 -2.982447e-05
## ASV4669     -1.242579e-04 -1.299115e-04 -1.358100e-04 -1.419630e-04
## ASV6209     -4.589020e-05 -4.783750e-05 -4.985580e-05 -5.194658e-05
## ASV6938      2.469355e-04  2.581106e-04  2.697638e-04  2.819132e-04
## ASV6987      1.370505e-04  1.430816e-04  1.493550e-04  1.558783e-04
## ASV7842     -1.242529e-04 -1.299061e-04 -1.358041e-04 -1.419566e-04
## ASV17950     8.153309e-08  8.813670e-08  9.520396e-08  1.027570e-07
## ASV3380     -3.618455e-04 -3.781804e-04 -3.952112e-04 -4.129641e-04
## ASV13740    -3.088607e-04 -3.231985e-04 -3.381844e-04 -3.538461e-04
## ASV4313     -1.811592e-04 -1.895350e-04 -1.982859e-04 -2.074277e-04
## ASV3891     -1.876085e-04 -1.957096e-04 -2.041231e-04 -2.128576e-04
## ASV3322     -2.191970e-04 -2.292979e-04 -2.398488e-04 -2.508683e-04
## ASV1668     -3.787285e-05 -3.970659e-05 -4.163114e-05 -4.365124e-05
## ASV1739      8.454008e-05  8.823408e-05  9.207405e-05  9.606436e-05
## ASV3194      1.746149e-04  1.826225e-04  1.909831e-04  1.997109e-04
## ASV0071     -2.621748e-04 -2.735579e-04 -2.853855e-04 -2.976706e-04
## ASV0695      1.268568e-04  1.328130e-04  1.390425e-04  1.455569e-04
## ASV3835     -9.901417e-05 -1.034588e-04 -1.080905e-04 -1.129158e-04
## ASV1876      1.025190e-04  1.073249e-04  1.123518e-04  1.176096e-04
## ASV4892     -3.041991e-04 -3.182626e-04 -3.329562e-04 -3.483066e-04
## ASV1212     -1.047508e-04 -1.095465e-04 -1.145532e-04 -1.197795e-04
## ASV2640      1.371752e-06  1.378158e-06  1.379685e-06  1.375668e-06
## ASV7236     -3.008216e-04 -3.148031e-04 -3.294182e-04 -3.446940e-04
## ASV2353     -8.430709e-05 -8.834323e-05 -9.257319e-05 -9.700631e-05
## ASV0276      3.650089e-04  3.812272e-04  3.981145e-04  4.156941e-04
## ASV2262     -1.114148e-04 -1.165343e-04 -1.218813e-04 -1.274654e-04
## ASV11201    -7.476945e-05 -7.833220e-05 -8.206425e-05 -8.597357e-05
## ASV0665      3.001667e-05  3.135114e-05  3.274116e-05  3.418876e-05
## ASV5238      2.968563e-05  3.054292e-05  3.139204e-05  3.222855e-05
## ASV6885     -1.650379e-04 -1.725776e-04 -1.804471e-04 -1.886594e-04
## ASV1844      6.749533e-05  7.089927e-05  7.448154e-05  7.825188e-05
## ASV0379      2.152622e-04  2.250949e-04  2.353572e-04  2.460660e-04
## ASV1040     -6.716210e-05 -7.009331e-05 -7.314028e-05 -7.630650e-05
## ASV7913     -1.249481e-04 -1.306950e-04 -1.366964e-04 -1.429628e-04
## ASV1197     -2.152307e-04 -2.250605e-04 -2.353195e-04 -2.460249e-04
## ASV5918      9.332830e-05  9.765524e-05  1.021774e-04  1.069030e-04
## ASV8045      4.856595e-05  5.099307e-05  5.354502e-05  5.622839e-05
## ASV16458    -2.134418e-05 -2.216342e-05 -2.300386e-05 -2.386497e-05
## ASV10827    -2.152181e-04 -2.250468e-04 -2.353046e-04 -2.460087e-04
## ASV3658     -2.152006e-04 -2.250277e-04 -2.352837e-04 -2.459858e-04
## ASV0073     -4.468692e-04 -4.676017e-04 -4.892693e-04 -5.119115e-04
## ASV1951     -9.086056e-05 -9.543210e-05 -1.002416e-04 -1.053017e-04
## ASV7630     -2.840503e-04 -2.970869e-04 -3.106988e-04 -3.249093e-04
## ASV9449     -1.518777e-04 -1.590650e-04 -1.665890e-04 -1.744651e-04
## ASV3944      3.048916e-04  3.188404e-04  3.334016e-04  3.485999e-04
## ASV1520     -4.122983e-04 -4.310644e-04 -4.506440e-04 -4.710686e-04
## ASV0307      3.192887e-04  3.341819e-04  3.497548e-04  3.660371e-04
## ASV12731    -8.116024e-05 -8.504563e-05 -8.911784e-05 -9.338591e-05
## ASV0282      3.205679e-04  3.355201e-04  3.511548e-04  3.675016e-04
## ASV2646      2.864596e-04  2.991859e-04  3.124354e-04  3.262256e-04
## ASV3536      2.283468e-04  2.388642e-04  2.498491e-04  2.613206e-04
## ASV10089    -2.096780e-04 -2.189930e-04 -2.286910e-04 -2.387850e-04
## ASV1185      2.096614e-04  2.189749e-04  2.286713e-04  2.387635e-04
## ASV1452      2.096448e-04  2.189569e-04  2.286516e-04  2.387421e-04
## ASV1700      2.096282e-04  2.189388e-04  2.286319e-04  2.387206e-04
## ASV6948     -2.096117e-04 -2.189207e-04 -2.286122e-04 -2.386991e-04
## ASV0389     -2.737253e-04 -2.859661e-04 -2.987175e-04 -3.119974e-04
## ASV11884     2.933775e-06  3.374165e-06  3.861198e-06  4.399101e-06
## ASV23165    -2.095755e-04 -2.188813e-04 -2.285692e-04 -2.386523e-04
## ASV2841      2.095589e-04  2.188632e-04  2.285496e-04  2.386309e-04
## ASV2949      2.095423e-04  2.188452e-04  2.285299e-04  2.386094e-04
## ASV4037      2.095258e-04  2.188271e-04  2.285102e-04  2.385879e-04
## ASV4477      2.095092e-04  2.188090e-04  2.284905e-04  2.385665e-04
## ASV4496      2.094927e-04  2.187910e-04  2.284708e-04  2.385450e-04
## ASV5784     -2.094761e-04 -2.187729e-04 -2.284511e-04 -2.385236e-04
## ASV6035      5.614743e-06  6.070210e-06  6.563608e-06  7.098034e-06
## ASV6232     -2.098352e-04 -2.191478e-04 -2.288424e-04 -2.389320e-04
## ASV1818      2.094436e-04  2.187375e-04  2.284126e-04  2.384816e-04
## ASV2595      2.094271e-04  2.187195e-04  2.283929e-04  2.384602e-04
## ASV2788     -2.751845e-05 -2.875480e-05 -3.004309e-05 -3.138515e-05
## ASV5018      2.094120e-04  2.187030e-04  2.283749e-04  2.384406e-04
## ASV0127      2.847183e-04  2.979789e-04  3.118428e-04  3.263363e-04
## ASV1527      6.785642e-06  7.183961e-06  7.607542e-06  8.058062e-06
## ASV1055      1.613784e-04  1.687767e-04  1.765004e-04  1.845626e-04
## ASV4791      1.029554e-04  1.070290e-04  1.112234e-04  1.155384e-04
## ASV0859      1.152164e-04  1.204082e-04  1.258195e-04  1.314583e-04
## ASV12971    -3.077462e-04 -3.219318e-04 -3.367488e-04 -3.522231e-04
## ASV16856    -3.077210e-04 -3.219042e-04 -3.367186e-04 -3.521900e-04
## ASV7321     -2.514318e-04 -2.630403e-04 -2.751672e-04 -2.878339e-04
## ASV8780     -3.076756e-04 -3.218546e-04 -3.366642e-04 -3.521306e-04
## ASV1569      2.253539e-04  2.356835e-04  2.464678e-04  2.577252e-04
## ASV3696      3.620413e-05  3.779187e-05  3.944261e-05  4.115823e-05
## ASV0624      4.122908e-04  4.311375e-04  4.508108e-04  4.713437e-04
## ASV0495      2.511391e-04  2.624632e-04  2.742684e-04  2.865723e-04
## ASV16971    -1.256833e-04 -1.314698e-04 -1.375133e-04 -1.438244e-04
## ASV6535      7.186608e-05  7.535739e-05  7.902077e-05  8.286486e-05
## ASV1897      2.947739e-04  3.081077e-04  3.220124e-04  3.365095e-04
## ASV2631     -3.849426e-05 -4.051694e-05 -4.265276e-05 -4.490853e-05
## ASV6204      9.919791e-05  1.038343e-04  1.086827e-04  1.137523e-04
## ASV3312     -1.896987e-04 -1.984751e-04 -2.076459e-04 -2.172278e-04
## ASV3360      1.203480e-04  1.260421e-04  1.320030e-04  1.382430e-04
## ASV3907      5.851653e-05  6.131621e-05  6.424979e-05  6.732361e-05
## ASV6090      6.008524e-05  6.287418e-05  6.578855e-05  6.883358e-05
## ASV8652     -6.894675e-05 -7.198216e-05 -7.513975e-05 -7.842338e-05
## ASV11129    -1.242785e-04 -1.299375e-04 -1.358424e-04 -1.420029e-04
## ASV11073    -1.242684e-04 -1.299264e-04 -1.358303e-04 -1.419897e-04
## ASV1840      4.158979e-04  4.347768e-04  4.544691e-04  4.750057e-04
## ASV2298      1.568312e-04  1.638715e-04  1.712086e-04  1.788533e-04
## ASV2420      3.730912e-04  3.903062e-04  4.082898e-04  4.270738e-04
## ASV6474      5.116589e-05  5.361374e-05  5.617830e-05  5.886502e-05
## ASV8475     -1.242550e-04 -1.299118e-04 -1.358144e-04 -1.419723e-04
## ASV8679     -1.242449e-04 -1.299008e-04 -1.358023e-04 -1.419591e-04
## ASV6527      1.186768e-04  1.242344e-04  1.300478e-04  1.361283e-04
## ASV2504     -2.004183e-05 -2.112087e-05 -2.226215e-05 -2.346949e-05
## ASV1093     -1.320069e-04 -1.380632e-04 -1.443863e-04 -1.509867e-04
## ASV0994      1.739048e-04  1.819204e-04  1.902929e-04  1.990372e-04
## ASV0092     -2.872395e-04 -3.007009e-04 -3.147822e-04 -3.295111e-04
## ASV2619      6.523701e-05  6.830239e-05  7.150947e-05  7.486454e-05
## ASV0121      3.615989e-04  3.775606e-04  3.941689e-04  4.114451e-04
## ASV0932      1.251544e-04  1.311079e-04  1.373428e-04  1.438723e-04
## ASV5229      2.080995e-04  2.175015e-04  2.273043e-04  2.375228e-04
## ASV6737      2.125968e-04  2.224304e-04  2.327048e-04  2.434386e-04
## ASV11213    -2.989830e-04 -3.123540e-04 -3.262828e-04 -3.407889e-04
## ASV1151      6.181024e-04  6.464590e-04  6.760659e-04  7.069736e-04
## ASV3813      3.222481e-04  3.367438e-04  3.518518e-04  3.675944e-04
## ASV5566      6.776522e-05  7.130057e-05  7.503131e-05  7.896893e-05
## ASV7529     -2.989467e-04 -3.123145e-04 -3.262398e-04 -3.407420e-04
## ASV2193      4.329164e-04  4.530816e-04  4.741644e-04  4.962045e-04
## ASV2349      3.976812e-04  4.160362e-04  4.352116e-04  4.552417e-04
## ASV2387      3.479992e-04  3.635098e-04  3.796624e-04  3.964792e-04
## ASV2699      2.912608e-04  3.049939e-04  3.193675e-04  3.344109e-04
## ASV3353      3.787601e-04  3.960201e-04  4.140301e-04  4.328193e-04
## ASV3621      2.012193e-04  2.101630e-04  2.194745e-04  2.291665e-04
## ASV3848      3.598797e-05  3.771536e-05  3.952605e-05  4.142407e-05
## ASV4440      5.309432e-06  5.825202e-06  6.388698e-06  7.004097e-06
## ASV4751      3.998081e-04  4.182603e-04  4.375366e-04  4.576714e-04
## ASV5115      1.715569e-04  1.795802e-04  1.879711e-04  1.967455e-04
## ASV5850     -2.988837e-04 -3.122457e-04 -3.261647e-04 -3.406602e-04
## ASV6293      1.854308e-04  1.939711e-04  2.028910e-04  2.122060e-04
## ASV6513      8.222879e-05  8.629018e-05  9.055756e-05  9.504175e-05
## ASV7628     -2.988642e-04 -3.122245e-04 -3.261415e-04 -3.406349e-04
## ASV7658      1.835404e-04  1.921399e-04  2.011342e-04  2.105405e-04
## ASV0776     -3.519231e-04 -3.677811e-04 -3.843113e-04 -4.015383e-04
## ASV10227    -2.988429e-04 -3.122013e-04 -3.261162e-04 -3.406073e-04
## ASV11965    -2.988191e-04 -3.121753e-04 -3.260879e-04 -3.405765e-04
## ASV1270     -1.008446e-04 -1.052270e-04 -1.097800e-04 -1.145085e-04
## ASV13123    -2.254640e-04 -2.354669e-04 -2.458797e-04 -2.567159e-04
## ASV5828      2.987725e-04  3.121244e-04  3.260324e-04  3.405160e-04
## ASV5920     -2.987487e-04 -3.120985e-04 -3.260041e-04 -3.404852e-04
## ASV6071      2.851447e-04  2.984108e-04  3.122796e-04  3.267769e-04
## ASV6723     -1.384333e-05 -1.429574e-05 -1.475151e-05 -1.520933e-05
## ASV6727     -2.987188e-04 -3.120659e-04 -3.259686e-04 -3.404463e-04
## ASV7759     -2.986950e-04 -3.120399e-04 -3.259403e-04 -3.404155e-04
## ASV0733      2.123990e-05  2.227260e-05  2.335686e-05  2.449540e-05
## ASV1655     -4.598186e-05 -4.835757e-05 -5.086281e-05 -5.350511e-05
## ASV0755     -4.451319e-04 -4.652449e-04 -4.862168e-04 -5.080797e-04
## ASV0796      1.803373e-04  1.880951e-04  1.961484e-04  2.045049e-04
## ASV0878      3.865071e-04  4.042192e-04  4.227105e-04  4.420121e-04
## ASV4988     -2.399690e-04 -2.509828e-04 -2.624825e-04 -2.744877e-04
## ASV0083     -2.744089e-04 -2.872067e-04 -3.005868e-04 -3.145742e-04
## ASV0273      1.280534e-04  1.335468e-04  1.392494e-04  1.451668e-04
## ASV3076      9.036367e-05  9.461187e-05  9.905692e-05  1.037077e-04
## ASV1513      7.387459e-05  7.722389e-05  8.071703e-05  8.435945e-05
## ASV5159     -1.836242e-05 -1.907276e-05 -1.980256e-05 -2.055160e-05
## ASV3422     -1.828211e-04 -1.913135e-04 -2.001904e-04 -2.094683e-04
## ASV12230    -2.582776e-05 -2.690591e-05 -2.802172e-05 -2.917580e-05
## ASV1694      3.768618e-04  3.938219e-04  4.115013e-04  4.299266e-04
## ASV1249      1.656124e-04  1.732499e-04  1.812275e-04  1.895593e-04
## ASV1697     -9.126324e-05 -9.537258e-05 -9.965610e-05 -1.041202e-04
## ASV4408     -2.226537e-04 -2.322429e-04 -2.422004e-04 -2.525366e-04
## ASV0095     -2.833836e-04 -2.967353e-04 -3.107085e-04 -3.253313e-04
## ASV0410      5.632164e-07  4.172285e-07  2.485695e-07  5.478846e-08
## ASV4642     -3.534144e-04 -3.697340e-04 -3.867830e-04 -4.045917e-04
## ASV4560     -1.008669e-06 -8.684571e-07 -7.046617e-07 -5.147125e-07
## ASV7586     -1.665856e-04 -1.743171e-04 -1.823976e-04 -1.908418e-04
## ASV4144     -1.875932e-04 -1.963619e-04 -2.055322e-04 -2.151218e-04
## ASV0327     -2.028227e-04 -2.120737e-04 -2.217275e-04 -2.318002e-04
## ASV0946     -1.702201e-04 -1.776241e-04 -1.853191e-04 -1.933139e-04
## ASV3254     -2.197206e-04 -2.299699e-04 -2.406868e-04 -2.518916e-04
## ASV0349      3.169863e-04  3.316492e-04  3.469695e-04  3.629748e-04
## ASV0472     -1.929583e-04 -2.017643e-04 -2.109540e-04 -2.205427e-04
## ASV1330      1.936226e-04  2.021771e-04  2.110785e-04  2.203379e-04
## ASV2605      2.064976e-04  2.160515e-04  2.260338e-04  2.364624e-04
## ASV2846     -1.183764e-04 -1.240363e-04 -1.299666e-04 -1.361804e-04
## ASV3982     -9.625340e-05 -1.007971e-04 -1.055531e-04 -1.105312e-04
## ASV4116     -2.196885e-04 -2.299347e-04 -2.406482e-04 -2.518493e-04
## ASV6048     -1.287070e-04 -1.347423e-04 -1.410557e-04 -1.476598e-04
## ASV1146      2.647260e-04  2.768683e-04  2.895453e-04  3.027784e-04
## ASV13362     1.527905e-05  1.589074e-05  1.652108e-05  1.717004e-05
## ASV1422     -2.196647e-04 -2.299086e-04 -2.406196e-04 -2.518179e-04
## ASV3640     -2.196465e-04 -2.298887e-04 -2.405977e-04 -2.517939e-04
## ASV5404      1.712517e-04  1.788493e-04  1.867586e-04  1.949903e-04
## ASV6118     -2.196343e-04 -2.298752e-04 -2.405830e-04 -2.517777e-04
## ASV1115     -1.874809e-04 -1.962255e-04 -2.053684e-04 -2.149269e-04
## ASV0888     -4.008622e-04 -4.193104e-04 -4.385776e-04 -4.586973e-04
## ASV4620      5.094057e-05  5.261312e-05  5.429988e-05  5.599625e-05
## ASV3099      7.919073e-05  8.300829e-05  8.701118e-05  9.120843e-05
## ASV7099      3.682481e-05  3.861385e-05  4.049092e-05  4.246040e-05
## ASV5892     -2.524320e-04 -2.640774e-04 -2.762422e-04 -2.889480e-04
## ASV6978     -2.515890e-04 -2.633136e-04 -2.755725e-04 -2.883889e-04
## ASV6555     -8.631179e-05 -9.076407e-05 -9.545797e-05 -1.004074e-04
## ASV0539     -3.164880e-04 -3.309016e-04 -3.459410e-04 -3.616306e-04
## ASV4665      8.822985e-05  9.199869e-05  9.590831e-05  9.996215e-05
## ASV2210      1.897358e-04  1.979550e-04  2.064959e-04  2.153683e-04
## ASV1329      2.004952e-04  2.098538e-04  2.196395e-04  2.298707e-04
## ASV7123     -2.909402e-04 -3.044870e-04 -3.186503e-04 -3.334567e-04
## ASV1260      1.975609e-06  2.108432e-06  2.250976e-06  2.403980e-06
## ASV1011      2.974450e-04  3.115183e-04  3.262516e-04  3.416752e-04
## ASV4233      8.133426e-05  8.517344e-05  8.919194e-05  9.339793e-05
## ASV1475      3.014639e-04  3.151963e-04  3.295268e-04  3.444791e-04
## ASV6099     -3.490897e-04 -3.649989e-04 -3.815997e-04 -3.989194e-04
## ASV1428      3.082865e-06  3.980597e-06  4.987127e-06  6.113078e-06
## ASV5101     -3.837903e-04 -4.017940e-04 -4.206295e-04 -4.403339e-04
## ASV11827    -1.729008e-04 -1.808978e-04 -1.892534e-04 -1.979828e-04
## ASV13899    -1.965929e-04 -2.056793e-04 -2.151726e-04 -2.250898e-04
## ASV21259    -2.309240e-04 -2.416531e-04 -2.528681e-04 -2.645898e-04
## ASV6635     -1.143411e-04 -1.197620e-04 -1.254385e-04 -1.313824e-04
## ASV9922     -3.094769e-04 -3.238296e-04 -3.388297e-04 -3.545047e-04
## ASV2869      3.795056e-05  3.964455e-05  4.140849e-05  4.324472e-05
## ASV1740      2.017572e-04  2.109387e-04  2.205182e-04  2.305109e-04
## ASV4406     -3.120653e-04 -3.266656e-04 -3.419367e-04 -3.579082e-04
## ASV5586     -2.662782e-04 -2.788308e-04 -2.919688e-04 -3.057187e-04
## ASV3255     -1.054147e-04 -1.102409e-04 -1.152791e-04 -1.205378e-04
## ASV12281    -1.477345e-04 -1.543880e-04 -1.613240e-04 -1.685532e-04
## ASV5388     -2.910013e-04 -3.039888e-04 -3.175155e-04 -3.316002e-04
## ASV17660    -2.996603e-04 -3.135149e-04 -3.279906e-04 -3.431136e-04
## ASV0159      1.644496e-04  1.717314e-04  1.793132e-04  1.872058e-04
## ASV2734     -4.440054e-04 -4.643518e-04 -4.855935e-04 -5.077665e-04
## ASV2049      3.380387e-05  3.537221e-05  3.701166e-05  3.872533e-05
## ASV2465      2.095579e-05  2.159344e-05  2.223031e-05  2.286386e-05
## ASV2147      1.371226e-04  1.428576e-04  1.487962e-04  1.549423e-04
## ASV3113     -4.274168e-05 -4.466677e-05 -4.667283e-05 -4.876270e-05
## ASV0622     -3.150939e-04 -3.297247e-04 -3.450162e-04 -3.609964e-04
## ASV0437     -3.156412e-04 -3.301157e-04 -3.452278e-04 -3.610030e-04
## ASV6385     -3.454444e-04 -3.614439e-04 -3.781629e-04 -3.956318e-04
## ASV3699     -3.137975e-04 -3.285607e-04 -3.440096e-04 -3.601754e-04
## ASV2208      3.137713e-04  3.285319e-04  3.439781e-04  3.601409e-04
## ASV1053      7.156961e-05  7.485428e-05  7.828433e-05  8.186572e-05
## ASV8468     -6.998984e-05 -7.313288e-05 -7.640822e-05 -7.982063e-05
## ASV0951     -2.626844e-04 -2.746711e-04 -2.871807e-04 -3.002338e-04
## ASV0278      3.752796e-04  3.921677e-04  4.097703e-04  4.281137e-04
## ASV0914     -1.965518e-04 -2.055547e-04 -2.149529e-04 -2.247622e-04
## ASV0737      2.926272e-04  3.054243e-04  3.187296e-04  3.325588e-04
## ASV2038      4.235467e-04  4.426898e-04  4.626507e-04  4.834603e-04
## ASV2171      2.567268e-04  2.678737e-04  2.794558e-04  2.914856e-04
## ASV2607      2.925739e-04  3.053662e-04  3.186664e-04  3.324899e-04
## ASV3143      2.219357e-04  2.314944e-04  2.414190e-04  2.517194e-04
## ASV3187     -3.139546e-04 -3.277190e-04 -3.420334e-04 -3.569150e-04
## ASV3810      2.925105e-04  3.052972e-04  3.185912e-04  3.324081e-04
## ASV5060     -1.798605e-04 -1.875798e-04 -1.955921e-04 -2.039051e-04
## ASV5325      2.924752e-04  3.052588e-04  3.185494e-04  3.323627e-04
## ASV6905     -2.924524e-04 -3.052340e-04 -3.185224e-04 -3.323333e-04
## ASV7597     -2.924297e-04 -3.052092e-04 -3.184955e-04 -3.323040e-04
## ASV9652     -2.924070e-04 -3.051845e-04 -3.184685e-04 -3.322747e-04
## ASV2634      2.923842e-04  3.051597e-04  3.184416e-04  3.322454e-04
## ASV3065      2.923615e-04  3.051350e-04  3.184147e-04  3.322161e-04
## ASV3331      2.923388e-04  3.051102e-04  3.183877e-04  3.321868e-04
## ASV7434     -2.923161e-04 -3.050855e-04 -3.183608e-04 -3.321575e-04
## ASV7720      4.767597e-05  5.033993e-05  5.316440e-05  5.615965e-05
## ASV8414     -2.922956e-04 -3.050633e-04 -3.183367e-04 -3.321313e-04
## ASV12139    -2.922729e-04 -3.050386e-04 -3.183098e-04 -3.321020e-04
## ASV1824      2.847946e-04  2.972164e-04  3.101285e-04  3.235458e-04
## ASV2094      2.885679e-04  3.011670e-04  3.142647e-04  3.278762e-04
## ASV2770     -6.705610e-05 -7.046713e-05 -7.405846e-05 -7.783995e-05
## ASV3505     -1.406079e-04 -1.463552e-04 -1.522925e-04 -1.584219e-04
## ASV1935      2.921994e-04  3.049587e-04  3.182229e-04  3.320076e-04
## ASV5764     -2.921767e-04 -3.049340e-04 -3.181960e-04 -3.319784e-04
## ASV6806      1.872637e-04  1.961068e-04  2.053630e-04  2.150508e-04
## ASV6942     -2.921557e-04 -3.049110e-04 -3.181711e-04 -3.319512e-04
## ASV1166      3.211811e-04  3.352833e-04  3.499509e-04  3.652019e-04
## ASV1664      2.285158e-04  2.387385e-04  2.493878e-04  2.604785e-04
## ASV2568      2.921118e-04  3.048633e-04  3.181191e-04  3.318947e-04
## ASV3525      2.920892e-04  3.048386e-04  3.180922e-04  3.318654e-04
## ASV4965     -3.499571e-04 -3.656108e-04 -3.819186e-04 -3.989039e-04
## ASV6607     -1.803621e-04 -1.879287e-04 -1.957655e-04 -2.038778e-04
## ASV7187      9.918722e-05  1.036764e-04  1.083574e-04  1.132371e-04
## ASV0388     -2.903483e-04 -3.040889e-04 -3.184748e-04 -3.335358e-04
## ASV1420      2.019304e-06  2.205302e-06  2.407906e-06  2.628528e-06
## ASV14293     9.438104e-05  9.894808e-05  1.037385e-04  1.087634e-04
## ASV17785     2.011610e-06  2.196833e-06  2.398586e-06  2.618268e-06
## ASV7678      1.777269e-05  1.815887e-05  1.852330e-05  1.886167e-05
## ASV2253      7.962693e-05  8.347025e-05  8.750053e-05  9.172693e-05
## ASV4150      1.593754e-04  1.664413e-04  1.737971e-04  1.814524e-04
## ASV3836     -3.688273e-04 -3.857316e-04 -4.033803e-04 -4.218035e-04
## ASV16231    -3.027502e-04 -3.169073e-04 -3.317141e-04 -3.471993e-04
## ASV2730      6.105486e-06  6.390151e-06  6.688047e-06  6.999806e-06
## ASV2072      1.715401e-04  1.789876e-04  1.867259e-04  1.947635e-04
## ASV2160      4.612110e-05  4.847891e-05  5.096340e-05  5.358183e-05
## ASV5013      5.599727e-05  5.833181e-05  6.074712e-05  6.324434e-05
## ASV2586      1.007043e-04  1.052694e-04  1.100302e-04  1.149940e-04
## ASV1442      7.904493e-05  8.270551e-05  8.652932e-05  9.052291e-05
## ASV3101      1.122964e-04  1.170215e-04  1.219155e-04  1.269817e-04
## ASV3323     -9.403827e-05 -9.848568e-05 -1.031371e-04 -1.080011e-04
## ASV1812      2.880131e-04  3.005733e-04  3.136292e-04  3.271958e-04
## ASV6120     -3.418354e-05 -3.592291e-05 -3.775464e-05 -3.968386e-05
## ASV2565      6.284246e-05  6.557179e-05  6.840771e-05  7.135332e-05
## ASV6687      3.231742e-05  3.376505e-05  3.527326e-05  3.684419e-05
## ASV5357     -2.525414e-04 -2.641477e-04 -2.762673e-04 -2.889211e-04
## ASV9383      1.254366e-04  1.309998e-04  1.367913e-04  1.428188e-04
## ASV11753    -2.161338e-04 -2.260470e-04 -2.363971e-04 -2.472016e-04
## ASV11512    -5.993396e-05 -6.268011e-05 -6.554718e-05 -6.854006e-05
## ASV2791     -9.534625e-06 -1.008665e-05 -1.067357e-05 -1.129776e-05
## ASV0664     -4.570367e-04 -4.778829e-04 -4.996366e-04 -5.223334e-04
## ASV3436      4.732036e-05  4.978582e-05  5.238812e-05  5.513549e-05
## ASV5755      3.111866e-04  3.253110e-04  3.400438e-04  3.554083e-04
## ASV10970    -3.060811e-04 -3.201105e-04 -3.347568e-04 -3.500448e-04
## ASV11798    -1.561686e-04 -1.633203e-04 -1.707859e-04 -1.785781e-04
## ASV18193    -3.060452e-04 -3.200711e-04 -3.347138e-04 -3.499978e-04
## ASV2548      3.218342e-04  3.363435e-04  3.514700e-04  3.672366e-04
## ASV3901      3.478602e-04  3.635448e-04  3.798967e-04  3.969407e-04
## ASV5197      5.967454e-06  5.874549e-06  5.745555e-06  5.576355e-06
## ASV5859      1.544191e-04  1.613966e-04  1.686727e-04  1.762586e-04
## ASV6240     -3.060309e-04 -3.200554e-04 -3.346966e-04 -3.499789e-04
## ASV7281      3.060059e-04  3.200281e-04  3.346667e-04  3.499463e-04
## ASV7635      1.719610e-04  1.799285e-04  1.882541e-04  1.969531e-04
## ASV8822     -3.059858e-04 -3.200062e-04 -3.346427e-04 -3.499201e-04
## ASV4810     -6.492337e-05 -6.769708e-05 -7.057347e-05 -7.355480e-05
## ASV5308      3.201859e-04  3.348759e-04  3.502137e-04  3.662254e-04
## ASV2749     -3.506555e-04 -3.668497e-04 -3.837678e-04 -4.014399e-04
## ASV0298      2.699140e-05  2.862106e-05  3.035878e-05  3.221224e-05
## ASV2597     -3.287999e-04 -3.440299e-04 -3.599450e-04 -3.765739e-04
## ASV5758     -1.369156e-04 -1.432163e-04 -1.497971e-04 -1.566693e-04
## ASV9987     -3.474685e-04 -3.634782e-04 -3.802002e-04 -3.976638e-04
## ASV0971      7.008575e-05  7.295190e-05  7.591530e-05  7.897759e-05
## ASV0627     -3.392315e-04 -3.549729e-04 -3.714250e-04 -3.886180e-04
## ASV1758      3.072860e-04  3.213763e-04  3.360875e-04  3.514447e-04
## ASV4559      1.338287e-06  1.448447e-06  1.567542e-06  1.696243e-06
## ASV11400    -1.268730e-05 -1.313431e-05 -1.358811e-05 -1.404771e-05
## ASV11559    -3.090710e-04 -3.233868e-04 -3.383467e-04 -3.539780e-04
## ASV3943     -3.090455e-04 -3.233589e-04 -3.383161e-04 -3.539445e-04
## ASV10389     5.772135e-05  6.021129e-05  6.279605e-05  6.547803e-05
## ASV5168      2.730412e-04  2.852477e-04  2.979633e-04  3.112058e-04
## ASV5724      1.907715e-04  1.996233e-04  2.088743e-04  2.185415e-04
## ASV6337      5.987427e-05  6.236185e-05  6.493509e-05  6.759526e-05
## ASV11063     1.726222e-04  1.801821e-04  1.880430e-04  1.962144e-04
## ASV4279     -3.296388e-05 -3.447745e-05 -3.605780e-05 -3.770762e-05
## ASV7660     -1.281001e-04 -1.341144e-04 -1.404069e-04 -1.469900e-04
## ASV8218     -1.280894e-04 -1.341027e-04 -1.403941e-04 -1.469759e-04
## ASV3574      5.023989e-04  5.258629e-04  5.504006e-04  5.760589e-04
## ASV12050    -1.280914e-04 -1.341049e-04 -1.403965e-04 -1.469785e-04
## ASV3897      1.143365e-04  1.194219e-04  1.247172e-04  1.302297e-04
## ASV3856     -3.859403e-04 -4.036632e-04 -4.221682e-04 -4.414868e-04
## ASV3024     -1.221441e-04 -1.280434e-04 -1.342288e-04 -1.407140e-04
## ASV8715     -3.002245e-04 -3.140275e-04 -3.284419e-04 -3.434928e-04
## ASV6917     -1.268433e-04 -1.322920e-04 -1.379480e-04 -1.438169e-04
## ASV1132      3.109208e-04  3.254751e-04  3.406986e-04  3.566212e-04
## ASV3583      1.564198e-04  1.638115e-04  1.715497e-04  1.796503e-04
## ASV0328      4.959076e-04  5.187784e-04  5.426695e-04  5.676232e-04
## ASV0915     -1.663486e-04 -1.741665e-04 -1.823470e-04 -1.909064e-04
## ASV2677      1.683179e-04  1.763093e-04  1.846780e-04  1.934415e-04
## ASV0599      1.699061e-04  1.775548e-04  1.855287e-04  1.938400e-04
## ASV0283     -4.520910e-04 -4.728100e-04 -4.944409e-04 -5.170205e-04
## ASV1028      1.872927e-04  1.960867e-04  2.052873e-04  2.149126e-04
## ASV0523      3.410221e-04  3.568722e-04  3.734399e-04  3.907561e-04
## ASV8201     -2.078217e-04 -2.175050e-04 -2.276284e-04 -2.382109e-04
## ASV2795     -6.518221e-05 -6.815090e-05 -7.124862e-05 -7.448043e-05
## ASV3563     -6.507884e-05 -6.804258e-05 -7.113511e-05 -7.436148e-05
## ASV1553     -1.185712e-04 -1.237277e-04 -1.290866e-04 -1.346537e-04
## ASV7155     -3.336035e-05 -3.526366e-05 -3.728236e-05 -3.942361e-05
## ASV0365      4.361607e-04  4.560246e-04  4.767521e-04  4.983768e-04
## ASV8583     -2.998483e-04 -3.135134e-04 -3.277726e-04 -3.426490e-04
## ASV5400      1.596257e-05  1.674144e-05  1.755825e-05  1.841478e-05
## ASV5908      2.317788e-04  2.420853e-04  2.528160e-04  2.639852e-04
## ASV2075      1.313550e-04  1.374746e-04  1.438724e-04  1.505604e-04
## ASV2520     -2.620208e-04 -2.742414e-04 -2.870196e-04 -3.003797e-04
## ASV9596     -1.286866e-04 -1.343655e-04 -1.402744e-04 -1.464209e-04
## ASV1131     -4.290695e-05 -4.461936e-05 -4.638522e-05 -4.820489e-05
## ASV0579     -8.519127e-05 -8.906803e-05 -9.311320e-05 -9.733340e-05
## ASV0288     -4.167540e-04 -4.356602e-04 -4.553812e-04 -4.759481e-04
## ASV4053      6.855895e-05  7.133343e-05  7.419716e-05  7.715089e-05
## ASV1736     -2.226258e-04 -2.328347e-04 -2.434931e-04 -2.546191e-04
## ASV1254      2.290761e-04  2.392940e-04  2.499365e-04  2.610184e-04
## ASV9038     -3.644162e-04 -3.812645e-04 -3.988669e-04 -4.172550e-04
## ASV4746      3.325850e-04  3.481497e-04  3.644299e-04  3.814574e-04
## ASV5803      1.260783e-04  1.319028e-04  1.379880e-04  1.443448e-04
## ASV0525      1.449175e-05  1.519347e-05  1.592956e-05  1.670173e-05
## ASV1974      1.919345e-04  2.004271e-04  2.092653e-04  2.184603e-04
## ASV1827      3.217389e-04  3.361914e-04  3.512532e-04  3.669464e-04
## ASV30780     1.573000e-05  1.633046e-05  1.694592e-05  1.757587e-05
## ASV9342      1.197407e-05  1.266492e-05  1.339963e-05  1.418125e-05
## ASV21626    -3.043411e-04 -3.182369e-04 -3.327389e-04 -3.478708e-04
## ASV1232     -2.152511e-04 -2.249962e-04 -2.351593e-04 -2.457560e-04
## ASV5578     -2.174915e-04 -2.275323e-04 -2.380216e-04 -2.489781e-04
## ASV5868      2.281972e-04  2.383312e-04  2.488826e-04  2.598657e-04
## ASV13625    -9.454965e-05 -9.881505e-05 -1.032616e-04 -1.078960e-04
## ASV3614      3.501787e-05  3.646253e-05  3.795632e-05  3.949994e-05
## ASV2128      1.965507e-04  2.057028e-04  2.152707e-04  2.252724e-04
## ASV5086      4.293105e-05  4.484446e-05  4.683680e-05  4.891073e-05
## ASV6614     -2.174816e-04 -2.275214e-04 -2.380097e-04 -2.489650e-04
## ASV9451     -2.174637e-04 -2.275019e-04 -2.379883e-04 -2.489416e-04
## ASV9533     -2.174459e-04 -2.274823e-04 -2.379669e-04 -2.489182e-04
## ASV10697     2.777381e-06  3.036951e-06  3.320245e-06  3.629357e-06
## ASV1473     -1.018469e-04 -1.063062e-04 -1.109426e-04 -1.157616e-04
## ASV1414     -6.453091e-05 -6.756617e-05 -7.074113e-05 -7.406185e-05
## ASV1567     -6.334805e-05 -6.650379e-05 -6.982227e-05 -7.331231e-05
## ASV6395     -2.193053e-04 -2.295196e-04 -2.401989e-04 -2.513633e-04
## ASV2366      8.798756e-05  9.167781e-05  9.549870e-05  9.945257e-05
## ASV2537      8.780565e-05  9.155720e-05  9.544911e-05  9.948486e-05
## ASV5378     -2.192965e-04 -2.295099e-04 -2.401882e-04 -2.513515e-04
## ASV5929     -2.307958e-04 -2.415356e-04 -2.527633e-04 -2.645000e-04
## ASV6360      1.830254e-04  1.912094e-04  1.997341e-04  2.086113e-04
## ASV7916     -3.724763e-05 -3.913213e-05 -4.111667e-05 -4.320693e-05
## ASV13322     7.285497e-05  7.636082e-05  8.003651e-05  8.389030e-05
## ASV6207     -2.773961e-04 -2.901423e-04 -3.034521e-04 -3.173485e-04
## ASV8823     -2.208054e-04 -2.310086e-04 -2.416683e-04 -2.528037e-04
## ASV1379      3.072908e-04  3.214351e-04  3.362072e-04  3.516327e-04
## ASV3259     -3.072656e-04 -3.214076e-04 -3.361771e-04 -3.515998e-04
## ASV18748     9.128712e-07  1.086713e-06  1.280800e-06  1.497158e-06
## ASV3570      6.681406e-05  6.992285e-05  7.317270e-05  7.656964e-05
## ASV0790     -6.621389e-05 -6.866087e-05 -7.116328e-05 -7.371885e-05
## ASV5149     -2.807646e-04 -2.935779e-04 -3.069496e-04 -3.209016e-04
## ASV1730     -2.897976e-04 -3.030760e-04 -3.169380e-04 -3.314072e-04
## ASV3488     -2.373928e-05 -2.475331e-05 -2.580536e-05 -2.689640e-05
## ASV5486     -3.142552e-04 -3.290645e-04 -3.445642e-04 -3.607859e-04
## ASV1319      4.939116e-05  5.105313e-05  5.273460e-05  5.443174e-05
## ASV15328    -2.160792e-04 -2.259894e-04 -2.363363e-04 -2.471377e-04
## ASV5994      3.120189e-04  3.263692e-04  3.413553e-04  3.570032e-04
## ASV4992     -2.502138e-05 -2.609875e-05 -2.721707e-05 -2.837738e-05
## ASV1788     -3.409000e-04 -3.560519e-04 -3.718283e-04 -3.882506e-04
## ASV3264     -3.903322e-06 -3.897141e-06 -3.873412e-06 -3.829819e-06
## ASV4895      1.465304e-05  1.524230e-05  1.584980e-05  1.647558e-05
## ASV9218     -5.422797e-06 -5.475606e-06 -5.512530e-06 -5.531245e-06
## ASV0736     -6.625248e-06 -7.112301e-06 -7.637806e-06 -8.204881e-06
## ASV0916      2.160365e-04  2.259428e-04  2.362856e-04  2.470824e-04
## ASV15761    -2.160189e-04 -2.259235e-04 -2.362645e-04 -2.470593e-04
## ASV4191      2.691943e-04  2.813070e-04  2.939320e-04  3.070881e-04
## ASV3268     -5.519900e-05 -5.757530e-05 -6.004173e-05 -6.260054e-05
## ASV15321    -3.521935e-05 -3.700494e-05 -3.888522e-05 -4.086552e-05
## ASV0708     -2.158488e-04 -2.259301e-04 -2.364728e-04 -2.474971e-04
## ASV4100      2.544791e-05  2.646818e-05  2.751989e-05  2.860305e-05
## ASV1627      1.734535e-04  1.808903e-04  1.886100e-04  1.966202e-04
## ASV7045     -1.911357e-04 -1.999534e-04 -2.091639e-04 -2.187832e-04
## ASV3271      4.579711e-05  4.742381e-05  4.908234e-05  5.077085e-05
## ASV6200     -3.327681e-05 -3.487668e-05 -3.655438e-05 -3.831381e-05
## ASV2727     -2.256776e-04 -2.364034e-04 -2.476358e-04 -2.593981e-04
## ASV3523     -2.987854e-04 -3.124293e-04 -3.266685e-04 -3.415265e-04
## ASV2259      2.016515e-04  2.109154e-04  2.205891e-04  2.306894e-04
## ASV0181      2.963201e-04  3.097721e-04  3.238043e-04  3.384389e-04
## ASV1680      5.936118e-04  6.207908e-04  6.491630e-04  6.787760e-04
## ASV0176      6.038365e-05  6.300624e-05  6.573048e-05  6.855917e-05
## ASV10458    -2.168912e-04 -2.268767e-04 -2.373059e-04 -2.481969e-04
## ASV10658    -2.168734e-04 -2.268573e-04 -2.372846e-04 -2.481736e-04
## ASV16807    -2.168557e-04 -2.268378e-04 -2.372633e-04 -2.481503e-04
## ASV2113     -2.168379e-04 -2.268184e-04 -2.372421e-04 -2.481271e-04
## ASV2403      2.223782e-04  2.324734e-04  2.430036e-04  2.539855e-04
## ASV2484     -2.168305e-04 -2.268103e-04 -2.372332e-04 -2.481173e-04
## ASV8876     -2.168128e-04 -2.267909e-04 -2.372119e-04 -2.480941e-04
## ASV0386      3.171797e-04  3.319777e-04  3.474515e-04  3.636304e-04
## ASV0351      8.748836e-05  9.137627e-05  9.542369e-05  9.963595e-05
## ASV4942     -1.235476e-04 -1.292004e-04 -1.351015e-04 -1.412609e-04
## ASV5128     -9.574047e-05 -1.002063e-04 -1.048755e-04 -1.097570e-04
## ASV3496      1.074671e-04  1.126936e-04  1.181785e-04  1.239348e-04
## ASV3329      3.157341e-04  3.304250e-04  3.457828e-04  3.618361e-04
## ASV7878     -2.160744e-04 -2.259810e-04 -2.363235e-04 -2.471196e-04
## ASV8251     -8.208324e-05 -8.584403e-05 -8.976991e-05 -9.386743e-05
## ASV15958    -7.094251e-05 -7.424353e-05 -7.769423e-05 -8.130101e-05
## ASV7972     -3.089266e-04 -3.232252e-04 -3.381657e-04 -3.537753e-04
## ASV2088      3.089012e-04  3.231973e-04  3.381352e-04  3.537419e-04
## ASV3054     -1.453998e-04 -1.521319e-04 -1.591662e-04 -1.665154e-04
## ASV4494     -3.088656e-04 -3.231583e-04 -3.380926e-04 -3.536952e-04
## ASV0087     -5.853982e-04 -6.121899e-04 -6.401566e-04 -6.693454e-04
## ASV1614     -2.393311e-04 -2.502669e-04 -2.616805e-04 -2.735908e-04
## ASV3037     -1.325881e-04 -1.386830e-04 -1.450479e-04 -1.516935e-04
## ASV6615     -3.477589e-05 -3.654059e-05 -3.839868e-05 -4.035535e-05
## ASV1027      8.982694e-05  9.387807e-05  9.810108e-05  1.025023e-04
## ASV2754     -5.609802e-05 -5.886336e-05 -6.176835e-05 -6.482023e-05
## ASV0536     -4.380565e-05 -4.592073e-05 -4.813880e-05 -5.046491e-05
## ASV2318     -9.278519e-05 -9.716034e-05 -1.017397e-04 -1.065326e-04
## ASV5954      1.841865e-04  1.923187e-04  2.007808e-04  2.095839e-04
## ASV9028      1.297182e-04  1.357088e-04  1.419670e-04  1.485039e-04
## ASV6600     -2.193987e-04 -2.296201e-04 -2.403069e-04 -2.514792e-04
## ASV1923     -5.775855e-05 -6.034548e-05 -6.304030e-05 -6.584676e-05
## ASV4034     -4.245669e-05 -4.466780e-05 -4.700084e-05 -4.946296e-05
## ASV9933     -2.193734e-04 -2.295924e-04 -2.402764e-04 -2.514458e-04
## ASV1575      4.109726e-05  4.285539e-05  4.468015e-05  4.657335e-05
## ASV7812     -3.728618e-04 -3.899662e-04 -4.078241e-04 -4.264661e-04
## ASV0515      2.400316e-04  2.507856e-04  2.619899e-04  2.736605e-04
## ASV1149     -2.726083e-05 -2.886231e-05 -3.056608e-05 -3.237908e-05
## ASV3791      1.003106e-04  1.050563e-04  1.100249e-04  1.152265e-04
## ASV4065     -3.487396e-04 -3.647681e-04 -3.815055e-04 -3.989804e-04
## ASV10631    -1.976150e-05 -2.083456e-05 -2.197076e-05 -2.317418e-05
## ASV2359     -3.446772e-04 -3.599085e-04 -3.757598e-04 -3.922518e-04
## ASV3206     -2.170558e-04 -2.270590e-04 -2.375079e-04 -2.484207e-04
## ASV4415      1.766828e-04  1.848245e-04  1.933281e-04  2.022085e-04
## ASV4467     -1.555702e-04 -1.626596e-04 -1.700572e-04 -1.777751e-04
## ASV5598      2.661789e-04  2.787537e-04  2.919175e-04  3.056975e-04
## ASV5910     -2.394672e-04 -2.505227e-04 -2.620724e-04 -2.741371e-04
## ASV9494     -2.170073e-04 -2.270060e-04 -2.374498e-04 -2.483571e-04
## ASV6548     -1.772171e-04 -1.853514e-04 -1.938451e-04 -2.027127e-04
## ASV8669     -2.169752e-04 -2.269709e-04 -2.374114e-04 -2.483151e-04
## ASV0674      1.348631e-04  1.408250e-04  1.470287e-04  1.534820e-04
## ASV0061     -6.512211e-05 -6.875295e-05 -7.260130e-05 -7.668092e-05
## ASV0310     -1.342222e-04 -1.402090e-04 -1.464471e-04 -1.529457e-04
## ASV0582      4.136624e-05  4.305699e-05  4.480386e-05  4.660753e-05
## ASV0739      4.111674e-04  4.303180e-04  4.503391e-04  4.712682e-04
## ASV1557      1.717273e-04  1.798789e-04  1.884155e-04  1.973551e-04
## ASV0146      3.838193e-04  4.008658e-04  4.186131e-04  4.370851e-04
## ASV3832      3.919962e-04  4.096847e-04  4.281257e-04  4.473468e-04
## ASV0734      8.771187e-05  9.182628e-05  9.612983e-05  1.006308e-04
## ASV3036     -2.873700e-04 -3.007713e-04 -3.147841e-04 -3.294353e-04
## ASV0240      7.722173e-05  8.070154e-05  8.432896e-05  8.810940e-05
## ASV2513     -4.312087e-04 -4.508043e-04 -4.712468e-04 -4.925689e-04
## ASV1118     -1.148773e-04 -1.203397e-04 -1.260599e-04 -1.320498e-04
## ASV7286     -2.164182e-04 -2.263591e-04 -2.367394e-04 -2.475771e-04
## ASV1077      2.890636e-04  3.021189e-04  3.157312e-04  3.299215e-04
## ASV1255     -2.163802e-04 -2.263175e-04 -2.366939e-04 -2.475274e-04
## ASV1794     -1.312261e-05 -1.375821e-05 -1.442484e-05 -1.512400e-05
## ASV2439     -2.163632e-04 -2.262990e-04 -2.366737e-04 -2.475053e-04
## ASV2467     -2.163455e-04 -2.262796e-04 -2.366525e-04 -2.474821e-04
## ASV3346     -2.163279e-04 -2.262603e-04 -2.366314e-04 -2.474590e-04
## ASV3973     -2.163102e-04 -2.262409e-04 -2.366102e-04 -2.474359e-04
## ASV4521      9.555845e-05  9.985678e-05  1.043362e-04  1.090031e-04
## ASV1909     -2.572070e-04 -2.692891e-04 -2.819304e-04 -2.951560e-04
## ASV3855     -1.938723e-04 -2.026998e-04 -2.119102e-04 -2.215184e-04
## ASV0810      2.587382e-04  2.706958e-04  2.831886e-04  2.962388e-04
## ASV1765      3.085636e-04  3.229413e-04  3.379738e-04  3.536894e-04
## ASV0763      1.677375e-04  1.754263e-04  1.834534e-04  1.918326e-04
## ASV0302     -1.828900e-04 -1.911619e-04 -1.997875e-04 -2.087798e-04
## ASV2643     -2.490409e-04 -2.600552e-04 -2.715200e-04 -2.834507e-04
## ASV0440      9.665448e-05  1.012008e-04  1.059569e-04  1.109320e-04
## ASV4899     -1.752809e-04 -1.830528e-04 -1.911423e-04 -1.995599e-04
## ASV0287     -1.065346e-04 -1.114938e-04 -1.166788e-04 -1.220995e-04
## ASV3220      1.333151e-04  1.395529e-04  1.460764e-04  1.528980e-04
## ASV1007     -7.663603e-05 -8.000368e-05 -8.350600e-05 -8.714712e-05
## ASV2929     -4.888220e-05 -5.094287e-05 -5.307777e-05 -5.528839e-05
## ASV1496     -1.836953e-04 -1.923164e-04 -2.013358e-04 -2.107714e-04
## ASV4975      8.027407e-05  8.399596e-05  8.788503e-05  9.194822e-05
## ASV4392     -1.108204e-05 -1.139273e-05 -1.169820e-05 -1.199640e-05
## ASV4653     -2.187620e-04 -2.289237e-04 -2.395452e-04 -2.506463e-04
## ASV0230     -1.120112e-04 -1.172751e-04 -1.227826e-04 -1.285447e-04
## ASV0840      1.578238e-04  1.651406e-04  1.727873e-04  1.807780e-04
## ASV4132     -4.716355e-05 -4.943207e-05 -5.181042e-05 -5.430394e-05
## ASV3344      1.644107e-04  1.718034e-04  1.795084e-04  1.875370e-04
## ASV12096    -2.218696e-04 -2.322092e-04 -2.430187e-04 -2.543185e-04
## ASV1550      7.394453e-05  7.704941e-05  8.026519e-05  8.359404e-05
## ASV3542     -3.290008e-04 -3.444479e-04 -3.606071e-04 -3.775099e-04
## ASV8795     -1.273413e-04 -1.332812e-04 -1.394919e-04 -1.459852e-04
## ASV2532     -6.878543e-06 -7.259396e-06 -7.663104e-06 -8.091149e-06
## ASV3087      5.268986e-05  5.501354e-05  5.743112e-05  5.994560e-05
## ASV9476     -1.273339e-04 -1.332730e-04 -1.394830e-04 -1.459754e-04
## ASV13721    -1.273233e-04 -1.332615e-04 -1.394703e-04 -1.459615e-04
## ASV3842      2.096309e-04  2.190310e-04  2.288255e-04  2.390285e-04
## ASV1663      3.773275e-04  3.942607e-04  4.119060e-04  4.302892e-04
## ASV0432      8.869790e-05  9.267186e-05  9.681227e-05  1.011251e-04
## ASV4356      3.734149e-04  3.905348e-04  4.084085e-04  4.270664e-04
## ASV4524      9.086743e-05  9.520565e-05  9.975093e-05  1.045131e-04
## ASV0169     -1.843994e-04 -1.930656e-04 -2.021331e-04 -2.116195e-04
## ASV0368     -1.584968e-04 -1.659386e-04 -1.737242e-04 -1.818687e-04
## ASV2603      7.424987e-08  7.668190e-08  7.869425e-08  8.015904e-08
## ASV3777      2.090340e-04  2.186798e-04  2.287559e-04  2.392801e-04
## ASV3978      1.814672e-04  1.897291e-04  1.983489e-04  2.073404e-04
## ASV0413     -1.495591e-04 -1.565764e-04 -1.639173e-04 -1.715962e-04
## ASV0997     -4.540442e-08 -4.511248e-08 -4.414819e-08 -4.236102e-08
## ASV1195     -4.540393e-08 -4.511305e-08 -4.415016e-08 -4.236484e-08
## ASV2522     -9.838588e-05 -1.029011e-04 -1.076157e-04 -1.125375e-04
## ASV4733      1.797086e-04  1.880229e-04  1.967099e-04  2.057851e-04
## ASV1063      3.151654e-04  3.300566e-04  3.456453e-04  3.619636e-04
## ASV0612     -4.018157e-04 -4.205941e-04 -4.402335e-04 -4.607719e-04
## ASV1903     -3.151078e-04 -3.299934e-04 -3.455761e-04 -3.618877e-04
## ASV3576     -9.184047e-05 -9.637599e-05 -1.011419e-04 -1.061502e-04
## ASV4285     -2.245470e-04 -2.350562e-04 -2.460478e-04 -2.575429e-04
## ASV3406     -1.167680e-04 -1.221807e-04 -1.278374e-04 -1.337485e-04
## ASV2379     -2.168643e-04 -2.263515e-04 -2.362162e-04 -2.464703e-04
## ASV0528      2.742453e-04  2.869582e-04  3.002434e-04  3.141251e-04
## ASV6190     -3.565360e-05 -3.738923e-05 -3.921060e-05 -4.112199e-05
## ASV1537     -2.826926e-06 -2.854085e-06 -2.872475e-06 -2.880761e-06
## ASV16780    -2.439048e-04 -2.550773e-04 -2.667410e-04 -2.789156e-04
## ASV0477      6.057235e-04  6.336477e-04  6.628158e-04  6.932790e-04
## ASV1499      1.388124e-04  1.456236e-04  1.527755e-04  1.602853e-04
## ASV14736     1.050981e-04  1.098892e-04  1.148890e-04  1.201059e-04
## ASV0179     -8.738256e-05 -9.145842e-05 -9.572015e-05 -1.001758e-04
## ASV3153      7.443626e-06  8.051342e-06  8.710997e-06  9.427066e-06
## ASV0266      2.830959e-04  2.962541e-04  3.100090e-04  3.243863e-04
## ASV0761      4.190754e-04  4.381816e-04  4.581197e-04  4.789226e-04
## ASV0269     -4.121738e-05 -4.335629e-05 -4.561314e-05 -4.799497e-05
## ASV7259     -7.948813e-05 -8.343780e-05 -8.758867e-05 -9.195122e-05
## ASV2067     -8.876022e-05 -9.271402e-05 -9.683140e-05 -1.011180e-04
## ASV2985     -2.486124e-04 -2.600812e-04 -2.720602e-04 -2.845702e-04
## ASV0975     -3.769367e-04 -3.944525e-04 -4.127614e-04 -4.318973e-04
## ASV2240      2.241273e-04  2.341833e-04  2.446626e-04  2.555807e-04
## ASV2297      7.282725e-05  7.589568e-05  7.907503e-05  8.236769e-05
## ASV2657      9.427290e-05  9.844347e-05  1.027844e-04  1.073014e-04
## ASV3784      3.396406e-06  3.711185e-06  4.054329e-06  4.428280e-06
## ASV4333      3.395869e-06  3.710571e-06  4.053628e-06  4.427480e-06
## ASV5547      1.934092e-04  2.018605e-04  2.106474e-04  2.197805e-04
## ASV5813      7.849665e-05  8.194960e-05  8.554137e-05  8.927637e-05
## ASV8049      9.412908e-05  9.838913e-05  1.028320e-04  1.074646e-04
## ASV8661     -3.405481e-06 -3.721040e-06 -4.065027e-06 -4.439887e-06
## ASV9510      1.099853e-04  1.149394e-04  1.201035e-04  1.254853e-04
## ASV1401      5.772964e-05  6.030717e-05  6.299211e-05  6.578827e-05
## ASV1417     -1.151711e-04 -1.200047e-04 -1.250113e-04 -1.301944e-04
## ASV2169      4.014016e-04  4.198185e-04  4.390481e-04  4.591235e-04
## ASV5354     -3.417451e-06 -3.734128e-06 -4.079334e-06 -4.455525e-06
## ASV5379     -3.416911e-06 -3.733511e-06 -4.078630e-06 -4.454721e-06
## ASV6078     -3.416371e-06 -3.732894e-06 -4.077925e-06 -4.453916e-06
## ASV6417      2.453316e-04  2.564275e-04  2.679981e-04  2.800613e-04
## ASV8304      1.777684e-04  1.856680e-04  1.938931e-04  2.024546e-04
## ASV8766     -3.436996e-06 -3.755391e-06 -4.102457e-06 -4.480660e-06
## ASV10861     7.422667e-05  7.748155e-05  8.086610e-05  8.438432e-05
## ASV2057      3.969419e-04  4.151773e-04  4.342192e-04  4.541002e-04
## ASV4499      1.391186e-04  1.451565e-04  1.514294e-04  1.579439e-04
## ASV7415      4.402138e-05  4.606996e-05  4.821088e-05  5.044795e-05
## ASV2475     -1.702020e-04 -1.780682e-04 -1.862869e-04 -1.948729e-04
## ASV3517     -2.785502e-04 -2.916295e-04 -3.053139e-04 -3.196308e-04
## ASV1864      1.867291e-04  1.951400e-04  2.039073e-04  2.130440e-04
## ASV2756      2.157039e-04  2.255784e-04  2.358863e-04  2.466451e-04
## ASV0778      2.156863e-04  2.255591e-04  2.358653e-04  2.466222e-04
## ASV3201      4.930993e-05  5.184574e-05  5.451901e-05  5.733771e-05
## ASV3358      2.156714e-04  2.255429e-04  2.358476e-04  2.466028e-04
## ASV5681     -2.156538e-04 -2.255237e-04 -2.358266e-04 -2.465798e-04
## ASV7256      1.045103e-04  1.093647e-04  1.144400e-04  1.197461e-04
## ASV1704     -2.204610e-04 -2.304817e-04 -2.409350e-04 -2.518375e-04
## ASV4445      3.466542e-04  3.619365e-04  3.778374e-04  3.943773e-04
## ASV8649     -2.156178e-04 -2.254844e-04 -2.357837e-04 -2.465330e-04
## ASV0597      2.241034e-04  2.343519e-04  2.450493e-04  2.562135e-04
## ASV0861      2.852874e-04  2.982197e-04  3.117080e-04  3.257734e-04
## ASV2423      3.461197e-04  3.618715e-04  3.783055e-04  3.954481e-04
## ASV1548      1.686288e-04  1.759634e-04  1.835849e-04  1.915014e-04
## ASV2564      2.880030e-04  3.009695e-04  3.144843e-04  3.285673e-04
## ASV2999      4.790563e-04  5.005537e-04  5.229551e-04  5.462928e-04
## ASV4543     -1.729691e-04 -1.810863e-04 -1.895788e-04 -1.984635e-04
## ASV8452      1.644071e-04  1.716867e-04  1.792631e-04  1.871460e-04
## ASV17287    -3.466006e-05 -3.644297e-05 -3.832279e-05 -4.030518e-05
## ASV3503     -2.213515e-04 -2.317598e-04 -2.426511e-04 -2.540474e-04
## ASV4727     -3.812395e-05 -4.012779e-05 -4.224389e-05 -4.447902e-05
## ASV5995     -1.883175e-04 -1.971584e-04 -2.064084e-04 -2.160857e-04
## ASV1665     -6.030534e-05 -6.313267e-05 -6.609033e-05 -6.918412e-05
## ASV2690     -2.817268e-04 -2.947166e-04 -3.082854e-04 -3.224571e-04
## ASV2823     -2.288704e-05 -2.389088e-05 -2.493492e-05 -2.602047e-05
## ASV5241     -3.767085e-04 -3.940736e-04 -4.122116e-04 -4.311541e-04
## ASV5473     -1.082944e-04 -1.134334e-04 -1.188152e-04 -1.244511e-04
## ASV2785      4.890403e-05  5.126628e-05  5.374364e-05  5.634175e-05
## ASV6645     -1.591512e-04 -1.664233e-04 -1.740132e-04 -1.819334e-04
## ASV0562      6.426067e-05  6.700917e-05  6.985964e-05  7.281435e-05
## ASV1163      6.507429e-05  6.812335e-05  7.131245e-05  7.464771e-05
## ASV1825      1.227133e-04  1.282417e-04  1.340040e-04  1.400086e-04
## ASV3795      2.710459e-04  2.834065e-04  2.963059e-04  3.097652e-04
## ASV3869     -6.087778e-05 -6.384186e-05 -6.695290e-05 -7.021840e-05
## ASV4330      2.089820e-04  2.185701e-04  2.285809e-04  2.390315e-04
## ASV6754      7.944125e-05  8.308354e-05  8.688600e-05  9.085502e-05
## ASV4598     -2.151652e-06 -2.356496e-06 -2.580559e-06 -2.825600e-06
## ASV2100      1.604196e-04  1.675785e-04  1.750349e-04  1.827994e-04
## ASV3518      7.973426e-05  8.328289e-05  8.697746e-05  9.082282e-05
## ASV3823      3.304184e-04  3.454056e-04  3.610381e-04  3.773403e-04
## ASV7357      2.028351e-04  2.121012e-04  2.217723e-04  2.318643e-04
## ASV7403     -2.592090e-04 -2.709987e-04 -2.832987e-04 -2.961287e-04
## ASV2934     -1.106058e-05 -1.148548e-05 -1.192132e-05 -1.236779e-05
## ASV5277     -1.349364e-04 -1.410702e-04 -1.474689e-04 -1.541427e-04
## ASV0281     -3.975871e-04 -4.157371e-04 -4.346796e-04 -4.544460e-04
## ASV11181    -1.479608e-04 -1.550268e-04 -1.624312e-04 -1.701904e-04
## ASV0254     -5.144325e-05 -5.339195e-05 -5.538803e-05 -5.742980e-05
## ASV0201     -6.880843e-05 -7.217283e-05 -7.570541e-05 -7.941489e-05
## ASV3656     -1.706728e-04 -1.788996e-04 -1.875267e-04 -1.965738e-04
## ASV7994     -3.072664e-04 -3.214262e-04 -3.362165e-04 -3.516631e-04
## ASV3584     -9.956505e-05 -1.037166e-04 -1.080151e-04 -1.124633e-04
## ASV2157      3.157679e-04  3.299807e-04  3.447960e-04  3.602361e-04
## ASV2935     -4.065484e-05 -4.253509e-05 -4.449965e-05 -4.655204e-05
## ASV9024     -2.876784e-04 -3.007112e-04 -3.143035e-04 -3.284764e-04
## ASV7711      1.723401e-04  1.804721e-04  1.889841e-04  1.978933e-04
## ASV11330    -2.181673e-04 -2.282742e-04 -2.388360e-04 -2.498721e-04
## ASV1875      1.922110e-04  2.010534e-04  2.102888e-04  2.199332e-04
## ASV5861      1.441065e-04  1.509113e-04  1.580341e-04  1.654895e-04
## ASV11562     1.262558e-05  1.323411e-05  1.387198e-05  1.454057e-05
## ASV18559    -2.181615e-04 -2.282678e-04 -2.388290e-04 -2.498645e-04
## ASV4384      2.112543e-04  2.212067e-04  2.316225e-04  2.425226e-04
## ASV1302      4.304862e-04  4.496150e-04  4.695333e-04  4.902685e-04
## ASV4673     -2.865981e-04 -2.999676e-04 -3.139466e-04 -3.285616e-04
## ASV1956      4.791898e-05  4.990657e-05  5.196474e-05  5.409510e-05
## ASV3286      1.999035e-04  2.093292e-04  2.191941e-04  2.295183e-04
## ASV4866     -3.135365e-04 -3.282773e-04 -3.437022e-04 -3.598420e-04
## ASV3129     -1.538366e-04 -1.610187e-04 -1.685296e-04 -1.763837e-04
## ASV4104      3.535456e-04  3.697834e-04  3.867386e-04  4.044405e-04
## ASV8983      2.885218e-06  3.016821e-06  3.154520e-06  3.298640e-06
## ASV2201      1.351473e-04  1.411100e-04  1.473139e-04  1.537669e-04
## ASV3055      9.244486e-05  9.637315e-05  1.004468e-04  1.046693e-04
## ASV0534     -4.607325e-04 -4.817069e-04 -5.035904e-04 -5.264184e-04
## ASV1019      1.550666e-05  1.639052e-05  1.732952e-05  1.832739e-05
## ASV18482    -2.143304e-04 -2.240754e-04 -2.342419e-04 -2.448460e-04
## ASV2694      7.143481e-05  7.447648e-05  7.763117e-05  8.090162e-05
## ASV3412     -6.584816e-05 -6.870079e-05 -7.166335e-05 -7.473878e-05
## ASV4174     -2.143088e-04 -2.240518e-04 -2.342161e-04 -2.448179e-04
## ASV4281     -2.142914e-04 -2.240328e-04 -2.341953e-04 -2.447953e-04
## ASV4949      2.404089e-04  2.511717e-04  2.623849e-04  2.740648e-04
## ASV5881      1.129847e-04  1.180969e-04  1.234277e-04  1.289854e-04
## ASV6299     -9.500936e-05 -9.922966e-05 -1.036232e-04 -1.081957e-04
## ASV0676      2.459997e-04  2.571043e-04  2.686825e-04  2.807521e-04
## ASV1066     -1.677910e-04 -1.753188e-04 -1.831624e-04 -1.913332e-04
## ASV1300     -1.435270e-04 -1.500168e-04 -1.567838e-04 -1.638382e-04
## ASV6455      7.005032e-05  7.327632e-05  7.664580e-05  8.016467e-05
## ASV3455     -2.142863e-04 -2.240272e-04 -2.341892e-04 -2.447886e-04
## ASV6531     -2.142690e-04 -2.240083e-04 -2.341685e-04 -2.447660e-04
## ASV0490      4.283822e-04  4.475938e-04  4.676154e-04  4.884768e-04
## ASV2588      2.343976e-05  2.486813e-05  2.639180e-05  2.801754e-05
## ASV5364      1.349411e-04  1.410454e-04  1.474107e-04  1.540466e-04
## ASV0981     -2.993739e-04 -3.133244e-04 -3.279102e-04 -3.431588e-04
## ASV1563     -6.147401e-05 -6.434499e-05 -6.734762e-05 -7.048776e-05
## ASV0376     -2.872353e-04 -3.006156e-04 -3.146045e-04 -3.292281e-04
## ASV7308     -1.579799e-06 -1.733090e-06 -1.901190e-06 -2.085517e-06
## ASV4817      4.598019e-05  4.790762e-05  4.990311e-05  5.196785e-05
## ASV8716     -3.038543e-04 -3.170108e-04 -3.306796e-04 -3.448757e-04
## ASV1849      3.874649e-04  4.045055e-04  4.222310e-04  4.406631e-04
## ASV9423     -2.996219e-04 -3.132046e-04 -3.273717e-04 -3.421455e-04
## ASV7690      1.130848e-05  1.186557e-05  1.245036e-05  1.306422e-05
## ASV4901      1.655454e-04  1.732227e-04  1.812460e-04  1.896299e-04
## ASV1830     -5.298129e-05 -5.580674e-05 -5.879340e-05 -6.195116e-05
## ASV2316     -2.226306e-04 -2.322981e-04 -2.423461e-04 -2.527863e-04
## ASV0693      3.317602e-04  3.470831e-04  3.630909e-04  3.798120e-04
## ASV1243     -1.822045e-05 -1.883297e-05 -1.945206e-05 -2.007615e-05
## ASV3867      8.738413e-05  9.148927e-05  9.578421e-05  1.002774e-04
## ASV7932      1.880890e-04  1.967610e-04  2.058190e-04  2.152787e-04
## ASV12608     1.361176e-04  1.426324e-04  1.494599e-04  1.566151e-04
## ASV1661      1.969194e-04  2.059168e-04  2.153071e-04  2.251061e-04
## ASV3957      2.071346e-04  2.167475e-04  2.267951e-04  2.372959e-04
## ASV0830     -3.265190e-04 -3.414085e-04 -3.569467e-04 -3.731590e-04
## ASV2078      3.709123e-04  3.879597e-04  4.057626e-04  4.243520e-04
## ASV13932    -2.188716e-04 -2.290446e-04 -2.396786e-04 -2.507935e-04
## ASV5300     -2.188535e-04 -2.290248e-04 -2.396569e-04 -2.507698e-04
## ASV1014     -1.175944e-04 -1.229512e-04 -1.285403e-04 -1.343707e-04
## ASV13059    -6.785500e-05 -7.127168e-05 -7.486667e-05 -7.864966e-05
## ASV4340      4.446510e-05  4.643846e-05  4.849325e-05  5.063232e-05
## ASV5591     -3.641365e-04 -3.807253e-04 -3.980346e-04 -4.160926e-04
## ASV6040     -2.911441e-04 -3.044637e-04 -3.183670e-04 -3.328769e-04
## ASV3904     -1.206413e-04 -1.263171e-04 -1.322562e-04 -1.384704e-04
## ASV2267     -3.404808e-05 -3.562267e-05 -3.726749e-05 -3.898539e-05
## ASV0573     -2.722604e-04 -2.843718e-04 -2.969827e-04 -3.101104e-04
## ASV0851     -2.937525e-04 -3.071909e-04 -3.212177e-04 -3.358561e-04
## ASV7805      9.204629e-05  9.642095e-05  1.010029e-04  1.058017e-04
## ASV3379      3.927708e-04  4.104212e-04  4.288173e-04  4.479866e-04
## ASV0825      1.780715e-04  1.865158e-04  1.953576e-04  2.046152e-04
## ASV2461      2.056079e-04  2.149311e-04  2.246558e-04  2.347972e-04
## ASV2783      2.870449e-04  3.001691e-04  3.138679e-04  3.281640e-04
## ASV0925      3.214162e-04  3.358867e-04  3.509696e-04  3.666874e-04
## ASV7023     -3.065115e-04 -3.207268e-04 -3.355830e-04 -3.511075e-04
## ASV5319      5.573913e-05  5.836327e-05  6.110867e-05  6.398064e-05
## ASV3213      1.913284e-04  2.002179e-04  2.095092e-04  2.192195e-04
## ASV3748     -4.764450e-05 -5.001007e-05 -5.249714e-05 -5.511227e-05
## ASV5491     -6.983584e-05 -7.322653e-05 -7.678463e-05 -8.051862e-05
## ASV7931      1.205063e-04  1.260832e-04  1.319102e-04  1.379976e-04
## ASV12767    -2.198780e-04 -2.301462e-04 -2.408844e-04 -2.521132e-04
## ASV6389      2.215563e-04  2.318710e-04  2.426548e-04  2.539278e-04
## ASV14867    -2.198594e-04 -2.301259e-04 -2.408622e-04 -2.520888e-04
## ASV5105      1.280826e-04  1.341468e-04  1.404957e-04  1.471423e-04
## ASV15927    -2.191257e-04 -2.293211e-04 -2.399794e-04 -2.511205e-04
## ASV2004      7.522092e-05  7.864849e-05  8.222544e-05  8.595771e-05
## ASV5554     -4.361420e-06 -4.982856e-06 -5.670126e-06 -6.429324e-06
## ASV10929    -1.533474e-04 -1.604875e-04 -1.679527e-04 -1.757570e-04
## ASV12778    -7.564865e-05 -7.914771e-05 -8.280386e-05 -8.662373e-05
## ASV14006    -2.190851e-04 -2.292766e-04 -2.399306e-04 -2.510671e-04
## ASV1603      2.142113e-04  2.242145e-04  2.346755e-04  2.456144e-04
## ASV11948     1.102426e-04  1.151331e-04  1.202237e-04  1.255209e-04
## ASV12912    -2.200824e-04 -2.303687e-04 -2.411265e-04 -2.523764e-04
## ASV13147    -2.200642e-04 -2.303487e-04 -2.411045e-04 -2.523523e-04
## ASV14761    -2.200459e-04 -2.303287e-04 -2.410826e-04 -2.523283e-04
## ASV8521      1.760315e-04  1.838732e-04  1.920386e-04  2.005386e-04
## ASV8581     -2.200337e-04 -2.303153e-04 -2.410679e-04 -2.523121e-04
## ASV9875     -3.765349e-05 -3.954552e-05 -4.153660e-05 -4.363223e-05
## ASV9986      1.458564e-04  1.527337e-04  1.599313e-04  1.674640e-04
## ASV2376      2.551825e-04  2.668770e-04  2.790861e-04  2.918303e-04
## ASV17535    -2.200208e-04 -2.303011e-04 -2.410524e-04 -2.522951e-04
## ASV14330    -2.126832e-04 -2.222774e-04 -2.322798e-04 -2.427055e-04
## ASV1333     -4.406027e-04 -4.599409e-04 -4.800538e-04 -5.009661e-04
## ASV2498      1.052601e-04  1.103520e-04  1.156920e-04  1.212921e-04
## ASV6352     -8.682678e-05 -9.064262e-05 -9.461163e-05 -9.873866e-05
## ASV8601     -1.087560e-04 -1.136420e-04 -1.187340e-04 -1.240396e-04
## ASV9776     -8.113297e-05 -8.465122e-05 -8.830590e-05 -9.210082e-05
## ASV1916      1.885619e-04  1.970737e-04  2.059489e-04  2.152012e-04
## ASV1555      2.379120e-05  2.499629e-05  2.626514e-05  2.760132e-05
## ASV2499      2.970704e-04  3.109011e-04  3.253605e-04  3.404757e-04
## ASV0703      2.447608e-04  2.560755e-04  2.678975e-04  2.802479e-04
## ASV2047      3.245928e-04  3.394718e-04  3.550058e-04  3.712214e-04
## ASV5492     -2.207409e-04 -2.310920e-04 -2.419209e-04 -2.532491e-04
## ASV6549     -2.253960e-05 -2.366184e-05 -2.484218e-05 -2.608383e-05
## ASV7757     -7.844590e-05 -8.231964e-05 -8.639024e-05 -9.066814e-05
## ASV0173     -1.871545e-06 -2.047432e-06 -2.239528e-06 -2.449280e-06
## ASV1248     -6.677588e-05 -6.972401e-05 -7.279115e-05 -7.598105e-05
## ASV6502      1.876239e-06  2.052534e-06  2.245070e-06  2.455297e-06
## ASV9844      1.875939e-06  2.052191e-06  2.244677e-06  2.454848e-06
## ASV3903      1.406469e-04  1.472630e-04  1.541861e-04  1.614302e-04
## ASV8199      1.866550e-06  2.041883e-06  2.233361e-06  2.442425e-06
## ASV3309     -9.881329e-06 -1.029513e-05 -1.072323e-05 -1.116579e-05
## ASV5826     -3.239963e-05 -3.399535e-05 -3.567138e-05 -3.743186e-05
## ASV1480     -2.953247e-04 -3.091798e-04 -3.236747e-04 -3.388381e-04
## ASV3090      6.273859e-05  6.558347e-05  6.855070e-05  7.164492e-05
## ASV0758     -1.792458e-04 -1.871145e-04 -1.952986e-04 -2.038079e-04
## ASV0811     -5.406127e-05 -5.644669e-05 -5.892878e-05 -6.151070e-05
## ASV2653      1.463671e-04  1.533097e-04  1.605794e-04  1.681913e-04
## ASV0978      1.513313e-04  1.585263e-04  1.660610e-04  1.739509e-04
## ASV6640     -3.062651e-04 -3.203633e-04 -3.350877e-04 -3.504642e-04
## ASV3423     -1.402374e-05 -1.483806e-05 -1.570487e-05 -1.662792e-05
## ASV0617      3.065795e-04  3.200039e-04  3.339654e-04  3.484811e-04
## ASV14947    -3.095509e-04 -3.239044e-04 -3.389045e-04 -3.545785e-04
## ASV18367    -1.696694e-04 -1.778049e-04 -1.863309e-04 -1.952658e-04
## ASV4574      2.368296e-04  2.472585e-04  2.581071e-04  2.693887e-04
## ASV10514    -1.652537e-04 -1.729978e-04 -1.810983e-04 -1.895708e-04
## ASV11779    -8.268433e-05 -8.695529e-05 -9.145747e-05 -9.620395e-05
## ASV7528     -2.675770e-04 -2.801205e-04 -2.932411e-04 -3.069641e-04
## ASV13153    -1.539330e-04 -1.612049e-04 -1.688166e-04 -1.767836e-04
## ASV7858     -1.366960e-04 -1.431524e-04 -1.499105e-04 -1.569839e-04
## ASV8722      4.668870e-05  4.861050e-05  5.059688e-05  5.264863e-05
## ASV6585     -3.088904e-04 -3.232086e-04 -3.381713e-04 -3.538057e-04
## ASV3311     -2.690664e-04 -2.809747e-04 -2.933676e-04 -3.062608e-04
## ASV2469      4.450082e-06  4.760361e-06  5.093246e-06  5.450342e-06
## ASV11340    -1.336232e-04 -1.395823e-04 -1.457886e-04 -1.522507e-04
## ASV1718      2.525816e-05  2.636001e-05  2.750493e-05  2.869414e-05
## ASV2117     -3.065123e-04 -3.207669e-04 -3.356676e-04 -3.512421e-04
## ASV8252     -2.178154e-04 -2.278891e-04 -2.384147e-04 -2.494113e-04
## ASV8533      4.278595e-05  4.475027e-05  4.680139e-05  4.894285e-05
## ASV9507      3.297324e-05  3.437096e-05  3.581973e-05  3.732064e-05
## ASV0706      1.550014e-04  1.624065e-04  1.701660e-04  1.782969e-04
## ASV10312    -2.177959e-04 -2.278678e-04 -2.383914e-04 -2.493857e-04
## ASV10696    -2.177780e-04 -2.278482e-04 -2.383699e-04 -2.493622e-04
## ASV11203    -2.177601e-04 -2.278286e-04 -2.383484e-04 -2.493387e-04
## ASV12147    -5.216137e-05 -5.468559e-05 -5.733349e-05 -6.011124e-05
## ASV4602     -1.368014e-05 -1.444441e-05 -1.525542e-05 -1.611628e-05
## ASV5568      1.144707e-05  1.204621e-05  1.267849e-05  1.334585e-05
## ASV6777      2.787980e-04  2.917125e-04  3.052082e-04  3.193096e-04
## ASV8749     -2.453856e-04 -2.566094e-04 -2.683250e-04 -2.805521e-04
## ASV4780      4.201906e-05  4.380267e-05  4.565137e-05  4.756651e-05
## ASV10116    -4.126801e-05 -4.315173e-05 -4.511799e-05 -4.717013e-05
## ASV2907      2.375019e-04  2.484429e-04  2.598700e-04  2.718032e-04
## ASV5165      3.091872e-04  3.238914e-04  3.392927e-04  3.554239e-04
## ASV6061      1.726948e-04  1.805469e-04  1.887389e-04  1.972840e-04
## ASV8082     -1.072493e-04 -1.122170e-04 -1.174086e-04 -1.228335e-04
## ASV7696     -1.092262e-04 -1.142927e-04 -1.195882e-04 -1.251223e-04
## ASV0550      2.190446e-05  2.283888e-05  2.380869e-05  2.481490e-05
## ASV7745      1.397721e-04  1.464635e-04  1.534758e-04  1.608245e-04
## ASV3607     -3.061958e-06 -3.159568e-06 -3.257500e-06 -3.355402e-06
## ASV3877     -2.126277e-04 -2.222212e-04 -2.322236e-04 -2.426499e-04
## ASV7667     -9.692659e-05 -1.012405e-04 -1.057329e-04 -1.104103e-04
## ASV9293     -8.117553e-05 -8.498358e-05 -8.896685e-05 -9.313302e-05
## ASV11653    -2.125978e-04 -2.221886e-04 -2.321879e-04 -2.426110e-04
## ASV12850     3.407293e-05  3.583148e-05  3.768436e-05  3.963675e-05
## ASV13104     4.012899e-05  4.181829e-05  4.356779e-05  4.537856e-05
## ASV14208    -2.125845e-04 -2.221741e-04 -2.321721e-04 -2.425938e-04
## ASV1552      1.958015e-04  2.050952e-04  2.148273e-04  2.250182e-04
## ASV2501      1.329448e-04  1.388475e-04  1.449929e-04  1.513893e-04
## ASV2893      2.643546e-04  2.766160e-04  2.894296e-04  3.028187e-04
## ASV3084      1.002327e-04  1.047329e-04  1.094233e-04  1.143108e-04
## ASV3599      1.347227e-04  1.407350e-04  1.469968e-04  1.535168e-04
## ASV3868     -2.125852e-04 -2.221750e-04 -2.321731e-04 -2.425950e-04
## ASV3917     -2.862063e-04 -2.992136e-04 -3.127836e-04 -3.269382e-04
## ASV5695      5.349756e-05  5.609085e-05  5.881112e-05  6.166460e-05
## ASV0131      2.843974e-05  2.947963e-05  3.054157e-05  3.162437e-05
## ASV2847      2.578374e-04  2.693097e-04  2.812555e-04  2.936912e-04
## ASV6875     -2.123868e-04 -2.220704e-04 -2.321754e-04 -2.427184e-04
## ASV1547     -4.388431e-04 -4.586935e-04 -4.793935e-04 -5.009749e-04
## ASV1501     -2.759199e-04 -2.885504e-04 -3.017355e-04 -3.154977e-04
## ASV3876      3.073360e-04  3.214843e-04  3.362608e-04  3.516911e-04
## ASV3456     -3.073108e-04 -3.214568e-04 -3.362307e-04 -3.516581e-04
## ASV1194      2.897865e-04  3.031182e-04  3.170410e-04  3.315790e-04
## ASV2135     -3.710614e-04 -3.883227e-04 -4.063672e-04 -4.252287e-04
## ASV1352      3.072410e-04  3.213804e-04  3.361470e-04  3.515666e-04
## ASV3208      3.494944e-04  3.656004e-04  3.824229e-04  3.999916e-04
## ASV1164      2.816526e-06  3.077843e-06  3.362458e-06  3.672331e-06
## ASV3492      1.462533e-04  1.532737e-04  1.606327e-04  1.683465e-04
## ASV1601      1.690951e-04  1.768691e-04  1.849874e-04  1.934640e-04
## ASV5347     -2.169777e-04 -2.267651e-04 -2.369693e-04 -2.476059e-04
## ASV0293      1.632784e-04  1.708065e-04  1.786697e-04  1.868819e-04
## ASV1509      2.817382e-04  2.946789e-04  3.081909e-04  3.222972e-04
## ASV2801      4.099837e-05  4.283426e-05  4.474735e-05  4.674045e-05
## ASV2873     -6.531694e-05 -6.841826e-05 -7.166645e-05 -7.506843e-05
## ASV2162     -4.396592e-05 -4.594545e-05 -4.800903e-05 -5.015980e-05
## ASV0462      1.706805e-04  1.781254e-04  1.858649e-04  1.939081e-04
## ASV5367     -2.664213e-04 -2.788040e-04 -2.917471e-04 -3.052747e-04
## ASV2715      3.333161e-04  3.485021e-04  3.643479e-04  3.808792e-04
## ASV0371      4.092125e-04  4.274779e-04  4.465053e-04  4.663219e-04
## ASV8090     -2.823505e-04 -2.951448e-04 -3.084885e-04 -3.224026e-04
## ASV6320     -2.201712e-04 -2.304688e-04 -2.412392e-04 -2.525035e-04
## ASV2562      2.312476e-04  2.420903e-04  2.534329e-04  2.652975e-04
## ASV1505     -3.244115e-04 -3.395089e-04 -3.552912e-04 -3.717879e-04
## ASV4924     -2.488926e-04 -2.602586e-04 -2.721206e-04 -2.844980e-04
## ASV1437      2.780934e-04  2.908899e-04  3.042544e-04  3.182100e-04
## ASV3816     -1.859274e-05 -1.922965e-05 -1.987578e-05 -2.052993e-05
## ASV1969     -1.345179e-04 -1.410206e-04 -1.478370e-04 -1.549817e-04
## ASV3146      1.479452e-04  1.545320e-04  1.613910e-04  1.685318e-04
## ASV0321     -1.601262e-04 -1.673358e-04 -1.748520e-04 -1.826862e-04
## ASV1020      3.226165e-04  3.371940e-04  3.523946e-04  3.682417e-04
## ASV4138      2.247501e-05  2.365366e-05  2.489770e-05  2.621096e-05
## ASV0329     -1.784185e-04 -1.866798e-04 -1.953119e-04 -2.043300e-04
## ASV10647     3.204399e-05  3.359811e-05  3.522866e-05  3.693946e-05
## ASV3389      2.658415e-04  2.781051e-04  2.909155e-04  3.042953e-04
## ASV6880      1.433916e-04  1.495397e-04  1.559197e-04  1.625374e-04
## ASV2624     -3.567066e-05 -3.762129e-05 -3.968692e-05 -4.187487e-05
## ASV3686     -5.090753e-05 -5.385689e-05 -5.699237e-05 -6.032652e-05
## ASV12302    -2.215852e-04 -2.320153e-04 -2.429304e-04 -2.543525e-04
## ASV1184      2.715480e-04  2.839643e-04  2.969237e-04  3.104478e-04
## ASV3533     -1.164560e-04 -1.214891e-04 -1.267147e-04 -1.321379e-04
## ASV1735      6.485283e-05  6.763921e-05  7.053076e-05  7.353008e-05
## ASV0483     -1.257499e-04 -1.316715e-04 -1.378680e-04 -1.443516e-04
## ASV0928     -2.500426e-04 -2.616619e-04 -2.738075e-04 -2.865019e-04
## ASV12254    -2.194149e-04 -2.296380e-04 -2.403266e-04 -2.515010e-04
## ASV16025    -2.193967e-04 -2.296180e-04 -2.403048e-04 -2.514771e-04
## ASV3070     -2.193785e-04 -2.295981e-04 -2.402830e-04 -2.514532e-04
## ASV1850      5.154287e-05  5.403056e-05  5.663909e-05  5.937431e-05
## ASV8946     -2.154186e-04 -2.252622e-04 -2.355358e-04 -2.462565e-04
## ASV1536      1.806043e-04  1.888259e-04  1.974037e-04  2.063514e-04
## ASV4151      2.717614e-04  2.840690e-04  2.969049e-04  3.102890e-04
## ASV4585      3.649186e-04  3.814405e-04  3.986707e-04  4.166358e-04
## ASV4921     -8.827068e-05 -9.220630e-05 -9.630396e-05 -1.005690e-04
## ASV6172      2.153703e-04  2.252094e-04  2.354781e-04  2.461934e-04
## ASV6375     -2.153528e-04 -2.251902e-04 -2.354572e-04 -2.461706e-04
## ASV6501      2.450444e-04  2.559407e-04  2.672869e-04  2.790988e-04
## ASV17095    -2.153391e-04 -2.251753e-04 -2.354408e-04 -2.461527e-04
## ASV3679     -2.153216e-04 -2.251561e-04 -2.354199e-04 -2.461298e-04
## ASV5750      2.153041e-04  2.251370e-04  2.353990e-04  2.461069e-04
## ASV5922     -2.152866e-04 -2.251179e-04 -2.353781e-04 -2.460841e-04
## ASV7323     -2.152691e-04 -2.250987e-04 -2.353572e-04 -2.460612e-04
## ASV8515     -3.029757e-06 -3.208246e-06 -3.397529e-06 -3.598210e-06
## ASV8753     -2.152514e-04 -2.250794e-04 -2.353360e-04 -2.460381e-04
## ASV9197      1.479143e-04  1.547068e-04  1.617989e-04  1.692028e-04
## ASV1778      4.020945e-05  4.223005e-05  4.435610e-05  4.659336e-05
## ASV1241      2.777449e-04  2.903168e-04  3.034274e-04  3.170971e-04
## ASV1717      2.170687e-04  2.269942e-04  2.373546e-04  2.481671e-04
## ASV1112      2.492661e-04  2.603317e-04  2.718516e-04  2.838411e-04
## ASV3994      2.922535e-04  3.057686e-04  3.198885e-04  3.346382e-04
## ASV5511     -2.163460e-04 -2.262785e-04 -2.366494e-04 -2.474765e-04
## ASV8706      1.573124e-04  1.647663e-04  1.725708e-04  1.807424e-04
## ASV3049     -2.163318e-04 -2.262629e-04 -2.366323e-04 -2.474578e-04
## ASV4332      1.389872e-04  1.454961e-04  1.523039e-04  1.594237e-04
## ASV7411      2.452459e-04  2.562269e-04  2.676672e-04  2.795832e-04
## ASV7475     -2.163245e-04 -2.262549e-04 -2.366236e-04 -2.474483e-04
## ASV8988     -2.163068e-04 -2.262355e-04 -2.366024e-04 -2.474252e-04
## ASV0688     -4.619038e-04 -4.825900e-04 -5.041425e-04 -5.265922e-04
## ASV1946      1.247107e-04  1.301040e-04  1.357059e-04  1.415221e-04
## ASV3150      3.595062e-04  3.758225e-04  3.928415e-04  4.105900e-04
## ASV3508      1.756596e-04  1.834089e-04  1.914715e-04  1.998574e-04
## ASV3863     -2.162943e-04 -2.262218e-04 -2.365874e-04 -2.474087e-04
## ASV4544      1.699995e-04  1.774897e-04  1.852818e-04  1.933854e-04
## ASV4567      3.902525e-04  4.081109e-04  4.267526e-04  4.462088e-04
## ASV4855     -2.162759e-04 -2.262018e-04 -2.365655e-04 -2.473847e-04
## ASV4872      2.885060e-04  3.015479e-04  3.151465e-04  3.293228e-04
## ASV4881      2.078536e-04  2.176226e-04  2.278440e-04  2.385383e-04
## ASV5283      2.162615e-04  2.261860e-04  2.365482e-04  2.473659e-04
## ASV5302      2.554049e-04  2.670393e-04  2.791813e-04  2.918511e-04
## ASV5909      2.169794e-04  2.268944e-04  2.372425e-04  2.480408e-04
## ASV5933      1.619817e-04  1.694094e-04  1.771640e-04  1.852585e-04
## ASV6019      2.396653e-04  2.502446e-04  2.612532e-04  2.727050e-04
## ASV6043      9.635397e-05  1.009130e-04  1.056859e-04  1.106823e-04
## ASV6908      2.710760e-04  2.834683e-04  2.964027e-04  3.099006e-04
## ASV7245     -2.162711e-04 -2.261965e-04 -2.365597e-04 -2.473784e-04
## ASV7249     -2.162534e-04 -2.261772e-04 -2.365385e-04 -2.473552e-04
## ASV8349      7.288087e-05  7.628194e-05  7.983826e-05  8.355656e-05
## ASV7310     -2.162389e-04 -2.261613e-04 -2.365212e-04 -2.473363e-04
## ASV1893      1.676163e-04  1.752025e-04  1.831148e-04  1.913658e-04
## ASV2354      1.288137e-04  1.344019e-04  1.402082e-04  1.462391e-04
## ASV3435     -3.610447e-05 -3.763596e-05 -3.922346e-05 -4.086818e-05
## ASV0480      3.360087e-04  3.517316e-04  3.681749e-04  3.853700e-04
## ASV0955     -1.167153e-04 -1.221740e-04 -1.278834e-04 -1.338545e-04
## ASV10000     6.560541e-05  6.828848e-05  7.106013e-05  7.392131e-05
## ASV7215     -1.399114e-04 -1.464896e-04 -1.533721e-04 -1.605725e-04
## ASV10423    -3.061192e-04 -3.201521e-04 -3.348024e-04 -3.500949e-04
## ASV6008     -1.635480e-04 -1.710650e-04 -1.789144e-04 -1.871098e-04
## ASV9330     -3.060825e-04 -3.201120e-04 -3.347586e-04 -3.500469e-04
## ASV6051      3.060575e-04  3.200847e-04  3.347287e-04  3.500142e-04
## ASV1675      2.023236e-04  2.115853e-04  2.212532e-04  2.313435e-04
## ASV2043      1.312393e-04  1.374293e-04  1.439081e-04  1.506888e-04
## ASV3634      1.235159e-04  1.294583e-04  1.356888e-04  1.422217e-04
## ASV4077     -3.060455e-04 -3.200716e-04 -3.347144e-04 -3.499986e-04
## ASV4754      1.480862e-04  1.547842e-04  1.617686e-04  1.690504e-04
## ASV6095      3.510822e-04  3.668517e-04  3.832868e-04  4.004118e-04
## ASV6288      2.597196e-04  2.714681e-04  2.837190e-04  2.964910e-04
## ASV6507     -3.060302e-04 -3.200548e-04 -3.346961e-04 -3.499786e-04
## ASV8905      1.554055e-04  1.624326e-04  1.697606e-04  1.774006e-04
## ASV9728     -3.060095e-04 -3.200322e-04 -3.346713e-04 -3.499515e-04
## ASV11144    -3.059845e-04 -3.200049e-04 -3.346415e-04 -3.499189e-04
## ASV1615     -1.231216e-04 -1.288413e-04 -1.348195e-04 -1.410669e-04
## ASV2709     -3.732192e-04 -3.902793e-04 -4.080855e-04 -4.266671e-04
## ASV3003      2.960313e-04  3.097472e-04  3.240809e-04  3.390583e-04
## ASV5163     -2.820220e-04 -2.949297e-04 -3.084033e-04 -3.224652e-04
## ASV6622      1.981629e-04  2.074198e-04  2.171005e-04  2.272235e-04
## ASV1076     -2.921426e-04 -3.055900e-04 -3.196342e-04 -3.342998e-04
## ASV7895      6.917238e-05  7.221503e-05  7.537946e-05  7.866941e-05
## ASV10577    -2.214897e-04 -2.319113e-04 -2.428173e-04 -2.542296e-04
## ASV1272      2.214711e-04  2.318910e-04  2.427950e-04  2.542052e-04
## ASV2492     -1.095601e-04 -1.150851e-04 -1.209004e-04 -1.270222e-04
## ASV5195      2.660050e-04  2.782941e-04  2.911332e-04  3.045453e-04
## ASV5267      1.602000e-04  1.674419e-04  1.749926e-04  1.828637e-04
## ASV6317      2.264629e-04  2.370378e-04  2.480959e-04  2.596584e-04
## ASV2296      8.139850e-05  8.517411e-05  8.912081e-05  9.324603e-05
## ASV2290     -1.996027e-04 -2.085768e-04 -2.179301e-04 -2.276766e-04
## ASV3726      1.734843e-04  1.816807e-04  1.902607e-04  1.992417e-04
## ASV1169      1.467445e-04  1.534301e-04  1.604064e-04  1.676847e-04
## ASV0189     -1.405326e-04 -1.471923e-04 -1.541654e-04 -1.614665e-04
## ASV2729      5.319466e-04  5.568986e-04  5.830006e-04  6.103035e-04
## ASV3469      1.209760e-04  1.265955e-04  1.324694e-04  1.386085e-04
## ASV0762     -2.882260e-04 -3.011838e-04 -3.146886e-04 -3.287601e-04
## ASV9001     -2.666337e-04 -2.782655e-04 -2.903593e-04 -3.029297e-04
## ASV14604    -2.146222e-04 -2.243931e-04 -2.345877e-04 -2.452224e-04
## ASV7439      6.354142e-05  6.665689e-05  6.992867e-05  7.336486e-05
## ASV8625     -2.146078e-04 -2.243774e-04 -2.345706e-04 -2.452037e-04
## ASV11553     4.213573e-05  4.423132e-05  4.643465e-05  4.875152e-05
## ASV14440     5.436836e-06  5.345510e-06  5.219814e-06  5.055756e-06
## ASV16106    -2.145926e-04 -2.243608e-04 -2.345524e-04 -2.451838e-04
## ASV16110    -2.145752e-04 -2.243418e-04 -2.345316e-04 -2.451611e-04
## ASV2229      3.786603e-04  3.956060e-04  4.132606e-04  4.316492e-04
## ASV3854     -2.076622e-04 -2.171184e-04 -2.269848e-04 -2.372773e-04
## ASV5512     -2.145519e-04 -2.243162e-04 -2.345037e-04 -2.451305e-04
## ASV5939      2.881621e-04  3.013840e-04  3.151888e-04  3.295999e-04
## ASV6676     -1.483068e-04 -1.550614e-04 -1.621091e-04 -1.694612e-04
## ASV8381     -2.145127e-04 -2.242734e-04 -2.344568e-04 -2.450794e-04
## ASV2735      2.730752e-04  2.856658e-04  2.988167e-04  3.125508e-04
## ASV9816     -2.145010e-04 -2.242606e-04 -2.344429e-04 -2.450642e-04
## ASV1382      9.649822e-05  1.007420e-04  1.051567e-04  1.097478e-04
## ASV1408     -2.152873e-04 -2.251248e-04 -2.353926e-04 -2.461080e-04
## ASV4902      1.368931e-04  1.435233e-04  1.504786e-04  1.577752e-04
## ASV5600      1.664685e-04  1.740514e-04  1.819639e-04  1.902190e-04
## ASV0815     -4.654674e-05 -4.856547e-05 -5.066247e-05 -5.283992e-05
## ASV11867    -2.152784e-04 -2.251151e-04 -2.353821e-04 -2.460965e-04
## ASV16064    -2.152609e-04 -2.250960e-04 -2.353612e-04 -2.460736e-04
## ASV2250      2.704582e-04  2.829536e-04  2.960084e-04  3.096458e-04
## ASV2417      6.336086e-05  6.644068e-05  6.967215e-05  7.306284e-05
## ASV2807      3.513081e-04  3.669761e-04  3.832951e-04  4.002880e-04
## ASV3224     -2.152207e-04 -2.250520e-04 -2.353132e-04 -2.460213e-04
## ASV4115     -2.152032e-04 -2.250329e-04 -2.352923e-04 -2.459984e-04
## ASV4876      3.523454e-05  3.680328e-05  3.843616e-05  4.013520e-05
## ASV5291      2.094771e-04  2.189021e-04  2.287253e-04  2.389612e-04
## ASV5834      1.016242e-04  1.062727e-04  1.111245e-04  1.161876e-04
## ASV6896      2.363203e-05  2.462046e-05  2.564340e-05  2.670138e-05
## ASV7292     -2.151923e-04 -2.250209e-04 -2.352792e-04 -2.459841e-04
## ASV7924      1.237640e-04  1.295201e-04  1.355370e-04  1.418261e-04
## ASV0710      2.846017e-04  2.974813e-04  3.109120e-04  3.249144e-04
## ASV1925      2.477007e-04  2.588165e-04  2.703996e-04  2.824668e-04
## ASV4247     -2.151732e-04 -2.250002e-04 -2.352565e-04 -2.459593e-04
## ASV4549     -2.151557e-04 -2.249810e-04 -2.352356e-04 -2.459364e-04
## ASV4076      1.800996e-04  1.883409e-04  1.969442e-04  2.059239e-04
## ASV7063      1.749943e-04  1.830869e-04  1.915415e-04  2.003730e-04
## ASV1487      1.855140e-04  1.937493e-04  2.023227e-04  2.112457e-04
## ASV1405      7.709101e-05  8.078369e-05  8.465355e-05  8.870905e-05
## ASV3851      1.911600e-04  2.001324e-04  2.095183e-04  2.193360e-04
## ASV0896      5.830647e-05  6.100920e-05  6.383380e-05  6.678546e-05
## ASV5581      2.781426e-04  2.912655e-04  3.050011e-04  3.193775e-04
## ASV7053     -9.158270e-05 -9.579296e-05 -1.001898e-04 -1.047807e-04
## ASV7171     -2.198515e-04 -2.301175e-04 -2.408533e-04 -2.520796e-04
## ASV4017     -3.009519e-04 -3.149388e-04 -3.295594e-04 -3.448410e-04
## ASV5846      1.853635e-05  1.892617e-05  1.929185e-05  1.962881e-05
## ASV0203      1.870791e-06  1.812521e-06  1.741171e-06  1.655620e-06
## ASV13271     3.406787e-05  3.546091e-05  3.690003e-05  3.838571e-05
## ASV9487      1.375324e-04  1.433203e-04  1.493175e-04  1.555285e-04
## ASV2056     -3.083129e-04 -3.225771e-04 -3.374813e-04 -3.530522e-04
## ASV16933    -3.034104e-04 -3.172016e-04 -3.315897e-04 -3.465977e-04
## ASV0360      1.317491e-04  1.375842e-04  1.436585e-04  1.499802e-04
## ASV1798     -1.973238e-04 -2.062861e-04 -2.156355e-04 -2.253867e-04
## ASV17286    -2.196155e-04 -2.298569e-04 -2.405655e-04 -2.517616e-04
## ASV8175     -2.195973e-04 -2.298370e-04 -2.405437e-04 -2.517377e-04
## ASV6679      2.324195e-04  2.429851e-04  2.540073e-04  2.655036e-04
## ASV6776      1.121038e-04  1.170892e-04  1.222798e-04  1.276825e-04
## ASV9062     -2.195807e-04 -2.298189e-04 -2.405238e-04 -2.517160e-04
## ASV9564     -1.948819e-05 -2.050722e-05 -2.158318e-05 -2.271953e-05
## ASV6431     -2.195612e-04 -2.297974e-04 -2.405003e-04 -2.516902e-04
## ASV9940      8.953010e-05  9.360229e-05  9.785030e-05  1.022808e-04
## ASV7001     -3.038506e-04 -3.176744e-04 -3.320969e-04 -3.471412e-04
## ASV3044      3.431141e-04  3.587228e-04  3.750080e-04  3.919963e-04
## ASV6684      1.269279e-04  1.330349e-04  1.394376e-04  1.461504e-04
## ASV12278     2.020225e-06  2.206052e-06  2.408435e-06  2.628775e-06
## ASV3543     -2.029955e-04 -2.119291e-04 -2.212237e-04 -2.308910e-04
## ASV6397      2.016583e-06  2.202065e-06  2.404071e-06  2.623999e-06
## ASV9939      2.016266e-06  2.201703e-06  2.403658e-06  2.623528e-06
## ASV9432      1.773326e-04  1.857141e-04  1.944881e-04  2.036724e-04
## ASV2630     -2.205144e-04 -2.308506e-04 -2.416629e-04 -2.529724e-04
## ASV2175      2.894555e-04  3.030411e-04  3.172547e-04  3.321245e-04
## ASV4107      2.386574e-04  2.497489e-04  2.613426e-04  2.734598e-04
## ASV9172     -3.042577e-05 -3.200334e-05 -3.366776e-05 -3.542421e-05
## ASV3141      2.840726e-04  2.974792e-04  3.115122e-04  3.262003e-04
## ASV9010     -2.201479e-04 -2.304406e-04 -2.412054e-04 -2.524631e-04
## ASV2550      2.180251e-04  2.280265e-04  2.384686e-04  2.493691e-04
## ASV5845     -2.201354e-04 -2.304269e-04 -2.411903e-04 -2.524465e-04
## ASV3998      2.201171e-04  2.304068e-04  2.411684e-04  2.524225e-04
## ASV1389     -2.373311e-04 -2.476475e-04 -2.583698e-04 -2.695105e-04
## ASV0615     -2.484669e-04 -2.598675e-04 -2.717713e-04 -2.841988e-04
## ASV9127     -3.045625e-04 -3.184917e-04 -3.330310e-04 -3.482047e-04
## ASV1190      4.329422e-04  4.523464e-04  4.725647e-04  4.936264e-04
## ASV1211      1.091160e-04  1.141086e-04  1.193210e-04  1.247621e-04
## ASV1766     -3.131966e-04 -3.276179e-04 -3.426796e-04 -3.584079e-04
## ASV2337      2.180333e-04  2.281206e-04  2.386601e-04  2.496707e-04
## ASV2463      4.694385e-05  4.911359e-05  5.138028e-05  5.374792e-05
## ASV2806      1.626634e-04  1.699351e-04  1.775120e-04  1.854052e-04
## ASV0439     -2.807955e-04 -2.937222e-04 -3.072224e-04 -3.213196e-04
## ASV0839      2.675680e-04  2.801947e-04  2.934101e-04  3.072408e-04
## ASV14975    -2.180016e-04 -2.280858e-04 -2.386220e-04 -2.496290e-04
## ASV17712    -2.179836e-04 -2.280662e-04 -2.386005e-04 -2.496055e-04
## ASV2010     -2.480247e-05 -2.589144e-05 -2.702342e-05 -2.819964e-05
## ASV2041      1.142353e-04  1.197560e-04  1.255455e-04  1.316170e-04
## ASV2124     -2.812440e-04 -2.942906e-04 -3.079256e-04 -3.221737e-04
## ASV2585      3.891746e-04  4.070408e-04  4.256951e-04  4.451696e-04
## ASV3314      3.080873e-04  3.224654e-04  3.375002e-04  3.532206e-04
## ASV5051     -2.837866e-05 -2.952206e-05 -3.070038e-05 -3.191350e-05
## ASV10784     1.093667e-04  1.143452e-04  1.195397e-04  1.249587e-04
## ASV3279     -2.179403e-04 -2.280187e-04 -2.385486e-04 -2.495487e-04
## ASV9498      1.512735e-05  1.569238e-05  1.627064e-05  1.686162e-05
## ASV1059     -2.325915e-04 -2.435014e-04 -2.549149e-04 -2.668545e-04
## ASV13008    -2.179219e-04 -2.279986e-04 -2.385265e-04 -2.495245e-04
## ASV15803    -2.179039e-04 -2.279789e-04 -2.385050e-04 -2.495010e-04
## ASV2559     -2.114945e-04 -2.212817e-04 -2.315082e-04 -2.421923e-04
## ASV2623     -2.178865e-04 -2.279598e-04 -2.384841e-04 -2.494781e-04
## ASV2802     -1.224668e-04 -1.280608e-04 -1.338991e-04 -1.399916e-04
## ASV3799      3.346632e-04  3.499627e-04  3.659319e-04  3.825976e-04
## ASV5274     -3.861119e-07 -5.197016e-07 -6.697946e-07 -8.380166e-07
## ASV5835      1.344055e-04  1.407495e-04  1.473905e-04  1.543423e-04
## ASV7251     -2.178824e-04 -2.279553e-04 -2.384792e-04 -2.494727e-04
## ASV7616     -2.178645e-04 -2.279357e-04 -2.384577e-04 -2.494492e-04
## ASV9576     -2.178465e-04 -2.279161e-04 -2.384362e-04 -2.494257e-04
## ASV2870      1.596508e-04  1.670462e-04  1.747738e-04  1.828476e-04
## ASV3668     -1.403372e-04 -1.469044e-04 -1.537727e-04 -1.609554e-04
## ASV1633      1.061562e-04  1.111720e-04  1.164225e-04  1.219184e-04
## ASV6060     -4.242554e-06 -4.802858e-06 -5.420161e-06 -6.099509e-06
## ASV6305      1.097325e-04  1.148994e-04  1.203064e-04  1.259644e-04
## ASV5164      7.122610e-05  7.432736e-05  7.754981e-05  8.089688e-05
## ASV7252     -2.183428e-04 -2.284635e-04 -2.390401e-04 -2.500919e-04
## ASV9343      1.882788e-04  1.972543e-04  2.066574e-04  2.165084e-04
## ASV6835     -3.650751e-05 -3.814515e-05 -3.985153e-05 -4.162908e-05
## ASV1264      2.658255e-04  2.780000e-04  2.907101e-04  3.039772e-04
## ASV0591      2.337366e-05  2.411149e-05  2.485172e-05  2.559179e-05
## ASV1351      3.070664e-04  3.213135e-04  3.362034e-04  3.517637e-04
## ASV14224    -2.182984e-04 -2.284149e-04 -2.389869e-04 -2.500337e-04
## ASV1432     -2.182804e-04 -2.283952e-04 -2.389654e-04 -2.500101e-04
## ASV1559     -1.829324e-04 -1.914743e-04 -2.004066e-04 -2.097464e-04
## ASV2182      3.390168e-04  3.545321e-04  3.707281e-04  3.876318e-04
## ASV2304     -1.818293e-05 -1.896542e-05 -1.977759e-05 -2.062017e-05
## ASV6838     -1.874373e-06 -1.943827e-06 -2.014863e-06 -2.087417e-06
## ASV1125     -3.272394e-05 -3.431070e-05 -3.597539e-05 -3.772191e-05
## ASV17948    -2.182739e-04 -2.283880e-04 -2.389575e-04 -2.500015e-04
## ASV2609      1.925371e-04  2.015487e-04  2.109743e-04  2.208322e-04
## ASV6128     -1.790450e-04 -1.873894e-04 -1.961100e-04 -2.052221e-04
## ASV1338      4.307877e-05  4.476483e-05  4.649873e-05  4.828003e-05
## ASV2136      7.923055e-05  8.268808e-05  8.628219e-05  9.001703e-05
## ASV0929     -1.992268e-04 -2.083065e-04 -2.177815e-04 -2.276673e-04
## ASV3479      1.374176e-04  1.435905e-04  1.500232e-04  1.567250e-04
## ASV0886      3.667310e-04  3.836225e-04  4.012646e-04  4.196881e-04
## ASV1652      1.683834e-04  1.762041e-04  1.843787e-04  1.929226e-04
## ASV1160      3.043260e-04  3.184318e-04  3.331730e-04  3.485764e-04
## ASV5260     -5.755526e-05 -6.043503e-05 -6.346356e-05 -6.664881e-05
## ASV2352      3.732904e-04  3.899370e-04  4.072755e-04  4.253304e-04
## ASV0986     -1.480595e-04 -1.547455e-04 -1.617169e-04 -1.689844e-04
## ASV2021      2.456261e-04  2.568582e-04  2.685823e-04  2.808180e-04
## ASV16599    -2.014503e-04 -2.112867e-04 -2.216090e-04 -2.324412e-04
## ASV3497      1.867079e-04  1.954139e-04  2.045174e-04  2.140358e-04
## ASV1305      1.256721e-04  1.317357e-04  1.380927e-04  1.447569e-04
## ASV0927     -2.863010e-04 -2.986450e-04 -3.114620e-04 -3.247652e-04
## ASV0647     -9.417666e-05 -9.810533e-05 -1.021715e-04 -1.063775e-04
## ASV1832     -1.220917e-04 -1.276389e-04 -1.334260e-04 -1.394623e-04
## ASV1277      1.454371e-04  1.520976e-04  1.590507e-04  1.663078e-04
## ASV22332    -2.187946e-04 -2.289576e-04 -2.395805e-04 -2.506828e-04
## ASV10080    -2.759264e-05 -2.932664e-05 -3.117883e-05 -3.315757e-05
## ASV14157     2.941869e-05  3.086035e-05  3.237419e-05  3.396394e-05
## ASV15829    -2.187759e-04 -2.289371e-04 -2.395580e-04 -2.506581e-04
## ASV3609     -2.187578e-04 -2.289173e-04 -2.395363e-04 -2.506343e-04
## ASV5737      4.862428e-05  5.069145e-05  5.283440e-05  5.505473e-05
## ASV1474      1.595729e-04  1.670278e-04  1.748230e-04  1.829734e-04
## ASV2028      2.177712e-04  2.271623e-04  2.369136e-04  2.470349e-04
## ASV0818      2.629295e-04  2.750375e-04  2.876831e-04  3.008884e-04
## ASV0505     -2.275919e-04 -2.382151e-04 -2.493225e-04 -2.609350e-04
## ASV1813      1.072531e-04  1.119624e-04  1.168599e-04  1.219515e-04
## ASV0512      2.364287e-04  2.476362e-04  2.593678e-04  2.716470e-04
## ASV5374     -1.673890e-04 -1.751582e-04 -1.832791e-04 -1.917670e-04
## ASV2927     -2.137604e-05 -2.197142e-05 -2.255701e-05 -2.312906e-05
## ASV3596      1.641129e-04  1.714125e-04  1.790128e-04  1.869240e-04
## ASV1137      9.795614e-05  1.022386e-04  1.066897e-04  1.113144e-04
## ASV4541      2.491424e-06  2.722248e-06  2.973869e-06  3.248077e-06
## ASV9872     -2.491030e-06 -2.721798e-06 -2.973355e-06 -3.247491e-06
## ASV0359     -7.685836e-05 -8.025237e-05 -8.378382e-05 -8.745713e-05
## ASV0720     -1.312428e-04 -1.371071e-04 -1.432150e-04 -1.495752e-04
## ASV10545    -2.501567e-06 -2.733273e-06 -2.985846e-06 -3.261082e-06
## ASV13384    -2.501172e-06 -2.732821e-06 -2.985330e-06 -3.260493e-06
## ASV1456      5.722253e-06  5.964343e-06  6.215310e-06  6.475361e-06
## ASV1751     -2.501050e-06 -2.732667e-06 -2.985138e-06 -3.260255e-06
## ASV18419    -2.500655e-06 -2.732216e-06 -2.984622e-06 -3.259667e-06
## ASV2970      2.500260e-06  2.731764e-06  2.984107e-06  3.259078e-06
## ASV4215      1.707680e-04  1.786233e-04  1.868264e-04  1.953916e-04
## ASV4742      2.838079e-05  2.950378e-05  3.066007e-05  3.184958e-05
## ASV5017      5.383657e-05  5.621939e-05  5.869929e-05  6.127948e-05
## ASV5139     -2.497359e-06 -2.728528e-06 -2.980495e-06 -3.255047e-06
## ASV9133     -2.496965e-06 -2.728078e-06 -2.979980e-06 -3.254459e-06
## ASV9447     -2.496570e-06 -2.727627e-06 -2.979466e-06 -3.253872e-06
## ASV0842     -1.621757e-04 -1.691868e-04 -1.764693e-04 -1.840311e-04
## ASV12293     1.136274e-04  1.184250e-04  1.233973e-04  1.285482e-04
## ASV1965      2.053506e-04  2.149213e-04  2.249283e-04  2.353904e-04
## ASV2005      2.243758e-04  2.340999e-04  2.442016e-04  2.546918e-04
## ASV5335      1.670261e-04  1.743746e-04  1.820184e-04  1.899668e-04
## ASV6438     -2.522504e-06 -2.755874e-06 -3.010222e-06 -3.287348e-06
## ASV7798     -2.522106e-06 -2.755419e-06 -3.009702e-06 -3.286755e-06
## ASV2691     -2.311759e-04 -2.419086e-04 -2.531257e-04 -2.648478e-04
## ASV9958      1.890201e-04  1.975922e-04  2.065329e-04  2.158565e-04
## ASV1512      6.866250e-05  7.194275e-05  7.538027e-05  7.898267e-05
## ASV1226      3.104388e-04  3.246570e-04  3.395005e-04  3.549946e-04
## ASV2130     -5.476751e-04 -5.727315e-04 -5.988865e-04 -6.261838e-04
## ASV0874     -1.704468e-04 -1.782046e-04 -1.863006e-04 -1.947482e-04
## ASV5436     -2.437531e-04 -2.550209e-04 -2.667929e-04 -2.790900e-04
## ASV0383     -2.687252e-04 -2.805007e-04 -2.927453e-04 -3.054738e-04
## ASV1882      2.628096e-04  2.743416e-04  2.863364e-04  2.988090e-04
## ASV2471     -1.484745e-04 -1.552566e-04 -1.623351e-04 -1.697219e-04
## ASV4049     -2.109240e-04 -2.205115e-04 -2.305135e-04 -2.409458e-04
## ASV3014     -1.181075e-04 -1.233433e-04 -1.287933e-04 -1.344648e-04
## ASV0316     -4.226124e-04 -4.419611e-04 -4.621594e-04 -4.832412e-04
## ASV1621     -2.931967e-04 -3.064334e-04 -3.202345e-04 -3.346212e-04
## ASV13266    -2.152050e-04 -2.250324e-04 -2.352889e-04 -2.459915e-04
## ASV1635     -2.133967e-04 -2.231386e-04 -2.333057e-04 -2.439146e-04
## ASV2042      1.567492e-04  1.639156e-04  1.713960e-04  1.792027e-04
## ASV2317     -2.557863e-04 -2.674248e-04 -2.795676e-04 -2.922343e-04
## ASV3697      1.933247e-04  2.020078e-04  2.110570e-04  2.204858e-04
## ASV6404      3.557320e-04  3.716276e-04  3.881872e-04  4.054344e-04
## ASV15616     1.471149e-05  1.554546e-05  1.643093e-05  1.737135e-05
## ASV10783    -2.151676e-04 -2.249915e-04 -2.352442e-04 -2.459426e-04
## ASV6912     -1.614545e-04 -1.687783e-04 -1.764171e-04 -1.843832e-04
## ASV1561      4.364048e-04  4.560003e-04  4.764220e-04  4.976999e-04
## ASV4404      2.974455e-04  3.109944e-04  3.251319e-04  3.398811e-04
## ASV1110      2.184453e-04  2.283126e-04  2.386008e-04  2.493255e-04
## ASV2844     -7.392366e-05 -7.746319e-05 -8.117248e-05 -8.505965e-05
## ASV5224      2.180135e-04  2.279386e-04  2.382938e-04  2.490957e-04
## ASV6300     -2.185094e-04 -2.286450e-04 -2.392377e-04 -2.503069e-04
## ASV8078     -2.184914e-04 -2.286252e-04 -2.392160e-04 -2.502832e-04
## ASV9722      1.015510e-06  8.513735e-07  6.604026e-07  4.397029e-07
## ASV6911     -2.184732e-04 -2.286053e-04 -2.391942e-04 -2.502592e-04
## ASV5474     -4.471748e-05 -4.687674e-05 -4.914118e-05 -5.151595e-05
## ASV2761     -5.123231e-04 -5.356537e-04 -5.599972e-04 -5.853929e-04
## ASV5943     -1.423322e-04 -1.491705e-04 -1.563394e-04 -1.638552e-04
## ASV0600     -3.729299e-05 -3.863422e-05 -4.000127e-05 -4.139225e-05
## ASV0608     -4.596956e-04 -4.805294e-04 -5.022594e-04 -5.249199e-04
## ASV1586      1.107765e-04  1.156770e-04  1.207779e-04  1.260860e-04
## ASV0206     -5.107018e-04 -5.334371e-04 -5.571121e-04 -5.817589e-04
## ASV4042     -2.338344e-04 -2.445300e-04 -2.556942e-04 -2.673457e-04
## ASV5304     -6.956317e-06 -7.333134e-06 -7.731340e-06 -8.152156e-06
## ASV0949     -8.113769e-05 -8.534301e-05 -8.977759e-05 -9.445458e-05
## ASV1856      2.693416e-04  2.816855e-04  2.945722e-04  3.080233e-04
## ASV2584      3.183467e-05  3.317314e-05  3.455842e-05  3.599114e-05
## ASV2287     -1.329848e-05 -1.427720e-05 -1.533065e-05 -1.646441e-05
## ASV2364     -3.822223e-04 -3.996122e-04 -4.177560e-04 -4.366831e-04
## ASV11481    -3.045333e-04 -3.188037e-04 -3.337312e-04 -3.493449e-04
## ASV2906     -1.059508e-04 -1.109428e-04 -1.161668e-04 -1.216333e-04
## ASV0161     -1.267269e-04 -1.324835e-04 -1.384884e-04 -1.447511e-04
## ASV0062     -8.328797e-04 -8.707823e-04 -9.103279e-04 -9.515801e-04
## ASV3811     -1.969001e-04 -2.052718e-04 -2.139562e-04 -2.229616e-04
## ASV0225      3.295846e-05  3.414475e-05  3.535521e-05  3.658853e-05
## ASV4672     -2.670309e-04 -2.790297e-04 -2.915350e-04 -3.045655e-04
## ASV1607     -2.032511e-05 -2.129849e-05 -2.231709e-05 -2.338276e-05
## ASV3060      5.275905e-05  5.530193e-05  5.796848e-05  6.076477e-05
## ASV2275     -3.811152e-05 -3.985348e-05 -4.167156e-05 -4.356873e-05
## ASV5375      1.491433e-04  1.561714e-04  1.635268e-04  1.712244e-04
## ASV0352     -4.458897e-04 -4.666092e-04 -4.882668e-04 -5.109025e-04
## ASV1107      1.284986e-04  1.346258e-04  1.410429e-04  1.477633e-04
## ASV4887      1.160149e-04  1.210480e-04  1.262766e-04  1.317062e-04
## ASV2397     -5.852251e-05 -6.093993e-05 -6.343947e-05 -6.602225e-05
## ASV7541     -1.399072e-04 -1.462362e-04 -1.528357e-04 -1.597159e-04
## ASV7387     -3.059791e-04 -3.200121e-04 -3.346628e-04 -3.499560e-04
## ASV1355      2.805798e-04  2.935556e-04  3.071138e-04  3.212789e-04
## ASV1764     -1.463750e-04 -1.530030e-04 -1.599156e-04 -1.671236e-04
## ASV1960     -2.694491e-04 -2.810067e-04 -2.930044e-04 -3.054541e-04
## ASV0484     -5.172640e-05 -5.409339e-05 -5.656442e-05 -5.914368e-05
## ASV2487      8.370591e-05  8.717208e-05  9.075751e-05  9.446409e-05
## ASV0422      2.618547e-04  2.732450e-04  2.850843e-04  2.973864e-04
## ASV0081     -1.637787e-04 -1.715348e-04 -1.796557e-04 -1.881583e-04
## ASV1341     -1.413523e-04 -1.475339e-04 -1.539606e-04 -1.606400e-04
## ASV1001     -3.345058e-04 -3.492267e-04 -3.645402e-04 -3.804652e-04
## ASV0317     -8.091936e-05 -8.484415e-05 -8.895954e-05 -9.327457e-05
## ASV2728     -2.322615e-04 -2.428819e-04 -2.539676e-04 -2.655374e-04
## ASV0884     -2.979099e-04 -3.121335e-04 -3.270351e-04 -3.426469e-04
## ASV0464      6.378469e-05  6.721782e-05  7.084906e-05  7.469066e-05
## ASV2963      2.033931e-04  2.125073e-04  2.220048e-04  2.318994e-04
## ASV4608      9.187654e-05  9.607203e-05  1.004505e-04  1.050190e-04
## ASV3534      2.280629e-04  2.379087e-04  2.481331e-04  2.587465e-04
## ASV0291     -1.963962e-04 -2.052262e-04 -2.144288e-04 -2.240175e-04
## ASV0635     -2.833483e-04 -2.965828e-04 -3.104230e-04 -3.248955e-04
## ASV0867      2.281087e-04  2.389338e-04  2.502698e-04  2.621408e-04
## ASV1206     -2.647460e-05 -2.756754e-05 -2.869728e-05 -2.986425e-05
## ASV1230     -1.652324e-06 -1.808350e-06 -1.978836e-06 -2.165083e-06
## ASV1265      6.070155e-05  6.347452e-05  6.636886e-05  6.938943e-05
## ASV1291     -1.874112e-04 -1.961785e-04 -2.053481e-04 -2.149377e-04
## ASV1524      3.866199e-04  4.037853e-04  4.216560e-04  4.402559e-04
## ASV2153     -2.982921e-04 -3.115402e-04 -3.253340e-04 -3.396925e-04
## ASV2714      1.626562e-06  1.780256e-06  1.948209e-06  2.131702e-06
## ASV4246     -1.626300e-06 -1.779957e-06 -1.947866e-06 -2.131309e-06
## ASV0945      1.986507e-04  2.077273e-04  2.172003e-04  2.270853e-04
## ASV2380      4.614023e-04  4.819285e-04  5.033032e-04  5.255556e-04
## ASV0214     -6.920130e-05 -7.180585e-05 -7.447479e-05 -7.720645e-05
## ASV10461    -1.654166e-06 -1.810403e-06 -1.981126e-06 -2.167636e-06
## ASV4177      1.349456e-04  1.407200e-04  1.467115e-04  1.529256e-04
## ASV0237     -3.341642e-04 -3.497075e-04 -3.659555e-04 -3.829385e-04
## ASV11323    -3.774228e-04 -3.948444e-04 -4.130445e-04 -4.320556e-04
## ASV2232     -6.516298e-05 -6.802980e-05 -7.101182e-05 -7.411267e-05
## ASV0115     -1.216454e-04 -1.272114e-04 -1.330209e-04 -1.390834e-04
## ASV1171      5.650526e-05  5.875872e-05  6.108116e-05  6.347272e-05
## ASV1942      2.614545e-04  2.735326e-04  2.861516e-04  2.993341e-04
## ASV1889      2.619466e-05  2.733046e-05  2.851004e-05  2.973458e-05
## ASV0920      5.805068e-05  6.085058e-05  6.378649e-05  6.686501e-05
## ASV1805     -3.351709e-04 -3.504689e-04 -3.664345e-04 -3.830940e-04
## ASV1712      2.007825e-04  2.097931e-04  2.191818e-04  2.289622e-04
## ASV1458      2.949781e-04  3.080727e-04  3.217072e-04  3.359001e-04
## ASV1985      3.134572e-04  3.276648e-04  3.424841e-04  3.579385e-04
## ASV2960     -2.002722e-04 -2.087584e-04 -2.175588e-04 -2.266814e-04
## ASV5207     -6.093747e-05 -6.313201e-05 -6.537223e-05 -6.765590e-05
## ASV8548     -2.002538e-04 -2.087384e-04 -2.175372e-04 -2.266580e-04
## ASV0449     -1.200702e-04 -1.258108e-04 -1.318229e-04 -1.381188e-04
## ASV0609     -2.709821e-04 -2.832046e-04 -2.959462e-04 -3.092258e-04
## ASV1038      1.041186e-04  1.085141e-04  1.130689e-04  1.177865e-04
## ASV1145     -6.278539e-05 -6.535557e-05 -6.801173e-05 -7.075504e-05
## ASV15767    -2.002500e-04 -2.087344e-04 -2.175330e-04 -2.266535e-04
## ASV1630      2.824176e-04  2.948103e-04  3.077013e-04  3.211072e-04
## ASV1911      3.521629e-04  3.683250e-04  3.852004e-04  4.028181e-04
## ASV1950      2.546571e-04  2.657085e-04  2.771936e-04  2.891257e-04
## ASV2583      2.001975e-04  2.086773e-04  2.174709e-04  2.265860e-04
## ASV2853     -2.938241e-04 -3.068009e-04 -3.203066e-04 -3.343591e-04
## ASV2948      2.001662e-04  2.086432e-04  2.174338e-04  2.265457e-04
## ASV3116     -3.203038e-04 -3.342644e-04 -3.487773e-04 -3.638595e-04
## ASV3160     -1.721344e-04 -1.793088e-04 -1.867377e-04 -1.944265e-04
## ASV3354      2.117336e-04  2.214887e-04  2.316762e-04  2.423134e-04
## ASV3368      2.001230e-04  2.085963e-04  2.173829e-04  2.264905e-04
## ASV3464     -2.001079e-04 -2.085800e-04 -2.173652e-04 -2.264713e-04
## ASV3577      2.000929e-04  2.085637e-04  2.173475e-04  2.264521e-04
## ASV3746      2.618458e-04  2.731923e-04  2.849809e-04  2.972243e-04
## ASV3942      8.648225e-05  9.083721e-05  9.541863e-05  1.002386e-04
## ASV4000      2.000680e-04  2.085366e-04  2.173181e-04  2.264203e-04
## ASV4207      3.579170e-04  3.746604e-04  3.921716e-04  4.104844e-04
## ASV4261      2.000549e-04  2.085224e-04  2.173028e-04  2.264037e-04
## ASV4466      7.308501e-05  7.700582e-05  8.114786e-05  8.552393e-05
## ASV4487     -2.000448e-04 -2.085115e-04 -2.172910e-04 -2.263910e-04
## ASV4572     -1.514157e-04 -1.579625e-04 -1.647646e-04 -1.718295e-04
## ASV4718      2.000199e-04  2.084845e-04  2.172616e-04  2.263591e-04
## ASV4757     -2.000048e-04 -2.084682e-04 -2.172439e-04 -2.263399e-04
## ASV4929     -1.999898e-04 -2.084518e-04 -2.172262e-04 -2.263208e-04
## ASV5611     -1.999748e-04 -2.084355e-04 -2.172085e-04 -2.263016e-04
## ASV5614     -1.999598e-04 -2.084192e-04 -2.171909e-04 -2.262824e-04
## ASV5898      1.732545e-04  1.809760e-04  1.890172e-04  1.973891e-04
## ASV7627     -4.356172e-05 -4.498595e-05 -4.642429e-05 -4.787347e-05
## ASV3105     -1.099555e-04 -1.144484e-04 -1.190931e-04 -1.238922e-04
## ASV4762     -2.938815e-04 -3.068702e-04 -3.203893e-04 -3.344568e-04
## ASV5622      1.999216e-04  2.083778e-04  2.171459e-04  2.262337e-04
## ASV7129      2.601626e-04  2.718741e-04  2.840824e-04  2.968057e-04
## ASV12138    -1.999011e-04 -2.083555e-04 -2.171217e-04 -2.262074e-04
## ASV1687     -2.982200e-04 -3.116393e-04 -3.256298e-04 -3.402132e-04
## ASV2187      1.483578e-04  1.545662e-04  1.609977e-04  1.676573e-04
## ASV2204      3.019566e-04  3.154713e-04  3.295509e-04  3.442155e-04
## ASV2914      2.338801e-04  2.439220e-04  2.543482e-04  2.651693e-04
## ASV3297     -1.998466e-04 -2.082962e-04 -2.170573e-04 -2.261374e-04
## ASV3310     -2.566417e-04 -2.677659e-04 -2.793253e-04 -2.913329e-04
## ASV3677      1.504764e-05  1.632678e-05  1.771226e-05  1.921234e-05
## ASV4508      1.998143e-04  2.082613e-04  2.170194e-04  2.260963e-04
## ASV6236     -9.720674e-05 -1.009583e-04 -1.048152e-04 -1.087768e-04
## ASV6285      1.997932e-04  2.082383e-04  2.169946e-04  2.260695e-04
## ASV7576     -1.997782e-04 -2.082221e-04 -2.169769e-04 -2.260503e-04
## ASV7917     -1.997632e-04 -2.082058e-04 -2.169593e-04 -2.260312e-04
## ASV9353     -1.997482e-04 -2.081896e-04 -2.169416e-04 -2.260121e-04
## ASV1656      3.310690e-04  3.457951e-04  3.611298e-04  3.770942e-04
## ASV0280     -3.145760e-04 -3.292991e-04 -3.446987e-04 -3.608048e-04
## ASV4747      5.383847e-06  5.897856e-06  6.459893e-06  7.074312e-06
## ASV2108     -3.858263e-04 -4.037599e-04 -4.225066e-04 -4.421015e-04
## ASV0885      1.293817e-04  1.353426e-04  1.415689e-04  1.480715e-04
## ASV2538     -1.051119e-04 -1.097742e-04 -1.146274e-04 -1.196779e-04
## ASV0968      2.383856e-04  2.492193e-04  2.605210e-04  2.723089e-04
## ASV1229     -2.141683e-04 -2.238943e-04 -2.340396e-04 -2.446201e-04
## ASV13306    -2.141510e-04 -2.238754e-04 -2.340189e-04 -2.445975e-04
## ASV13952     1.309652e-04  1.366343e-04  1.425231e-04  1.486379e-04
## ASV14631     1.188727e-04  1.247064e-04  1.308336e-04  1.372695e-04
## ASV2119      2.533456e-04  2.643056e-04  2.756895e-04  2.875093e-04
## ASV2450      2.230655e-04  2.333469e-04  2.440865e-04  2.553031e-04
## ASV2656     -2.141441e-04 -2.238680e-04 -2.340108e-04 -2.445887e-04
## ASV2942     -1.554458e-05 -1.621667e-05 -1.691439e-05 -1.763839e-05
## ASV3302      1.910413e-04  1.996138e-04  2.085463e-04  2.178516e-04
## ASV6515      7.377221e-05  7.683090e-05  7.999558e-05  8.326806e-05
## ASV6674     -2.141300e-04 -2.238525e-04 -2.339939e-04 -2.445702e-04
## ASV7296     -7.930468e-05 -8.300960e-05 -8.688357e-05 -9.093387e-05
## ASV7903      1.176547e-04  1.227839e-04  1.281157e-04  1.336563e-04
## ASV7943     -2.141120e-04 -2.238328e-04 -2.339723e-04 -2.445466e-04
## ASV8864      1.578085e-04  1.643352e-04  1.710862e-04  1.780653e-04
## ASV9389      2.023261e-05  2.071273e-05  2.117451e-05  2.161387e-05
## ASV9869     -2.141000e-04 -2.238196e-04 -2.339578e-04 -2.445306e-04
## ASV1051      2.140827e-04  2.238007e-04  2.339372e-04  2.445081e-04
## ASV13035    -9.455675e-06 -9.817909e-06 -1.018946e-05 -1.057008e-05
## ASV15744     5.693780e-06  6.268183e-06  6.897489e-06  7.586712e-06
## ASV2526      2.268316e-05  2.352233e-05  2.438097e-05  2.525841e-05
## ASV1156      1.120679e-04  1.170929e-04  1.223289e-04  1.277838e-04
## ASV13562    -2.140728e-04 -2.237899e-04 -2.339254e-04 -2.444953e-04
## ASV1438      1.872198e-04  1.959524e-04  2.050843e-04  2.146329e-04
## ASV2268     -2.140639e-04 -2.237802e-04 -2.339149e-04 -2.444838e-04
## ASV2797      1.027806e-04  1.076849e-04  1.128234e-04  1.182072e-04
## ASV3744      2.385628e-04  2.495946e-04  2.611201e-04  2.731597e-04
## ASV8076     -2.306527e-04 -2.411392e-04 -2.520788e-04 -2.634888e-04
## ASV7055      9.891845e-05  1.037535e-04  1.088295e-04  1.141590e-04
## ASV7493     -1.954691e-04 -2.044099e-04 -2.137424e-04 -2.234820e-04
## ASV1201      4.757234e-04  4.972677e-04  5.197364e-04  5.431645e-04
## ASV5736     -4.115221e-04 -4.304951e-04 -4.503129e-04 -4.710104e-04
## ASV0558      1.990946e-04  2.084215e-04  2.181766e-04  2.283788e-04
## ASV14399    -2.852307e-04 -2.981269e-04 -3.115747e-04 -3.255949e-04
## ASV2992     -1.613504e-05 -1.685122e-05 -1.759672e-05 -1.837254e-05
## ASV4303     -2.095209e-04 -2.190279e-04 -2.289440e-04 -2.392847e-04
## ASV0565     -2.385789e-04 -2.494992e-04 -2.608998e-04 -2.727999e-04
## ASV0977     -3.556242e-04 -3.711186e-04 -3.872257e-04 -4.039643e-04
## ASV0140      1.791065e-04  1.872306e-04  1.957044e-04  2.045410e-04
## ASV14421    -2.148740e-04 -2.246702e-04 -2.348927e-04 -2.455581e-04
## ASV16909    -4.779177e-05 -5.007401e-05 -5.246506e-05 -5.497002e-05
## ASV3762     -2.148533e-04 -2.246476e-04 -2.348679e-04 -2.455310e-04
## ASV7141     -2.148359e-04 -2.246285e-04 -2.348471e-04 -2.455082e-04
## ASV3291      3.413499e-04  3.571855e-04  3.737356e-04  3.910308e-04
## ASV10440    -2.148157e-04 -2.246064e-04 -2.348229e-04 -2.454818e-04
## ASV10802     6.556423e-05  6.850611e-05  7.157163e-05  7.476522e-05
## ASV1698      3.583478e-05  3.758009e-05  3.941196e-05  4.133476e-05
## ASV2121      2.148028e-04  2.245923e-04  2.348075e-04  2.454650e-04
## ASV3549     -3.033212e-04 -3.171885e-04 -3.316625e-04 -3.467672e-04
## ASV6379      2.538189e-04  2.651085e-04  2.768641e-04  2.891018e-04
## ASV6824     -2.147643e-04 -2.245503e-04 -2.347616e-04 -2.454148e-04
## ASV8254      2.230395e-05  2.341436e-05  2.458176e-05  2.580918e-05
## ASV9951      9.449028e-05  9.896140e-05  1.036424e-04  1.085428e-04
## ASV1515     -8.996334e-05 -9.388336e-05 -9.795682e-05 -1.021881e-04
## ASV4327      6.552318e-05  6.851844e-05  7.164499e-05  7.490809e-05
## ASV0341     -9.963865e-05 -1.043572e-04 -1.092974e-04 -1.144692e-04
## ASV5562     -1.753112e-04 -1.835381e-04 -1.921452e-04 -2.011496e-04
## ASV1412      4.809637e-04  5.030260e-04  5.260618e-04  5.501104e-04
## ASV0154     -3.869418e-04 -4.048674e-04 -4.235999e-04 -4.431736e-04
## ASV3163     -1.791504e-04 -1.872538e-04 -1.957047e-04 -2.045163e-04
## ASV1782     -2.854375e-04 -2.984853e-04 -3.121032e-04 -3.263135e-04
## ASV3993     -3.098936e-05 -3.224215e-05 -3.353470e-05 -3.486723e-05
## ASV3164      1.373883e-04  1.434696e-04  1.497983e-04  1.563825e-04
## ASV1024      1.740900e-05  1.834426e-05  1.933381e-05  2.038110e-05
## ASV0771     -3.903935e-04 -4.078484e-04 -4.260311e-04 -4.449674e-04
## ASV2223     -1.726879e-04 -1.809066e-04 -1.895134e-04 -1.985262e-04
## ASV1638      6.457218e-04  6.749518e-04  7.054348e-04  7.372185e-04
## ASV0232     -1.895240e-04 -1.981366e-04 -2.071216e-04 -2.164933e-04
## ASV6771     -2.097877e-04 -2.196244e-04 -2.299133e-04 -2.406741e-04
## ASV4243     -8.262401e-05 -8.616092e-05 -8.983334e-05 -9.364528e-05
## ASV0162     -3.869614e-04 -4.046490e-04 -4.231089e-04 -4.423713e-04
## ASV0049      2.672946e-05  2.796944e-05  2.926557e-05  3.062027e-05
## ASV4697     -2.157753e-04 -2.256549e-04 -2.359682e-04 -2.467326e-04
## ASV12326     6.883093e-05  7.179745e-05  7.487732e-05  7.807355e-05
## ASV12586    -2.157605e-04 -2.256386e-04 -2.359504e-04 -2.467131e-04
## ASV1879      1.708171e-04  1.786533e-04  1.868344e-04  1.953744e-04
## ASV2864      4.708878e-04  4.926634e-04  5.154152e-04  5.391841e-04
## ASV3111     -1.254766e-04 -1.311997e-04 -1.371721e-04 -1.434035e-04
## ASV5633     -1.204026e-04 -1.258608e-04 -1.315536e-04 -1.374899e-04
## ASV5864      7.319206e-05  7.612732e-05  7.915402e-05  8.227252e-05
## ASV6364      1.037194e-04  1.086529e-04  1.138203e-04  1.192328e-04
## ASV1598      1.332140e-04  1.393411e-04  1.457410e-04  1.524249e-04
## ASV2649     -7.927729e-05 -8.315313e-05 -8.722178e-05 -9.149300e-05
## ASV4664      1.776495e-04  1.855936e-04  1.938700e-04  2.024904e-04
## ASV2654      2.991994e-04  3.128333e-04  3.270595e-04  3.419010e-04
## ASV6636     -2.075109e-05 -2.199166e-05 -2.331214e-05 -2.471787e-05
## ASV3334      2.228819e-04  2.334088e-04  2.444273e-04  2.559601e-04
## ASV0046     -3.972653e-04 -4.159274e-04 -4.354528e-04 -4.558800e-04
## ASV0661      4.021939e-04  4.202773e-04  4.391252e-04  4.587656e-04
## ASV0774      1.805278e-04  1.888142e-04  1.974658e-04  2.064974e-04
## ASV3815      2.157354e-04  2.254861e-04  2.356528e-04  2.462513e-04
## ASV0575      2.174012e-04  2.269875e-04  2.369623e-04  2.473384e-04
## ASV1953     -3.003801e-04 -3.141198e-04 -3.284609e-04 -3.434271e-04
## ASV0610      9.055083e-05  9.456406e-05  9.874183e-05  1.030897e-04
## ASV0245     -1.097225e-04 -1.147769e-04 -1.200561e-04 -1.255694e-04
## ASV3805     -1.588558e-04 -1.654034e-04 -1.721766e-04 -1.791792e-04
## ASV1182      4.483650e-04  4.693014e-04  4.911956e-04  5.140893e-04
## ASV1941      1.055174e-06  1.155843e-06  1.265980e-06  1.386455e-06
## ASV0080     -5.274757e-04 -5.515111e-04 -5.765908e-04 -6.027555e-04
## ASV1033      1.575404e-04  1.647574e-04  1.722916e-04  1.801558e-04
## ASV5330     -1.893765e-04 -1.979480e-04 -2.068863e-04 -2.162052e-04
## ASV9702     -2.898958e-04 -3.025006e-04 -3.156013e-04 -3.292131e-04
## ASV0358      7.786725e-06  7.993816e-06  8.196143e-06  8.392238e-06
## ASV2225      1.497430e-04  1.565308e-04  1.636101e-04  1.709920e-04
## ASV2606      6.868220e-06  7.043421e-06  7.213101e-06  7.375780e-06
## ASV3510     -2.332225e-04 -2.438955e-04 -2.550366e-04 -2.666643e-04
## ASV3069      7.993445e-05  8.330522e-05  8.679914e-05  9.041910e-05
## ASV3849      1.448988e-04  1.513411e-04  1.580486e-04  1.650300e-04
## ASV1810     -3.648415e-04 -3.808634e-04 -3.975302e-04 -4.148628e-04
## ASV2046      5.353367e-04  5.600059e-04  5.857726e-04  6.126817e-04
## ASV2451     -6.480151e-05 -6.807914e-05 -7.152838e-05 -7.515849e-05
## ASV4047      2.796700e-04  2.923819e-04  3.056438e-04  3.194770e-04
## ASV7402     -2.208141e-04 -2.311522e-04 -2.419641e-04 -2.532706e-04
## ASV8250      2.710905e-04  2.837063e-04  2.968949e-04  3.106811e-04
## ASV3468      2.329085e-04  2.434879e-04  2.545242e-04  2.660349e-04
## ASV3521      4.788713e-04  5.008664e-04  5.238341e-04  5.478140e-04
## ASV6363     -1.626084e-04 -1.702916e-04 -1.783331e-04 -1.867490e-04
## ASV6444      1.087627e-04  1.139034e-04  1.192858e-04  1.249214e-04
## ASV8231      1.258845e-04  1.315375e-04  1.374292e-04  1.435681e-04
## ASV0196     -7.177327e-04 -7.503994e-04 -7.844827e-04 -8.200377e-04
## ASV12801    -2.208233e-04 -2.311621e-04 -2.419749e-04 -2.532822e-04
## ASV12906    -2.208049e-04 -2.311420e-04 -2.419528e-04 -2.532581e-04
## ASV13040    -2.207865e-04 -2.311218e-04 -2.419307e-04 -2.532339e-04
## ASV1313     -2.236729e-05 -2.364784e-05 -2.500785e-05 -2.645256e-05
## ASV14008     6.227647e-05  6.532915e-05  6.853611e-05  7.190561e-05
## ASV1546      8.528393e-05  8.889202e-05  9.263179e-05  9.650615e-05
## ASV1637      4.147096e-04  4.336470e-04  4.534105e-04  4.740327e-04
## ASV17076     1.801438e-04  1.881618e-04  1.965108e-04  2.052021e-04
## ASV2061      6.173076e-04  6.450861e-04  6.740405e-04  7.042138e-04
## ASV2177      2.548361e-04  2.668672e-04  2.794605e-04  2.926415e-04
## ASV2943      3.758092e-04  3.928656e-04  4.106564e-04  4.292097e-04
## ASV3020      3.313008e-04  3.462328e-04  3.617986e-04  3.780215e-04
## ASV30254     1.634810e-05  1.680945e-05  1.726574e-05  1.771463e-05
## ASV3219      4.648487e-04  4.858376e-04  5.077215e-04  5.305337e-04
## ASV3352      4.059274e-04  4.246208e-04  4.441454e-04  4.645354e-04
## ASV3355      1.741198e-04  1.822727e-04  1.907991e-04  1.997151e-04
## ASV3377      3.153434e-04  3.298449e-04  3.449896e-04  3.608039e-04
## ASV3449      1.837120e-04  1.918242e-04  2.002654e-04  2.090465e-04
## ASV3893      2.207669e-04  2.311002e-04  2.419070e-04  2.532077e-04
## ASV4326      1.296653e-04  1.352964e-04  1.411473e-04  1.472242e-04
## ASV5016     -2.207540e-04 -2.310861e-04 -2.418914e-04 -2.531906e-04
## ASV5152      1.720597e-04  1.793921e-04  1.869977e-04  1.948829e-04
## ASV5666     -8.432208e-06 -8.991209e-06 -9.589731e-06 -1.023059e-05
## ASV5802     -2.261795e-04 -2.367484e-04 -2.478000e-04 -2.593551e-04
## ASV6070      1.571708e-04  1.641059e-04  1.713218e-04  1.788277e-04
## ASV6488      1.364209e-04  1.425861e-04  1.490147e-04  1.557165e-04
## ASV6562     -2.207239e-04 -2.310531e-04 -2.418552e-04 -2.531508e-04
## ASV6930      1.612993e-04  1.684257e-04  1.758416e-04  1.835564e-04
## ASV7243      2.919784e-04  3.050942e-04  3.187629e-04  3.330045e-04
## ASV7506      1.856105e-04  1.938675e-04  2.024652e-04  2.114150e-04
## ASV7553     -2.207104e-04 -2.310381e-04 -2.418388e-04 -2.531328e-04
## ASV8064      1.261068e-04  1.317239e-04  1.375731e-04  1.436621e-04
## ASV8434     -1.226425e-04 -1.284958e-04 -1.346271e-04 -1.410492e-04
## ASV8858     -2.206880e-04 -2.310137e-04 -2.418119e-04 -2.531033e-04
## ASV2600      1.270046e-04  1.329457e-04  1.391582e-04  1.456541e-04
## ASV3398      4.780038e-04  5.000234e-04  5.230228e-04  5.470422e-04
## ASV4584     -2.206612e-04 -2.309842e-04 -2.417797e-04 -2.530680e-04
## ASV4864      2.418836e-04  2.529130e-04  2.644226e-04  2.764314e-04
## ASV0082     -9.445543e-04 -9.877160e-04 -1.032766e-03 -1.079778e-03
## ASV9626      1.950834e-04  2.040427e-04  2.133975e-04  2.231638e-04
## ASV1617      8.539668e-05  8.893879e-05  9.260362e-05  9.639326e-05
## ASV2765     -5.036788e-05 -5.288469e-05 -5.553058e-05 -5.831229e-05
## ASV2167     -2.933610e-04 -3.067453e-04 -3.207130e-04 -3.352868e-04
## ASV1628      1.859770e-04  1.939266e-04  2.021755e-04  2.107315e-04
## ASV3260     -4.653397e-05 -4.851586e-05 -5.057099e-05 -5.270102e-05
## ASV3645      2.720005e-05  2.865510e-05  3.019124e-05  3.181299e-05
## ASV6057     -2.799384e-04 -2.927157e-04 -3.060505e-04 -3.199647e-04
## ASV0662     -3.740247e-05 -3.898455e-05 -4.062439e-05 -4.232327e-05
## ASV4267     -3.577000e-05 -3.749990e-05 -3.931347e-05 -4.121467e-05
## ASV1070      2.990308e-04  3.130316e-04  3.276765e-04  3.429939e-04
## ASV0633     -7.749089e-05 -8.090229e-05 -8.445113e-05 -8.814179e-05
## ASV0333      3.069312e-04  3.211005e-04  3.359034e-04  3.513664e-04
## ASV0966      2.333534e-04  2.440946e-04  2.553121e-04  2.670253e-04
## ASV1848      3.363690e-04  3.521766e-04  3.687163e-04  3.860210e-04
## ASV13390    -2.143685e-04 -2.241172e-04 -2.342877e-04 -2.448964e-04
## ASV14901    -2.143511e-04 -2.240982e-04 -2.342670e-04 -2.448737e-04
## ASV1676     -2.465153e-04 -2.574635e-04 -2.688614e-04 -2.807244e-04
## ASV1756     -2.587506e-05 -2.704013e-05 -2.825439e-05 -2.951963e-05
## ASV22537    -2.968866e-05 -3.095443e-05 -3.226734e-05 -3.362854e-05
## ASV3303     -3.516106e-06 -3.757195e-06 -4.015676e-06 -4.292789e-06
## ASV4030     -8.954173e-05 -9.354110e-05 -9.770680e-05 -1.020446e-04
## ASV4871      1.713502e-04  1.792864e-04  1.875798e-04  1.962455e-04
## ASV5536      1.060136e-05  1.108632e-05  1.159281e-05  1.212175e-05
## ASV5700      7.672643e-05  8.023301e-05  8.389262e-05  8.771124e-05
## ASV8957      1.422932e-04  1.482581e-04  1.544359e-04  1.608309e-04
## ASV11210     1.369337e-04  1.435631e-04  1.505173e-04  1.578125e-04
## ASV7585     -2.143445e-04 -2.240910e-04 -2.342591e-04 -2.448651e-04
## ASV8596     -2.143272e-04 -2.240720e-04 -2.342383e-04 -2.448425e-04
## ASV9532     -8.607876e-05 -8.989607e-05 -9.386952e-05 -9.800432e-05
## ASV4254      1.551744e-04  1.623788e-04  1.699087e-04  1.777779e-04
## ASV13299    -2.143118e-04 -2.240552e-04 -2.342200e-04 -2.448225e-04
## ASV15627    -2.142944e-04 -2.240362e-04 -2.341993e-04 -2.447998e-04
## ASV6302     -1.706384e-04 -1.777654e-04 -1.851469e-04 -1.927885e-04
## ASV3040      8.621529e-05  9.017534e-05  9.431027e-05  9.862717e-05
## ASV0632      1.755613e-04  1.836617e-04  1.921239e-04  2.009632e-04
## ASV3694      2.792384e-04  2.920105e-04  3.053421e-04  3.192553e-04
## ASV1592     -5.228777e-05 -5.440599e-05 -5.659293e-05 -5.884927e-05
## ASV0538      1.423214e-04  1.490137e-04  1.560172e-04  1.633461e-04
## ASV0832      3.119256e-04  3.261488e-04  3.409915e-04  3.564780e-04
## ASV0727      2.355983e-04  2.466585e-04  2.582302e-04  2.703361e-04
## ASV1165     -3.027012e-04 -3.166384e-04 -3.311952e-04 -3.463970e-04
## ASV1325      3.365340e-05  3.579442e-05  3.808560e-05  4.053821e-05
## ASV0819      5.432013e-04  5.681795e-04  5.942654e-04  6.215042e-04
## ASV2251      2.911663e-04  3.035616e-04  3.164168e-04  3.297431e-04
## ASV0100     -1.865057e-05 -1.947259e-05 -2.032754e-05 -2.121641e-05
## ASV0444     -1.448180e-04 -1.514833e-04 -1.584456e-04 -1.657177e-04
## ASV0800      7.097577e-04  7.415013e-04  7.745721e-04  8.090174e-04
## ASV2432      1.619345e-05  1.668948e-05  1.718641e-05  1.768260e-05
## ASV2883      1.985932e-05  2.060627e-05  2.137094e-05  2.215263e-05
## ASV3894      2.261309e-05  2.336691e-05  2.412791e-05  2.489401e-05
## ASV2367      4.964026e-04  5.190101e-04  5.425997e-04  5.672097e-04
## ASV3724     -2.951776e-04 -3.085208e-04 -3.224343e-04 -3.369394e-04
## ASV2112     -2.519363e-04 -2.635332e-04 -2.756444e-04 -2.882910e-04
## ASV3661      8.719495e-05  9.129367e-05  9.558247e-05  1.000699e-04
## ASV2096     -1.823951e-04 -1.910131e-04 -2.000323e-04 -2.094705e-04
## ASV3551     -2.112460e-04 -2.206668e-04 -2.304773e-04 -2.406909e-04
## ASV11343    -7.144555e-06 -7.579348e-06 -8.043385e-06 -8.538796e-06
## ASV2051      1.810439e-04  1.894480e-04  1.982335e-04  2.074170e-04
## ASV2617     -2.486843e-04 -2.600098e-04 -2.718270e-04 -2.841550e-04
## ASV0125     -1.100759e-04 -1.151468e-04 -1.204425e-04 -1.259723e-04
## ASV0372      3.790115e-04  3.962731e-04  4.142842e-04  4.330740e-04
## ASV6751     -2.832249e-04 -2.959877e-04 -3.092924e-04 -3.231592e-04
## ASV10810     6.341061e-05  6.632343e-05  6.936580e-05  7.254317e-05
## ASV0461     -1.616860e-04 -1.692096e-04 -1.770747e-04 -1.852961e-04
## ASV1945     -9.589435e-05 -1.004230e-04 -1.051633e-04 -1.101250e-04
## ASV0882     -8.199896e-05 -8.614468e-05 -9.050815e-05 -9.510130e-05
## ASV4040     -4.121012e-05 -4.309774e-05 -4.506726e-05 -4.712170e-05
## ASV0109     -2.811642e-06 -2.912568e-06 -3.015152e-06 -3.119180e-06
## ASV0174      1.273266e-04  1.326869e-04  1.382391e-04  1.439869e-04
## ASV2851      2.179159e-04  2.274577e-04  2.373784e-04  2.476893e-04
## ASV5312      3.685147e-05  3.851870e-05  4.025912e-05  4.207591e-05
## ASV9402     -3.035879e-04 -3.173279e-04 -3.316563e-04 -3.465955e-04
## ASV4870     -2.452698e-04 -2.563002e-04 -2.677969e-04 -2.797770e-04
## ASV0589      2.931800e-04  3.065751e-04  3.205558e-04  3.351454e-04
## ASV1221      6.849615e-07  7.461240e-07  8.124809e-07  8.844373e-07
## ASV6028     -2.836794e-04 -2.966007e-04 -3.100838e-04 -3.241506e-04
## ASV5106     -1.067563e-04 -1.114789e-04 -1.163939e-04 -1.215076e-04
## ASV4977     -3.849248e-05 -4.061403e-05 -4.286095e-05 -4.524107e-05
## ASV5715     -1.863759e-04 -1.948789e-04 -2.037527e-04 -2.130119e-04
## ASV4182      7.035262e-05  7.384942e-05  7.752589e-05  8.139173e-05
## ASV2383     -1.540181e-05 -1.643382e-05 -1.754215e-05 -1.873280e-05
## ASV3985      3.347550e-04  3.503717e-04  3.667015e-04  3.837753e-04
## ASV2787     -2.515044e-04 -2.626543e-04 -2.742618e-04 -2.863424e-04
## ASV6756     -2.164802e-04 -2.264829e-04 -2.369326e-04 -2.478479e-04
## ASV1634     -3.463818e-04 -3.619130e-04 -3.780963e-04 -3.949552e-04
## ASV0649     -1.060782e-04 -1.109645e-04 -1.160675e-04 -1.213960e-04
## ASV1591     -6.622112e-06 -7.221900e-06 -7.873878e-06 -8.582301e-06
## ASV1854      3.596279e-04  3.764589e-04  3.940627e-04  4.124731e-04
## ASV4205      2.398101e-04  2.510345e-04  2.627746e-04  2.750530e-04
## ASV3293     -1.385431e-04 -1.447434e-04 -1.512031e-04 -1.579314e-04
## ASV1631      1.629145e-04  1.703748e-04  1.781634e-04  1.862938e-04
## ASV1747     -9.267427e-05 -9.712972e-05 -1.018004e-04 -1.066966e-04
## ASV5634      7.380603e-05  7.717347e-05  8.068819e-05  8.435612e-05
## ASV0965     -1.162031e-04 -1.214583e-04 -1.269387e-04 -1.326528e-04
## ASV1094      2.005242e-04  2.096002e-04  2.190657e-04  2.289355e-04
## ASV2744     -6.746395e-06 -7.357082e-06 -8.020859e-06 -8.742048e-06
## ASV7212     -3.039200e-04 -3.180473e-04 -3.328133e-04 -3.482449e-04
## ASV0344     -2.013527e-04 -2.105696e-04 -2.201912e-04 -2.302337e-04
## ASV11812    -2.180619e-04 -2.281494e-04 -2.386888e-04 -2.496990e-04
## ASV7867     -3.164203e-05 -3.319395e-05 -3.482297e-05 -3.653291e-05
## ASV6670      1.979261e-04  2.065919e-04  2.156036e-04  2.249723e-04
## ASV10991     3.636133e-06  3.348887e-06  3.008503e-06  2.609351e-06
## ASV1281      3.897812e-04  4.081566e-04  4.273879e-04  4.475139e-04
## ASV12845    -2.180464e-04 -2.281324e-04 -2.386702e-04 -2.496785e-04
## ASV1833     -2.180285e-04 -2.281128e-04 -2.386487e-04 -2.496550e-04
## ASV2211      1.416269e-04  1.478152e-04  1.542487e-04  1.609350e-04
## ASV3920      3.069843e-04  3.207252e-04  3.350403e-04  3.499499e-04
## ASV4545     -2.477275e-04 -2.592053e-04 -2.711990e-04 -2.837303e-04
## ASV4710     -2.704857e-04 -2.829867e-04 -2.960468e-04 -3.096892e-04
## ASV4978      4.309424e-05  4.510291e-05  4.720315e-05  4.939893e-05
## ASV9630     -7.583905e-06 -7.958315e-06 -8.351523e-06 -8.764475e-06
## ASV9797     -7.728571e-06 -8.359181e-06 -9.042506e-06 -9.782869e-06
## ASV13469    -2.179805e-04 -2.280602e-04 -2.385911e-04 -2.495918e-04
## ASV14961    -7.955266e-05 -8.322061e-05 -8.705163e-05 -9.105238e-05
## ASV6259      1.223613e-04  1.277823e-04  1.334246e-04  1.392957e-04
## ASV6294     -1.552065e-04 -1.623887e-04 -1.698928e-04 -1.777321e-04
## ASV6883     -7.276309e-05 -7.623158e-05 -7.986450e-05 -8.366948e-05
## ASV7041     -1.801818e-04 -1.886776e-04 -1.975682e-04 -2.068712e-04
## ASV4363     -2.112092e-04 -2.206702e-04 -2.305278e-04 -2.407963e-04
## ASV1784     -3.079506e-04 -3.220316e-04 -3.367295e-04 -3.520687e-04
## ASV2140      2.743622e-05  2.874110e-05  3.010698e-05  3.153651e-05
## ASV3202      2.111818e-04  2.206403e-04  2.304951e-04  2.407607e-04
## ASV6017     -2.111650e-04 -2.206219e-04 -2.304751e-04 -2.407388e-04
## ASV9129      1.061521e-04  1.108255e-04  1.156867e-04  1.207416e-04
## ASV0917      2.166079e-04  2.263226e-04  2.364458e-04  2.469922e-04
## ASV10584    -2.998924e-06 -2.890014e-06 -2.754740e-06 -2.590234e-06
## ASV11218     1.373710e-04  1.434388e-04  1.497524e-04  1.563198e-04
## ASV11229     2.015075e-05  2.131494e-05  2.255136e-05  2.386468e-05
## ASV11604    -2.427651e-05 -2.550009e-05 -2.678748e-05 -2.814210e-05
## ASV2103     -2.480425e-04 -2.592617e-04 -2.709615e-04 -2.831603e-04
## ASV2165     -2.111176e-04 -2.205702e-04 -2.304187e-04 -2.406773e-04
## ASV2340      2.342780e-04  2.444580e-04  2.550359e-04  2.660234e-04
## ASV3738     -2.110979e-04 -2.205487e-04 -2.303953e-04 -2.406518e-04
## ASV4012      6.407923e-05  6.694370e-05  6.992736e-05  7.303436e-05
## ASV4094     -2.110839e-04 -2.205334e-04 -2.303785e-04 -2.406335e-04
## ASV4454     -2.110670e-04 -2.205150e-04 -2.303585e-04 -2.406116e-04
## ASV7031      5.002966e-05  5.246030e-05  5.501042e-05  5.768593e-05
## ASV7087     -8.056285e-05 -8.399756e-05 -8.756067e-05 -9.125541e-05
## ASV4159      1.239085e-05  1.290041e-05  1.342688e-05  1.397044e-05
## ASV5084     -2.110481e-04 -2.204944e-04 -2.303360e-04 -2.405871e-04
## ASV6584     -2.110313e-04 -2.204760e-04 -2.303160e-04 -2.405653e-04
## ASV9614     -2.110144e-04 -2.204577e-04 -2.302960e-04 -2.405434e-04
## ASV16068    -2.109976e-04 -2.204393e-04 -2.302759e-04 -2.405216e-04
## ASV2141     -2.803886e-04 -2.925381e-04 -3.051622e-04 -3.182753e-04
## ASV0395     -1.990368e-05 -2.087250e-05 -2.188949e-05 -2.295713e-05
## ASV5640     -4.927217e-05 -5.164747e-05 -5.413746e-05 -5.674757e-05
## ASV2854     -2.372572e-04 -2.478020e-04 -2.587818e-04 -2.702115e-04
## ASV3825     -4.183630e-04 -4.374008e-04 -4.572645e-04 -4.779863e-04
## ASV0481      4.556109e-04  4.758083e-04  4.968350e-04  5.187194e-04
## ASV3304      2.130589e-05  2.231625e-05  2.337444e-05  2.448274e-05
## ASV0445      2.774170e-04  2.899395e-04  3.029956e-04  3.166052e-04
## ASV1845     -1.459088e-04 -1.527397e-04 -1.598840e-04 -1.673554e-04
## ASV3110     -1.607408e-04 -1.679960e-04 -1.755625e-04 -1.834522e-04
##                                                                    
## (Intercept) -4.233900e-06 -4.916363e-06 -5.706143e-06 -6.619401e-06
## ASV1236      2.599698e-04  2.714880e-04  2.834758e-04  2.959488e-04
## ASV0421     -4.555862e-04 -4.756031e-04 -4.964248e-04 -5.180772e-04
## ASV0691     -3.905978e-04 -4.071273e-04 -4.242658e-04 -4.420281e-04
## ASV0899      1.269440e-06  1.866026e-06  2.533200e-06  3.277139e-06
## ASV1004      5.185855e-04  5.414099e-04  5.651540e-04  5.898476e-04
## ASV1041     -3.548459e-04 -3.706534e-04 -3.871144e-04 -4.042514e-04
## ASV1058      4.833417e-04  5.046924e-04  5.269121e-04  5.500298e-04
## ASV12542     1.453804e-04  1.515020e-04  1.578467e-04  1.644196e-04
## ASV1294      5.655086e-04  5.908067e-04  6.171622e-04  6.446128e-04
## ASV13113     1.999424e-04  2.090565e-04  2.185679e-04  2.284924e-04
## ASV1318      4.942390e-04  5.162679e-04  5.392091e-04  5.630942e-04
## ASV2269     -1.506629e-04 -1.575263e-04 -1.646848e-04 -1.721494e-04
## ASV2542      3.221639e-04  3.371697e-04  3.528572e-04  3.692559e-04
## ASV2660     -2.853490e-04 -2.979580e-04 -3.110778e-04 -3.247250e-04
## ASV2737     -2.043277e-05 -2.169288e-05 -2.303373e-05 -2.446031e-05
## ASV2840      3.691833e-04  3.849673e-04  4.013458e-04  4.183340e-04
## ASV3053      1.831506e-05  1.900617e-05  1.971741e-05  2.044906e-05
## ASV3077      1.165741e-04  1.216791e-04  1.269899e-04  1.325137e-04
## ASV3134      4.103789e-04  4.293829e-04  4.492433e-04  4.699966e-04
## ASV3140      1.843684e-04  1.929867e-04  2.019954e-04  2.114106e-04
## ASV3579      7.204083e-05  7.556974e-05  7.927673e-05  8.317122e-05
## ASV6119     -1.506322e-04 -1.574928e-04 -1.646481e-04 -1.721093e-04
## ASV7557     -1.506175e-04 -1.574767e-04 -1.646305e-04 -1.720900e-04
## ASV8422      7.493782e-05  7.789895e-05  8.095176e-05  8.409704e-05
## ASV1086     -3.903780e-05 -4.065832e-05 -4.233795e-05 -4.407834e-05
## ASV1310      2.772197e-04  2.895308e-04  3.023491e-04  3.156919e-04
## ASV15750    -7.324321e-05 -7.661265e-05 -8.012824e-05 -8.379528e-05
## ASV16905    -1.506096e-04 -1.574679e-04 -1.646209e-04 -1.720794e-04
## ASV2033      2.710445e-04  2.832715e-04  2.960196e-04  3.093085e-04
## ASV2089      1.039860e-04  1.087656e-04  1.137535e-04  1.189576e-04
## ASV2127      3.952202e-04  4.125138e-04  4.304951e-04  4.491853e-04
## ASV2725      4.484086e-04  4.678611e-04  4.880742e-04  5.090704e-04
## ASV2804     -1.506042e-04 -1.574620e-04 -1.646144e-04 -1.720722e-04
## ASV3075      2.834908e-04  2.959833e-04  3.089833e-04  3.225077e-04
## ASV3327      2.677099e-04  2.798712e-04  2.925595e-04  3.057953e-04
## ASV3342      2.981203e-04  3.118201e-04  3.261237e-04  3.410552e-04
## ASV3532     -2.672734e-04 -2.794499e-04 -2.921526e-04 -3.054016e-04
## ASV3600      3.325838e-04  3.474647e-04  3.629701e-04  3.791225e-04
## ASV4013      2.784254e-04  2.906576e-04  3.033815e-04  3.166130e-04
## ASV4136      2.809241e-04  2.933378e-04  3.062558e-04  3.196948e-04
## ASV4195      1.505815e-04  1.574371e-04  1.645872e-04  1.720425e-04
## ASV4407     -1.505668e-04 -1.574210e-04 -1.645696e-04 -1.720232e-04
## ASV4717      1.533400e-06  1.211703e-06  8.446941e-07  4.283361e-07
## ASV6794      1.441315e-04  1.500671e-04  1.562084e-04  1.625596e-04
## ASV8324     -1.505604e-04 -1.574139e-04 -1.645616e-04 -1.720144e-04
## ASV8981     -4.319437e-05 -4.512716e-05 -4.713807e-05 -4.922935e-05
## ASV9859      1.120831e-04  1.173979e-04  1.229647e-04  1.287956e-04
## ASV0936     -2.272722e-04 -2.372936e-04 -2.477228e-04 -2.585738e-04
## ASV12683    -2.820900e-05 -2.973886e-05 -3.135406e-05 -3.305923e-05
## ASV1293      3.371226e-04  3.519047e-04  3.672756e-04  3.832533e-04
## ASV13055    -3.931751e-05 -4.115189e-05 -4.306668e-05 -4.506471e-05
## ASV17063    -1.505335e-04 -1.573846e-04 -1.645297e-04 -1.719796e-04
## ASV2228      1.505188e-04  1.573685e-04  1.645121e-04  1.719604e-04
## ASV2769     -3.144116e-05 -3.288503e-05 -3.439049e-05 -3.595962e-05
## ASV2803      6.233483e-05  6.467921e-05  6.708489e-05  6.955118e-05
## ASV2896      1.804983e-04  1.885063e-04  1.968465e-04  2.055310e-04
## ASV3062      5.464953e-05  5.725348e-05  5.998234e-05  6.284217e-05
## ASV3107      2.197987e-04  2.296501e-04  2.399167e-04  2.506140e-04
## ASV3265      4.360813e-04  4.551016e-04  4.748727e-04  4.954173e-04
## ASV3666     -1.294981e-05 -1.366893e-05 -1.442843e-05 -1.523041e-05
## ASV4497      1.026064e-04  1.070860e-04  1.117457e-04  1.165914e-04
## ASV6914     -5.727926e-05 -6.012929e-05 -6.312154e-05 -6.626277e-05
## ASV0576     -5.116522e-04 -5.335407e-04 -5.562576e-04 -5.798251e-04
## ASV0673      1.399781e-04  1.467041e-04  1.537523e-04  1.611377e-04
## ASV0772      1.524196e-04  1.590193e-04  1.658779e-04  1.730036e-04
## ASV0862     -1.238090e-04 -1.289999e-04 -1.343783e-04 -1.399486e-04
## ASV0898      1.336611e-04  1.400277e-04  1.466941e-04  1.536736e-04
## ASV0910      2.880248e-04  3.015913e-04  3.157882e-04  3.306438e-04
## ASV0964     -1.862125e-04 -1.942844e-04 -2.026726e-04 -2.113867e-04
## ASV10059     1.318945e-04  1.380397e-04  1.444673e-04  1.511902e-04
## ASV10263    -1.505883e-04 -1.574442e-04 -1.645944e-04 -1.720498e-04
## ASV1088      1.515924e-04  1.586870e-04  1.661081e-04  1.738701e-04
## ASV1101      2.540419e-04  2.654083e-04  2.772502e-04  2.895847e-04
## ASV1183      1.687225e-04  1.765957e-04  1.848252e-04  1.934259e-04
## ASV11956     5.642655e-05  5.849059e-05  6.060267e-05  6.276150e-05
## ASV12774    -2.844606e-05 -3.005092e-05 -3.175005e-05 -3.354888e-05
## ASV1321      6.466310e-05  6.784808e-05  7.119330e-05  7.470694e-05
## ASV13793    -1.505684e-04 -1.574222e-04 -1.645703e-04 -1.720233e-04
## ASV14482    -1.853604e-05 -1.965295e-05 -2.083916e-05 -2.209873e-05
## ASV15483     9.801069e-05  1.022500e-04  1.066559e-04  1.112337e-04
## ASV2062      6.492759e-04  6.784702e-04  7.088990e-04  7.406074e-04
## ASV2132      2.905900e-04  3.036405e-04  3.172435e-04  3.314193e-04
## ASV2413      4.146842e-04  4.329207e-04  4.518942e-04  4.716290e-04
## ASV2490      2.739596e-04  2.859153e-04  2.983442e-04  3.112610e-04
## ASV2594      1.473156e-04  1.537753e-04  1.604973e-04  1.674907e-04
## ASV2822     -1.505879e-04 -1.574435e-04 -1.645934e-04 -1.720484e-04
## ASV2863      2.575621e-04  2.690066e-04  2.809209e-04  2.933209e-04
## ASV2910      3.255099e-04  3.395113e-04  3.540497e-04  3.691401e-04
## ASV2980      1.248064e-04  1.304822e-04  1.364006e-04  1.425704e-04
## ASV3307      1.505619e-04  1.574149e-04  1.645621e-04  1.720142e-04
## ASV3474      2.314920e-04  2.422898e-04  2.535818e-04  2.653897e-04
## ASV3502      4.738694e-04  4.949670e-04  5.169390e-04  5.398158e-04
## ASV4236      2.385638e-04  2.488753e-04  2.595871e-04  2.707107e-04
## ASV4842     -8.470206e-05 -8.869028e-05 -9.285980e-05 -9.721798e-05
## ASV4894     -1.505762e-04 -1.574306e-04 -1.645792e-04 -1.720327e-04
## ASV5290      1.787441e-04  1.867156e-04  1.950199e-04  2.036688e-04
## ASV5501      3.189740e-05  3.326085e-05  3.467867e-05  3.615294e-05
## ASV5795      1.188186e-04  1.241489e-04  1.297056e-04  1.354974e-04
## ASV5987     -1.505803e-04 -1.574350e-04 -1.645840e-04 -1.720380e-04
## ASV6267     -1.505656e-04 -1.574189e-04 -1.645664e-04 -1.720188e-04
## ASV6862      2.766384e-04  2.884142e-04  3.006309e-04  3.133000e-04
## ASV7145      4.689147e-05  4.867955e-05  5.051797e-05  5.240676e-05
## ASV7673     -1.505602e-04 -1.574129e-04 -1.645597e-04 -1.720114e-04
## ASV7789      5.055811e-05  5.295007e-05  5.545584e-05  5.808092e-05
## ASV7809     -2.214155e-05 -2.315552e-05 -2.421138e-05 -2.531025e-05
## ASV8002     -1.505478e-04 -1.573995e-04 -1.645451e-04 -1.719954e-04
## ASV8205      7.755883e-05  8.071025e-05  8.396744e-05  8.733217e-05
## ASV9155     -1.142914e-04 -1.195083e-04 -1.249495e-04 -1.306232e-04
## ASV9221     -2.481654e-05 -2.612243e-05 -2.749821e-05 -2.894745e-05
## ASV9311     -1.505251e-04 -1.573746e-04 -1.645178e-04 -1.719655e-04
## ASV9557     -1.505104e-04 -1.573585e-04 -1.645002e-04 -1.719463e-04
## ASV9936     -1.504957e-04 -1.573424e-04 -1.644826e-04 -1.719271e-04
## ASV1445      3.386281e-04  3.540035e-04  3.700434e-04  3.867733e-04
## ASV4232      2.833835e-04  2.963036e-04  3.097894e-04  3.238638e-04
## ASV6479     -2.050248e-06 -1.879856e-06 -1.675214e-06 -1.432243e-06
## ASV0142     -7.328006e-04 -7.646692e-04 -7.977904e-04 -8.322019e-04
## ASV0378     -2.406657e-04 -2.510328e-04 -2.617978e-04 -2.729717e-04
## ASV1122      4.455861e-04  4.657474e-04  4.867738e-04  5.086982e-04
## ASV0123     -7.183192e-04 -7.495597e-04 -7.820282e-04 -8.157617e-04
## ASV2064      7.053810e-05  7.335681e-05  7.626780e-05  7.927266e-05
## ASV4459     -8.527991e-05 -8.924701e-05 -9.339080e-05 -9.771824e-05
## ASV0448      1.370033e-04  1.439381e-04  1.512327e-04  1.589060e-04
## ASV0397      3.376831e-04  3.530399e-04  3.690588e-04  3.857649e-04
## ASV0485      4.674036e-04  4.882560e-04  5.099740e-04  5.325877e-04
## ASV1566      3.858729e-04  4.030071e-04  4.208476e-04  4.394188e-04
## ASV1365      2.482248e-04  2.591912e-04  2.706050e-04  2.824814e-04
## ASV1065      5.189407e-04  5.422817e-04  5.666081e-04  5.919555e-04
## ASV0722     -7.612510e-06 -7.772032e-06 -7.924889e-06 -8.070018e-06
## ASV12660    -2.481977e-04 -2.592320e-04 -2.707190e-04 -2.826738e-04
## ASV0223     -2.369348e-06 -2.124156e-06 -1.838304e-06 -1.507749e-06
## ASV0229      2.353869e-04  2.462294e-04  2.575519e-04  2.693737e-04
## ASV0877     -9.201825e-05 -9.608268e-05 -1.003107e-04 -1.047075e-04
## ASV0983      4.769254e-04  4.981037e-04  5.201515e-04  5.430980e-04
## ASV0626     -1.534918e-04 -1.597666e-04 -1.662506e-04 -1.729466e-04
## ASV4146     -3.011944e-05 -3.158524e-05 -3.312051e-05 -3.472817e-05
## ASV4175     -2.947300e-04 -3.080559e-04 -3.219488e-04 -3.364297e-04
## ASV2082     -1.677275e-05 -1.753166e-05 -1.832594e-05 -1.915753e-05
## ASV2272      2.096453e-04  2.191236e-04  2.290098e-04  2.393199e-04
## ASV2245     -2.557497e-04 -2.673227e-04 -2.793887e-04 -2.919658e-04
## ASV0590     -1.512909e-04 -1.582678e-04 -1.655566e-04 -1.731705e-04
## ASV0217     -2.250464e-04 -2.337466e-04 -2.426881e-04 -2.518686e-04
## ASV0416      2.378906e-04  2.481129e-04  2.587234e-04  2.697321e-04
## ASV1056      2.847715e-04  2.980357e-04  3.119023e-04  3.263969e-04
## ASV7777     -2.582771e-04 -2.701467e-04 -2.825389e-04 -2.954745e-04
## ASV0455      5.414463e-05  5.681962e-05  5.962669e-05  6.257203e-05
## ASV0604      6.026647e-05  6.351845e-05  6.695696e-05  7.059318e-05
## ASV6100     -2.404542e-04 -2.516184e-04 -2.632847e-04 -2.754740e-04
## ASV11359    -2.625691e-04 -2.743709e-04 -2.866684e-04 -2.994790e-04
## ASV6604      1.875649e-04  1.962610e-04  2.053511e-04  2.148523e-04
## ASV5004     -1.573945e-04 -1.646006e-04 -1.721201e-04 -1.799651e-04
## ASV1483     -1.435753e-04 -1.501049e-04 -1.569149e-04 -1.640156e-04
## ASV9773     -3.053033e-04 -3.193350e-04 -3.339853e-04 -3.492787e-04
## ASV4059      3.139831e-05  3.315323e-05  3.501606e-05  3.699414e-05
## ASV1193      4.885211e-04  5.106037e-04  5.336327e-04  5.576444e-04
## ASV4610     -4.425184e-05 -4.593495e-05 -4.766016e-05 -4.942628e-05
## ASV0742     -1.819351e-04 -1.895952e-04 -1.975321e-04 -2.057519e-04
## ASV1502     -3.537446e-06 -3.859649e-06 -4.207409e-06 -4.582373e-06
## ASV0195     -5.331887e-05 -5.593031e-05 -5.867223e-05 -6.155122e-05
## ASV1213      1.576561e-04  1.646357e-04  1.718990e-04  1.794552e-04
## ASV1648     -2.267755e-04 -2.372084e-04 -2.481020e-04 -2.594750e-04
## ASV6984     -1.678255e-04 -1.754856e-04 -1.834773e-04 -1.918131e-04
## ASV0396     -1.147865e-04 -1.188171e-04 -1.229202e-04 -1.270901e-04
## ASV4297      2.464330e-04  2.570976e-04  2.681777e-04  2.796859e-04
## ASV2622      5.648756e-04  5.896626e-04  6.154442e-04  6.422524e-04
## ASV3512      8.563357e-05  8.972093e-05  9.400532e-05  9.849647e-05
## ASV2411      1.980075e-04  2.072444e-04  2.169015e-04  2.269967e-04
## ASV2291     -4.459700e-05 -4.657905e-05 -4.864499e-05 -5.079817e-05
## ASV0807      2.383525e-04  2.499571e-04  2.621302e-04  2.748994e-04
## ASV1292      1.338477e-04  1.400030e-04  1.464301e-04  1.531401e-04
## ASV1035      5.940395e-05  6.186805e-05  6.441637e-05  6.705010e-05
## ASV0070     -1.344996e-04 -1.401350e-04 -1.459729e-04 -1.520179e-04
## ASV0255      5.210840e-05  5.428562e-05  5.653706e-05  5.886350e-05
## ASV0057     -5.797521e-04 -6.046902e-04 -6.305817e-04 -6.574528e-04
## ASV0077     -8.514269e-05 -8.859965e-05 -9.217191e-05 -9.586129e-05
## ASV0625      5.857385e-04  6.115690e-04  6.384456e-04  6.664026e-04
## ASV2464      2.863698e-04  2.989621e-04  3.120596e-04  3.256784e-04
## ASV1315      5.005482e-04  5.231564e-04  5.467338e-04  5.713176e-04
## ASV2673      3.764067e-04  3.940142e-04  4.124282e-04  4.316840e-04
## ASV2161      1.522142e-04  1.592558e-04  1.666152e-04  1.743061e-04
## ASV0337     -2.467871e-04 -2.579322e-04 -2.695547e-04 -2.816728e-04
## ASV7680     -2.885450e-04 -3.016077e-04 -3.152280e-04 -3.294264e-04
## ASV0611      6.236275e-04  6.519745e-04  6.815494e-04  7.124001e-04
## ASV3118     -2.144510e-04 -2.242694e-04 -2.345165e-04 -2.452088e-04
## ASV1284      2.344534e-04  2.454925e-04  2.570366e-04  2.691068e-04
## ASV0889      1.686681e-04  1.760885e-04  1.838096e-04  1.918415e-04
## ASV4649     -1.833215e-04 -1.917815e-04 -2.006171e-04 -2.098436e-04
## ASV1108     -2.338461e-04 -2.448956e-04 -2.564588e-04 -2.685585e-04
## ASV0738     -2.459308e-05 -2.454601e-05 -2.439355e-05 -2.412270e-05
## ASV0473      3.648428e-05  3.818548e-05  3.996311e-05  4.182029e-05
## ASV0598     -2.577597e-04 -2.688957e-04 -2.804624e-04 -2.924722e-04
## ASV0429      4.117636e-04  4.300724e-04  4.491368e-04  4.689826e-04
## ASV1549      4.179087e-04  4.374636e-04  4.579160e-04  4.793055e-04
## ASV1203      3.090467e-04  3.227292e-04  3.369700e-04  3.517876e-04
## ASV4532      1.265705e-05  1.309381e-05  1.353964e-05  1.399436e-05
## ASV0274     -3.060479e-04 -3.190438e-04 -3.325243e-04 -3.465019e-04
## ASV0163     -4.407872e-04 -4.595857e-04 -4.790889e-04 -4.993148e-04
## ASV1298      1.803618e-04  1.880919e-04  1.961142e-04  2.044363e-04
## ASV9424     -3.866317e-04 -4.044078e-04 -4.229687e-04 -4.423461e-04
## ASV0412      5.873754e-04  6.135829e-04  6.408794e-04  6.693031e-04
## ASV0284      2.591864e-04  2.703185e-04  2.818732e-04  2.938619e-04
## ASV0620     -2.001871e-04 -2.096232e-04 -2.194947e-04 -2.298206e-04
## ASV0153     -4.087235e-04 -4.274709e-04 -4.470460e-04 -4.674826e-04
## ASV0498      4.965512e-05  5.262180e-05  5.577584e-05  5.912904e-05
## ASV0097      2.901444e-04  3.033832e-04  3.171996e-04  3.316164e-04
## ASV0104     -1.346676e-03 -1.406917e-03 -1.469681e-03 -1.535058e-03
## ASV1282      2.391925e-04  2.501999e-04  2.616928e-04  2.736904e-04
## ASV3883     -1.329119e-04 -1.388542e-04 -1.450415e-04 -1.514819e-04
## ASV0801      1.429726e-04  1.500079e-04  1.573944e-04  1.651496e-04
## ASV1611     -5.176100e-04 -5.409564e-04 -5.652944e-04 -5.906607e-04
## ASV0227     -1.841502e-04 -1.926101e-04 -2.014432e-04 -2.106646e-04
## ASV0833      2.055528e-04  2.153366e-04  2.255820e-04  2.363102e-04
## ASV0718      4.903555e-04  5.127484e-04  5.361201e-04  5.605096e-04
## ASV1139      1.827342e-04  1.907764e-04  1.991422e-04  2.078422e-04
## ASV0766     -1.294213e-04 -1.349825e-04 -1.407540e-04 -1.467413e-04
## ASV2091      6.403898e-04  6.680962e-04  6.968802e-04  7.267734e-04
## ASV1238     -3.011519e-05 -3.065859e-05 -3.115761e-05 -3.160539e-05
## ASV9193     -7.383082e-05 -7.808091e-05 -8.258562e-05 -8.735984e-05
## ASV0290     -5.009374e-05 -5.236539e-05 -5.473346e-05 -5.720134e-05
## ASV0231      5.076424e-04  5.300619e-04  5.533915e-04  5.776611e-04
## ASV0185      1.040761e-04  1.103956e-04  1.171292e-04  1.243047e-04
## ASV2330      1.474956e-04  1.539618e-04  1.606874e-04  1.676806e-04
## ASV3119     -1.735659e-04 -1.820392e-04 -1.909295e-04 -2.002571e-04
## ASV2368     -2.386791e-04 -2.498476e-04 -2.615269e-04 -2.737390e-04
## ASV0122     -1.858471e-04 -1.940377e-04 -2.025633e-04 -2.114357e-04
## ASV1044      3.296795e-04  3.454320e-04  3.619366e-04  3.792288e-04
## ASV0160     -4.478390e-04 -4.668811e-04 -4.866327e-04 -5.071120e-04
## ASV0326      2.940936e-04  3.073236e-04  3.211134e-04  3.354837e-04
## ASV1388      5.141002e-04  5.370578e-04  5.609726e-04  5.858787e-04
## ASV0792      5.895348e-04  6.158985e-04  6.433636e-04  6.719690e-04
## ASV0036     -3.748288e-04 -3.921773e-04 -4.103056e-04 -4.292467e-04
## ASV2125      6.056789e-04  6.329296e-04  6.613357e-04  6.909399e-04
## ASV1075      1.164616e-04  1.219160e-04  1.276234e-04  1.335952e-04
## ASV0390      1.222308e-04  1.285312e-04  1.351725e-04  1.421742e-04
## ASV3790     -4.732294e-04 -4.941128e-04 -5.158435e-04 -5.384494e-04
## ASV1535     -4.099625e-05 -4.300971e-05 -4.512010e-05 -4.733160e-05
## ASV0263      1.040538e-04  1.089255e-04  1.140201e-04  1.193471e-04
## ASV0675      8.081427e-04  8.456989e-04  8.849521e-04  9.259742e-04
## ASV3348      7.932490e-05  8.321437e-05  8.729854e-05  9.158734e-05
## ASV0058     -7.547377e-04 -7.881890e-04 -8.230144e-04 -8.592614e-04
## ASV4142      1.854230e-04  1.934477e-04  2.017850e-04  2.104440e-04
## ASV0059     -6.502566e-04 -6.790015e-04 -7.089207e-04 -7.400540e-04
## ASV0013     -1.364953e-03 -1.425903e-03 -1.489396e-03 -1.555523e-03
## ASV0033     -4.091278e-04 -4.281391e-04 -4.480115e-04 -4.687818e-04
## ASV4354     -1.751582e-04 -1.828329e-04 -1.908136e-04 -1.991099e-04
## ASV0022     -4.319374e-04 -4.519891e-04 -4.729471e-04 -4.948500e-04
## ASV0134     -1.112862e-04 -1.168174e-04 -1.226313e-04 -1.287428e-04
## ASV0415     -8.622878e-05 -8.955506e-05 -9.297505e-05 -9.648840e-05
## ASV10103    -2.978222e-04 -3.113359e-04 -3.254307e-04 -3.401289e-04
## ASV1613      4.834340e-04  5.050247e-04  5.275168e-04  5.509426e-04
## ASV0135     -2.813572e-05 -2.894883e-05 -2.975438e-05 -3.054821e-05
## ASV0469     -5.997591e-04 -6.262946e-04 -6.539138e-04 -6.826532e-04
## ASV0471      3.887391e-04  4.066107e-04  4.252705e-04  4.447498e-04
## ASV0451     -1.048943e-04 -1.099286e-04 -1.152065e-04 -1.207399e-04
## ASV0747      1.444749e-04  1.510892e-04  1.579919e-04  1.651940e-04
## ASV1314     -2.315041e-04 -2.424958e-04 -2.540040e-04 -2.660522e-04
## ASV0425     -6.752572e-04 -7.045872e-04 -7.350679e-04 -7.667341e-04
## ASV0559     -3.794568e-04 -3.956799e-04 -4.125156e-04 -4.299802e-04
## ASV0148     -4.151776e-04 -4.330719e-04 -4.516560e-04 -4.709495e-04
## ASV0129     -2.047385e-04 -2.131944e-04 -2.219446e-04 -2.309948e-04
## ASV1072      1.992082e-04  2.076489e-04  2.164032e-04  2.254793e-04
## ASV2390      1.456997e-04  1.520308e-04  1.586098e-04  1.654440e-04
## ASV0548      4.428096e-04  4.630524e-04  4.841838e-04  5.062397e-04
## ASV0168     -6.534228e-04 -6.821086e-04 -7.119484e-04 -7.429799e-04
## ASV0066     -4.921475e-04 -5.142158e-04 -5.372133e-04 -5.611741e-04
## ASV0468     -1.898296e-04 -1.987752e-04 -2.081367e-04 -2.179328e-04
## ASV0172     -9.910610e-05 -1.028432e-04 -1.066773e-04 -1.106071e-04
## ASV0236     -2.463354e-04 -2.562414e-04 -2.664651e-04 -2.770098e-04
## ASV0250      2.109034e-05  2.326577e-05  2.563918e-05  2.822666e-05
## ASV0338     -2.397040e-05 -2.402736e-05 -2.399966e-05 -2.387717e-05
## ASV0450      1.884299e-06  2.168669e-06  2.482828e-06  2.829432e-06
## ASV0377      5.418877e-04  5.663671e-04  5.918922e-04  6.185024e-04
## ASV1022      1.548040e-04  1.620283e-04  1.695822e-04  1.774802e-04
## ASV6174     -3.313851e-05 -3.437465e-05 -3.563884e-05 -3.692979e-05
## ASV0786      6.152919e-05  6.419564e-05  6.696510e-05  6.984042e-05
## ASV0053     -6.504178e-04 -6.798147e-04 -7.104697e-04 -7.424305e-04
## ASV0697     -1.855389e-04 -1.934659e-04 -2.016930e-04 -2.102283e-04
## ASV0785      4.833170e-04  5.051369e-04  5.278924e-04  5.516195e-04
## ASV1967     -3.212167e-04 -3.353543e-04 -3.500622e-04 -3.653590e-04
## ASV0385     -1.447294e-04 -1.507901e-04 -1.570723e-04 -1.635819e-04
## ASV0295      1.904308e-06  2.490682e-06  3.146450e-06  3.878063e-06
## ASV0072     -5.134290e-04 -5.358395e-04 -5.591414e-04 -5.833628e-04
## ASV0157     -2.062177e-04 -2.146197e-04 -2.232966e-04 -2.322511e-04
## ASV0501      2.417959e-04  2.532133e-04  2.651560e-04  2.776463e-04
## ASV10729    -3.987844e-04 -4.170140e-04 -4.360399e-04 -4.558934e-04
## ASV1470      1.741702e-04  1.812701e-04  1.886091e-04  1.961910e-04
## ASV0050     -1.286901e-03 -1.344016e-03 -1.403482e-03 -1.465380e-03
## ASV0411     -3.494043e-05 -3.639818e-05 -3.791140e-05 -3.948207e-05
## ASV0549      2.489915e-04  2.606867e-04  2.729249e-04  2.857308e-04
## ASV0184      1.530539e-04  1.600118e-04  1.672709e-04  1.748432e-04
## ASV0705      1.877384e-04  1.965865e-04  2.058440e-04  2.155288e-04
## ASV1715      4.596922e-04  4.804628e-04  5.021220e-04  5.247034e-04
## ASV0603      5.982190e-05  6.283723e-05  6.601019e-05  6.934938e-05
## ASV0826      1.523731e-04  1.589587e-04  1.657992e-04  1.729020e-04
## ASV0034     -5.844027e-04 -6.102567e-04 -6.371651e-04 -6.651631e-04
## ASV0838      1.403364e-04  1.473279e-04  1.546719e-04  1.623858e-04
## ASV0614     -3.401582e-04 -3.556380e-04 -3.717896e-04 -3.886396e-04
## ASV0014     -1.248581e-03 -1.304094e-03 -1.361902e-03 -1.422084e-03
## ASV0585     -7.145607e-05 -7.438880e-05 -7.742158e-05 -8.055611e-05
## ASV0016     -1.276963e-03 -1.333790e-03 -1.392971e-03 -1.454587e-03
## ASV5394     -3.302848e-04 -3.454449e-04 -3.612730e-04 -3.777961e-04
## ASV0666      2.779536e-04  2.904173e-04  3.034042e-04  3.169328e-04
## ASV2085      1.066065e-04  1.107426e-04  1.149963e-04  1.193668e-04
## ASV0003     -1.167424e-03 -1.219245e-03 -1.273202e-03 -1.329366e-03
## ASV0346     -1.716780e-05 -1.715111e-05 -1.706457e-05 -1.689973e-05
## ASV0267     -1.895362e-04 -1.978857e-04 -2.065730e-04 -2.156092e-04
## ASV0353      2.584623e-04  2.709658e-04  2.840717e-04  2.978080e-04
## ASV2419      3.312260e-04  3.459316e-04  3.612433e-04  3.771819e-04
## ASV0447      1.614452e-04  1.695107e-04  1.779881e-04  1.868983e-04
## ASV0654      5.112155e-04  5.343629e-04  5.585021e-04  5.836705e-04
## ASV0151      8.157401e-05  8.572332e-05  9.009299e-05  9.469533e-05
## ASV0065     -4.720418e-04 -4.931159e-04 -5.150707e-04 -5.379380e-04
## ASV0527      3.466297e-04  3.623402e-04  3.787268e-04  3.958156e-04
## ASV4055     -1.383376e-04 -1.452212e-04 -1.524572e-04 -1.600643e-04
## ASV0166     -3.802986e-04 -3.963763e-04 -4.130462e-04 -4.303226e-04
## ASV0417     -3.309910e-04 -3.455842e-04 -3.607691e-04 -3.765652e-04
## ASV0078     -2.644897e-04 -2.759955e-04 -2.879558e-04 -3.003847e-04
## ASV0322     -3.150153e-04 -3.283956e-04 -3.422753e-04 -3.566674e-04
## ASV0156     -4.080504e-04 -4.254892e-04 -4.435879e-04 -4.623645e-04
## ASV0648     -3.869138e-04 -4.047593e-04 -4.233985e-04 -4.428639e-04
## ASV0407      2.068143e-05  2.138179e-05  2.209251e-05  2.281240e-05
## ASV2030     -7.891595e-05 -8.210709e-05 -8.540107e-05 -8.879884e-05
## ASV0300      2.336165e-04  2.450030e-04  2.569477e-04  2.694776e-04
## ASV1150     -3.253992e-05 -3.400585e-05 -3.553359e-05 -3.712534e-05
## ASV0958      2.388439e-04  2.502970e-04  2.623000e-04  2.748792e-04
## ASV0216     -4.034685e-04 -4.212029e-04 -4.396496e-04 -4.588314e-04
## ASV0446      5.668248e-04  5.932979e-04  6.209770e-04  6.499139e-04
## ASV0367     -1.909759e-04 -1.994862e-04 -2.083500e-04 -2.175798e-04
## ASV0200     -3.498988e-04 -3.653561e-04 -3.814469e-04 -3.981932e-04
## ASV0334     -1.727107e-04 -1.792502e-04 -1.859580e-04 -1.928311e-04
## ASV1311      2.611778e-04  2.732419e-04  2.858467e-04  2.990150e-04
## ASV0458      2.728857e-04  2.851066e-04  2.978407e-04  3.111069e-04
## ASV1371      3.571739e-06  3.536804e-06  3.482451e-06  3.406319e-06
## ASV0418      3.188499e-04  3.325930e-04  3.468662e-04  3.616848e-04
## ASV0004      3.899220e-04  4.072084e-04  4.252050e-04  4.439359e-04
## ASV1943      2.855876e-04  2.980968e-04  3.111066e-04  3.246333e-04
## ASV1495     -7.279023e-05 -7.651322e-05 -8.043389e-05 -8.456303e-05
## ASV0901     -4.542847e-04 -4.752740e-04 -4.972033e-04 -5.201119e-04
## ASV0628      2.657135e-04  2.776045e-04  2.899945e-04  3.029015e-04
## ASV0400      1.038343e-04  1.083383e-04  1.130157e-04  1.178713e-04
## ASV0116     -3.374160e-04 -3.526086e-04 -3.684465e-04 -3.849537e-04
## ASV0788      2.837693e-04  2.964948e-04  3.097557e-04  3.235714e-04
## ASV0117      1.847618e-04  1.934519e-04  2.025452e-04  2.120597e-04
## ASV3137      5.077713e-05  5.305840e-05  5.543730e-05  5.791774e-05
## ASV0001      4.749460e-04  4.958999e-04  5.177073e-04  5.403970e-04
## ASV1651      3.012920e-04  3.138406e-04  3.268315e-04  3.402733e-04
## ASV1692      3.419523e-04  3.579351e-04  3.746488e-04  3.921250e-04
## ASV0660      1.911035e-04  1.991914e-04  2.075733e-04  2.162554e-04
## ASV0508      2.533160e-05  2.638541e-05  2.747579e-05  2.860331e-05
## ASV1660     -1.381544e-04 -1.445905e-04 -1.513175e-04 -1.583473e-04
## ASV0233      7.817455e-05  8.190288e-05  8.580978e-05  8.990390e-05
## ASV1343     -3.404049e-04 -3.558759e-04 -3.720156e-04 -3.888498e-04
## ASV0209      3.197124e-04  3.339546e-04  3.487895e-04  3.642382e-04
## ASV0193     -3.945904e-04 -4.113881e-04 -4.288160e-04 -4.468908e-04
## ASV0357     -3.059327e-05 -3.191726e-05 -3.329004e-05 -3.471241e-05
## ASV0198      9.254232e-05  9.696606e-05  1.015989e-04  1.064504e-04
## ASV0007      4.512299e-04  4.711843e-04  4.919557e-04  5.135724e-04
## ASV1772     -4.425218e-05 -4.613030e-05 -4.807741e-05 -5.009505e-05
## ASV0009      4.261419e-04  4.449810e-04  4.645912e-04  4.849991e-04
## ASV0006      1.694851e-04  1.765904e-04  1.839521e-04  1.915761e-04
## ASV0011     -4.769450e-04 -4.987623e-04 -5.215347e-04 -5.453000e-04
## ASV0015      3.289050e-04  3.435602e-04  3.588239e-04  3.747175e-04
## ASV0017      3.482247e-04  3.637156e-04  3.798478e-04  3.966439e-04
## ASV0235     -2.748621e-04 -2.872338e-04 -3.001271e-04 -3.135607e-04
## ASV0382      5.620156e-05  5.950041e-05  6.300536e-05  6.672954e-05
## ASV2357      4.190176e-04  4.378678e-04  4.575157e-04  4.779905e-04
## ASV0567     -3.059014e-04 -3.195259e-04 -3.337173e-04 -3.484959e-04
## ASV0165      3.375495e-04  3.528330e-04  3.687711e-04  3.853882e-04
## ASV0005      6.655995e-04  6.948465e-04  7.252709e-04  7.569110e-04
## ASV0384     -3.515528e-05 -3.660474e-05 -3.810395e-05 -3.965374e-05
## ASV0002      1.419429e-04  1.484411e-04  1.552242e-04  1.623034e-04
## ASV3017      3.898256e-04  4.069212e-04  4.247021e-04  4.431901e-04
## ASV0091      1.507692e-04  1.576563e-04  1.648432e-04  1.723416e-04
## ASV0186     -4.007172e-04 -4.186313e-04 -4.372929e-04 -4.567284e-04
## ASV0370      4.464285e-05  4.690114e-05  4.927903e-05  5.178327e-05
## ASV0018      6.936797e-04  7.242358e-04  7.560288e-04  7.890997e-04
## ASV1377      6.099521e-04  6.369237e-04  6.649943e-04  6.942005e-04
## ASV0019      6.946782e-04  7.252889e-04  7.571399e-04  7.902720e-04
## ASV0023      4.795071e-05  4.960300e-05  5.128193e-05  5.298492e-05
## ASV2194      2.249318e-04  2.350744e-04  2.456524e-04  2.566830e-04
## ASV1155     -1.961116e-05 -1.999429e-05 -2.034935e-05 -2.067145e-05
## ASV0510     -2.470542e-04 -2.571255e-04 -2.675340e-04 -2.782847e-04
## ASV2371     -2.509283e-04 -2.617003e-04 -2.728824e-04 -2.844857e-04
## ASV0024      1.426626e-05  1.440259e-05  1.450124e-05  1.455722e-05
## ASV2452      3.287247e-04  3.431048e-04  3.580587e-04  3.736046e-04
## ASV2332      6.095954e-06  6.372481e-06  6.663135e-06  6.968904e-06
## ASV2591      1.515945e-05  1.630619e-05  1.754249e-05  1.887513e-05
## ASV0521      4.635306e-04  4.853190e-04  5.081122e-04  5.319544e-04
## ASV5542      1.384668e-04  1.448765e-04  1.515733e-04  1.585694e-04
## ASV0336     -2.004297e-04 -2.089100e-04 -2.177037e-04 -2.268184e-04
## ASV10102     3.109415e-04  3.249890e-04  3.396351e-04  3.549021e-04
## ASV16823    -2.459238e-04 -2.565525e-04 -2.675926e-04 -2.790559e-04
## ASV3104      2.459010e-04  2.565277e-04  2.675656e-04  2.790267e-04
## ASV0781      1.233589e-04  1.290681e-04  1.350339e-04  1.412672e-04
## ASV10899     1.151201e-04  1.207508e-04  1.266601e-04  1.328617e-04
## ASV11222    -2.458861e-04 -2.565116e-04 -2.675482e-04 -2.790078e-04
## ASV11327    -2.458633e-04 -2.564868e-04 -2.675213e-04 -2.789785e-04
## ASV12458    -2.458406e-04 -2.564621e-04 -2.674944e-04 -2.789493e-04
## ASV1636     -1.986610e-04 -2.071127e-04 -2.158790e-04 -2.249679e-04
## ASV1890     -2.443605e-04 -2.549733e-04 -2.660018e-04 -2.774582e-04
## ASV2898      5.318561e-04  5.555980e-04  5.803284e-04  6.060822e-04
## ASV8328     -3.869250e-05 -3.980945e-05 -4.091832e-05 -4.201404e-05
## ASV0709     -4.303785e-04 -4.494478e-04 -4.692984e-04 -4.899568e-04
## ASV0856      7.324832e-05  7.692030e-05  8.078240e-05  8.484479e-05
## ASV0909     -1.772514e-04 -1.843651e-04 -1.917043e-04 -1.992709e-04
## ASV0937     -3.375761e-04 -3.528031e-04 -3.686786e-04 -3.852269e-04
## ASV11390    -2.457925e-04 -2.564099e-04 -2.674377e-04 -2.788878e-04
## ASV11966     1.217007e-04  1.272735e-04  1.330898e-04  1.391590e-04
## ASV12990     6.883681e-05  7.208100e-05  7.547582e-05  7.902800e-05
## ASV14797     2.550576e-04  2.663267e-04  2.780548e-04  2.902570e-04
## ASV14904    -2.457862e-04 -2.564031e-04 -2.674304e-04 -2.788799e-04
## ASV15304     6.304289e-05  6.605110e-05  6.920088e-05  7.249852e-05
## ASV16696    -2.457672e-04 -2.563824e-04 -2.674080e-04 -2.788556e-04
## ASV1690      1.273162e-04  1.334042e-04  1.397811e-04  1.464600e-04
## ASV2029      6.807479e-04  7.111768e-04  7.428758e-04  7.758899e-04
## ASV2834      3.604772e-04  3.765319e-04  3.932507e-04  4.106565e-04
## ASV4003      1.087754e-04  1.143553e-04  1.202343e-04  1.264289e-04
## ASV4064      2.484746e-04  2.595238e-04  2.710286e-04  2.830045e-04
## ASV4294      9.355181e-05  9.837537e-05  1.034598e-04  1.088198e-04
## ASV4609     -1.211425e-05 -1.261562e-05 -1.313350e-05 -1.366797e-05
## ASV6283     -2.457648e-04 -2.563801e-04 -2.674057e-04 -2.788535e-04
## ASV6491     -2.457421e-04 -2.563553e-04 -2.673788e-04 -2.788243e-04
## ASV7453      1.001033e-04  1.051042e-04  1.103602e-04  1.158841e-04
## ASV7959      1.832358e-05  1.947353e-05  2.070042e-05  2.200941e-05
## ASV8219      2.457264e-04  2.563384e-04  2.673605e-04  2.788046e-04
## ASV8547     -2.457037e-04 -2.563137e-04 -2.673337e-04 -2.787754e-04
## ASV9319      1.629486e-04  1.702762e-04  1.779127e-04  1.858695e-04
## ASV9382     -2.456895e-04 -2.562983e-04 -2.673170e-04 -2.787572e-04
## ASV11516    -2.456667e-04 -2.562736e-04 -2.672901e-04 -2.787280e-04
## ASV14377    -2.456440e-04 -2.562489e-04 -2.672632e-04 -2.786989e-04
## ASV1867      3.629077e-04  3.795343e-04  3.968921e-04  4.150103e-04
## ASV1895     -8.417493e-05 -8.779950e-05 -9.156379e-05 -9.547185e-05
## ASV3168      1.514115e-04  1.580310e-04  1.649132e-04  1.720662e-04
## ASV4449      3.062638e-04  3.196810e-04  3.336344e-04  3.481412e-04
## ASV6596      1.839117e-04  1.929668e-04  2.024778e-04  2.124682e-04
## ASV7492     -9.100506e-05 -9.459738e-05 -9.829753e-05 -1.021057e-04
## ASV9854     -1.254434e-04 -1.307258e-04 -1.361998e-04 -1.418697e-04
## ASV6296      2.455967e-04  2.561975e-04  2.672076e-04  2.786386e-04
## ASV4201      8.339265e-05  8.780893e-05  9.247174e-05  9.739541e-05
## ASV0552      6.086601e-04  6.366180e-04  6.658095e-04  6.962842e-04
## ASV3671     -4.661938e-05 -4.817618e-05 -4.975019e-05 -5.133773e-05
## ASV3529     -5.512660e-05 -5.720703e-05 -5.934083e-05 -6.152707e-05
## ASV1060      1.558375e-04  1.631561e-04  1.708142e-04  1.788272e-04
## ASV0239     -3.326478e-04 -3.466357e-04 -3.611290e-04 -3.761386e-04
## ASV5711     -3.137004e-04 -3.273345e-04 -3.415034e-04 -3.562233e-04
## ASV4152     -4.127393e-04 -4.308565e-04 -4.497004e-04 -4.692941e-04
## ASV1461      3.692956e-04  3.853362e-04  4.020055e-04  4.193222e-04
## ASV2877      2.997573e-04  3.129608e-04  3.266979e-04  3.409861e-04
## ASV0012      2.260182e-04  2.363647e-04  2.471644e-04  2.584354e-04
## ASV9823      6.802383e-05  7.033065e-05  7.267364e-05  7.504947e-05
## ASV0008      2.466502e-04  2.578673e-04  2.695698e-04  2.817762e-04
## ASV7832     -2.573847e-04 -2.687524e-04 -2.805824e-04 -2.928901e-04
## ASV1915      2.121152e-05  2.240343e-05  2.366602e-05  2.500350e-05
## ASV0055      1.768086e-04  1.847341e-04  1.929921e-04  2.015945e-04
## ASV0032      4.344675e-04  4.540179e-04  4.743979e-04  4.956386e-04
## ASV2977     -3.479616e-04 -3.632452e-04 -3.791426e-04 -3.956733e-04
## ASV0466      3.492394e-04  3.642394e-04  3.798114e-04  3.959708e-04
## ASV3866      3.782417e-04  3.955422e-04  4.136007e-04  4.324472e-04
## ASV0040      4.952809e-04  5.177130e-04  5.411067e-04  5.654985e-04
## ASV0496     -3.077577e-05 -3.272526e-05 -3.480798e-05 -3.703330e-05
## ASV0052      6.025607e-04  6.292432e-04  6.570173e-04  6.859200e-04
## ASV3828     -3.772188e-04 -3.940757e-04 -4.116378e-04 -4.299305e-04
## ASV1930      2.365186e-04  2.473258e-04  2.586039e-04  2.703713e-04
## ASV2126      3.805961e-04  3.977123e-04  4.155534e-04  4.341461e-04
## ASV0793      2.232673e-04  2.335187e-04  2.442238e-04  2.554012e-04
## ASV0299     -1.555773e-04 -1.619780e-04 -1.685951e-04 -1.754319e-04
## ASV0208      3.649762e-04  3.822476e-04  4.003264e-04  4.192492e-04
## ASV0511     -1.871806e-04 -1.948383e-04 -2.027524e-04 -2.109267e-04
## ASV1123     -2.461504e-04 -2.564527e-04 -2.671232e-04 -2.781695e-04
## ASV0099     -1.320206e-04 -1.375220e-04 -1.432172e-04 -1.491099e-04
## ASV0752     -3.079659e-05 -3.248863e-05 -3.428006e-05 -3.617705e-05
## ASV0883      1.869112e-06  1.998008e-06  2.136981e-06  2.286901e-06
## ASV0683      3.232138e-04  3.383889e-04  3.542649e-04  3.708728e-04
## ASV4117     -3.712380e-04 -3.874464e-04 -4.042968e-04 -4.218088e-04
## ASV2172      1.396209e-04  1.458993e-04  1.524442e-04  1.592657e-04
## ASV0330     -2.566154e-04 -2.683156e-04 -2.805282e-04 -2.932738e-04
## ASV0728      2.282164e-04  2.381307e-04  2.484355e-04  2.591429e-04
## ASV0499      4.889446e-04  5.119295e-04  5.359779e-04  5.611369e-04
## ASV0120     -5.277973e-04 -5.514014e-04 -5.759904e-04 -6.015991e-04
## ASV1446      4.294616e-05  4.451250e-05  4.611202e-05  4.774299e-05
## ASV17171    -3.587000e-04 -3.746957e-04 -3.913560e-04 -4.087043e-04
## ASV0533      1.039178e-04  1.088461e-04  1.140051e-04  1.194052e-04
## ASV2495     -1.439394e-04 -1.504563e-04 -1.572533e-04 -1.643411e-04
## ASV5582      1.227473e-04  1.278507e-04  1.331342e-04  1.386016e-04
## ASV1488      1.300470e-04  1.366506e-04  1.435945e-04  1.508958e-04
## ASV0682      3.410528e-04  3.570942e-04  3.738772e-04  3.914343e-04
## ASV0068     -1.985500e-05 -2.104284e-05 -2.230618e-05 -2.364985e-05
## ASV1987     -1.809329e-04 -1.895117e-04 -1.984929e-04 -2.078948e-04
## ASV0035      6.111423e-05  6.328276e-05  6.548978e-05  6.773182e-05
## ASV7192     -2.367356e-04 -2.468528e-04 -2.573504e-04 -2.682383e-04
## ASV0873      3.455454e-05  3.578331e-05  3.703609e-05  3.831148e-05
## ASV4749      2.095915e-05  2.145505e-05  2.193195e-05  2.238566e-05
## ASV2174      2.151588e-04  2.238930e-04  2.329200e-04  2.422448e-04
## ASV1476     -1.957095e-04 -2.043831e-04 -2.134128e-04 -2.228108e-04
## ASV0740     -4.888445e-04 -5.114743e-04 -5.351198e-04 -5.598236e-04
## ASV0170      1.035995e-04  1.082991e-04  1.132022e-04  1.183167e-04
## ASV2466     -4.431635e-04 -4.632017e-04 -4.840989e-04 -5.058879e-04
## ASV1709      3.400495e-04  3.551372e-04  3.708457e-04  3.871964e-04
## ASV6170     -2.853991e-04 -2.971817e-04 -3.093791e-04 -3.220008e-04
## ASV3673      3.447318e-04  3.598181e-04  3.755125e-04  3.918354e-04
## ASV1745      2.038299e-05  2.104513e-05  2.171684e-05  2.239737e-05
## ASV0380     -2.269439e-04 -2.361172e-04 -2.455972e-04 -2.553894e-04
## ASV0426     -6.818015e-05 -7.075475e-05 -7.339544e-05 -7.610099e-05
## ASV0202     -6.622592e-05 -6.815538e-05 -7.007317e-05 -7.197076e-05
## ASV6350     -2.874372e-04 -2.994880e-04 -3.119817e-04 -3.249301e-04
## ASV0713     -2.075373e-04 -2.167474e-04 -2.263386e-04 -2.363245e-04
## ASV1822      4.191307e-05  4.394127e-05  4.606417e-05  4.828555e-05
## ASV4569      3.350918e-04  3.498350e-04  3.651772e-04  3.811387e-04
## ASV0030     -7.641593e-05 -8.010906e-05 -8.397928e-05 -8.803465e-05
## ASV0331      1.424084e-04  1.493718e-04  1.566810e-04  1.643534e-04
## ASV2981      3.439432e-04  3.598500e-04  3.764655e-04  3.938185e-04
## ASV0828     -2.301592e-04 -2.409693e-04 -2.522759e-04 -2.641003e-04
## ASV2440      5.445496e-04  5.697766e-04  5.961357e-04  6.236740e-04
## ASV3006     -2.304065e-04 -2.397494e-04 -2.494076e-04 -2.593871e-04
## ASV3875     -2.303866e-04 -2.397280e-04 -2.493844e-04 -2.593621e-04
## ASV4511      1.377665e-04  1.443300e-04  1.512041e-04  1.584028e-04
## ASV4700     -2.303670e-04 -2.397067e-04 -2.493615e-04 -2.593372e-04
## ASV5804     -2.303472e-04 -2.396853e-04 -2.493383e-04 -2.593122e-04
## ASV6826      2.532586e-04  2.651837e-04  2.776623e-04  2.907190e-04
## ASV7280      2.086733e-04  2.183400e-04  2.284345e-04  2.389736e-04
## ASV7535     -2.303373e-04 -2.396747e-04 -2.493270e-04 -2.593002e-04
## ASV0651     -2.419251e-04 -2.524780e-04 -2.634469e-04 -2.748441e-04
## ASV0913      3.303991e-04  3.458242e-04  3.619553e-04  3.788234e-04
## ASV10832    -2.303185e-04 -2.396544e-04 -2.493050e-04 -2.592764e-04
## ASV1117     -4.638473e-04 -4.843378e-04 -5.056663e-04 -5.278615e-04
## ASV11329     1.188435e-04  1.251779e-04  1.318647e-04  1.389239e-04
## ASV13209    -1.077028e-05 -1.045556e-05 -1.006558e-05 -9.593342e-06
## ASV1345      5.790483e-05  6.066545e-05  6.355107e-05  6.656629e-05
## ASV1719     -2.302883e-04 -2.396218e-04 -2.492700e-04 -2.592388e-04
## ASV1886      2.680298e-04  2.799512e-04  2.923710e-04  3.053076e-04
## ASV2158     -6.074219e-05 -6.275258e-05 -6.479368e-05 -6.686309e-05
## ASV2189      2.880630e-04  3.011110e-04  3.147209e-04  3.289144e-04
## ASV2257      2.110736e-04  2.203389e-04  2.299800e-04  2.400098e-04
## ASV2283      2.302442e-04  2.395740e-04  2.492183e-04  2.591827e-04
## ASV2328      2.302244e-04  2.395526e-04  2.491951e-04  2.591577e-04
## ASV2434     -3.443189e-04 -3.591938e-04 -3.746519e-04 -3.907117e-04
## ASV2648      2.301810e-04  2.395056e-04  2.491441e-04  2.591025e-04
## ASV2698      3.388063e-04  3.543233e-04  3.705246e-04  3.874385e-04
## ASV2775      3.993596e-04  4.163615e-04  4.340021e-04  4.522986e-04
## ASV3171      2.301396e-04  2.394607e-04  2.490954e-04  2.590497e-04
## ASV3227      2.941649e-04  3.065198e-04  3.193237e-04  3.325870e-04
## ASV3397      1.833585e-05  1.922638e-05  2.015544e-05  2.112389e-05
## ASV3444      3.324480e-04  3.466525e-04  3.614009e-04  3.767093e-04
## ASV3556      2.300879e-04  2.394047e-04  2.490348e-04  2.589841e-04
## ASV3606     -2.300682e-04 -2.393833e-04 -2.490117e-04 -2.589591e-04
## ASV4190      2.968856e-04  3.103139e-04  3.243192e-04  3.389238e-04
## ASV4197      3.388615e-04  3.531934e-04  3.680576e-04  3.834679e-04
## ASV4722      3.081434e-04  3.217987e-04  3.360155e-04  3.508135e-04
## ASV4765      7.904696e-05  8.283041e-05  8.678946e-05  9.093133e-05
## ASV4809      2.300191e-04  2.393301e-04  2.489540e-04  2.588967e-04
## ASV4846      2.207164e-04  2.308289e-04  2.413834e-04  2.523969e-04
## ASV4903     -5.724870e-05 -5.895465e-05 -6.066501e-05 -6.237525e-05
## ASV4944     -2.299999e-04 -2.393095e-04 -2.489319e-04 -2.588730e-04
## ASV5151     -9.071453e-05 -9.549381e-05 -1.005311e-04 -1.058398e-04
## ASV5413     -2.299856e-04 -2.392941e-04 -2.489154e-04 -2.588553e-04
## ASV5537     -2.299659e-04 -2.392728e-04 -2.488924e-04 -2.588304e-04
## ASV5688      2.299461e-04  2.392514e-04  2.488693e-04  2.588055e-04
## ASV5752      1.115331e-04  1.168005e-04  1.223068e-04  1.280614e-04
## ASV6122     -2.299316e-04 -2.392358e-04 -2.488524e-04 -2.587873e-04
## ASV6135      2.299118e-04  2.392144e-04  2.488293e-04  2.587624e-04
## ASV6188     -2.298921e-04 -2.391931e-04 -2.488063e-04 -2.587375e-04
## ASV6216      3.424734e-04  3.571425e-04  3.723746e-04  3.881863e-04
## ASV6242      2.298501e-04  2.391475e-04  2.487569e-04  2.586840e-04
## ASV6383      2.298303e-04  2.391262e-04  2.487339e-04  2.586591e-04
## ASV6781      2.298106e-04  2.391049e-04  2.487108e-04  2.586342e-04
## ASV6799     -2.297909e-04 -2.390835e-04 -2.486878e-04 -2.586093e-04
## ASV7374     -2.297712e-04 -2.390622e-04 -2.486647e-04 -2.585845e-04
## ASV7539     -2.297515e-04 -2.390409e-04 -2.486417e-04 -2.585596e-04
## ASV8591     -2.297318e-04 -2.390196e-04 -2.486187e-04 -2.585347e-04
## ASV8637      2.297120e-04  2.389983e-04  2.485956e-04  2.585098e-04
## ASV12796    -2.296923e-04 -2.389770e-04 -2.485726e-04 -2.584850e-04
## ASV1934      2.701629e-04  2.825076e-04  2.953927e-04  3.088398e-04
## ASV22549     1.800037e-05  1.963998e-05  2.141452e-05  2.333361e-05
## ASV29857    -2.296738e-04 -2.389570e-04 -2.485511e-04 -2.584619e-04
## ASV3215      3.291888e-04  3.444312e-04  3.603591e-04  3.770014e-04
## ASV3236     -2.296527e-04 -2.389342e-04 -2.485265e-04 -2.584353e-04
## ASV3954     -2.296330e-04 -2.389129e-04 -2.485035e-04 -2.584104e-04
## ASV4850      2.296133e-04  2.388916e-04  2.484805e-04  2.583856e-04
## ASV5225      2.295936e-04  2.388703e-04  2.484575e-04  2.583607e-04
## ASV5532     -2.295740e-04 -2.388490e-04 -2.484345e-04 -2.583359e-04
## ASV7258      3.264265e-05  3.524866e-05  3.805994e-05  4.109157e-05
## ASV9474     -1.297702e-04 -1.346385e-04 -1.396377e-04 -1.447676e-04
## ASV11857    -2.295482e-04 -2.388214e-04 -2.484049e-04 -2.583042e-04
## ASV1202     -2.295285e-04 -2.388001e-04 -2.483819e-04 -2.582794e-04
## ASV14742     1.682582e-04  1.765810e-04  1.853203e-04  1.944965e-04
## ASV16652     8.518832e-05  8.931680e-05  9.364018e-05  9.816660e-05
## ASV2019      3.394897e-04  3.541893e-04  3.694661e-04  3.853382e-04
## ASV2410     -3.172931e-04 -3.314733e-04 -3.462489e-04 -3.616422e-04
## ASV2718      3.408990e-04  3.568937e-04  3.736205e-04  3.911105e-04
## ASV2738      3.794561e-04  3.955116e-04  4.121619e-04  4.294221e-04
## ASV2876      2.294855e-04  2.387537e-04  2.483318e-04  2.582253e-04
## ASV3177      2.294659e-04  2.387324e-04  2.483088e-04  2.582005e-04
## ASV4367      2.294462e-04  2.387112e-04  2.482858e-04  2.581757e-04
## ASV4635      8.322170e-05  8.789505e-05  9.283980e-05  9.807119e-05
## ASV4896      2.412192e-05  2.640136e-05  2.887737e-05  3.156520e-05
## ASV4907      1.741010e-04  1.828178e-04  1.919771e-04  2.016007e-04
## ASV5230     -2.294471e-04 -2.387126e-04 -2.482880e-04 -2.581787e-04
## ASV6509     -2.294274e-04 -2.386914e-04 -2.482650e-04 -2.581539e-04
## ASV7376     -2.294077e-04 -2.386701e-04 -2.482420e-04 -2.581291e-04
## ASV8163     -2.293881e-04 -2.386489e-04 -2.482191e-04 -2.581043e-04
## ASV8195     -2.293684e-04 -2.386276e-04 -2.481961e-04 -2.580795e-04
## ASV8923      1.442144e-04  1.512258e-04  1.585754e-04  1.662784e-04
## ASV9666     -2.029804e-04 -2.110418e-04 -2.193609e-04 -2.279412e-04
## ASV1482      2.105848e-04  2.201365e-04  2.300965e-04  2.404795e-04
## ASV2726      2.792703e-04  2.923066e-04  3.059330e-04  3.201741e-04
## ASV3281     -2.293478e-04 -2.386055e-04 -2.481725e-04 -2.580543e-04
## ASV4235     -2.293281e-04 -2.385843e-04 -2.481495e-04 -2.580295e-04
## ASV4808      3.411074e-04  3.556612e-04  3.707678e-04  3.864426e-04
## ASV4861     -3.437191e-04 -3.585432e-04 -3.739469e-04 -3.899484e-04
## ASV5276      3.363173e-04  3.506001e-04  3.654181e-04  3.807857e-04
## ASV5837      2.957400e-04  3.094019e-04  3.236773e-04  3.385922e-04
## ASV7098      3.023087e-04  3.162273e-04  3.307673e-04  3.459547e-04
## ASV8451     -2.292370e-04 -2.384853e-04 -2.480421e-04 -2.579130e-04
## ASV8694     -2.292174e-04 -2.384641e-04 -2.480192e-04 -2.578882e-04
## ASV0905     -1.246042e-04 -1.303472e-04 -1.363393e-04 -1.425897e-04
## ASV2900      2.825392e-04  2.942833e-04  3.064498e-04  3.190490e-04
## ASV3963     -2.227559e-04 -2.317069e-04 -2.409533e-04 -2.505002e-04
## ASV0041     -2.535717e-04 -2.652582e-04 -2.774620e-04 -2.902038e-04
## ASV1865      2.612276e-04  2.738744e-04  2.871306e-04  3.010242e-04
## ASV1140      2.070061e-04  2.164846e-04  2.263728e-04  2.366859e-04
## ASV1179      3.057770e-04  3.198570e-04  3.345612e-04  3.499149e-04
## ASV0279      4.280213e-04  4.470098e-04  4.667842e-04  4.873725e-04
## ASV0043     -4.193883e-05 -4.449866e-05 -4.722852e-05 -5.014026e-05
## ASV2097     -2.387714e-04 -2.490360e-04 -2.597005e-04 -2.707776e-04
## ASV0309     -1.183511e-04 -1.233537e-04 -1.285432e-04 -1.339246e-04
## ASV0607      5.268438e-04  5.512485e-04  5.767498e-04  6.033938e-04
## ASV0025     -5.512709e-04 -5.766548e-04 -6.031626e-04 -6.308396e-04
## ASV2284     -8.357272e-05 -8.647226e-05 -8.942510e-05 -9.242804e-05
## ASV0556      9.557004e-05  1.004150e-04  1.055103e-04  1.108689e-04
## ASV5040      1.917354e-04  1.992825e-04  2.070647e-04  2.150849e-04
## ASV2924     -2.053404e-04 -2.135197e-04 -2.219627e-04 -2.306735e-04
## ASV1331      6.645774e-04  6.942620e-04  7.251878e-04  7.573994e-04
## ASV0506     -3.001568e-04 -3.128092e-04 -3.259254e-04 -3.395167e-04
## ASV1514      5.027962e-04  5.255499e-04  5.492775e-04  5.740155e-04
## ASV2144      4.150570e-04  4.333090e-04  4.522974e-04  4.720463e-04
## ASV2265      5.571163e-04  5.820948e-04  6.081235e-04  6.352404e-04
## ASV5156      1.167153e-04  1.211776e-04  1.257646e-04  1.304761e-04
## ASV5534      9.331636e-05  9.663039e-05  1.000125e-04  1.034598e-04
## ASV5747     -2.327453e-05 -2.530080e-05 -2.749253e-05 -2.986180e-05
## ASV6657      2.474785e-04  2.579738e-04  2.688606e-04  2.801493e-04
## ASV0658     -2.818163e-04 -2.937493e-04 -3.061257e-04 -3.189570e-04
## ASV0716      6.765309e-05  7.036893e-05  7.317110e-05  7.606039e-05
## ASV1657      1.180257e-04  1.225022e-04  1.271004e-04  1.318199e-04
## ASV1885     -1.051684e-05 -1.186958e-05 -1.335091e-05 -1.497090e-05
## ASV2333      6.125267e-04  6.395775e-04  6.677331e-04  6.970311e-04
## ASV3375      2.234613e-04  2.327692e-04  2.424110e-04  2.523945e-04
## ASV4317      2.407631e-04  2.517178e-04  2.631515e-04  2.750836e-04
## ASV9599     -2.334863e-05 -2.538101e-05 -2.757930e-05 -2.995561e-05
## ASV0175     -8.189482e-04 -8.548509e-04 -8.921895e-04 -9.310096e-04
## ASV1032      2.408363e-04  2.508691e-04  2.612607e-04  2.720192e-04
## ASV1235      2.972703e-06  2.432226e-06  1.813406e-06  1.109121e-06
## ASV1262      7.235390e-04  7.555469e-04  7.888625e-04  8.235298e-04
## ASV1320      1.832081e-04  1.923163e-04  2.018850e-04  2.119377e-04
## ASV13797     2.679655e-04  2.796315e-04  2.917623e-04  3.043730e-04
## ASV1491      1.404063e-04  1.474508e-04  1.548511e-04  1.626244e-04
## ASV15014    -2.337749e-05 -2.541191e-05 -2.761234e-05 -2.999090e-05
## ASV1510      2.253580e-04  2.362008e-04  2.475592e-04  2.594564e-04
## ASV1551     -8.803029e-05 -9.177640e-05 -9.566214e-05 -9.969099e-05
## ASV1919     -8.512447e-06 -7.886298e-06 -7.151221e-06 -6.296949e-06
## ASV2114      1.300233e-04  1.353163e-04  1.407911e-04  1.464516e-04
## ASV21486    -2.336392e-05 -2.539657e-05 -2.759500e-05 -2.997131e-05
## ASV2448      3.655663e-04  3.812156e-04  3.974602e-04  4.143164e-04
## ASV2589      1.740204e-04  1.812659e-04  1.887712e-04  1.965422e-04
## ASV2608      2.959435e-04  3.089505e-04  3.224851e-04  3.365652e-04
## ASV2786      2.410090e-04  2.518984e-04  2.632597e-04  2.751121e-04
## ASV2827      3.059929e-04  3.192736e-04  3.330749e-04  3.474126e-04
## ASV2872      2.473998e-04  2.576365e-04  2.682310e-04  2.791906e-04
## ASV3125      2.969475e-04  3.095543e-04  3.226339e-04  3.361993e-04
## ASV3247      3.215517e-04  3.351805e-04  3.493158e-04  3.639708e-04
## ASV3451     -2.347374e-05 -2.551582e-05 -2.772446e-05 -3.011179e-05
## ASV3465     -4.538125e-05 -4.847620e-05 -5.178941e-05 -5.533571e-05
## ASV3809      1.867506e-04  1.945115e-04  2.025487e-04  2.108681e-04
## ASV4006      3.982285e-04  4.149583e-04  4.322943e-04  4.502503e-04
## ASV4046      2.865397e-04  2.986982e-04  3.113118e-04  3.243929e-04
## ASV4938     -2.536786e-05 -2.749834e-05 -2.979933e-05 -3.228316e-05
## ASV5435     -2.350435e-05 -2.554847e-05 -2.775923e-05 -3.014877e-05
## ASV5605      1.122238e-04  1.162866e-04  1.204397e-04  1.246799e-04
## ASV5635     -2.350765e-05 -2.555175e-05 -2.776245e-05 -3.015187e-05
## ASV5743      3.626525e-04  3.783393e-04  3.946402e-04  4.115741e-04
## ASV6627     -2.352589e-05 -2.557143e-05 -2.778364e-05 -3.017469e-05
## ASV6785     -2.352167e-05 -2.556664e-05 -2.777823e-05 -3.016856e-05
## ASV7368      4.029291e-04  4.212488e-04  4.403666e-04  4.603146e-04
## ASV9118      1.061566e-04  1.100639e-04  1.140656e-04  1.181596e-04
## ASV9135      8.181717e-05  8.452614e-05  8.727011e-05  9.004428e-05
## ASV9435      1.860624e-04  1.933549e-04  2.008656e-04  2.085953e-04
## ASV9671     -2.355423e-05 -2.560164e-05 -2.781580e-05 -3.020886e-05
## ASV0387     -4.008407e-04 -4.178914e-04 -4.355811e-04 -4.539266e-04
## ASV0454     -3.995559e-04 -4.167674e-04 -4.346422e-04 -4.531995e-04
## ASV0751     -2.612084e-04 -2.722315e-04 -2.836604e-04 -2.955049e-04
## ASV1081      1.067848e-04  1.115417e-04  1.164941e-04  1.216484e-04
## ASV1332      2.192752e-04  2.289062e-04  2.389243e-04  2.493420e-04
## ASV2659      3.507445e-04  3.666108e-04  3.831520e-04  4.003929e-04
## ASV2979      3.600826e-04  3.752198e-04  3.909077e-04  4.071594e-04
## ASV4184      1.429688e-04  1.482411e-04  1.536400e-04  1.591627e-04
## ASV6198      1.265890e-04  1.318490e-04  1.372978e-04  1.429399e-04
## ASV7454      2.355186e-04  2.454974e-04  2.558469e-04  2.665768e-04
## ASV8198      9.169784e-05  9.478786e-05  9.792359e-05  1.011002e-04
## ASV0855      5.329219e-04  5.570160e-04  5.821431e-04  6.083425e-04
## ASV10092     2.230750e-04  2.325491e-04  2.423801e-04  2.525779e-04
## ASV1532      2.917248e-04  3.052899e-04  3.194688e-04  3.342877e-04
## ASV2553      7.004738e-04  7.317683e-04  7.643703e-04  7.983268e-04
## ASV2741      2.836378e-04  2.968808e-04  3.107226e-04  3.251880e-04
## ASV4095      1.552802e-04  1.629440e-04  1.709853e-04  1.794218e-04
## ASV5295      2.033668e-04  2.115318e-04  2.199612e-04  2.286583e-04
## ASV5787     -2.363019e-05 -2.568335e-05 -2.790363e-05 -3.030318e-05
## ASV9455      2.713283e-04  2.829274e-04  2.949694e-04  3.074674e-04
## ASV10879     2.846054e-04  2.971969e-04  3.103080e-04  3.239575e-04
## ASV3997      2.011267e-04  2.107512e-04  2.208293e-04  2.313812e-04
## ASV6760      5.248619e-05  5.377637e-05  5.503389e-05  5.625095e-05
## ASV6990      2.042249e-04  2.127947e-04  2.216787e-04  2.308852e-04
## ASV9560      1.253321e-04  1.302856e-04  1.353948e-04  1.406613e-04
## ASV0220      1.124628e-04  1.173737e-04  1.224777e-04  1.277802e-04
## ASV2518      2.753644e-04  2.877880e-04  3.007417e-04  3.142454e-04
## ASV3615      4.318507e-04  4.508803e-04  4.706837e-04  4.912871e-04
## ASV0075      9.182317e-05  9.536114e-05  9.899645e-05  1.027282e-04
## ASV8070      4.891296e-05  5.015214e-05  5.136563e-05  5.254660e-05
## ASV1658      2.033041e-04  2.119402e-04  2.209005e-04  2.301936e-04
## ASV0773      3.282058e-04  3.420900e-04  3.564875e-04  3.714111e-04
## ASV0799      1.054948e-05  1.100122e-05  1.146986e-05  1.195577e-05
## ASV1839     -6.326906e-05 -6.552197e-05 -6.781597e-05 -7.014763e-05
## ASV0265      3.219856e-04  3.372421e-04  3.532098e-04  3.699201e-04
## ASV3741      1.283691e-04  1.340493e-04  1.399616e-04  1.461141e-04
## ASV0847      4.465803e-04  4.664138e-04  4.870636e-04  5.085577e-04
## ASV1026      4.762467e-04  4.971925e-04  5.189818e-04  5.416420e-04
## ASV1222     -1.482640e-04 -1.540862e-04 -1.600866e-04 -1.662667e-04
## ASV0729      6.491319e-05  6.772644e-05  7.064902e-05  7.368406e-05
## ASV0143     -3.595960e-04 -3.747548e-04 -3.904680e-04 -4.067488e-04
## ASV1328      9.179215e-05  9.554686e-05  9.942989e-05  1.034436e-04
## ASV9078     -9.812415e-05 -1.036167e-04 -1.094298e-04 -1.155820e-04
## ASV0027     -5.245595e-04 -5.485647e-04 -5.736192e-04 -5.997641e-04
## ASV0546     -2.262817e-04 -2.358334e-04 -2.457370e-04 -2.560013e-04
## ASV1136      5.810917e-04  6.067675e-04  6.334939e-04  6.613073e-04
## ASV3081      2.783298e-04  2.908790e-04  3.039669e-04  3.176146e-04
## ASV0531      1.245379e-04  1.304326e-04  1.365991e-04  1.430486e-04
## ASV2525      1.581078e-04  1.648313e-04  1.718073e-04  1.790427e-04
## ASV1083     -5.857512e-05 -6.069173e-05 -6.285762e-05 -6.507183e-05
## ASV0424      1.040444e-04  1.087865e-04  1.137367e-04  1.189037e-04
## ASV0644      1.622399e-05  1.761845e-05  1.912433e-05  2.074944e-05
## ASV6007     -2.383838e-05 -2.591340e-05 -2.815787e-05 -3.058417e-05
## ASV0564      1.453691e-04  1.524172e-04  1.598048e-04  1.675475e-04
## ASV1938      1.524280e-04  1.586134e-04  1.650071e-04  1.716127e-04
## ASV6516     -3.547802e-04 -3.705296e-04 -3.869271e-04 -4.039949e-04
## ASV0503     -4.123776e-04 -4.296904e-04 -4.476297e-04 -4.662097e-04
## ASV6913     -4.097268e-04 -4.269327e-04 -4.447662e-04 -4.632427e-04
## ASV0164     -3.326829e-04 -3.482560e-04 -3.645436e-04 -3.815770e-04
## ASV1576      3.943784e-04  4.119147e-04  4.301797e-04  4.491994e-04
## ASV1725      1.940020e-04  2.033745e-04  2.131957e-04  2.234863e-04
## ASV4501      1.642759e-04  1.708519e-04  1.776393e-04  1.846409e-04
## ASV10678    -3.454619e-04 -3.606129e-04 -3.763708e-04 -3.927548e-04
## ASV0944      2.908390e-04  3.044403e-04  3.186630e-04  3.335339e-04
## ASV2292      4.483771e-04  4.680356e-04  4.884828e-04  5.097444e-04
## ASV1090      2.949674e-04  3.082273e-04  3.220502e-04  3.364572e-04
## ASV9117     -1.408261e-04 -1.463929e-04 -1.521342e-04 -1.580521e-04
## ASV0285     -1.772068e-04 -1.860125e-04 -1.952605e-04 -2.049726e-04
## ASV0463     -2.854383e-04 -2.976438e-04 -3.103110e-04 -3.234526e-04
## ASV3199      2.453357e-04  2.556113e-04  2.662595e-04  2.772894e-04
## ASV0150     -1.033761e-04 -1.084856e-04 -1.138498e-04 -1.194810e-04
## ASV6583     -1.453121e-04 -1.513117e-04 -1.575251e-04 -1.639576e-04
## ASV0392      2.363688e-04  2.470959e-04  2.582868e-04  2.699597e-04
## ASV14007    -2.843250e-04 -2.968283e-04 -3.098357e-04 -3.233636e-04
## ASV0177     -1.555384e-04 -1.620462e-04 -1.687890e-04 -1.757723e-04
## ASV6448     -1.261374e-04 -1.328268e-04 -1.398817e-04 -1.473218e-04
## ASV5399     -5.446451e-05 -5.791419e-05 -6.159135e-05 -6.551049e-05
## ASV0277     -5.914881e-05 -6.189185e-05 -6.475780e-05 -6.775167e-05
## ASV2599      9.271181e-05  9.562009e-05  9.854836e-05  1.014895e-04
## ASV13465    -7.344255e-05 -7.551860e-05 -7.758155e-05 -7.962317e-05
## ASV2412      1.479153e-04  1.546086e-04  1.615884e-04  1.688655e-04
## ASV0423      2.954526e-04  3.096904e-04  3.246181e-04  3.402691e-04
## ASV5187      1.767254e-04  1.837398e-04  1.909769e-04  1.984395e-04
## ASV0701     -6.795908e-04 -7.100973e-04 -7.418870e-04 -7.750061e-04
## ASV4248      1.647239e-04  1.726553e-04  1.809632e-04  1.896643e-04
## ASV0519      2.876335e-04  3.009991e-04  3.149652e-04  3.295567e-04
## ASV0764      5.102503e-05  5.378182e-05  5.669440e-05  5.977166e-05
## ASV5385     -3.581686e-04 -3.744006e-04 -3.913298e-04 -4.089827e-04
## ASV3021     -1.960424e-04 -2.035953e-04 -2.113659e-04 -2.193546e-04
## ASV4119     -1.086542e-04 -1.126939e-04 -1.168356e-04 -1.210778e-04
## ASV2534      5.768499e-05  6.014216e-05  6.269377e-05  6.534276e-05
## ASV1061      2.808804e-04  2.948960e-04  3.096288e-04  3.251161e-04
## ASV0670      3.818803e-04  3.991962e-04  4.172567e-04  4.360903e-04
## ASV1384      1.689575e-04  1.773288e-04  1.861187e-04  1.953476e-04
## ASV1981      3.566285e-04  3.729977e-04  3.900858e-04  4.079211e-04
## ASV9632     -1.125099e-04 -1.165129e-04 -1.206011e-04 -1.247715e-04
## ASV4564      8.812772e-05  9.222398e-05  9.650440e-05  1.009765e-04
## ASV5289     -7.913321e-05 -8.267561e-05 -8.636612e-05 -9.021001e-05
## ASV0516      7.232294e-04  7.558939e-04  7.899506e-04  8.254515e-04
## ASV1463     -2.580885e-04 -2.692004e-04 -2.807381e-04 -2.927131e-04
## ASV0969      1.194371e-04  1.244574e-04  1.296582e-04  1.350433e-04
## ASV1113     -3.368920e-04 -3.521050e-04 -3.679683e-04 -3.845067e-04
## ASV1234     -1.652310e-05 -1.818811e-05 -2.000495e-05 -2.198616e-05
## ASV3814      4.561291e-05  4.655020e-05  4.743685e-05  4.826420e-05
## ASV1000      3.420029e-04  3.569434e-04  3.724766e-04  3.886211e-04
## ASV0079     -3.326592e-05 -3.534825e-05 -3.757075e-05 -3.994310e-05
## ASV0145      1.144128e-04  1.190589e-04  1.238612e-04  1.288226e-04
## ASV0457     -4.297652e-04 -4.483455e-04 -4.676479e-04 -4.876935e-04
## ASV1485      1.424821e-04  1.491652e-04  1.561569e-04  1.634710e-04
## ASV0535     -9.458121e-05 -9.865062e-05 -1.028808e-04 -1.072773e-04
## ASV0259     -2.825791e-04 -2.950555e-04 -3.080358e-04 -3.215361e-04
## ASV0570      2.345542e-05  2.503417e-05  2.672407e-05  2.853277e-05
## ASV0906      3.666895e-04  3.827276e-04  3.994046e-04  4.167409e-04
## ASV1748     -2.222460e-04 -2.332352e-04 -2.447715e-04 -2.568813e-04
## ASV5520     -1.339450e-04 -1.410706e-04 -1.485895e-04 -1.565234e-04
## ASV2288     -4.180091e-04 -4.357828e-04 -4.542206e-04 -4.733397e-04
## ASV1887     -8.418435e-05 -8.882873e-05 -9.373816e-05 -9.892740e-05
## ASV0374     -1.321799e-04 -1.376920e-04 -1.434005e-04 -1.493096e-04
## ASV0823      4.127542e-04  4.305274e-04  4.489871e-04  4.681534e-04
## ASV0717      2.101832e-04  2.197981e-04  2.298345e-04  2.403091e-04
## ASV0431      1.429580e-04  1.490598e-04  1.553909e-04  1.619572e-04
## ASV1030      6.107868e-04  6.392766e-04  6.690599e-04  7.001917e-04
## ASV1082     -8.866059e-05 -9.266516e-05 -9.684010e-05 -1.011916e-04
## ASV2684      5.970753e-05  6.316865e-05  6.683752e-05  7.072612e-05
## ASV0051      5.411980e-04  5.661016e-04  5.921114e-04  6.192727e-04
## ASV0513      2.333499e-05  2.453172e-05  2.579237e-05  2.712049e-05
## ASV0581      6.844217e-04  7.154424e-04  7.477956e-04  7.815318e-04
## ASV7282      1.236421e-04  1.300584e-04  1.368235e-04  1.439572e-04
## ASV3009     -3.747646e-04 -3.916469e-04 -4.092451e-04 -4.275858e-04
## ASV2106     -1.873394e-04 -1.951393e-04 -2.032178e-04 -2.115811e-04
## ASV1012      1.224728e-04  1.284923e-04  1.348097e-04  1.414392e-04
## ASV0921     -7.192927e-06 -7.334583e-06 -7.465997e-06 -7.585362e-06
## ASV0010     -5.372451e-04 -5.620370e-04 -5.879317e-04 -6.149743e-04
## ASV1178      1.213248e-05  1.290810e-05  1.373384e-05  1.461267e-05
## ASV2848     -2.853668e-04 -2.977856e-04 -3.106979e-04 -3.241197e-04
## ASV0586      7.769753e-04  8.123395e-04  8.492367e-04  8.877265e-04
## ASV4225      2.510813e-05  2.669080e-05  2.837141e-05  3.015512e-05
## ASV2156     -3.236729e-04 -3.383629e-04 -3.536869e-04 -3.696693e-04
## ASV9778     -2.030002e-04 -2.119733e-04 -2.213116e-04 -2.310272e-04
## ASV0493     -4.487606e-04 -4.684457e-04 -4.889226e-04 -5.102173e-04
## ASV3770      8.111175e-05  8.439847e-05  8.779820e-05  9.131359e-05
## ASV0470      5.505886e-04  5.754060e-04  6.012797e-04  6.282490e-04
## ASV0262     -2.339920e-04 -2.455407e-04 -2.576658e-04 -2.703955e-04
## ASV0998      3.385876e-04  3.540582e-04  3.702058e-04  3.870574e-04
## ASV7708     -9.141477e-05 -9.535656e-05 -9.945011e-05 -1.036997e-04
## ASV0453     -1.141553e-05 -1.189279e-05 -1.238988e-05 -1.290786e-05
## ASV0044      6.944381e-04  7.258926e-04  7.586994e-04  7.929103e-04
## ASV5490      1.076294e-04  1.122120e-04  1.169642e-04  1.218897e-04
## ASV2638      3.056667e-05  3.213523e-05  3.378278e-05  3.551274e-05
## ASV0829     -5.967557e-05 -6.184781e-05 -6.407174e-05 -6.634643e-05
## ASV0601      1.294379e-04  1.356607e-04  1.421836e-04  1.490207e-04
## ASV0234      3.007088e-04  3.141530e-04  3.281588e-04  3.427461e-04
## ASV0133      3.988880e-04  4.170369e-04  4.359737e-04  4.557290e-04
## ASV0323      4.253112e-04  4.451754e-04  4.659489e-04  4.876717e-04
## ASV0854     -3.084166e-05 -3.194908e-05 -3.307773e-05 -3.422604e-05
## ASV0110      5.367064e-04  5.614385e-04  5.872710e-04  6.142490e-04
## ASV0816      2.860478e-05  2.981271e-05  3.106630e-05  3.236698e-05
## ASV1031     -8.287405e-05 -8.641820e-05 -9.010082e-05 -9.392664e-05
## ASV0144     -2.173951e-04 -2.271015e-04 -2.372126e-04 -2.477425e-04
## ASV0020     -1.031328e-04 -1.085737e-04 -1.143197e-04 -1.203888e-04
## ASV0962     -1.781467e-04 -1.861472e-04 -1.944845e-04 -2.031706e-04
## ASV0794      3.561408e-04  3.731749e-04  3.910163e-04  4.097017e-04
## ASV7117     -1.821595e-04 -1.904748e-04 -1.991549e-04 -2.082146e-04
## ASV1008     -1.312111e-04 -1.374837e-04 -1.440554e-04 -1.509405e-04
## ASV0096      5.782066e-04  6.048752e-04  6.327326e-04  6.618279e-04
## ASV0128     -3.488666e-04 -3.655777e-04 -3.830900e-04 -4.014418e-04
## ASV5232      2.623640e-04  2.745067e-04  2.871912e-04  3.004395e-04
## ASV0031      1.480747e-05  1.507746e-05  1.532256e-05  1.553855e-05
## ASV1744     -4.032354e-05 -4.230480e-05 -4.438925e-05 -4.658294e-05
## ASV0289      3.214222e-04  3.361404e-04  3.515081e-04  3.675517e-04
## ASV7413     -7.619130e-05 -8.057309e-05 -8.521841e-05 -9.014289e-05
## ASV0822     -3.834018e-04 -4.000827e-04 -4.174216e-04 -4.354390e-04
## ASV8111     -3.205592e-04 -3.337305e-04 -3.473582e-04 -3.614515e-04
## ASV0687      2.426080e-04  2.539847e-04  2.658816e-04  2.783209e-04
## ASV0112      7.097683e-05  7.306965e-05  7.514933e-05  7.720598e-05
## ASV0987      1.956379e-04  2.048410e-04  2.144699e-04  2.245436e-04
## ASV5332     -1.039563e-04 -1.080687e-04 -1.123140e-04 -1.166945e-04
## ASV1129     -2.544849e-04 -2.661817e-04 -2.783990e-04 -2.911583e-04
## ASV1274     -8.350465e-05 -8.734561e-05 -9.135649e-05 -9.554415e-05
## ASV0119      4.709103e-04  4.925904e-04  5.152332e-04  5.388781e-04
## ASV0890      1.200997e-04  1.258341e-04  1.318406e-04  1.381317e-04
## ASV0848      6.738483e-04  7.045135e-04  7.365076e-04  7.698822e-04
## ASV5944     -3.469852e-04 -3.616818e-04 -3.769235e-04 -3.927241e-04
## ASV19741    -3.522785e-04 -3.681849e-04 -3.847715e-04 -4.020643e-04
## ASV0504     -4.014043e-04 -4.189863e-04 -4.372737e-04 -4.562892e-04
## ASV2146     -2.638933e-04 -2.755910e-04 -2.877764e-04 -3.004679e-04
## ASV0089     -2.232898e-04 -2.338624e-04 -2.449283e-04 -2.565095e-04
## ASV2301     -2.351690e-04 -2.460181e-04 -2.573508e-04 -2.691870e-04
## ASV2982      7.166119e-05  7.520303e-05  7.891458e-05  8.280279e-05
## ASV0891     -2.966499e-04 -3.101119e-04 -3.241548e-04 -3.388010e-04
## ASV0093      4.815794e-04  5.034127e-04  5.261864e-04  5.499367e-04
## ASV0042      2.266363e-04  2.366128e-04  2.469925e-04  2.577886e-04
## ASV0980      3.176167e-04  3.316134e-04  3.461767e-04  3.613252e-04
## ASV0069     -8.229109e-05 -8.638787e-05 -9.069452e-05 -9.522212e-05
## ASV1364     -5.737190e-05 -6.004052e-05 -6.283073e-05 -6.574786e-05
## ASV0524     -9.466125e-05 -9.931184e-05 -1.041951e-04 -1.093230e-04
## ASV0435      6.379909e-04  6.671757e-04  6.976403e-04  7.294357e-04
## ASV0517     -2.585718e-04 -2.702816e-04 -2.824935e-04 -2.952265e-04
## ASV3167     -1.125464e-04 -1.178578e-04 -1.234138e-04 -1.292248e-04
## ASV4280     -4.810811e-05 -5.057763e-05 -5.318119e-05 -5.592661e-05
## ASV1158      1.577136e-04  1.653840e-04  1.734241e-04  1.818504e-04
## ASV2214      1.208805e-04  1.264413e-04  1.322549e-04  1.383331e-04
## ASV0544     -1.434827e-04 -1.500863e-04 -1.569825e-04 -1.641832e-04
## ASV5326     -2.573089e-05 -2.684508e-05 -2.800309e-05 -2.920632e-05
## ASV3765     -3.691949e-04 -3.854078e-04 -4.022705e-04 -4.198038e-04
## ASV4646     -1.228879e-05 -1.357978e-05 -1.498604e-05 -1.651648e-05
## ASV0090      3.564113e-05  3.688286e-05  3.814499e-05  3.942548e-05
## ASV3680      3.464188e-04  3.611947e-04  3.765268e-04  3.924298e-04
## ASV0111      5.678135e-05  5.902641e-05  6.133902e-05  6.371925e-05
## ASV0768      2.185074e-04  2.285521e-04  2.390426e-04  2.499972e-04
## ASV4862     -1.230824e-05 -1.275886e-05 -1.321958e-05 -1.369002e-05
## ASV1742     -2.847529e-04 -2.970017e-04 -3.097246e-04 -3.229358e-04
## ASV3701     -5.091764e-05 -5.332511e-05 -5.584639e-05 -5.848686e-05
## ASV2386     -1.728421e-04 -1.805729e-04 -1.886257e-04 -1.970120e-04
## ASV0375     -4.019704e-04 -4.194962e-04 -4.377178e-04 -4.566570e-04
## ASV2796      1.070557e-04  1.116646e-04  1.164521e-04  1.214235e-04
## ASV1369      2.779820e-04  2.901597e-04  3.028285e-04  3.160047e-04
## ASV10272    -2.525297e-04 -2.637508e-04 -2.754338e-04 -2.875945e-04
## ASV10354    -2.525056e-04 -2.637245e-04 -2.754052e-04 -2.875633e-04
## ASV1067     -2.211866e-05 -2.323625e-05 -2.441236e-05 -2.565018e-05
## ASV1900      5.321189e-04  5.564894e-04  5.819303e-04  6.084843e-04
## ASV4079     -9.180275e-05 -9.613799e-05 -1.006738e-04 -1.054190e-04
## ASV4149      3.529728e-04  3.680701e-04  3.837388e-04  3.999944e-04
## ASV5140     -2.524813e-04 -2.636979e-04 -2.753761e-04 -2.875316e-04
## ASV10782    -1.064707e-05 -1.091722e-05 -1.118007e-05 -1.143374e-05
## ASV4273     -5.698658e-05 -5.927402e-05 -6.163298e-05 -6.406381e-05
## ASV8121      2.451077e-04  2.563429e-04  2.680743e-04  2.803222e-04
## ASV8438     -2.524604e-04 -2.636752e-04 -2.753515e-04 -2.875048e-04
## ASV9390     -2.524364e-04 -2.636490e-04 -2.753229e-04 -2.874737e-04
## ASV1340      3.523871e-04  3.686242e-04  3.855826e-04  4.032916e-04
## ASV2650     -3.738406e-04 -3.901930e-04 -4.071958e-04 -4.248692e-04
## ASV4674      1.927629e-04  2.014928e-04  2.105972e-04  2.200901e-04
## ASV10492    -1.693898e-05 -1.778586e-05 -1.867650e-05 -1.961322e-05
## ASV11430    -2.524009e-04 -2.636104e-04 -2.752809e-04 -2.874280e-04
## ASV12135    -2.523769e-04 -2.635842e-04 -2.752523e-04 -2.873968e-04
## ASV14970    -2.523528e-04 -2.635580e-04 -2.752237e-04 -2.873657e-04
## ASV1954      2.890681e-04  3.021562e-04  3.158047e-04  3.300345e-04
## ASV2613      4.511111e-04  4.714058e-04  4.925600e-04  5.146053e-04
## ASV2757      1.766357e-04  1.841824e-04  1.920142e-04  2.001387e-04
## ASV2909     -2.649563e-04 -2.770248e-04 -2.896170e-04 -3.027531e-04
## ASV2954     -5.000410e-05 -5.204750e-05 -5.415829e-05 -5.633720e-05
## ASV2969      2.510113e-04  2.626978e-04  2.749147e-04  2.876845e-04
## ASV3410      5.510971e-05  5.794393e-05  6.093076e-05  6.407881e-05
## ASV3575      1.329613e-04  1.390334e-04  1.453726e-04  1.519898e-04
## ASV4275      2.849853e-04  2.972532e-04  3.099915e-04  3.232134e-04
## ASV4652      5.198448e-05  5.465766e-05  5.747332e-05  6.043921e-05
## ASV4761      2.847977e-04  2.970740e-04  3.098212e-04  3.230525e-04
## ASV6003      2.250331e-04  2.357799e-04  2.470394e-04  2.588357e-04
## ASV6110     -2.524055e-04 -2.636156e-04 -2.752867e-04 -2.874346e-04
## ASV7427      1.657689e-04  1.732834e-04  1.811214e-04  1.892954e-04
## ASV8092     -2.523901e-04 -2.635989e-04 -2.752685e-04 -2.874148e-04
## ASV8169     -2.523661e-04 -2.635727e-04 -2.752399e-04 -2.873836e-04
## ASV9693      1.109935e-04  1.160605e-04  1.213484e-04  1.268659e-04
## ASV10913     1.234852e-04  1.293721e-04  1.355380e-04  1.419959e-04
## ASV1979     -4.084768e-05 -4.258866e-05 -4.439504e-05 -4.626855e-05
## ASV3772      3.129354e-04  3.268134e-04  3.412624e-04  3.563023e-04
## ASV0113      5.787011e-05  6.016406e-05  6.252618e-05  6.495626e-05
## ASV1800     -2.738462e-05 -2.870715e-05 -3.009196e-05 -3.154169e-05
## ASV2335     -3.131403e-04 -3.260208e-04 -3.393485e-04 -3.531325e-04
## ASV0692      1.097985e-04  1.149073e-04  1.202469e-04  1.258269e-04
## ASV1120      1.376592e-04  1.438714e-04  1.503479e-04  1.570987e-04
## ASV1434     -7.303360e-04 -7.633368e-04 -7.977487e-04 -8.336250e-04
## ASV0076     -8.636962e-05 -9.064715e-05 -9.514198e-05 -9.986544e-05
## ASV0361      5.551282e-04  5.806641e-04  6.073316e-04  6.351769e-04
## ASV2231     -1.899951e-04 -1.995004e-04 -2.094951e-04 -2.200049e-04
## ASV2018     -1.733641e-05 -1.860842e-05 -1.998061e-05 -2.146105e-05
## ASV1529      4.615008e-04  4.829101e-04  5.052852e-04  5.286669e-04
## ASV0841     -2.227184e-05 -2.308953e-05 -2.392518e-05 -2.477800e-05
## ASV2556     -2.752863e-04 -2.875752e-04 -3.003753e-04 -3.137043e-04
## ASV2777      3.447560e-04  3.594417e-04  3.746780e-04  3.904795e-04
## ASV0355      2.880167e-04  3.013408e-04  3.152635e-04  3.298104e-04
## ASV5169     -3.914774e-04 -4.090199e-04 -4.272981e-04 -4.463384e-04
## ASV3091      1.942156e-04  2.034266e-04  2.130708e-04  2.231682e-04
## ASV2435      2.757604e-04  2.879884e-04  3.007164e-04  3.139611e-04
## ASV6822     -1.781293e-04 -1.860445e-04 -1.942854e-04 -2.028632e-04
## ASV12605    -4.275867e-04 -4.467928e-04 -4.668089e-04 -4.876646e-04
## ASV0286     -2.861620e-04 -2.990606e-04 -3.125111e-04 -3.265348e-04
## ASV0074     -2.098570e-05 -2.272303e-05 -2.460583e-05 -2.664591e-05
## ASV2485     -1.029773e-05 -1.046408e-05 -1.061330e-05 -1.074295e-05
## ASV1233     -5.482252e-04 -5.732194e-04 -5.993039e-04 -6.265221e-04
## ASV0356     -2.603853e-04 -2.719322e-04 -2.839556e-04 -2.964720e-04
## ASV2918     -3.117891e-04 -3.248781e-04 -3.384420e-04 -3.524923e-04
## ASV1427     -1.238999e-06 -1.490441e-06 -1.770616e-06 -2.082249e-06
## ASV1409      3.234161e-04  3.386575e-04  3.546088e-04  3.713023e-04
## ASV0770      9.572683e-05  9.944756e-05  1.032696e-04  1.071911e-04
## ASV1403     -3.839526e-04 -4.012292e-04 -4.192377e-04 -4.380051e-04
## ASV0314     -2.088096e-04 -2.182948e-04 -2.281887e-04 -2.385067e-04
## ASV0187      2.488085e-06  2.208358e-06  1.884481e-06  1.512367e-06
## ASV0313     -2.772640e-04 -2.894307e-04 -3.020854e-04 -3.152437e-04
## ASV1087      4.880899e-04  5.104349e-04  5.337619e-04  5.581105e-04
## ASV1970      2.483639e-05  2.575647e-05  2.669758e-05  2.765890e-05
## ASV0754      3.927620e-04  4.107434e-04  4.295154e-04  4.491101e-04
## ASV3775     -2.686490e-04 -2.811431e-04 -2.942035e-04 -3.078546e-04
## ASV0132      1.083709e-04  1.130476e-04  1.179031e-04  1.229419e-04
## ASV2329     -8.029237e-05 -8.473666e-05 -8.943817e-05 -9.441177e-05
## ASV0561      3.326808e-04  3.473227e-04  3.625548e-04  3.783960e-04
## ASV0130     -4.101906e-04 -4.288634e-04 -4.483450e-04 -4.686668e-04
## ASV0226      4.650530e-04  4.861585e-04  5.081734e-04  5.311325e-04
## ASV12648    -3.288522e-04 -3.435364e-04 -3.588376e-04 -3.747787e-04
## ASV0204      4.635429e-04  4.845697e-04  5.065016e-04  5.293732e-04
## ASV0767      7.439796e-05  7.715891e-05  7.998239e-05  8.286565e-05
## ASV0335     -2.544382e-04 -2.660945e-04 -2.782621e-04 -2.909614e-04
## ASV5901     -7.395629e-05 -7.692843e-05 -7.999751e-05 -8.316493e-05
## ASV0596     -9.507448e-05 -9.880239e-05 -1.026387e-04 -1.065829e-04
## ASV9271      9.822449e-05  1.033733e-04  1.088006e-04  1.145212e-04
## ASV0904      4.095079e-04  4.282808e-04  4.478804e-04  4.683400e-04
## ASV15270    -1.084696e-04 -1.137739e-04 -1.193330e-04 -1.251583e-04
## ASV0990     -1.194971e-04 -1.252103e-04 -1.311962e-04 -1.374676e-04
## ASV0155     -2.453602e-04 -2.563684e-04 -2.678401e-04 -2.797920e-04
## ASV0086     -5.636050e-07 -4.633141e-07 -3.475560e-07 -2.147845e-07
## ASV2581     -1.317958e-05 -1.337212e-05 -1.353472e-05 -1.366263e-05
## ASV1579     -2.930503e-04 -3.069093e-04 -3.214159e-04 -3.365995e-04
## ASV7730     -1.463029e-05 -1.588998e-05 -1.725060e-05 -1.871929e-05
## ASV0897      1.192812e-04  1.247623e-04  1.304857e-04  1.364612e-04
## ASV1975      5.585578e-04  5.838077e-04  6.101389e-04  6.375924e-04
## ASV0759     -1.279135e-05 -1.324121e-05 -1.369931e-05 -1.416505e-05
## ASV3082     -3.397360e-04 -3.552409e-04 -3.714227e-04 -3.883082e-04
## ASV3195     -5.950474e-04 -6.226641e-04 -6.515292e-04 -6.816961e-04
## ASV0427      3.125494e-04  3.271071e-04  3.423267e-04  3.582366e-04
## ASV2674      6.341197e-05  6.608756e-05  6.885779e-05  7.172415e-05
## ASV1500      9.633076e-05  1.006819e-04  1.052197e-04  1.099512e-04
## ASV0102     -3.582224e-04 -3.750299e-04 -3.926128e-04 -4.110056e-04
## ASV1217     -8.833342e-05 -9.205873e-05 -9.591803e-05 -9.991393e-05
## ASV4998     -3.731017e-05 -3.899709e-05 -4.075573e-05 -4.258869e-05
## ASV2890      5.052812e-04  5.277638e-04  5.511770e-04  5.755535e-04
## ASV0672     -2.209273e-04 -2.310590e-04 -2.416379e-04 -2.526823e-04
## ASV6960     -2.024731e-04 -2.122742e-04 -2.225454e-04 -2.333079e-04
## ASV0821      3.270909e-04  3.414338e-04  3.563531e-04  3.718677e-04
## ASV1995     -3.153251e-04 -3.297644e-04 -3.448377e-04 -3.605704e-04
## ASV0211     -1.800056e-04 -1.887748e-04 -1.979736e-04 -2.076227e-04
## ASV0364      1.844119e-04  1.929174e-04  2.018029e-04  2.110843e-04
## ASV3616      3.892828e-04  4.059061e-04  4.231569e-04  4.410519e-04
## ASV1996      4.447866e-04  4.648704e-04  4.858147e-04  5.076526e-04
## ASV1881     -7.274246e-05 -7.613170e-05 -7.967492e-05 -8.337869e-05
## ASV1089      4.335930e-04  4.531563e-04  4.735521e-04  4.948114e-04
## ASV1450     -8.838329e-05 -9.223286e-05 -9.623405e-05 -1.003914e-04
## ASV4643     -2.474638e-04 -2.585903e-04 -2.701866e-04 -2.822698e-04
## ASV3458      1.228268e-04  1.285123e-04  1.344453e-04  1.406347e-04
## ASV2543     -1.100270e-04 -1.152904e-04 -1.208053e-04 -1.265835e-04
## ASV3306     -1.240830e-04 -1.298204e-04 -1.358072e-04 -1.420522e-04
## ASV0218     -2.424077e-04 -2.535319e-04 -2.651488e-04 -2.772786e-04
## ASV3727      1.643372e-04  1.722942e-04  1.806394e-04  1.893916e-04
## ASV4394     -1.765659e-04 -1.849410e-04 -1.937087e-04 -2.028867e-04
## ASV2636      1.747637e-05  1.910753e-05  2.088492e-05  2.282094e-05
## ASV5116      4.331967e-05  4.520172e-05  4.715751e-05  4.918922e-05
## ASV1394     -4.312693e-04 -4.510047e-04 -4.716068e-04 -4.931106e-04
## ASV0656     -4.211813e-04 -4.400466e-04 -4.597031e-04 -4.801796e-04
## ASV0475      6.437073e-04  6.733302e-04  7.042677e-04  7.365738e-04
## ASV1042      1.604599e-04  1.677825e-04  1.754236e-04  1.833953e-04
## ASV1199     -3.328238e-04 -3.482842e-04 -3.644448e-04 -3.813358e-04
## ASV12962    -2.165454e-05 -2.252630e-05 -2.342594e-05 -2.435370e-05
## ASV0853      3.000358e-04  3.135851e-04  3.277083e-04  3.424261e-04
## ASV5069     -7.316144e-05 -7.752529e-05 -8.216373e-05 -8.709401e-05
## ASV7825     -1.876796e-04 -1.962705e-04 -2.052376e-04 -2.145960e-04
## ASV0339      2.102360e-04  2.198614e-04  2.299103e-04  2.404001e-04
## ASV2965      1.832569e-04  1.916764e-04  2.004675e-04  2.096453e-04
## ASV2347     -2.413623e-04 -2.519958e-04 -2.630608e-04 -2.745717e-04
## ASV0541      1.084639e-04  1.138390e-04  1.194860e-04  1.254189e-04
## ASV0369      2.841952e-04  2.970030e-04  3.103550e-04  3.242714e-04
## ASV0171      1.443173e-04  1.509384e-04  1.578533e-04  1.650742e-04
## ASV2235      3.417480e-04  3.563649e-04  3.715368e-04  3.872794e-04
## ASV5809     -3.234772e-04 -3.379435e-04 -3.530141e-04 -3.687104e-04
## ASV1267      4.080877e-04  4.264764e-04  4.456445e-04  4.656206e-04
## ASV0207     -4.389761e-04 -4.586571e-04 -4.791638e-04 -5.005260e-04
## ASV3126     -5.222630e-04 -5.464056e-04 -5.716291e-04 -5.979785e-04
## ASV0183     -5.736763e-04 -5.997196e-04 -6.268873e-04 -6.552229e-04
## ASV1792      1.953003e-04  2.038758e-04  2.127948e-04  2.220679e-04
## ASV2001     -5.082219e-04 -5.318149e-04 -5.564751e-04 -5.822485e-04
## ASV5732     -4.975883e-04 -5.201709e-04 -5.437266e-04 -5.682925e-04
## ASV2857     -3.161891e-04 -3.307695e-04 -3.460008e-04 -3.619101e-04
## ASV1052     -2.289727e-04 -2.391913e-04 -2.498381e-04 -2.609290e-04
## ASV3226     -1.464332e-04 -1.531168e-04 -1.600920e-04 -1.673705e-04
## ASV3766     -5.429090e-05 -5.680948e-05 -5.944201e-05 -6.219339e-05
## ASV0982     -1.598513e-04 -1.675214e-04 -1.755599e-04 -1.839844e-04
## ASV0489     -5.695156e-06 -6.486937e-06 -7.360053e-06 -8.321675e-06
## ASV3990     -5.427890e-04 -5.678099e-04 -5.939455e-04 -6.212419e-04
## ASV0433     -3.198502e-04 -3.340252e-04 -3.487786e-04 -3.641296e-04
## ASV0684     -1.401887e-04 -1.469399e-04 -1.540198e-04 -1.614446e-04
## ASV0063     -3.801278e-04 -3.973874e-04 -4.153902e-04 -4.341643e-04
## ASV1399      6.226187e-05  6.444963e-05  6.667313e-05  6.892837e-05
## ASV3093     -6.477116e-04 -6.777976e-04 -7.092461e-04 -7.421156e-04
## ASV1771      8.008772e-05  8.397828e-05  8.805952e-05  9.234078e-05
## ASV7910     -3.215510e-04 -3.352440e-04 -3.494505e-04 -3.641840e-04
## ASV3718     -4.322401e-04 -4.519883e-04 -4.726002e-04 -4.941101e-04
## ASV0039     -3.422787e-04 -3.584116e-04 -3.752919e-04 -3.929528e-04
## ASV6469     -7.052186e-04 -7.371440e-04 -7.704374e-04 -8.051504e-04
## ASV8186     -4.783525e-04 -5.001924e-04 -5.229862e-04 -5.467719e-04
## ASV1091     -4.937449e-05 -5.178645e-05 -5.431786e-05 -5.697469e-05
## ASV16930    -5.852471e-04 -6.120673e-04 -6.400676e-04 -6.692957e-04
## ASV7234     -4.380936e-04 -4.581312e-04 -4.790472e-04 -5.008766e-04
## ASV1560     -5.303329e-05 -5.554945e-05 -5.818379e-05 -6.094172e-05
## ASV2968      8.964498e-05  9.401568e-05  9.860290e-05  1.034176e-04
## ASV3824     -4.496174e-04 -4.699704e-04 -4.911972e-04 -5.133313e-04
## ASV0442     -2.814578e-04 -2.944720e-04 -3.080693e-04 -3.222738e-04
## ASV0677     -2.110477e-04 -2.200223e-04 -2.293315e-04 -2.389835e-04
## ASV4796     -2.983822e-04 -3.116942e-04 -3.255627e-04 -3.400080e-04
## ASV2206     -4.785939e-04 -5.005833e-04 -5.235457e-04 -5.475210e-04
## ASV2884      9.538158e-05  9.976977e-05  1.043522e-04  1.091368e-04
## ASV0482     -1.739704e-04 -1.820307e-04 -1.904541e-04 -1.992561e-04
## ASV1273      3.981922e-04  4.166251e-04  4.358809e-04  4.559932e-04
## ASV1910      5.124847e-05  5.322213e-05  5.524979e-05  5.733085e-05
## ASV0105      2.986574e-04  3.117296e-04  3.253223e-04  3.394519e-04
## ASV0149      3.189315e-04  3.334977e-04  3.487000e-04  3.645636e-04
## ASV5007     -4.974929e-04 -5.203869e-04 -5.442967e-04 -5.692641e-04
## ASV0757      4.299277e-04  4.497981e-04  4.705590e-04  4.922478e-04
## ASV11952    -3.543998e-04 -3.702245e-04 -3.867073e-04 -4.038714e-04
## ASV4102      2.836334e-04  2.966970e-04  3.103404e-04  3.245874e-04
## ASV1034      3.565959e-04  3.726847e-04  3.894603e-04  4.069487e-04
## ASV0753      2.651958e-04  2.772687e-04  2.898664e-04  3.030093e-04
## ASV2323      1.614547e-04  1.689816e-04  1.768512e-04  1.850782e-04
## ASV0881     -1.246953e-04 -1.301725e-04 -1.358682e-04 -1.417891e-04
## ASV3730     -3.327926e-04 -3.479024e-04 -3.636642e-04 -3.801030e-04
## ASV2685     -1.263464e-04 -1.317449e-04 -1.373449e-04 -1.431511e-04
## ASV3826     -6.312413e-05 -6.602554e-05 -6.905656e-05 -7.222275e-05
## ASV0689      3.034958e-05  3.205434e-05  3.386240e-05  3.578041e-05
## ASV4315     -4.369702e-04 -4.571089e-04 -4.781449e-04 -5.001156e-04
## ASV1239      2.077933e-04  2.165064e-04  2.255349e-04  2.348862e-04
## ASV3147     -7.316300e-05 -7.667680e-05 -8.035977e-05 -8.421999e-05
## ASV3454     -3.252062e-04 -3.399606e-04 -3.553514e-04 -3.714034e-04
## ASV4411     -1.952307e-04 -2.044908e-04 -2.141883e-04 -2.243436e-04
## ASV3007      3.876795e-04  4.049149e-04  4.228607e-04  4.415413e-04
## ASV6151     -3.138396e-04 -3.276406e-04 -3.420001e-04 -3.569369e-04
## ASV0834      3.327965e-04  3.482633e-04  3.644294e-04  3.813247e-04
## ASV1231      4.761466e-04  4.978317e-04  5.204583e-04  5.440630e-04
## ASV0643      4.013175e-04  4.195613e-04  4.385940e-04  4.584459e-04
## ASV0924      1.163443e-05  1.216297e-05  1.271255e-05  1.328359e-05
## ASV3238     -1.974043e-04 -2.061460e-04 -2.152447e-04 -2.247124e-04
## ASV1276     -2.332785e-04 -2.438698e-04 -2.549178e-04 -2.664398e-04
## ASV5503     -6.302436e-04 -6.586488e-04 -6.882598e-04 -7.191207e-04
## ASV0404      2.548765e-04  2.666797e-04  2.790130e-04  2.918984e-04
## ASV3430      4.170990e-05  4.446858e-05  4.742429e-05  5.059148e-05
## ASV5401     -2.702829e-04 -2.827245e-04 -2.957186e-04 -3.092878e-04
## ASV3426     -5.747508e-04 -6.008121e-04 -6.279949e-04 -6.563421e-04
## ASV0777      3.421732e-04  3.577218e-04  3.739426e-04  3.908614e-04
## ASV11093    -2.300942e-04 -2.405723e-04 -2.515060e-04 -2.629133e-04
## ASV2170     -1.993009e-04 -2.081162e-04 -2.172904e-04 -2.268353e-04
## ASV3861      1.798393e-04  1.875564e-04  1.955661e-04  2.038759e-04
## ASV1723     -3.350700e-04 -3.504358e-04 -3.664784e-04 -3.832248e-04
## ASV2460     -1.901820e-04 -1.990124e-04 -2.082416e-04 -2.178865e-04
## ASV1218     -2.738104e-04 -2.860038e-04 -2.987028e-04 -3.119252e-04
## ASV0436      1.603521e-05  1.635116e-05  1.664378e-05  1.690893e-05
## ASV0919      2.336926e-04  2.441885e-04  2.551278e-04  2.665266e-04
## ASV0577      9.984433e-05  1.042938e-04  1.089273e-04  1.137512e-04
## ASV2517      2.655017e-04  2.773346e-04  2.896576e-04  3.024875e-04
## ASV2628     -3.246544e-04 -3.396230e-04 -3.552566e-04 -3.715822e-04
## ASV1743     -2.967459e-04 -3.105914e-04 -3.250681e-04 -3.402034e-04
## ASV1678     -2.563646e-04 -2.684408e-04 -2.810784e-04 -2.943028e-04
## ASV0315      3.326363e-04  3.479282e-04  3.638976e-04  3.805725e-04
## ASV0253      1.546192e-04  1.616002e-04  1.688779e-04  1.764634e-04
## ASV1363      4.178400e-04  4.362475e-04  4.553975e-04  4.753137e-04
## ASV0995     -2.317588e-04 -2.424199e-04 -2.535542e-04 -2.651812e-04
## ASV4185     -1.001810e-04 -1.044291e-04 -1.088344e-04 -1.134009e-04
## ASV0782      2.121100e-04  2.221391e-04  2.326390e-04  2.436313e-04
## ASV3240     -2.516714e-04 -2.633638e-04 -2.755860e-04 -2.883610e-04
## ASV1392     -4.563379e-04 -4.774598e-04 -4.995312e-04 -5.225923e-04
## ASV8488     -1.038367e-04 -1.086628e-04 -1.137087e-04 -1.189841e-04
## ASV2814     -1.691333e-04 -1.769389e-04 -1.850944e-04 -1.936144e-04
## ASV0678     -3.458919e-04 -3.622901e-04 -3.794608e-04 -3.974395e-04
## ASV1295     -2.406815e-04 -2.517307e-04 -2.632684e-04 -2.753145e-04
## ASV7517     -1.449723e-04 -1.512787e-04 -1.578326e-04 -1.646414e-04
## ASV2996     -4.679576e-04 -4.891228e-04 -5.111936e-04 -5.342040e-04
## ASV2882     -4.391730e-04 -4.588909e-04 -4.794408e-04 -5.008531e-04
## ASV1317      2.715263e-04  2.840372e-04  2.971039e-04  3.107490e-04
## ASV9106     -4.482726e-04 -4.688347e-04 -4.903035e-04 -5.127155e-04
## ASV9688     -4.265347e-04 -4.460818e-04 -4.664886e-04 -4.877894e-04
## ASV6181     -4.254223e-04 -4.448451e-04 -4.651159e-04 -4.862680e-04
## ASV2936      1.317332e-05  1.391826e-05  1.470843e-05  1.554673e-05
## ASV0192     -1.743465e-04 -1.819557e-04 -1.898633e-04 -1.980780e-04
## ASV2509     -2.162228e-04 -2.264808e-04 -2.372209e-04 -2.484652e-04
## ASV0863      7.409957e-04  7.738131e-04  8.079738e-04  8.435230e-04
## ASV2762     -1.917380e-04 -2.005638e-04 -2.097828e-04 -2.194116e-04
## ASV4904     -4.076051e-04 -4.262172e-04 -4.456422e-04 -4.659121e-04
## ASV0571      1.387058e-04  1.448972e-04  1.513491e-04  1.580713e-04
## ASV13304    -6.679067e-05 -7.031892e-05 -7.404375e-05 -7.797659e-05
## ASV6863     -9.261872e-05 -9.688888e-05 -1.013507e-04 -1.060123e-04
## ASV4844      3.585526e-05  3.796260e-05  4.020554e-05  4.259345e-05
## ASV10779    -4.469975e-04 -4.672794e-04 -4.884350e-04 -5.104980e-04
## ASV7921     -3.779160e-04 -3.952439e-04 -4.133356e-04 -4.322219e-04
## ASV8458     -3.928526e-04 -4.104812e-04 -4.288513e-04 -4.479896e-04
## ASV2593     -5.159069e-05 -5.348861e-05 -5.542747e-05 -5.740512e-05
## ASV4410     -2.144450e-04 -2.243271e-04 -2.346485e-04 -2.454273e-04
## ASV0593      5.520133e-04  5.778706e-04  6.049131e-04  6.331925e-04
## ASV2669      3.191546e-04  3.333237e-04  3.480741e-04  3.634253e-04
## ASV0868     -4.210035e-04 -4.402890e-04 -4.604226e-04 -4.814382e-04
## ASV3123     -1.496213e-04 -1.567924e-04 -1.643045e-04 -1.721733e-04
## ASV3482     -1.709721e-04 -1.786852e-04 -1.867261e-04 -1.951068e-04
## ASV2552     -4.697916e-04 -4.902717e-04 -5.115606e-04 -5.336829e-04
## ASV0723      5.351718e-04  5.585599e-04  5.828770e-04  6.081520e-04
## ASV0526     -3.581242e-04 -3.745153e-04 -3.916279e-04 -4.094912e-04
## ASV4623     -1.621843e-04 -1.697111e-04 -1.775773e-04 -1.857974e-04
## ASV2070     -4.989066e-04 -5.216491e-04 -5.453814e-04 -5.701424e-04
## ASV1198      1.243415e-05  1.293158e-05  1.344421e-05  1.397202e-05
## ASV3034      2.028896e-05  2.107535e-05  2.188439e-05  2.271607e-05
## ASV1208     -5.910246e-05 -6.177299e-05 -6.455824e-05 -6.746267e-05
## ASV4860      8.135622e-05  8.518267e-05  8.918538e-05  9.337198e-05
## ASV2493     -1.545997e-04 -1.616751e-04 -1.690617e-04 -1.767719e-04
## ASV4217     -1.052547e-04 -1.097283e-04 -1.143663e-04 -1.191723e-04
## ASV1516     -6.996724e-05 -7.376428e-05 -7.778244e-05 -8.203551e-05
## ASV1186      1.846724e-04  1.931385e-04  2.019778e-04  2.112052e-04
## ASV1906     -1.609086e-04 -1.683542e-04 -1.761346e-04 -1.842638e-04
## ASV8220     -2.627660e-05 -2.774459e-05 -2.930162e-05 -3.095353e-05
## ASV4227     -3.659602e-04 -3.826584e-04 -4.000849e-04 -4.182686e-04
## ASV1013      2.315661e-04  2.425960e-04  2.541468e-04  2.662423e-04
## ASV7952     -2.503018e-04 -2.622300e-04 -2.747242e-04 -2.878108e-04
## ASV5923     -2.833638e-04 -2.965094e-04 -3.102480e-04 -3.246049e-04
## ASV0190     -3.494950e-04 -3.651429e-04 -3.814456e-04 -3.984264e-04
## ASV0491     -3.961597e-05 -4.171768e-05 -4.393784e-05 -4.628353e-05
## ASV9535     -1.509053e-04 -1.578078e-04 -1.650120e-04 -1.725297e-04
## ASV9947     -1.150815e-04 -1.208531e-04 -1.269238e-04 -1.333096e-04
## ASV6518     -9.862862e-05 -1.031382e-04 -1.078457e-04 -1.127590e-04
## ASV1741     -1.020226e-04 -1.068364e-04 -1.118745e-04 -1.171468e-04
## ASV1874      1.894843e-04  1.977747e-04  2.063932e-04  2.153496e-04
## ASV2150      5.439908e-05  5.692012e-05  5.955459e-05  6.230725e-05
## ASV5262     -9.997560e-05 -1.044335e-04 -1.090763e-04 -1.139106e-04
## ASV1729     -3.625842e-04 -3.793206e-04 -3.968048e-04 -4.150678e-04
## ASV1522     -7.212360e-05 -7.593709e-05 -7.995946e-05 -8.420216e-05
## ASV3250      7.679764e-05  8.016410e-05  8.366512e-05  8.730494e-05
## ASV4338     -3.656972e-04 -3.824325e-04 -3.999023e-04 -4.181361e-04
## ASV1386      4.370328e-04  4.571307e-04  4.781194e-04  5.000353e-04
## ASV0694     -5.039538e-05 -5.295556e-05 -5.565178e-05 -5.849166e-05
## ASV2026      4.089411e-05  4.317240e-05  4.558706e-05  4.814673e-05
## ASV0191     -2.894007e-04 -3.022546e-04 -3.156365e-04 -3.295641e-04
## ASV1641      1.424651e-04  1.491985e-04  1.562443e-04  1.636162e-04
## ASV1326      7.075674e-04  7.398660e-04  7.735738e-04  8.087464e-04
## ASV4786     -2.171530e-05 -2.283645e-05 -2.401859e-05 -2.526521e-05
## ASV0342      1.787905e-04  1.872035e-04  1.960064e-04  2.052165e-04
## ASV3025     -2.046656e-04 -2.137342e-04 -2.231746e-04 -2.329992e-04
## ASV6533     -3.515469e-04 -3.672909e-04 -3.836951e-04 -4.007834e-04
## ASV1898      3.957825e-04  4.140161e-04  4.330582e-04  4.529414e-04
## ASV1940      2.242213e-04  2.344908e-04  2.452105e-04  2.563982e-04
## ASV4968     -4.098080e-04 -4.286941e-04 -4.484213e-04 -4.690241e-04
## ASV3401     -2.144906e-04 -2.242847e-04 -2.345069e-04 -2.451742e-04
## ASV3211      1.299733e-04  1.361881e-04  1.426988e-04  1.495191e-04
## ASV1489     -5.680113e-04 -5.938562e-04 -6.208202e-04 -6.489466e-04
## ASV4139     -3.333830e-04 -3.486502e-04 -3.645885e-04 -3.812248e-04
## ASV6059     -3.519158e-04 -3.680490e-04 -3.848934e-04 -4.024777e-04
## ASV0918      8.791358e-05  9.168250e-05  9.559393e-05  9.965157e-05
## ASV1449      3.418898e-04  3.575458e-04  3.738898e-04  3.909496e-04
## ASV5652     -2.348687e-04 -2.455942e-04 -2.567880e-04 -2.684685e-04
## ASV4091     -5.452733e-06 -5.185064e-06 -4.858975e-06 -4.468014e-06
## ASV7638     -2.173756e-04 -2.271215e-04 -2.372765e-04 -2.478553e-04
## ASV6525     -3.052445e-04 -3.187169e-04 -3.327386e-04 -3.473280e-04
## ASV8959     -3.180431e-04 -3.326867e-04 -3.479809e-04 -3.639525e-04
## ASV0699      2.425738e-04  2.536132e-04  2.651276e-04  2.771346e-04
## ASV2925      2.983908e-04  3.122083e-04  3.266469e-04  3.417326e-04
## ASV0618      6.658748e-05  6.984154e-05  7.325508e-05  7.683566e-05
## ASV2083      4.664111e-05  4.894949e-05  5.137482e-05  5.392316e-05
## ASV6192     -3.866901e-04 -4.042595e-04 -4.225878e-04 -4.417044e-04
## ASV8640     -4.372732e-04 -4.571653e-04 -4.779197e-04 -4.995698e-04
## ASV1103      1.788081e-04  1.867753e-04  1.950735e-04  2.037146e-04
## ASV4240     -1.983841e-05 -2.034779e-05 -2.084460e-05 -2.132540e-05
## ASV2180      1.137493e-04  1.189057e-04  1.242843e-04  1.298936e-04
## ASV9157     -2.801472e-04 -2.928488e-04 -3.060963e-04 -3.199103e-04
## ASV1307      5.515201e-04  5.769243e-04  6.034585e-04  6.311695e-04
## ASV4960     -1.365253e-04 -1.425575e-04 -1.488353e-04 -1.553669e-04
## ASV3930     -1.162721e-04 -1.214239e-04 -1.267875e-04 -1.323703e-04
## ASV1200     -2.414359e-04 -2.525804e-04 -2.642221e-04 -2.763816e-04
## ASV4676     -1.223697e-04 -1.279319e-04 -1.337348e-04 -1.397876e-04
## ASV6993     -4.537406e-04 -4.740995e-04 -4.953147e-04 -5.174171e-04
## ASV4813     -1.780771e-04 -1.861911e-04 -1.946573e-04 -2.034896e-04
## ASV4364     -5.855272e-04 -6.118842e-04 -6.393581e-04 -6.679899e-04
## ASV0141      2.303239e-04  2.400913e-04  2.502195e-04  2.607173e-04
## ASV3509      1.493622e-04  1.566273e-04  1.642513e-04  1.722521e-04
## ASV2751      2.479486e-04  2.593488e-04  2.712543e-04  2.836860e-04
## ASV4913     -2.533709e-04 -2.648403e-04 -2.768020e-04 -2.892748e-04
## ASV0138      6.284700e-04  6.571289e-04  6.870377e-04  7.182459e-04
## ASV7697     -1.756826e-04 -1.834310e-04 -1.914927e-04 -1.998779e-04
## ASV1602      8.872302e-05  9.230299e-05  9.599646e-05  9.980408e-05
## ASV5976     -3.519832e-04 -3.679875e-04 -3.846851e-04 -4.021030e-04
## ASV7525     -3.624419e-04 -3.788840e-04 -3.960349e-04 -4.139218e-04
## ASV4961      1.636729e-04  1.710646e-04  1.787704e-04  1.868017e-04
## ASV2546      4.396092e-04  4.588971e-04  4.789590e-04  4.998199e-04
## ASV0721     -2.671420e-04 -2.792765e-04 -2.919343e-04 -3.051355e-04
## ASV0542      2.453850e-04  2.565120e-04  2.681186e-04  2.802233e-04
## ASV3865      1.565670e-04  1.635312e-04  1.707826e-04  1.783312e-04
## ASV5571     -2.830337e-04 -2.954316e-04 -3.083233e-04 -3.217238e-04
## ASV6804      3.672304e-05  3.872197e-05  4.083788e-05  4.307811e-05
## ASV4424      2.642176e-04  2.763309e-04  2.889763e-04  3.021751e-04
## ASV3395      1.915512e-04  1.996487e-04  2.080436e-04  2.167432e-04
## ASV2394     -2.606220e-04 -2.725947e-04 -2.850973e-04 -2.981513e-04
## ASV8629     -2.605963e-04 -2.725667e-04 -2.850666e-04 -2.981178e-04
## ASV1018      2.358448e-04  2.466419e-04  2.579137e-04  2.696794e-04
## ASV6139     -5.277515e-04 -5.518544e-04 -5.770098e-04 -6.032592e-04
## ASV10411    -2.709323e-04 -2.833720e-04 -2.963615e-04 -3.099232e-04
## ASV3992     -1.056398e-04 -1.105802e-04 -1.157474e-04 -1.211515e-04
## ASV7131     -2.094287e-05 -2.194556e-05 -2.299681e-05 -2.409905e-05
## ASV3729     -4.331126e-05 -4.499849e-05 -4.673214e-05 -4.851147e-05
## ASV2197     -5.791635e-05 -6.048655e-05 -6.316258e-05 -6.594809e-05
## ASV2426     -2.710109e-04 -2.831230e-04 -2.957404e-04 -3.088812e-04
## ASV3669     -2.556590e-04 -2.676615e-04 -2.802193e-04 -2.933572e-04
## ASV1820      1.338704e-04  1.398902e-04  1.461639e-04  1.527005e-04
## ASV7081     -2.412677e-04 -2.523706e-04 -2.639672e-04 -2.760779e-04
## ASV7872     -3.057216e-04 -3.195207e-04 -3.339079e-04 -3.489051e-04
## ASV1670     -3.613993e-05 -3.755356e-05 -3.900691e-05 -4.049952e-05
## ASV0712      2.985954e-04  3.128519e-04  3.277867e-04  3.434317e-04
## ASV0474      4.513472e-04  4.708702e-04  4.911517e-04  5.122137e-04
## ASV1196      4.512428e-04  4.719450e-04  4.935605e-04  5.161262e-04
## ASV0845      2.830103e-04  2.957859e-04  3.091079e-04  3.229968e-04
## ASV12393    -5.752795e-04 -6.016496e-04 -6.291800e-04 -6.579170e-04
## ASV5867     -2.216148e-04 -2.318426e-04 -2.425260e-04 -2.536837e-04
## ASV17619    -8.454437e-05 -8.869045e-05 -9.304424e-05 -9.761644e-05
## ASV4686     -1.958783e-04 -2.049716e-04 -2.144763e-04 -2.244102e-04
## ASV3520     -3.181233e-04 -3.326440e-04 -3.477987e-04 -3.636127e-04
## ASV10800    -5.206388e-04 -5.445880e-04 -5.695993e-04 -5.957161e-04
## ASV2706      4.622908e-04  4.836610e-04  5.059879e-04  5.293114e-04
## ASV1227     -6.400770e-05 -6.680063e-05 -6.970379e-05 -7.272050e-05
## ASV2621      4.255242e-04  4.454963e-04  4.663906e-04  4.882480e-04
## ASV0460      9.546020e-05  1.000612e-04  1.048849e-04  1.099421e-04
## ASV1069     -3.473728e-04 -3.634816e-04 -3.803167e-04 -3.979088e-04
## ASV6939     -3.192981e-04 -3.337372e-04 -3.487944e-04 -3.644931e-04
## ASV2862     -4.442675e-04 -4.645218e-04 -4.856578e-04 -5.077101e-04
## ASV1021     -2.595666e-04 -2.711163e-04 -2.831429e-04 -2.956630e-04
## ASV3845      2.067915e-04  2.163296e-04  2.262918e-04  2.366955e-04
## ASV0732      1.818585e-04  1.904270e-04  1.993938e-04  2.087766e-04
## ASV10731     1.391912e-04  1.454483e-04  1.519692e-04  1.587636e-04
## ASV3378      1.651647e-04  1.723022e-04  1.797149e-04  1.874107e-04
## ASV7154      1.211333e-05  1.229540e-05  1.245073e-05  1.257503e-05
## ASV9876      7.804100e-05  8.175001e-05  8.563398e-05  8.970094e-05
## ASV0631      3.493736e-04  3.657192e-04  3.828154e-04  4.006954e-04
## ASV13027    -2.640588e-04 -2.763540e-04 -2.892085e-04 -3.026467e-04
## ASV2497     -2.640325e-04 -2.763251e-04 -2.891769e-04 -3.026120e-04
## ASV3966     -3.724792e-04 -3.898675e-04 -4.080508e-04 -4.270639e-04
## ASV2574      2.199026e-04  2.295318e-04  2.395437e-04  2.499497e-04
## ASV0545     -2.069551e-04 -2.166607e-04 -2.268120e-04 -2.374283e-04
## ASV8453     -2.343571e-04 -2.452577e-04 -2.566535e-04 -2.685658e-04
## ASV0221     -1.238030e-04 -1.295217e-04 -1.354964e-04 -1.417379e-04
## ASV3305      1.678504e-04  1.757812e-04  1.840832e-04  1.927734e-04
## ASV2647     -1.145430e-04 -1.196179e-04 -1.249000e-04 -1.303964e-04
## ASV5789     -5.347342e-04 -5.596952e-04 -5.857974e-04 -6.130909e-04
## ASV1731     -1.668173e-04 -1.739274e-04 -1.813038e-04 -1.889535e-04
## ASV3857      7.437443e-05  7.767703e-05  8.111576e-05  8.469532e-05
## ASV0405      3.123441e-04  3.261543e-04  3.405265e-04  3.554792e-04
## ASV0094     -3.555436e-04 -3.707053e-04 -3.864398e-04 -4.027629e-04
## ASV0158     -1.200236e-05 -1.225928e-05 -1.250306e-05 -1.273123e-05
## ASV5507     -3.143771e-04 -3.287580e-04 -3.437699e-04 -3.594382e-04
## ASV1023     -1.206518e-06 -8.013023e-07 -3.350883e-07  1.986228e-07
## ASV0488     -2.045794e-04 -2.139756e-04 -2.237869e-04 -2.340301e-04
## ASV1459      1.706078e-04  1.780699e-04  1.858300e-04  1.938975e-04
## ASV4349     -5.082359e-05 -5.290730e-05 -5.506090e-05 -5.728535e-05
## ASV1172      5.291896e-04  5.531187e-04  5.780714e-04  6.040861e-04
## ASV10187    -1.399289e-04 -1.465524e-04 -1.534871e-04 -1.607473e-04
## ASV7227      8.264654e-05  8.651376e-05  9.055872e-05  9.478929e-05
## ASV10340     8.132576e-05  8.521858e-05  8.929840e-05  9.357424e-05
## ASV10821    -1.500924e-04 -1.569386e-04 -1.640828e-04 -1.715366e-04
## ASV13810    -1.500777e-04 -1.569226e-04 -1.640652e-04 -1.715174e-04
## ASV3230     -1.205878e-04 -1.261069e-04 -1.318679e-04 -1.378802e-04
## ASV5524      1.215881e-05  1.259073e-05  1.303022e-05  1.347658e-05
## ASV8742     -1.500520e-04 -1.568945e-04 -1.640345e-04 -1.714838e-04
## ASV9188      3.297759e-04  3.443317e-04  3.594769e-04  3.752306e-04
## ASV4658      1.680083e-04  1.756907e-04  1.837089e-04  1.920763e-04
## ASV7889      2.030721e-04  2.119051e-04  2.210866e-04  2.306274e-04
## ASV1466      4.899993e-05  5.165937e-05  5.447298e-05  5.745023e-05
## ASV1424     -9.418450e-05 -9.772525e-05 -1.013514e-04 -1.050600e-04
## ASV0098     -2.592257e-04 -2.713022e-04 -2.839265e-04 -2.971218e-04
## ASV0067     -4.132955e-04 -4.321942e-04 -4.519202e-04 -4.725065e-04
## ASV9434     -1.714045e-04 -1.791823e-04 -1.872953e-04 -1.957561e-04
## ASV3270     -6.825446e-05 -7.150714e-05 -7.491341e-05 -7.848024e-05
## ASV4518     -2.932418e-04 -3.064292e-04 -3.201739e-04 -3.344962e-04
## ASV7661     -2.750176e-04 -2.871319e-04 -2.997352e-04 -3.128434e-04
## ASV4223      3.173092e-05  3.322343e-05  3.478423e-05  3.641617e-05
## ASV3481      2.384118e-04  2.500538e-04  2.622748e-04  2.751040e-04
## ASV7819     -4.340103e-04 -4.538477e-04 -4.745540e-04 -4.961640e-04
## ASV3095     -1.822259e-05 -1.895856e-05 -1.971700e-05 -2.049779e-05
## ASV4476     -8.964344e-05 -9.389353e-05 -9.834388e-05 -1.030038e-04
## ASV1713      2.600486e-04  2.714134e-04  2.832294e-04  2.955105e-04
## ASV11165    -6.768867e-05 -7.056156e-05 -7.353940e-05 -7.662442e-05
## ASV2179      5.379348e-04  5.625930e-04  5.883366e-04  6.152093e-04
## ASV3747      4.610792e-04  4.821851e-04  5.042166e-04  5.272106e-04
## ASV1410      2.381950e-05  2.461177e-05  2.541244e-05  2.621956e-05
## ASV6069     -2.897213e-04 -3.030085e-04 -3.168816e-04 -3.313645e-04
## ASV1939      8.101681e-05  8.492609e-05  8.902522e-05  9.332340e-05
## ASV7865     -4.514083e-04 -4.720556e-04 -4.936071e-04 -5.160986e-04
## ASV4488     -4.156823e-04 -4.349493e-04 -4.550844e-04 -4.761243e-04
## ASV0938      3.277812e-04  3.426954e-04  3.582562e-04  3.744886e-04
## ASV7852     -2.483417e-04 -2.594743e-04 -2.710754e-04 -2.831621e-04
## ASV2503     -2.407215e-05 -2.543383e-05 -2.688053e-05 -2.841813e-05
## ASV2993     -3.558328e-04 -3.722834e-04 -3.894707e-04 -4.074255e-04
## ASV3752     -4.364586e-05 -4.557882e-05 -4.759086e-05 -4.968467e-05
## ASV2557     -3.625694e-04 -3.793459e-04 -3.968731e-04 -4.151821e-04
## ASV6522     -7.448300e-05 -7.777436e-05 -8.119937e-05 -8.476242e-05
## ASV0088     -2.667298e-04 -2.782044e-04 -2.901173e-04 -3.024805e-04
## ASV7935     -2.239216e-04 -2.340859e-04 -2.446888e-04 -2.557472e-04
## ASV0942     -2.859148e-04 -2.991477e-04 -3.129741e-04 -3.274188e-04
## ASV7709     -3.328821e-04 -3.476614e-04 -3.630481e-04 -3.790629e-04
## ASV4588     -1.698984e-04 -1.772579e-04 -1.849041e-04 -1.928456e-04
## ASV5765     -4.761820e-04 -4.978610e-04 -5.204805e-04 -5.440772e-04
## ASV3562     -2.352099e-05 -2.430381e-05 -2.509352e-05 -2.588783e-05
## ASV9076     -3.644306e-04 -3.811377e-04 -3.985808e-04 -4.167898e-04
## ASV4707     -4.067729e-04 -4.254777e-04 -4.450114e-04 -4.654077e-04
## ASV2188      2.902479e-04  3.038047e-04  3.179820e-04  3.328068e-04
## ASV0613      5.468921e-05  5.747572e-05  6.040806e-05  6.349388e-05
## ASV0663     -1.834415e-04 -1.919135e-04 -2.007645e-04 -2.100101e-04
## ASV3361     -3.603580e-04 -3.758271e-04 -3.918862e-04 -4.085512e-04
## ASV1478      4.026612e-04  4.207939e-04  4.396953e-04  4.593938e-04
## ASV0213      2.238297e-04  2.339542e-04  2.445122e-04  2.555201e-04
## ASV7674     -1.222447e-04 -1.276942e-04 -1.333702e-04 -1.392808e-04
## ASV2137     -1.308814e-04 -1.366600e-04 -1.426728e-04 -1.489275e-04
## ASV8246     -1.092920e-04 -1.142046e-04 -1.193252e-04 -1.246615e-04
## ASV0047     -3.461099e-04 -3.615582e-04 -3.776490e-04 -3.944052e-04
## ASV6117      1.232655e-05  1.304436e-05  1.380701e-05  1.461739e-05
## ASV3349     -6.639494e-05 -6.943886e-05 -7.261677e-05 -7.593405e-05
## ASV10881    -2.275148e-04 -2.379237e-04 -2.487885e-04 -2.601271e-04
## ASV6979     -1.540674e-04 -1.612269e-04 -1.687103e-04 -1.765315e-04
## ASV7930     -2.972200e-04 -3.107297e-04 -3.248241e-04 -3.395257e-04
## ASV7322      9.997986e-05  1.045919e-04  1.094093e-04  1.144406e-04
## ASV4927     -5.086230e-05 -5.332932e-05 -5.591700e-05 -5.863121e-05
## ASV9054     -1.657768e-04 -1.732372e-04 -1.810145e-04 -1.891205e-04
## ASV2692     -1.301092e-04 -1.364308e-04 -1.430579e-04 -1.500045e-04
## ASV1666     -8.687881e-05 -9.041156e-05 -9.405922e-05 -9.782282e-05
## ASV4728      1.900925e-04  1.985251e-04  2.073051e-04  2.164446e-04
## ASV3097      1.278179e-04  1.338327e-04  1.401269e-04  1.467130e-04
## ASV4962     -1.036597e-04 -1.088116e-04 -1.142258e-04 -1.199159e-04
## ASV5057      1.569049e-04  1.643405e-04  1.721263e-04  1.802786e-04
## ASV2639      2.835877e-04  2.969536e-04  3.109412e-04  3.255784e-04
## ASV1808     -3.566662e-05 -3.787011e-05 -4.021995e-05 -4.272613e-05
## ASV6333     -5.438541e-05 -5.721563e-05 -6.020139e-05 -6.335175e-05
## ASV4328     -1.263113e-04 -1.320677e-04 -1.380742e-04 -1.443409e-04
## ASV7707     -3.710798e-04 -3.877610e-04 -4.051459e-04 -4.232602e-04
## ASV11022    -3.598355e-04 -3.759517e-04 -3.927432e-04 -4.102341e-04
## ASV1469     -6.728794e-05 -7.030242e-05 -7.344378e-05 -7.671671e-05
## ASV3919     -1.251785e-04 -1.311029e-04 -1.373043e-04 -1.437953e-04
## ASV4038     -2.522972e-04 -2.637522e-04 -2.757018e-04 -2.881653e-04
## ASV4048      9.135034e-05  9.583200e-05  1.005370e-04  1.054764e-04
## ASV0634      1.048284e-04  1.097573e-04  1.149156e-04  1.203136e-04
## ASV1852     -2.861702e-04 -2.997438e-04 -3.139563e-04 -3.288371e-04
## ASV2505      2.138435e-04  2.235815e-04  2.337436e-04  2.443468e-04
## ASV1762     -3.280259e-04 -3.428957e-04 -3.584054e-04 -3.745794e-04
## ASV3761     -2.785107e-04 -2.911752e-04 -3.043879e-04 -3.181701e-04
## ASV0775     -4.721942e-04 -4.936164e-04 -5.159612e-04 -5.392640e-04
## ASV10911    -3.461114e-04 -3.617713e-04 -3.781025e-04 -3.951306e-04
## ASV1339     -5.852982e-05 -6.108223e-05 -6.373453e-05 -6.648954e-05
## ASV5214     -7.852380e-05 -8.197877e-05 -8.557220e-05 -8.930836e-05
## ASV4945      9.184276e-05  9.608656e-05  1.005196e-04  1.051496e-04
## ASV5624     -7.365364e-05 -7.669086e-05 -7.983081e-05 -8.307484e-05
## ASV3429     -4.205559e-05 -4.380024e-05 -4.560657e-05 -4.747592e-05
## ASV8416     -4.117707e-05 -4.339560e-05 -4.574105e-05 -4.822099e-05
## ASV2400     -4.276023e-04 -4.471317e-04 -4.675143e-04 -4.887839e-04
## ASV3388     -1.402649e-04 -1.469067e-04 -1.538599e-04 -1.611385e-04
## ASV7089      8.600733e-05  8.965286e-05  9.343159e-05  9.734642e-05
## ASV3396     -1.418722e-04 -1.481692e-04 -1.547236e-04 -1.615439e-04
## ASV0343      2.060907e-04  2.161518e-04  2.267112e-04  2.377936e-04
## ASV5505     -2.598352e-04 -2.718895e-04 -2.844881e-04 -2.976543e-04
## ASV6721     -1.230665e-04 -1.289073e-04 -1.350237e-04 -1.414285e-04
## ASV0537      1.094676e-04  1.152540e-04  1.213635e-04  1.278150e-04
## ASV7753     -3.364756e-04 -3.519316e-04 -3.680713e-04 -3.849224e-04
## ASV5022     -2.835944e-05 -3.000148e-05 -3.174565e-05 -3.359854e-05
## ASV1073      4.701208e-04  4.917369e-04  5.143107e-04  5.378814e-04
## ASV1347     -1.357179e-06 -1.498020e-06 -1.653603e-06 -1.825471e-06
## ASV15032     1.409942e-04  1.471700e-04  1.535905e-04  1.602631e-04
## ASV18213    -1.367878e-06 -1.509657e-06 -1.666254e-06 -1.839219e-06
## ASV20691     1.206056e-04  1.262374e-04  1.321256e-04  1.382813e-04
## ASV4260     -6.189205e-05 -6.476083e-05 -6.776010e-05 -7.089567e-05
## ASV4923      1.047106e-04  1.095887e-04  1.146876e-04  1.200168e-04
## ASV7995     -1.381918e-06 -1.525017e-06 -1.683055e-06 -1.857591e-06
## ASV8960      2.101968e-04  2.197381e-04  2.296894e-04  2.400664e-04
## ASV10682     1.579972e-04  1.647279e-04  1.717083e-04  1.789443e-04
## ASV11911    -1.408242e-06 -1.553701e-06 -1.714301e-06 -1.891615e-06
## ASV14296     2.519345e-04  2.631271e-04  2.747788e-04  2.869051e-04
## ASV2314      1.472928e-04  1.546325e-04  1.623476e-04  1.704579e-04
## ASV3819      1.626432e-04  1.698721e-04  1.773971e-04  1.852279e-04
## ASV4517     -1.448588e-06 -1.597793e-06 -1.762477e-06 -1.944242e-06
## ASV8941      3.131776e-04  3.276708e-04  3.428144e-04  3.586356e-04
## ASV1444      1.467727e-06  1.618728e-06  1.785371e-06  1.969273e-06
## ASV5959      5.677017e-05  5.929703e-05  6.192688e-05  6.466291e-05
## ASV3623     -1.437939e-04 -1.502206e-04 -1.569164e-04 -1.638911e-04
## ASV0260      1.745333e-04  1.825991e-04  1.910264e-04  1.998302e-04
## ASV4401     -1.175259e-04 -1.234992e-04 -1.297810e-04 -1.363868e-04
## ASV2891     -3.810696e-04 -3.987253e-04 -4.171761e-04 -4.364558e-04
## ASV2778     -8.565453e-05 -8.959867e-05 -9.371816e-05 -9.802024e-05
## ASV8744      1.659990e-04  1.731896e-04  1.806615e-04  1.884232e-04
## ASV1079      3.420378e-04  3.571241e-04  3.728239e-04  3.891579e-04
## ASV19688     2.698117e-05  2.847952e-05  3.006774e-05  3.175160e-05
## ASV4039      4.398032e-05  4.631251e-05  4.877645e-05  5.138009e-05
## ASV4982     -2.579863e-04 -2.697162e-04 -2.819542e-04 -2.947200e-04
## ASV1071     -2.579612e-04 -2.696887e-04 -2.819241e-04 -2.946872e-04
## ASV7666     -2.579360e-04 -2.696612e-04 -2.818941e-04 -2.946544e-04
## ASV0502      3.615326e-04  3.781232e-04  3.954459e-04  4.135303e-04
## ASV3624     -2.583918e-04 -2.701532e-04 -2.824247e-04 -2.952262e-04
## ASV0403      3.612098e-05  3.759979e-05  3.912831e-05  4.070724e-05
## ASV4939     -2.583639e-04 -2.701227e-04 -2.823914e-04 -2.951898e-04
## ASV6297     -3.102228e-04 -3.245217e-04 -3.394570e-04 -3.550550e-04
## ASV6343      2.728195e-04  2.845154e-04  2.966564e-04  3.092548e-04
## ASV0954     -5.673115e-05 -5.895303e-05 -6.123753e-05 -6.358394e-05
## ASV10225    -1.134446e-04 -1.187964e-04 -1.243952e-04 -1.302515e-04
## ASV1584      4.492961e-04  4.697527e-04  4.910970e-04  5.133635e-04
## ASV1803      1.635469e-04  1.706352e-04  1.779974e-04  1.856410e-04
## ASV2576     -4.492403e-04 -4.696917e-04 -4.910304e-04 -5.132909e-04
## ASV3252      2.927393e-04  3.061999e-04  3.202566e-04  3.349335e-04
## ASV3463     -4.491942e-04 -4.696413e-04 -4.909754e-04 -5.132308e-04
## ASV3822     -3.428556e-04 -3.587792e-04 -3.754239e-04 -3.928208e-04
## ASV4926     -1.794761e-04 -1.871415e-04 -1.950938e-04 -2.033400e-04
## ASV5564     -1.161517e-04 -1.214495e-04 -1.269785e-04 -1.327481e-04
## ASV5595     -6.770845e-05 -7.077639e-05 -7.397665e-05 -7.731438e-05
## ASV16463    -2.625612e-04 -2.747180e-04 -2.874218e-04 -3.006957e-04
## ASV6277      2.630735e-04  2.754253e-04  2.883464e-04  3.018618e-04
## ASV1344      2.625491e-04  2.747047e-04  2.874072e-04  3.006798e-04
## ASV1869      1.657254e-04  1.729505e-04  1.804590e-04  1.882592e-04
## ASV8155     -1.418576e-04 -1.479880e-04 -1.543545e-04 -1.609638e-04
## ASV2502     -2.640842e-04 -2.760443e-04 -2.885176e-04 -3.015234e-04
## ASV6742     -8.117139e-05 -8.454796e-05 -8.804263e-05 -9.165753e-05
## ASV3124     -1.714572e-04 -1.792177e-04 -1.873134e-04 -1.957577e-04
## ASV17042    -3.005382e-04 -3.142038e-04 -3.284605e-04 -3.433312e-04
## ASV0248      4.158448e-04  4.345510e-04  4.540496e-04  4.743698e-04
## ASV4557      7.293579e-05  7.675426e-05  8.078054e-05  8.502605e-05
## ASV3507     -4.581391e-04 -4.792810e-04 -5.013665e-04 -5.244350e-04
## ASV1870      3.362008e-05  3.516145e-05  3.677065e-05  3.845039e-05
## ASV2447     -2.213109e-04 -2.316642e-04 -2.424938e-04 -2.538211e-04
## ASV0347      3.589213e-04  3.756103e-04  3.930566e-04  4.112931e-04
## ASV1855     -1.644477e-04 -1.720362e-04 -1.799637e-04 -1.882446e-04
## ASV0568      1.231118e-04  1.286723e-04  1.344705e-04  1.405153e-04
## ASV1620     -2.199105e-04 -2.299941e-04 -2.405217e-04 -2.515111e-04
## ASV0101     -1.751545e-04 -1.825534e-04 -1.902228e-04 -1.981690e-04
## ASV7751      1.674284e-04  1.755601e-04  1.840922e-04  1.930446e-04
## ASV9033     -3.013364e-04 -3.152737e-04 -3.298362e-04 -3.450504e-04
## ASV3438     -8.768273e-05 -9.181004e-05 -9.612945e-05 -1.006497e-04
## ASV0637     -2.808859e-04 -2.937556e-04 -3.071911e-04 -3.212153e-04
## ASV1181     -2.080166e-04 -2.176489e-04 -2.277139e-04 -2.382296e-04
## ASV13480    -2.617817e-04 -2.738572e-04 -2.864712e-04 -2.996457e-04
## ASV14220    -2.617558e-04 -2.738289e-04 -2.864402e-04 -2.996118e-04
## ASV1448     -1.914973e-04 -2.003970e-04 -2.096998e-04 -2.194229e-04
## ASV1457      1.745281e-04  1.822045e-04  1.901892e-04  1.984916e-04
## ASV1645      1.274012e-04  1.334040e-04  1.396857e-04  1.462590e-04
## ASV2300     -1.696750e-04 -1.773143e-04 -1.852767e-04 -1.935741e-04
## ASV2533      2.609898e-04  2.727053e-04  2.849135e-04  2.976320e-04
## ASV5059      6.315069e-05  6.572472e-05  6.838363e-05  7.112840e-05
## ASV8871     -2.617450e-04 -2.738170e-04 -2.864270e-04 -2.995973e-04
## ASV1289     -2.792177e-04 -2.918314e-04 -3.049838e-04 -3.186951e-04
## ASV3983     -1.199181e-04 -1.255588e-04 -1.314609e-04 -1.376358e-04
## ASV10323    -9.598329e-05 -1.007038e-04 -1.056610e-04 -1.108671e-04
## ASV13279    -2.616788e-04 -2.737445e-04 -2.863477e-04 -2.995105e-04
## ASV7149     -2.616530e-04 -2.737162e-04 -2.863167e-04 -2.994766e-04
## ASV1691      5.018027e-05  5.256685e-05  5.506737e-05  5.768737e-05
## ASV1649      1.289127e-04  1.349207e-04  1.412002e-04  1.477625e-04
## ASV10120     3.819873e-05  4.005177e-05  4.199600e-05  4.403600e-05
## ASV8285     -3.350533e-04 -3.508105e-04 -3.672959e-04 -3.845416e-04
## ASV0037     -2.876489e-04 -3.010747e-04 -3.151138e-04 -3.297928e-04
## ASV1770      7.492332e-05  7.836455e-05  8.195855e-05  8.571167e-05
## ASV2252      7.163661e-05  7.491382e-05  7.833421e-05  8.190337e-05
## ASV7580      2.877850e-04  3.005319e-04  3.137999e-04  3.276067e-04
## ASV5643     -2.646728e-04 -2.768390e-04 -2.895444e-04 -3.028109e-04
## ASV2722     -8.611408e-05 -9.034195e-05 -9.478236e-05 -9.944636e-05
## ASV2662     -1.818640e-04 -1.902928e-04 -1.991023e-04 -2.083090e-04
## ASV0479     -4.128664e-04 -4.314811e-04 -4.508881e-04 -4.711169e-04
## ASV2009     -4.333276e-04 -4.525394e-04 -4.725379e-04 -4.933494e-04
## ASV3731     -2.926055e-04 -3.057247e-04 -3.193947e-04 -3.336352e-04
## ASV5497     -3.629017e-04 -3.793974e-04 -3.966072e-04 -4.145586e-04
## ASV6647      1.530165e-05  1.581420e-05  1.633124e-05  1.685119e-05
## ASV8974     -2.671724e-04 -2.792387e-04 -2.918195e-04 -3.049340e-04
## ASV15527     2.307848e-05  2.404563e-05  2.504745e-05  2.608467e-05
## ASV6705     -1.676281e-04 -1.759332e-04 -1.846611e-04 -1.938337e-04
## ASV0354      3.427474e-04  3.584947e-04  3.749387e-04  3.921078e-04
## ASV2707      7.717935e-05  8.043813e-05  8.381507e-05  8.731270e-05
## ASV11167    -4.497554e-04 -4.702618e-04 -4.916602e-04 -5.139855e-04
## ASV6393     -3.581586e-04 -3.745584e-04 -3.916783e-04 -4.095472e-04
## ASV3808     -2.540947e-04 -2.654050e-04 -2.771846e-04 -2.894502e-04
## ASV9337      3.433980e-05  3.565161e-05  3.699636e-05  3.837304e-05
## ASV5043     -3.673805e-04 -3.841907e-04 -4.017380e-04 -4.200517e-04
## ASV4189     -9.728749e-06 -9.945148e-06 -1.014987e-05 -1.034050e-05
## ASV1304     -1.374892e-04 -1.432019e-04 -1.491149e-04 -1.552323e-04
## ASV2105     -1.926735e-04 -2.015238e-04 -2.107657e-04 -2.204153e-04
## ASV2421     -6.739292e-05 -7.057974e-05 -7.391660e-05 -7.741053e-05
## ASV3170      3.086816e-04  3.230359e-04  3.380418e-04  3.537273e-04
## ASV5036      4.121598e-04  4.309769e-04  4.506157e-04  4.711088e-04
## ASV2286      2.602435e-04  2.721826e-04  2.846487e-04  2.976632e-04
## ASV3363      2.615290e-04  2.738344e-04  2.867109e-04  3.001842e-04
## ASV5759     -2.443532e-05 -2.567447e-05 -2.697986e-05 -2.835530e-05
## ASV5440     -1.817426e-04 -1.904470e-04 -1.995684e-04 -2.091268e-04
## ASV2050      2.964930e-04  3.094288e-04  3.228727e-04  3.368393e-04
## ASV4478      2.144016e-04  2.245421e-04  2.351577e-04  2.462702e-04
## ASV5725     -2.288914e-04 -2.391911e-04 -2.499274e-04 -2.611164e-04
## ASV1600     -6.883227e-05 -7.260626e-05 -7.660111e-05 -8.083037e-05
## ASV1654     -4.076878e-04 -4.260780e-04 -4.452519e-04 -4.652388e-04
## ASV3781     -1.752691e-04 -1.830175e-04 -1.910808e-04 -1.994693e-04
## ASV7144     -1.503466e-04 -1.569472e-04 -1.638113e-04 -1.709473e-04
## ASV12710    -5.407254e-05 -5.612419e-05 -5.822742e-05 -6.038084e-05
## ASV3317      2.059398e-04  2.153275e-04  2.251256e-04  2.353506e-04
## ASV3249     -4.033951e-04 -4.217889e-04 -4.409829e-04 -4.610085e-04
## ASV0669     -2.499939e-04 -2.610095e-04 -2.724707e-04 -2.843919e-04
## ASV0893      1.484826e-04  1.551835e-04  1.621699e-04  1.694522e-04
## ASV11060    -1.484682e-04 -1.551678e-04 -1.621527e-04 -1.694334e-04
## ASV3207      5.157131e-04  5.398814e-04  5.651622e-04  5.916045e-04
## ASV3498     -1.484666e-04 -1.551660e-04 -1.621508e-04 -1.694314e-04
## ASV4358      9.424782e-05  9.853410e-05  1.030058e-04  1.076701e-04
## ASV4806      2.553810e-04  2.670176e-04  2.791594e-04  2.918261e-04
## ASV4941      1.484587e-04  1.551574e-04  1.621414e-04  1.694212e-04
## ASV6998      4.455364e-05  4.657916e-05  4.869182e-05  5.089489e-05
## ASV7327     -1.484477e-04 -1.551454e-04 -1.621282e-04 -1.694068e-04
## ASV5112      3.016855e-04  3.156743e-04  3.302924e-04  3.455659e-04
## ASV5345     -1.484212e-04 -1.551164e-04 -1.620966e-04 -1.693722e-04
## ASV8911     -1.484068e-04 -1.551007e-04 -1.620794e-04 -1.693535e-04
## ASV5061      3.474058e-04  3.632202e-04  3.797201e-04  3.969320e-04
## ASV1968     -3.135791e-05 -3.297425e-05 -3.467821e-05 -3.647482e-05
## ASV4669     -1.483803e-04 -1.550717e-04 -1.620478e-04 -1.693190e-04
## ASV6209     -5.411121e-05 -5.635097e-05 -5.866702e-05 -6.106036e-05
## ASV6938      2.945771e-04  3.077742e-04  3.215239e-04  3.358456e-04
## ASV6987      1.626593e-04  1.697057e-04  1.770252e-04  1.846255e-04
## ASV7842     -1.483732e-04 -1.550640e-04 -1.620394e-04 -1.693098e-04
## ASV17950     1.108171e-07  1.194041e-07  1.285367e-07  1.382309e-07
## ASV3380     -4.314654e-04 -4.507424e-04 -4.708230e-04 -4.917354e-04
## ASV13740    -3.702122e-04 -3.873126e-04 -4.051782e-04 -4.238408e-04
## ASV4313     -2.169765e-04 -2.269491e-04 -2.373628e-04 -2.482355e-04
## ASV3891     -2.219220e-04 -2.313250e-04 -2.410752e-04 -2.511810e-04
## ASV3322     -2.623756e-04 -2.743907e-04 -2.869342e-04 -3.000275e-04
## ASV1668     -4.577187e-05 -4.799834e-05 -5.033623e-05 -5.279148e-05
## ASV1739      1.002094e-04  1.045135e-04  1.089811e-04  1.136165e-04
## ASV3194      2.088206e-04  2.183274e-04  2.282469e-04  2.385953e-04
## ASV0071     -3.104263e-04 -3.236655e-04 -3.374011e-04 -3.516456e-04
## ASV0695      1.523686e-04  1.594900e-04  1.669342e-04  1.747146e-04
## ASV3835     -1.179418e-04 -1.231754e-04 -1.286237e-04 -1.342940e-04
## ASV1876      1.231084e-04  1.288586e-04  1.348712e-04  1.411575e-04
## ASV4892     -3.643410e-04 -3.810877e-04 -3.985761e-04 -4.168364e-04
## ASV1212     -1.252341e-04 -1.309263e-04 -1.368654e-04 -1.430612e-04
## ASV2640      1.365381e-06  1.348027e-06  1.322735e-06  1.288554e-06
## ASV7236     -3.606588e-04 -3.773417e-04 -3.947733e-04 -4.129849e-04
## ASV2353     -1.016523e-04 -1.065215e-04 -1.116246e-04 -1.169727e-04
## ASV0276      4.339895e-04  4.530249e-04  4.728245e-04  4.934133e-04
## ASV2262     -1.332963e-04 -1.393844e-04 -1.457401e-04 -1.523745e-04
## ASV11201    -9.006844e-05 -9.435756e-05 -9.884999e-05 -1.035552e-04
## ASV0665      3.569605e-05  3.726516e-05  3.889830e-05  4.059776e-05
## ASV5238      3.304750e-05  3.384342e-05  3.461021e-05  3.534117e-05
## ASV6885     -1.972280e-04 -2.061668e-04 -2.154901e-04 -2.252127e-04
## ASV1844      8.222061e-05  8.639863e-05  9.079744e-05  9.542916e-05
## ASV0379      2.572389e-04  2.688938e-04  2.810493e-04  2.937244e-04
## ASV1040     -7.959548e-05 -8.301072e-05 -8.655570e-05 -9.023389e-05
## ASV7913     -1.495048e-04 -1.563335e-04 -1.634602e-04 -1.708966e-04
## ASV1197     -2.571940e-04 -2.688448e-04 -2.809958e-04 -2.936660e-04
## ASV5918      1.118408e-04  1.169997e-04  1.223890e-04  1.280182e-04
## ASV8045      5.905012e-05  6.201749e-05  6.513819e-05  6.842025e-05
## ASV16458    -2.474605e-05 -2.564628e-05 -2.656462e-05 -2.749984e-05
## ASV10827    -2.571763e-04 -2.688256e-04 -2.809749e-04 -2.936432e-04
## ASV3658     -2.571513e-04 -2.687983e-04 -2.809451e-04 -2.936107e-04
## ASV0073     -5.355694e-04 -5.602855e-04 -5.861037e-04 -6.130694e-04
## ASV1951     -1.106261e-04 -1.162289e-04 -1.221250e-04 -1.283303e-04
## ASV7630     -3.397423e-04 -3.552228e-04 -3.713761e-04 -3.882287e-04
## ASV9449     -1.827092e-04 -1.913380e-04 -2.003689e-04 -2.098198e-04
## ASV3944      3.644606e-04  3.810101e-04  3.982754e-04  4.162843e-04
## ASV1520     -4.923707e-04 -5.145836e-04 -5.377415e-04 -5.618794e-04
## ASV0307      3.830595e-04  4.008541e-04  4.194540e-04  4.388936e-04
## ASV12731    -9.785932e-05 -1.025480e-04 -1.074624e-04 -1.126133e-04
## ASV0282      3.845914e-04  4.024563e-04  4.211297e-04  4.406460e-04
## ASV2646      3.405746e-04  3.555006e-04  3.710220e-04  3.871573e-04
## ASV3536      2.732988e-04  2.858039e-04  2.988573e-04  3.124807e-04
## ASV10089    -2.492882e-04 -2.602138e-04 -2.715754e-04 -2.833867e-04
## ASV1185      2.492648e-04  2.601883e-04  2.715477e-04  2.833565e-04
## ASV1452      2.492413e-04  2.601628e-04  2.715199e-04  2.833263e-04
## ASV1700      2.492179e-04  2.601373e-04  2.714922e-04  2.832961e-04
## ASV6948     -2.491945e-04 -2.601118e-04 -2.714644e-04 -2.832659e-04
## ASV0389     -3.258242e-04 -3.402165e-04 -3.551932e-04 -3.707735e-04
## ASV11884     4.992430e-06  5.646094e-06  6.365373e-06  7.155942e-06
## ASV23165    -2.491436e-04 -2.600564e-04 -2.714041e-04 -2.832003e-04
## ASV2841      2.491202e-04  2.600309e-04  2.713764e-04  2.831701e-04
## ASV2949      2.490968e-04  2.600055e-04  2.713486e-04  2.831399e-04
## ASV4037      2.490735e-04  2.599800e-04  2.713209e-04  2.831098e-04
## ASV4477      2.490501e-04  2.599545e-04  2.712932e-04  2.830796e-04
## ASV4496      2.490267e-04  2.599291e-04  2.712655e-04  2.830495e-04
## ASV5784     -2.490034e-04 -2.599036e-04 -2.712378e-04 -2.830193e-04
## ASV6035      7.676818e-06  8.303539e-06  8.982040e-06  9.716441e-06
## ASV6232     -2.494295e-04 -2.603483e-04 -2.717017e-04 -2.835032e-04
## ASV1818      2.489577e-04  2.598539e-04  2.711837e-04  2.829605e-04
## ASV2595      2.489343e-04  2.598285e-04  2.711560e-04  2.829304e-04
## ASV2788     -3.278286e-05 -3.423811e-05 -3.575283e-05 -3.732896e-05
## ASV5018      2.489130e-04  2.598052e-04  2.711307e-04  2.829028e-04
## ASV0127      3.414864e-04  3.573213e-04  3.738703e-04  3.911636e-04
## ASV1527      8.537306e-06  9.047174e-06  9.589685e-06  1.016698e-05
## ASV1055      1.929767e-04  2.017565e-04  2.109163e-04  2.204707e-04
## ASV4791      1.199733e-04  1.245268e-04  1.291970e-04  1.339816e-04
## ASV0859      1.373327e-04  1.434507e-04  1.498208e-04  1.564514e-04
## ASV12971    -3.683815e-04 -3.852519e-04 -4.028629e-04 -4.212439e-04
## ASV16856    -3.683454e-04 -3.852124e-04 -4.028196e-04 -4.211966e-04
## ASV7321     -3.010628e-04 -3.148767e-04 -3.292994e-04 -3.443554e-04
## ASV8780     -3.682804e-04 -3.851413e-04 -4.027419e-04 -4.211116e-04
## ASV1569      2.694745e-04  2.817352e-04  2.945274e-04  3.078718e-04
## ASV3696      4.294057e-05  4.479151e-05  4.671285e-05  4.870639e-05
## ASV0624      4.927705e-04  5.151268e-04  5.384488e-04  5.627743e-04
## ASV0495      2.993931e-04  3.127495e-04  3.266602e-04  3.411447e-04
## ASV16971    -1.504140e-04 -1.572933e-04 -1.644741e-04 -1.719683e-04
## ASV6535      8.689873e-05  9.113193e-05  9.557446e-05  1.002369e-04
## ASV1897      3.516213e-04  3.673704e-04  3.837800e-04  4.008738e-04
## ASV2631     -4.729147e-05 -4.980927e-05 -5.247011e-05 -5.528269e-05
## ASV6204      1.190528e-04  1.245939e-04  1.303861e-04  1.364400e-04
## ASV3312     -2.272380e-04 -2.376946e-04 -2.486162e-04 -2.600219e-04
## ASV3360      1.447747e-04  1.516115e-04  1.587671e-04  1.662559e-04
## ASV3907      7.054429e-05  7.391877e-05  7.745426e-05  8.115834e-05
## ASV6090      7.201465e-05  7.533732e-05  7.880733e-05  8.243058e-05
## ASV8652     -8.183698e-05 -8.538445e-05 -8.906975e-05 -9.289680e-05
## ASV11129    -1.484289e-04 -1.551308e-04 -1.621189e-04 -1.694041e-04
## ASV11073    -1.484145e-04 -1.551150e-04 -1.621017e-04 -1.693854e-04
## ASV1840      4.964186e-04  5.187403e-04  5.420044e-04  5.662450e-04
## ASV2298      1.868169e-04  1.951105e-04  2.037458e-04  2.127346e-04
## ASV2420      4.466913e-04  4.671765e-04  4.885648e-04  5.108927e-04
## ASV6474      6.167957e-05  6.462787e-05  6.771607e-05  7.095060e-05
## ASV8475     -1.483956e-04 -1.550944e-04 -1.620792e-04 -1.693609e-04
## ASV8679     -1.483812e-04 -1.550787e-04 -1.620620e-04 -1.693421e-04
## ASV6527      1.424878e-04  1.491385e-04  1.560933e-04  1.633654e-04
## ASV2504     -2.474699e-05 -2.609899e-05 -2.753010e-05 -2.904524e-05
## ASV1093     -1.578754e-04 -1.650638e-04 -1.725636e-04 -1.803867e-04
## ASV0994      2.081685e-04  2.177026e-04  2.276558e-04  2.380449e-04
## ASV0092     -3.449160e-04 -3.610269e-04 -3.778745e-04 -3.954911e-04
## ASV2619      7.837414e-05  8.204510e-05  8.588448e-05  8.989964e-05
## ASV0121      4.294104e-04  4.480861e-04  4.674940e-04  4.876555e-04
## ASV0932      1.507098e-04  1.578696e-04  1.653663e-04  1.732153e-04
## ASV5229      2.481722e-04  2.592682e-04  2.708266e-04  2.828637e-04
## ASV6737      2.546508e-04  2.663613e-04  2.785904e-04  2.913593e-04
## ASV11213    -3.558924e-04 -3.716136e-04 -3.879731e-04 -4.049918e-04
## ASV1151      7.392344e-04  7.729018e-04  8.080314e-04  8.446802e-04
## ASV3813      3.839941e-04  4.010742e-04  4.188583e-04  4.373705e-04
## ASV5566      8.312565e-05  8.751443e-05  9.214901e-05  9.704397e-05
## ASV7529     -3.558413e-04 -3.715579e-04 -3.879125e-04 -4.049260e-04
## ASV2193      5.192430e-04  5.433228e-04  5.684881e-04  5.947852e-04
## ASV2349      4.761618e-04  4.980088e-04  5.208207e-04  5.446367e-04
## ASV2387      4.139827e-04  4.321956e-04  4.511412e-04  4.708427e-04
## ASV2699      3.501544e-04  3.666298e-04  3.838703e-04  4.019102e-04
## ASV3353      4.524179e-04  4.728567e-04  4.941674e-04  5.163827e-04
## ASV3621      2.392515e-04  2.497423e-04  2.606520e-04  2.719935e-04
## ASV3848      4.341363e-05  4.549914e-05  4.768522e-05  4.997670e-05
## ASV4440      7.675916e-06  8.409028e-06  9.208689e-06  1.008056e-05
## ASV4751      4.787001e-04  5.006595e-04  5.235875e-04  5.475234e-04
## ASV5115      2.059201e-04  2.155123e-04  2.255399e-04  2.360215e-04
## ASV5850     -3.557520e-04 -3.714606e-04 -3.878064e-04 -4.048103e-04
## ASV6293      2.219322e-04  2.320862e-04  2.426853e-04  2.537470e-04
## ASV6513      9.975413e-05  1.047067e-04  1.099121e-04  1.153836e-04
## ASV7628     -3.557246e-04 -3.714307e-04 -3.877739e-04 -4.047750e-04
## ASV7658      2.203767e-04  2.306613e-04  2.414136e-04  2.526534e-04
## ASV0776     -4.194871e-04 -4.381836e-04 -4.576537e-04 -4.779242e-04
## ASV10227    -3.556945e-04 -3.713980e-04 -3.877383e-04 -4.047362e-04
## ASV11965    -3.556609e-04 -3.713613e-04 -3.876983e-04 -4.046927e-04
## ASV1270     -1.194172e-04 -1.245110e-04 -1.297945e-04 -1.352723e-04
## ASV13123    -2.679896e-04 -2.797148e-04 -2.919058e-04 -3.045768e-04
## ASV5828      3.555950e-04  3.712895e-04  3.876202e-04  4.046077e-04
## ASV5920     -3.555613e-04 -3.712529e-04 -3.875802e-04 -4.045641e-04
## ASV6071      3.419299e-04  3.577667e-04  3.743162e-04  3.916089e-04
## ASV6723     -1.566768e-05 -1.612491e-05 -1.657913e-05 -1.702826e-05
## ASV6727     -3.555190e-04 -3.712067e-04 -3.875299e-04 -4.045094e-04
## ASV7759     -3.554854e-04 -3.711701e-04 -3.874900e-04 -4.044659e-04
## ASV0733      2.569111e-05  2.694702e-05  2.826635e-05  2.965253e-05
## ASV1655     -5.629243e-05 -5.923326e-05 -6.233656e-05 -6.561186e-05
## ASV0755     -5.308668e-04 -5.546118e-04 -5.793493e-04 -6.051147e-04
## ASV0796      2.131725e-04  2.221586e-04  2.314706e-04  2.411157e-04
## ASV0878      4.621566e-04  4.831770e-04  5.051078e-04  5.279843e-04
## ASV4988     -2.870187e-04 -3.000963e-04 -3.137421e-04 -3.279782e-04
## ASV0083     -3.291949e-04 -3.444757e-04 -3.604444e-04 -3.771297e-04
## ASV0273      1.513047e-04  1.576688e-04  1.642647e-04  1.710979e-04
## ASV3076      1.085733e-04  1.136634e-04  1.189879e-04  1.245572e-04
## ASV1513      8.815672e-05  9.211455e-05  9.623879e-05  1.005354e-04
## ASV5159     -2.131952e-05 -2.210589e-05 -2.291013e-05 -2.373157e-05
## ASV3422     -2.191642e-04 -2.292959e-04 -2.398819e-04 -2.509411e-04
## ASV12230    -3.036870e-05 -3.160089e-05 -3.287275e-05 -3.418456e-05
## ASV1694      4.491252e-04  4.691250e-04  4.899549e-04  5.116442e-04
## ASV1249      1.982596e-04  2.073434e-04  2.168260e-04  2.267235e-04
## ASV1697     -1.087715e-04 -1.136167e-04 -1.186626e-04 -1.239162e-04
## ASV4408     -2.632617e-04 -2.743860e-04 -2.859197e-04 -2.978727e-04
## ASV0095     -3.406331e-04 -3.566445e-04 -3.733974e-04 -3.909248e-04
## ASV0410     -1.667925e-07 -4.190971e-07 -7.053149e-07 -1.028922e-06
## ASV4642     -4.231914e-04 -4.426148e-04 -4.628953e-04 -4.840677e-04
## ASV4560     -2.958025e-07 -4.486976e-08  2.414232e-07  5.667102e-07
## ASV7586     -1.996650e-04 -2.088832e-04 -2.185127e-04 -2.285706e-04
## ASV4144     -2.251491e-04 -2.356330e-04 -2.465933e-04 -2.580505e-04
## ASV0327     -2.423078e-04 -2.532672e-04 -2.646956e-04 -2.766106e-04
## ASV0946     -2.016171e-04 -2.102378e-04 -2.191846e-04 -2.284666e-04
## ASV3254     -2.636054e-04 -2.758502e-04 -2.886486e-04 -3.020242e-04
## ASV0349      3.796935e-04  3.971552e-04  4.153902e-04  4.344300e-04
## ASV0472     -2.305458e-04 -2.409792e-04 -2.518595e-04 -2.632033e-04
## ASV1330      2.299666e-04  2.399761e-04  2.503778e-04  2.611831e-04
## ASV2605      2.473559e-04  2.587333e-04  2.706146e-04  2.830202e-04
## ASV2846     -1.426909e-04 -1.495122e-04 -1.566589e-04 -1.641463e-04
## ASV3982     -1.157415e-04 -1.211945e-04 -1.269014e-04 -1.328734e-04
## ASV4116     -2.635590e-04 -2.757992e-04 -2.885926e-04 -3.019628e-04
## ASV6048     -1.545673e-04 -1.617916e-04 -1.693466e-04 -1.772467e-04
## ASV1146      3.165897e-04  3.310020e-04  3.460388e-04  3.617241e-04
## ASV13362     1.783752e-05  1.852337e-05  1.922731e-05  1.994897e-05
## ASV1422     -2.635246e-04 -2.757615e-04 -2.885513e-04 -3.019175e-04
## ASV3640     -2.634983e-04 -2.757328e-04 -2.885198e-04 -3.018831e-04
## ASV5404      2.035549e-04  2.124633e-04  2.217267e-04  2.313559e-04
## ASV6118     -2.634806e-04 -2.757133e-04 -2.884984e-04 -3.018596e-04
## ASV1115     -2.249186e-04 -2.353623e-04 -2.462768e-04 -2.576822e-04
## ASV0888     -4.797043e-04 -5.016344e-04 -5.245246e-04 -5.484132e-04
## ASV4620      5.769705e-05  5.939646e-05  6.108796e-05  6.276434e-05
## ASV3099      9.560950e-05  1.002243e-04  1.050633e-04  1.101372e-04
## ASV7099      4.452688e-05  4.669518e-05  4.897038e-05  5.135776e-05
## ASV5892     -3.022170e-04 -3.160721e-04 -3.305373e-04 -3.456370e-04
## ASV6978     -3.017871e-04 -3.157920e-04 -3.304297e-04 -3.457271e-04
## ASV6555     -1.056269e-04 -1.111322e-04 -1.169397e-04 -1.230668e-04
## ASV0539     -3.779955e-04 -3.950616e-04 -4.128552e-04 -4.314037e-04
## ASV4665      1.041636e-04  1.085158e-04  1.130219e-04  1.176850e-04
## ASV2210      2.245821e-04  2.341473e-04  2.440738e-04  2.543719e-04
## ASV1329      2.405666e-04  2.517472e-04  2.634330e-04  2.756456e-04
## ASV7123     -3.489341e-04 -3.651113e-04 -3.820184e-04 -3.996863e-04
## ASV1260      2.568242e-06  2.744617e-06  2.934026e-06  3.137455e-06
## ASV1011      3.578206e-04  3.747207e-04  3.924100e-04  4.109241e-04
## ASV4233      9.779993e-05  1.024068e-04  1.072279e-04  1.122727e-04
## ASV1475      3.600778e-04  3.763480e-04  3.933157e-04  4.110077e-04
## ASV6099     -4.169858e-04 -4.358274e-04 -4.554739e-04 -4.759552e-04
## ASV1428      7.369974e-06  8.770309e-06  1.032761e-05  1.205651e-05
## ASV5101     -4.609461e-04 -4.825064e-04 -5.050571e-04 -5.286418e-04
## ASV11827    -2.071015e-04 -2.166257e-04 -2.265719e-04 -2.369576e-04
## ASV13899    -2.354485e-04 -2.462669e-04 -2.575640e-04 -2.693592e-04
## ASV21259    -2.768399e-04 -2.896408e-04 -3.030158e-04 -3.169889e-04
## ASV6635     -1.376061e-04 -1.441226e-04 -1.509455e-04 -1.580888e-04
## ASV9922     -3.708831e-04 -3.879944e-04 -4.058693e-04 -4.245393e-04
## ASV2869      4.515559e-05  4.714348e-05  4.921075e-05  5.135977e-05
## ASV1740      2.409329e-04  2.518004e-04  2.631302e-04  2.749393e-04
## ASV4406     -3.746111e-04 -3.920775e-04 -4.103409e-04 -4.294359e-04
## ASV5586     -3.201085e-04 -3.351672e-04 -3.509249e-04 -3.674133e-04
## ASV3255     -1.260257e-04 -1.317520e-04 -1.377258e-04 -1.439569e-04
## ASV12281    -1.760863e-04 -1.839343e-04 -1.921086e-04 -2.006207e-04
## ASV5388     -3.462620e-04 -3.615202e-04 -3.773946e-04 -3.939051e-04
## ASV17660    -3.589107e-04 -3.754100e-04 -3.926404e-04 -4.106318e-04
## ASV0159      1.954201e-04  2.039671e-04  2.128584e-04  2.221057e-04
## ASV2734     -5.309079e-04 -5.550562e-04 -5.802507e-04 -6.065323e-04
## ASV2049      4.051643e-05  4.238832e-05  4.434451e-05  4.638863e-05
## ASV2465      2.349126e-05  2.410939e-05  2.471475e-05  2.530352e-05
## ASV2147      1.612996e-04  1.678717e-04  1.746618e-04  1.816729e-04
## ASV3113     -5.093925e-05 -5.320538e-05 -5.556400e-05 -5.801806e-05
## ASV0622     -3.776946e-04 -3.951406e-04 -4.133657e-04 -4.324020e-04
## ASV0437     -3.774678e-04 -3.946495e-04 -4.125763e-04 -4.312770e-04
## ASV6385     -4.138820e-04 -4.329460e-04 -4.528575e-04 -4.736514e-04
## ASV3699     -3.770904e-04 -3.947884e-04 -4.133044e-04 -4.326750e-04
## ASV2208      3.770525e-04  3.947468e-04  4.132588e-04  4.326251e-04
## ASV1053      8.560464e-05  8.950752e-05  9.358096e-05  9.783183e-05
## ASV8468     -8.337497e-05 -8.707619e-05 -9.092936e-05 -9.493959e-05
## ASV0951     -3.138517e-04 -3.280562e-04 -3.428699e-04 -3.583159e-04
## ASV0278      4.472247e-04  4.671305e-04  4.878592e-04  5.094391e-04
## ASV0914     -2.349988e-04 -2.456795e-04 -2.568214e-04 -2.684423e-04
## ASV0737      3.469276e-04  3.618518e-04  3.773475e-04  3.934303e-04
## ASV2038      5.051499e-04  5.277517e-04  5.512989e-04  5.758250e-04
## ASV2171      3.039760e-04  3.169397e-04  3.303891e-04  3.443368e-04
## ASV2607      3.468526e-04  3.617703e-04  3.772588e-04  3.933339e-04
## ASV3143      2.624054e-04  2.734869e-04  2.849734e-04  2.968744e-04
## ASV3187     -3.723812e-04 -3.884497e-04 -4.051379e-04 -4.224636e-04
## ASV3810      3.467637e-04  3.616736e-04  3.771538e-04  3.932198e-04
## ASV5060     -2.125266e-04 -2.214641e-04 -2.307251e-04 -2.403167e-04
## ASV5325      3.467143e-04  3.616200e-04  3.770955e-04  3.931566e-04
## ASV6905     -3.466824e-04 -3.615853e-04 -3.770578e-04 -3.931156e-04
## ASV7597     -3.466505e-04 -3.615506e-04 -3.770201e-04 -3.930747e-04
## ASV9652     -3.466186e-04 -3.615159e-04 -3.769824e-04 -3.930338e-04
## ASV2634      3.465867e-04  3.614813e-04  3.769448e-04  3.929928e-04
## ASV3065      3.465548e-04  3.614466e-04  3.769071e-04  3.929519e-04
## ASV3331      3.465230e-04  3.614120e-04  3.768694e-04  3.929110e-04
## ASV7434     -3.464911e-04 -3.613773e-04 -3.768318e-04 -3.928701e-04
## ASV7720      5.933662e-05  6.270693e-05  6.628295e-05  7.007781e-05
## ASV8414     -3.464627e-04 -3.613465e-04 -3.767984e-04 -3.928340e-04
## ASV12139    -3.464308e-04 -3.613119e-04 -3.767608e-04 -3.927931e-04
## ASV1824      3.374832e-04  3.519557e-04  3.669783e-04  3.825658e-04
## ASV2094      3.420168e-04  3.567018e-04  3.719466e-04  3.877666e-04
## ASV2770     -8.182199e-05 -8.601553e-05 -9.043210e-05 -9.508383e-05
## ASV3505     -1.647452e-04 -1.712636e-04 -1.779778e-04 -1.848880e-04
## ASV1935      3.463283e-04  3.612006e-04  3.766400e-04  3.926621e-04
## ASV5764     -3.462965e-04 -3.611660e-04 -3.766024e-04 -3.926213e-04
## ASV6806      2.251900e-04  2.358009e-04  2.469046e-04  2.585232e-04
## ASV6942     -3.462670e-04 -3.611339e-04 -3.765676e-04 -3.925835e-04
## ASV1166      3.810546e-04  3.975271e-04  4.146380e-04  4.324057e-04
## ASV1664      2.720260e-04  2.840457e-04  2.965534e-04  3.095650e-04
## ASV2568      3.462055e-04  3.610671e-04  3.764949e-04  3.925046e-04
## ASV3525      3.461737e-04  3.610325e-04  3.764574e-04  3.924637e-04
## ASV4965     -4.165904e-04 -4.350024e-04 -4.541644e-04 -4.741015e-04
## ASV6607     -2.122708e-04 -2.209491e-04 -2.299172e-04 -2.391789e-04
## ASV7187      1.183229e-04  1.236221e-04  1.291423e-04  1.348911e-04
## ASV0388     -3.493029e-04 -3.658086e-04 -3.830866e-04 -4.011724e-04
## ASV1420      2.868685e-06  3.130016e-06  3.414280e-06  3.723369e-06
## ASV14293     1.140344e-04  1.195635e-04  1.253637e-04  1.314483e-04
## ASV17785     2.857392e-06  3.117583e-06  3.400592e-06  3.708299e-06
## ASV7678      1.916924e-05  1.944083e-05  1.967072e-05  1.985269e-05
## ASV2253      9.615901e-05  1.008068e-04  1.056809e-04  1.107923e-04
## ASV4150      1.894174e-04  1.977023e-04  2.063173e-04  2.152729e-04
## ASV3836     -4.410321e-04 -4.610984e-04 -4.820352e-04 -5.038765e-04
## ASV16231    -3.633929e-04 -3.803257e-04 -3.980302e-04 -4.165398e-04
## ASV2730      7.326097e-06  7.667626e-06  8.025137e-06  8.399420e-06
## ASV2072      2.031090e-04  2.117708e-04  2.207574e-04  2.300770e-04
## ASV2160      5.634187e-05  5.925169e-05  6.231993e-05  6.555576e-05
## ASV5013      6.582447e-05  6.848832e-05  7.123645e-05  7.406919e-05
## ASV2586      1.201683e-04  1.255608e-04  1.311791e-04  1.370314e-04
## ASV1442      9.469305e-05  9.904665e-05  1.035908e-04  1.083328e-04
## ASV3101      1.322231e-04  1.376423e-04  1.432418e-04  1.490236e-04
## ASV3323     -1.130861e-04 -1.184011e-04 -1.239552e-04 -1.297576e-04
## ASV1812      3.412882e-04  3.559215e-04  3.711108e-04  3.868712e-04
## ASV6120     -4.171602e-05 -4.385685e-05 -4.611242e-05 -4.848915e-05
## ASV2565      7.441172e-05  7.758600e-05  8.087921e-05  8.429438e-05
## ASV6687      3.848002e-05  4.018298e-05  4.195534e-05  4.379937e-05
## ASV5357     -3.021306e-04 -3.159180e-04 -3.303062e-04 -3.453188e-04
## ASV9383      1.490901e-04  1.556133e-04  1.623963e-04  1.694474e-04
## ASV11753    -2.584787e-04 -2.702471e-04 -2.825260e-04 -2.953354e-04
## ASV11512    -7.166379e-05 -7.492358e-05 -7.832481e-05 -8.187301e-05
## ASV2791     -1.196175e-05 -1.266824e-05 -1.342012e-05 -1.422046e-05
## ASV0664     -5.460098e-04 -5.707035e-04 -5.964530e-04 -6.232980e-04
## ASV3436      5.803669e-05  6.110106e-05  6.433853e-05  6.775971e-05
## ASV5755      3.714283e-04  3.881282e-04  4.055331e-04  4.236685e-04
## ASV10970    -3.660001e-04 -3.826488e-04 -4.000180e-04 -4.181355e-04
## ASV11798    -1.867097e-04 -1.951940e-04 -2.040449e-04 -2.132762e-04
## ASV18193    -3.659487e-04 -3.825926e-04 -3.999566e-04 -4.180684e-04
## ASV2548      3.836668e-04  4.007848e-04  4.186154e-04  4.371837e-04
## ASV3901      4.147025e-04  4.332082e-04  4.524845e-04  4.725587e-04
## ASV5197      5.362489e-06  5.099137e-06  4.781095e-06  4.402760e-06
## ASV5859      1.841660e-04  1.924068e-04  2.009933e-04  2.099380e-04
## ASV6240     -3.659280e-04 -3.825699e-04 -3.999317e-04 -4.180412e-04
## ASV7281      3.658923e-04  3.825309e-04  3.998891e-04  4.179946e-04
## ASV7635      2.060411e-04  2.155341e-04  2.254488e-04  2.358025e-04
## ASV8822     -3.658637e-04 -3.824996e-04 -3.998549e-04 -4.179572e-04
## ASV4810     -7.664323e-05 -7.984074e-05 -8.314917e-05 -8.657018e-05
## ASV5308      3.829381e-04  4.003796e-04  4.185785e-04  4.375644e-04
## ASV2749     -4.198972e-04 -4.391719e-04 -4.592974e-04 -4.803079e-04
## ASV0298      3.418967e-05  3.629986e-05  3.855226e-05  4.095696e-05
## ASV2597     -3.939467e-04 -4.120942e-04 -4.310486e-04 -4.508430e-04
## ASV5758     -1.638449e-04 -1.713362e-04 -1.791561e-04 -1.873177e-04
## ASV9987     -4.158994e-04 -4.349383e-04 -4.548130e-04 -4.755568e-04
## ASV0971      8.214034e-05  8.540496e-05  8.877274e-05  9.224483e-05
## ASV0627     -4.065832e-04 -4.253532e-04 -4.449616e-04 -4.654432e-04
## ASV1758      3.674737e-04  3.842013e-04  4.016548e-04  4.198627e-04
## ASV4559      1.835260e-06  1.985346e-06  2.147296e-06  2.321947e-06
## ASV11400    -1.451197e-05 -1.497959e-05 -1.544907e-05 -1.591868e-05
## ASV11559    -3.703088e-04 -3.873686e-04 -4.051874e-04 -4.237967e-04
## ASV3943     -3.702723e-04 -3.873286e-04 -4.051436e-04 -4.237488e-04
## ASV10389     6.825957e-05  7.114294e-05  7.413032e-05  7.722376e-05
## ASV5168      3.249936e-04  3.393453e-04  3.542798e-04  3.698163e-04
## ASV5724      2.286425e-04  2.391952e-04  2.502186e-04  2.617319e-04
## ASV6337      7.034343e-05  7.318053e-05  7.610723e-05  7.912399e-05
## ASV11063     2.047056e-04  2.135261e-04  2.226853e-04  2.321927e-04
## ASV4279     -3.942968e-05 -4.122685e-05 -4.310205e-05 -4.505831e-05
## ASV7660     -1.538766e-04 -1.610804e-04 -1.686152e-04 -1.764959e-04
## ASV8218     -1.538612e-04 -1.610635e-04 -1.685967e-04 -1.764756e-04
## ASV3574      6.028867e-04  6.309349e-04  6.602563e-04  6.909055e-04
## ASV12050    -1.538641e-04 -1.610666e-04 -1.686001e-04 -1.764793e-04
## ASV3897      1.359667e-04  1.419356e-04  1.481439e-04  1.545995e-04
## ASV3856     -4.616516e-04 -4.826961e-04 -5.046548e-04 -5.275632e-04
## ASV3024     -1.475135e-04 -1.546422e-04 -1.621157e-04 -1.699504e-04
## ASV8715     -3.592058e-04 -3.756077e-04 -3.927260e-04 -4.105888e-04
## ASV6917     -1.499041e-04 -1.562152e-04 -1.627553e-04 -1.695299e-04
## ASV1132      3.732736e-04  3.906881e-04  4.088980e-04  4.279381e-04
## ASV3583      1.881301e-04  1.970065e-04  2.062976e-04  2.160223e-04
## ASV0328      5.936835e-04  6.208956e-04  6.493066e-04  6.789650e-04
## ASV0915     -1.998618e-04 -2.092309e-04 -2.190322e-04 -2.292852e-04
## ASV2677      2.026183e-04  2.122273e-04  2.222886e-04  2.328229e-04
## ASV0599      2.025014e-04  2.115258e-04  2.209263e-04  2.307166e-04
## ASV0283     -5.405867e-04 -5.651786e-04 -5.908364e-04 -6.176017e-04
## ASV1028      2.249815e-04  2.355137e-04  2.465296e-04  2.580506e-04
## ASV0523      4.088525e-04  4.277622e-04  4.475194e-04  4.681594e-04
## ASV8201     -2.492721e-04 -2.608324e-04 -2.729127e-04 -2.855349e-04
## ASV2795     -7.785153e-05 -8.136728e-05 -8.503318e-05 -8.885490e-05
## ASV3563     -7.772688e-05 -8.123666e-05 -8.489631e-05 -8.871147e-05
## ASV1553     -1.404353e-04 -1.464374e-04 -1.526660e-04 -1.591271e-04
## ASV7155     -4.169495e-05 -4.410438e-05 -4.666033e-05 -4.937168e-05
## ASV0365      5.209339e-04  5.444591e-04  5.689894e-04  5.945629e-04
## ASV8583     -3.581666e-04 -3.743499e-04 -3.912240e-04 -4.088149e-04
## ASV5400      1.931284e-05  2.025435e-05  2.124125e-05  2.227555e-05
## ASV5908      2.756075e-04  2.876976e-04  3.002705e-04  3.133411e-04
## ASV2075      1.575511e-04  1.648573e-04  1.724924e-04  1.804701e-04
## ASV2520     -3.143471e-04 -3.289480e-04 -3.442094e-04 -3.601599e-04
## ASV9596     -1.528127e-04 -1.594572e-04 -1.663623e-04 -1.735357e-04
## ASV1131     -5.007862e-05 -5.200649e-05 -5.398845e-05 -5.602429e-05
## ASV0579     -1.017355e-04 -1.063264e-04 -1.111135e-04 -1.161041e-04
## ASV0288     -4.973931e-04 -5.197492e-04 -5.430502e-04 -5.673308e-04
## ASV4053      8.019513e-05  8.333017e-05  8.655600e-05  8.987233e-05
## ASV1736     -2.662313e-04 -2.783489e-04 -2.909917e-04 -3.041799e-04
## ASV1254      2.725549e-04  2.845616e-04  2.970541e-04  3.100485e-04
## ASV9038     -4.364611e-04 -4.565188e-04 -4.774628e-04 -4.993289e-04
## ASV4746      3.992651e-04  4.178874e-04  4.373600e-04  4.577201e-04
## ASV5803      1.509845e-04  1.579187e-04  1.651595e-04  1.727194e-04
## ASV0525      1.751176e-05  1.836153e-05  1.925302e-05  2.018828e-05
## ASV1974      2.280235e-04  2.379664e-04  2.483006e-04  2.590377e-04
## ASV1827      3.832936e-04  4.003179e-04  4.180428e-04  4.364923e-04
## ASV30780     1.821973e-05  1.887675e-05  1.954604e-05  2.022657e-05
## ASV9342      1.501305e-05  1.589854e-05  1.684149e-05  1.784595e-05
## ASV21626    -3.636571e-04 -3.801231e-04 -3.972946e-04 -4.151982e-04
## ASV1232     -2.568028e-04 -2.683161e-04 -2.803130e-04 -2.928110e-04
## ASV5578     -2.604211e-04 -2.723705e-04 -2.848470e-04 -2.978718e-04
## ASV5868      2.712950e-04  2.831855e-04  2.955522e-04  3.084104e-04
## ASV13625    -1.127250e-04 -1.177555e-04 -1.229946e-04 -1.284495e-04
## ASV3614      4.109399e-05  4.273899e-05  4.443534e-05  4.618330e-05
## ASV2128      2.357264e-04  2.466520e-04  2.580690e-04  2.699983e-04
## ASV5086      5.106894e-05  5.331414e-05  5.564905e-05  5.807644e-05
## ASV6614     -2.604068e-04 -2.723548e-04 -2.848298e-04 -2.978529e-04
## ASV9451     -2.603812e-04 -2.723268e-04 -2.847991e-04 -2.978194e-04
## ASV9533     -2.603555e-04 -2.722988e-04 -2.847685e-04 -2.977859e-04
## ASV10697     3.966554e-06  4.334292e-06  4.735231e-06  5.172244e-06
## ASV1473     -1.207687e-04 -1.259692e-04 -1.313685e-04 -1.369720e-04
## ASV1414     -7.753455e-05 -8.116569e-05 -8.496193e-05 -8.893016e-05
## ASV1567     -7.698320e-05 -8.084480e-05 -8.490750e-05 -8.918230e-05
## ASV6395     -2.630338e-04 -2.752322e-04 -2.879810e-04 -3.013036e-04
## ASV2366      1.035416e-04  1.077676e-04  1.121323e-04  1.166371e-04
## ASV2537      1.036678e-04  1.080013e-04  1.124884e-04  1.171322e-04
## ASV5378     -2.630208e-04 -2.752177e-04 -2.879650e-04 -3.012859e-04
## ASV5929     -2.767677e-04 -2.895889e-04 -3.029874e-04 -3.169874e-04
## ASV6360      2.178532e-04  2.274718e-04  2.374797e-04  2.478891e-04
## ASV7916     -4.540893e-05 -4.772909e-05 -5.017420e-05 -5.275148e-05
## ASV13322     8.793088e-05  9.216736e-05  9.660926e-05  1.012666e-04
## ASV6207     -3.318550e-04 -3.469960e-04 -3.627966e-04 -3.792828e-04
## ASV8823     -2.644342e-04 -2.765805e-04 -2.892634e-04 -3.025047e-04
## ASV1379      3.677383e-04  3.845513e-04  4.021000e-04  4.204136e-04
## ASV3259     -3.677023e-04 -3.845119e-04 -4.020569e-04 -4.203665e-04
## ASV18748     1.737997e-06  2.005727e-06  2.302977e-06  2.632610e-06
## ASV3570      8.011996e-05  8.383016e-05  8.770698e-05  9.175741e-05
## ASV0790     -7.632487e-05 -7.897815e-05 -8.167496e-05 -8.441102e-05
## ASV5149     -3.354564e-04 -3.506372e-04 -3.664678e-04 -3.829726e-04
## ASV1730     -3.465074e-04 -3.622637e-04 -3.787014e-04 -3.958469e-04
## ASV3488     -2.802737e-05 -2.919918e-05 -3.041272e-05 -3.166885e-05
## ASV5486     -3.777626e-04 -3.955284e-04 -4.141193e-04 -4.335725e-04
## ASV1319      5.614022e-05  5.785514e-05  5.957104e-05  6.128182e-05
## ASV15328    -2.584118e-04 -2.701773e-04 -2.824535e-04 -2.952604e-04
## ASV5994      3.733398e-04  3.903926e-04  4.081903e-04  4.267621e-04
## ASV4992     -2.958072e-05 -3.082808e-05 -3.212041e-05 -3.345863e-05
## ASV1788     -4.053406e-04 -4.231204e-04 -4.416126e-04 -4.608398e-04
## ASV3264     -3.763820e-06 -3.672628e-06 -3.553189e-06 -3.402162e-06
## ASV4895      1.711959e-05  1.778171e-05  1.846173e-05  1.915935e-05
## ASV9218     -5.529190e-06 -5.503550e-06 -5.451237e-06 -5.368869e-06
## ASV0736     -8.816889e-06 -9.477459e-06 -1.019050e-05 -1.096024e-05
## ASV0916      2.583514e-04  2.701115e-04  2.823819e-04  2.951824e-04
## ASV15761    -2.583262e-04 -2.700839e-04 -2.823517e-04 -2.951495e-04
## ASV4191      3.207945e-04  3.350708e-04  3.499368e-04  3.654130e-04
## ASV3268     -6.525393e-05 -6.800403e-05 -7.085286e-05 -7.380236e-05
## ASV15321    -4.295147e-05 -4.514903e-05 -4.746454e-05 -4.990468e-05
## ASV0708     -2.590240e-04 -2.710754e-04 -2.836740e-04 -2.968434e-04
## ASV4100      2.971760e-05  3.086334e-05  3.203991e-05  3.324681e-05
## ASV1627      2.049288e-04  2.135431e-04  2.224709e-04  2.317194e-04
## ASV7045     -2.288281e-04 -2.393157e-04 -2.502637e-04 -2.616905e-04
## ASV3271      5.248719e-05  5.422892e-05  5.599325e-05  5.777708e-05
## ASV6200     -4.015904e-05 -4.209439e-05 -4.412440e-05 -4.625385e-05
## ASV2727     -2.717148e-04 -2.846114e-04 -2.981144e-04 -3.122514e-04
## ASV3523     -3.570274e-04 -3.731959e-04 -3.900576e-04 -4.076385e-04
## ASV2259      2.412335e-04  2.522392e-04  2.637250e-04  2.757097e-04
## ASV0181      3.536988e-04  3.696074e-04  3.861888e-04  4.034677e-04
## ASV1680      7.096790e-04  7.419226e-04  7.755589e-04  8.106416e-04
## ASV0176      7.149503e-05  7.454075e-05  7.769893e-05  8.097207e-05
## ASV10458    -2.595685e-04 -2.714404e-04 -2.838325e-04 -2.967656e-04
## ASV10658    -2.595431e-04 -2.714125e-04 -2.838020e-04 -2.967323e-04
## ASV16807    -2.595176e-04 -2.713847e-04 -2.837716e-04 -2.966991e-04
## ASV2113     -2.594922e-04 -2.713569e-04 -2.837412e-04 -2.966658e-04
## ASV2403      2.654362e-04  2.773730e-04  2.898140e-04  3.027774e-04
## ASV2484     -2.594816e-04 -2.713452e-04 -2.837284e-04 -2.966518e-04
## ASV8876     -2.594561e-04 -2.713174e-04 -2.836980e-04 -2.966186e-04
## ASV0386      3.805451e-04  3.982275e-04  4.167104e-04  4.360283e-04
## ASV0351      1.040184e-04  1.085765e-04  1.133156e-04  1.182413e-04
## ASV4942     -1.476889e-04 -1.543962e-04 -1.613937e-04 -1.686929e-04
## ASV5128     -1.148598e-04 -1.201934e-04 -1.257676e-04 -1.315925e-04
## ASV3496      1.299762e-04  1.363173e-04  1.429731e-04  1.499598e-04
## ASV3329      3.786147e-04  3.961494e-04  4.144722e-04  4.336164e-04
## ASV7878     -2.583872e-04 -2.701450e-04 -2.824121e-04 -2.952083e-04
## ASV8251     -9.814334e-05 -1.026046e-04 -1.072584e-04 -1.121119e-04
## ASV15958    -8.507051e-05 -8.900960e-05 -9.312539e-05 -9.742527e-05
## ASV7972     -3.700818e-04 -3.871142e-04 -4.049023e-04 -4.234772e-04
## ASV2088      3.700453e-04  3.870742e-04  4.048586e-04  4.234294e-04
## ASV3054     -1.741925e-04 -1.822112e-04 -1.905854e-04 -1.993296e-04
## ASV4494     -3.699942e-04 -3.870183e-04 -4.047975e-04 -4.233625e-04
## ASV0087     -6.998044e-04 -7.315834e-04 -7.647336e-04 -7.993077e-04
## ASV1614     -2.860171e-04 -2.989795e-04 -3.124983e-04 -3.265947e-04
## ASV3037     -1.586314e-04 -1.658731e-04 -1.734308e-04 -1.813170e-04
## ASV6615     -4.241608e-05 -4.458668e-05 -4.687327e-05 -4.928232e-05
## ASV1027      1.070881e-04  1.118650e-04  1.168397e-04  1.220191e-04
## ASV2754     -6.802665e-05 -7.139566e-05 -7.493572e-05 -7.865574e-05
## ASV0536     -5.290435e-05 -5.546267e-05 -5.814568e-05 -6.095948e-05
## ASV2318     -1.115488e-04 -1.167984e-04 -1.222921e-04 -1.280408e-04
## ASV5954      2.187387e-04  2.282565e-04  2.381483e-04  2.484254e-04
## ASV9028      1.553311e-04  1.624603e-04  1.699038e-04  1.776743e-04
## ASV6600     -2.631580e-04 -2.753650e-04 -2.881229e-04 -3.014550e-04
## ASV1923     -6.876866e-05 -7.180982e-05 -7.497413e-05 -7.826550e-05
## ASV4034     -5.206179e-05 -5.480540e-05 -5.770234e-05 -6.076172e-05
## ASV9933     -2.631214e-04 -2.753250e-04 -2.880790e-04 -3.014070e-04
## ASV1575      4.853680e-05  5.057231e-05  5.268166e-05  5.486663e-05
## ASV7812     -4.459233e-04 -4.662279e-04 -4.874133e-04 -5.095136e-04
## ASV0515      2.858137e-04  2.984663e-04  3.116350e-04  3.253370e-04
## ASV1149     -3.430869e-05 -3.636279e-05 -3.854977e-05 -4.087860e-05
## ASV3791      1.206720e-04  1.263726e-04  1.323399e-04  1.385861e-04
## ASV4065     -4.172224e-04 -4.362622e-04 -4.561311e-04 -4.768618e-04
## ASV10631    -2.444915e-05 -2.580030e-05 -2.723260e-05 -2.875133e-05
## ASV2359     -4.094052e-04 -4.272414e-04 -4.457816e-04 -4.650476e-04
## ASV3206     -2.598166e-04 -2.717153e-04 -2.841373e-04 -2.971036e-04
## ASV4415      2.114809e-04  2.211611e-04  2.312655e-04  2.418109e-04
## ASV4467     -1.858257e-04 -1.942217e-04 -2.029763e-04 -2.121030e-04
## ASV5598      3.201220e-04  3.352206e-04  3.510241e-04  3.675647e-04
## ASV5910     -2.867379e-04 -2.998970e-04 -3.136373e-04 -3.279823e-04
## ASV9494     -2.597471e-04 -2.716393e-04 -2.840542e-04 -2.970127e-04
## ASV6548     -2.119692e-04 -2.216304e-04 -2.317121e-04 -2.422311e-04
## ASV8669     -2.597012e-04 -2.715891e-04 -2.839993e-04 -2.969527e-04
## ASV0674      1.601929e-04  1.671692e-04  1.744188e-04  1.819496e-04
## ASV0061     -8.100645e-05 -8.559345e-05 -9.045845e-05 -9.561897e-05
## ASV0310     -1.597146e-04 -1.667637e-04 -1.741032e-04 -1.817436e-04
## ASV0582      4.846855e-05  5.038734e-05  5.236419e-05  5.439920e-05
## ASV0739      4.931443e-04  5.160078e-04  5.399005e-04  5.648657e-04
## ASV1557      2.067165e-04  2.165192e-04  2.267836e-04  2.375312e-04
## ASV0146      4.563059e-04  4.763000e-04  4.970923e-04  5.187078e-04
## ASV3832      4.673766e-04  4.882441e-04  5.099791e-04  5.326119e-04
## ASV0734      1.053377e-04  1.102595e-04  1.154053e-04  1.207848e-04
## ASV3036     -3.447524e-04 -3.607645e-04 -3.775013e-04 -3.949940e-04
## ASV0240      9.204842e-05  9.615168e-05  1.004250e-04  1.048741e-04
## ASV2513     -5.148040e-04 -5.379866e-04 -5.621521e-04 -5.873366e-04
## ASV1118     -1.383217e-04 -1.448885e-04 -1.517636e-04 -1.589609e-04
## ASV7286     -2.588905e-04 -2.706987e-04 -2.830213e-04 -2.958785e-04
## ASV1077      3.447110e-04  3.601217e-04  3.761761e-04  3.928969e-04
## ASV1255     -2.588362e-04 -2.706394e-04 -2.829566e-04 -2.958079e-04
## ASV1794     -1.585729e-05 -1.662636e-05 -1.743293e-05 -1.827882e-05
## ASV2439     -2.588120e-04 -2.706130e-04 -2.829277e-04 -2.957763e-04
## ASV2467     -2.587867e-04 -2.705853e-04 -2.828974e-04 -2.957432e-04
## ASV3346     -2.587614e-04 -2.705577e-04 -2.828672e-04 -2.957102e-04
## ASV3973     -2.587361e-04 -2.705300e-04 -2.828370e-04 -2.956772e-04
## ASV4521      1.138641e-04  1.189259e-04  1.241953e-04  1.296791e-04
## ASV1909     -3.089920e-04 -3.234656e-04 -3.386051e-04 -3.544399e-04
## ASV3855     -2.315396e-04 -2.419895e-04 -2.528842e-04 -2.642403e-04
## ASV0810      3.098697e-04  3.241050e-04  3.389696e-04  3.544887e-04
## ASV1765      3.701177e-04  3.872892e-04  4.052358e-04  4.239905e-04
## ASV0763      2.005779e-04  2.097039e-04  2.192253e-04  2.291576e-04
## ASV0302     -2.181526e-04 -2.279196e-04 -2.380950e-04 -2.486935e-04
## ASV2643     -2.958627e-04 -3.087721e-04 -3.221948e-04 -3.361473e-04
## ASV0440      1.161358e-04  1.215781e-04  1.272692e-04  1.332198e-04
## ASV4899     -2.083163e-04 -2.174221e-04 -2.268882e-04 -2.367253e-04
## ASV0287     -1.277662e-04 -1.336896e-04 -1.398808e-04 -1.463513e-04
## ASV3220      1.600306e-04  1.674876e-04  1.752828e-04  1.834305e-04
## ASV1007     -9.093122e-05 -9.486246e-05 -9.894497e-05 -1.031829e-04
## ASV2929     -5.757614e-05 -5.994233e-05 -6.238815e-05 -6.491464e-05
## ASV1496     -2.206416e-04 -2.309657e-04 -2.417638e-04 -2.530568e-04
## ASV4975      9.619271e-05  1.006259e-04  1.052555e-04  1.100892e-04
## ASV4392     -1.228506e-05 -1.256162e-05 -1.282321e-05 -1.306668e-05
## ASV4653     -2.622475e-04 -2.743698e-04 -2.870352e-04 -3.002666e-04
## ASV0230     -1.345726e-04 -1.408782e-04 -1.474738e-04 -1.543720e-04
## ASV0840      1.891271e-04  1.978497e-04  2.069614e-04  2.164785e-04
## ASV4132     -5.691821e-05 -5.965912e-05 -6.253281e-05 -6.554571e-05
## ASV3344      1.959009e-04  2.046119e-04  2.136821e-04  2.231240e-04
## ASV12096    -2.661294e-04 -2.784730e-04 -2.913719e-04 -3.048492e-04
## ASV1550      8.703802e-05  9.059900e-05  9.427872e-05  9.807867e-05
## ASV3542     -3.951888e-04 -4.136776e-04 -4.330117e-04 -4.532273e-04
## ASV8795     -1.527733e-04 -1.598688e-04 -1.672848e-04 -1.750350e-04
## ASV2532     -8.545113e-06 -9.026684e-06 -9.537662e-06 -1.007997e-05
## ASV3087      6.256004e-05  6.527749e-05  6.810103e-05  7.103375e-05
## ASV9476     -1.527625e-04 -1.598569e-04 -1.672717e-04 -1.750206e-04
## ASV13721    -1.527472e-04 -1.598402e-04 -1.672535e-04 -1.750006e-04
## ASV3842      2.496545e-04  2.607182e-04  2.722343e-04  2.842182e-04
## ASV1663      4.494363e-04  4.693741e-04  4.901298e-04  5.117311e-04
## ASV0432      1.056163e-04  1.102920e-04  1.151586e-04  1.202223e-04
## ASV4356      4.465398e-04  4.668611e-04  4.880634e-04  5.101811e-04
## ASV4524      1.095024e-04  1.147296e-04  1.202060e-04  1.259433e-04
## ASV0169     -2.215437e-04 -2.319250e-04 -2.427836e-04 -2.541405e-04
## ASV0368     -1.903881e-04 -1.992989e-04 -2.086182e-04 -2.183640e-04
## ASV2603      8.092536e-08  8.081551e-08  7.962100e-08  7.709809e-08
## ASV3777      2.502708e-04  2.617471e-04  2.737287e-04  2.862357e-04
## ASV3978      2.167177e-04  2.264955e-04  2.366886e-04  2.473122e-04
## ASV0413     -1.796279e-04 -1.880279e-04 -1.968123e-04 -2.059979e-04
## ASV0997     -3.957536e-08 -3.558674e-08 -3.015765e-08 -2.301290e-08
## ASV1195     -3.958160e-08 -3.559610e-08 -3.017100e-08 -2.303130e-08
## ASV2522     -1.176749e-04 -1.230366e-04 -1.286314e-04 -1.344683e-04
## ASV4733      2.152645e-04  2.251649e-04  2.355035e-04  2.462979e-04
## ASV1063      3.790450e-04  3.969244e-04  4.156383e-04  4.352247e-04
## ASV0612     -4.822489e-04 -5.047054e-04 -5.281843e-04 -5.527300e-04
## ASV1903     -3.789618e-04 -3.968332e-04 -4.155384e-04 -4.351152e-04
## ASV3576     -1.114140e-04 -1.169466e-04 -1.227625e-04 -1.288766e-04
## ASV4285     -2.695634e-04 -2.821323e-04 -2.952734e-04 -3.090111e-04
## ASV3406     -1.399247e-04 -1.463773e-04 -1.531177e-04 -1.601579e-04
## ASV2379     -2.571257e-04 -2.681941e-04 -2.796877e-04 -2.916184e-04
## ASV0528      3.286281e-04  3.437785e-04  3.596029e-04  3.761289e-04
## ASV6190     -4.312793e-05 -4.523315e-05 -4.744262e-05 -4.976156e-05
## ASV1537     -2.877462e-06 -2.860944e-06 -2.829398e-06 -2.780830e-06
## ASV16780    -2.916215e-04 -3.048795e-04 -3.187114e-04 -3.331394e-04
## ASV0477      7.250907e-04  7.583057e-04  7.929808e-04  8.291745e-04
## ASV1499      1.681712e-04  1.764525e-04  1.851492e-04  1.942824e-04
## ASV14736     1.255483e-04  1.312249e-04  1.371448e-04  1.433172e-04
## ASV0179     -1.048338e-04 -1.097027e-04 -1.147917e-04 -1.201101e-04
## ASV3153      1.020440e-05  1.104824e-05  1.196429e-05  1.295870e-05
## ASV0266      3.394128e-04  3.551162e-04  3.715253e-04  3.886700e-04
## ASV0761      5.006239e-04  5.232585e-04  5.468621e-04  5.714712e-04
## ASV0269     -5.050925e-05 -5.316395e-05 -5.596752e-05 -5.892899e-05
## ASV7259     -9.653645e-05 -1.013559e-04 -1.064217e-04 -1.117466e-04
## ASV2067     -1.055796e-04 -1.102220e-04 -1.150511e-04 -1.200730e-04
## ASV2985     -2.976327e-04 -3.112698e-04 -3.255043e-04 -3.403596e-04
## ASV0975     -4.518953e-04 -4.727921e-04 -4.946253e-04 -5.174342e-04
## ASV2240      2.669534e-04  2.787967e-04  2.911270e-04  3.039611e-04
## ASV2297      8.577590e-05  8.930181e-05  9.294742e-05  9.671457e-05
## ASV2657      1.120004e-04  1.168872e-04  1.219679e-04  1.272487e-04
## ASV3784      4.835676e-06  5.279361e-06  5.762400e-06  6.288096e-06
## ASV4333      4.834763e-06  5.278319e-06  5.761212e-06  6.286741e-06
## ASV5547      2.292702e-04  2.391271e-04  2.493620e-04  2.599855e-04
## ASV5813      9.315907e-05  9.719392e-05  1.013854e-04  1.057381e-04
## ASV8049      1.122942e-04  1.173281e-04  1.225738e-04  1.280392e-04
## ASV8661     -4.848262e-06 -5.293000e-06 -5.777172e-06 -6.304086e-06
## ASV9510      1.310927e-04  1.369337e-04  1.430166e-04  1.493498e-04
## ASV1401      6.869954e-05  7.172989e-05  7.488334e-05  7.816401e-05
## ASV1417     -1.355573e-04 -1.411034e-04 -1.468354e-04 -1.527560e-04
## ASV2169      4.800787e-04  5.019489e-04  5.247702e-04  5.485801e-04
## ASV5354     -4.865351e-06 -5.311672e-06 -5.797569e-06 -6.326362e-06
## ASV5379     -4.864433e-06 -5.310624e-06 -5.796374e-06 -6.324999e-06
## ASV6078     -4.863515e-06 -5.309577e-06 -5.795180e-06 -6.323638e-06
## ASV6417      2.926353e-04  3.057391e-04  3.193917e-04  3.336127e-04
## ASV8304      2.113639e-04  2.206325e-04  2.302720e-04  2.402941e-04
## ASV8766     -4.892661e-06 -5.341331e-06 -5.829764e-06 -6.361293e-06
## ASV10861     8.804018e-05  9.183770e-05  9.578084e-05  9.987357e-05
## ASV2057      4.748542e-04  4.965162e-04  5.191221e-04  5.427091e-04
## ASV4499      1.647067e-04  1.717244e-04  1.790036e-04  1.865507e-04
## ASV7415      5.278510e-05  5.522638e-05  5.777595e-05  6.043808e-05
## ASV2475     -2.038415e-04 -2.132085e-04 -2.229905e-04 -2.332044e-04
## ASV3517     -3.346083e-04 -3.502760e-04 -3.666646e-04 -3.838060e-04
## ASV1864      2.225635e-04  2.324794e-04  2.428055e-04  2.535560e-04
## ASV2756      2.578726e-04  2.695873e-04  2.818080e-04  2.945543e-04
## ASV0778      2.578475e-04  2.695598e-04  2.817780e-04  2.945216e-04
## ASV3201      6.031026e-05  6.344564e-05  6.675333e-05  7.024342e-05
## ASV3358      2.578264e-04  2.695368e-04  2.817529e-04  2.944942e-04
## ASV5681     -2.578013e-04 -2.695093e-04 -2.817229e-04 -2.944614e-04
## ASV7256      1.252930e-04  1.310915e-04  1.371526e-04  1.434878e-04
## ASV1704     -2.632062e-04 -2.750585e-04 -2.874122e-04 -3.002854e-04
## ASV4445      4.115766e-04  4.294562e-04  4.480369e-04  4.673399e-04
## ASV8649     -2.577502e-04 -2.694536e-04 -2.816621e-04 -2.943951e-04
## ASV0597      2.678628e-04  2.800164e-04  2.926936e-04  3.059146e-04
## ASV0861      3.404376e-04  3.557230e-04  3.716524e-04  3.882491e-04
## ASV2423      4.133261e-04  4.319676e-04  4.514008e-04  4.716550e-04
## ASV1548      1.997214e-04  2.082531e-04  2.171046e-04  2.262839e-04
## ASV2564      3.432388e-04  3.585195e-04  3.744305e-04  3.909933e-04
## ASV2999      5.706002e-04  5.959111e-04  6.222601e-04  6.496821e-04
## ASV4543     -2.077580e-04 -2.174805e-04 -2.276501e-04 -2.382866e-04
## ASV8452      1.953454e-04  2.038712e-04  2.127335e-04  2.219424e-04
## ASV17287    -4.239615e-05 -4.460209e-05 -4.692978e-05 -4.938644e-05
## ASV3503     -2.659713e-04 -2.784466e-04 -2.914979e-04 -3.051511e-04
## ASV4727     -4.684038e-05 -4.933564e-05 -5.197296e-05 -5.476100e-05
## ASV5995     -2.262096e-04 -2.367999e-04 -2.478775e-04 -2.594639e-04
## ASV1665     -7.242006e-05 -7.580441e-05 -7.934368e-05 -8.304466e-05
## ASV2690     -3.372567e-04 -3.527098e-04 -3.688429e-04 -3.856835e-04
## ASV2823     -2.714881e-05 -2.832125e-05 -2.953910e-05 -3.080370e-05
## ASV5241     -4.509341e-04 -4.715854e-04 -4.931430e-04 -5.156431e-04
## ASV5473     -1.303529e-04 -1.365330e-04 -1.430044e-04 -1.497805e-04
## ASV2785      5.906653e-05  6.192417e-05  6.492119e-05  6.806438e-05
## ASV6645     -1.901967e-04 -1.988165e-04 -2.078064e-04 -2.171803e-04
## ASV0562      7.587543e-05  7.904491e-05  8.232463e-05  8.571627e-05
## ASV1163      7.813550e-05  8.178240e-05  8.559529e-05  8.958124e-05
## ASV1825      1.462643e-04  1.527799e-04  1.595642e-04  1.666265e-04
## ASV3795      3.238064e-04  3.384520e-04  3.537251e-04  3.696497e-04
## ASV3869     -7.364623e-05 -7.724470e-05 -8.102251e-05 -8.498887e-05
## ASV4330      2.499393e-04  2.613226e-04  2.731999e-04  2.855906e-04
## ASV6754      9.499719e-05  9.931931e-05  1.038284e-04  1.085315e-04
## ASV4598     -3.093533e-06 -3.386439e-06 -3.706577e-06 -4.056405e-06
## ASV2100      1.908824e-04  1.992947e-04  2.080474e-04  2.171515e-04
## ASV3518      9.482390e-05  9.898566e-05  1.033131e-04  1.078112e-04
## ASV3823      3.943376e-04  4.120559e-04  4.305220e-04  4.497630e-04
## ASV7357      2.423939e-04  2.533779e-04  2.648339e-04  2.767798e-04
## ASV7403     -3.095090e-04 -3.234604e-04 -3.380043e-04 -3.531625e-04
## ASV2934     -1.282452e-05 -1.329102e-05 -1.376673e-05 -1.425096e-05
## ASV5277     -1.611021e-04 -1.683578e-04 -1.759206e-04 -1.838018e-04
## ASV0281     -4.750687e-04 -4.965809e-04 -5.190170e-04 -5.424122e-04
## ASV11181    -1.783215e-04 -1.868423e-04 -1.957717e-04 -2.051294e-04
## ASV0254     -5.951516e-05 -6.164157e-05 -6.380603e-05 -6.600497e-05
## ASV0201     -8.331043e-05 -8.740172e-05 -9.169894e-05 -9.621285e-05
## ASV3656     -2.060618e-04 -2.160124e-04 -2.264483e-04 -2.373936e-04
## ASV7994     -3.677930e-04 -3.846340e-04 -4.022150e-04 -4.205654e-04
## ASV3584     -1.170642e-04 -1.218202e-04 -1.267339e-04 -1.318074e-04
## ASV2157      3.763239e-04  3.930825e-04  4.105361e-04  4.287089e-04
## ASV2935     -4.869591e-05 -5.093505e-05 -5.327334e-05 -5.571482e-05
## ASV9024     -3.432517e-04 -3.586518e-04 -3.746994e-04 -3.914179e-04
## ASV7711      2.072180e-04  2.169769e-04  2.271900e-04  2.378776e-04
## ASV11330    -2.614025e-04 -2.734478e-04 -2.860294e-04 -2.991697e-04
## ASV1875      2.300037e-04  2.405176e-04  2.514929e-04  2.629484e-04
## ASV5861      1.732926e-04  1.814591e-04  1.900054e-04  1.989488e-04
## ASV11562     1.524131e-05  1.597573e-05  1.674537e-05  1.755187e-05
## ASV18559    -2.613941e-04 -2.734386e-04 -2.860194e-04 -2.991587e-04
## ASV4384      2.539290e-04  2.658644e-04  2.783528e-04  2.914189e-04
## ASV1302      5.118487e-04  5.343022e-04  5.576580e-04  5.819454e-04
## ASV4673     -3.438398e-04 -3.598098e-04 -3.765010e-04 -3.939439e-04
## ASV1956      5.629923e-05  5.857870e-05  6.093504e-05  6.336974e-05
## ASV3286      2.403225e-04  2.516285e-04  2.634587e-04  2.758366e-04
## ASV4866     -3.767292e-04 -3.943971e-04 -4.128810e-04 -4.322172e-04
## ASV3129     -1.845960e-04 -1.931822e-04 -2.021586e-04 -2.115421e-04
## ASV4104      4.229191e-04  4.422055e-04  4.623315e-04  4.833302e-04
## ASV8983      3.449534e-06  3.607582e-06  3.773195e-06  3.946821e-06
## ASV2201      1.604767e-04  1.674513e-04  1.746987e-04  1.822269e-04
## ASV3055      1.090440e-04  1.135742e-04  1.182630e-04  1.231134e-04
## ASV0534     -5.502268e-04 -5.750530e-04 -6.009349e-04 -6.279117e-04
## ASV1019      1.938814e-05  2.051603e-05  2.171566e-05  2.299194e-05
## ASV18482    -2.559047e-04 -2.674349e-04 -2.794543e-04 -2.919810e-04
## ASV2694      8.429048e-05  8.780032e-05  9.143361e-05  9.519268e-05
## ASV3412     -7.792997e-05 -8.123975e-05 -8.467088e-05 -8.822598e-05
## ASV4174     -2.558740e-04 -2.674014e-04 -2.794178e-04 -2.919411e-04
## ASV4281     -2.558492e-04 -2.673744e-04 -2.793883e-04 -2.919089e-04
## ASV4949      2.862277e-04  2.988902e-04  3.120695e-04  3.257828e-04
## ASV5881      1.347783e-04  1.408150e-04  1.471043e-04  1.536552e-04
## ASV6299     -1.129532e-04 -1.179016e-04 -1.230468e-04 -1.283948e-04
## ASV0676      2.933313e-04  3.064387e-04  3.200935e-04  3.343153e-04
## ASV1066     -1.998426e-04 -2.087021e-04 -2.179238e-04 -2.275195e-04
## ASV1300     -1.711906e-04 -1.788519e-04 -1.868331e-04 -1.951454e-04
## ASV6455      8.383905e-05  8.767528e-05  9.167989e-05  9.585964e-05
## ASV3455     -2.558420e-04 -2.673665e-04 -2.793797e-04 -2.918996e-04
## ASV6531     -2.558173e-04 -2.673395e-04 -2.793502e-04 -2.918674e-04
## ASV0490      5.102087e-04  5.328424e-04  5.564099e-04  5.809441e-04
## ASV2588      2.975259e-05  3.160472e-05  3.358223e-05  3.569402e-05
## ASV5364      1.609630e-04  1.681702e-04  1.756786e-04  1.834987e-04
## ASV0981     -3.590989e-04 -3.757601e-04 -3.931731e-04 -4.113699e-04
## ASV1563     -7.377148e-05 -7.720513e-05 -8.079530e-05 -8.454886e-05
## ASV0376     -3.445136e-04 -3.604895e-04 -3.771848e-04 -3.946299e-04
## ASV7308     -2.287623e-06 -2.509207e-06 -2.752125e-06 -3.018409e-06
## ASV4817      5.410291e-05  5.630925e-05  5.858767e-05  6.093880e-05
## ASV8716     -3.596143e-04 -3.749105e-04 -3.907794e-04 -4.072362e-04
## ASV1849      4.598239e-04  4.797354e-04  5.004198e-04  5.218994e-04
## ASV9423     -3.575489e-04 -3.736054e-04 -3.903394e-04 -4.077754e-04
## ASV7690      1.370854e-05  1.438478e-05  1.509447e-05  1.583919e-05
## ASV4901      1.983897e-04  2.075409e-04  2.170999e-04  2.270835e-04
## ASV1830     -6.529053e-05 -6.882267e-05 -7.255949e-05 -7.651361e-05
## ASV2316     -2.636308e-04 -2.748914e-04 -2.865805e-04 -2.987102e-04
## ASV0693      3.972760e-04  4.155134e-04  4.345555e-04  4.544350e-04
## ASV1243     -2.070343e-05 -2.133188e-05 -2.195919e-05 -2.258279e-05
## ASV3867      1.049777e-04  1.098942e-04  1.150365e-04  1.204144e-04
## ASV7932      2.251567e-04  2.354698e-04  2.462354e-04  2.574716e-04
## ASV12608     1.641138e-04  1.719725e-04  1.802084e-04  1.888397e-04
## ASV1661      2.353295e-04  2.459938e-04  2.571159e-04  2.687131e-04
## ASV3957      2.482694e-04  2.597355e-04  2.717151e-04  2.842297e-04
## ASV0830     -3.900718e-04 -4.077122e-04 -4.261079e-04 -4.452877e-04
## ASV2078      4.437601e-04  4.640199e-04  4.851657e-04  5.072329e-04
## ASV13932    -2.624099e-04 -2.745491e-04 -2.872332e-04 -3.004851e-04
## ASV5300     -2.623839e-04 -2.745206e-04 -2.872020e-04 -3.004510e-04
## ASV1014     -1.404515e-04 -1.467923e-04 -1.534027e-04 -1.602925e-04
## ASV13059    -8.263087e-05 -8.682107e-05 -9.123164e-05 -9.587455e-05
## ASV4340      5.285861e-05  5.517507e-05  5.758476e-05  6.009076e-05
## ASV5591     -4.349280e-04 -4.545707e-04 -4.750511e-04 -4.964005e-04
## ASV6040     -3.480175e-04 -3.638134e-04 -3.802897e-04 -3.974726e-04
## ASV3904     -1.449721e-04 -1.517740e-04 -1.588895e-04 -1.663324e-04
## ASV2267     -4.077931e-05 -4.265228e-05 -4.460742e-05 -4.664791e-05
## ASV0573     -3.237723e-04 -3.379859e-04 -3.527693e-04 -3.681404e-04
## ASV0851     -3.511302e-04 -3.670647e-04 -3.836849e-04 -4.010168e-04
## ASV7805      1.108277e-04  1.160915e-04  1.216042e-04  1.273774e-04
## ASV3379      4.679570e-04  4.887571e-04  5.104165e-04  5.329648e-04
## ASV0825      2.143076e-04  2.244547e-04  2.350773e-04  2.461970e-04
## ASV2461      2.453713e-04  2.563943e-04  2.678827e-04  2.798539e-04
## ASV2783      3.430811e-04  3.586433e-04  3.748755e-04  3.918033e-04
## ASV0925      3.830629e-04  4.001196e-04  4.178812e-04  4.363721e-04
## ASV7023     -3.673283e-04 -3.842746e-04 -4.019768e-04 -4.204660e-04
## ASV5319      6.698469e-05  7.012653e-05  7.341208e-05  7.684745e-05
## ASV3213      2.293665e-04  2.399684e-04  2.510443e-04  2.626137e-04
## ASV3748     -5.786239e-05 -6.075484e-05 -6.379738e-05 -6.699819e-05
## ASV5491     -8.443744e-05 -8.855049e-05 -9.286767e-05 -9.739939e-05
## ASV7931      1.443562e-04  1.509971e-04  1.579319e-04  1.651724e-04
## ASV12767    -2.638540e-04 -2.761291e-04 -2.889616e-04 -3.023756e-04
## ASV6389      2.657111e-04  2.780266e-04  2.908969e-04  3.043455e-04
## ASV14867    -2.638273e-04 -2.760998e-04 -2.889296e-04 -3.023406e-04
## ASV5105      1.541002e-04  1.613837e-04  1.690076e-04  1.769873e-04
## ASV15927    -2.627653e-04 -2.749351e-04 -2.876523e-04 -3.009399e-04
## ASV2004      8.985142e-05  9.391289e-05  9.814861e-05  1.025653e-04
## ASV5554     -7.267048e-06 -8.190430e-06 -9.207176e-06 -1.032560e-05
## ASV10929    -1.839152e-04 -1.924424e-04 -2.013545e-04 -2.106680e-04
## ASV12778    -9.061418e-05 -9.478232e-05 -9.913551e-05 -1.036814e-04
## ASV14006    -2.627067e-04 -2.748709e-04 -2.875819e-04 -3.008628e-04
## ASV1603      2.570519e-04  2.690100e-04  2.815109e-04  2.945783e-04
## ASV11948     1.310314e-04  1.367621e-04  1.427196e-04  1.489107e-04
## ASV12912    -2.641401e-04 -2.764399e-04 -2.892991e-04 -3.027420e-04
## ASV13147    -2.641137e-04 -2.764110e-04 -2.892675e-04 -3.027074e-04
## ASV14761    -2.640874e-04 -2.763821e-04 -2.892359e-04 -3.026727e-04
## ASV8521      2.093843e-04  2.185870e-04  2.281581e-04  2.381090e-04
## ASV8581     -2.640696e-04 -2.763627e-04 -2.892145e-04 -3.026493e-04
## ASV9875     -4.583821e-05 -4.816071e-05 -5.060625e-05 -5.318171e-05
## ASV9986      1.753467e-04  1.835952e-04  1.922261e-04  2.012563e-04
## ASV2376      3.051311e-04  3.190105e-04  3.334911e-04  3.485962e-04
## ASV17535    -2.640510e-04 -2.763422e-04 -2.891920e-04 -3.026246e-04
## ASV14330    -2.535700e-04 -2.648893e-04 -2.766795e-04 -2.889572e-04
## ASV1333     -5.227025e-04 -5.452881e-04 -5.687480e-04 -5.931073e-04
## ASV2498      1.271649e-04  1.333236e-04  1.397820e-04  1.465546e-04
## ASV6352     -1.030286e-04 -1.074864e-04 -1.121171e-04 -1.169255e-04
## ASV8601     -1.295665e-04 -1.353224e-04 -1.413153e-04 -1.475534e-04
## ASV9776     -9.603979e-05 -1.001265e-04 -1.043647e-04 -1.087580e-04
## ASV1916      2.248446e-04  2.348937e-04  2.453631e-04  2.562681e-04
## ASV1555      2.900861e-05  3.049099e-05  3.205269e-05  3.369819e-05
## ASV2499      3.562749e-04  3.727874e-04  3.900435e-04  4.080747e-04
## ASV0703      2.931490e-04  3.066234e-04  3.206949e-04  3.353879e-04
## ASV2047      3.881458e-04  4.058070e-04  4.242341e-04  4.434568e-04
## ASV5492     -2.650987e-04 -2.774930e-04 -2.904560e-04 -3.040129e-04
## ASV6549     -2.739016e-05 -2.876478e-05 -3.021150e-05 -3.173436e-05
## ASV7757     -9.516433e-05 -9.989045e-05 -1.048587e-04 -1.100822e-04
## ASV0173     -2.678260e-06 -2.928170e-06 -3.200859e-06 -3.498325e-06
## ASV1248     -7.929750e-05 -8.274428e-05 -8.632514e-05 -9.004384e-05
## ASV6502      2.684789e-06  2.935251e-06  3.208533e-06  3.506637e-06
## ASV9844      2.684275e-06  2.934663e-06  3.207861e-06  3.505869e-06
## ASV3903      1.690097e-04  1.769396e-04  1.852356e-04  1.939140e-04
## ASV8199      2.670637e-06  2.919692e-06  3.191425e-06  3.487826e-06
## ASV3309     -1.162294e-05 -1.209478e-05 -1.258135e-05 -1.308262e-05
## ASV5826     -3.928115e-05 -4.122380e-05 -4.326463e-05 -4.540868e-05
## ASV1480     -3.546996e-04 -3.712904e-04 -3.886426e-04 -4.067899e-04
## ASV3090      7.487091e-05  7.823358e-05  8.173795e-05  8.538913e-05
## ASV0758     -2.126528e-04 -2.218433e-04 -2.313896e-04 -2.413020e-04
## ASV0811     -6.419565e-05 -6.698685e-05 -6.988755e-05 -7.290102e-05
## ASV2653      1.761613e-04  1.845057e-04  1.932418e-04  2.023875e-04
## ASV0978      1.822125e-04  1.908626e-04  1.999189e-04  2.093998e-04
## ASV6640     -3.665192e-04 -3.832804e-04 -4.007761e-04 -4.190356e-04
## ASV3423     -1.761126e-05 -1.865922e-05 -1.977648e-05 -2.096808e-05
## ASV0617      3.635687e-04  3.792457e-04  3.955301e-04  4.124398e-04
## ASV14947    -3.709547e-04 -3.880624e-04 -4.059317e-04 -4.245942e-04
## ASV18367    -2.046290e-04 -2.144409e-04 -2.247226e-04 -2.354961e-04
## ASV4574      2.811168e-04  2.933049e-04  3.059665e-04  3.191150e-04
## ASV10514    -1.984319e-04 -2.076984e-04 -2.173880e-04 -2.275191e-04
## ASV11779    -1.012085e-04 -1.064858e-04 -1.120512e-04 -1.179209e-04
## ASV7528     -3.213160e-04 -3.363241e-04 -3.520168e-04 -3.684237e-04
## ASV13153    -1.851221e-04 -1.938487e-04 -2.029810e-04 -2.125371e-04
## ASV7858     -1.643869e-04 -1.721344e-04 -1.802420e-04 -1.887257e-04
## ASV8722      5.476640e-05  5.695068e-05  5.920180e-05  6.151986e-05
## ASV6585     -3.701399e-04 -3.872031e-04 -4.050254e-04 -4.236380e-04
## ASV3311     -3.196704e-04 -3.336125e-04 -3.481034e-04 -3.631595e-04
## ASV2469      5.833357e-06  6.244097e-06  6.684477e-06  7.156520e-06
## ASV11340    -1.589775e-04 -1.659778e-04 -1.732607e-04 -1.808353e-04
## ASV1718      2.992880e-05  3.121010e-05  3.253915e-05  3.391707e-05
## ASV2117     -3.675190e-04 -3.845280e-04 -4.023001e-04 -4.208670e-04
## ASV8252     -2.608984e-04 -2.728965e-04 -2.854267e-04 -2.985106e-04
## ASV8533      5.117828e-05  5.351145e-05  5.594624e-05  5.848666e-05
## ASV9507      3.887473e-05  4.048298e-05  4.214631e-05  4.386551e-05
## ASV0706      1.868170e-04  1.957450e-04  2.051003e-04  2.149034e-04
## ASV10312    -2.608704e-04 -2.728658e-04 -2.853930e-04 -2.984737e-04
## ASV10696    -2.608446e-04 -2.728376e-04 -2.853622e-04 -2.984400e-04
## ASV11203    -2.608189e-04 -2.728095e-04 -2.853314e-04 -2.984064e-04
## ASV12147    -6.302531e-05 -6.608251e-05 -6.928997e-05 -7.265520e-05
## ASV4602     -1.703036e-05 -1.800125e-05 -1.903279e-05 -2.012910e-05
## ASV5568      1.405034e-05  1.479412e-05  1.557951e-05  1.640893e-05
## ASV6777      3.340422e-04  3.494323e-04  3.655073e-04  3.822955e-04
## ASV8749     -2.933109e-04 -3.066221e-04 -3.205073e-04 -3.349885e-04
## ASV4780      4.954937e-05  5.160111e-05  5.372281e-05  5.591541e-05
## ASV10116    -4.931161e-05 -5.154600e-05 -5.387699e-05 -5.630841e-05
## ASV2907      2.842631e-04  2.972708e-04  3.108483e-04  3.250182e-04
## ASV5165      3.723190e-04  3.900140e-04  4.085461e-04  4.279545e-04
## ASV6061      2.061959e-04  2.154884e-04  2.251760e-04  2.352733e-04
## ASV8082     -1.285017e-04 -1.344234e-04 -1.406093e-04 -1.470705e-04
## ASV7696     -1.309053e-04 -1.369476e-04 -1.432603e-04 -1.498547e-04
## ASV0550      2.585851e-05  2.694053e-05  2.806198e-05  2.922389e-05
## ASV7745      1.685256e-04  1.765959e-04  1.850530e-04  1.939154e-04
## ASV3607     -3.452879e-06 -3.549485e-06 -3.644723e-06 -3.738040e-06
## ASV3877     -2.535161e-04 -2.648380e-04 -2.766322e-04 -2.889155e-04
## ASV7667     -1.152788e-04 -1.203451e-04 -1.256158e-04 -1.310975e-04
## ASV9293     -9.749007e-05 -1.020463e-04 -1.068102e-04 -1.117908e-04
## ASV11653    -2.534736e-04 -2.647916e-04 -2.765816e-04 -2.888603e-04
## ASV12850     4.169410e-05  4.386211e-05  4.614679e-05  4.855445e-05
## ASV13104     4.725160e-05  4.918780e-05  5.118793e-05  5.325261e-05
## ASV14208    -2.534547e-04 -2.647711e-04 -2.765592e-04 -2.888359e-04
## ASV1552      2.356891e-04  2.468620e-04  2.585600e-04  2.708073e-04
## ASV2501      1.580452e-04  1.649691e-04  1.721696e-04  1.796556e-04
## ASV2893      3.168074e-04  3.314205e-04  3.466838e-04  3.626239e-04
## ASV3084      1.194027e-04  1.247063e-04  1.302294e-04  1.359796e-04
## ASV3599      1.603037e-04  1.673665e-04  1.747142e-04  1.823560e-04
## ASV3868     -2.534561e-04 -2.647727e-04 -2.765612e-04 -2.888382e-04
## ASV3917     -3.416997e-04 -3.570912e-04 -3.731363e-04 -3.898595e-04
## ASV5695      6.465785e-05  6.779773e-05  7.109141e-05  7.454642e-05
## ASV0131      3.272660e-05  3.384663e-05  3.498254e-05  3.613214e-05
## ASV2847      3.066332e-04  3.200983e-04  3.341035e-04  3.486661e-04
## ASV6875     -2.537164e-04 -2.651869e-04 -2.771478e-04 -2.896177e-04
## ASV1547     -5.234707e-04 -5.469145e-04 -5.713406e-04 -5.967843e-04
## ASV1501     -3.298598e-04 -3.448456e-04 -3.604794e-04 -3.767864e-04
## ASV3876      3.678018e-04  3.846204e-04  4.021751e-04  4.204951e-04
## ASV3456     -3.677657e-04 -3.845809e-04 -4.021320e-04 -4.204480e-04
## ASV1194      3.467573e-04  3.626015e-04  3.791382e-04  3.963949e-04
## ASV2135     -4.449420e-04 -4.655435e-04 -4.870706e-04 -5.095625e-04
## ASV1352      3.676656e-04  3.844714e-04  4.020122e-04  4.203170e-04
## ASV3208      4.183369e-04  4.374902e-04  4.574841e-04  4.783522e-04
## ASV1164      4.009567e-06  4.376430e-06  4.775352e-06  5.208939e-06
## ASV3492      1.764324e-04  1.849083e-04  1.937929e-04  2.031060e-04
## ASV1601      2.023134e-04  2.115505e-04  2.211908e-04  2.312502e-04
## ASV5347     -2.586908e-04 -2.702404e-04 -2.822715e-04 -2.948011e-04
## ASV0293      1.954572e-04  2.044104e-04  2.137567e-04  2.235118e-04
## ASV1509      3.370216e-04  3.523886e-04  3.684234e-04  3.851518e-04
## ASV2801      4.881645e-05  5.097834e-05  5.322914e-05  5.557197e-05
## ASV2873     -7.863145e-05 -8.236309e-05 -8.627129e-05 -9.036437e-05
## ASV2162     -5.240097e-05 -5.473584e-05 -5.716781e-05 -5.970033e-05
## ASV0462      2.022640e-04  2.109419e-04  2.199509e-04  2.293003e-04
## ASV5367     -3.194114e-04 -3.341830e-04 -3.496161e-04 -3.657383e-04
## ASV2715      3.981226e-04  4.161051e-04  4.348549e-04  4.544005e-04
## ASV0371      4.869555e-04  5.084347e-04  5.307885e-04  5.540466e-04
## ASV8090     -3.369083e-04 -3.520277e-04 -3.677832e-04 -3.841978e-04
## ASV6320     -2.642835e-04 -2.766017e-04 -2.894817e-04 -3.029481e-04
## ASV2562      2.777073e-04  2.906863e-04  3.042595e-04  3.184529e-04
## ASV1505     -3.890295e-04 -4.070475e-04 -4.258746e-04 -4.455448e-04
## ASV4924     -2.974110e-04 -3.108802e-04 -3.249267e-04 -3.395724e-04
## ASV1437      3.327809e-04  3.479919e-04  3.638688e-04  3.804379e-04
## ASV3816     -2.119073e-05 -2.185665e-05 -2.252596e-05 -2.319676e-05
## ASV1969     -1.624702e-04 -1.703182e-04 -1.785422e-04 -1.871595e-04
## ASV3146      1.759639e-04  1.836969e-04  1.917408e-04  2.001054e-04
## ASV0321     -1.908504e-04 -1.993566e-04 -2.082173e-04 -2.174452e-04
## ASV1020      3.847596e-04  4.019730e-04  4.199071e-04  4.385879e-04
## ASV4138      2.759750e-05  2.906162e-05  3.060788e-05  3.224108e-05
## ASV0329     -2.137502e-04 -2.235891e-04 -2.338637e-04 -2.445915e-04
## ASV10647     3.873455e-05  4.061814e-05  4.259468e-05  4.466884e-05
## ASV3389      3.182678e-04  3.328574e-04  3.480888e-04  3.639879e-04
## ASV6880      1.693984e-04  1.765083e-04  1.838725e-04  1.914960e-04
## ASV2624     -4.419292e-05 -4.664937e-05 -4.925307e-05 -5.201344e-05
## ASV3686     -6.387274e-05 -6.764534e-05 -7.165958e-05 -7.593176e-05
## ASV12302    -2.663047e-04 -2.788108e-04 -2.918958e-04 -3.055856e-04
## ASV1184      3.245588e-04  3.392793e-04  3.546329e-04  3.706434e-04
## ASV3533     -1.377636e-04 -1.435964e-04 -1.496411e-04 -1.559019e-04
## ASV1735      7.663971e-05  7.986210e-05  8.319959e-05  8.665439e-05
## ASV0483     -1.511351e-04 -1.582319e-04 -1.656558e-04 -1.734213e-04
## ASV0928     -2.997686e-04 -3.136318e-04 -3.281167e-04 -3.432494e-04
## ASV12254    -2.631821e-04 -2.753918e-04 -2.881526e-04 -3.014880e-04
## ASV16025    -2.631560e-04 -2.753632e-04 -2.881212e-04 -3.014537e-04
## ASV3070     -2.631298e-04 -2.753345e-04 -2.880899e-04 -3.014193e-04
## ASV1850      6.224236e-05  6.524968e-05  6.840300e-05  7.170933e-05
## ASV8946     -2.574416e-04 -2.691092e-04 -2.812776e-04 -2.939658e-04
## ASV1536      2.156833e-04  2.254137e-04  2.355575e-04  2.461301e-04
## ASV4151      3.242420e-04  3.387849e-04  3.539394e-04  3.697276e-04
## ASV4585      4.353633e-04  4.548813e-04  4.752186e-04  4.964045e-04
## ASV4921     -1.050068e-04 -1.096229e-04 -1.144226e-04 -1.194114e-04
## ASV6172      2.573728e-04  2.690340e-04  2.811955e-04  2.938763e-04
## ASV6375     -2.573477e-04 -2.690067e-04 -2.811657e-04 -2.938437e-04
## ASV6501      2.913922e-04  3.041832e-04  3.174884e-04  3.313243e-04
## ASV17095    -2.573282e-04 -2.689853e-04 -2.811424e-04 -2.938182e-04
## ASV3679     -2.573032e-04 -2.689580e-04 -2.811125e-04 -2.937856e-04
## ASV5750      2.572782e-04  2.689307e-04  2.810827e-04  2.937531e-04
## ASV5922     -2.572532e-04 -2.689034e-04 -2.810529e-04 -2.937205e-04
## ASV7323     -2.572283e-04 -2.688761e-04 -2.810231e-04 -2.936879e-04
## ASV8515     -3.810914e-06 -4.036289e-06 -4.275000e-06 -4.527731e-06
## ASV8753     -2.572029e-04 -2.688484e-04 -2.809928e-04 -2.936549e-04
## ASV9197      1.769308e-04  1.849957e-04  1.934107e-04  2.021893e-04
## ASV1778      4.894792e-05  5.142623e-05  5.403507e-05  5.678163e-05
## ASV1241      3.313468e-04  3.461979e-04  3.616723e-04  3.777924e-04
## ASV1717      2.594496e-04  2.712207e-04  2.834992e-04  2.963047e-04
## ASV1112      2.963158e-04  3.092915e-04  3.227841e-04  3.368098e-04
## ASV3994      3.500434e-04  3.661311e-04  3.829288e-04  4.004649e-04
## ASV5511     -2.587781e-04 -2.705731e-04 -2.828809e-04 -2.957216e-04
## ASV8706      1.892977e-04  1.982546e-04  2.076315e-04  2.174475e-04
## ASV3049     -2.587577e-04 -2.705509e-04 -2.828566e-04 -2.956951e-04
## ASV4332      1.668693e-04  1.746547e-04  1.827947e-04  1.913044e-04
## ASV7411      2.919915e-04  3.049090e-04  3.183528e-04  3.323405e-04
## ASV7475     -2.587473e-04 -2.705394e-04 -2.828442e-04 -2.956815e-04
## ASV8988     -2.587220e-04 -2.705118e-04 -2.828140e-04 -2.956485e-04
## ASV0688     -5.499707e-04 -5.743102e-04 -5.996434e-04 -6.260035e-04
## ASV1946      1.475586e-04  1.538212e-04  1.603155e-04  1.670473e-04
## ASV3150      4.290954e-04  4.483859e-04  4.684904e-04  4.894383e-04
## ASV3508      2.085769e-04  2.176400e-04  2.270573e-04  2.368388e-04
## ASV3863     -2.587040e-04 -2.704920e-04 -2.827923e-04 -2.956248e-04
## ASV4544      2.018103e-04  2.105661e-04  2.196627e-04  2.291098e-04
## ASV4567      4.665119e-04  4.876949e-04  5.097922e-04  5.328388e-04
## ASV4855     -2.586777e-04 -2.704633e-04 -2.827609e-04 -2.955905e-04
## ASV4872      3.440980e-04  3.594937e-04  3.755324e-04  3.922366e-04
## ASV4881      2.497265e-04  2.614306e-04  2.736736e-04  2.864792e-04
## ASV5283      2.586571e-04  2.704408e-04  2.827363e-04  2.955636e-04
## ASV5302      3.050697e-04  3.188589e-04  3.332409e-04  3.482390e-04
## ASV5909      2.593068e-04  2.710586e-04  2.833148e-04  2.960944e-04
## ASV5933      1.937065e-04  2.025217e-04  2.117185e-04  2.213116e-04
## ASV6019      2.846144e-04  2.969958e-04  3.098637e-04  3.232328e-04
## ASV6043      1.159125e-04  1.213872e-04  1.271175e-04  1.331149e-04
## ASV6908      3.239842e-04  3.386761e-04  3.539999e-04  3.699794e-04
## ASV7245     -2.586708e-04 -2.704557e-04 -2.827526e-04 -2.955813e-04
## ASV7249     -2.586455e-04 -2.704281e-04 -2.827224e-04 -2.955484e-04
## ASV8349      8.744386e-05  9.150743e-05  9.575481e-05  1.001938e-04
## ASV7310     -2.586248e-04 -2.704054e-04 -2.826976e-04 -2.955213e-04
## ASV1893      1.999684e-04  2.089359e-04  2.182821e-04  2.280210e-04
## ASV2354      1.525009e-04  1.590002e-04  1.657433e-04  1.727366e-04
## ASV3435     -4.257127e-05 -4.433381e-05 -4.615680e-05 -4.804115e-05
## ASV0480      4.033496e-04  4.221474e-04  4.417987e-04  4.623399e-04
## ASV0955     -1.400988e-04 -1.466285e-04 -1.534559e-04 -1.605940e-04
## ASV10000     7.687273e-05  7.991489e-05  8.304803e-05  8.627211e-05
## ASV7215     -1.681049e-04 -1.759839e-04 -1.842247e-04 -1.928430e-04
## ASV10423    -3.660549e-04 -3.827089e-04 -4.000838e-04 -4.182075e-04
## ASV6008     -1.956651e-04 -2.045946e-04 -2.139130e-04 -2.236357e-04
## ASV9330     -3.660025e-04 -3.826515e-04 -4.000211e-04 -4.181391e-04
## ASV6051      3.659668e-04  3.826125e-04  3.999785e-04  4.180925e-04
## ASV1675      2.418729e-04  2.528586e-04  2.643181e-04  2.762696e-04
## ASV2043      1.577853e-04  1.652117e-04  1.729831e-04  1.811148e-04
## ASV3634      1.490717e-04  1.562545e-04  1.637862e-04  1.716842e-04
## ASV4077     -3.659498e-04 -3.825940e-04 -3.999583e-04 -4.180706e-04
## ASV4754      1.766404e-04  1.845501e-04  1.927910e-04  2.013749e-04
## ASV6095      4.182518e-04  4.368322e-04  4.561792e-04  4.763193e-04
## ASV6288      3.098034e-04  3.236760e-04  3.381288e-04  3.531825e-04
## ASV6507     -3.659278e-04 -3.825700e-04 -3.999321e-04 -4.180419e-04
## ASV8905      1.853643e-04  1.936638e-04  2.023112e-04  2.113190e-04
## ASV9728     -3.658982e-04 -3.825376e-04 -3.998967e-04 -4.180032e-04
## ASV11144    -3.658625e-04 -3.824986e-04 -3.998541e-04 -4.179566e-04
## ASV1615     -1.475950e-04 -1.544154e-04 -1.615403e-04 -1.689823e-04
## ASV2709     -4.460547e-04 -4.662793e-04 -4.873733e-04 -5.093694e-04
## ASV3003      3.547066e-04  3.710540e-04  3.881295e-04  4.059634e-04
## ASV5163     -3.371388e-04 -3.524477e-04 -3.684167e-04 -3.850708e-04
## ASV6622      2.378082e-04  2.488748e-04  2.604439e-04  2.725373e-04
## ASV1076     -3.496119e-04 -3.655967e-04 -3.822810e-04 -3.996926e-04
## ASV7895      8.208864e-05  8.564088e-05  8.932985e-05  9.315921e-05
## ASV10577    -2.661712e-04 -2.786658e-04 -2.917383e-04 -3.054148e-04
## ASV1272      2.661444e-04  2.786364e-04  2.917062e-04  3.053795e-04
## ASV2492     -1.334675e-04 -1.402543e-04 -1.474016e-04 -1.549296e-04
## ASV5195      3.185543e-04  3.331847e-04  3.484621e-04  3.644129e-04
## ASV5267      1.910668e-04  1.996140e-04  2.085174e-04  2.177895e-04
## ASV6317      2.717471e-04  2.843848e-04  2.975949e-04  3.114021e-04
## ASV2296      9.755750e-05  1.020633e-04  1.067717e-04  1.116916e-04
## ASV2290     -2.378304e-04 -2.484060e-04 -2.594183e-04 -2.708823e-04
## ASV3726      2.086420e-04  2.184809e-04  2.287780e-04  2.395542e-04
## ASV1169      1.752768e-04  1.831946e-04  1.914506e-04  2.000575e-04
## ASV0189     -1.691106e-04 -1.771137e-04 -1.854921e-04 -1.942631e-04
## ASV2729      6.388601e-04  6.687254e-04  6.999565e-04  7.326128e-04
## ASV3469      1.450244e-04  1.517286e-04  1.587334e-04  1.660514e-04
## ASV0762     -3.434188e-04 -3.586852e-04 -3.745806e-04 -3.911264e-04
## ASV9001     -3.159915e-04 -3.295598e-04 -3.436496e-04 -3.582762e-04
## ASV14604    -2.563141e-04 -2.678801e-04 -2.799383e-04 -2.925068e-04
## ASV7439      7.697399e-05  8.076507e-05  8.474756e-05  8.893144e-05
## ASV8625     -2.562937e-04 -2.678579e-04 -2.799141e-04 -2.924805e-04
## ASV11553     5.118805e-05  5.375070e-05  5.644632e-05  5.928210e-05
## ASV14440     4.848999e-06  4.594840e-06  4.288188e-06  3.923538e-06
## ASV16106    -2.562720e-04 -2.678341e-04 -2.798881e-04 -2.924520e-04
## ASV16110    -2.562472e-04 -2.678070e-04 -2.798585e-04 -2.924198e-04
## ASV2229      4.507978e-04  4.707326e-04  4.914803e-04  5.130681e-04
## ASV3854     -2.480124e-04 -2.592068e-04 -2.708777e-04 -2.830430e-04
## ASV5512     -2.562137e-04 -2.677705e-04 -2.798186e-04 -2.923761e-04
## ASV5939      3.446415e-04  3.603387e-04  3.767172e-04  3.938033e-04
## ASV6676     -1.771295e-04 -1.851260e-04 -1.934631e-04 -2.021533e-04
## ASV8381     -2.561578e-04 -2.677094e-04 -2.797518e-04 -2.923033e-04
## ASV2735      3.268919e-04  3.418645e-04  3.574940e-04  3.738063e-04
## ASV9816     -2.561412e-04 -2.676913e-04 -2.797321e-04 -2.922817e-04
## ASV1382      1.145209e-04  1.194816e-04  1.246356e-04  1.299887e-04
## ASV1408     -2.572885e-04 -2.689522e-04 -2.811179e-04 -2.938049e-04
## ASV4902      1.654301e-04  1.734612e-04  1.818872e-04  1.907277e-04
## ASV5600      1.988299e-04  2.078103e-04  2.171744e-04  2.269365e-04
## ASV0815     -5.510000e-05 -5.744484e-05 -5.987653e-05 -6.239714e-05
## ASV11867    -2.572759e-04 -2.689386e-04 -2.811030e-04 -2.937886e-04
## ASV16064    -2.572509e-04 -2.689112e-04 -2.810732e-04 -2.937560e-04
## ASV2250      3.238901e-04  3.387664e-04  3.543005e-04  3.705192e-04
## ASV2417      7.662066e-05  8.035394e-05  8.427139e-05  8.838216e-05
## ASV2807      4.179782e-04  4.363894e-04  4.555457e-04  4.754719e-04
## ASV3224     -2.571938e-04 -2.688489e-04 -2.810052e-04 -2.936819e-04
## ASV4115     -2.571688e-04 -2.688216e-04 -2.809754e-04 -2.936493e-04
## ASV4876      4.190247e-05  4.374000e-05  4.564981e-05  4.763391e-05
## ASV5291      2.496247e-04  2.607308e-04  2.722948e-04  2.843324e-04
## ASV5834      1.214701e-04  1.269806e-04  1.327277e-04  1.387203e-04
## ASV6896      2.779485e-05  2.892422e-05  3.008977e-05  3.129170e-05
## ASV7292     -2.571531e-04 -2.688044e-04 -2.809566e-04 -2.936288e-04
## ASV7924      1.483990e-04  1.552676e-04  1.624445e-04  1.699425e-04
## ASV0710      3.395098e-04  3.547197e-04  3.705662e-04  3.870720e-04
## ASV1925      2.950353e-04  3.081224e-04  3.217460e-04  3.359242e-04
## ASV4247     -2.571261e-04 -2.687749e-04 -2.809244e-04 -2.935937e-04
## ASV4549     -2.571011e-04 -2.687476e-04 -2.808946e-04 -2.935611e-04
## ASV4076      2.152951e-04  2.250733e-04  2.352745e-04  2.459151e-04
## ASV7063      2.095970e-04  2.192295e-04  2.292868e-04  2.397860e-04
## ASV1487      2.205299e-04  2.301872e-04  2.402293e-04  2.506684e-04
## ASV1405      9.295904e-05  9.741280e-05  1.020800e-04  1.069708e-04
## ASV3851      2.296045e-04  2.403434e-04  2.515732e-04  2.633150e-04
## ASV0896      6.986957e-05  7.309171e-05  7.645767e-05  7.997346e-05
## ASV5581      3.344237e-04  3.501702e-04  3.666488e-04  3.838925e-04
## ASV7053     -1.095738e-04 -1.145770e-04 -1.197988e-04 -1.252479e-04
## ASV7171     -2.638177e-04 -2.760899e-04 -2.889195e-04 -3.023305e-04
## ASV4017     -3.608117e-04 -3.775009e-04 -3.949390e-04 -4.131573e-04
## ASV5846      1.993200e-05  2.019589e-05  2.041442e-05  2.058097e-05
## ASV0203      1.554701e-06  1.437209e-06  1.301901e-06  1.147507e-06
## ASV13271     3.991838e-05  4.149831e-05  4.312567e-05  4.480047e-05
## ASV9487      1.619577e-04  1.686094e-04  1.754875e-04  1.825957e-04
## ASV2056     -3.693177e-04 -3.863066e-04 -4.040485e-04 -4.225743e-04
## ASV16933    -3.622497e-04 -3.785699e-04 -3.955837e-04 -4.133168e-04
## ASV0360      1.565576e-04  1.633993e-04  1.705139e-04  1.779101e-04
## ASV1798     -2.355553e-04 -2.461568e-04 -2.572075e-04 -2.687239e-04
## ASV17286    -2.634664e-04 -2.757017e-04 -2.884904e-04 -3.018560e-04
## ASV8175     -2.634402e-04 -2.756730e-04 -2.884589e-04 -3.018216e-04
## ASV6679      2.774922e-04  2.899914e-04  3.030202e-04  3.165981e-04
## ASV6776      1.333042e-04  1.391521e-04  1.452333e-04  1.515551e-04
## ASV9062     -2.634163e-04 -2.756469e-04 -2.884303e-04 -3.017902e-04
## ASV9564     -2.391995e-05 -2.518839e-05 -2.652901e-05 -2.794630e-05
## ASV6431     -2.633881e-04 -2.756160e-04 -2.883964e-04 -3.017531e-04
## ASV9940      1.069007e-04  1.117170e-04  1.167368e-04  1.219675e-04
## ASV7001     -3.628312e-04 -3.791912e-04 -3.962463e-04 -4.140222e-04
## ASV3044      4.097146e-04  4.281910e-04  4.474540e-04  4.675330e-04
## ASV6684      1.531884e-04  1.605672e-04  1.683036e-04  1.764148e-04
## ASV12278     2.868581e-06  3.129478e-06  3.413213e-06  3.721661e-06
## ASV3543     -2.409430e-04 -2.513920e-04 -2.622501e-04 -2.735299e-04
## ASV6397      2.863355e-06  3.123759e-06  3.406955e-06  3.714816e-06
## ASV9939      2.862818e-06  3.123148e-06  3.406259e-06  3.714023e-06
## ASV9432      2.132859e-04  2.233481e-04  2.338793e-04  2.449008e-04
## ASV2630     -2.648011e-04 -2.771717e-04 -2.901080e-04 -3.036348e-04
## ASV2175      3.476797e-04  3.639508e-04  3.809696e-04  3.987691e-04
## ASV4107      2.861227e-04  2.993545e-04  3.131789e-04  3.276207e-04
## ASV9172     -3.727817e-05 -3.923551e-05 -4.130243e-05 -4.348557e-05
## ASV3141      3.415733e-04  3.576625e-04  3.745004e-04  3.921208e-04
## ASV9010     -2.642352e-04 -2.765443e-04 -2.894138e-04 -3.028680e-04
## ASV2550      2.607462e-04  2.726189e-04  2.850065e-04  2.979290e-04
## ASV5845     -2.642171e-04 -2.765245e-04 -2.893920e-04 -3.028441e-04
## ASV3998      2.641907e-04  2.764956e-04  2.893604e-04  3.028094e-04
## ASV1389     -2.810822e-04 -2.930975e-04 -3.055690e-04 -3.185096e-04
## ASV0615     -2.971710e-04 -3.107097e-04 -3.248375e-04 -3.395774e-04
## ASV9127     -3.640378e-04 -3.805560e-04 -3.977859e-04 -4.157546e-04
## ASV1190      5.155615e-04  5.384002e-04  5.621737e-04  5.869135e-04
## ASV1211      1.304412e-04  1.363679e-04  1.425521e-04  1.490042e-04
## ASV1766     -3.748300e-04 -3.919737e-04 -4.098681e-04 -4.285427e-04
## ASV2337      2.611719e-04  2.731840e-04  2.857280e-04  2.988252e-04
## ASV2463      5.622065e-05  5.880274e-05  6.149861e-05  6.431281e-05
## ASV2806      1.936262e-04  2.021869e-04  2.110993e-04  2.203758e-04
## ASV0439     -3.360379e-04 -3.514023e-04 -3.674385e-04 -3.841729e-04
## ASV0839      3.217146e-04  3.368603e-04  3.527081e-04  3.692891e-04
## ASV14975    -2.611263e-04 -2.731342e-04 -2.856734e-04 -2.987656e-04
## ASV17712    -2.611006e-04 -2.731060e-04 -2.856426e-04 -2.987319e-04
## ASV2010     -2.942129e-05 -3.068955e-05 -3.200555e-05 -3.337039e-05
## ASV2041      1.379843e-04  1.446617e-04  1.516644e-04  1.590080e-04
## ASV2124     -3.370607e-04 -3.526135e-04 -3.688596e-04 -3.858277e-04
## ASV2585      4.654969e-04  4.867109e-04  5.088465e-04  5.319394e-04
## ASV3314      3.696561e-04  3.868379e-04  4.047979e-04  4.235696e-04
## ASV5051     -3.316112e-05 -3.444279e-05 -3.575780e-05 -3.710526e-05
## ASV10784     1.306108e-04  1.365049e-04  1.426502e-04  1.490560e-04
## ASV3279     -2.610384e-04 -2.730380e-04 -2.855682e-04 -2.986505e-04
## ASV9498      1.746470e-05  1.807916e-05  1.870412e-05  1.933858e-05
## ASV1059     -2.793436e-04 -2.924066e-04 -3.060688e-04 -3.203565e-04
## ASV13008    -2.610120e-04 -2.730090e-04 -2.855365e-04 -2.986158e-04
## ASV15803    -2.609862e-04 -2.729809e-04 -2.855057e-04 -2.985821e-04
## ASV2559     -2.533531e-04 -2.650104e-04 -2.771844e-04 -2.898964e-04
## ASV2623     -2.609612e-04 -2.729535e-04 -2.854757e-04 -2.985493e-04
## ASV2802     -1.463480e-04 -1.529786e-04 -1.598941e-04 -1.671051e-04
## ASV3799      3.999870e-04  4.181285e-04  4.370512e-04  4.567850e-04
## ASV5274     -1.026133e-06 -1.236060e-06 -1.469872e-06 -1.729819e-06
## ASV5835      1.616190e-04  1.692358e-04  1.772081e-04  1.855523e-04
## ASV7251     -2.609553e-04 -2.729470e-04 -2.854686e-04 -2.985416e-04
## ASV7616     -2.609296e-04 -2.729189e-04 -2.854379e-04 -2.985079e-04
## ASV9576     -2.609039e-04 -2.728908e-04 -2.854071e-04 -2.984743e-04
## ASV2870      1.912820e-04  2.000918e-04  2.092924e-04  2.188999e-04
## ASV3668     -1.684661e-04 -1.763191e-04 -1.845291e-04 -1.931114e-04
## ASV1633      1.276709e-04  1.336915e-04  1.399925e-04  1.465865e-04
## ASV6060     -6.846333e-06 -7.666478e-06 -8.566220e-06 -9.552292e-06
## ASV6305      1.318848e-04  1.380793e-04  1.445601e-04  1.513400e-04
## ASV5164      8.437200e-05  8.797854e-05  9.171982e-05  9.559908e-05
## ASV7252     -2.616389e-04 -2.737018e-04 -2.863020e-04 -2.994618e-04
## ASV9343      2.268284e-04  2.376397e-04  2.489655e-04  2.608301e-04
## ASV6835     -4.348031e-05 -4.540776e-05 -4.741401e-05 -4.950170e-05
## ASV1264      3.178236e-04  3.322724e-04  3.473472e-04  3.630725e-04
## ASV0591      2.632884e-05  2.705967e-05  2.778072e-05  2.848802e-05
## ASV1351      3.680226e-04  3.850094e-04  4.027546e-04  4.212896e-04
## ASV14224    -2.615752e-04 -2.736321e-04 -2.862258e-04 -2.993784e-04
## ASV1432     -2.615493e-04 -2.736038e-04 -2.861948e-04 -2.993445e-04
## ASV1559     -2.195114e-04 -2.297201e-04 -2.403914e-04 -2.515452e-04
## ASV2182      4.052713e-04  4.236754e-04  4.428738e-04  4.628970e-04
## ASV2304     -2.149390e-05 -2.239948e-05 -2.333759e-05 -2.430888e-05
## ASV6838     -2.161411e-06 -2.236751e-06 -2.313330e-06 -2.391023e-06
## ASV1125     -3.955434e-05 -4.147696e-05 -4.349427e-05 -4.561099e-05
## ASV17948    -2.615400e-04 -2.735936e-04 -2.861837e-04 -2.993324e-04
## ASV2609      2.311412e-04  2.419212e-04  2.531927e-04  2.649769e-04
## ASV6128     -2.147418e-04 -2.246854e-04 -2.350698e-04 -2.459121e-04
## ASV1338      5.010806e-05  5.198192e-05  5.390041e-05  5.586204e-05
## ASV2136      9.389675e-05  9.792550e-05  1.021074e-04  1.064467e-04
## ASV0929     -2.379800e-04 -2.487361e-04 -2.599526e-04 -2.716469e-04
## ASV3479      1.637055e-04  1.709743e-04  1.785414e-04  1.864166e-04
## ASV0886      4.389246e-04  4.590072e-04  4.799697e-04  5.018469e-04
## ASV1652      2.018513e-04  2.111812e-04  2.209294e-04  2.311133e-04
## ASV1160      3.646699e-04  3.814825e-04  3.990439e-04  4.173851e-04
## ASV5260     -6.999917e-05 -7.352348e-05 -7.723106e-05 -8.113172e-05
## ASV2352      4.441266e-04  4.636893e-04  4.840445e-04  5.052184e-04
## ASV0986     -1.765592e-04 -1.844524e-04 -1.926757e-04 -2.012410e-04
## ASV2021      2.935855e-04  3.069056e-04  3.207996e-04  3.352896e-04
## ASV16599    -2.438086e-04 -2.557375e-04 -2.682556e-04 -2.813917e-04
## ASV3497      2.239874e-04  2.343909e-04  2.452658e-04  2.566326e-04
## ASV1305      1.517431e-04  1.590666e-04  1.667433e-04  1.747898e-04
## ASV0927     -3.385671e-04 -3.528805e-04 -3.677177e-04 -3.830909e-04
## ASV0647     -1.107256e-04 -1.152177e-04 -1.198554e-04 -1.246401e-04
## ASV1832     -1.457573e-04 -1.523209e-04 -1.591631e-04 -1.662944e-04
## ASV1277      1.738813e-04  1.817833e-04  1.900268e-04  1.986249e-04
## ASV22332    -2.622849e-04 -2.744079e-04 -2.870738e-04 -3.003052e-04
## ASV10080    -3.527180e-05 -3.753107e-05 -3.994556e-05 -4.252612e-05
## ASV14157     3.563352e-05  3.738705e-05  3.922888e-05  4.116358e-05
## ASV15829    -2.622578e-04 -2.743782e-04 -2.870411e-04 -3.002693e-04
## ASV3609     -2.622318e-04 -2.743497e-04 -2.870100e-04 -3.002353e-04
## ASV5737      5.735398e-05  5.973357e-05  6.219481e-05  6.473887e-05
## ASV1474      1.914941e-04  2.004011e-04  2.097106e-04  2.194398e-04
## ASV2028      2.575359e-04  2.684263e-04  2.797155e-04  2.914128e-04
## ASV0818      3.146761e-04  3.290697e-04  3.440933e-04  3.597718e-04
## ASV0505     -2.730743e-04 -2.857629e-04 -2.990239e-04 -3.128814e-04
## ASV1813      1.272432e-04  1.327407e-04  1.384501e-04  1.443770e-04
## ASV0512      2.844982e-04  2.979468e-04  3.120189e-04  3.267417e-04
## ASV5374     -2.006376e-04 -2.099073e-04 -2.195932e-04 -2.297130e-04
## ASV2927     -2.368336e-05 -2.421523e-05 -2.471944e-05 -2.519022e-05
## ASV3596      1.951564e-04  2.037207e-04  2.126273e-04  2.218870e-04
## ASV1137      1.161176e-04  1.211041e-04  1.262786e-04  1.316458e-04
## ASV4541      3.546806e-06  3.872144e-06  4.226340e-06  4.611820e-06
## ASV9872     -3.546137e-06 -3.871380e-06 -4.225469e-06 -4.610827e-06
## ASV0359     -9.127678e-05 -9.524725e-05 -9.937305e-05 -1.036587e-04
## ASV0720     -1.561960e-04 -1.630863e-04 -1.702547e-04 -1.777102e-04
## ASV10545    -3.560921e-06 -3.887454e-06 -4.242938e-06 -4.629802e-06
## ASV13384    -3.560249e-06 -3.886687e-06 -4.242064e-06 -4.628806e-06
## ASV1456      6.744695e-06  7.023505e-06  7.311973e-06  7.610274e-06
## ASV1751     -3.559957e-06 -3.886333e-06 -4.241637e-06 -4.628294e-06
## ASV18419    -3.559286e-06 -3.885567e-06 -4.240763e-06 -4.627297e-06
## ASV2970      3.558614e-06  3.884801e-06  4.239889e-06  4.626302e-06
## ASV4215      2.043332e-04  2.136665e-04  2.234068e-04  2.335701e-04
## ASV4742      3.307208e-05  3.432721e-05  3.561445e-05  3.693311e-05
## ASV5017      6.396319e-05  6.675369e-05  6.965425e-05  7.266819e-05
## ASV5139     -3.554113e-06 -3.879774e-06 -4.234275e-06 -4.620030e-06
## ASV9133     -3.553443e-06 -3.879010e-06 -4.233403e-06 -4.619036e-06
## ASV9447     -3.552773e-06 -3.878245e-06 -4.232531e-06 -4.618042e-06
## ASV0842     -1.918798e-04 -2.000232e-04 -2.084691e-04 -2.172250e-04
## ASV12293     1.338814e-04  1.394005e-04  1.451089e-04  1.510098e-04
## ASV1965      2.463275e-04  2.577600e-04  2.697091e-04  2.821970e-04
## ASV2005      2.655812e-04  2.768806e-04  2.886005e-04  3.007514e-04
## ASV5335      1.982291e-04  2.068149e-04  2.157335e-04  2.249945e-04
## ASV6438     -3.589196e-06 -3.917862e-06 -4.275603e-06 -4.664853e-06
## ASV7798     -3.588520e-06 -3.917090e-06 -4.274724e-06 -4.663850e-06
## ASV2691     -2.770962e-04 -2.898929e-04 -3.032606e-04 -3.172230e-04
## ASV9958      2.255772e-04  2.357098e-04  2.462695e-04  2.572717e-04
## ASV1512      8.275790e-05  8.671431e-05  9.086066e-05  9.520614e-05
## ASV1226      3.711651e-04  3.880389e-04  4.056437e-04  4.240079e-04
## ASV2130     -6.546687e-04 -6.843876e-04 -7.153885e-04 -7.477207e-04
## ASV0874     -2.035616e-04 -2.127550e-04 -2.223435e-04 -2.323424e-04
## ASV5436     -2.919338e-04 -3.053468e-04 -3.193520e-04 -3.339734e-04
## ASV0383     -3.187006e-04 -3.324406e-04 -3.467085e-04 -3.615189e-04
## ASV1882      3.117745e-04  3.252482e-04  3.392455e-04  3.537818e-04
## ASV2471     -1.774289e-04 -1.854688e-04 -1.938544e-04 -2.025987e-04
## ASV4049     -2.518250e-04 -2.631678e-04 -2.749916e-04 -2.873140e-04
## ASV3014     -1.403650e-04 -1.465013e-04 -1.528812e-04 -1.595120e-04
## ASV0316     -5.052417e-04 -5.281970e-04 -5.521442e-04 -5.771216e-04
## ASV1621     -3.496152e-04 -3.652385e-04 -3.815140e-04 -3.984649e-04
## ASV13266    -2.571576e-04 -2.688051e-04 -2.809527e-04 -2.936192e-04
## ASV1635     -2.549826e-04 -2.665276e-04 -2.785678e-04 -2.911220e-04
## ASV2042      1.873486e-04  1.958471e-04  2.047117e-04  2.139566e-04
## ASV2317     -3.054451e-04 -3.192205e-04 -3.335819e-04 -3.485510e-04
## ASV3697      2.303077e-04  2.405367e-04  2.511871e-04  2.622732e-04
## ASV6404      4.233936e-04  4.420895e-04  4.615474e-04  4.817931e-04
## ASV15616     1.837037e-05  1.943191e-05  2.056016e-05  2.175958e-05
## ASV10783    -2.571042e-04 -2.687468e-04 -2.808890e-04 -2.935496e-04
## ASV6912     -1.926889e-04 -2.013467e-04 -2.103698e-04 -2.197712e-04
## ASV1561      5.198649e-04  5.429485e-04  5.669828e-04  5.920005e-04
## ASV4404      3.552657e-04  3.713099e-04  3.880387e-04  4.054779e-04
## ASV1110      2.605030e-04  2.721496e-04  2.842823e-04  2.969181e-04
## ASV2844     -8.913319e-05 -9.340197e-05 -9.787528e-05 -1.025629e-04
## ASV5224      2.603616e-04  2.721089e-04  2.843557e-04  2.971203e-04
## ASV6300     -2.618728e-04 -2.739561e-04 -2.865786e-04 -2.997623e-04
## ASV8078     -2.618469e-04 -2.739278e-04 -2.865475e-04 -2.997284e-04
## ASV9722      1.861176e-07 -1.037935e-07 -4.337755e-07 -8.079016e-07
## ASV6911     -2.618206e-04 -2.738990e-04 -2.865160e-04 -2.996938e-04
## ASV5474     -5.400646e-05 -5.661838e-05 -5.935766e-05 -6.223052e-05
## ASV2761     -6.118816e-04 -6.395049e-04 -6.683058e-04 -6.983282e-04
## ASV5943     -1.717347e-04 -1.799956e-04 -1.886565e-04 -1.977370e-04
## ASV0600     -4.280498e-05 -4.423689e-05 -4.568508e-05 -4.714625e-05
## ASV0608     -5.485460e-04 -5.731740e-04 -5.988411e-04 -6.255853e-04
## ASV1586      1.316083e-04  1.373518e-04  1.433237e-04  1.495312e-04
## ASV0206     -6.074107e-04 -6.341008e-04 -6.618632e-04 -6.907322e-04
## ASV4042     -2.795036e-04 -2.921877e-04 -3.054185e-04 -3.192167e-04
## ASV5304     -8.596866e-06 -9.066816e-06 -9.563414e-06 -1.008813e-05
## ASV0949     -9.938789e-05 -1.045923e-04 -1.100832e-04 -1.158773e-04
## ASV1856      3.220613e-04  3.367094e-04  3.519912e-04  3.679311e-04
## ASV2584      3.747184e-05  3.900090e-05  4.057855e-05  4.220486e-05
## ASV2287     -1.768440e-05 -1.899696e-05 -2.040882e-05 -2.192711e-05
## ASV2364     -4.564236e-04 -4.770087e-04 -4.984703e-04 -5.208410e-04
## ASV11481    -3.656749e-04 -3.827529e-04 -4.006115e-04 -4.192848e-04
## ASV2906     -1.273532e-04 -1.333378e-04 -1.395989e-04 -1.461487e-04
## ASV0161     -1.512813e-04 -1.580891e-04 -1.651848e-04 -1.725787e-04
## ASV0062     -9.946046e-04 -1.039469e-03 -1.086242e-03 -1.134994e-03
## ASV3811     -2.322958e-04 -2.419670e-04 -2.519829e-04 -2.623512e-04
## ASV0225      3.784315e-05  3.911729e-05  4.040892e-05  4.171574e-05
## ASV4672     -3.181401e-04 -3.322781e-04 -3.469994e-04 -3.623241e-04
## ASV1607     -2.449741e-05 -2.566298e-05 -2.688143e-05 -2.815475e-05
## ASV3060      6.369720e-05  6.677246e-05  6.999758e-05  7.337994e-05
## ASV2275     -4.554810e-05 -4.761283e-05 -4.976618e-05 -5.201149e-05
## ASV5375      1.792797e-04  1.877088e-04  1.965286e-04  2.057565e-04
## ASV0352     -5.345579e-04 -5.592763e-04 -5.851024e-04 -6.120825e-04
## ASV1107      1.548007e-04  1.621697e-04  1.698851e-04  1.779626e-04
## ASV4887      1.373422e-04  1.431901e-04  1.492552e-04  1.555428e-04
## ASV2397     -6.868922e-05 -7.144117e-05 -7.427868e-05 -7.720210e-05
## ASV7541     -1.668871e-04 -1.743598e-04 -1.821450e-04 -1.902536e-04
## ASV7387     -3.659175e-04 -3.825733e-04 -3.999508e-04 -4.180776e-04
## ASV1355      3.360763e-04  3.515325e-04  3.676747e-04  3.845312e-04
## ASV1764     -1.746383e-04 -1.824709e-04 -1.906333e-04 -1.991374e-04
## ASV1960     -3.183679e-04 -3.317577e-04 -3.456352e-04 -3.600121e-04
## ASV0484     -6.183553e-05 -6.464445e-05 -6.757505e-05 -7.063211e-05
## ASV2487      9.829349e-05  1.022472e-04  1.063265e-04  1.105323e-04
## ASV0422      3.101654e-04  3.234352e-04  3.372101e-04  3.515042e-04
## ASV0081     -1.970602e-04 -2.063799e-04 -2.161366e-04 -2.263503e-04
## ASV1341     -1.675794e-04 -1.747864e-04 -1.822686e-04 -1.900333e-04
## ASV1001     -3.970208e-04 -4.142262e-04 -4.321009e-04 -4.506643e-04
## ASV0317     -9.779862e-05 -1.025415e-04 -1.075133e-04 -1.127247e-04
## ASV2728     -2.776103e-04 -2.902060e-04 -3.033450e-04 -3.170482e-04
## ASV0884     -3.590023e-04 -3.761362e-04 -3.940851e-04 -4.128871e-04
## ASV0464      7.875567e-05  8.305798e-05  8.761234e-05  9.243447e-05
## ASV2963      2.422055e-04  2.529377e-04  2.641109e-04  2.757404e-04
## ASV4608      1.097850e-04  1.147560e-04  1.199398e-04  1.253444e-04
## ASV3534      2.697595e-04  2.811820e-04  2.930244e-04  3.052964e-04
## ASV0291     -2.340061e-04 -2.444085e-04 -2.552392e-04 -2.665126e-04
## ASV0635     -3.400278e-04 -3.558487e-04 -3.723879e-04 -3.896764e-04
## ASV0867      2.745714e-04  2.875876e-04  3.012166e-04  3.154867e-04
## ASV1206     -3.106879e-05 -3.231115e-05 -3.359144e-05 -3.490969e-05
## ASV1230     -2.368500e-06 -2.590619e-06 -2.833097e-06 -3.097731e-06
## ASV1265      7.254124e-05  7.582944e-05  7.925935e-05  8.283647e-05
## ASV1291     -2.249657e-04 -2.354511e-04 -2.464139e-04 -2.578747e-04
## ASV1524      4.596095e-04  4.797414e-04  5.006766e-04  5.224404e-04
## ASV2153     -3.546348e-04 -3.701804e-04 -3.863491e-04 -4.031610e-04
## ASV2714      2.332129e-06  2.551002e-06  2.789958e-06  3.050772e-06
## ASV4246     -2.331680e-06 -2.550488e-06 -2.789370e-06 -3.050100e-06
## ASV0945      2.373984e-04  2.481561e-04  2.593753e-04  2.710736e-04
## ASV2380      5.487158e-04  5.728143e-04  5.978821e-04  6.239506e-04
## ASV0214     -7.999871e-05 -8.284905e-05 -8.575445e-05 -8.871140e-05
## ASV10461    -2.371347e-06 -2.593793e-06 -2.836635e-06 -3.101675e-06
## ASV4177      1.593676e-04  1.660428e-04  1.729562e-04  1.801127e-04
## ASV0237     -4.006878e-04 -4.192357e-04 -4.386160e-04 -4.588635e-04
## ASV11323    -4.519114e-04 -4.726467e-04 -4.942975e-04 -5.169010e-04
## ASV2232     -7.733605e-05 -8.068562e-05 -8.416508e-05 -8.777813e-05
## ASV0115     -1.454087e-04 -1.520069e-04 -1.588885e-04 -1.660640e-04
## ASV1171      6.593332e-05  6.846263e-05  7.106008e-05  7.372476e-05
## ASV1942      3.131037e-04  3.274846e-04  3.425022e-04  3.581823e-04
## ASV1889      3.100521e-05  3.232304e-05  3.368915e-05  3.510456e-05
## ASV0920      7.009310e-05  7.347801e-05  7.702738e-05  8.074916e-05
## ASV1805     -4.004745e-04 -4.186041e-04 -4.375113e-04 -4.572258e-04
## ASV1712      2.391479e-04  2.497528e-04  2.607910e-04  2.722770e-04
## ASV1458      3.506707e-04  3.660385e-04  3.820232e-04  3.986450e-04
## ASV1985      3.740521e-04  3.908499e-04  4.083573e-04  4.266005e-04
## ASV2960     -2.361339e-04 -2.459239e-04 -2.560591e-04 -2.665466e-04
## ASV5207     -6.998043e-05 -7.234285e-05 -7.473976e-05 -7.716733e-05
## ASV8548     -2.361086e-04 -2.458967e-04 -2.560296e-04 -2.665148e-04
## ASV0449     -1.447112e-04 -1.516133e-04 -1.588386e-04 -1.664012e-04
## ASV0609     -3.230630e-04 -3.374777e-04 -3.524901e-04 -3.681211e-04
## ASV1038      1.226701e-04  1.277226e-04  1.329471e-04  1.383460e-04
## ASV1145     -7.358650e-05 -7.650696e-05 -7.951708e-05 -8.261730e-05
## ASV15767    -2.361039e-04 -2.458917e-04 -2.560244e-04 -2.665093e-04
## ASV1630      3.350443e-04  3.495295e-04  3.645798e-04  3.802122e-04
## ASV1911      4.212079e-04  4.404006e-04  4.604279e-04  4.813225e-04
## ASV1950      3.015183e-04  3.143848e-04  3.277388e-04  3.415940e-04
## ASV2583      2.360305e-04  2.458120e-04  2.559380e-04  2.664156e-04
## ASV2853     -3.489765e-04 -3.641773e-04 -3.799802e-04 -3.964042e-04
## ASV2948      2.359868e-04  2.457645e-04  2.558864e-04  2.663596e-04
## ASV3116     -3.795283e-04 -3.958011e-04 -4.126953e-04 -4.302285e-04
## ASV3160     -2.023801e-04 -2.106035e-04 -2.191012e-04 -2.278776e-04
## ASV3354      2.534184e-04  2.650097e-04  2.771063e-04  2.897277e-04
## ASV3368      2.359269e-04  2.456997e-04  2.558162e-04  2.662836e-04
## ASV3464     -2.359061e-04 -2.456771e-04 -2.557917e-04 -2.662572e-04
## ASV3577      2.358853e-04  2.456546e-04  2.557673e-04  2.662307e-04
## ASV3746      3.099357e-04  3.231280e-04  3.368141e-04  3.510068e-04
## ASV3942      1.053099e-04  1.106460e-04  1.162609e-04  1.221695e-04
## ASV4000      2.358508e-04  2.456172e-04  2.557268e-04  2.661870e-04
## ASV4207      4.296336e-04  4.496558e-04  4.705885e-04  4.924711e-04
## ASV4261      2.358328e-04  2.455977e-04  2.557058e-04  2.661643e-04
## ASV4466      9.014751e-05  9.503282e-05  1.001948e-04  1.056491e-04
## ASV4487     -2.358192e-04 -2.455832e-04 -2.556903e-04 -2.661476e-04
## ASV4572     -1.791651e-04 -1.867791e-04 -1.946796e-04 -2.028743e-04
## ASV4718      2.357846e-04  2.455457e-04  2.556496e-04  2.661036e-04
## ASV4757     -2.357638e-04 -2.455231e-04 -2.556252e-04 -2.660771e-04
## ASV4929     -2.357430e-04 -2.455006e-04 -2.556008e-04 -2.660507e-04
## ASV5611     -2.357222e-04 -2.454781e-04 -2.555764e-04 -2.660243e-04
## ASV5614     -2.357014e-04 -2.454555e-04 -2.555520e-04 -2.659979e-04
## ASV5898      2.061029e-04  2.151701e-04  2.246022e-04  2.344108e-04
## ASV7627     -4.932983e-05 -5.078929e-05 -5.224735e-05 -5.369906e-05
## ASV3105     -1.288482e-04 -1.339631e-04 -1.392391e-04 -1.446779e-04
## ASV4762     -3.490908e-04 -3.643100e-04 -3.801334e-04 -3.965799e-04
## ASV5622      2.356487e-04  2.453984e-04  2.554902e-04  2.659311e-04
## ASV7129      3.100629e-04  3.238734e-04  3.382568e-04  3.532333e-04
## ASV12138    -2.356201e-04 -2.453674e-04 -2.554566e-04 -2.658947e-04
## ASV1687     -3.554118e-04 -3.712487e-04 -3.877475e-04 -4.049325e-04
## ASV2187      1.745499e-04  1.816802e-04  1.890527e-04  1.966719e-04
## ASV2204      3.594854e-04  3.753816e-04  3.919250e-04  4.091372e-04
## ASV2914      2.763962e-04  2.880397e-04  3.001106e-04  3.126196e-04
## ASV3297     -2.355441e-04 -2.452849e-04 -2.553671e-04 -2.657976e-04
## ASV3310     -3.038020e-04 -3.167458e-04 -3.301778e-04 -3.441112e-04
## ASV3677      2.083581e-05  2.259207e-05  2.449109e-05  2.654346e-05
## ASV4508      2.354996e-04  2.452368e-04  2.553150e-04  2.657414e-04
## ASV6236     -1.128422e-04 -1.170101e-04 -1.212789e-04 -1.256463e-04
## ASV6285      2.354706e-04  2.452055e-04  2.552812e-04  2.657049e-04
## ASV7576     -2.354499e-04 -2.451830e-04 -2.552568e-04 -2.656785e-04
## ASV7917     -2.354291e-04 -2.451605e-04 -2.552325e-04 -2.656522e-04
## ASV9353     -2.354084e-04 -2.451380e-04 -2.552082e-04 -2.656259e-04
## ASV1656      3.937098e-04  4.109986e-04  4.289828e-04  4.476849e-04
## ASV0280     -3.776486e-04 -3.952623e-04 -4.136796e-04 -4.329355e-04
## ASV4747      7.745846e-06  8.479633e-06  9.281249e-06  1.015674e-05
## ASV2108     -4.625809e-04 -4.839825e-04 -5.063456e-04 -5.297107e-04
## ASV0885      1.548618e-04  1.619516e-04  1.693530e-04  1.770786e-04
## ASV2538     -1.249321e-04 -1.303965e-04 -1.360777e-04 -1.419823e-04
## ASV0968      2.846013e-04  2.974175e-04  3.107767e-04  3.246991e-04
## ASV1229     -2.556522e-04 -2.671528e-04 -2.791391e-04 -2.916286e-04
## ASV13306    -2.556276e-04 -2.671259e-04 -2.791097e-04 -2.915966e-04
## ASV13952     1.549848e-04  1.615700e-04  1.683998e-04  1.754801e-04
## ASV14631     1.440302e-04  1.511327e-04  1.585951e-04  1.664362e-04
## ASV2119      2.997768e-04  3.125039e-04  3.257023e-04  3.393836e-04
## ASV2450      2.670165e-04  2.792469e-04  2.920153e-04  3.053435e-04
## ASV2656     -2.556180e-04 -2.671155e-04 -2.790985e-04 -2.915844e-04
## ASV2942     -1.838927e-05 -1.916764e-05 -1.997406e-05 -2.080906e-05
## ASV3302      2.275428e-04  2.376332e-04  2.481364e-04  2.590661e-04
## ASV6515      8.665002e-05  9.014296e-05  9.374820e-05  9.746687e-05
## ASV6674     -2.555978e-04 -2.670934e-04 -2.790743e-04 -2.915580e-04
## ASV7296     -9.516804e-05 -9.959390e-05 -1.042195e-04 -1.090533e-04
## ASV7903      1.394119e-04  1.453886e-04  1.515929e-04  1.580310e-04
## ASV7943     -2.555719e-04 -2.670651e-04 -2.790433e-04 -2.915241e-04
## ASV8864      1.852755e-04  1.927199e-04  2.004010e-04  2.083208e-04
## ASV9389      2.202633e-05  2.240700e-05  2.275053e-05  2.305107e-05
## ASV9869     -2.555544e-04 -2.670458e-04 -2.790221e-04 -2.915008e-04
## ASV1051      2.555297e-04  2.670189e-04  2.789928e-04  2.914688e-04
## ASV13035    -1.095948e-05 -1.135728e-05 -1.176302e-05 -1.217618e-05
## ASV15744     8.341298e-06  9.167162e-06  1.007072e-05  1.105894e-05
## ASV2526      2.615384e-05  2.706633e-05  2.799476e-05  2.893786e-05
## ASV1156      1.334652e-04  1.393812e-04  1.455398e-04  1.519493e-04
## ASV13562    -2.555158e-04 -2.670038e-04 -2.789763e-04 -2.914508e-04
## ASV1438      2.246167e-04  2.350547e-04  2.459665e-04  2.573730e-04
## ASV2268     -2.555033e-04 -2.669901e-04 -2.789614e-04 -2.914347e-04
## ASV2797      1.238479e-04  1.297579e-04  1.359497e-04  1.424370e-04
## ASV3744      2.857347e-04  2.988669e-04  3.125790e-04  3.268942e-04
## ASV8076     -2.753872e-04 -2.877921e-04 -3.007224e-04 -3.141972e-04
## ASV7055      1.197548e-04  1.256307e-04  1.318010e-04  1.382809e-04
## ASV7493     -2.336449e-04 -2.442474e-04 -2.553067e-04 -2.668402e-04
## ASV1201      5.675881e-04  5.930440e-04  6.195699e-04  6.472046e-04
## ASV5736     -4.926234e-04 -5.151891e-04 -5.387459e-04 -5.633334e-04
## ASV0558      2.390475e-04  2.502030e-04  2.618662e-04  2.740590e-04
## ASV14399    -3.402090e-04 -3.554387e-04 -3.713064e-04 -3.878352e-04
## ASV2992     -1.917965e-05 -2.001906e-05 -2.089177e-05 -2.179879e-05
## ASV4303     -2.500659e-04 -2.613039e-04 -2.730155e-04 -2.852178e-04
## ASV0565     -2.852197e-04 -2.981799e-04 -3.117018e-04 -3.258076e-04
## ASV0977     -4.213538e-04 -4.394134e-04 -4.581624e-04 -4.776205e-04
## ASV0140      2.137544e-04  2.233584e-04  2.333675e-04  2.437964e-04
## ASV14421    -2.566836e-04 -2.682869e-04 -2.803861e-04 -2.929999e-04
## ASV16909    -5.759425e-05 -6.034334e-05 -6.322313e-05 -6.623971e-05
## ASV3762     -2.566540e-04 -2.682545e-04 -2.803507e-04 -2.929612e-04
## ASV7141     -2.566291e-04 -2.682273e-04 -2.803210e-04 -2.929288e-04
## ASV3291      4.091024e-04  4.279832e-04  4.477069e-04  4.683085e-04
## ASV10440    -2.566002e-04 -2.681958e-04 -2.802866e-04 -2.928912e-04
## ASV10802     7.809140e-05  8.155480e-05  8.516009e-05  8.891206e-05
## ASV1698      4.335315e-05  4.547198e-05  4.769638e-05  5.003174e-05
## ASV2121      2.565819e-04  2.681758e-04  2.802647e-04  2.928673e-04
## ASV3549     -3.625273e-04 -3.789684e-04 -3.961165e-04 -4.139987e-04
## ASV6379      3.018379e-04  3.150891e-04  3.288720e-04  3.432039e-04
## ASV6824     -2.565271e-04 -2.681159e-04 -2.801994e-04 -2.927960e-04
## ASV8254      2.709980e-05  2.845700e-05  2.988431e-05  3.138546e-05
## ASV9951      1.136728e-04  1.190428e-04  1.246639e-04  1.305473e-04
## ASV1515     -1.065816e-04 -1.111416e-04 -1.158723e-04 -1.207778e-04
## ASV4327      7.831316e-05  8.186580e-05  8.557177e-05  8.943700e-05
## ASV0341     -1.198833e-04 -1.255508e-04 -1.314831e-04 -1.376922e-04
## ASV5562     -2.105690e-04 -2.204219e-04 -2.307274e-04 -2.415057e-04
## ASV1412      5.752128e-04  6.014109e-04  6.287483e-04  6.572697e-04
## ASV0154     -4.636238e-04 -4.849873e-04 -5.073020e-04 -5.306075e-04
## ASV3163     -2.137022e-04 -2.232764e-04 -2.332533e-04 -2.436476e-04
## ASV1782     -3.411394e-04 -3.566045e-04 -3.727332e-04 -3.895505e-04
## ASV3993     -3.623983e-05 -3.765246e-05 -3.910494e-05 -4.059692e-05
## ASV3164      1.632302e-04  1.703497e-04  1.777491e-04  1.854369e-04
## ASV1024      2.148979e-05  2.266383e-05  2.390741e-05  2.522501e-05
## ASV0771     -4.646833e-04 -4.852054e-04 -5.065606e-04 -5.287764e-04
## ASV2223     -2.079636e-04 -2.178448e-04 -2.281900e-04 -2.390200e-04
## ASV1638      7.703513e-04  8.048833e-04  8.408656e-04  8.783503e-04
## ASV0232     -2.262666e-04 -2.364565e-04 -2.470788e-04 -2.581494e-04
## ASV6771     -2.519274e-04 -2.636946e-04 -2.759976e-04 -2.888595e-04
## ASV4243     -9.760081e-05 -1.017040e-04 -1.059590e-04 -1.103701e-04
## ASV0162     -4.624674e-04 -4.834291e-04 -5.052894e-04 -5.280818e-04
## ASV0049      3.203608e-05  3.351563e-05  3.506164e-05  3.667696e-05
## ASV4697     -2.579658e-04 -2.696864e-04 -2.819132e-04 -2.946658e-04
## ASV12326     8.138911e-05  8.482693e-05  8.838983e-05  9.208058e-05
## ASV12586    -2.579445e-04 -2.696631e-04 -2.818877e-04 -2.946379e-04
## ASV1879      2.042875e-04  2.135883e-04  2.232920e-04  2.334140e-04
## ASV2864      5.640127e-04  5.899447e-04  6.170256e-04  6.453022e-04
## ASV3111     -1.499040e-04 -1.566840e-04 -1.637541e-04 -1.711253e-04
## ASV5633     -1.436790e-04 -1.501300e-04 -1.568527e-04 -1.638570e-04
## ASV5864      8.548294e-05  8.878505e-05  9.217834e-05  9.566190e-05
## ASV6364      1.249017e-04  1.308392e-04  1.370579e-04  1.435708e-04
## ASV1598      1.594048e-04  1.666930e-04  1.743020e-04  1.822452e-04
## ASV2649     -9.597704e-05 -1.006847e-04 -1.056272e-04 -1.108164e-04
## ASV4664      2.114672e-04  2.208126e-04  2.305393e-04  2.406602e-04
## ASV2654      3.573816e-04  3.735256e-04  3.903580e-04  4.079045e-04
## ASV6636     -2.621449e-05 -2.780803e-05 -2.950489e-05 -3.131183e-05
## ASV3334      2.680302e-04  2.806620e-04  2.938807e-04  3.077128e-04
## ASV0046     -4.772492e-04 -4.996021e-04 -5.229823e-04 -5.474349e-04
## ASV0661      4.792273e-04  5.005395e-04  5.227323e-04  5.458362e-04
## ASV0774      2.159240e-04  2.257612e-04  2.360252e-04  2.467322e-04
## ASV3815      2.572973e-04  2.688071e-04  2.807973e-04  2.932848e-04
## ASV0575      2.581286e-04  2.693461e-04  2.810039e-04  2.931154e-04
## ASV1953     -3.590429e-04 -3.753336e-04 -3.923249e-04 -4.100436e-04
## ASV0610      1.076134e-04  1.123188e-04  1.172115e-04  1.222977e-04
## ASV0245     -1.313263e-04 -1.373367e-04 -1.436108e-04 -1.501592e-04
## ASV3805     -1.864152e-04 -1.938879e-04 -2.016006e-04 -2.095562e-04
## ASV1182      5.380263e-04  5.630517e-04  5.892126e-04  6.165580e-04
## ASV1941      1.518214e-06  1.662283e-06  1.819782e-06  1.991921e-06
## ASV0080     -6.300470e-04 -6.585085e-04 -6.881841e-04 -7.191190e-04
## ASV1033      1.883631e-04  1.969271e-04  2.058616e-04  2.151810e-04
## ASV5330     -2.259189e-04 -2.360418e-04 -2.465887e-04 -2.575747e-04
## ASV9702     -3.433514e-04 -3.580314e-04 -3.732687e-04 -3.890785e-04
## ASV0358      8.580469e-06  8.759025e-06  8.925899e-06  9.078875e-06
## ASV2225      1.786878e-04  1.867091e-04  1.950678e-04  2.037759e-04
## ASV2606      7.529809e-06  7.673353e-06  7.804376e-06  7.920623e-06
## ASV3510     -2.787981e-04 -2.914576e-04 -3.046632e-04 -3.184360e-04
## ASV3069      9.416792e-05  9.804833e-05  1.020629e-04  1.062142e-04
## ASV3849      1.722945e-04  1.798512e-04  1.877095e-04  1.958787e-04
## ASV1810     -4.328826e-04 -4.516112e-04 -4.710704e-04 -4.912821e-04
## ASV2046      6.407801e-04  6.701158e-04  7.007386e-04  7.326999e-04
## ASV2451     -7.897923e-05 -8.300086e-05 -8.723420e-05 -9.169061e-05
## ASV4047      3.339036e-04  3.489459e-04  3.646272e-04  3.809712e-04
## ASV7402     -2.650929e-04 -2.774534e-04 -2.903750e-04 -3.038816e-04
## ASV8250      3.250904e-04  3.401493e-04  3.558856e-04  3.723275e-04
## ASV3468      2.780382e-04  2.905526e-04  3.035971e-04  3.171912e-04
## ASV3521      5.728469e-04  5.989750e-04  6.262419e-04  6.546925e-04
## ASV6363     -1.955562e-04 -2.047719e-04 -2.144145e-04 -2.245026e-04
## ASV6444      1.308218e-04  1.369994e-04  1.434672e-04  1.502388e-04
## ASV8231      1.499633e-04  1.566239e-04  1.635592e-04  1.707787e-04
## ASV0196     -8.571210e-04 -8.957909e-04 -9.361071e-04 -9.781310e-04
## ASV12801    -2.651056e-04 -2.774671e-04 -2.903899e-04 -3.038977e-04
## ASV12906    -2.650791e-04 -2.774381e-04 -2.903581e-04 -3.038629e-04
## ASV13040    -2.650526e-04 -2.774091e-04 -2.903263e-04 -3.038281e-04
## ASV1313     -2.798757e-05 -2.961885e-05 -3.135275e-05 -3.319604e-05
## ASV14008     7.544638e-05  7.916768e-05  8.307932e-05  8.719170e-05
## ASV1546      1.005179e-04  1.046697e-04  1.089640e-04  1.134032e-04
## ASV1637      4.955470e-04  5.179877e-04  5.413901e-04  5.657905e-04
## ASV17076     2.142471e-04  2.236576e-04  2.334453e-04  2.436221e-04
## ASV2061      7.356503e-04  7.683951e-04  8.024943e-04  8.379948e-04
## ASV2177      3.064369e-04  3.208746e-04  3.359838e-04  3.517945e-04
## ASV2943      4.485539e-04  4.687187e-04  4.897340e-04  5.116307e-04
## ASV3020      3.949254e-04  4.125346e-04  4.308742e-04  4.499694e-04
## ASV30254     1.815349e-05  1.857946e-05  1.898936e-05  1.937972e-05
## ASV3219      5.543085e-04  5.790811e-04  6.048873e-04  6.317639e-04
## ASV3352      4.858263e-04  5.080546e-04  5.312582e-04  5.554760e-04
## ASV3355      2.090376e-04  2.187840e-04  2.289723e-04  2.396211e-04
## ASV3377      3.773152e-04  3.945515e-04  4.125421e-04  4.313171e-04
## ASV3449      2.181784e-04  2.276720e-04  2.375383e-04  2.477885e-04
## ASV3893      2.650237e-04  2.773772e-04  2.902912e-04  3.037893e-04
## ASV4326      1.535336e-04  1.600818e-04  1.668750e-04  1.739194e-04
## ASV5016     -2.650049e-04 -2.773566e-04 -2.902685e-04 -3.037645e-04
## ASV5152      2.030544e-04  2.115184e-04  2.202811e-04  2.293482e-04
## ASV5666     -1.091679e-05 -1.165153e-05 -1.243822e-05 -1.328046e-05
## ASV5802     -2.714354e-04 -2.840633e-04 -2.972620e-04 -3.110555e-04
## ASV6070      1.866327e-04  1.947462e-04  2.031774e-04  2.119359e-04
## ASV6488      1.627017e-04  1.699807e-04  1.775640e-04  1.854626e-04
## ASV6562     -2.649613e-04 -2.773087e-04 -2.902159e-04 -3.037068e-04
## ASV6930      1.915797e-04  1.999212e-04  2.085906e-04  2.175977e-04
## ASV7243      3.478394e-04  3.632886e-04  3.793733e-04  3.961153e-04
## ASV7506      2.207289e-04  2.304189e-04  2.404971e-04  2.509759e-04
## ASV7553     -2.649416e-04 -2.772871e-04 -2.901922e-04 -3.036808e-04
## ASV8064      1.499991e-04  1.565921e-04  1.634494e-04  1.705792e-04
## ASV8434     -1.477756e-04 -1.548202e-04 -1.621977e-04 -1.699232e-04
## ASV8858     -2.649092e-04 -2.772515e-04 -2.901533e-04 -3.036380e-04
## ASV2600      1.524453e-04  1.595445e-04  1.669647e-04  1.747193e-04
## ASV3398      5.721235e-04  5.983099e-04  6.256461e-04  6.541780e-04
## ASV4584     -2.648705e-04 -2.772092e-04 -2.901068e-04 -3.035872e-04
## ASV4864      2.889587e-04  3.020246e-04  3.156495e-04  3.298546e-04
## ASV0082     -1.128830e-03 -1.180001e-03 -1.233373e-03 -1.289031e-03
## ASV9626      2.333580e-04  2.439971e-04  2.550985e-04  2.666803e-04
## ASV1617      1.003096e-04  1.043544e-04  1.085290e-04  1.128347e-04
## ASV2765     -6.123692e-05 -6.431190e-05 -6.754504e-05 -7.094452e-05
## ASV2167     -3.504904e-04 -3.663481e-04 -3.828847e-04 -4.001259e-04
## ASV1628      2.196023e-04  2.287954e-04  2.383184e-04  2.481782e-04
## ASV3260     -5.490755e-05 -5.719211e-05 -5.955610e-05 -6.200086e-05
## ASV3645      3.352510e-05  3.533254e-05  3.724050e-05  3.925443e-05
## ASV6057     -3.344809e-04 -3.496226e-04 -3.654135e-04 -3.818785e-04
## ASV0662     -4.408243e-05 -4.590304e-05 -4.778622e-05 -4.973299e-05
## ASV4267     -4.320762e-05 -4.529659e-05 -4.748605e-05 -4.978063e-05
## ASV1070      3.590135e-04  3.757662e-04  3.932841e-04  4.116007e-04
## ASV0633     -9.197873e-05 -9.596642e-05 -1.001093e-04 -1.044120e-04
## ASV0333      3.675170e-04  3.843837e-04  4.019958e-04  4.203838e-04
## ASV0966      2.792541e-04  2.920193e-04  3.053421e-04  3.192443e-04
## ASV1848      4.041248e-04  4.230635e-04  4.428741e-04  4.635951e-04
## ASV13390    -2.559599e-04 -2.674956e-04 -2.795210e-04 -2.920542e-04
## ASV14901    -2.559352e-04 -2.674686e-04 -2.794915e-04 -2.920220e-04
## ASV1676     -2.930679e-04 -3.059076e-04 -3.192593e-04 -3.331389e-04
## ASV1756     -3.083764e-05 -3.221028e-05 -3.363942e-05 -3.512696e-05
## ASV22537    -3.503912e-05 -3.650019e-05 -3.801276e-05 -3.957782e-05
## ASV3303     -4.589853e-06 -4.908269e-06 -5.249523e-06 -5.615191e-06
## ASV4030     -1.065605e-04 -1.112604e-04 -1.161504e-04 -1.212367e-04
## ASV4871      2.052992e-04  2.147570e-04  2.246358e-04  2.349530e-04
## ASV5536      1.267409e-05  1.325083e-05  1.385301e-05  1.448170e-05
## ASV5700      9.169504e-05  9.585031e-05  1.001836e-04  1.047014e-04
## ASV8957      1.674471e-04  1.742884e-04  1.813582e-04  1.886599e-04
## ASV11210     1.654656e-04  1.734944e-04  1.819177e-04  1.907551e-04
## ASV7585     -2.559258e-04 -2.674583e-04 -2.794803e-04 -2.920098e-04
## ASV8596     -2.559011e-04 -2.674313e-04 -2.794508e-04 -2.919777e-04
## ASV9532     -1.023057e-04 -1.067790e-04 -1.114296e-04 -1.162628e-04
## ASV4254      1.860008e-04  1.945922e-04  2.035675e-04  2.129427e-04
## ASV13299    -2.558793e-04 -2.674076e-04 -2.794250e-04 -2.919495e-04
## ASV15627    -2.558545e-04 -2.673806e-04 -2.793955e-04 -2.919173e-04
## ASV6302     -2.006956e-04 -2.088733e-04 -2.173265e-04 -2.260599e-04
## ASV3040      1.031333e-04  1.078362e-04  1.127436e-04  1.178634e-04
## ASV0632      2.101951e-04  2.198358e-04  2.299020e-04  2.404112e-04
## ASV3694      3.337731e-04  3.489190e-04  3.647173e-04  3.811929e-04
## ASV1592     -6.117554e-05 -6.357211e-05 -6.603914e-05 -6.857662e-05
## ASV0538      1.710152e-04  1.790400e-04  1.874366e-04  1.962220e-04
## ASV0832      3.726333e-04  3.894834e-04  4.070546e-04  4.253744e-04
## ASV0727      2.830002e-04  2.962473e-04  3.101031e-04  3.245947e-04
## ASV1165     -3.622702e-04 -3.788421e-04 -3.961409e-04 -4.141956e-04
## ASV1325      4.316435e-05  4.597705e-05  4.899032e-05  5.221924e-05
## ASV0819      6.499429e-04  6.796299e-04  7.106155e-04  7.429511e-04
## ASV2251      3.435512e-04  3.578512e-04  3.726532e-04  3.879664e-04
## ASV0100     -2.214019e-05 -2.309987e-05 -2.409642e-05 -2.513080e-05
## ASV0444     -1.733124e-04 -1.812431e-04 -1.895237e-04 -1.981686e-04
## ASV0800      8.448857e-04  8.822263e-04  9.210896e-04  9.615266e-04
## ASV2432      1.817628e-05  1.866547e-05  1.914802e-05  1.962160e-05
## ASV2883      2.295051e-05  2.376358e-05  2.459064e-05  2.543032e-05
## ASV3894      2.566288e-05  2.643186e-05  2.719800e-05  2.795798e-05
## ASV2367      5.928798e-04  6.196506e-04  6.475638e-04  6.766624e-04
## ASV3724     -3.520582e-04 -3.678132e-04 -3.842273e-04 -4.013241e-04
## ASV2112     -3.014945e-04 -3.152774e-04 -3.296627e-04 -3.446740e-04
## ASV3661      1.047649e-04  1.096768e-04  1.148152e-04  1.201904e-04
## ASV2096     -2.193464e-04 -2.296792e-04 -2.404891e-04 -2.517969e-04
## ASV3551     -2.513213e-04 -2.623821e-04 -2.738873e-04 -2.858510e-04
## ASV11343    -9.067870e-06 -9.633068e-06 -1.023703e-05 -1.088261e-05
## ASV2051      2.170159e-04  2.270482e-04  2.375326e-04  2.484886e-04
## ASV2617     -2.970136e-04 -3.104230e-04 -3.244040e-04 -3.389779e-04
## ASV0125     -1.317454e-04 -1.377716e-04 -1.440609e-04 -1.506234e-04
## ASV0372      4.526727e-04  4.731112e-04  4.944211e-04  5.166352e-04
## ASV6751     -3.376086e-04 -3.526616e-04 -3.683398e-04 -3.846650e-04
## ASV10810     7.586117e-05  7.932568e-05  8.294276e-05  8.671874e-05
## ASV0461     -1.938890e-04 -2.028692e-04 -2.122531e-04 -2.220578e-04
## ASV1945     -1.153179e-04 -1.207527e-04 -1.264403e-04 -1.323920e-04
## ASV0882     -9.993671e-05 -1.050277e-04 -1.103882e-04 -1.160330e-04
## ASV4040     -4.926415e-05 -5.149776e-05 -5.382570e-05 -5.625119e-05
## ASV0109     -3.224399e-06 -3.330517e-06 -3.437197e-06 -3.544053e-06
## ASV0174      1.499337e-04  1.560827e-04  1.624366e-04  1.689979e-04
## ASV2851      2.584021e-04  2.695283e-04  2.810794e-04  2.930668e-04
## ASV5312      4.397236e-05  4.595197e-05  4.801837e-05  5.017540e-05
## ASV9402     -3.621682e-04 -3.783977e-04 -3.953079e-04 -4.129231e-04
## ASV4870     -2.922580e-04 -3.052578e-04 -3.187944e-04 -3.328865e-04
## ASV0589      3.503678e-04  3.662475e-04  3.828099e-04  4.000811e-04
## ASV1221      9.624247e-07  1.046903e-06  1.138360e-06  1.237314e-06
## ASV6028     -3.388239e-04 -3.541270e-04 -3.700840e-04 -3.867195e-04
## ASV5106     -1.268265e-04 -1.323570e-04 -1.381059e-04 -1.440796e-04
## ASV4977     -4.776270e-05 -5.043468e-05 -5.326637e-05 -5.626770e-05
## ASV5715     -2.226717e-04 -2.327474e-04 -2.432552e-04 -2.542114e-04
## ASV4182      8.545715e-05  8.973295e-05  9.423056e-05  9.896203e-05
## ASV2383     -2.001227e-05 -2.138755e-05 -2.286620e-05 -2.445635e-05
## ASV3985      4.016256e-04  4.202858e-04  4.397909e-04  4.601770e-04
## ASV2787     -2.989122e-04 -3.119871e-04 -3.255837e-04 -3.397185e-04
## ASV6756     -2.592480e-04 -2.711525e-04 -2.835820e-04 -2.965574e-04
## ASV1634     -4.125136e-04 -4.307960e-04 -4.498272e-04 -4.696324e-04
## ASV0649     -1.269590e-04 -1.327660e-04 -1.388264e-04 -1.451501e-04
## ASV1591     -9.351732e-06 -1.018706e-05 -1.109353e-05 -1.207674e-05
## ASV1854      4.317255e-04  4.518566e-04  4.729045e-04  4.949088e-04
## ASV4205      2.878934e-04  3.013204e-04  3.153596e-04  3.300376e-04
## ASV3293     -1.649379e-04 -1.722322e-04 -1.798240e-04 -1.877235e-04
## ASV1631      1.947797e-04  2.036351e-04  2.128749e-04  2.225141e-04
## ASV1747     -1.118293e-04 -1.172098e-04 -1.228501e-04 -1.287625e-04
## ASV5634      8.818336e-05  9.217621e-05  9.634120e-05  1.006850e-04
## ASV0965     -1.386093e-04 -1.448173e-04 -1.512860e-04 -1.580248e-04
## ASV1094      2.392250e-04  2.499497e-04  2.611258e-04  2.727697e-04
## ASV2744     -9.525282e-06 -1.037553e-05 -1.129810e-05 -1.229869e-05
## ASV7212     -3.643703e-04 -3.812183e-04 -3.988191e-04 -4.172035e-04
## ASV0344     -2.407138e-04 -2.516488e-04 -2.630564e-04 -2.749549e-04
## ASV11812    -2.611993e-04 -2.732099e-04 -2.857516e-04 -2.988457e-04
## ASV7867     -3.832778e-05 -4.021177e-05 -4.218924e-05 -4.426476e-05
## ASV6670      2.347091e-04  2.448252e-04  2.553317e-04  2.662401e-04
## ASV10991     2.145329e-06  1.609836e-06  9.957359e-07  2.953306e-07
## ASV1281      4.685750e-04  4.906133e-04  5.136726e-04  5.377987e-04
## ASV12845    -2.611768e-04 -2.731852e-04 -2.857245e-04 -2.988160e-04
## ASV1833     -2.611511e-04 -2.731571e-04 -2.856937e-04 -2.987823e-04
## ASV2211      1.678816e-04  1.750961e-04  1.825861e-04  1.903592e-04
## ASV3920      3.654747e-04  3.816359e-04  3.984546e-04  4.159527e-04
## ASV4545     -2.968215e-04 -3.104960e-04 -3.247775e-04 -3.396910e-04
## ASV4710     -3.239378e-04 -3.388175e-04 -3.543540e-04 -3.705735e-04
## ASV4978      5.169439e-05  5.409381e-05  5.660166e-05  5.922255e-05
## ASV9630     -9.198164e-06 -9.653631e-06 -1.013196e-05 -1.063430e-05
## ASV9797     -1.058492e-05 -1.145366e-05 -1.239447e-05 -1.341311e-05
## ASV13469    -2.610819e-04 -2.730812e-04 -2.856106e-04 -2.986913e-04
## ASV14961    -9.522973e-05 -9.959078e-05 -1.041428e-04 -1.088934e-04
## ASV6259      1.454030e-04  1.517540e-04  1.583563e-04  1.652174e-04
## ASV6294     -1.859204e-04 -1.944720e-04 -2.034016e-04 -2.127246e-04
## ASV6883     -8.765444e-05 -9.182767e-05 -9.619779e-05 -1.007738e-04
## ASV7041     -2.166048e-04 -2.267882e-04 -2.374412e-04 -2.485842e-04
## ASV4363     -2.514902e-04 -2.626243e-04 -2.742138e-04 -2.862739e-04
## ASV1784     -3.680746e-04 -3.847732e-04 -4.021914e-04 -4.203568e-04
## ASV2140      3.303247e-05  3.459770e-05  3.623513e-05  3.794778e-05
## ASV3202      2.514513e-04  2.625819e-04  2.741675e-04  2.862234e-04
## ASV6017     -2.514274e-04 -2.625559e-04 -2.741391e-04 -2.861925e-04
## ASV9129      1.259962e-04  1.314564e-04  1.371283e-04  1.430177e-04
## ASV0917      2.579768e-04  2.694151e-04  2.813228e-04  2.937159e-04
## ASV10584    -2.393394e-06 -2.160865e-06 -1.889029e-06 -1.573991e-06
## ASV11218     1.631491e-04  1.702483e-04  1.776255e-04  1.852890e-04
## ASV11229     2.525984e-05  2.674209e-05  2.831698e-05  2.999040e-05
## ASV11604    -2.956758e-05 -3.106772e-05 -3.264652e-05 -3.430818e-05
## ASV2103     -2.958767e-04 -3.091300e-04 -3.229400e-04 -3.373267e-04
## ASV2165     -2.513604e-04 -2.624828e-04 -2.740595e-04 -2.861057e-04
## ASV2340      2.774320e-04  2.892735e-04  3.015592e-04  3.143007e-04
## ASV3738     -2.513326e-04 -2.624524e-04 -2.740264e-04 -2.860697e-04
## ASV4012      7.626891e-05  7.963528e-05  8.313779e-05  8.678083e-05
## ASV4094     -2.513126e-04 -2.624307e-04 -2.740027e-04 -2.860439e-04
## ASV4454     -2.512888e-04 -2.624047e-04 -2.739744e-04 -2.860130e-04
## ASV7031      6.049303e-05  6.343821e-05  6.652830e-05  6.977041e-05
## ASV7087     -9.508496e-05 -9.905241e-05 -1.031608e-04 -1.074130e-04
## ASV4159      1.453120e-05  1.510926e-05  1.570464e-05  1.631731e-05
## ASV5084     -2.512621e-04 -2.623757e-04 -2.739428e-04 -2.859788e-04
## ASV6584     -2.512383e-04 -2.623497e-04 -2.739145e-04 -2.859479e-04
## ASV9614     -2.512145e-04 -2.623238e-04 -2.738862e-04 -2.859171e-04
## ASV16068    -2.511907e-04 -2.622978e-04 -2.738580e-04 -2.858863e-04
## ASV2141     -3.318917e-04 -3.460259e-04 -3.606922e-04 -3.759052e-04
## ASV0395     -2.407804e-05 -2.525499e-05 -2.649091e-05 -2.778888e-05
## ASV5640     -5.948351e-05 -6.235120e-05 -6.535683e-05 -6.850686e-05
## ASV2854     -2.821065e-04 -2.944823e-04 -3.073546e-04 -3.207396e-04
## ASV3825     -4.995994e-04 -5.221379e-04 -5.456368e-04 -5.701322e-04
## ASV0481      5.414905e-04  5.651775e-04  5.898104e-04  6.154194e-04
## ASV3304      2.564351e-05  2.685924e-05  2.813254e-05  2.946613e-05
## ASV0445      3.307886e-04  3.455668e-04  3.609611e-04  3.769933e-04
## ASV1845     -1.751683e-04 -1.833374e-04 -1.918782e-04 -2.008064e-04
## ASV3110     -1.916778e-04 -2.002521e-04 -2.091883e-04 -2.185004e-04

Stats::glm - Client needs p-values for each bacteria

3226

R documentation: https://www.rdocumentation.org/packages/stats/versions/3.6.2/topics/glm

278 x 3226 ASVs

library(stats)

logreg <- stats::glm(as.factor(Clade) ~ . ,
                     data = lr_clr_df[,-1],
                     family = "binomial")
summary(logreg)
## 
## Call:
## stats::glm(formula = as.factor(Clade) ~ ., family = "binomial", 
##     data = lr_clr_df[, -1])
## 
## Coefficients: (2949 not defined because of singularities)
##               Estimate Std. Error    z value Pr(>|z|)    
## (Intercept) -2.880e+31  4.028e+22 -7.149e+08   <2e-16 ***
## ASV1236     -4.149e+34  1.535e+38  0.000e+00    1.000    
## ASV0421     -7.219e+33  1.502e+37  0.000e+00    1.000    
## ASV0691     -1.816e+35  4.601e+38  0.000e+00    1.000    
## ASV0899      2.866e+34  6.424e+37  0.000e+00    1.000    
## ASV1004      8.578e+32  1.052e+37  0.000e+00    1.000    
## ASV1041      3.840e+34  6.224e+37  1.000e-03    1.000    
## ASV1058      6.163e+34  1.644e+38  0.000e+00    1.000    
## ASV12542    -9.556e+34  1.808e+38 -1.000e-03    1.000    
## ASV1294      5.553e+34  1.377e+38  0.000e+00    1.000    
## ASV13113     1.161e+33  4.798e+36  0.000e+00    1.000    
## ASV1318      1.158e+34  1.613e+37  1.000e-03    0.999    
## ASV2269      1.568e+35  3.485e+38  0.000e+00    1.000    
## ASV2542     -8.830e+32  1.637e+36 -1.000e-03    1.000    
## ASV2660     -1.285e+35  3.058e+38  0.000e+00    1.000    
## ASV2737     -5.775e+34  1.922e+38  0.000e+00    1.000    
## ASV2840      1.919e+33  6.876e+36  0.000e+00    1.000    
## ASV3053      1.422e+34  2.018e+38  0.000e+00    1.000    
## ASV3077     -1.166e+35  3.957e+38  0.000e+00    1.000    
## ASV3134     -8.330e+31  3.634e+36  0.000e+00    1.000    
## ASV3140     -1.154e+34  1.880e+37 -1.000e-03    1.000    
## ASV3579     -6.390e+33  1.505e+37  0.000e+00    1.000    
## ASV6119             NA         NA         NA       NA    
## ASV7557             NA         NA         NA       NA    
## ASV8422             NA         NA         NA       NA    
## ASV1086             NA         NA         NA       NA    
## ASV1310      2.802e+34  3.158e+37  1.000e-03    0.999    
## ASV15750     1.307e+35  3.444e+38  0.000e+00    1.000    
## ASV16905            NA         NA         NA       NA    
## ASV2033     -1.608e+34  1.242e+37 -1.000e-03    0.999    
## ASV2089             NA         NA         NA       NA    
## ASV2127     -1.090e+34  4.184e+37  0.000e+00    1.000    
## ASV2725      2.892e+34  8.052e+37  0.000e+00    1.000    
## ASV2804             NA         NA         NA       NA    
## ASV3075      1.043e+34  2.681e+37  0.000e+00    1.000    
## ASV3327      2.417e+34  9.291e+37  0.000e+00    1.000    
## ASV3342     -9.806e+33  3.121e+37  0.000e+00    1.000    
## ASV3532     -1.473e+34  3.186e+37  0.000e+00    1.000    
## ASV3600     -7.428e+33  1.552e+37  0.000e+00    1.000    
## ASV4013      2.677e+34  2.153e+37  1.000e-03    0.999    
## ASV4136     -2.299e+34  8.747e+37  0.000e+00    1.000    
## ASV4195             NA         NA         NA       NA    
## ASV4407             NA         NA         NA       NA    
## ASV4717             NA         NA         NA       NA    
## ASV6794             NA         NA         NA       NA    
## ASV8324             NA         NA         NA       NA    
## ASV8981     -4.567e+33  1.680e+37  0.000e+00    1.000    
## ASV9859     -2.192e+33  2.132e+37  0.000e+00    1.000    
## ASV0936      1.234e+34  1.426e+37  1.000e-03    0.999    
## ASV12683            NA         NA         NA       NA    
## ASV1293      1.416e+34  3.309e+37  0.000e+00    1.000    
## ASV13055            NA         NA         NA       NA    
## ASV17063            NA         NA         NA       NA    
## ASV2228             NA         NA         NA       NA    
## ASV2769     -7.899e+34  1.269e+38 -1.000e-03    1.000    
## ASV2803     -8.155e+33  8.833e+37  0.000e+00    1.000    
## ASV2896     -1.485e+33  2.748e+36 -1.000e-03    1.000    
## ASV3062             NA         NA         NA       NA    
## ASV3107     -4.028e+31  1.982e+36  0.000e+00    1.000    
## ASV3265     -5.383e+31  2.193e+37  0.000e+00    1.000    
## ASV3666             NA         NA         NA       NA    
## ASV4497      9.538e+34  2.124e+38  0.000e+00    1.000    
## ASV6914             NA         NA         NA       NA    
## ASV0576      1.539e+35  3.360e+38  0.000e+00    1.000    
## ASV0673     -6.677e+34  1.355e+38  0.000e+00    1.000    
## ASV0772     -6.733e+34  7.108e+37 -1.000e-03    0.999    
## ASV0862             NA         NA         NA       NA    
## ASV0898             NA         NA         NA       NA    
## ASV0910     -4.105e+33  4.223e+36 -1.000e-03    0.999    
## ASV0964             NA         NA         NA       NA    
## ASV10059    -9.224e+32  5.249e+35 -2.000e-03    0.999    
## ASV10263            NA         NA         NA       NA    
## ASV1088     -9.203e+33  9.383e+36 -1.000e-03    0.999    
## ASV1101             NA         NA         NA       NA    
## ASV1183      8.080e+33  2.922e+37  0.000e+00    1.000    
## ASV11956            NA         NA         NA       NA    
## ASV12774            NA         NA         NA       NA    
## ASV1321             NA         NA         NA       NA    
## ASV13793            NA         NA         NA       NA    
## ASV14482            NA         NA         NA       NA    
## ASV15483            NA         NA         NA       NA    
## ASV2062             NA         NA         NA       NA    
## ASV2132      2.636e+33  7.287e+36  0.000e+00    1.000    
## ASV2413             NA         NA         NA       NA    
## ASV2490             NA         NA         NA       NA    
## ASV2594     -3.671e+33  3.510e+36 -1.000e-03    0.999    
## ASV2822             NA         NA         NA       NA    
## ASV2863             NA         NA         NA       NA    
## ASV2910             NA         NA         NA       NA    
## ASV2980     -1.018e+34  1.300e+37 -1.000e-03    0.999    
## ASV3307             NA         NA         NA       NA    
## ASV3474             NA         NA         NA       NA    
## ASV3502      1.174e+33  3.275e+37  0.000e+00    1.000    
## ASV4236             NA         NA         NA       NA    
## ASV4842             NA         NA         NA       NA    
## ASV4894             NA         NA         NA       NA    
## ASV5290             NA         NA         NA       NA    
## ASV5501      6.076e+33  5.417e+37  0.000e+00    1.000    
## ASV5795             NA         NA         NA       NA    
## ASV5987             NA         NA         NA       NA    
## ASV6267             NA         NA         NA       NA    
## ASV6862             NA         NA         NA       NA    
## ASV7145             NA         NA         NA       NA    
## ASV7673             NA         NA         NA       NA    
## ASV7789             NA         NA         NA       NA    
## ASV7809             NA         NA         NA       NA    
## ASV8002             NA         NA         NA       NA    
## ASV8205      1.721e+33  1.992e+36  1.000e-03    0.999    
## ASV9155             NA         NA         NA       NA    
## ASV9221     -4.034e+33  1.323e+37  0.000e+00    1.000    
## ASV9311             NA         NA         NA       NA    
## ASV9557             NA         NA         NA       NA    
## ASV9936             NA         NA         NA       NA    
## ASV1445      3.537e+33  1.047e+37  0.000e+00    1.000    
## ASV4232      2.474e+32  5.699e+36  0.000e+00    1.000    
## ASV6479     -3.591e+33  1.755e+37  0.000e+00    1.000    
## ASV0142     -6.407e+34  8.205e+37 -1.000e-03    0.999    
## ASV0378      4.944e+33  2.274e+37  0.000e+00    1.000    
## ASV1122      9.844e+33  5.743e+36  2.000e-03    0.999    
## ASV0123      1.174e+35  2.298e+38  1.000e-03    1.000    
## ASV2064      2.971e+34  2.632e+37  1.000e-03    0.999    
## ASV4459     -4.566e+33  3.147e+37  0.000e+00    1.000    
## ASV0448      8.855e+32  4.021e+36  0.000e+00    1.000    
## ASV0397      5.454e+33  3.225e+36  2.000e-03    0.999    
## ASV0485     -6.123e+32  8.358e+35 -1.000e-03    0.999    
## ASV1566             NA         NA         NA       NA    
## ASV1365      1.345e+34  1.281e+37  1.000e-03    0.999    
## ASV1065     -6.132e+33  1.217e+37 -1.000e-03    1.000    
## ASV0722      1.223e+34  5.077e+37  0.000e+00    1.000    
## ASV12660            NA         NA         NA       NA    
## ASV0223      9.326e+31  2.937e+36  0.000e+00    1.000    
## ASV0229      2.406e+32  2.545e+37  0.000e+00    1.000    
## ASV0877      1.559e+34  2.751e+37  1.000e-03    1.000    
## ASV0983      3.222e+33  4.074e+37  0.000e+00    1.000    
## ASV0626             NA         NA         NA       NA    
## ASV4146      1.191e+33  1.873e+37  0.000e+00    1.000    
## ASV4175     -1.192e+34  6.769e+37  0.000e+00    1.000    
## ASV2082     -1.738e+33  4.065e+37  0.000e+00    1.000    
## ASV2272      1.819e+33  2.927e+36  1.000e-03    1.000    
## ASV2245      4.247e+34  1.112e+38  0.000e+00    1.000    
## ASV0590             NA         NA         NA       NA    
## ASV0217      9.857e+33  1.205e+37  1.000e-03    0.999    
## ASV0416     -5.675e+33  5.779e+36 -1.000e-03    0.999    
## ASV1056     -6.651e+33  1.592e+37  0.000e+00    1.000    
## ASV7777      1.979e+32  3.526e+35  1.000e-03    1.000    
## ASV0455      1.312e+33  1.582e+36  1.000e-03    0.999    
## ASV0604             NA         NA         NA       NA    
## ASV6100      5.758e+32  1.493e+36  0.000e+00    1.000    
## ASV11359    -1.696e+34  2.293e+37 -1.000e-03    0.999    
## ASV6604      8.731e+33  2.177e+37  0.000e+00    1.000    
## ASV5004     -5.365e+33  2.712e+37  0.000e+00    1.000    
## ASV1483      6.759e+33  2.523e+37  0.000e+00    1.000    
## ASV9773     -2.517e+32  8.033e+35  0.000e+00    1.000    
## ASV4059      3.719e+33  7.644e+36  0.000e+00    1.000    
## ASV1193      2.993e+32  6.384e+36  0.000e+00    1.000    
## ASV4610             NA         NA         NA       NA    
## ASV0742             NA         NA         NA       NA    
## ASV1502     -1.217e+34  3.605e+37  0.000e+00    1.000    
## ASV0195      3.770e+33  1.284e+37  0.000e+00    1.000    
## ASV1213      1.528e+34  3.933e+37  0.000e+00    1.000    
## ASV1648     -3.924e+33  1.206e+37  0.000e+00    1.000    
## ASV6984     -1.787e+33  3.578e+36  0.000e+00    1.000    
## ASV0396     -6.942e+33  4.986e+36 -1.000e-03    0.999    
## ASV4297             NA         NA         NA       NA    
## ASV2622     -4.331e+33  1.160e+37  0.000e+00    1.000    
## ASV3512      1.858e+33  7.366e+36  0.000e+00    1.000    
## ASV2411             NA         NA         NA       NA    
## ASV2291             NA         NA         NA       NA    
## ASV0807     -4.121e+33  3.065e+36 -1.000e-03    0.999    
## ASV1292      6.169e+33  2.642e+37  0.000e+00    1.000    
## ASV1035             NA         NA         NA       NA    
## ASV0070     -2.231e+33  3.194e+36 -1.000e-03    0.999    
## ASV0255      5.166e+32  1.279e+37  0.000e+00    1.000    
## ASV0057      1.611e+33  3.419e+36  0.000e+00    1.000    
## ASV0077     -9.392e+32  9.182e+35 -1.000e-03    0.999    
## ASV0625      6.430e+33  2.133e+37  0.000e+00    1.000    
## ASV2464             NA         NA         NA       NA    
## ASV1315      1.155e+34  3.160e+37  0.000e+00    1.000    
## ASV2673      1.270e+33  3.223e+36  0.000e+00    1.000    
## ASV2161     -1.158e+34  3.815e+37  0.000e+00    1.000    
## ASV0337      7.970e+33  2.902e+37  0.000e+00    1.000    
## ASV7680     -2.264e+33  9.480e+36  0.000e+00    1.000    
## ASV0611     -9.620e+32  5.105e+35 -2.000e-03    0.998    
## ASV3118     -4.495e+33  2.661e+37  0.000e+00    1.000    
## ASV1284      3.493e+33  1.980e+37  0.000e+00    1.000    
## ASV0889             NA         NA         NA       NA    
## ASV4649     -1.280e+34  3.889e+37  0.000e+00    1.000    
## ASV1108      1.812e+32  3.438e+36  0.000e+00    1.000    
## ASV0738     -4.827e+33  1.311e+37  0.000e+00    1.000    
## ASV0473     -4.647e+32  5.244e+36  0.000e+00    1.000    
## ASV0598             NA         NA         NA       NA    
## ASV0429      1.390e+34  3.535e+37  0.000e+00    1.000    
## ASV1549     -1.292e+33  7.928e+36  0.000e+00    1.000    
## ASV1203      3.030e+33  9.238e+36  0.000e+00    1.000    
## ASV4532      5.620e+33  5.879e+36  1.000e-03    0.999    
## ASV0274      6.311e+33  5.906e+36  1.000e-03    0.999    
## ASV0163      9.020e+33  2.429e+37  0.000e+00    1.000    
## ASV1298     -1.716e+33  2.629e+36 -1.000e-03    0.999    
## ASV9424      1.117e+34  3.245e+37  0.000e+00    1.000    
## ASV0412      1.676e+33  1.091e+37  0.000e+00    1.000    
## ASV0284     -2.095e+33  1.114e+37  0.000e+00    1.000    
## ASV0620             NA         NA         NA       NA    
## ASV0153     -1.081e+33  2.380e+36  0.000e+00    1.000    
## ASV0498      2.773e+32  3.417e+36  0.000e+00    1.000    
## ASV0097     -1.844e+32  9.372e+36  0.000e+00    1.000    
## ASV0104      9.679e+32  1.261e+37  0.000e+00    1.000    
## ASV1282      2.504e+33  2.191e+37  0.000e+00    1.000    
## ASV3883     -1.801e+33  1.147e+37  0.000e+00    1.000    
## ASV0801      1.600e+33  6.103e+36  0.000e+00    1.000    
## ASV1611      4.351e+33  2.600e+37  0.000e+00    1.000    
## ASV0227      2.934e+33  1.486e+37  0.000e+00    1.000    
## ASV0833             NA         NA         NA       NA    
## ASV0718      2.498e+33  1.003e+37  0.000e+00    1.000    
## ASV1139             NA         NA         NA       NA    
## ASV0766     -1.056e+34  2.123e+37  0.000e+00    1.000    
## ASV2091     -5.558e+33  3.367e+37  0.000e+00    1.000    
## ASV1238      8.848e+33  1.400e+37  1.000e-03    0.999    
## ASV9193             NA         NA         NA       NA    
## ASV0290     -9.339e+33  3.123e+37  0.000e+00    1.000    
## ASV0231     -2.711e+33  6.415e+36  0.000e+00    1.000    
## ASV0185      2.305e+32  5.670e+35  0.000e+00    1.000    
## ASV2330             NA         NA         NA       NA    
## ASV3119      1.692e+33  1.477e+36  1.000e-03    0.999    
## ASV2368      2.026e+32  6.353e+35  0.000e+00    1.000    
## ASV0122     -4.592e+33  7.572e+36 -1.000e-03    1.000    
## ASV1044     -1.369e+33  2.475e+36 -1.000e-03    1.000    
## ASV0160     -1.445e+33  3.484e+36  0.000e+00    1.000    
## ASV0326     -1.080e+33  3.289e+36  0.000e+00    1.000    
## ASV1388      2.024e+33  2.040e+36  1.000e-03    0.999    
## ASV0792             NA         NA         NA       NA    
## ASV0036     -3.690e+33  1.838e+36 -2.000e-03    0.998    
## ASV2125     -3.618e+32  3.351e+36  0.000e+00    1.000    
## ASV1075      3.311e+33  3.863e+36  1.000e-03    0.999    
## ASV0390     -3.747e+32  1.204e+36  0.000e+00    1.000    
## ASV3790      1.588e+33  5.729e+36  0.000e+00    1.000    
## ASV1535     -6.395e+33  1.860e+37  0.000e+00    1.000    
## ASV0263             NA         NA         NA       NA    
## ASV0675     -5.435e+32  5.894e+36  0.000e+00    1.000    
## ASV3348     -2.178e+33  6.196e+36  0.000e+00    1.000    
## ASV0058     -1.205e+33  1.569e+36 -1.000e-03    0.999    
## ASV4142             NA         NA         NA       NA    
## ASV0059      7.130e+32  8.228e+35  1.000e-03    0.999    
## ASV0013     -7.786e+32  1.535e+37  0.000e+00    1.000    
## ASV0033      5.192e+33  8.043e+36  1.000e-03    0.999    
## ASV4354             NA         NA         NA       NA    
## ASV0022     -1.866e+33  1.244e+37  0.000e+00    1.000    
## ASV0134      6.838e+32  2.711e+36  0.000e+00    1.000    
## ASV0415     -2.899e+33  9.763e+36  0.000e+00    1.000    
## ASV10103            NA         NA         NA       NA    
## ASV1613     -2.181e+32  5.743e+36  0.000e+00    1.000    
## ASV0135      1.180e+31  4.180e+35  0.000e+00    1.000    
## ASV0469             NA         NA         NA       NA    
## ASV0471     -3.078e+33  1.214e+37  0.000e+00    1.000    
## ASV0451      8.272e+32  3.247e+36  0.000e+00    1.000    
## ASV0747      2.441e+32  8.929e+35  0.000e+00    1.000    
## ASV1314     -3.204e+33  1.057e+37  0.000e+00    1.000    
## ASV0425             NA         NA         NA       NA    
## ASV0559     -1.133e+34  2.062e+37 -1.000e-03    1.000    
## ASV0148      2.372e+33  6.980e+36  0.000e+00    1.000    
## ASV0129     -1.963e+33  6.923e+36  0.000e+00    1.000    
## ASV1072     -5.392e+33  1.062e+37 -1.000e-03    1.000    
## ASV2390             NA         NA         NA       NA    
## ASV0548     -4.313e+33  7.294e+36 -1.000e-03    1.000    
## ASV0168     -5.128e+32  4.090e+35 -1.000e-03    0.999    
## ASV0066      1.635e+32  1.353e+36  0.000e+00    1.000    
## ASV0468      1.984e+33  7.011e+36  0.000e+00    1.000    
## ASV0172      8.945e+32  1.315e+36  1.000e-03    0.999    
## ASV0236     -2.539e+32  4.912e+36  0.000e+00    1.000    
## ASV0250     -1.591e+33  7.658e+36  0.000e+00    1.000    
## ASV0338      2.069e+33  1.067e+37  0.000e+00    1.000    
## ASV0450     -6.260e+33  1.353e+37  0.000e+00    1.000    
## ASV0377             NA         NA         NA       NA    
## ASV1022     -1.757e+32  5.718e+35  0.000e+00    1.000    
## ASV6174             NA         NA         NA       NA    
## ASV0786             NA         NA         NA       NA    
## ASV0053     -2.458e+32  6.897e+35  0.000e+00    1.000    
## ASV0697      5.065e+32  6.094e+36  0.000e+00    1.000    
## ASV0785     -1.641e+33  5.283e+36  0.000e+00    1.000    
## ASV1967     -6.916e+33  1.717e+37  0.000e+00    1.000    
## ASV0385     -1.327e+32  1.278e+36  0.000e+00    1.000    
## ASV0295      2.275e+32  7.441e+35  0.000e+00    1.000    
## ASV0072      1.094e+33  6.490e+35  2.000e-03    0.999    
## ASV0157      1.506e+33  3.159e+36  0.000e+00    1.000    
## ASV0501     -6.608e+33  6.836e+36 -1.000e-03    0.999    
## ASV10729    -1.330e+33  1.838e+36 -1.000e-03    0.999    
## ASV1470             NA         NA         NA       NA    
## ASV0050     -2.124e+33  2.917e+37  0.000e+00    1.000    
## ASV0411     -4.211e+32  5.668e+36  0.000e+00    1.000    
## ASV0549      8.365e+32  9.417e+36  0.000e+00    1.000    
## ASV0184      3.552e+30  3.283e+33  1.000e-03    0.999    
## ASV0705     -1.760e+33  8.082e+36  0.000e+00    1.000    
## ASV1715     -1.248e+33  6.190e+36  0.000e+00    1.000    
## ASV0603     -9.083e+32  1.139e+37  0.000e+00    1.000    
## ASV0826             NA         NA         NA       NA    
## ASV0034     -1.386e+33  1.969e+36 -1.000e-03    0.999    
## ASV0838      2.176e+33  6.071e+36  0.000e+00    1.000    
## ASV0614     -7.819e+30  4.586e+36  0.000e+00    1.000    
## ASV0014     -5.161e+33  1.300e+37  0.000e+00    1.000    
## ASV0585             NA         NA         NA       NA    
## ASV0016      3.864e+33  1.236e+37  0.000e+00    1.000    
## ASV5394      4.902e+31  4.740e+35  0.000e+00    1.000    
## ASV0666             NA         NA         NA       NA    
## ASV2085             NA         NA         NA       NA    
## ASV0003      3.287e+33  3.029e+37  0.000e+00    1.000    
## ASV0346      9.616e+32  7.383e+36  0.000e+00    1.000    
## ASV0267     -1.085e+33  2.773e+36  0.000e+00    1.000    
## ASV0353      1.676e+33  8.754e+35  2.000e-03    0.998    
## ASV2419     -2.316e+33  5.407e+36  0.000e+00    1.000    
## ASV0447             NA         NA         NA       NA    
## ASV0654             NA         NA         NA       NA    
## ASV0151     -2.449e+33  6.167e+36  0.000e+00    1.000    
## ASV0065      1.032e+33  1.086e+36  1.000e-03    0.999    
## ASV0527      6.130e+32  3.240e+36  0.000e+00    1.000    
## ASV4055             NA         NA         NA       NA    
## ASV0166             NA         NA         NA       NA    
## ASV0417     -6.496e+32  5.489e+35 -1.000e-03    0.999    
## ASV0078      7.887e+31  3.304e+36  0.000e+00    1.000    
## ASV0322             NA         NA         NA       NA    
## ASV0156     -2.074e+33  3.486e+36 -1.000e-03    1.000    
## ASV0648             NA         NA         NA       NA    
## ASV0407     -1.864e+32  1.218e+36  0.000e+00    1.000    
## ASV2030             NA         NA         NA       NA    
## ASV0300      9.106e+32  2.310e+36  0.000e+00    1.000    
## ASV1150     -2.376e+32  3.940e+36  0.000e+00    1.000    
## ASV0958     -2.550e+32  1.401e+36  0.000e+00    1.000    
## ASV0216             NA         NA         NA       NA    
## ASV0446      4.933e+32  2.747e+36  0.000e+00    1.000    
## ASV0367             NA         NA         NA       NA    
## ASV0200             NA         NA         NA       NA    
## ASV0334             NA         NA         NA       NA    
## ASV1311             NA         NA         NA       NA    
## ASV0458             NA         NA         NA       NA    
## ASV1371             NA         NA         NA       NA    
## ASV0418             NA         NA         NA       NA    
## ASV0004      1.822e+32  7.542e+36  0.000e+00    1.000    
## ASV1943             NA         NA         NA       NA    
## ASV1495     -3.254e+31  3.057e+35  0.000e+00    1.000    
## ASV0901             NA         NA         NA       NA    
## ASV0628             NA         NA         NA       NA    
## ASV0400             NA         NA         NA       NA    
## ASV0116             NA         NA         NA       NA    
## ASV0788     -3.770e+33  4.419e+36 -1.000e-03    0.999    
## ASV0117      1.331e+31  1.230e+36  0.000e+00    1.000    
## ASV3137             NA         NA         NA       NA    
## ASV0001             NA         NA         NA       NA    
## ASV1651     -4.041e+32  6.179e+35 -1.000e-03    0.999    
## ASV1692             NA         NA         NA       NA    
## ASV0660             NA         NA         NA       NA    
## ASV0508             NA         NA         NA       NA    
## ASV1660             NA         NA         NA       NA    
## ASV0233             NA         NA         NA       NA    
## ASV1343             NA         NA         NA       NA    
## ASV0209             NA         NA         NA       NA    
## ASV0193             NA         NA         NA       NA    
## ASV0357     -3.118e+33  1.580e+37  0.000e+00    1.000    
## ASV0198             NA         NA         NA       NA    
## ASV0007             NA         NA         NA       NA    
## ASV1772             NA         NA         NA       NA    
## ASV0009             NA         NA         NA       NA    
## ASV0006             NA         NA         NA       NA    
## ASV0011             NA         NA         NA       NA    
## ASV0015             NA         NA         NA       NA    
## ASV0017             NA         NA         NA       NA    
## ASV0235             NA         NA         NA       NA    
## ASV0382     -7.891e+32  2.685e+36  0.000e+00    1.000    
## ASV2357             NA         NA         NA       NA    
## ASV0567             NA         NA         NA       NA    
## ASV0165             NA         NA         NA       NA    
## ASV0005             NA         NA         NA       NA    
## ASV0384             NA         NA         NA       NA    
## ASV0002             NA         NA         NA       NA    
## ASV3017             NA         NA         NA       NA    
## ASV0091      1.698e+33  1.597e+36  1.000e-03    0.999    
## ASV0186             NA         NA         NA       NA    
## ASV0370             NA         NA         NA       NA    
## ASV0018             NA         NA         NA       NA    
## ASV1377             NA         NA         NA       NA    
## ASV0019             NA         NA         NA       NA    
## ASV0023             NA         NA         NA       NA    
## ASV2194             NA         NA         NA       NA    
## ASV1155             NA         NA         NA       NA    
## ASV0510             NA         NA         NA       NA    
## ASV2371             NA         NA         NA       NA    
## ASV0024             NA         NA         NA       NA    
## ASV2452             NA         NA         NA       NA    
## ASV2332             NA         NA         NA       NA    
## ASV2591             NA         NA         NA       NA    
## ASV0521             NA         NA         NA       NA    
## ASV5542             NA         NA         NA       NA    
## ASV0336             NA         NA         NA       NA    
## ASV10102            NA         NA         NA       NA    
## ASV16823            NA         NA         NA       NA    
## ASV3104             NA         NA         NA       NA    
## ASV0781             NA         NA         NA       NA    
## ASV10899            NA         NA         NA       NA    
## ASV11222            NA         NA         NA       NA    
## ASV11327            NA         NA         NA       NA    
## ASV12458            NA         NA         NA       NA    
## ASV1636             NA         NA         NA       NA    
## ASV1890             NA         NA         NA       NA    
## ASV2898             NA         NA         NA       NA    
## ASV8328             NA         NA         NA       NA    
## ASV0709             NA         NA         NA       NA    
## ASV0856             NA         NA         NA       NA    
## ASV0909             NA         NA         NA       NA    
## ASV0937             NA         NA         NA       NA    
## ASV11390            NA         NA         NA       NA    
## ASV11966            NA         NA         NA       NA    
## ASV12990            NA         NA         NA       NA    
## ASV14797            NA         NA         NA       NA    
## ASV14904            NA         NA         NA       NA    
## ASV15304            NA         NA         NA       NA    
## ASV16696            NA         NA         NA       NA    
## ASV1690             NA         NA         NA       NA    
## ASV2029             NA         NA         NA       NA    
## ASV2834             NA         NA         NA       NA    
## ASV4003             NA         NA         NA       NA    
## ASV4064             NA         NA         NA       NA    
## ASV4294             NA         NA         NA       NA    
## ASV4609             NA         NA         NA       NA    
## ASV6283             NA         NA         NA       NA    
## ASV6491             NA         NA         NA       NA    
## ASV7453             NA         NA         NA       NA    
## ASV7959             NA         NA         NA       NA    
## ASV8219             NA         NA         NA       NA    
## ASV8547             NA         NA         NA       NA    
## ASV9319             NA         NA         NA       NA    
## ASV9382             NA         NA         NA       NA    
## ASV11516            NA         NA         NA       NA    
## ASV14377            NA         NA         NA       NA    
## ASV1867             NA         NA         NA       NA    
## ASV1895             NA         NA         NA       NA    
## ASV3168             NA         NA         NA       NA    
## ASV4449             NA         NA         NA       NA    
## ASV6596             NA         NA         NA       NA    
## ASV7492             NA         NA         NA       NA    
## ASV9854             NA         NA         NA       NA    
## ASV6296             NA         NA         NA       NA    
## ASV4201             NA         NA         NA       NA    
## ASV0552             NA         NA         NA       NA    
## ASV3671             NA         NA         NA       NA    
## ASV3529             NA         NA         NA       NA    
## ASV1060             NA         NA         NA       NA    
## ASV0239             NA         NA         NA       NA    
## ASV5711             NA         NA         NA       NA    
## ASV4152             NA         NA         NA       NA    
## ASV1461             NA         NA         NA       NA    
## ASV2877             NA         NA         NA       NA    
## ASV0012             NA         NA         NA       NA    
## ASV9823             NA         NA         NA       NA    
## ASV0008             NA         NA         NA       NA    
## ASV7832             NA         NA         NA       NA    
## ASV1915             NA         NA         NA       NA    
## ASV0055             NA         NA         NA       NA    
## ASV0032             NA         NA         NA       NA    
## ASV2977             NA         NA         NA       NA    
## ASV0466             NA         NA         NA       NA    
## ASV3866             NA         NA         NA       NA    
## ASV0040             NA         NA         NA       NA    
## ASV0496             NA         NA         NA       NA    
## ASV0052             NA         NA         NA       NA    
## ASV3828             NA         NA         NA       NA    
## ASV1930             NA         NA         NA       NA    
## ASV2126             NA         NA         NA       NA    
## ASV0793             NA         NA         NA       NA    
## ASV0299             NA         NA         NA       NA    
## ASV0208             NA         NA         NA       NA    
## ASV0511             NA         NA         NA       NA    
## ASV1123             NA         NA         NA       NA    
## ASV0099             NA         NA         NA       NA    
## ASV0752             NA         NA         NA       NA    
## ASV0883             NA         NA         NA       NA    
## ASV0683             NA         NA         NA       NA    
## ASV4117             NA         NA         NA       NA    
## ASV2172             NA         NA         NA       NA    
## ASV0330             NA         NA         NA       NA    
## ASV0728             NA         NA         NA       NA    
## ASV0499             NA         NA         NA       NA    
## ASV0120             NA         NA         NA       NA    
## ASV1446             NA         NA         NA       NA    
## ASV17171            NA         NA         NA       NA    
## ASV0533             NA         NA         NA       NA    
## ASV2495             NA         NA         NA       NA    
## ASV5582             NA         NA         NA       NA    
## ASV1488             NA         NA         NA       NA    
## ASV0682             NA         NA         NA       NA    
## ASV0068             NA         NA         NA       NA    
## ASV1987             NA         NA         NA       NA    
## ASV0035             NA         NA         NA       NA    
## ASV7192             NA         NA         NA       NA    
## ASV0873             NA         NA         NA       NA    
## ASV4749             NA         NA         NA       NA    
## ASV2174             NA         NA         NA       NA    
## ASV1476             NA         NA         NA       NA    
## ASV0740             NA         NA         NA       NA    
## ASV0170             NA         NA         NA       NA    
## ASV2466             NA         NA         NA       NA    
## ASV1709             NA         NA         NA       NA    
## ASV6170             NA         NA         NA       NA    
## ASV3673             NA         NA         NA       NA    
## ASV1745             NA         NA         NA       NA    
## ASV0380      2.198e+33  9.375e+36  0.000e+00    1.000    
## ASV0426             NA         NA         NA       NA    
## ASV0202             NA         NA         NA       NA    
## ASV6350             NA         NA         NA       NA    
## ASV0713             NA         NA         NA       NA    
## ASV1822             NA         NA         NA       NA    
## ASV4569             NA         NA         NA       NA    
## ASV0030             NA         NA         NA       NA    
## ASV0331             NA         NA         NA       NA    
## ASV2981             NA         NA         NA       NA    
## ASV0828             NA         NA         NA       NA    
## ASV2440             NA         NA         NA       NA    
## ASV3006             NA         NA         NA       NA    
## ASV3875             NA         NA         NA       NA    
## ASV4511             NA         NA         NA       NA    
## ASV4700             NA         NA         NA       NA    
## ASV5804             NA         NA         NA       NA    
## ASV6826             NA         NA         NA       NA    
## ASV7280             NA         NA         NA       NA    
## ASV7535             NA         NA         NA       NA    
## ASV0651             NA         NA         NA       NA    
## ASV0913             NA         NA         NA       NA    
## ASV10832            NA         NA         NA       NA    
## ASV1117             NA         NA         NA       NA    
## ASV11329            NA         NA         NA       NA    
## ASV13209            NA         NA         NA       NA    
## ASV1345             NA         NA         NA       NA    
## ASV1719             NA         NA         NA       NA    
## ASV1886             NA         NA         NA       NA    
## ASV2158             NA         NA         NA       NA    
## ASV2189             NA         NA         NA       NA    
## ASV2257             NA         NA         NA       NA    
## ASV2283             NA         NA         NA       NA    
## ASV2328             NA         NA         NA       NA    
## ASV2434             NA         NA         NA       NA    
## ASV2648             NA         NA         NA       NA    
## ASV2698             NA         NA         NA       NA    
## ASV2775             NA         NA         NA       NA    
## ASV3171             NA         NA         NA       NA    
## ASV3227             NA         NA         NA       NA    
## ASV3397             NA         NA         NA       NA    
## ASV3444             NA         NA         NA       NA    
## ASV3556             NA         NA         NA       NA    
## ASV3606             NA         NA         NA       NA    
## ASV4190             NA         NA         NA       NA    
## ASV4197             NA         NA         NA       NA    
## ASV4722             NA         NA         NA       NA    
## ASV4765             NA         NA         NA       NA    
## ASV4809             NA         NA         NA       NA    
## ASV4846             NA         NA         NA       NA    
## ASV4903             NA         NA         NA       NA    
## ASV4944             NA         NA         NA       NA    
## ASV5151             NA         NA         NA       NA    
## ASV5413             NA         NA         NA       NA    
## ASV5537             NA         NA         NA       NA    
## ASV5688             NA         NA         NA       NA    
## ASV5752             NA         NA         NA       NA    
## ASV6122             NA         NA         NA       NA    
## ASV6135             NA         NA         NA       NA    
## ASV6188             NA         NA         NA       NA    
## ASV6216             NA         NA         NA       NA    
## ASV6242             NA         NA         NA       NA    
## ASV6383             NA         NA         NA       NA    
## ASV6781             NA         NA         NA       NA    
## ASV6799             NA         NA         NA       NA    
## ASV7374             NA         NA         NA       NA    
## ASV7539             NA         NA         NA       NA    
## ASV8591             NA         NA         NA       NA    
## ASV8637             NA         NA         NA       NA    
## ASV12796            NA         NA         NA       NA    
## ASV1934             NA         NA         NA       NA    
## ASV22549            NA         NA         NA       NA    
## ASV29857            NA         NA         NA       NA    
## ASV3215             NA         NA         NA       NA    
## ASV3236             NA         NA         NA       NA    
## ASV3954             NA         NA         NA       NA    
## ASV4850             NA         NA         NA       NA    
## ASV5225             NA         NA         NA       NA    
## ASV5532             NA         NA         NA       NA    
## ASV7258             NA         NA         NA       NA    
## ASV9474             NA         NA         NA       NA    
## ASV11857            NA         NA         NA       NA    
## ASV1202             NA         NA         NA       NA    
## ASV14742            NA         NA         NA       NA    
## ASV16652            NA         NA         NA       NA    
## ASV2019             NA         NA         NA       NA    
## ASV2410             NA         NA         NA       NA    
## ASV2718             NA         NA         NA       NA    
## ASV2738             NA         NA         NA       NA    
## ASV2876             NA         NA         NA       NA    
## ASV3177             NA         NA         NA       NA    
## ASV4367             NA         NA         NA       NA    
## ASV4635             NA         NA         NA       NA    
## ASV4896             NA         NA         NA       NA    
## ASV4907             NA         NA         NA       NA    
## ASV5230             NA         NA         NA       NA    
## ASV6509             NA         NA         NA       NA    
## ASV7376             NA         NA         NA       NA    
## ASV8163             NA         NA         NA       NA    
## ASV8195             NA         NA         NA       NA    
## ASV8923             NA         NA         NA       NA    
## ASV9666             NA         NA         NA       NA    
## ASV1482             NA         NA         NA       NA    
## ASV2726             NA         NA         NA       NA    
## ASV3281             NA         NA         NA       NA    
## ASV4235             NA         NA         NA       NA    
## ASV4808             NA         NA         NA       NA    
## ASV4861             NA         NA         NA       NA    
## ASV5276             NA         NA         NA       NA    
## ASV5837             NA         NA         NA       NA    
## ASV7098             NA         NA         NA       NA    
## ASV8451             NA         NA         NA       NA    
## ASV8694             NA         NA         NA       NA    
## ASV0905             NA         NA         NA       NA    
## ASV2900             NA         NA         NA       NA    
## ASV3963             NA         NA         NA       NA    
## ASV0041             NA         NA         NA       NA    
## ASV1865             NA         NA         NA       NA    
## ASV1140             NA         NA         NA       NA    
## ASV1179             NA         NA         NA       NA    
## ASV0279             NA         NA         NA       NA    
## ASV0043             NA         NA         NA       NA    
## ASV2097             NA         NA         NA       NA    
## ASV0309             NA         NA         NA       NA    
## ASV0607             NA         NA         NA       NA    
## ASV0025             NA         NA         NA       NA    
## ASV2284             NA         NA         NA       NA    
## ASV0556             NA         NA         NA       NA    
## ASV5040             NA         NA         NA       NA    
## ASV2924             NA         NA         NA       NA    
## ASV1331             NA         NA         NA       NA    
## ASV0506             NA         NA         NA       NA    
## ASV1514             NA         NA         NA       NA    
## ASV2144             NA         NA         NA       NA    
## ASV2265             NA         NA         NA       NA    
## ASV5156             NA         NA         NA       NA    
## ASV5534             NA         NA         NA       NA    
## ASV5747             NA         NA         NA       NA    
## ASV6657             NA         NA         NA       NA    
## ASV0658             NA         NA         NA       NA    
## ASV0716             NA         NA         NA       NA    
## ASV1657             NA         NA         NA       NA    
## ASV1885             NA         NA         NA       NA    
## ASV2333             NA         NA         NA       NA    
## ASV3375             NA         NA         NA       NA    
## ASV4317             NA         NA         NA       NA    
## ASV9599             NA         NA         NA       NA    
## ASV0175     -3.581e+31  5.063e+36  0.000e+00    1.000    
## ASV1032             NA         NA         NA       NA    
## ASV1235             NA         NA         NA       NA    
## ASV1262             NA         NA         NA       NA    
## ASV1320             NA         NA         NA       NA    
## ASV13797            NA         NA         NA       NA    
## ASV1491             NA         NA         NA       NA    
## ASV15014            NA         NA         NA       NA    
## ASV1510             NA         NA         NA       NA    
## ASV1551             NA         NA         NA       NA    
## ASV1919             NA         NA         NA       NA    
## ASV2114             NA         NA         NA       NA    
## ASV21486            NA         NA         NA       NA    
## ASV2448             NA         NA         NA       NA    
## ASV2589             NA         NA         NA       NA    
## ASV2608             NA         NA         NA       NA    
## ASV2786             NA         NA         NA       NA    
## ASV2827             NA         NA         NA       NA    
## ASV2872             NA         NA         NA       NA    
## ASV3125             NA         NA         NA       NA    
## ASV3247             NA         NA         NA       NA    
## ASV3451             NA         NA         NA       NA    
## ASV3465             NA         NA         NA       NA    
## ASV3809             NA         NA         NA       NA    
## ASV4006             NA         NA         NA       NA    
## ASV4046             NA         NA         NA       NA    
## ASV4938             NA         NA         NA       NA    
## ASV5435             NA         NA         NA       NA    
## ASV5605             NA         NA         NA       NA    
## ASV5635             NA         NA         NA       NA    
## ASV5743             NA         NA         NA       NA    
## ASV6627             NA         NA         NA       NA    
## ASV6785             NA         NA         NA       NA    
## ASV7368             NA         NA         NA       NA    
## ASV9118             NA         NA         NA       NA    
## ASV9135             NA         NA         NA       NA    
## ASV9435             NA         NA         NA       NA    
## ASV9671             NA         NA         NA       NA    
## ASV0387             NA         NA         NA       NA    
## ASV0454             NA         NA         NA       NA    
## ASV0751             NA         NA         NA       NA    
## ASV1081             NA         NA         NA       NA    
## ASV1332             NA         NA         NA       NA    
## ASV2659             NA         NA         NA       NA    
## ASV2979             NA         NA         NA       NA    
## ASV4184             NA         NA         NA       NA    
## ASV6198             NA         NA         NA       NA    
## ASV7454             NA         NA         NA       NA    
## ASV8198             NA         NA         NA       NA    
## ASV0855             NA         NA         NA       NA    
## ASV10092            NA         NA         NA       NA    
## ASV1532             NA         NA         NA       NA    
## ASV2553             NA         NA         NA       NA    
## ASV2741             NA         NA         NA       NA    
## ASV4095             NA         NA         NA       NA    
## ASV5295             NA         NA         NA       NA    
## ASV5787             NA         NA         NA       NA    
## ASV9455             NA         NA         NA       NA    
## ASV10879            NA         NA         NA       NA    
## ASV3997             NA         NA         NA       NA    
## ASV6760             NA         NA         NA       NA    
## ASV6990             NA         NA         NA       NA    
## ASV9560             NA         NA         NA       NA    
## ASV0220             NA         NA         NA       NA    
## ASV2518             NA         NA         NA       NA    
## ASV3615             NA         NA         NA       NA    
## ASV0075             NA         NA         NA       NA    
## ASV8070             NA         NA         NA       NA    
## ASV1658             NA         NA         NA       NA    
## ASV0773             NA         NA         NA       NA    
## ASV0799             NA         NA         NA       NA    
## ASV1839             NA         NA         NA       NA    
## ASV0265             NA         NA         NA       NA    
## ASV3741             NA         NA         NA       NA    
## ASV0847      5.919e+33  1.280e+37  0.000e+00    1.000    
## ASV1026             NA         NA         NA       NA    
## ASV1222             NA         NA         NA       NA    
## ASV0729             NA         NA         NA       NA    
## ASV0143             NA         NA         NA       NA    
## ASV1328             NA         NA         NA       NA    
## ASV9078             NA         NA         NA       NA    
## ASV0027             NA         NA         NA       NA    
## ASV0546             NA         NA         NA       NA    
## ASV1136             NA         NA         NA       NA    
## ASV3081             NA         NA         NA       NA    
## ASV0531             NA         NA         NA       NA    
## ASV2525             NA         NA         NA       NA    
## ASV1083             NA         NA         NA       NA    
## ASV0424             NA         NA         NA       NA    
## ASV0644             NA         NA         NA       NA    
## ASV6007             NA         NA         NA       NA    
## ASV0564             NA         NA         NA       NA    
## ASV1938             NA         NA         NA       NA    
## ASV6516             NA         NA         NA       NA    
## ASV0503             NA         NA         NA       NA    
## ASV6913             NA         NA         NA       NA    
## ASV0164             NA         NA         NA       NA    
## ASV1576             NA         NA         NA       NA    
## ASV1725             NA         NA         NA       NA    
## ASV4501             NA         NA         NA       NA    
## ASV10678            NA         NA         NA       NA    
## ASV0944             NA         NA         NA       NA    
## ASV2292             NA         NA         NA       NA    
## ASV1090             NA         NA         NA       NA    
## ASV9117             NA         NA         NA       NA    
## ASV0285             NA         NA         NA       NA    
## ASV0463             NA         NA         NA       NA    
## ASV3199             NA         NA         NA       NA    
## ASV0150             NA         NA         NA       NA    
## ASV6583             NA         NA         NA       NA    
## ASV0392             NA         NA         NA       NA    
## ASV14007            NA         NA         NA       NA    
## ASV0177             NA         NA         NA       NA    
## ASV6448             NA         NA         NA       NA    
## ASV5399             NA         NA         NA       NA    
## ASV0277             NA         NA         NA       NA    
## ASV2599             NA         NA         NA       NA    
## ASV13465            NA         NA         NA       NA    
## ASV2412             NA         NA         NA       NA    
## ASV0423             NA         NA         NA       NA    
## ASV5187             NA         NA         NA       NA    
## ASV0701             NA         NA         NA       NA    
## ASV4248             NA         NA         NA       NA    
## ASV0519             NA         NA         NA       NA    
## ASV0764             NA         NA         NA       NA    
## ASV5385             NA         NA         NA       NA    
## ASV3021             NA         NA         NA       NA    
## ASV4119             NA         NA         NA       NA    
## ASV2534             NA         NA         NA       NA    
## ASV1061             NA         NA         NA       NA    
## ASV0670             NA         NA         NA       NA    
## ASV1384             NA         NA         NA       NA    
## ASV1981             NA         NA         NA       NA    
## ASV9632             NA         NA         NA       NA    
## ASV4564             NA         NA         NA       NA    
## ASV5289             NA         NA         NA       NA    
## ASV0516             NA         NA         NA       NA    
## ASV1463             NA         NA         NA       NA    
## ASV0969             NA         NA         NA       NA    
## ASV1113             NA         NA         NA       NA    
## ASV1234             NA         NA         NA       NA    
## ASV3814             NA         NA         NA       NA    
## ASV1000     -6.810e+33  1.279e+37 -1.000e-03    1.000    
## ASV0079             NA         NA         NA       NA    
## ASV0145     -9.941e+32  3.969e+36  0.000e+00    1.000    
## ASV0457             NA         NA         NA       NA    
## ASV1485             NA         NA         NA       NA    
## ASV0535             NA         NA         NA       NA    
## ASV0259             NA         NA         NA       NA    
## ASV0570             NA         NA         NA       NA    
## ASV0906             NA         NA         NA       NA    
## ASV1748             NA         NA         NA       NA    
## ASV5520             NA         NA         NA       NA    
## ASV2288             NA         NA         NA       NA    
## ASV1887             NA         NA         NA       NA    
## ASV0374             NA         NA         NA       NA    
## ASV0823             NA         NA         NA       NA    
## ASV0717             NA         NA         NA       NA    
## ASV0431             NA         NA         NA       NA    
## ASV1030             NA         NA         NA       NA    
## ASV1082             NA         NA         NA       NA    
## ASV2684             NA         NA         NA       NA    
## ASV0051             NA         NA         NA       NA    
## ASV0513             NA         NA         NA       NA    
## ASV0581             NA         NA         NA       NA    
## ASV7282             NA         NA         NA       NA    
## ASV3009             NA         NA         NA       NA    
## ASV2106             NA         NA         NA       NA    
## ASV1012             NA         NA         NA       NA    
## ASV0921             NA         NA         NA       NA    
## ASV0010             NA         NA         NA       NA    
## ASV1178             NA         NA         NA       NA    
## ASV2848             NA         NA         NA       NA    
## ASV0586      4.507e+33  4.181e+36  1.000e-03    0.999    
## ASV4225             NA         NA         NA       NA    
## ASV2156             NA         NA         NA       NA    
## ASV9778             NA         NA         NA       NA    
## ASV0493             NA         NA         NA       NA    
## ASV3770             NA         NA         NA       NA    
## ASV0470             NA         NA         NA       NA    
## ASV0262             NA         NA         NA       NA    
## ASV0998             NA         NA         NA       NA    
## ASV7708             NA         NA         NA       NA    
## ASV0453             NA         NA         NA       NA    
## ASV0044             NA         NA         NA       NA    
## ASV5490             NA         NA         NA       NA    
## ASV2638             NA         NA         NA       NA    
## ASV0829             NA         NA         NA       NA    
## ASV0601             NA         NA         NA       NA    
## ASV0234             NA         NA         NA       NA    
## ASV0133             NA         NA         NA       NA    
## ASV0323             NA         NA         NA       NA    
## ASV0854             NA         NA         NA       NA    
## ASV0110             NA         NA         NA       NA    
## ASV0816             NA         NA         NA       NA    
## ASV1031             NA         NA         NA       NA    
## ASV0144      6.521e+32  5.367e+35  1.000e-03    0.999    
## ASV0020             NA         NA         NA       NA    
## ASV0962             NA         NA         NA       NA    
## ASV0794             NA         NA         NA       NA    
## ASV7117             NA         NA         NA       NA    
## ASV1008             NA         NA         NA       NA    
## ASV0096             NA         NA         NA       NA    
## ASV0128             NA         NA         NA       NA    
## ASV5232             NA         NA         NA       NA    
## ASV0031             NA         NA         NA       NA    
## ASV1744             NA         NA         NA       NA    
## ASV0289     -1.078e+33  4.590e+36  0.000e+00    1.000    
## ASV7413             NA         NA         NA       NA    
## ASV0822             NA         NA         NA       NA    
## ASV8111             NA         NA         NA       NA    
## ASV0687             NA         NA         NA       NA    
## ASV0112             NA         NA         NA       NA    
## ASV0987             NA         NA         NA       NA    
## ASV5332             NA         NA         NA       NA    
## ASV1129             NA         NA         NA       NA    
## ASV1274             NA         NA         NA       NA    
## ASV0119             NA         NA         NA       NA    
## ASV0890             NA         NA         NA       NA    
## ASV0848     -3.263e+33  6.580e+36  0.000e+00    1.000    
## ASV5944             NA         NA         NA       NA    
## ASV19741            NA         NA         NA       NA    
## ASV0504             NA         NA         NA       NA    
## ASV2146             NA         NA         NA       NA    
## ASV0089             NA         NA         NA       NA    
## ASV2301             NA         NA         NA       NA    
## ASV2982             NA         NA         NA       NA    
## ASV0891             NA         NA         NA       NA    
## ASV0093             NA         NA         NA       NA    
## ASV0042             NA         NA         NA       NA    
## ASV0980             NA         NA         NA       NA    
## ASV0069             NA         NA         NA       NA    
## ASV1364             NA         NA         NA       NA    
## ASV0524             NA         NA         NA       NA    
## ASV0435             NA         NA         NA       NA    
## ASV0517             NA         NA         NA       NA    
## ASV3167             NA         NA         NA       NA    
## ASV4280             NA         NA         NA       NA    
## ASV1158             NA         NA         NA       NA    
## ASV2214             NA         NA         NA       NA    
## ASV0544             NA         NA         NA       NA    
## ASV5326             NA         NA         NA       NA    
## ASV3765             NA         NA         NA       NA    
## ASV4646             NA         NA         NA       NA    
## ASV0090             NA         NA         NA       NA    
## ASV3680             NA         NA         NA       NA    
## ASV0111      1.611e+33  6.472e+36  0.000e+00    1.000    
## ASV0768             NA         NA         NA       NA    
## ASV4862             NA         NA         NA       NA    
## ASV1742             NA         NA         NA       NA    
## ASV3701             NA         NA         NA       NA    
## ASV2386             NA         NA         NA       NA    
## ASV0375             NA         NA         NA       NA    
## ASV2796             NA         NA         NA       NA    
## ASV1369             NA         NA         NA       NA    
## ASV10272            NA         NA         NA       NA    
## ASV10354            NA         NA         NA       NA    
## ASV1067             NA         NA         NA       NA    
## ASV1900             NA         NA         NA       NA    
## ASV4079             NA         NA         NA       NA    
## ASV4149             NA         NA         NA       NA    
## ASV5140             NA         NA         NA       NA    
## ASV10782            NA         NA         NA       NA    
## ASV4273             NA         NA         NA       NA    
## ASV8121             NA         NA         NA       NA    
## ASV8438             NA         NA         NA       NA    
## ASV9390             NA         NA         NA       NA    
## ASV1340             NA         NA         NA       NA    
## ASV2650             NA         NA         NA       NA    
## ASV4674             NA         NA         NA       NA    
## ASV10492            NA         NA         NA       NA    
## ASV11430            NA         NA         NA       NA    
## ASV12135            NA         NA         NA       NA    
## ASV14970            NA         NA         NA       NA    
## ASV1954             NA         NA         NA       NA    
## ASV2613             NA         NA         NA       NA    
## ASV2757             NA         NA         NA       NA    
## ASV2909             NA         NA         NA       NA    
## ASV2954             NA         NA         NA       NA    
## ASV2969             NA         NA         NA       NA    
## ASV3410             NA         NA         NA       NA    
## ASV3575             NA         NA         NA       NA    
## ASV4275             NA         NA         NA       NA    
## ASV4652             NA         NA         NA       NA    
## ASV4761             NA         NA         NA       NA    
## ASV6003             NA         NA         NA       NA    
## ASV6110             NA         NA         NA       NA    
## ASV7427             NA         NA         NA       NA    
## ASV8092             NA         NA         NA       NA    
## ASV8169             NA         NA         NA       NA    
## ASV9693             NA         NA         NA       NA    
## ASV10913            NA         NA         NA       NA    
## ASV1979             NA         NA         NA       NA    
## ASV3772             NA         NA         NA       NA    
## ASV0113             NA         NA         NA       NA    
## ASV1800     -7.688e+32  1.585e+36  0.000e+00    1.000    
## ASV2335             NA         NA         NA       NA    
## ASV0692             NA         NA         NA       NA    
## ASV1120             NA         NA         NA       NA    
## ASV1434             NA         NA         NA       NA    
## ASV0076             NA         NA         NA       NA    
## ASV0361             NA         NA         NA       NA    
## ASV2231     -8.934e+32  5.177e+36  0.000e+00    1.000    
## ASV2018             NA         NA         NA       NA    
## ASV1529             NA         NA         NA       NA    
## ASV0841             NA         NA         NA       NA    
## ASV2556             NA         NA         NA       NA    
## ASV2777             NA         NA         NA       NA    
## ASV0355             NA         NA         NA       NA    
## ASV5169             NA         NA         NA       NA    
## ASV3091             NA         NA         NA       NA    
## ASV2435             NA         NA         NA       NA    
## ASV6822             NA         NA         NA       NA    
## ASV12605            NA         NA         NA       NA    
## ASV0286             NA         NA         NA       NA    
## ASV0074             NA         NA         NA       NA    
## ASV2485             NA         NA         NA       NA    
## ASV1233             NA         NA         NA       NA    
## ASV0356             NA         NA         NA       NA    
## ASV2918             NA         NA         NA       NA    
## ASV1427             NA         NA         NA       NA    
## ASV1409             NA         NA         NA       NA    
## ASV0770             NA         NA         NA       NA    
## ASV1403             NA         NA         NA       NA    
## ASV0314             NA         NA         NA       NA    
## ASV0187             NA         NA         NA       NA    
## ASV0313             NA         NA         NA       NA    
## ASV1087             NA         NA         NA       NA    
## ASV1970             NA         NA         NA       NA    
## ASV0754             NA         NA         NA       NA    
## ASV3775             NA         NA         NA       NA    
## ASV0132             NA         NA         NA       NA    
## ASV2329             NA         NA         NA       NA    
## ASV0561             NA         NA         NA       NA    
## ASV0130             NA         NA         NA       NA    
## ASV0226             NA         NA         NA       NA    
## ASV12648            NA         NA         NA       NA    
## ASV0204     -2.008e+33  8.502e+36  0.000e+00    1.000    
## ASV0767             NA         NA         NA       NA    
## ASV0335             NA         NA         NA       NA    
## ASV5901     -6.731e+33  2.253e+37  0.000e+00    1.000    
## ASV0596             NA         NA         NA       NA    
## ASV9271             NA         NA         NA       NA    
## ASV0904             NA         NA         NA       NA    
## ASV15270            NA         NA         NA       NA    
## ASV0990             NA         NA         NA       NA    
## ASV0155             NA         NA         NA       NA    
## ASV0086             NA         NA         NA       NA    
## ASV2581     -1.695e+32  3.090e+36  0.000e+00    1.000    
## ASV1579             NA         NA         NA       NA    
## ASV7730             NA         NA         NA       NA    
## ASV0897             NA         NA         NA       NA    
## ASV1975             NA         NA         NA       NA    
## ASV0759             NA         NA         NA       NA    
## ASV3082             NA         NA         NA       NA    
## ASV3195             NA         NA         NA       NA    
## ASV0427             NA         NA         NA       NA    
## ASV2674             NA         NA         NA       NA    
## ASV1500             NA         NA         NA       NA    
## ASV0102     -3.954e+33  2.600e+37  0.000e+00    1.000    
## ASV1217             NA         NA         NA       NA    
## ASV4998             NA         NA         NA       NA    
## ASV2890             NA         NA         NA       NA    
## ASV0672     -2.250e+33  3.765e+36 -1.000e-03    1.000    
## ASV6960             NA         NA         NA       NA    
## ASV0821             NA         NA         NA       NA    
## ASV1995             NA         NA         NA       NA    
## ASV0211             NA         NA         NA       NA    
## ASV0364             NA         NA         NA       NA    
## ASV3616             NA         NA         NA       NA    
## ASV1996             NA         NA         NA       NA    
## ASV1881             NA         NA         NA       NA    
## ASV1089             NA         NA         NA       NA    
## ASV1450             NA         NA         NA       NA    
## ASV4643             NA         NA         NA       NA    
## ASV3458             NA         NA         NA       NA    
## ASV2543             NA         NA         NA       NA    
## ASV3306             NA         NA         NA       NA    
## ASV0218             NA         NA         NA       NA    
## ASV3727             NA         NA         NA       NA    
## ASV4394             NA         NA         NA       NA    
## ASV2636             NA         NA         NA       NA    
## ASV5116             NA         NA         NA       NA    
## ASV1394             NA         NA         NA       NA    
## ASV0656             NA         NA         NA       NA    
## ASV0475             NA         NA         NA       NA    
## ASV1042             NA         NA         NA       NA    
## ASV1199             NA         NA         NA       NA    
## ASV12962            NA         NA         NA       NA    
## ASV0853             NA         NA         NA       NA    
## ASV5069             NA         NA         NA       NA    
## ASV7825             NA         NA         NA       NA    
## ASV0339             NA         NA         NA       NA    
## ASV2965             NA         NA         NA       NA    
## ASV2347             NA         NA         NA       NA    
## ASV0541             NA         NA         NA       NA    
## ASV0369     -2.789e+33  1.253e+36 -2.000e-03    0.998    
## ASV0171             NA         NA         NA       NA    
## ASV2235             NA         NA         NA       NA    
## ASV5809             NA         NA         NA       NA    
## ASV1267             NA         NA         NA       NA    
## ASV0207             NA         NA         NA       NA    
## ASV3126             NA         NA         NA       NA    
## ASV0183             NA         NA         NA       NA    
## ASV1792             NA         NA         NA       NA    
## ASV2001             NA         NA         NA       NA    
## ASV5732             NA         NA         NA       NA    
## ASV2857             NA         NA         NA       NA    
## ASV1052             NA         NA         NA       NA    
## ASV3226             NA         NA         NA       NA    
## ASV3766             NA         NA         NA       NA    
## ASV0982             NA         NA         NA       NA    
## ASV0489             NA         NA         NA       NA    
## ASV3990             NA         NA         NA       NA    
## ASV0433             NA         NA         NA       NA    
## ASV0684             NA         NA         NA       NA    
## ASV0063     -5.928e+32  2.858e+36  0.000e+00    1.000    
## ASV1399             NA         NA         NA       NA    
## ASV3093             NA         NA         NA       NA    
## ASV1771             NA         NA         NA       NA    
## ASV7910             NA         NA         NA       NA    
## ASV3718             NA         NA         NA       NA    
## ASV0039             NA         NA         NA       NA    
## ASV6469             NA         NA         NA       NA    
## ASV8186             NA         NA         NA       NA    
## ASV1091             NA         NA         NA       NA    
## ASV16930            NA         NA         NA       NA    
## ASV7234             NA         NA         NA       NA    
## ASV1560             NA         NA         NA       NA    
## ASV2968             NA         NA         NA       NA    
## ASV3824             NA         NA         NA       NA    
## ASV0442             NA         NA         NA       NA    
## ASV0677             NA         NA         NA       NA    
## ASV4796             NA         NA         NA       NA    
## ASV2206             NA         NA         NA       NA    
## ASV2884             NA         NA         NA       NA    
## ASV0482             NA         NA         NA       NA    
## ASV1273             NA         NA         NA       NA    
## ASV1910             NA         NA         NA       NA    
## ASV0105             NA         NA         NA       NA    
## ASV0149             NA         NA         NA       NA    
## ASV5007             NA         NA         NA       NA    
## ASV0757             NA         NA         NA       NA    
## ASV11952            NA         NA         NA       NA    
## ASV4102      2.853e+33  7.504e+36  0.000e+00    1.000    
## ASV1034             NA         NA         NA       NA    
## ASV0753             NA         NA         NA       NA    
## ASV2323             NA         NA         NA       NA    
## ASV0881             NA         NA         NA       NA    
## ASV3730             NA         NA         NA       NA    
## ASV2685             NA         NA         NA       NA    
## ASV3826             NA         NA         NA       NA    
## ASV0689             NA         NA         NA       NA    
## ASV4315             NA         NA         NA       NA    
## ASV1239             NA         NA         NA       NA    
## ASV3147             NA         NA         NA       NA    
## ASV3454             NA         NA         NA       NA    
## ASV4411             NA         NA         NA       NA    
## ASV3007             NA         NA         NA       NA    
## ASV6151             NA         NA         NA       NA    
## ASV0834             NA         NA         NA       NA    
## ASV1231             NA         NA         NA       NA    
## ASV0643             NA         NA         NA       NA    
## ASV0924             NA         NA         NA       NA    
## ASV3238             NA         NA         NA       NA    
## ASV1276             NA         NA         NA       NA    
## ASV5503             NA         NA         NA       NA    
## ASV0404             NA         NA         NA       NA    
## ASV3430             NA         NA         NA       NA    
## ASV5401             NA         NA         NA       NA    
## ASV3426     -1.044e+33  1.557e+36 -1.000e-03    0.999    
## ASV0777             NA         NA         NA       NA    
## ASV11093            NA         NA         NA       NA    
## ASV2170             NA         NA         NA       NA    
## ASV3861             NA         NA         NA       NA    
## ASV1723             NA         NA         NA       NA    
## ASV2460             NA         NA         NA       NA    
## ASV1218             NA         NA         NA       NA    
## ASV0436             NA         NA         NA       NA    
## ASV0919             NA         NA         NA       NA    
## ASV0577             NA         NA         NA       NA    
## ASV2517             NA         NA         NA       NA    
## ASV2628             NA         NA         NA       NA    
## ASV1743             NA         NA         NA       NA    
## ASV1678             NA         NA         NA       NA    
## ASV0315             NA         NA         NA       NA    
## ASV0253             NA         NA         NA       NA    
## ASV1363             NA         NA         NA       NA    
## ASV0995             NA         NA         NA       NA    
## ASV4185             NA         NA         NA       NA    
## ASV0782             NA         NA         NA       NA    
## ASV3240             NA         NA         NA       NA    
## ASV1392             NA         NA         NA       NA    
## ASV8488             NA         NA         NA       NA    
## ASV2814             NA         NA         NA       NA    
## ASV0678             NA         NA         NA       NA    
## ASV1295             NA         NA         NA       NA    
## ASV7517             NA         NA         NA       NA    
## ASV2996             NA         NA         NA       NA    
## ASV2882             NA         NA         NA       NA    
## ASV1317             NA         NA         NA       NA    
## ASV9106             NA         NA         NA       NA    
## ASV9688             NA         NA         NA       NA    
## ASV6181             NA         NA         NA       NA    
## ASV2936      1.559e+33  2.228e+36  1.000e-03    0.999    
## ASV0192             NA         NA         NA       NA    
## ASV2509             NA         NA         NA       NA    
## ASV0863             NA         NA         NA       NA    
## ASV2762             NA         NA         NA       NA    
## ASV4904             NA         NA         NA       NA    
## ASV0571             NA         NA         NA       NA    
## ASV13304            NA         NA         NA       NA    
## ASV6863             NA         NA         NA       NA    
## ASV4844             NA         NA         NA       NA    
## ASV10779            NA         NA         NA       NA    
## ASV7921             NA         NA         NA       NA    
## ASV8458             NA         NA         NA       NA    
## ASV2593             NA         NA         NA       NA    
## ASV4410             NA         NA         NA       NA    
## ASV0593             NA         NA         NA       NA    
## ASV2669             NA         NA         NA       NA    
## ASV0868             NA         NA         NA       NA    
## ASV3123             NA         NA         NA       NA    
## ASV3482             NA         NA         NA       NA    
## ASV2552             NA         NA         NA       NA    
## ASV0723             NA         NA         NA       NA    
## ASV0526             NA         NA         NA       NA    
## ASV4623             NA         NA         NA       NA    
## ASV2070             NA         NA         NA       NA    
## ASV1198             NA         NA         NA       NA    
## ASV3034             NA         NA         NA       NA    
## ASV1208             NA         NA         NA       NA    
## ASV4860             NA         NA         NA       NA    
## ASV2493             NA         NA         NA       NA    
## ASV4217             NA         NA         NA       NA    
## ASV1516             NA         NA         NA       NA    
## ASV1186             NA         NA         NA       NA    
## ASV1906             NA         NA         NA       NA    
## ASV8220             NA         NA         NA       NA    
## ASV4227             NA         NA         NA       NA    
## ASV1013             NA         NA         NA       NA    
## ASV7952             NA         NA         NA       NA    
## ASV5923             NA         NA         NA       NA    
## ASV0190             NA         NA         NA       NA    
## ASV0491     -5.012e+32  1.469e+36  0.000e+00    1.000    
## ASV9535             NA         NA         NA       NA    
## ASV9947             NA         NA         NA       NA    
## ASV6518             NA         NA         NA       NA    
## ASV1741             NA         NA         NA       NA    
## ASV1874             NA         NA         NA       NA    
## ASV2150             NA         NA         NA       NA    
## ASV5262             NA         NA         NA       NA    
## ASV1729             NA         NA         NA       NA    
## ASV1522             NA         NA         NA       NA    
## ASV3250             NA         NA         NA       NA    
## ASV4338             NA         NA         NA       NA    
## ASV1386             NA         NA         NA       NA    
## ASV0694             NA         NA         NA       NA    
## ASV2026             NA         NA         NA       NA    
## ASV0191             NA         NA         NA       NA    
## ASV1641             NA         NA         NA       NA    
## ASV1326             NA         NA         NA       NA    
## ASV4786             NA         NA         NA       NA    
## ASV0342             NA         NA         NA       NA    
## ASV3025             NA         NA         NA       NA    
## ASV6533             NA         NA         NA       NA    
## ASV1898             NA         NA         NA       NA    
## ASV1940             NA         NA         NA       NA    
## ASV4968             NA         NA         NA       NA    
## ASV3401             NA         NA         NA       NA    
## ASV3211             NA         NA         NA       NA    
## ASV1489             NA         NA         NA       NA    
## ASV4139             NA         NA         NA       NA    
## ASV6059             NA         NA         NA       NA    
## ASV0918             NA         NA         NA       NA    
## ASV1449      1.445e+33  2.907e+36  0.000e+00    1.000    
## ASV5652             NA         NA         NA       NA    
## ASV4091             NA         NA         NA       NA    
## ASV7638             NA         NA         NA       NA    
## ASV6525             NA         NA         NA       NA    
## ASV8959             NA         NA         NA       NA    
## ASV0699             NA         NA         NA       NA    
## ASV2925             NA         NA         NA       NA    
## ASV0618             NA         NA         NA       NA    
## ASV2083      2.631e+33  7.032e+36  0.000e+00    1.000    
## ASV6192             NA         NA         NA       NA    
## ASV8640             NA         NA         NA       NA    
## ASV1103             NA         NA         NA       NA    
## ASV4240             NA         NA         NA       NA    
## ASV2180             NA         NA         NA       NA    
## ASV9157             NA         NA         NA       NA    
## ASV1307             NA         NA         NA       NA    
## ASV4960             NA         NA         NA       NA    
## ASV3930             NA         NA         NA       NA    
## ASV1200             NA         NA         NA       NA    
## ASV4676             NA         NA         NA       NA    
## ASV6993             NA         NA         NA       NA    
## ASV4813             NA         NA         NA       NA    
## ASV4364             NA         NA         NA       NA    
## ASV0141             NA         NA         NA       NA    
## ASV3509             NA         NA         NA       NA    
## ASV2751             NA         NA         NA       NA    
## ASV4913             NA         NA         NA       NA    
## ASV0138             NA         NA         NA       NA    
## ASV7697             NA         NA         NA       NA    
## ASV1602             NA         NA         NA       NA    
## ASV5976             NA         NA         NA       NA    
## ASV7525             NA         NA         NA       NA    
## ASV4961             NA         NA         NA       NA    
## ASV2546             NA         NA         NA       NA    
## ASV0721             NA         NA         NA       NA    
## ASV0542             NA         NA         NA       NA    
## ASV3865             NA         NA         NA       NA    
## ASV5571             NA         NA         NA       NA    
## ASV6804             NA         NA         NA       NA    
## ASV4424             NA         NA         NA       NA    
## ASV3395             NA         NA         NA       NA    
## ASV2394             NA         NA         NA       NA    
## ASV8629             NA         NA         NA       NA    
## ASV1018             NA         NA         NA       NA    
## ASV6139             NA         NA         NA       NA    
## ASV10411            NA         NA         NA       NA    
## ASV3992             NA         NA         NA       NA    
## ASV7131             NA         NA         NA       NA    
## ASV3729      2.053e+33  5.986e+36  0.000e+00    1.000    
## ASV2197             NA         NA         NA       NA    
## ASV2426             NA         NA         NA       NA    
## ASV3669             NA         NA         NA       NA    
## ASV1820             NA         NA         NA       NA    
## ASV7081             NA         NA         NA       NA    
## ASV7872             NA         NA         NA       NA    
## ASV1670             NA         NA         NA       NA    
## ASV0712             NA         NA         NA       NA    
## ASV0474             NA         NA         NA       NA    
## ASV1196             NA         NA         NA       NA    
## ASV0845             NA         NA         NA       NA    
## ASV12393            NA         NA         NA       NA    
## ASV5867             NA         NA         NA       NA    
## ASV17619            NA         NA         NA       NA    
## ASV4686             NA         NA         NA       NA    
## ASV3520             NA         NA         NA       NA    
## ASV10800            NA         NA         NA       NA    
## ASV2706             NA         NA         NA       NA    
## ASV1227             NA         NA         NA       NA    
## ASV2621             NA         NA         NA       NA    
## ASV0460             NA         NA         NA       NA    
## ASV1069             NA         NA         NA       NA    
## ASV6939             NA         NA         NA       NA    
## ASV2862             NA         NA         NA       NA    
## ASV1021             NA         NA         NA       NA    
## ASV3845             NA         NA         NA       NA    
## ASV0732             NA         NA         NA       NA    
## ASV10731            NA         NA         NA       NA    
## ASV3378             NA         NA         NA       NA    
## ASV7154             NA         NA         NA       NA    
## ASV9876             NA         NA         NA       NA    
## ASV0631             NA         NA         NA       NA    
## ASV13027            NA         NA         NA       NA    
## ASV2497             NA         NA         NA       NA    
## ASV3966             NA         NA         NA       NA    
## ASV2574             NA         NA         NA       NA    
## ASV0545             NA         NA         NA       NA    
## ASV8453             NA         NA         NA       NA    
## ASV0221             NA         NA         NA       NA    
## ASV3305             NA         NA         NA       NA    
## ASV2647             NA         NA         NA       NA    
## ASV5789             NA         NA         NA       NA    
## ASV1731             NA         NA         NA       NA    
## ASV3857             NA         NA         NA       NA    
## ASV0405             NA         NA         NA       NA    
## ASV0094             NA         NA         NA       NA    
## ASV0158             NA         NA         NA       NA    
## ASV5507             NA         NA         NA       NA    
## ASV1023             NA         NA         NA       NA    
## ASV0488             NA         NA         NA       NA    
## ASV1459             NA         NA         NA       NA    
## ASV4349             NA         NA         NA       NA    
## ASV1172             NA         NA         NA       NA    
## ASV10187            NA         NA         NA       NA    
## ASV7227             NA         NA         NA       NA    
## ASV10340            NA         NA         NA       NA    
## ASV10821            NA         NA         NA       NA    
## ASV13810            NA         NA         NA       NA    
## ASV3230             NA         NA         NA       NA    
## ASV5524             NA         NA         NA       NA    
## ASV8742             NA         NA         NA       NA    
## ASV9188             NA         NA         NA       NA    
## ASV4658             NA         NA         NA       NA    
## ASV7889             NA         NA         NA       NA    
## ASV1466             NA         NA         NA       NA    
## ASV1424             NA         NA         NA       NA    
## ASV0098             NA         NA         NA       NA    
## ASV0067             NA         NA         NA       NA    
## ASV9434             NA         NA         NA       NA    
## ASV3270             NA         NA         NA       NA    
## ASV4518             NA         NA         NA       NA    
## ASV7661             NA         NA         NA       NA    
## ASV4223             NA         NA         NA       NA    
## ASV3481             NA         NA         NA       NA    
## ASV7819             NA         NA         NA       NA    
## ASV3095             NA         NA         NA       NA    
## ASV4476             NA         NA         NA       NA    
## ASV1713             NA         NA         NA       NA    
## ASV11165            NA         NA         NA       NA    
## ASV2179             NA         NA         NA       NA    
## ASV3747      3.623e+32  7.290e+36  0.000e+00    1.000    
## ASV1410             NA         NA         NA       NA    
## ASV6069             NA         NA         NA       NA    
## ASV1939             NA         NA         NA       NA    
## ASV7865             NA         NA         NA       NA    
## ASV4488             NA         NA         NA       NA    
## ASV0938             NA         NA         NA       NA    
## ASV7852             NA         NA         NA       NA    
## ASV2503             NA         NA         NA       NA    
## ASV2993             NA         NA         NA       NA    
## ASV3752             NA         NA         NA       NA    
## ASV2557             NA         NA         NA       NA    
## ASV6522             NA         NA         NA       NA    
## ASV0088             NA         NA         NA       NA    
## ASV7935             NA         NA         NA       NA    
## ASV0942             NA         NA         NA       NA    
## ASV7709             NA         NA         NA       NA    
## ASV4588             NA         NA         NA       NA    
## ASV5765             NA         NA         NA       NA    
## ASV3562             NA         NA         NA       NA    
## ASV9076             NA         NA         NA       NA    
## ASV4707             NA         NA         NA       NA    
## ASV2188             NA         NA         NA       NA    
## ASV0613             NA         NA         NA       NA    
## ASV0663             NA         NA         NA       NA    
## ASV3361             NA         NA         NA       NA    
## ASV1478             NA         NA         NA       NA    
## ASV0213             NA         NA         NA       NA    
## ASV7674             NA         NA         NA       NA    
## ASV2137     -3.418e+32  6.469e+35 -1.000e-03    1.000    
## ASV8246             NA         NA         NA       NA    
## ASV0047             NA         NA         NA       NA    
## ASV6117             NA         NA         NA       NA    
## ASV3349             NA         NA         NA       NA    
## ASV10881            NA         NA         NA       NA    
## ASV6979             NA         NA         NA       NA    
## ASV7930             NA         NA         NA       NA    
## ASV7322             NA         NA         NA       NA    
## ASV4927             NA         NA         NA       NA    
## ASV9054             NA         NA         NA       NA    
## ASV2692             NA         NA         NA       NA    
## ASV1666             NA         NA         NA       NA    
## ASV4728             NA         NA         NA       NA    
## ASV3097             NA         NA         NA       NA    
## ASV4962             NA         NA         NA       NA    
## ASV5057             NA         NA         NA       NA    
## ASV2639             NA         NA         NA       NA    
## ASV1808             NA         NA         NA       NA    
## ASV6333             NA         NA         NA       NA    
## ASV4328             NA         NA         NA       NA    
## ASV7707             NA         NA         NA       NA    
## ASV11022            NA         NA         NA       NA    
## ASV1469             NA         NA         NA       NA    
## ASV3919             NA         NA         NA       NA    
## ASV4038             NA         NA         NA       NA    
## ASV4048             NA         NA         NA       NA    
## ASV0634             NA         NA         NA       NA    
## ASV1852             NA         NA         NA       NA    
## ASV2505             NA         NA         NA       NA    
## ASV1762             NA         NA         NA       NA    
## ASV3761             NA         NA         NA       NA    
## ASV0775             NA         NA         NA       NA    
## ASV10911            NA         NA         NA       NA    
## ASV1339             NA         NA         NA       NA    
## ASV5214             NA         NA         NA       NA    
## ASV4945             NA         NA         NA       NA    
## ASV5624             NA         NA         NA       NA    
## ASV3429             NA         NA         NA       NA    
## ASV8416             NA         NA         NA       NA    
## ASV2400             NA         NA         NA       NA    
## ASV3388             NA         NA         NA       NA    
## ASV7089             NA         NA         NA       NA    
## ASV3396             NA         NA         NA       NA    
## ASV0343             NA         NA         NA       NA    
## ASV5505             NA         NA         NA       NA    
## ASV6721             NA         NA         NA       NA    
## ASV0537     -6.942e+32  1.508e+36  0.000e+00    1.000    
## ASV7753             NA         NA         NA       NA    
## ASV5022             NA         NA         NA       NA    
## ASV1073             NA         NA         NA       NA    
## ASV1347             NA         NA         NA       NA    
## ASV15032            NA         NA         NA       NA    
## ASV18213            NA         NA         NA       NA    
## ASV20691            NA         NA         NA       NA    
## ASV4260             NA         NA         NA       NA    
## ASV4923             NA         NA         NA       NA    
## ASV7995             NA         NA         NA       NA    
## ASV8960             NA         NA         NA       NA    
## ASV10682            NA         NA         NA       NA    
## ASV11911            NA         NA         NA       NA    
## ASV14296            NA         NA         NA       NA    
## ASV2314             NA         NA         NA       NA    
## ASV3819             NA         NA         NA       NA    
## ASV4517             NA         NA         NA       NA    
## ASV8941             NA         NA         NA       NA    
## ASV1444             NA         NA         NA       NA    
## ASV5959             NA         NA         NA       NA    
## ASV3623             NA         NA         NA       NA    
## ASV0260             NA         NA         NA       NA    
## ASV4401             NA         NA         NA       NA    
## ASV2891             NA         NA         NA       NA    
## ASV2778             NA         NA         NA       NA    
## ASV8744             NA         NA         NA       NA    
## ASV1079             NA         NA         NA       NA    
## ASV19688            NA         NA         NA       NA    
## ASV4039      8.792e+32  1.892e+36  0.000e+00    1.000    
## ASV4982             NA         NA         NA       NA    
## ASV1071             NA         NA         NA       NA    
## ASV7666             NA         NA         NA       NA    
## ASV0502             NA         NA         NA       NA    
## ASV3624             NA         NA         NA       NA    
## ASV0403      1.420e+32  4.705e+36  0.000e+00    1.000    
## ASV4939             NA         NA         NA       NA    
## ASV6297             NA         NA         NA       NA    
## ASV6343             NA         NA         NA       NA    
## ASV0954             NA         NA         NA       NA    
## ASV10225            NA         NA         NA       NA    
## ASV1584             NA         NA         NA       NA    
## ASV1803             NA         NA         NA       NA    
## ASV2576             NA         NA         NA       NA    
## ASV3252             NA         NA         NA       NA    
## ASV3463             NA         NA         NA       NA    
## ASV3822             NA         NA         NA       NA    
## ASV4926             NA         NA         NA       NA    
## ASV5564             NA         NA         NA       NA    
## ASV5595             NA         NA         NA       NA    
## ASV16463            NA         NA         NA       NA    
## ASV6277             NA         NA         NA       NA    
## ASV1344             NA         NA         NA       NA    
## ASV1869             NA         NA         NA       NA    
## ASV8155             NA         NA         NA       NA    
## ASV2502             NA         NA         NA       NA    
## ASV6742             NA         NA         NA       NA    
## ASV3124             NA         NA         NA       NA    
## ASV17042            NA         NA         NA       NA    
## ASV0248             NA         NA         NA       NA    
## ASV4557             NA         NA         NA       NA    
## ASV3507             NA         NA         NA       NA    
## ASV1870             NA         NA         NA       NA    
## ASV2447             NA         NA         NA       NA    
## ASV0347             NA         NA         NA       NA    
## ASV1855             NA         NA         NA       NA    
## ASV0568             NA         NA         NA       NA    
## ASV1620             NA         NA         NA       NA    
## ASV0101             NA         NA         NA       NA    
## ASV7751             NA         NA         NA       NA    
## ASV9033             NA         NA         NA       NA    
## ASV3438             NA         NA         NA       NA    
## ASV0637             NA         NA         NA       NA    
## ASV1181             NA         NA         NA       NA    
## ASV13480            NA         NA         NA       NA    
## ASV14220            NA         NA         NA       NA    
## ASV1448             NA         NA         NA       NA    
## ASV1457             NA         NA         NA       NA    
## ASV1645             NA         NA         NA       NA    
## ASV2300             NA         NA         NA       NA    
## ASV2533             NA         NA         NA       NA    
## ASV5059             NA         NA         NA       NA    
## ASV8871             NA         NA         NA       NA    
## ASV1289             NA         NA         NA       NA    
## ASV3983             NA         NA         NA       NA    
## ASV10323            NA         NA         NA       NA    
## ASV13279            NA         NA         NA       NA    
## ASV7149             NA         NA         NA       NA    
## ASV1691             NA         NA         NA       NA    
## ASV1649             NA         NA         NA       NA    
## ASV10120     1.943e+33  1.290e+36  2.000e-03    0.999    
## ASV8285             NA         NA         NA       NA    
## ASV0037             NA         NA         NA       NA    
## ASV1770             NA         NA         NA       NA    
## ASV2252             NA         NA         NA       NA    
## ASV7580             NA         NA         NA       NA    
## ASV5643             NA         NA         NA       NA    
## ASV2722             NA         NA         NA       NA    
## ASV2662             NA         NA         NA       NA    
## ASV0479             NA         NA         NA       NA    
## ASV2009             NA         NA         NA       NA    
## ASV3731             NA         NA         NA       NA    
## ASV5497             NA         NA         NA       NA    
## ASV6647             NA         NA         NA       NA    
## ASV8974             NA         NA         NA       NA    
## ASV15527            NA         NA         NA       NA    
## ASV6705      3.039e+33  9.068e+36  0.000e+00    1.000    
## ASV0354             NA         NA         NA       NA    
## ASV2707             NA         NA         NA       NA    
## ASV11167            NA         NA         NA       NA    
## ASV6393             NA         NA         NA       NA    
## ASV3808             NA         NA         NA       NA    
## ASV9337             NA         NA         NA       NA    
## ASV5043      3.768e+32  1.984e+36  0.000e+00    1.000    
## ASV4189             NA         NA         NA       NA    
## ASV1304             NA         NA         NA       NA    
## ASV2105             NA         NA         NA       NA    
## ASV2421             NA         NA         NA       NA    
## ASV3170             NA         NA         NA       NA    
## ASV5036             NA         NA         NA       NA    
## ASV2286             NA         NA         NA       NA    
## ASV3363             NA         NA         NA       NA    
## ASV5759             NA         NA         NA       NA    
## ASV5440             NA         NA         NA       NA    
## ASV2050             NA         NA         NA       NA    
## ASV4478             NA         NA         NA       NA    
## ASV5725             NA         NA         NA       NA    
## ASV1600             NA         NA         NA       NA    
## ASV1654             NA         NA         NA       NA    
## ASV3781             NA         NA         NA       NA    
## ASV7144             NA         NA         NA       NA    
## ASV12710            NA         NA         NA       NA    
## ASV3317             NA         NA         NA       NA    
## ASV3249             NA         NA         NA       NA    
## ASV0669             NA         NA         NA       NA    
## ASV0893             NA         NA         NA       NA    
## ASV11060            NA         NA         NA       NA    
## ASV3207             NA         NA         NA       NA    
## ASV3498             NA         NA         NA       NA    
## ASV4358             NA         NA         NA       NA    
## ASV4806             NA         NA         NA       NA    
## ASV4941             NA         NA         NA       NA    
## ASV6998             NA         NA         NA       NA    
## ASV7327             NA         NA         NA       NA    
## ASV5112             NA         NA         NA       NA    
## ASV5345             NA         NA         NA       NA    
## ASV8911             NA         NA         NA       NA    
## ASV5061             NA         NA         NA       NA    
## ASV1968             NA         NA         NA       NA    
## ASV4669             NA         NA         NA       NA    
## ASV6209             NA         NA         NA       NA    
## ASV6938             NA         NA         NA       NA    
## ASV6987             NA         NA         NA       NA    
## ASV7842             NA         NA         NA       NA    
## ASV17950            NA         NA         NA       NA    
## ASV3380             NA         NA         NA       NA    
## ASV13740            NA         NA         NA       NA    
## ASV4313             NA         NA         NA       NA    
## ASV3891             NA         NA         NA       NA    
## ASV3322      1.794e+33  2.673e+36  1.000e-03    0.999    
## ASV1668             NA         NA         NA       NA    
## ASV1739             NA         NA         NA       NA    
## ASV3194             NA         NA         NA       NA    
## ASV0071             NA         NA         NA       NA    
## ASV0695             NA         NA         NA       NA    
## ASV3835             NA         NA         NA       NA    
## ASV1876             NA         NA         NA       NA    
## ASV4892             NA         NA         NA       NA    
## ASV1212             NA         NA         NA       NA    
## ASV2640             NA         NA         NA       NA    
## ASV7236             NA         NA         NA       NA    
## ASV2353             NA         NA         NA       NA    
## ASV0276             NA         NA         NA       NA    
## ASV2262             NA         NA         NA       NA    
## ASV11201            NA         NA         NA       NA    
## ASV0665             NA         NA         NA       NA    
## ASV5238             NA         NA         NA       NA    
## ASV6885             NA         NA         NA       NA    
## ASV1844             NA         NA         NA       NA    
## ASV0379             NA         NA         NA       NA    
## ASV1040             NA         NA         NA       NA    
## ASV7913             NA         NA         NA       NA    
## ASV1197             NA         NA         NA       NA    
## ASV5918             NA         NA         NA       NA    
## ASV8045             NA         NA         NA       NA    
## ASV16458            NA         NA         NA       NA    
## ASV10827            NA         NA         NA       NA    
## ASV3658             NA         NA         NA       NA    
## ASV0073             NA         NA         NA       NA    
## ASV1951             NA         NA         NA       NA    
## ASV7630             NA         NA         NA       NA    
## ASV9449             NA         NA         NA       NA    
## ASV3944     -1.164e+33  5.862e+36  0.000e+00    1.000    
## ASV1520             NA         NA         NA       NA    
## ASV0307             NA         NA         NA       NA    
## ASV12731            NA         NA         NA       NA    
## ASV0282             NA         NA         NA       NA    
## ASV2646             NA         NA         NA       NA    
## ASV3536             NA         NA         NA       NA    
## ASV10089            NA         NA         NA       NA    
## ASV1185             NA         NA         NA       NA    
## ASV1452             NA         NA         NA       NA    
## ASV1700             NA         NA         NA       NA    
## ASV6948             NA         NA         NA       NA    
## ASV0389             NA         NA         NA       NA    
## ASV11884            NA         NA         NA       NA    
## ASV23165            NA         NA         NA       NA    
## ASV2841             NA         NA         NA       NA    
## ASV2949             NA         NA         NA       NA    
## ASV4037             NA         NA         NA       NA    
## ASV4477             NA         NA         NA       NA    
## ASV4496             NA         NA         NA       NA    
## ASV5784             NA         NA         NA       NA    
## ASV6035             NA         NA         NA       NA    
## ASV6232             NA         NA         NA       NA    
## ASV1818             NA         NA         NA       NA    
## ASV2595             NA         NA         NA       NA    
## ASV2788             NA         NA         NA       NA    
## ASV5018             NA         NA         NA       NA    
## ASV0127             NA         NA         NA       NA    
## ASV1527             NA         NA         NA       NA    
## ASV1055             NA         NA         NA       NA    
## ASV4791             NA         NA         NA       NA    
## ASV0859             NA         NA         NA       NA    
## ASV12971            NA         NA         NA       NA    
## ASV16856            NA         NA         NA       NA    
## ASV7321             NA         NA         NA       NA    
## ASV8780             NA         NA         NA       NA    
## ASV1569             NA         NA         NA       NA    
## ASV3696             NA         NA         NA       NA    
## ASV0624             NA         NA         NA       NA    
## ASV0495             NA         NA         NA       NA    
## ASV16971            NA         NA         NA       NA    
## ASV6535             NA         NA         NA       NA    
## ASV1897             NA         NA         NA       NA    
## ASV2631             NA         NA         NA       NA    
## ASV6204             NA         NA         NA       NA    
## ASV3312             NA         NA         NA       NA    
## ASV3360             NA         NA         NA       NA    
## ASV3907             NA         NA         NA       NA    
## ASV6090             NA         NA         NA       NA    
## ASV8652             NA         NA         NA       NA    
## ASV11129            NA         NA         NA       NA    
## ASV11073            NA         NA         NA       NA    
## ASV1840             NA         NA         NA       NA    
## ASV2298             NA         NA         NA       NA    
## ASV2420             NA         NA         NA       NA    
## ASV6474             NA         NA         NA       NA    
## ASV8475             NA         NA         NA       NA    
## ASV8679             NA         NA         NA       NA    
## ASV6527             NA         NA         NA       NA    
## ASV2504             NA         NA         NA       NA    
## ASV1093             NA         NA         NA       NA    
## ASV0994             NA         NA         NA       NA    
## ASV0092             NA         NA         NA       NA    
## ASV2619             NA         NA         NA       NA    
## ASV0121             NA         NA         NA       NA    
## ASV0932             NA         NA         NA       NA    
## ASV5229             NA         NA         NA       NA    
## ASV6737             NA         NA         NA       NA    
## ASV11213            NA         NA         NA       NA    
## ASV1151             NA         NA         NA       NA    
## ASV3813             NA         NA         NA       NA    
## ASV5566             NA         NA         NA       NA    
## ASV7529             NA         NA         NA       NA    
## ASV2193             NA         NA         NA       NA    
## ASV2349             NA         NA         NA       NA    
## ASV2387             NA         NA         NA       NA    
## ASV2699             NA         NA         NA       NA    
## ASV3353             NA         NA         NA       NA    
## ASV3621             NA         NA         NA       NA    
## ASV3848             NA         NA         NA       NA    
## ASV4440             NA         NA         NA       NA    
## ASV4751             NA         NA         NA       NA    
## ASV5115             NA         NA         NA       NA    
## ASV5850             NA         NA         NA       NA    
## ASV6293             NA         NA         NA       NA    
## ASV6513             NA         NA         NA       NA    
## ASV7628             NA         NA         NA       NA    
## ASV7658             NA         NA         NA       NA    
## ASV0776             NA         NA         NA       NA    
## ASV10227            NA         NA         NA       NA    
## ASV11965            NA         NA         NA       NA    
## ASV1270             NA         NA         NA       NA    
## ASV13123            NA         NA         NA       NA    
## ASV5828             NA         NA         NA       NA    
## ASV5920             NA         NA         NA       NA    
## ASV6071             NA         NA         NA       NA    
## ASV6723             NA         NA         NA       NA    
## ASV6727             NA         NA         NA       NA    
## ASV7759             NA         NA         NA       NA    
## ASV0733             NA         NA         NA       NA    
## ASV1655             NA         NA         NA       NA    
## ASV0755             NA         NA         NA       NA    
## ASV0796             NA         NA         NA       NA    
## ASV0878             NA         NA         NA       NA    
## ASV4988             NA         NA         NA       NA    
## ASV0083             NA         NA         NA       NA    
## ASV0273             NA         NA         NA       NA    
## ASV3076             NA         NA         NA       NA    
## ASV1513             NA         NA         NA       NA    
## ASV5159             NA         NA         NA       NA    
## ASV3422             NA         NA         NA       NA    
## ASV12230            NA         NA         NA       NA    
## ASV1694             NA         NA         NA       NA    
## ASV1249             NA         NA         NA       NA    
## ASV1697             NA         NA         NA       NA    
## ASV4408             NA         NA         NA       NA    
## ASV0095      4.185e+33  2.057e+37  0.000e+00    1.000    
## ASV0410             NA         NA         NA       NA    
## ASV4642             NA         NA         NA       NA    
## ASV4560             NA         NA         NA       NA    
## ASV7586      1.563e+33  7.193e+36  0.000e+00    1.000    
## ASV4144             NA         NA         NA       NA    
## ASV0327             NA         NA         NA       NA    
## ASV0946             NA         NA         NA       NA    
## ASV3254             NA         NA         NA       NA    
## ASV0349             NA         NA         NA       NA    
## ASV0472             NA         NA         NA       NA    
## ASV1330             NA         NA         NA       NA    
## ASV2605             NA         NA         NA       NA    
## ASV2846             NA         NA         NA       NA    
## ASV3982             NA         NA         NA       NA    
## ASV4116             NA         NA         NA       NA    
## ASV6048             NA         NA         NA       NA    
## ASV1146             NA         NA         NA       NA    
## ASV13362            NA         NA         NA       NA    
## ASV1422             NA         NA         NA       NA    
## ASV3640             NA         NA         NA       NA    
## ASV5404             NA         NA         NA       NA    
## ASV6118             NA         NA         NA       NA    
## ASV1115             NA         NA         NA       NA    
## ASV0888             NA         NA         NA       NA    
## ASV4620             NA         NA         NA       NA    
## ASV3099             NA         NA         NA       NA    
## ASV7099             NA         NA         NA       NA    
## ASV5892             NA         NA         NA       NA    
## ASV6978             NA         NA         NA       NA    
## ASV6555             NA         NA         NA       NA    
## ASV0539             NA         NA         NA       NA    
## ASV4665             NA         NA         NA       NA    
## ASV2210             NA         NA         NA       NA    
## ASV1329             NA         NA         NA       NA    
## ASV7123             NA         NA         NA       NA    
## ASV1260             NA         NA         NA       NA    
## ASV1011             NA         NA         NA       NA    
## ASV4233      2.550e+33  1.286e+37  0.000e+00    1.000    
## ASV1475             NA         NA         NA       NA    
## ASV6099             NA         NA         NA       NA    
## ASV1428             NA         NA         NA       NA    
## ASV5101             NA         NA         NA       NA    
## ASV11827            NA         NA         NA       NA    
## ASV13899            NA         NA         NA       NA    
## ASV21259            NA         NA         NA       NA    
## ASV6635             NA         NA         NA       NA    
## ASV9922             NA         NA         NA       NA    
## ASV2869             NA         NA         NA       NA    
## ASV1740             NA         NA         NA       NA    
## ASV4406             NA         NA         NA       NA    
## ASV5586             NA         NA         NA       NA    
## ASV3255             NA         NA         NA       NA    
## ASV12281            NA         NA         NA       NA    
## ASV5388             NA         NA         NA       NA    
## ASV17660            NA         NA         NA       NA    
## ASV0159             NA         NA         NA       NA    
## ASV2734             NA         NA         NA       NA    
## ASV2049             NA         NA         NA       NA    
## ASV2465             NA         NA         NA       NA    
## ASV2147             NA         NA         NA       NA    
## ASV3113             NA         NA         NA       NA    
## ASV0622             NA         NA         NA       NA    
## ASV0437             NA         NA         NA       NA    
## ASV6385             NA         NA         NA       NA    
## ASV3699      3.631e+33  1.523e+37  0.000e+00    1.000    
## ASV2208      5.399e+33  1.989e+37  0.000e+00    1.000    
## ASV1053             NA         NA         NA       NA    
## ASV8468             NA         NA         NA       NA    
## ASV0951             NA         NA         NA       NA    
## ASV0278             NA         NA         NA       NA    
## ASV0914             NA         NA         NA       NA    
## ASV0737             NA         NA         NA       NA    
## ASV2038             NA         NA         NA       NA    
## ASV2171             NA         NA         NA       NA    
## ASV2607             NA         NA         NA       NA    
## ASV3143             NA         NA         NA       NA    
## ASV3187             NA         NA         NA       NA    
## ASV3810             NA         NA         NA       NA    
## ASV5060             NA         NA         NA       NA    
## ASV5325             NA         NA         NA       NA    
## ASV6905             NA         NA         NA       NA    
## ASV7597             NA         NA         NA       NA    
## ASV9652             NA         NA         NA       NA    
## ASV2634             NA         NA         NA       NA    
## ASV3065             NA         NA         NA       NA    
## ASV3331             NA         NA         NA       NA    
## ASV7434             NA         NA         NA       NA    
## ASV7720             NA         NA         NA       NA    
## ASV8414             NA         NA         NA       NA    
## ASV12139            NA         NA         NA       NA    
## ASV1824             NA         NA         NA       NA    
## ASV2094             NA         NA         NA       NA    
## ASV2770             NA         NA         NA       NA    
## ASV3505             NA         NA         NA       NA    
## ASV1935             NA         NA         NA       NA    
## ASV5764             NA         NA         NA       NA    
## ASV6806             NA         NA         NA       NA    
## ASV6942             NA         NA         NA       NA    
## ASV1166             NA         NA         NA       NA    
## ASV1664             NA         NA         NA       NA    
## ASV2568             NA         NA         NA       NA    
## ASV3525             NA         NA         NA       NA    
## ASV4965             NA         NA         NA       NA    
## ASV6607             NA         NA         NA       NA    
## ASV7187             NA         NA         NA       NA    
## ASV0388             NA         NA         NA       NA    
## ASV1420             NA         NA         NA       NA    
## ASV14293            NA         NA         NA       NA    
## ASV17785            NA         NA         NA       NA    
## ASV7678             NA         NA         NA       NA    
## ASV2253             NA         NA         NA       NA    
## ASV4150             NA         NA         NA       NA    
## ASV3836             NA         NA         NA       NA    
## ASV16231            NA         NA         NA       NA    
## ASV2730             NA         NA         NA       NA    
## ASV2072             NA         NA         NA       NA    
## ASV2160             NA         NA         NA       NA    
## ASV5013             NA         NA         NA       NA    
## ASV2586             NA         NA         NA       NA    
## ASV1442             NA         NA         NA       NA    
## ASV3101             NA         NA         NA       NA    
## ASV3323             NA         NA         NA       NA    
## ASV1812             NA         NA         NA       NA    
## ASV6120             NA         NA         NA       NA    
## ASV2565             NA         NA         NA       NA    
## ASV6687             NA         NA         NA       NA    
## ASV5357             NA         NA         NA       NA    
## ASV9383             NA         NA         NA       NA    
## ASV11753            NA         NA         NA       NA    
## ASV11512            NA         NA         NA       NA    
## ASV2791             NA         NA         NA       NA    
## ASV0664             NA         NA         NA       NA    
## ASV3436             NA         NA         NA       NA    
## ASV5755             NA         NA         NA       NA    
## ASV10970            NA         NA         NA       NA    
## ASV11798            NA         NA         NA       NA    
## ASV18193            NA         NA         NA       NA    
## ASV2548             NA         NA         NA       NA    
## ASV3901             NA         NA         NA       NA    
## ASV5197             NA         NA         NA       NA    
## ASV5859             NA         NA         NA       NA    
## ASV6240             NA         NA         NA       NA    
## ASV7281             NA         NA         NA       NA    
## ASV7635             NA         NA         NA       NA    
## ASV8822             NA         NA         NA       NA    
## ASV4810             NA         NA         NA       NA    
## ASV5308             NA         NA         NA       NA    
## ASV2749             NA         NA         NA       NA    
## ASV0298             NA         NA         NA       NA    
## ASV2597             NA         NA         NA       NA    
## ASV5758             NA         NA         NA       NA    
## ASV9987             NA         NA         NA       NA    
## ASV0971             NA         NA         NA       NA    
## ASV0627             NA         NA         NA       NA    
## ASV1758             NA         NA         NA       NA    
## ASV4559             NA         NA         NA       NA    
## ASV11400            NA         NA         NA       NA    
## ASV11559            NA         NA         NA       NA    
## ASV3943             NA         NA         NA       NA    
## ASV10389            NA         NA         NA       NA    
## ASV5168             NA         NA         NA       NA    
## ASV5724             NA         NA         NA       NA    
## ASV6337             NA         NA         NA       NA    
## ASV11063            NA         NA         NA       NA    
## ASV4279             NA         NA         NA       NA    
## ASV7660             NA         NA         NA       NA    
## ASV8218             NA         NA         NA       NA    
## ASV3574             NA         NA         NA       NA    
## ASV12050            NA         NA         NA       NA    
## ASV3897             NA         NA         NA       NA    
## ASV3856             NA         NA         NA       NA    
## ASV3024             NA         NA         NA       NA    
## ASV8715             NA         NA         NA       NA    
## ASV6917             NA         NA         NA       NA    
## ASV1132             NA         NA         NA       NA    
## ASV3583             NA         NA         NA       NA    
## ASV0328             NA         NA         NA       NA    
## ASV0915             NA         NA         NA       NA    
## ASV2677             NA         NA         NA       NA    
## ASV0599             NA         NA         NA       NA    
## ASV0283             NA         NA         NA       NA    
## ASV1028             NA         NA         NA       NA    
## ASV0523             NA         NA         NA       NA    
## ASV8201             NA         NA         NA       NA    
## ASV2795             NA         NA         NA       NA    
## ASV3563             NA         NA         NA       NA    
## ASV1553             NA         NA         NA       NA    
## ASV7155             NA         NA         NA       NA    
## ASV0365             NA         NA         NA       NA    
## ASV8583             NA         NA         NA       NA    
## ASV5400             NA         NA         NA       NA    
## ASV5908             NA         NA         NA       NA    
## ASV2075             NA         NA         NA       NA    
## ASV2520             NA         NA         NA       NA    
## ASV9596             NA         NA         NA       NA    
## ASV1131             NA         NA         NA       NA    
## ASV0579             NA         NA         NA       NA    
## ASV0288             NA         NA         NA       NA    
## ASV4053             NA         NA         NA       NA    
## ASV1736             NA         NA         NA       NA    
## ASV1254             NA         NA         NA       NA    
## ASV9038             NA         NA         NA       NA    
## ASV4746             NA         NA         NA       NA    
## ASV5803             NA         NA         NA       NA    
## ASV0525             NA         NA         NA       NA    
## ASV1974             NA         NA         NA       NA    
## ASV1827             NA         NA         NA       NA    
## ASV30780            NA         NA         NA       NA    
## ASV9342             NA         NA         NA       NA    
## ASV21626            NA         NA         NA       NA    
## ASV1232             NA         NA         NA       NA    
## ASV5578             NA         NA         NA       NA    
## ASV5868             NA         NA         NA       NA    
## ASV13625            NA         NA         NA       NA    
## ASV3614             NA         NA         NA       NA    
## ASV2128             NA         NA         NA       NA    
## ASV5086             NA         NA         NA       NA    
## ASV6614             NA         NA         NA       NA    
## ASV9451             NA         NA         NA       NA    
## ASV9533             NA         NA         NA       NA    
## ASV10697            NA         NA         NA       NA    
## ASV1473             NA         NA         NA       NA    
## ASV1414             NA         NA         NA       NA    
## ASV1567             NA         NA         NA       NA    
## ASV6395             NA         NA         NA       NA    
## ASV2366             NA         NA         NA       NA    
## ASV2537             NA         NA         NA       NA    
## ASV5378             NA         NA         NA       NA    
## ASV5929             NA         NA         NA       NA    
## ASV6360             NA         NA         NA       NA    
## ASV7916             NA         NA         NA       NA    
## ASV13322            NA         NA         NA       NA    
## ASV6207             NA         NA         NA       NA    
## ASV8823             NA         NA         NA       NA    
## ASV1379             NA         NA         NA       NA    
## ASV3259             NA         NA         NA       NA    
## ASV18748            NA         NA         NA       NA    
## ASV3570             NA         NA         NA       NA    
## ASV0790             NA         NA         NA       NA    
## ASV5149             NA         NA         NA       NA    
## ASV1730             NA         NA         NA       NA    
## ASV3488             NA         NA         NA       NA    
## ASV5486             NA         NA         NA       NA    
## ASV1319             NA         NA         NA       NA    
## ASV15328            NA         NA         NA       NA    
## ASV5994             NA         NA         NA       NA    
## ASV4992             NA         NA         NA       NA    
## ASV1788             NA         NA         NA       NA    
## ASV3264             NA         NA         NA       NA    
## ASV4895             NA         NA         NA       NA    
## ASV9218             NA         NA         NA       NA    
## ASV0736             NA         NA         NA       NA    
## ASV0916             NA         NA         NA       NA    
## ASV15761            NA         NA         NA       NA    
## ASV4191             NA         NA         NA       NA    
## ASV3268             NA         NA         NA       NA    
## ASV15321            NA         NA         NA       NA    
## ASV0708             NA         NA         NA       NA    
## ASV4100             NA         NA         NA       NA    
## ASV1627             NA         NA         NA       NA    
## ASV7045             NA         NA         NA       NA    
## ASV3271             NA         NA         NA       NA    
## ASV6200             NA         NA         NA       NA    
## ASV2727             NA         NA         NA       NA    
## ASV3523             NA         NA         NA       NA    
## ASV2259             NA         NA         NA       NA    
## ASV0181             NA         NA         NA       NA    
## ASV1680             NA         NA         NA       NA    
## ASV0176             NA         NA         NA       NA    
## ASV10458            NA         NA         NA       NA    
## ASV10658            NA         NA         NA       NA    
## ASV16807            NA         NA         NA       NA    
## ASV2113             NA         NA         NA       NA    
## ASV2403             NA         NA         NA       NA    
## ASV2484             NA         NA         NA       NA    
## ASV8876             NA         NA         NA       NA    
## ASV0386             NA         NA         NA       NA    
## ASV0351             NA         NA         NA       NA    
## ASV4942             NA         NA         NA       NA    
## ASV5128             NA         NA         NA       NA    
## ASV3496             NA         NA         NA       NA    
## ASV3329             NA         NA         NA       NA    
## ASV7878             NA         NA         NA       NA    
## ASV8251             NA         NA         NA       NA    
## ASV15958            NA         NA         NA       NA    
## ASV7972             NA         NA         NA       NA    
## ASV2088             NA         NA         NA       NA    
## ASV3054             NA         NA         NA       NA    
## ASV4494             NA         NA         NA       NA    
## ASV0087             NA         NA         NA       NA    
## ASV1614             NA         NA         NA       NA    
## ASV3037             NA         NA         NA       NA    
## ASV6615             NA         NA         NA       NA    
## ASV1027             NA         NA         NA       NA    
## ASV2754             NA         NA         NA       NA    
## ASV0536             NA         NA         NA       NA    
## ASV2318             NA         NA         NA       NA    
## ASV5954             NA         NA         NA       NA    
## ASV9028             NA         NA         NA       NA    
## ASV6600             NA         NA         NA       NA    
## ASV1923             NA         NA         NA       NA    
## ASV4034             NA         NA         NA       NA    
## ASV9933             NA         NA         NA       NA    
## ASV1575             NA         NA         NA       NA    
## ASV7812             NA         NA         NA       NA    
## ASV0515             NA         NA         NA       NA    
## ASV1149             NA         NA         NA       NA    
## ASV3791             NA         NA         NA       NA    
## ASV4065             NA         NA         NA       NA    
## ASV10631            NA         NA         NA       NA    
## ASV2359             NA         NA         NA       NA    
## ASV3206             NA         NA         NA       NA    
## ASV4415             NA         NA         NA       NA    
## ASV4467             NA         NA         NA       NA    
## ASV5598             NA         NA         NA       NA    
## ASV5910             NA         NA         NA       NA    
## ASV9494             NA         NA         NA       NA    
## ASV6548             NA         NA         NA       NA    
## ASV8669             NA         NA         NA       NA    
## ASV0674             NA         NA         NA       NA    
## ASV0061             NA         NA         NA       NA    
## ASV0310             NA         NA         NA       NA    
## ASV0582             NA         NA         NA       NA    
## ASV0739             NA         NA         NA       NA    
## ASV1557             NA         NA         NA       NA    
## ASV0146             NA         NA         NA       NA    
## ASV3832             NA         NA         NA       NA    
## ASV0734             NA         NA         NA       NA    
## ASV3036             NA         NA         NA       NA    
## ASV0240             NA         NA         NA       NA    
## ASV2513             NA         NA         NA       NA    
## ASV1118             NA         NA         NA       NA    
## ASV7286             NA         NA         NA       NA    
## ASV1077             NA         NA         NA       NA    
## ASV1255             NA         NA         NA       NA    
## ASV1794             NA         NA         NA       NA    
## ASV2439             NA         NA         NA       NA    
## ASV2467             NA         NA         NA       NA    
## ASV3346             NA         NA         NA       NA    
## ASV3973             NA         NA         NA       NA    
## ASV4521             NA         NA         NA       NA    
## ASV1909             NA         NA         NA       NA    
## ASV3855             NA         NA         NA       NA    
## ASV0810             NA         NA         NA       NA    
## ASV1765             NA         NA         NA       NA    
## ASV0763             NA         NA         NA       NA    
## ASV0302             NA         NA         NA       NA    
## ASV2643             NA         NA         NA       NA    
## ASV0440             NA         NA         NA       NA    
## ASV4899             NA         NA         NA       NA    
## ASV0287             NA         NA         NA       NA    
## ASV3220             NA         NA         NA       NA    
## ASV1007             NA         NA         NA       NA    
## ASV2929             NA         NA         NA       NA    
## ASV1496             NA         NA         NA       NA    
## ASV4975             NA         NA         NA       NA    
## ASV4392             NA         NA         NA       NA    
## ASV4653             NA         NA         NA       NA    
## ASV0230             NA         NA         NA       NA    
## ASV0840             NA         NA         NA       NA    
## ASV4132             NA         NA         NA       NA    
## ASV3344             NA         NA         NA       NA    
## ASV12096            NA         NA         NA       NA    
## ASV1550             NA         NA         NA       NA    
## ASV3542             NA         NA         NA       NA    
## ASV8795             NA         NA         NA       NA    
## ASV2532             NA         NA         NA       NA    
## ASV3087             NA         NA         NA       NA    
## ASV9476             NA         NA         NA       NA    
## ASV13721            NA         NA         NA       NA    
## ASV3842             NA         NA         NA       NA    
## ASV1663             NA         NA         NA       NA    
## ASV0432             NA         NA         NA       NA    
## ASV4356             NA         NA         NA       NA    
## ASV4524             NA         NA         NA       NA    
## ASV0169             NA         NA         NA       NA    
## ASV0368             NA         NA         NA       NA    
## ASV2603             NA         NA         NA       NA    
## ASV3777             NA         NA         NA       NA    
## ASV3978             NA         NA         NA       NA    
## ASV0413             NA         NA         NA       NA    
## ASV0997             NA         NA         NA       NA    
## ASV1195             NA         NA         NA       NA    
## ASV2522             NA         NA         NA       NA    
## ASV4733             NA         NA         NA       NA    
## ASV1063             NA         NA         NA       NA    
## ASV0612             NA         NA         NA       NA    
## ASV1903             NA         NA         NA       NA    
## ASV3576             NA         NA         NA       NA    
## ASV4285             NA         NA         NA       NA    
## ASV3406             NA         NA         NA       NA    
## ASV2379             NA         NA         NA       NA    
## ASV0528             NA         NA         NA       NA    
## ASV6190             NA         NA         NA       NA    
## ASV1537             NA         NA         NA       NA    
## ASV16780            NA         NA         NA       NA    
## ASV0477             NA         NA         NA       NA    
## ASV1499             NA         NA         NA       NA    
## ASV14736            NA         NA         NA       NA    
## ASV0179             NA         NA         NA       NA    
## ASV3153             NA         NA         NA       NA    
## ASV0266             NA         NA         NA       NA    
## ASV0761             NA         NA         NA       NA    
## ASV0269             NA         NA         NA       NA    
## ASV7259             NA         NA         NA       NA    
## ASV2067             NA         NA         NA       NA    
## ASV2985             NA         NA         NA       NA    
## ASV0975             NA         NA         NA       NA    
## ASV2240             NA         NA         NA       NA    
## ASV2297             NA         NA         NA       NA    
## ASV2657             NA         NA         NA       NA    
## ASV3784             NA         NA         NA       NA    
## ASV4333             NA         NA         NA       NA    
## ASV5547             NA         NA         NA       NA    
## ASV5813             NA         NA         NA       NA    
## ASV8049             NA         NA         NA       NA    
## ASV8661             NA         NA         NA       NA    
## ASV9510             NA         NA         NA       NA    
## ASV1401             NA         NA         NA       NA    
## ASV1417             NA         NA         NA       NA    
## ASV2169             NA         NA         NA       NA    
## ASV5354             NA         NA         NA       NA    
## ASV5379             NA         NA         NA       NA    
## ASV6078             NA         NA         NA       NA    
## ASV6417             NA         NA         NA       NA    
## ASV8304             NA         NA         NA       NA    
## ASV8766             NA         NA         NA       NA    
## ASV10861            NA         NA         NA       NA    
## ASV2057             NA         NA         NA       NA    
## ASV4499             NA         NA         NA       NA    
## ASV7415             NA         NA         NA       NA    
## ASV2475             NA         NA         NA       NA    
## ASV3517             NA         NA         NA       NA    
## ASV1864             NA         NA         NA       NA    
## ASV2756             NA         NA         NA       NA    
## ASV0778             NA         NA         NA       NA    
## ASV3201             NA         NA         NA       NA    
## ASV3358             NA         NA         NA       NA    
## ASV5681             NA         NA         NA       NA    
## ASV7256             NA         NA         NA       NA    
## ASV1704             NA         NA         NA       NA    
## ASV4445             NA         NA         NA       NA    
## ASV8649             NA         NA         NA       NA    
## ASV0597             NA         NA         NA       NA    
## ASV0861             NA         NA         NA       NA    
## ASV2423             NA         NA         NA       NA    
## ASV1548             NA         NA         NA       NA    
## ASV2564             NA         NA         NA       NA    
## ASV2999             NA         NA         NA       NA    
## ASV4543             NA         NA         NA       NA    
## ASV8452             NA         NA         NA       NA    
## ASV17287            NA         NA         NA       NA    
## ASV3503             NA         NA         NA       NA    
## ASV4727             NA         NA         NA       NA    
## ASV5995             NA         NA         NA       NA    
## ASV1665             NA         NA         NA       NA    
## ASV2690             NA         NA         NA       NA    
## ASV2823             NA         NA         NA       NA    
## ASV5241             NA         NA         NA       NA    
## ASV5473             NA         NA         NA       NA    
## ASV2785             NA         NA         NA       NA    
## ASV6645             NA         NA         NA       NA    
## ASV0562             NA         NA         NA       NA    
## ASV1163             NA         NA         NA       NA    
## ASV1825             NA         NA         NA       NA    
## ASV3795             NA         NA         NA       NA    
## ASV3869             NA         NA         NA       NA    
## ASV4330             NA         NA         NA       NA    
## ASV6754             NA         NA         NA       NA    
## ASV4598             NA         NA         NA       NA    
## ASV2100             NA         NA         NA       NA    
## ASV3518             NA         NA         NA       NA    
## ASV3823             NA         NA         NA       NA    
## ASV7357             NA         NA         NA       NA    
## ASV7403             NA         NA         NA       NA    
## ASV2934             NA         NA         NA       NA    
## ASV5277             NA         NA         NA       NA    
## ASV0281             NA         NA         NA       NA    
## ASV11181            NA         NA         NA       NA    
## ASV0254             NA         NA         NA       NA    
## ASV0201             NA         NA         NA       NA    
## ASV3656             NA         NA         NA       NA    
## ASV7994             NA         NA         NA       NA    
## ASV3584             NA         NA         NA       NA    
## ASV2157             NA         NA         NA       NA    
## ASV2935             NA         NA         NA       NA    
## ASV9024             NA         NA         NA       NA    
## ASV7711             NA         NA         NA       NA    
## ASV11330            NA         NA         NA       NA    
## ASV1875             NA         NA         NA       NA    
## ASV5861             NA         NA         NA       NA    
## ASV11562            NA         NA         NA       NA    
## ASV18559            NA         NA         NA       NA    
## ASV4384             NA         NA         NA       NA    
## ASV1302             NA         NA         NA       NA    
## ASV4673             NA         NA         NA       NA    
## ASV1956             NA         NA         NA       NA    
## ASV3286             NA         NA         NA       NA    
## ASV4866             NA         NA         NA       NA    
## ASV3129             NA         NA         NA       NA    
## ASV4104             NA         NA         NA       NA    
## ASV8983             NA         NA         NA       NA    
## ASV2201             NA         NA         NA       NA    
## ASV3055             NA         NA         NA       NA    
## ASV0534             NA         NA         NA       NA    
## ASV1019             NA         NA         NA       NA    
## ASV18482            NA         NA         NA       NA    
## ASV2694             NA         NA         NA       NA    
## ASV3412             NA         NA         NA       NA    
## ASV4174             NA         NA         NA       NA    
## ASV4281             NA         NA         NA       NA    
## ASV4949             NA         NA         NA       NA    
## ASV5881             NA         NA         NA       NA    
## ASV6299             NA         NA         NA       NA    
## ASV0676             NA         NA         NA       NA    
## ASV1066             NA         NA         NA       NA    
## ASV1300             NA         NA         NA       NA    
## ASV6455             NA         NA         NA       NA    
## ASV3455             NA         NA         NA       NA    
## ASV6531             NA         NA         NA       NA    
## ASV0490             NA         NA         NA       NA    
## ASV2588             NA         NA         NA       NA    
## ASV5364             NA         NA         NA       NA    
## ASV0981             NA         NA         NA       NA    
## ASV1563             NA         NA         NA       NA    
## ASV0376             NA         NA         NA       NA    
## ASV7308             NA         NA         NA       NA    
## ASV4817             NA         NA         NA       NA    
## ASV8716             NA         NA         NA       NA    
## ASV1849             NA         NA         NA       NA    
## ASV9423             NA         NA         NA       NA    
## ASV7690             NA         NA         NA       NA    
## ASV4901             NA         NA         NA       NA    
## ASV1830             NA         NA         NA       NA    
## ASV2316             NA         NA         NA       NA    
## ASV0693             NA         NA         NA       NA    
## ASV1243             NA         NA         NA       NA    
## ASV3867             NA         NA         NA       NA    
## ASV7932             NA         NA         NA       NA    
## ASV12608            NA         NA         NA       NA    
## ASV1661             NA         NA         NA       NA    
## ASV3957             NA         NA         NA       NA    
## ASV0830             NA         NA         NA       NA    
## ASV2078             NA         NA         NA       NA    
## ASV13932            NA         NA         NA       NA    
## ASV5300             NA         NA         NA       NA    
## ASV1014             NA         NA         NA       NA    
## ASV13059            NA         NA         NA       NA    
## ASV4340             NA         NA         NA       NA    
## ASV5591             NA         NA         NA       NA    
## ASV6040             NA         NA         NA       NA    
## ASV3904             NA         NA         NA       NA    
## ASV2267             NA         NA         NA       NA    
## ASV0573             NA         NA         NA       NA    
## ASV0851             NA         NA         NA       NA    
## ASV7805             NA         NA         NA       NA    
## ASV3379             NA         NA         NA       NA    
## ASV0825             NA         NA         NA       NA    
## ASV2461             NA         NA         NA       NA    
## ASV2783             NA         NA         NA       NA    
## ASV0925             NA         NA         NA       NA    
## ASV7023             NA         NA         NA       NA    
## ASV5319             NA         NA         NA       NA    
## ASV3213             NA         NA         NA       NA    
## ASV3748             NA         NA         NA       NA    
## ASV5491             NA         NA         NA       NA    
## ASV7931             NA         NA         NA       NA    
## ASV12767            NA         NA         NA       NA    
## ASV6389             NA         NA         NA       NA    
## ASV14867            NA         NA         NA       NA    
## ASV5105             NA         NA         NA       NA    
## ASV15927            NA         NA         NA       NA    
## ASV2004             NA         NA         NA       NA    
## ASV5554             NA         NA         NA       NA    
## ASV10929            NA         NA         NA       NA    
## ASV12778            NA         NA         NA       NA    
## ASV14006            NA         NA         NA       NA    
## ASV1603             NA         NA         NA       NA    
## ASV11948            NA         NA         NA       NA    
## ASV12912            NA         NA         NA       NA    
## ASV13147            NA         NA         NA       NA    
## ASV14761            NA         NA         NA       NA    
## ASV8521             NA         NA         NA       NA    
## ASV8581             NA         NA         NA       NA    
## ASV9875             NA         NA         NA       NA    
## ASV9986             NA         NA         NA       NA    
## ASV2376             NA         NA         NA       NA    
## ASV17535            NA         NA         NA       NA    
## ASV14330            NA         NA         NA       NA    
## ASV1333             NA         NA         NA       NA    
## ASV2498             NA         NA         NA       NA    
## ASV6352             NA         NA         NA       NA    
## ASV8601             NA         NA         NA       NA    
## ASV9776             NA         NA         NA       NA    
## ASV1916             NA         NA         NA       NA    
## ASV1555             NA         NA         NA       NA    
## ASV2499             NA         NA         NA       NA    
## ASV0703             NA         NA         NA       NA    
## ASV2047             NA         NA         NA       NA    
## ASV5492             NA         NA         NA       NA    
## ASV6549             NA         NA         NA       NA    
## ASV7757             NA         NA         NA       NA    
## ASV0173             NA         NA         NA       NA    
## ASV1248             NA         NA         NA       NA    
## ASV6502             NA         NA         NA       NA    
## ASV9844             NA         NA         NA       NA    
## ASV3903             NA         NA         NA       NA    
## ASV8199             NA         NA         NA       NA    
## ASV3309             NA         NA         NA       NA    
## ASV5826             NA         NA         NA       NA    
## ASV1480             NA         NA         NA       NA    
## ASV3090             NA         NA         NA       NA    
## ASV0758             NA         NA         NA       NA    
## ASV0811             NA         NA         NA       NA    
## ASV2653             NA         NA         NA       NA    
## ASV0978             NA         NA         NA       NA    
## ASV6640             NA         NA         NA       NA    
## ASV3423             NA         NA         NA       NA    
## ASV0617             NA         NA         NA       NA    
## ASV14947            NA         NA         NA       NA    
## ASV18367            NA         NA         NA       NA    
## ASV4574             NA         NA         NA       NA    
## ASV10514            NA         NA         NA       NA    
## ASV11779            NA         NA         NA       NA    
## ASV7528             NA         NA         NA       NA    
## ASV13153            NA         NA         NA       NA    
## ASV7858             NA         NA         NA       NA    
## ASV8722             NA         NA         NA       NA    
## ASV6585             NA         NA         NA       NA    
## ASV3311             NA         NA         NA       NA    
## ASV2469             NA         NA         NA       NA    
## ASV11340            NA         NA         NA       NA    
## ASV1718             NA         NA         NA       NA    
## ASV2117             NA         NA         NA       NA    
## ASV8252             NA         NA         NA       NA    
## ASV8533             NA         NA         NA       NA    
## ASV9507             NA         NA         NA       NA    
## ASV0706             NA         NA         NA       NA    
## ASV10312            NA         NA         NA       NA    
## ASV10696            NA         NA         NA       NA    
## ASV11203            NA         NA         NA       NA    
## ASV12147            NA         NA         NA       NA    
## ASV4602             NA         NA         NA       NA    
## ASV5568             NA         NA         NA       NA    
## ASV6777             NA         NA         NA       NA    
## ASV8749             NA         NA         NA       NA    
## ASV4780             NA         NA         NA       NA    
## ASV10116            NA         NA         NA       NA    
## ASV2907             NA         NA         NA       NA    
## ASV5165             NA         NA         NA       NA    
## ASV6061             NA         NA         NA       NA    
## ASV8082             NA         NA         NA       NA    
## ASV7696             NA         NA         NA       NA    
## ASV0550             NA         NA         NA       NA    
## ASV7745             NA         NA         NA       NA    
## ASV3607             NA         NA         NA       NA    
## ASV3877             NA         NA         NA       NA    
## ASV7667             NA         NA         NA       NA    
## ASV9293             NA         NA         NA       NA    
## ASV11653            NA         NA         NA       NA    
## ASV12850            NA         NA         NA       NA    
## ASV13104            NA         NA         NA       NA    
## ASV14208            NA         NA         NA       NA    
## ASV1552             NA         NA         NA       NA    
## ASV2501             NA         NA         NA       NA    
## ASV2893             NA         NA         NA       NA    
## ASV3084             NA         NA         NA       NA    
## ASV3599             NA         NA         NA       NA    
## ASV3868             NA         NA         NA       NA    
## ASV3917             NA         NA         NA       NA    
## ASV5695             NA         NA         NA       NA    
## ASV0131             NA         NA         NA       NA    
## ASV2847             NA         NA         NA       NA    
## ASV6875             NA         NA         NA       NA    
## ASV1547             NA         NA         NA       NA    
## ASV1501             NA         NA         NA       NA    
## ASV3876             NA         NA         NA       NA    
## ASV3456             NA         NA         NA       NA    
## ASV1194             NA         NA         NA       NA    
## ASV2135             NA         NA         NA       NA    
## ASV1352             NA         NA         NA       NA    
## ASV3208             NA         NA         NA       NA    
## ASV1164             NA         NA         NA       NA    
## ASV3492             NA         NA         NA       NA    
## ASV1601             NA         NA         NA       NA    
## ASV5347             NA         NA         NA       NA    
## ASV0293             NA         NA         NA       NA    
## ASV1509             NA         NA         NA       NA    
## ASV2801             NA         NA         NA       NA    
## ASV2873             NA         NA         NA       NA    
## ASV2162             NA         NA         NA       NA    
## ASV0462             NA         NA         NA       NA    
## ASV5367             NA         NA         NA       NA    
## ASV2715             NA         NA         NA       NA    
## ASV0371             NA         NA         NA       NA    
## ASV8090             NA         NA         NA       NA    
## ASV6320             NA         NA         NA       NA    
## ASV2562             NA         NA         NA       NA    
## ASV1505             NA         NA         NA       NA    
## ASV4924             NA         NA         NA       NA    
## ASV1437             NA         NA         NA       NA    
## ASV3816             NA         NA         NA       NA    
## ASV1969             NA         NA         NA       NA    
## ASV3146             NA         NA         NA       NA    
## ASV0321             NA         NA         NA       NA    
## ASV1020             NA         NA         NA       NA    
## ASV4138             NA         NA         NA       NA    
## ASV0329             NA         NA         NA       NA    
## ASV10647            NA         NA         NA       NA    
## ASV3389             NA         NA         NA       NA    
## ASV6880             NA         NA         NA       NA    
## ASV2624             NA         NA         NA       NA    
## ASV3686             NA         NA         NA       NA    
## ASV12302            NA         NA         NA       NA    
## ASV1184             NA         NA         NA       NA    
## ASV3533             NA         NA         NA       NA    
## ASV1735             NA         NA         NA       NA    
## ASV0483             NA         NA         NA       NA    
## ASV0928             NA         NA         NA       NA    
## ASV12254            NA         NA         NA       NA    
## ASV16025            NA         NA         NA       NA    
## ASV3070             NA         NA         NA       NA    
## ASV1850             NA         NA         NA       NA    
## ASV8946             NA         NA         NA       NA    
## ASV1536             NA         NA         NA       NA    
## ASV4151             NA         NA         NA       NA    
## ASV4585             NA         NA         NA       NA    
## ASV4921             NA         NA         NA       NA    
## ASV6172             NA         NA         NA       NA    
## ASV6375             NA         NA         NA       NA    
## ASV6501             NA         NA         NA       NA    
## ASV17095            NA         NA         NA       NA    
## ASV3679             NA         NA         NA       NA    
## ASV5750             NA         NA         NA       NA    
## ASV5922             NA         NA         NA       NA    
## ASV7323             NA         NA         NA       NA    
## ASV8515             NA         NA         NA       NA    
## ASV8753             NA         NA         NA       NA    
## ASV9197             NA         NA         NA       NA    
## ASV1778             NA         NA         NA       NA    
## ASV1241             NA         NA         NA       NA    
## ASV1717             NA         NA         NA       NA    
## ASV1112             NA         NA         NA       NA    
## ASV3994             NA         NA         NA       NA    
## ASV5511             NA         NA         NA       NA    
## ASV8706             NA         NA         NA       NA    
## ASV3049             NA         NA         NA       NA    
## ASV4332             NA         NA         NA       NA    
## ASV7411             NA         NA         NA       NA    
## ASV7475             NA         NA         NA       NA    
## ASV8988             NA         NA         NA       NA    
## ASV0688             NA         NA         NA       NA    
## ASV1946             NA         NA         NA       NA    
## ASV3150             NA         NA         NA       NA    
## ASV3508             NA         NA         NA       NA    
## ASV3863             NA         NA         NA       NA    
## ASV4544             NA         NA         NA       NA    
## ASV4567             NA         NA         NA       NA    
## ASV4855             NA         NA         NA       NA    
## ASV4872             NA         NA         NA       NA    
## ASV4881             NA         NA         NA       NA    
## ASV5283             NA         NA         NA       NA    
## ASV5302             NA         NA         NA       NA    
## ASV5909             NA         NA         NA       NA    
## ASV5933             NA         NA         NA       NA    
## ASV6019             NA         NA         NA       NA    
## ASV6043             NA         NA         NA       NA    
## ASV6908             NA         NA         NA       NA    
## ASV7245             NA         NA         NA       NA    
## ASV7249             NA         NA         NA       NA    
## ASV8349             NA         NA         NA       NA    
## ASV7310             NA         NA         NA       NA    
## ASV1893             NA         NA         NA       NA    
## ASV2354             NA         NA         NA       NA    
## ASV3435             NA         NA         NA       NA    
## ASV0480             NA         NA         NA       NA    
## ASV0955             NA         NA         NA       NA    
## ASV10000            NA         NA         NA       NA    
## ASV7215             NA         NA         NA       NA    
## ASV10423            NA         NA         NA       NA    
## ASV6008             NA         NA         NA       NA    
## ASV9330             NA         NA         NA       NA    
## ASV6051             NA         NA         NA       NA    
## ASV1675             NA         NA         NA       NA    
## ASV2043             NA         NA         NA       NA    
## ASV3634             NA         NA         NA       NA    
## ASV4077             NA         NA         NA       NA    
## ASV4754             NA         NA         NA       NA    
## ASV6095             NA         NA         NA       NA    
## ASV6288             NA         NA         NA       NA    
## ASV6507             NA         NA         NA       NA    
## ASV8905             NA         NA         NA       NA    
## ASV9728             NA         NA         NA       NA    
## ASV11144            NA         NA         NA       NA    
## ASV1615             NA         NA         NA       NA    
## ASV2709             NA         NA         NA       NA    
## ASV3003             NA         NA         NA       NA    
## ASV5163             NA         NA         NA       NA    
## ASV6622             NA         NA         NA       NA    
## ASV1076             NA         NA         NA       NA    
## ASV7895             NA         NA         NA       NA    
## ASV10577            NA         NA         NA       NA    
## ASV1272             NA         NA         NA       NA    
## ASV2492             NA         NA         NA       NA    
## ASV5195             NA         NA         NA       NA    
## ASV5267             NA         NA         NA       NA    
## ASV6317             NA         NA         NA       NA    
## ASV2296             NA         NA         NA       NA    
## ASV2290             NA         NA         NA       NA    
## ASV3726             NA         NA         NA       NA    
## ASV1169             NA         NA         NA       NA    
## ASV0189             NA         NA         NA       NA    
## ASV2729             NA         NA         NA       NA    
## ASV3469             NA         NA         NA       NA    
## ASV0762             NA         NA         NA       NA    
## ASV9001             NA         NA         NA       NA    
## ASV14604            NA         NA         NA       NA    
## ASV7439             NA         NA         NA       NA    
## ASV8625             NA         NA         NA       NA    
## ASV11553            NA         NA         NA       NA    
## ASV14440            NA         NA         NA       NA    
## ASV16106            NA         NA         NA       NA    
## ASV16110            NA         NA         NA       NA    
## ASV2229             NA         NA         NA       NA    
## ASV3854             NA         NA         NA       NA    
## ASV5512             NA         NA         NA       NA    
## ASV5939             NA         NA         NA       NA    
## ASV6676             NA         NA         NA       NA    
## ASV8381             NA         NA         NA       NA    
## ASV2735             NA         NA         NA       NA    
## ASV9816             NA         NA         NA       NA    
## ASV1382             NA         NA         NA       NA    
## ASV1408             NA         NA         NA       NA    
## ASV4902             NA         NA         NA       NA    
## ASV5600             NA         NA         NA       NA    
## ASV0815             NA         NA         NA       NA    
## ASV11867            NA         NA         NA       NA    
## ASV16064            NA         NA         NA       NA    
## ASV2250             NA         NA         NA       NA    
## ASV2417             NA         NA         NA       NA    
## ASV2807             NA         NA         NA       NA    
## ASV3224             NA         NA         NA       NA    
## ASV4115             NA         NA         NA       NA    
## ASV4876             NA         NA         NA       NA    
## ASV5291             NA         NA         NA       NA    
## ASV5834             NA         NA         NA       NA    
## ASV6896             NA         NA         NA       NA    
## ASV7292             NA         NA         NA       NA    
## ASV7924             NA         NA         NA       NA    
## ASV0710             NA         NA         NA       NA    
## ASV1925             NA         NA         NA       NA    
## ASV4247             NA         NA         NA       NA    
## ASV4549             NA         NA         NA       NA    
## ASV4076             NA         NA         NA       NA    
## ASV7063             NA         NA         NA       NA    
## ASV1487             NA         NA         NA       NA    
## ASV1405             NA         NA         NA       NA    
## ASV3851             NA         NA         NA       NA    
## ASV0896             NA         NA         NA       NA    
## ASV5581             NA         NA         NA       NA    
## ASV7053             NA         NA         NA       NA    
## ASV7171             NA         NA         NA       NA    
## ASV4017             NA         NA         NA       NA    
## ASV5846             NA         NA         NA       NA    
## ASV0203             NA         NA         NA       NA    
## ASV13271            NA         NA         NA       NA    
## ASV9487             NA         NA         NA       NA    
## ASV2056             NA         NA         NA       NA    
## ASV16933            NA         NA         NA       NA    
## ASV0360             NA         NA         NA       NA    
## ASV1798             NA         NA         NA       NA    
## ASV17286            NA         NA         NA       NA    
## ASV8175             NA         NA         NA       NA    
## ASV6679             NA         NA         NA       NA    
## ASV6776             NA         NA         NA       NA    
## ASV9062             NA         NA         NA       NA    
## ASV9564             NA         NA         NA       NA    
## ASV6431             NA         NA         NA       NA    
## ASV9940             NA         NA         NA       NA    
## ASV7001             NA         NA         NA       NA    
## ASV3044             NA         NA         NA       NA    
## ASV6684             NA         NA         NA       NA    
## ASV12278            NA         NA         NA       NA    
## ASV3543             NA         NA         NA       NA    
## ASV6397             NA         NA         NA       NA    
## ASV9939             NA         NA         NA       NA    
## ASV9432             NA         NA         NA       NA    
## ASV2630             NA         NA         NA       NA    
## ASV2175             NA         NA         NA       NA    
## ASV4107             NA         NA         NA       NA    
## ASV9172             NA         NA         NA       NA    
## ASV3141             NA         NA         NA       NA    
## ASV9010             NA         NA         NA       NA    
## ASV2550             NA         NA         NA       NA    
## ASV5845             NA         NA         NA       NA    
## ASV3998             NA         NA         NA       NA    
## ASV1389             NA         NA         NA       NA    
## ASV0615             NA         NA         NA       NA    
## ASV9127             NA         NA         NA       NA    
## ASV1190             NA         NA         NA       NA    
## ASV1211             NA         NA         NA       NA    
## ASV1766             NA         NA         NA       NA    
## ASV2337             NA         NA         NA       NA    
## ASV2463             NA         NA         NA       NA    
## ASV2806             NA         NA         NA       NA    
## ASV0439             NA         NA         NA       NA    
## ASV0839             NA         NA         NA       NA    
## ASV14975            NA         NA         NA       NA    
## ASV17712            NA         NA         NA       NA    
## ASV2010             NA         NA         NA       NA    
## ASV2041             NA         NA         NA       NA    
## ASV2124             NA         NA         NA       NA    
## ASV2585             NA         NA         NA       NA    
## ASV3314             NA         NA         NA       NA    
## ASV5051             NA         NA         NA       NA    
## ASV10784            NA         NA         NA       NA    
## ASV3279             NA         NA         NA       NA    
## ASV9498             NA         NA         NA       NA    
## ASV1059             NA         NA         NA       NA    
## ASV13008            NA         NA         NA       NA    
## ASV15803            NA         NA         NA       NA    
## ASV2559             NA         NA         NA       NA    
## ASV2623             NA         NA         NA       NA    
## ASV2802             NA         NA         NA       NA    
## ASV3799             NA         NA         NA       NA    
## ASV5274             NA         NA         NA       NA    
## ASV5835             NA         NA         NA       NA    
## ASV7251             NA         NA         NA       NA    
## ASV7616             NA         NA         NA       NA    
## ASV9576             NA         NA         NA       NA    
## ASV2870             NA         NA         NA       NA    
## ASV3668             NA         NA         NA       NA    
## ASV1633             NA         NA         NA       NA    
## ASV6060             NA         NA         NA       NA    
## ASV6305             NA         NA         NA       NA    
## ASV5164             NA         NA         NA       NA    
## ASV7252             NA         NA         NA       NA    
## ASV9343             NA         NA         NA       NA    
## ASV6835             NA         NA         NA       NA    
## ASV1264             NA         NA         NA       NA    
## ASV0591             NA         NA         NA       NA    
## ASV1351             NA         NA         NA       NA    
## ASV14224            NA         NA         NA       NA    
## ASV1432             NA         NA         NA       NA    
## ASV1559             NA         NA         NA       NA    
## ASV2182             NA         NA         NA       NA    
## ASV2304             NA         NA         NA       NA    
## ASV6838             NA         NA         NA       NA    
## ASV1125             NA         NA         NA       NA    
## ASV17948            NA         NA         NA       NA    
## ASV2609             NA         NA         NA       NA    
## ASV6128             NA         NA         NA       NA    
## ASV1338             NA         NA         NA       NA    
## ASV2136             NA         NA         NA       NA    
## ASV0929             NA         NA         NA       NA    
## ASV3479             NA         NA         NA       NA    
## ASV0886             NA         NA         NA       NA    
## ASV1652             NA         NA         NA       NA    
## ASV1160             NA         NA         NA       NA    
## ASV5260             NA         NA         NA       NA    
## ASV2352             NA         NA         NA       NA    
## ASV0986             NA         NA         NA       NA    
## ASV2021             NA         NA         NA       NA    
## ASV16599            NA         NA         NA       NA    
## ASV3497             NA         NA         NA       NA    
## ASV1305             NA         NA         NA       NA    
## ASV0927             NA         NA         NA       NA    
## ASV0647             NA         NA         NA       NA    
## ASV1832             NA         NA         NA       NA    
## ASV1277             NA         NA         NA       NA    
## ASV22332            NA         NA         NA       NA    
## ASV10080            NA         NA         NA       NA    
## ASV14157            NA         NA         NA       NA    
## ASV15829            NA         NA         NA       NA    
## ASV3609             NA         NA         NA       NA    
## ASV5737             NA         NA         NA       NA    
## ASV1474             NA         NA         NA       NA    
## ASV2028             NA         NA         NA       NA    
## ASV0818             NA         NA         NA       NA    
## ASV0505             NA         NA         NA       NA    
## ASV1813             NA         NA         NA       NA    
## ASV0512             NA         NA         NA       NA    
## ASV5374             NA         NA         NA       NA    
## ASV2927             NA         NA         NA       NA    
## ASV3596             NA         NA         NA       NA    
## ASV1137             NA         NA         NA       NA    
## ASV4541             NA         NA         NA       NA    
## ASV9872             NA         NA         NA       NA    
## ASV0359             NA         NA         NA       NA    
## ASV0720             NA         NA         NA       NA    
## ASV10545            NA         NA         NA       NA    
## ASV13384            NA         NA         NA       NA    
## ASV1456             NA         NA         NA       NA    
## ASV1751             NA         NA         NA       NA    
## ASV18419            NA         NA         NA       NA    
## ASV2970             NA         NA         NA       NA    
## ASV4215             NA         NA         NA       NA    
## ASV4742             NA         NA         NA       NA    
## ASV5017             NA         NA         NA       NA    
## ASV5139             NA         NA         NA       NA    
## ASV9133             NA         NA         NA       NA    
## ASV9447             NA         NA         NA       NA    
## ASV0842             NA         NA         NA       NA    
## ASV12293            NA         NA         NA       NA    
## ASV1965             NA         NA         NA       NA    
## ASV2005             NA         NA         NA       NA    
## ASV5335             NA         NA         NA       NA    
## ASV6438             NA         NA         NA       NA    
## ASV7798             NA         NA         NA       NA    
## ASV2691             NA         NA         NA       NA    
## ASV9958             NA         NA         NA       NA    
## ASV1512             NA         NA         NA       NA    
## ASV1226             NA         NA         NA       NA    
## ASV2130             NA         NA         NA       NA    
## ASV0874             NA         NA         NA       NA    
## ASV5436             NA         NA         NA       NA    
## ASV0383             NA         NA         NA       NA    
## ASV1882             NA         NA         NA       NA    
## ASV2471             NA         NA         NA       NA    
## ASV4049             NA         NA         NA       NA    
## ASV3014             NA         NA         NA       NA    
## ASV0316             NA         NA         NA       NA    
## ASV1621             NA         NA         NA       NA    
## ASV13266            NA         NA         NA       NA    
## ASV1635             NA         NA         NA       NA    
## ASV2042             NA         NA         NA       NA    
## ASV2317             NA         NA         NA       NA    
## ASV3697             NA         NA         NA       NA    
## ASV6404             NA         NA         NA       NA    
## ASV15616            NA         NA         NA       NA    
## ASV10783            NA         NA         NA       NA    
## ASV6912             NA         NA         NA       NA    
## ASV1561             NA         NA         NA       NA    
## ASV4404             NA         NA         NA       NA    
## ASV1110             NA         NA         NA       NA    
## ASV2844             NA         NA         NA       NA    
## ASV5224             NA         NA         NA       NA    
## ASV6300             NA         NA         NA       NA    
## ASV8078             NA         NA         NA       NA    
## ASV9722             NA         NA         NA       NA    
## ASV6911             NA         NA         NA       NA    
## ASV5474             NA         NA         NA       NA    
## ASV2761             NA         NA         NA       NA    
## ASV5943             NA         NA         NA       NA    
## ASV0600             NA         NA         NA       NA    
## ASV0608             NA         NA         NA       NA    
## ASV1586             NA         NA         NA       NA    
## ASV0206             NA         NA         NA       NA    
## ASV4042             NA         NA         NA       NA    
## ASV5304             NA         NA         NA       NA    
## ASV0949             NA         NA         NA       NA    
## ASV1856             NA         NA         NA       NA    
## ASV2584             NA         NA         NA       NA    
## ASV2287             NA         NA         NA       NA    
## ASV2364             NA         NA         NA       NA    
## ASV11481            NA         NA         NA       NA    
## ASV2906             NA         NA         NA       NA    
## ASV0161             NA         NA         NA       NA    
## ASV0062             NA         NA         NA       NA    
## ASV3811             NA         NA         NA       NA    
## ASV0225             NA         NA         NA       NA    
## ASV4672             NA         NA         NA       NA    
## ASV1607             NA         NA         NA       NA    
## ASV3060             NA         NA         NA       NA    
## ASV2275             NA         NA         NA       NA    
## ASV5375             NA         NA         NA       NA    
## ASV0352             NA         NA         NA       NA    
## ASV1107             NA         NA         NA       NA    
## ASV4887             NA         NA         NA       NA    
## ASV2397             NA         NA         NA       NA    
## ASV7541             NA         NA         NA       NA    
## ASV7387             NA         NA         NA       NA    
## ASV1355             NA         NA         NA       NA    
## ASV1764             NA         NA         NA       NA    
## ASV1960             NA         NA         NA       NA    
## ASV0484             NA         NA         NA       NA    
## ASV2487             NA         NA         NA       NA    
## ASV0422             NA         NA         NA       NA    
## ASV0081             NA         NA         NA       NA    
## ASV1341             NA         NA         NA       NA    
## ASV1001             NA         NA         NA       NA    
## ASV0317             NA         NA         NA       NA    
## ASV2728             NA         NA         NA       NA    
## ASV0884             NA         NA         NA       NA    
## ASV0464             NA         NA         NA       NA    
## ASV2963             NA         NA         NA       NA    
## ASV4608             NA         NA         NA       NA    
## ASV3534             NA         NA         NA       NA    
## ASV0291             NA         NA         NA       NA    
## ASV0635             NA         NA         NA       NA    
## ASV0867             NA         NA         NA       NA    
## ASV1206             NA         NA         NA       NA    
## ASV1230             NA         NA         NA       NA    
## ASV1265             NA         NA         NA       NA    
## ASV1291             NA         NA         NA       NA    
## ASV1524             NA         NA         NA       NA    
## ASV2153             NA         NA         NA       NA    
## ASV2714             NA         NA         NA       NA    
## ASV4246             NA         NA         NA       NA    
## ASV0945             NA         NA         NA       NA    
## ASV2380             NA         NA         NA       NA    
## ASV0214             NA         NA         NA       NA    
## ASV10461            NA         NA         NA       NA    
## ASV4177             NA         NA         NA       NA    
## ASV0237             NA         NA         NA       NA    
## ASV11323            NA         NA         NA       NA    
## ASV2232             NA         NA         NA       NA    
## ASV0115             NA         NA         NA       NA    
## ASV1171             NA         NA         NA       NA    
## ASV1942             NA         NA         NA       NA    
## ASV1889             NA         NA         NA       NA    
## ASV0920             NA         NA         NA       NA    
## ASV1805             NA         NA         NA       NA    
## ASV1712             NA         NA         NA       NA    
## ASV1458             NA         NA         NA       NA    
## ASV1985             NA         NA         NA       NA    
## ASV2960             NA         NA         NA       NA    
## ASV5207             NA         NA         NA       NA    
## ASV8548             NA         NA         NA       NA    
## ASV0449             NA         NA         NA       NA    
## ASV0609             NA         NA         NA       NA    
## ASV1038             NA         NA         NA       NA    
## ASV1145             NA         NA         NA       NA    
## ASV15767            NA         NA         NA       NA    
## ASV1630             NA         NA         NA       NA    
## ASV1911             NA         NA         NA       NA    
## ASV1950             NA         NA         NA       NA    
## ASV2583             NA         NA         NA       NA    
## ASV2853             NA         NA         NA       NA    
## ASV2948             NA         NA         NA       NA    
## ASV3116             NA         NA         NA       NA    
## ASV3160             NA         NA         NA       NA    
## ASV3354             NA         NA         NA       NA    
## ASV3368             NA         NA         NA       NA    
## ASV3464             NA         NA         NA       NA    
## ASV3577             NA         NA         NA       NA    
## ASV3746             NA         NA         NA       NA    
## ASV3942             NA         NA         NA       NA    
## ASV4000             NA         NA         NA       NA    
## ASV4207             NA         NA         NA       NA    
## ASV4261             NA         NA         NA       NA    
## ASV4466             NA         NA         NA       NA    
## ASV4487             NA         NA         NA       NA    
## ASV4572             NA         NA         NA       NA    
## ASV4718             NA         NA         NA       NA    
## ASV4757             NA         NA         NA       NA    
## ASV4929             NA         NA         NA       NA    
## ASV5611             NA         NA         NA       NA    
## ASV5614             NA         NA         NA       NA    
## ASV5898             NA         NA         NA       NA    
## ASV7627             NA         NA         NA       NA    
## ASV3105             NA         NA         NA       NA    
## ASV4762             NA         NA         NA       NA    
## ASV5622             NA         NA         NA       NA    
## ASV7129             NA         NA         NA       NA    
## ASV12138            NA         NA         NA       NA    
## ASV1687             NA         NA         NA       NA    
## ASV2187             NA         NA         NA       NA    
## ASV2204             NA         NA         NA       NA    
## ASV2914             NA         NA         NA       NA    
## ASV3297             NA         NA         NA       NA    
## ASV3310             NA         NA         NA       NA    
## ASV3677             NA         NA         NA       NA    
## ASV4508             NA         NA         NA       NA    
## ASV6236             NA         NA         NA       NA    
## ASV6285             NA         NA         NA       NA    
## ASV7576             NA         NA         NA       NA    
## ASV7917             NA         NA         NA       NA    
## ASV9353             NA         NA         NA       NA    
## ASV1656             NA         NA         NA       NA    
## ASV0280             NA         NA         NA       NA    
## ASV4747             NA         NA         NA       NA    
## ASV2108             NA         NA         NA       NA    
## ASV0885             NA         NA         NA       NA    
## ASV2538             NA         NA         NA       NA    
## ASV0968             NA         NA         NA       NA    
## ASV1229             NA         NA         NA       NA    
## ASV13306            NA         NA         NA       NA    
## ASV13952            NA         NA         NA       NA    
## ASV14631            NA         NA         NA       NA    
## ASV2119             NA         NA         NA       NA    
## ASV2450             NA         NA         NA       NA    
## ASV2656             NA         NA         NA       NA    
## ASV2942             NA         NA         NA       NA    
## ASV3302             NA         NA         NA       NA    
## ASV6515             NA         NA         NA       NA    
## ASV6674             NA         NA         NA       NA    
## ASV7296             NA         NA         NA       NA    
## ASV7903             NA         NA         NA       NA    
## ASV7943             NA         NA         NA       NA    
## ASV8864             NA         NA         NA       NA    
## ASV9389             NA         NA         NA       NA    
## ASV9869             NA         NA         NA       NA    
## ASV1051             NA         NA         NA       NA    
## ASV13035            NA         NA         NA       NA    
## ASV15744            NA         NA         NA       NA    
## ASV2526             NA         NA         NA       NA    
## ASV1156             NA         NA         NA       NA    
## ASV13562            NA         NA         NA       NA    
## ASV1438             NA         NA         NA       NA    
## ASV2268             NA         NA         NA       NA    
## ASV2797             NA         NA         NA       NA    
## ASV3744             NA         NA         NA       NA    
## ASV8076             NA         NA         NA       NA    
## ASV7055             NA         NA         NA       NA    
## ASV7493             NA         NA         NA       NA    
## ASV1201             NA         NA         NA       NA    
## ASV5736             NA         NA         NA       NA    
## ASV0558             NA         NA         NA       NA    
## ASV14399            NA         NA         NA       NA    
## ASV2992             NA         NA         NA       NA    
## ASV4303             NA         NA         NA       NA    
## ASV0565             NA         NA         NA       NA    
## ASV0977             NA         NA         NA       NA    
## ASV0140             NA         NA         NA       NA    
## ASV14421            NA         NA         NA       NA    
## ASV16909            NA         NA         NA       NA    
## ASV3762             NA         NA         NA       NA    
## ASV7141             NA         NA         NA       NA    
## ASV3291             NA         NA         NA       NA    
## ASV10440            NA         NA         NA       NA    
## ASV10802            NA         NA         NA       NA    
## ASV1698             NA         NA         NA       NA    
## ASV2121             NA         NA         NA       NA    
## ASV3549             NA         NA         NA       NA    
## ASV6379             NA         NA         NA       NA    
## ASV6824             NA         NA         NA       NA    
## ASV8254             NA         NA         NA       NA    
## ASV9951             NA         NA         NA       NA    
## ASV1515             NA         NA         NA       NA    
## ASV4327             NA         NA         NA       NA    
## ASV0341             NA         NA         NA       NA    
## ASV5562             NA         NA         NA       NA    
## ASV1412             NA         NA         NA       NA    
## ASV0154             NA         NA         NA       NA    
## ASV3163             NA         NA         NA       NA    
## ASV1782             NA         NA         NA       NA    
## ASV3993             NA         NA         NA       NA    
## ASV3164             NA         NA         NA       NA    
## ASV1024             NA         NA         NA       NA    
## ASV0771             NA         NA         NA       NA    
## ASV2223             NA         NA         NA       NA    
## ASV1638             NA         NA         NA       NA    
## ASV0232             NA         NA         NA       NA    
## ASV6771             NA         NA         NA       NA    
## ASV4243             NA         NA         NA       NA    
## ASV0162             NA         NA         NA       NA    
## ASV0049             NA         NA         NA       NA    
## ASV4697             NA         NA         NA       NA    
## ASV12326            NA         NA         NA       NA    
## ASV12586            NA         NA         NA       NA    
## ASV1879             NA         NA         NA       NA    
## ASV2864             NA         NA         NA       NA    
## ASV3111             NA         NA         NA       NA    
## ASV5633             NA         NA         NA       NA    
## ASV5864             NA         NA         NA       NA    
## ASV6364             NA         NA         NA       NA    
## ASV1598             NA         NA         NA       NA    
## ASV2649             NA         NA         NA       NA    
## ASV4664             NA         NA         NA       NA    
## ASV2654             NA         NA         NA       NA    
## ASV6636             NA         NA         NA       NA    
## ASV3334             NA         NA         NA       NA    
## ASV0046             NA         NA         NA       NA    
## ASV0661             NA         NA         NA       NA    
## ASV0774             NA         NA         NA       NA    
## ASV3815             NA         NA         NA       NA    
## ASV0575             NA         NA         NA       NA    
## ASV1953             NA         NA         NA       NA    
## ASV0610             NA         NA         NA       NA    
## ASV0245             NA         NA         NA       NA    
## ASV3805             NA         NA         NA       NA    
## ASV1182             NA         NA         NA       NA    
## ASV1941             NA         NA         NA       NA    
## ASV0080             NA         NA         NA       NA    
## ASV1033             NA         NA         NA       NA    
## ASV5330             NA         NA         NA       NA    
## ASV9702             NA         NA         NA       NA    
## ASV0358             NA         NA         NA       NA    
## ASV2225             NA         NA         NA       NA    
## ASV2606             NA         NA         NA       NA    
## ASV3510             NA         NA         NA       NA    
## ASV3069             NA         NA         NA       NA    
## ASV3849             NA         NA         NA       NA    
## ASV1810             NA         NA         NA       NA    
## ASV2046             NA         NA         NA       NA    
## ASV2451             NA         NA         NA       NA    
## ASV4047             NA         NA         NA       NA    
## ASV7402             NA         NA         NA       NA    
## ASV8250             NA         NA         NA       NA    
## ASV3468             NA         NA         NA       NA    
## ASV3521             NA         NA         NA       NA    
## ASV6363             NA         NA         NA       NA    
## ASV6444             NA         NA         NA       NA    
## ASV8231             NA         NA         NA       NA    
## ASV0196             NA         NA         NA       NA    
## ASV12801            NA         NA         NA       NA    
## ASV12906            NA         NA         NA       NA    
## ASV13040            NA         NA         NA       NA    
## ASV1313             NA         NA         NA       NA    
## ASV14008            NA         NA         NA       NA    
## ASV1546             NA         NA         NA       NA    
## ASV1637             NA         NA         NA       NA    
## ASV17076            NA         NA         NA       NA    
## ASV2061             NA         NA         NA       NA    
## ASV2177             NA         NA         NA       NA    
## ASV2943             NA         NA         NA       NA    
## ASV3020             NA         NA         NA       NA    
## ASV30254            NA         NA         NA       NA    
## ASV3219             NA         NA         NA       NA    
## ASV3352             NA         NA         NA       NA    
## ASV3355             NA         NA         NA       NA    
## ASV3377             NA         NA         NA       NA    
## ASV3449             NA         NA         NA       NA    
## ASV3893             NA         NA         NA       NA    
## ASV4326             NA         NA         NA       NA    
## ASV5016             NA         NA         NA       NA    
## ASV5152             NA         NA         NA       NA    
## ASV5666             NA         NA         NA       NA    
## ASV5802             NA         NA         NA       NA    
## ASV6070             NA         NA         NA       NA    
## ASV6488             NA         NA         NA       NA    
## ASV6562             NA         NA         NA       NA    
## ASV6930             NA         NA         NA       NA    
## ASV7243             NA         NA         NA       NA    
## ASV7506             NA         NA         NA       NA    
## ASV7553             NA         NA         NA       NA    
## ASV8064             NA         NA         NA       NA    
## ASV8434             NA         NA         NA       NA    
## ASV8858             NA         NA         NA       NA    
## ASV2600             NA         NA         NA       NA    
## ASV3398             NA         NA         NA       NA    
## ASV4584             NA         NA         NA       NA    
## ASV4864             NA         NA         NA       NA    
## ASV0082             NA         NA         NA       NA    
## ASV9626             NA         NA         NA       NA    
## ASV1617             NA         NA         NA       NA    
## ASV2765             NA         NA         NA       NA    
## ASV2167             NA         NA         NA       NA    
## ASV1628             NA         NA         NA       NA    
## ASV3260             NA         NA         NA       NA    
## ASV3645             NA         NA         NA       NA    
## ASV6057             NA         NA         NA       NA    
## ASV0662             NA         NA         NA       NA    
## ASV4267             NA         NA         NA       NA    
## ASV1070             NA         NA         NA       NA    
## ASV0633             NA         NA         NA       NA    
## ASV0333             NA         NA         NA       NA    
## ASV0966             NA         NA         NA       NA    
## ASV1848             NA         NA         NA       NA    
## ASV13390            NA         NA         NA       NA    
## ASV14901            NA         NA         NA       NA    
## ASV1676             NA         NA         NA       NA    
## ASV1756             NA         NA         NA       NA    
## ASV22537            NA         NA         NA       NA    
## ASV3303             NA         NA         NA       NA    
## ASV4030             NA         NA         NA       NA    
## ASV4871             NA         NA         NA       NA    
## ASV5536             NA         NA         NA       NA    
## ASV5700             NA         NA         NA       NA    
## ASV8957             NA         NA         NA       NA    
## ASV11210            NA         NA         NA       NA    
## ASV7585             NA         NA         NA       NA    
## ASV8596             NA         NA         NA       NA    
## ASV9532             NA         NA         NA       NA    
## ASV4254             NA         NA         NA       NA    
## ASV13299            NA         NA         NA       NA    
## ASV15627            NA         NA         NA       NA    
## ASV6302             NA         NA         NA       NA    
## ASV3040             NA         NA         NA       NA    
## ASV0632             NA         NA         NA       NA    
## ASV3694             NA         NA         NA       NA    
## ASV1592             NA         NA         NA       NA    
## ASV0538             NA         NA         NA       NA    
## ASV0832             NA         NA         NA       NA    
## ASV0727             NA         NA         NA       NA    
## ASV1165             NA         NA         NA       NA    
## ASV1325             NA         NA         NA       NA    
## ASV0819             NA         NA         NA       NA    
## ASV2251             NA         NA         NA       NA    
## ASV0100             NA         NA         NA       NA    
## ASV0444             NA         NA         NA       NA    
## ASV0800             NA         NA         NA       NA    
## ASV2432             NA         NA         NA       NA    
## ASV2883             NA         NA         NA       NA    
## ASV3894             NA         NA         NA       NA    
## ASV2367             NA         NA         NA       NA    
## ASV3724             NA         NA         NA       NA    
## ASV2112             NA         NA         NA       NA    
## ASV3661             NA         NA         NA       NA    
## ASV2096             NA         NA         NA       NA    
## ASV3551             NA         NA         NA       NA    
## ASV11343            NA         NA         NA       NA    
## ASV2051             NA         NA         NA       NA    
## ASV2617             NA         NA         NA       NA    
## ASV0125             NA         NA         NA       NA    
## ASV0372             NA         NA         NA       NA    
## ASV6751             NA         NA         NA       NA    
## ASV10810            NA         NA         NA       NA    
## ASV0461             NA         NA         NA       NA    
## ASV1945             NA         NA         NA       NA    
## ASV0882             NA         NA         NA       NA    
## ASV4040             NA         NA         NA       NA    
## ASV0109             NA         NA         NA       NA    
## ASV0174             NA         NA         NA       NA    
## ASV2851             NA         NA         NA       NA    
## ASV5312             NA         NA         NA       NA    
## ASV9402             NA         NA         NA       NA    
## ASV4870             NA         NA         NA       NA    
## ASV0589             NA         NA         NA       NA    
## ASV1221             NA         NA         NA       NA    
## ASV6028             NA         NA         NA       NA    
## ASV5106             NA         NA         NA       NA    
## ASV4977             NA         NA         NA       NA    
## ASV5715             NA         NA         NA       NA    
## ASV4182             NA         NA         NA       NA    
## ASV2383             NA         NA         NA       NA    
## ASV3985             NA         NA         NA       NA    
## ASV2787             NA         NA         NA       NA    
## ASV6756             NA         NA         NA       NA    
## ASV1634             NA         NA         NA       NA    
## ASV0649             NA         NA         NA       NA    
## ASV1591             NA         NA         NA       NA    
## ASV1854             NA         NA         NA       NA    
## ASV4205             NA         NA         NA       NA    
## ASV3293             NA         NA         NA       NA    
## ASV1631             NA         NA         NA       NA    
## ASV1747             NA         NA         NA       NA    
## ASV5634             NA         NA         NA       NA    
## ASV0965             NA         NA         NA       NA    
## ASV1094             NA         NA         NA       NA    
## ASV2744             NA         NA         NA       NA    
## ASV7212             NA         NA         NA       NA    
## ASV0344             NA         NA         NA       NA    
## ASV11812            NA         NA         NA       NA    
## ASV7867             NA         NA         NA       NA    
## ASV6670             NA         NA         NA       NA    
## ASV10991            NA         NA         NA       NA    
## ASV1281             NA         NA         NA       NA    
## ASV12845            NA         NA         NA       NA    
## ASV1833             NA         NA         NA       NA    
## ASV2211             NA         NA         NA       NA    
## ASV3920             NA         NA         NA       NA    
## ASV4545             NA         NA         NA       NA    
## ASV4710             NA         NA         NA       NA    
## ASV4978             NA         NA         NA       NA    
## ASV9630             NA         NA         NA       NA    
## ASV9797             NA         NA         NA       NA    
## ASV13469            NA         NA         NA       NA    
## ASV14961            NA         NA         NA       NA    
## ASV6259             NA         NA         NA       NA    
## ASV6294             NA         NA         NA       NA    
## ASV6883             NA         NA         NA       NA    
## ASV7041             NA         NA         NA       NA    
## ASV4363             NA         NA         NA       NA    
## ASV1784             NA         NA         NA       NA    
## ASV2140             NA         NA         NA       NA    
## ASV3202             NA         NA         NA       NA    
## ASV6017             NA         NA         NA       NA    
## ASV9129             NA         NA         NA       NA    
## ASV0917             NA         NA         NA       NA    
## ASV10584            NA         NA         NA       NA    
## ASV11218            NA         NA         NA       NA    
## ASV11229            NA         NA         NA       NA    
## ASV11604            NA         NA         NA       NA    
## ASV2103             NA         NA         NA       NA    
## ASV2165             NA         NA         NA       NA    
## ASV2340             NA         NA         NA       NA    
## ASV3738             NA         NA         NA       NA    
## ASV4012             NA         NA         NA       NA    
## ASV4094             NA         NA         NA       NA    
## ASV4454             NA         NA         NA       NA    
## ASV7031             NA         NA         NA       NA    
## ASV7087             NA         NA         NA       NA    
## ASV4159             NA         NA         NA       NA    
## ASV5084             NA         NA         NA       NA    
## ASV6584             NA         NA         NA       NA    
## ASV9614             NA         NA         NA       NA    
## ASV16068            NA         NA         NA       NA    
## ASV2141             NA         NA         NA       NA    
## ASV0395             NA         NA         NA       NA    
## ASV5640             NA         NA         NA       NA    
## ASV2854             NA         NA         NA       NA    
## ASV3825             NA         NA         NA       NA    
## ASV0481             NA         NA         NA       NA    
## ASV3304             NA         NA         NA       NA    
## ASV0445             NA         NA         NA       NA    
## ASV1845             NA         NA         NA       NA    
## ASV3110             NA         NA         NA       NA    
## ---
## Signif. codes:  0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1
## 
## (Dispersion parameter for binomial family taken to be 1)
## 
##     Null deviance:   385.39  on 277  degrees of freedom
## Residual deviance: 11750.23  on   0  degrees of freedom
## AIC: 12306
## 
## Number of Fisher Scoring iterations: 8

Recall from Adv ML: - The n << p here is an underdetermined system. There is not a unique solution. - If standard errors of coefficients are very large, which in this case they are, this is not a stable model.

Recall from Regression Classes and Other Course Notes: - Null Deviance is for a model with no predictors; just the intercept. - Null Deviance measures the goodness of fit of a model with no predictors. - ‘$df.null’ is the degrees of freedom for the null model: n-1 observations

pchisq(logreg$null.deviance, logreg$df.null, lower.tail = FALSE)
## [1] 1.735332e-05
# Bad fit in notes had a p-value of 0.9995629 from Ressler
# good fit would be the opposite
pchisq(logreg$deviance, logreg$df.residual, lower.tail = FALSE)
## [1] 0

1000 from the PCA results in Dim 1 to see if it helps some of the issues in modeling

Start with balanced dataset first because will need to retransform after first 1000.

  • They are in order so can simply take first 1000
# lr_clr_df %>%
#   select(1:1002) -> lr_clr_df_1000 # because of id column and response column

lr_data[,1:1002] -> lr_data_1000
 
  
bind_cols(lr_data_1000[,1:2], 
          lr_data_1000[,-c(1,2)] %>% clr()
            ) -> lr_clr_df_1000

Logistic with Reduced 1000 ASVs

glmnet::glmnet

1000

L2 regularization

y = as.factor(lr_clr_df_1000$Clade)
x = as.matrix(lr_clr_df_1000[,-c(1,2)])

#glimpse(y)
#dim(x)

library(glmnet)
lr_model_1000 <- glmnet(x, y, 
                        family = "binomial", 
                        #alpha = 1 ,# lasso L1 norm
                        alpha = 0 # ridge L2 norm
                )
lr_model_1000
## 
## Call:  glmnet(x = x, y = y, family = "binomial", alpha = 0) 
## 
##       Df  %Dev  Lambda
## 1   1000  0.00 166.200
## 2   1000  1.13 158.700
## 3   1000  1.18 151.400
## 4   1000  1.23 144.600
## 5   1000  1.29 138.000
## 6   1000  1.35 131.700
## 7   1000  1.41 125.700
## 8   1000  1.47 120.000
## 9   1000  1.54 114.600
## 10  1000  1.61 109.400
## 11  1000  1.68 104.400
## 12  1000  1.75  99.640
## 13  1000  1.83  95.110
## 14  1000  1.91  90.790
## 15  1000  2.00  86.660
## 16  1000  2.09  82.720
## 17  1000  2.18  78.960
## 18  1000  2.28  75.370
## 19  1000  2.38  71.950
## 20  1000  2.48  68.680
## 21  1000  2.59  65.560
## 22  1000  2.70  62.580
## 23  1000  2.82  59.730
## 24  1000  2.94  57.020
## 25  1000  3.07  54.420
## 26  1000  3.20  51.950
## 27  1000  3.33  49.590
## 28  1000  3.47  47.340
## 29  1000  3.62  45.180
## 30  1000  3.77  43.130
## 31  1000  3.93  41.170
## 32  1000  4.09  39.300
## 33  1000  4.26  37.510
## 34  1000  4.44  35.810
## 35  1000  4.62  34.180
## 36  1000  4.81  32.630
## 37  1000  5.00  31.140
## 38  1000  5.21  29.730
## 39  1000  5.41  28.380
## 40  1000  5.63  27.090
## 41  1000  5.85  25.860
## 42  1000  6.08  24.680
## 43  1000  6.32  23.560
## 44  1000  6.56  22.490
## 45  1000  6.82  21.470
## 46  1000  7.08  20.490
## 47  1000  7.35  19.560
## 48  1000  7.62  18.670
## 49  1000  7.91  17.820
## 50  1000  8.20  17.010
## 51  1000  8.50  16.240
## 52  1000  8.81  15.500
## 53  1000  9.13  14.800
## 54  1000  9.46  14.120
## 55  1000  9.79  13.480
## 56  1000 10.14  12.870
## 57  1000 10.49  12.280
## 58  1000 10.86  11.730
## 59  1000 11.23  11.190
## 60  1000 11.61  10.680
## 61  1000 12.00  10.200
## 62  1000 12.40   9.735
## 63  1000 12.81   9.292
## 64  1000 13.23   8.870
## 65  1000 13.65   8.467
## 66  1000 14.09   8.082
## 67  1000 14.50   7.715
## 68  1000 14.95   7.364
## 69  1000 15.41   7.029
## 70  1000 15.88   6.710
## 71  1000 16.36   6.405
## 72  1000 16.85   6.114
## 73  1000 17.34   5.836
## 74  1000 17.85   5.571
## 75  1000 18.36   5.317
## 76  1000 18.88   5.076
## 77  1000 19.41   4.845
## 78  1000 19.95   4.625
## 79  1000 20.50   4.415
## 80  1000 21.05   4.214
## 81  1000 21.61   4.022
## 82  1000 22.18   3.840
## 83  1000 22.75   3.665
## 84  1000 23.34   3.498
## 85  1000 23.93   3.339
## 86  1000 24.52   3.188
## 87  1000 25.12   3.043
## 88  1000 25.73   2.904
## 89  1000 26.35   2.772
## 90  1000 26.96   2.646
## 91  1000 27.59   2.526
## 92  1000 28.22   2.411
## 93  1000 28.85   2.302
## 94  1000 29.49   2.197
## 95  1000 30.14   2.097
## 96  1000 30.78   2.002
## 97  1000 31.43   1.911
## 98  1000 32.09   1.824
## 99  1000 32.74   1.741
## 100 1000 33.40   1.662
summary(lr_model_1000)
##            Length Class     Mode     
## a0            100 -none-    numeric  
## beta       100000 dgCMatrix S4       
## df            100 -none-    numeric  
## dim             2 -none-    numeric  
## lambda        100 -none-    numeric  
## dev.ratio     100 -none-    numeric  
## nulldev         1 -none-    numeric  
## npasses         1 -none-    numeric  
## jerr            1 -none-    numeric  
## offset          1 -none-    logical  
## classnames      2 -none-    character
## call            5 -none-    call     
## nobs            1 -none-    numeric
plot(lr_model_1000)

plot(lr_model_1000, xlim = c(0, .1), ylim = c(-0.02, 0.02))

Cross-Validation

cv_results <- cv.glmnet(x, y,
                        family = "binomial",
                        nfolds = 10)
plot(cv_results)

best_lambda_1000 <- lr_model_1000$lambda.min

# Refit the model with the selected lambda
best_model_1000 <- glmnet(x, y, family = "binomial", alpha = 0, lambda = best_lambda_1000)

coefficients(best_model_1000)[,1:3]
## 1001 x 3 sparse Matrix of class "dgCMatrix"
##                        s0            s1            s2
## (Intercept) -1.249001e-16  8.559541e-03  8.966024e-03
## ASV1236      2.313137e-37  1.394100e-03  1.460363e-03
## ASV0421     -1.103570e-37 -6.609057e-04 -6.923665e-04
## ASV0691     -2.330527e-37 -1.364898e-03 -1.429777e-03
## ASV0899      1.300837e-37  8.053254e-04  8.436280e-04
## ASV1004      5.196804e-37  3.138310e-03  3.287476e-03
## ASV1041     -3.153556e-37 -1.915427e-03 -2.006359e-03
## ASV1058      3.238329e-37  1.955540e-03  2.048373e-03
## ASV12542     1.240721e-37  7.404594e-04  7.757174e-04
## ASV1294      2.713433e-37  1.643319e-03  1.721342e-03
## ASV13113     9.227698e-38  5.774566e-04  6.049308e-04
## ASV1318      2.974952e-37  1.800155e-03  1.885561e-03
## ASV2269     -5.011790e-37 -3.052902e-03 -3.196991e-03
## ASV2542      2.166652e-37  1.338551e-03  1.402068e-03
## ASV2660     -2.252494e-37 -1.361489e-03 -1.425811e-03
## ASV2737      4.487411e-38  2.562562e-04  2.686682e-04
## ASV2840      2.859513e-37  1.713695e-03  1.794856e-03
## ASV3053      2.397345e-36  1.442345e-02  1.510463e-02
## ASV3077      8.480135e-38  5.085396e-04  5.326100e-04
## ASV3134      1.549578e-37  9.624004e-04  1.008170e-03
## ASV3140      1.913464e-37  1.177401e-03  1.233147e-03
## ASV3579      6.046585e-38  3.807353e-04  3.989826e-04
## ASV6119     -1.368029e-37 -8.333249e-04 -8.725745e-04
## ASV7557     -2.783073e-37 -1.695289e-03 -1.775006e-03
## ASV8422      6.409379e-38  3.771121e-04  3.952726e-04
## ASV1086     -1.565806e-38 -9.052144e-05 -9.482473e-05
## ASV1310      1.200270e-37  7.246213e-04  7.590342e-04
## ASV15750    -2.058606e-38 -1.245425e-04 -1.303068e-04
## ASV16905    -5.713590e-38 -3.480387e-04 -3.644019e-04
## ASV2033      2.475958e-37  1.523486e-03  1.596089e-03
## ASV2089      1.041249e-37  6.358152e-04  6.656991e-04
## ASV2127      3.997226e-37  2.412485e-03  2.526882e-03
## ASV2725      3.236290e-37  1.938749e-03  2.030791e-03
## ASV2804     -1.183344e-37 -7.208237e-04 -7.546912e-04
## ASV3075      2.672760e-37  1.618234e-03  1.695132e-03
## ASV3327      3.570452e-37  2.193278e-03  2.297819e-03
## ASV3342      2.948194e-37  1.808894e-03  1.894651e-03
## ASV3532     -3.344720e-37 -2.057244e-03 -2.154334e-03
## ASV3600      1.527223e-37  9.304155e-04  9.746890e-04
## ASV4013      2.977252e-37  1.802898e-03  1.888492e-03
## ASV4136      3.320250e-37  1.991843e-03  2.086027e-03
## ASV4195      1.196262e-36  7.286922e-03  7.628608e-03
## ASV4407     -4.679698e-37 -2.850594e-03 -2.984040e-03
## ASV4717      5.230493e-38  2.890044e-04  3.034034e-04
## ASV6794      1.926202e-37  1.133281e-03  1.187377e-03
## ASV8324     -2.397177e-37 -1.460217e-03 -1.528574e-03
## ASV8981     -9.113278e-39 -5.241488e-05 -5.467353e-05
## ASV9859      6.805349e-38  4.340526e-04  4.549901e-04
## ASV0936      1.622018e-38  1.101252e-04  1.150230e-04
## ASV12683    -4.432161e-39 -3.348258e-05 -3.480415e-05
## ASV1293      1.527595e-37  9.213838e-04  9.649394e-04
## ASV13055    -8.706304e-39 -5.125634e-05 -5.329826e-05
## ASV17063    -1.242972e-37 -7.571430e-04 -7.924237e-04
## ASV2228      1.012017e-37  6.164589e-04  6.451370e-04
## ASV2769      9.716036e-39  6.036428e-05  6.358468e-05
## ASV2803      9.455162e-38  5.557170e-04  5.823590e-04
## ASV2896      8.356686e-38  5.108955e-04  5.353061e-04
## ASV3062      8.777758e-38  5.453552e-04  5.718076e-04
## ASV3107      1.667808e-37  1.022760e-03  1.071443e-03
## ASV3265      2.359002e-37  1.422091e-03  1.489316e-03
## ASV3666      1.340054e-39  5.578262e-06  6.164995e-06
## ASV4497      7.160688e-38  4.320072e-04  4.527005e-04
## ASV6914     -1.543954e-38 -1.005464e-04 -1.050622e-04
## ASV0576     -3.112524e-37 -1.843308e-03 -1.930661e-03
## ASV0673      2.198679e-37  1.347284e-03  1.411098e-03
## ASV0772      1.291034e-37  7.816118e-04  8.187864e-04
## ASV0862     -2.458659e-38 -1.335368e-04 -1.397524e-04
## ASV0898      9.047621e-38  5.628762e-04  5.896462e-04
## ASV0910      1.133405e-37  6.981760e-04  7.313287e-04
## ASV0964     -1.222272e-37 -7.309320e-04 -7.655512e-04
## ASV10059     7.868340e-38  4.914020e-04  5.149129e-04
## ASV10263    -1.892670e-37 -1.152897e-03 -1.207113e-03
## ASV1088      1.831116e-37  1.124283e-03  1.177711e-03
## ASV1101      2.225452e-37  1.344589e-03  1.408201e-03
## ASV1183      6.577420e-38  4.050347e-04  4.241337e-04
## ASV11956     6.369100e-38  3.670147e-04  3.846346e-04
## ASV12774     8.458601e-40 -2.760981e-06 -2.782851e-06
## ASV1321      2.821092e-37  1.738417e-03  1.821302e-03
## ASV13793    -1.304459e-37 -7.945951e-04 -8.319266e-04
## ASV14482     3.530656e-39  1.245270e-05  1.315951e-05
## ASV15483     4.778735e-38  2.926410e-04  3.066757e-04
## ASV2062      2.419400e-37  1.470145e-03  1.539617e-03
## ASV2132      2.064836e-37  1.270260e-03  1.330744e-03
## ASV2413      1.933389e-37  1.163967e-03  1.218933e-03
## ASV2490      6.089161e-37  3.629632e-03  3.800919e-03
## ASV2594      6.907828e-38  4.182005e-04  4.380220e-04
## ASV2822     -3.447005e-37 -2.099700e-03 -2.198653e-03
## ASV2863      3.806829e-37  2.288579e-03  2.396155e-03
## ASV2910      1.321773e-37  7.933841e-04  8.310227e-04
## ASV2980      1.250029e-37  7.629922e-04  7.989479e-04
## ASV3307      2.730686e-37  1.663362e-03  1.741518e-03
## ASV3474      1.616732e-37  9.993295e-04  1.046900e-03
## ASV3502      1.993020e-37  1.215917e-03  1.273562e-03
## ASV4236      2.974774e-37  1.785219e-03  1.868809e-03
## ASV4842     -5.297937e-38 -3.388126e-04 -3.549107e-04
## ASV4894     -1.304459e-37 -7.945941e-04 -8.320065e-04
## ASV5290      1.032380e-37  6.295356e-04  6.595440e-04
## ASV5501      5.210114e-38  3.154824e-04  3.303683e-04
## ASV5795      6.306093e-38  3.847774e-04  4.030567e-04
## ASV5987     -3.649535e-37 -2.223066e-03 -2.327849e-03
## ASV6267     -4.113963e-37 -2.505966e-03 -2.623889e-03
## ASV6862      1.746877e-37  1.038615e-03  1.087676e-03
## ASV7145      6.876014e-38  3.965433e-04  4.150898e-04
## ASV7673     -1.304459e-37 -7.945936e-04 -8.319721e-04
## ASV7789      5.210997e-38  3.274531e-04  3.431935e-04
## ASV7809     -3.236514e-39 -1.736248e-05 -1.800547e-05
## ASV8002     -1.647947e-37 -1.003824e-03 -1.051005e-03
## ASV8205      5.628364e-38  3.388780e-04  3.551458e-04
## ASV9155     -4.555355e-38 -2.767566e-04 -2.896835e-04
## ASV9221      4.624289e-39  2.537940e-05  2.689302e-05
## ASV9311     -2.645711e-37 -1.611598e-03 -1.687225e-03
## ASV9557     -1.807136e-37 -1.100792e-03 -1.152363e-03
## ASV9936     -3.649535e-37 -2.223063e-03 -2.327041e-03
## ASV1445      2.371269e-37  1.450023e-03  1.518918e-03
## ASV4232      1.031736e-37  6.378912e-04  6.683295e-04
## ASV6479      1.207169e-38  8.873740e-05  9.324463e-05
## ASV0142     -1.543844e-37 -9.265613e-04 -9.702822e-04
## ASV0378     -9.024721e-39 -4.516801e-05 -4.709691e-05
## ASV1122      2.326086e-37  1.425385e-03  1.493038e-03
## ASV0123     -1.367790e-37 -8.203329e-04 -8.589734e-04
## ASV2064      8.100367e-38  4.752077e-04  4.975054e-04
## ASV4459     -3.271681e-38 -2.043887e-04 -2.139440e-04
## ASV0448      4.831431e-38  3.037807e-04  3.183378e-04
## ASV0397      1.083716e-37  6.630086e-04  6.944923e-04
## ASV0485      1.441358e-37  8.737148e-04  9.150310e-04
## ASV1566      2.270274e-37  1.382816e-03  1.448301e-03
## ASV1365      1.466433e-37  8.876752e-04  9.298099e-04
## ASV1065      2.712034e-37  1.657682e-03  1.736077e-03
## ASV0722     -1.563383e-38 -9.532325e-05 -9.990116e-05
## ASV12660    -1.522608e-37 -9.175453e-04 -9.608047e-04
## ASV0223      2.278950e-38  1.393713e-04  1.459451e-04
## ASV0229      5.560127e-38  3.435098e-04  3.598016e-04
## ASV0877      7.526500e-39  3.654254e-05  3.864099e-05
## ASV0983      1.469405e-37  8.874245e-04  9.293185e-04
## ASV0626     -1.441585e-38 -7.438319e-05 -7.746473e-05
## ASV4146     -7.067638e-39 -4.722935e-05 -4.912421e-05
## ASV4175     -1.727823e-37 -1.060025e-03 -1.109946e-03
## ASV2082     -7.687000e-38 -4.867694e-04 -5.104888e-04
## ASV2272      7.987959e-38  4.842595e-04  5.072806e-04
## ASV2245     -1.256358e-37 -7.717385e-04 -8.080287e-04
## ASV0590     -9.858070e-38 -6.263833e-04 -6.567938e-04
## ASV0217     -1.844218e-38 -9.253090e-05 -9.660567e-05
## ASV0416      1.038749e-37  6.145003e-04  6.432341e-04
## ASV1056      1.101317e-37  6.813088e-04  7.138788e-04
## ASV7777     -1.667846e-37 -1.028871e-03 -1.077234e-03
## ASV0455      2.146648e-38  1.313842e-04  1.374896e-04
## ASV0604      6.562340e-38  4.110815e-04  4.309004e-04
## ASV6100     -1.181295e-37 -7.293995e-04 -7.637175e-04
## ASV11359    -2.691605e-37 -1.642709e-03 -1.719690e-03
## ASV6604      4.713687e-38  2.918813e-04  3.058769e-04
## ASV5004     -7.566846e-38 -4.658588e-04 -4.875782e-04
## ASV1483     -4.705807e-38 -2.921389e-04 -3.056769e-04
## ASV9773     -1.185726e-37 -7.294351e-04 -7.637104e-04
## ASV4059      8.416279e-38  5.303008e-04  5.559560e-04
## ASV1193      1.464229e-37  8.917042e-04  9.339957e-04
## ASV4610     -2.376196e-38 -1.312592e-04 -1.370502e-04
## ASV0742     -3.662341e-38 -2.092892e-04 -2.186451e-04
## ASV1502      6.398060e-39  2.845071e-05  2.989744e-05
## ASV0195     -3.974510e-39 -2.879880e-05 -3.029422e-05
## ASV1213      1.288220e-37  7.722457e-04  8.080001e-04
## ASV1648     -1.108567e-37 -6.836676e-04 -7.157613e-04
## ASV6984     -1.032657e-37 -6.368995e-04 -6.666829e-04
## ASV0396     -1.600111e-38 -8.078363e-05 -8.454993e-05
## ASV4297      1.808061e-37  1.082104e-03  1.133443e-03
## ASV2622      2.354412e-37  1.418260e-03  1.485196e-03
## ASV3512      7.623514e-38  4.766368e-04  4.997039e-04
## ASV2411      1.381701e-37  8.540141e-04  8.944367e-04
## ASV2291     -6.825968e-38 -4.376772e-04 -4.594826e-04
## ASV0807      1.585891e-37  9.837712e-04  1.030504e-03
## ASV1292      5.570144e-38  3.344484e-04  3.498717e-04
## ASV1035      1.594171e-37  9.576366e-04  1.002512e-03
## ASV0070     -7.087068e-39 -3.729078e-05 -3.898988e-05
## ASV0255      1.574191e-38  9.247448e-05  9.672461e-05
## ASV0057     -5.990433e-38 -3.563231e-04 -3.730405e-04
## ASV0077     -1.112193e-38 -6.301965e-05 -6.594891e-05
## ASV0625      1.156712e-37  6.933558e-04  7.258437e-04
## ASV2464      7.722532e-37  4.632964e-03  4.849928e-03
## ASV1315      2.217288e-37  1.354858e-03  1.419356e-03
## ASV2673      1.851008e-37  1.149128e-03  1.203957e-03
## ASV2161      7.994847e-38  4.945589e-04  5.182244e-04
## ASV0337     -4.359738e-38 -2.669863e-04 -2.797262e-04
## ASV7680     -2.690768e-37 -1.659102e-03 -1.737173e-03
## ASV0611      1.410551e-37  8.688300e-04  9.101311e-04
## ASV3118     -1.649758e-37 -1.026159e-03 -1.074531e-03
## ASV1284      1.060834e-37  6.619875e-04  6.921362e-04
## ASV0889      1.060661e-37  6.389689e-04  6.693131e-04
## ASV4649     -5.757771e-38 -3.533187e-04 -3.698486e-04
## ASV1108     -1.261088e-37 -7.891387e-04 -8.265248e-04
## ASV0738      2.261826e-38  1.645518e-04  1.725559e-04
## ASV0473     -1.065807e-38 -7.092254e-05 -7.455896e-05
## ASV0598     -8.015355e-38 -4.793041e-04 -5.021372e-04
## ASV0429      1.126749e-37  6.814821e-04  7.136322e-04
## ASV1549      1.400120e-37  8.715199e-04  9.130075e-04
## ASV1203      1.233861e-37  7.464643e-04  7.814888e-04
## ASV4532      3.210107e-39  1.372302e-05  1.440565e-05
## ASV0274     -2.161423e-38 -1.210016e-04 -1.266848e-04
## ASV0163     -1.053436e-37 -6.301363e-04 -6.595647e-04
## ASV1298      4.374301e-38  2.599296e-04  2.718149e-04
## ASV9424     -2.313698e-37 -1.429064e-03 -1.496406e-03
## ASV0412      2.058934e-37  1.246689e-03  1.305488e-03
## ASV0284      5.384175e-38  3.169372e-04  3.316365e-04
## ASV0620     -5.010541e-38 -3.220995e-04 -3.373486e-04
## ASV0153     -1.587864e-37 -9.856560e-04 -1.032848e-03
## ASV0498      5.976205e-38  3.758388e-04  3.936122e-04
## ASV0097      4.121802e-38  2.553882e-04  2.675041e-04
## ASV0104     -2.823673e-37 -1.716999e-03 -1.798462e-03
## ASV1282      7.314477e-38  4.501119e-04  4.714658e-04
## ASV3883     -7.998682e-38 -5.016141e-04 -5.253733e-04
## ASV0801      5.102516e-38  3.206509e-04  3.355718e-04
## ASV1611     -1.887315e-37 -1.166342e-03 -1.221449e-03
## ASV0227     -3.826857e-38 -2.431090e-04 -2.548767e-04
## ASV0833      5.459195e-38  3.364231e-04  3.523836e-04
## ASV0718      2.694436e-37  1.652089e-03  1.730193e-03
## ASV1139      4.121910e-38  2.375966e-04  2.483900e-04
## ASV0766     -4.481193e-38 -2.808931e-04 -2.941222e-04
## ASV2091      2.927985e-37  1.747840e-03  1.830097e-03
## ASV1238     -1.097994e-37 -6.321833e-04 -6.616482e-04
## ASV9193     -2.467671e-38 -1.958827e-04 -2.049129e-04
## ASV0290      7.113213e-39  3.661694e-05  3.830783e-05
## ASV0231      8.988991e-38  5.450948e-04  5.706928e-04
## ASV0185      2.877618e-38  1.931398e-04  2.024846e-04
## ASV2330      8.622386e-38  5.126747e-04  5.367629e-04
## ASV3119     -4.174620e-38 -2.700638e-04 -2.830020e-04
## ASV2368     -1.160028e-37 -7.229232e-04 -7.570413e-04
## ASV0122     -4.085792e-38 -2.449189e-04 -2.565776e-04
## ASV1044      1.240979e-37  7.748314e-04  8.117206e-04
## ASV0160     -7.023484e-38 -4.156715e-04 -4.351160e-04
## ASV0326      1.906459e-38  1.162767e-04  1.218641e-04
## ASV1388      3.361188e-37  2.042972e-03  2.139630e-03
## ASV0792      2.062546e-37  1.245583e-03  1.303961e-03
## ASV0036     -5.161936e-38 -3.197732e-04 -3.350740e-04
## ASV2125      1.866811e-37  1.132937e-03  1.186534e-03
## ASV1075      8.440824e-39  5.254519e-05  5.515214e-05
## ASV0390      9.476759e-38  5.950666e-04  6.232740e-04
## ASV3790     -1.506360e-37 -9.226496e-04 -9.661469e-04
## ASV1535     -2.297414e-38 -1.575264e-04 -1.650600e-04
## ASV0263      1.375848e-37  8.399352e-04  8.793609e-04
## ASV0675      2.581611e-37  1.598271e-03  1.674006e-03
## ASV3348      2.636365e-38  1.664014e-04  1.745167e-04
## ASV0058     -9.080383e-38 -5.466377e-04 -5.724450e-04
## ASV4142      1.085380e-37  6.552869e-04  6.859309e-04
## ASV0059     -7.555678e-38 -4.533993e-04 -4.747556e-04
## ASV0013     -1.012731e-37 -6.173734e-04 -6.465967e-04
## ASV0033     -4.906090e-38 -3.042730e-04 -3.187863e-04
## ASV4354     -6.721233e-38 -4.117571e-04 -4.311635e-04
## ASV0022     -3.867359e-38 -2.402023e-04 -2.516322e-04
## ASV0134     -4.132029e-38 -2.587064e-04 -2.710611e-04
## ASV0415      9.518276e-40  1.768292e-05  1.860486e-05
## ASV10103    -2.344283e-37 -1.448356e-03 -1.516491e-03
## ASV1613      1.881773e-37  1.133817e-03  1.187062e-03
## ASV0135     -3.181329e-38 -1.878567e-04 -1.965798e-04
## ASV0469     -2.371467e-37 -1.431357e-03 -1.498391e-03
## ASV0471      1.669730e-37  1.030988e-03  1.079610e-03
## ASV0451     -2.199776e-38 -1.452445e-04 -1.524137e-04
## ASV0747      5.757427e-38  3.589770e-04  3.760051e-04
## ASV1314     -7.145632e-38 -4.473703e-04 -4.686158e-04
## ASV0425     -3.468560e-37 -2.068554e-03 -2.165574e-03
## ASV0559     -9.661613e-38 -5.818120e-04 -6.092101e-04
## ASV0148     -5.648886e-38 -3.323415e-04 -3.478918e-04
## ASV0129     -2.156876e-38 -1.126036e-04 -1.176951e-04
## ASV1072      4.025820e-38  2.349337e-04  2.459091e-04
## ASV2390      1.320843e-37  7.862453e-04  8.231079e-04
## ASV0548      1.115593e-37  6.801092e-04  7.123186e-04
## ASV0168     -7.664324e-38 -4.617167e-04 -4.834285e-04
## ASV0066     -6.179368e-38 -3.764217e-04 -3.942126e-04
## ASV0468     -3.954795e-38 -2.424289e-04 -2.538221e-04
## ASV0172     -2.112259e-38 -1.204400e-04 -1.259960e-04
## ASV0236     -4.232393e-38 -2.314898e-04 -2.419536e-04
## ASV0250      3.354387e-38  2.314324e-04  2.427734e-04
## ASV0338      3.517291e-38  2.284010e-04  2.393896e-04
## ASV0450     -2.462393e-39 -1.814394e-05 -1.907166e-05
## ASV0377      8.540282e-38  5.206318e-04  5.451617e-04
## ASV1022      1.087405e-38  6.700126e-05  7.010695e-05
## ASV6174     -9.225827e-39 -5.937362e-05 -6.221835e-05
## ASV0786      9.516520e-39  5.165487e-05  5.395435e-05
## ASV0053     -7.792030e-38 -4.784080e-04 -5.010368e-04
## ASV0697     -6.465317e-38 -3.883015e-04 -4.064848e-04
## ASV0785      1.187710e-37  7.181085e-04  7.519560e-04
## ASV1967     -1.094681e-37 -6.605854e-04 -6.917785e-04
## ASV0385      1.211612e-38  8.432608e-05  8.844300e-05
## ASV0295      2.560088e-39  2.213490e-05  2.330667e-05
## ASV0072     -7.811027e-38 -4.676915e-04 -4.896198e-04
## ASV0157     -3.021509e-38 -1.756062e-04 -1.837299e-04
## ASV0501      1.868061e-37  1.168316e-03  1.223802e-03
## ASV10729    -2.253751e-37 -1.389910e-03 -1.455499e-03
## ASV1470      1.482080e-37  8.505183e-04  8.903695e-04
## ASV0050     -1.794000e-37 -1.087571e-03 -1.138772e-03
## ASV0411     -3.253026e-38 -1.971051e-04 -2.063860e-04
## ASV0549      5.575762e-38  3.440235e-04  3.603932e-04
## ASV0184      1.778751e-38  1.081236e-04  1.131730e-04
## ASV0705      4.531555e-38  2.785023e-04  2.916326e-04
## ASV1715      1.031142e-37  6.305249e-04  6.602539e-04
## ASV0603      1.577904e-38  9.837949e-05  1.030120e-04
## ASV0826      1.428508e-37  8.629461e-04  9.036000e-04
## ASV0034     -5.786920e-38 -3.487990e-04 -3.651179e-04
## ASV0838      8.078048e-38  4.849613e-04  5.072320e-04
## ASV0614     -6.495840e-38 -3.960924e-04 -4.147806e-04
## ASV0014     -1.022465e-37 -6.219333e-04 -6.511924e-04
## ASV0585     -8.322572e-39 -5.167446e-05 -5.434074e-05
## ASV0016     -1.072154e-37 -6.523263e-04 -6.829687e-04
## ASV5394     -1.028938e-37 -6.313187e-04 -6.611418e-04
## ASV0666      1.988511e-37  1.196628e-03  1.252489e-03
## ASV2085      5.210316e-38  2.873010e-04  3.000506e-04
## ASV0003     -7.449963e-38 -4.529316e-04 -4.741635e-04
## ASV0346      1.589392e-38  1.063785e-04  1.116411e-04
## ASV0267     -1.158362e-38 -6.419578e-05 -6.680122e-05
## ASV0353      5.635721e-38  3.588322e-04  3.759273e-04
## ASV2419      2.054386e-37  1.242573e-03  1.300768e-03
## ASV0447      8.167316e-38  5.086960e-04  5.329457e-04
## ASV0654      1.379564e-37  8.446563e-04  8.845217e-04
## ASV0151      9.844258e-39  6.603616e-05  6.944791e-05
## ASV0065     -5.772039e-38 -3.466400e-04 -3.629010e-04
## ASV0527      1.502091e-37  9.154607e-04  9.584388e-04
## ASV4055     -3.264825e-38 -2.072086e-04 -2.171002e-04
## ASV0166     -8.182560e-38 -4.782385e-04 -5.004569e-04
## ASV0417     -5.932209e-38 -3.538695e-04 -3.703369e-04
## ASV0078     -4.234571e-38 -2.519293e-04 -2.636742e-04
## ASV0322     -5.471037e-38 -3.094260e-04 -3.237216e-04
## ASV0156     -9.647230e-38 -5.790517e-04 -6.062661e-04
## ASV0648     -2.834217e-37 -1.748618e-03 -1.831199e-03
## ASV0407     -7.646890e-39 -4.937796e-05 -5.168368e-05
## ASV2030     -3.953299e-38 -2.384990e-04 -2.498741e-04
## ASV0300      2.277743e-38  1.459910e-04  1.530074e-04
## ASV1150     -2.682781e-39 -1.466506e-05 -1.528155e-05
## ASV0958      7.004943e-38  4.378645e-04  4.587761e-04
## ASV0216     -8.478974e-38 -5.119527e-04 -5.357801e-04
## ASV0446      1.201951e-37  7.470616e-04  7.824487e-04
## ASV0367     -9.191606e-38 -5.645619e-04 -5.912098e-04
## ASV0200     -5.247794e-38 -3.185394e-04 -3.335727e-04
## ASV0334     -3.506741e-38 -2.019232e-04 -2.110054e-04
## ASV1311      3.554008e-38  2.130824e-04  2.228259e-04
## ASV0458      7.729885e-38  4.605129e-04  4.820742e-04
## ASV1371      7.512118e-39  4.717749e-05  4.944534e-05
## ASV0418      1.893337e-37  1.120701e-03  1.173104e-03
## ASV0004      1.804419e-38  1.080705e-04  1.131324e-04
## ASV1943      6.429812e-37  3.826408e-03  4.008246e-03
## ASV1495     -2.211632e-38 -1.535696e-04 -1.612495e-04
## ASV0901     -1.131054e-37 -6.983704e-04 -7.315018e-04
## ASV0628      5.546521e-38  3.311734e-04  3.464817e-04
## ASV0400      2.805425e-38  1.712796e-04  1.792761e-04
## ASV0116     -3.205427e-38 -1.969600e-04 -2.063028e-04
## ASV0788      2.271701e-37  1.397929e-03  1.464086e-03
## ASV0117      1.927075e-38  1.210921e-04  1.269105e-04
## ASV3137     -8.767456e-40 -4.648771e-06 -4.844600e-06
## ASV0001      2.197299e-38  1.307714e-04  1.368337e-04
## ASV1651      5.685277e-38  3.369699e-04  3.526195e-04
## ASV1692      1.886592e-37  1.164581e-03  1.219828e-03
## ASV0660      6.721280e-38  3.967397e-04  4.149136e-04
## ASV0508     -4.434416e-40 -5.463456e-06 -5.752443e-06
## ASV1660     -5.284335e-38 -3.327497e-04 -3.487223e-04
## ASV0233      4.099784e-38  2.497985e-04  2.616006e-04
## ASV1343     -1.274381e-37 -7.862168e-04 -8.233970e-04
## ASV0209      6.140143e-38  3.679730e-04  3.849784e-04
## ASV0193     -8.704938e-38 -5.049013e-04 -5.282168e-04
## ASV0357      1.377412e-38  8.869041e-05  9.314505e-05
## ASV0198      4.709804e-38  2.904221e-04  3.040629e-04
## ASV0007      2.311821e-38  1.371622e-04  1.435005e-04
## ASV1772     -3.325135e-38 -1.990915e-04 -2.083638e-04
## ASV0009      2.170475e-38  1.284295e-04  1.343440e-04
## ASV0006     -1.820060e-39 -1.376054e-05 -1.450942e-05
## ASV0011     -4.025319e-38 -2.479354e-04 -2.596401e-04
## ASV0015      1.405308e-38  8.346896e-05  8.735742e-05
## ASV0017      1.527496e-38  9.069456e-05  9.490464e-05
## ASV0235     -4.894084e-38 -3.060705e-04 -3.205438e-04
## ASV0382      1.920122e-38  1.247139e-04  1.307762e-04
## ASV2357      1.617275e-37  9.950562e-04  1.041932e-03
## ASV0567     -4.374086e-38 -2.654597e-04 -2.779285e-04
## ASV0165      2.807167e-38  1.738140e-04  1.820104e-04
## ASV0005      3.542869e-38  2.141538e-04  2.241721e-04
## ASV0384     -3.520415e-39 -1.619466e-05 -1.681119e-05
## ASV0002      6.019539e-39  3.656601e-05  3.830091e-05
## ASV3017      2.296311e-37  1.382574e-03  1.446859e-03
## ASV0091     -1.735548e-40 -6.336404e-07 -6.599795e-07
## ASV0186     -9.091321e-38 -5.564020e-04 -5.826031e-04
## ASV0370      2.619667e-38  1.626633e-04  1.701695e-04
## ASV0018      4.825078e-38  2.920391e-04  3.056994e-04
## ASV1377      7.336761e-37  4.435357e-03  4.642486e-03
## ASV0019      5.050491e-38  3.058255e-04  3.201086e-04
## ASV0023     -1.398700e-38 -8.854112e-05 -9.285579e-05
## ASV2194      5.683899e-38  3.433626e-04  3.596663e-04
## ASV1155      1.068389e-37  6.548323e-04  6.869331e-04
## ASV0510     -9.113869e-38 -5.206763e-04 -5.437484e-04
## ASV2371     -1.257836e-37 -7.503614e-04 -7.857251e-04
## ASV0024     -1.915673e-38 -1.202644e-04 -1.260652e-04
## ASV2452      1.456958e-37  8.677003e-04  9.076436e-04
## ASV2332     -1.617521e-37 -9.890974e-04 -1.035578e-03
## ASV2591      9.996402e-38  6.448841e-04  6.753297e-04
## ASV0521      7.497434e-38  4.638249e-04  4.857650e-04
## ASV5542      6.541575e-38  4.056084e-04  4.243714e-04
## ASV0336     -2.681139e-38 -1.544965e-04 -1.617954e-04
## ASV10102     1.374001e-37  8.510964e-04  8.911619e-04
## ASV16823    -2.104537e-37 -1.253189e-03 -1.312226e-03
## ASV3104      1.161414e-36  6.915872e-03  7.241139e-03
## ASV0781      1.274481e-37  7.827830e-04  8.192735e-04
## ASV10899     7.388709e-38  4.765424e-04  4.994311e-04
## ASV11222    -3.676031e-37 -2.188967e-03 -2.291812e-03
## ASV11327    -3.306391e-37 -1.968857e-03 -2.061209e-03
## ASV12458    -3.676031e-37 -2.188966e-03 -2.291474e-03
## ASV1636      2.704271e-38  1.703174e-04  1.781024e-04
## ASV1890     -2.399684e-37 -1.421978e-03 -1.488489e-03
## ASV2898      2.747572e-37  1.662717e-03  1.740116e-03
## ASV8328     -7.930990e-40  3.779756e-05  4.046857e-05
## ASV0709     -3.031337e-37 -1.841324e-03 -1.926845e-03
## ASV0856      2.031112e-37  1.264499e-03  1.324413e-03
## ASV0909     -2.700791e-38 -1.245277e-04 -1.287953e-04
## ASV0937     -1.737019e-37 -1.064047e-03 -1.114541e-03
## ASV11390    -5.207269e-37 -3.100773e-03 -3.245646e-03
## ASV11966     1.134161e-37  7.148652e-04  7.488885e-04
## ASV12990     7.930626e-38  4.868453e-04  5.090178e-04
## ASV14797     1.386496e-37  8.363583e-04  8.748448e-04
## ASV14904    -7.391907e-37 -4.401659e-03 -4.607207e-03
## ASV15304     5.730069e-38  3.727405e-04  3.906452e-04
## ASV16696    -2.614804e-37 -1.557037e-03 -1.629650e-03
## ASV1690      4.124258e-37  2.567047e-03  2.689161e-03
## ASV2029      3.095950e-37  1.876496e-03  1.964054e-03
## ASV2834      4.893075e-37  2.999998e-03  3.141355e-03
## ASV4003      2.818388e-37  1.773739e-03  1.858366e-03
## ASV4064      1.855609e-37  1.131598e-03  1.184883e-03
## ASV4294      9.559295e-38  6.170254e-04  6.467226e-04
## ASV4609      5.935566e-38  3.537827e-04  3.691924e-04
## ASV6283     -2.446292e-37 -1.456693e-03 -1.524661e-03
## ASV6491     -3.488537e-37 -2.077319e-03 -2.174085e-03
## ASV7453      1.430583e-37  9.047425e-04  9.479659e-04
## ASV7959      3.215015e-38  2.230256e-04  2.340121e-04
## ASV8219      3.595766e-36  2.141170e-02  2.240804e-02
## ASV8547     -3.128805e-37 -1.863109e-03 -1.949662e-03
## ASV9319      1.267838e-37  7.867417e-04  8.237555e-04
## ASV9382     -6.035180e-37 -3.593768e-03 -3.760550e-03
## ASV11516    -4.070196e-37 -2.423678e-03 -2.535974e-03
## ASV14377    -2.954957e-37 -1.759587e-03 -1.840980e-03
## ASV1867      2.355221e-37  1.450559e-03  1.518951e-03
## ASV1895      4.075438e-38  2.494681e-04  2.609485e-04
## ASV3168      1.342523e-37  8.089223e-04  8.462066e-04
## ASV4449      8.479981e-37  5.157249e-03  5.399111e-03
## ASV6596      1.511414e-37  9.585873e-04  1.004690e-03
## ASV7492     -4.627085e-38 -2.521238e-04 -2.629425e-04
## ASV9854     -7.833338e-38 -4.611967e-04 -4.825205e-04
## ASV6296      6.632255e-36  3.949307e-02  4.131539e-02
## ASV4201      5.879822e-38  3.967408e-04  4.167298e-04
## ASV0552      1.527666e-37  9.423474e-04  9.868188e-04
## ASV3671     -8.300008e-38 -4.935301e-04 -5.163517e-04
## ASV3529     -4.642867e-38 -2.583725e-04 -2.695549e-04
## ASV1060      5.877354e-38  3.627275e-04  3.799639e-04
## ASV0239     -6.645116e-38 -3.928176e-04 -4.107908e-04
## ASV5711     -2.515455e-37 -1.517585e-03 -1.588186e-03
## ASV4152     -4.046551e-37 -2.458585e-03 -2.573714e-03
## ASV1461      1.917535e-37  1.146128e-03  1.198696e-03
## ASV2877      9.931301e-38  5.929329e-04  6.203455e-04
## ASV0012      1.314663e-38  8.053713e-05  8.435571e-05
## ASV9823      3.793949e-38  2.014065e-04  2.105292e-04
## ASV0008      1.414635e-38  8.633042e-05  9.040265e-05
## ASV7832     -2.512106e-37 -1.533585e-03 -1.605333e-03
## ASV1915     -7.525957e-39 -3.772769e-05 -3.916131e-05
## ASV0055      2.450120e-39  1.118357e-05  1.161443e-05
## ASV0032      2.728753e-38  1.642429e-04  1.717981e-04
## ASV2977     -3.561796e-37 -2.155099e-03 -2.255660e-03
## ASV0466      2.733792e-37  1.624689e-03  1.699408e-03
## ASV3866      1.760754e-37  1.084758e-03  1.135957e-03
## ASV0040      4.699517e-38  2.882762e-04  3.018783e-04
## ASV0496     -1.288536e-38 -9.531055e-05 -1.003390e-04
## ASV0052      6.057237e-38  3.693449e-04  3.866050e-04
## ASV3828     -3.751563e-37 -2.278264e-03 -2.384331e-03
## ASV1930      1.169582e-37  7.142018e-04  7.475659e-04
## ASV2126      1.456463e-37  8.835387e-04  9.247619e-04
## ASV0793      1.620282e-37  9.960381e-04  1.043321e-03
## ASV0299     -1.311933e-38 -8.004298e-05 -8.367978e-05
## ASV0208      1.147054e-37  7.102073e-04  7.437454e-04
## ASV0511     -6.989265e-38 -4.165831e-04 -4.355324e-04
## ASV1123     -2.239972e-37 -1.327560e-03 -1.388324e-03
## ASV0099     -7.844886e-39 -4.310869e-05 -4.505846e-05
## ASV0752     -6.224289e-38 -3.927402e-04 -4.114939e-04
## ASV0883      8.109358e-38  5.028546e-04  5.268019e-04
## ASV0683      1.690633e-37  1.048815e-03  1.098616e-03
## ASV4117     -4.299106e-37 -2.609087e-03 -2.730973e-03
## ASV2172      3.570402e-38  2.129440e-04  2.227801e-04
## ASV0330     -4.963671e-38 -3.021133e-04 -3.163456e-04
## ASV0728      2.603246e-37  1.590600e-03  1.665409e-03
## ASV0499      6.170363e-38  3.826900e-04  4.008564e-04
## ASV0120     -1.087437e-37 -6.633760e-04 -6.944264e-04
## ASV1446      1.140615e-37  6.670806e-04  6.973672e-04
## ASV17171    -1.941736e-37 -1.183941e-03 -1.239357e-03
## ASV0533      1.709255e-38  1.077949e-04  1.129730e-04
## ASV2495     -6.593953e-38 -4.180520e-04 -4.381783e-04
## ASV5582      9.415903e-38  5.429951e-04  5.673676e-04
## ASV1488      6.620589e-38  4.358554e-04  4.564507e-04
## ASV0682      4.548255e-38  2.842487e-04  2.977569e-04
## ASV0068     -5.092313e-38 -3.125196e-04 -3.272996e-04
## ASV1987     -1.849195e-37 -1.155610e-03 -1.210727e-03
## ASV0035     -5.588354e-39 -4.207597e-05 -4.441119e-05
## ASV7192     -1.485948e-37 -8.925035e-04 -9.338268e-04
## ASV0873      9.174617e-38  4.349824e-04  4.498018e-04
## ASV4749      7.302796e-39  1.710469e-05  1.663252e-05
## ASV2174      1.504672e-37  8.698641e-04  9.097474e-04
## ASV1476     -8.843946e-38 -5.434809e-04 -5.692144e-04
## ASV0740     -3.028369e-37 -1.870471e-03 -1.959218e-03
## ASV0170     -3.959415e-38 -2.427122e-04 -2.541011e-04
## ASV2466     -2.982967e-37 -1.822318e-03 -1.907737e-03
## ASV1709      1.284559e-37  7.692421e-04  8.046575e-04
## ASV6170     -7.223576e-37 -4.327063e-03 -4.531277e-03
## ASV3673      2.191351e-37  1.300403e-03  1.361937e-03
## ASV1745      4.254043e-38  2.194787e-04  2.296968e-04
## ASV0380     -1.985728e-37 -1.089039e-03 -1.139624e-03
## ASV0426      4.129004e-39  4.788244e-05  5.000192e-05
## ASV0202     -2.116519e-39 -4.753710e-07  1.808413e-08
## ASV6350     -2.479734e-37 -1.445049e-03 -1.513208e-03
## ASV0713     -9.664623e-38 -5.935452e-04 -6.215544e-04
## ASV1822      4.759007e-39  4.271597e-05  4.452426e-05
## ASV4569      3.078668e-37  1.834215e-03  1.919831e-03
## ASV0030     -2.585480e-38 -1.607125e-04 -1.683411e-04
## ASV0331      1.021185e-37  6.363262e-04  6.664857e-04
## ASV2981      2.951722e-37  1.826421e-03  1.912295e-03
## ASV0828     -2.090453e-38 -2.355712e-04 -2.475516e-04
## ASV2440      2.583330e-37  1.593948e-03  1.669136e-03
## ASV3006     -1.603036e-36 -8.956017e-03 -9.376792e-03
## ASV3875      1.490529e-35  8.327445e-02  8.718054e-02
## ASV4511      1.445779e-37  8.954557e-04  9.380166e-04
## ASV4700     -5.895173e-37 -3.293577e-03 -3.447812e-03
## ASV5804     -1.384475e-35 -7.734926e-02 -8.096561e-02
## ASV6826      2.060156e-37  1.283910e-03  1.344766e-03
## ASV7280      1.873374e-37  1.188132e-03  1.244097e-03
## ASV7535     -5.895173e-37 -3.293573e-03 -3.447403e-03
## ASV0651     -1.091351e-37 -6.533693e-04 -6.832769e-04
## ASV0913      2.359889e-37  1.461044e-03  1.530233e-03
## ASV10832    -6.290752e-37 -3.514578e-03 -3.678471e-03
## ASV1117     -5.679100e-37 -3.383887e-03 -3.542450e-03
## ASV11329     7.265263e-38  4.923408e-04  5.162496e-04
## ASV13209    -2.571526e-39  5.421244e-05  5.703754e-05
## ASV1345      1.210874e-37  7.732460e-04  8.100197e-04
## ASV1719     -8.859424e-37 -4.949663e-03 -5.179960e-03
## ASV1886      1.506468e-37  9.030522e-04  9.453374e-04
## ASV2158     -2.573313e-38 -7.835439e-05 -8.140827e-05
## ASV2189      2.488408e-37  1.512563e-03  1.583690e-03
## ASV2257      2.615986e-37  1.573375e-03  1.647930e-03
## ASV2283      6.863995e-37  3.834835e-03  4.012645e-03
## ASV2328      4.228965e-37  2.362673e-03  2.472046e-03
## ASV2434     -3.743014e-37 -2.197603e-03 -2.300617e-03
## ASV2648      7.720427e-37  4.313308e-03  4.512287e-03
## ASV2698      6.702958e-37  4.108988e-03  4.302850e-03
## ASV2775      2.212879e-37  1.303667e-03  1.363750e-03
## ASV3171      3.722075e-37  2.079476e-03  2.175090e-03
## ASV3227      3.432870e-37  2.013560e-03  2.105956e-03
## ASV3397      1.461054e-37  9.258490e-04  9.701596e-04
## ASV3444      4.947089e-37  2.886485e-03  3.020937e-03
## ASV3556      1.548396e-36  8.650683e-03  9.046894e-03
## ASV3606     -3.639624e-36 -2.033409e-02 -2.126390e-02
## ASV4190      4.338340e-37  2.643988e-03  2.768372e-03
## ASV4197      2.919344e-37  1.706539e-03  1.785819e-03
## ASV4722      4.236371e-37  2.549755e-03  2.668884e-03
## ASV4765      2.112503e-37  1.325927e-03  1.387284e-03
## ASV4809      9.151299e-37  5.112702e-03  5.345649e-03
## ASV4846      3.716586e-37  2.284232e-03  2.391018e-03
## ASV4903     -3.711158e-38 -1.451727e-04 -1.510288e-04
## ASV4944     -3.748268e-37 -2.094102e-03 -2.189365e-03
## ASV5151      1.359609e-37  4.499084e-04  4.640374e-04
## ASV5413     -8.246019e-37 -4.606926e-03 -4.816142e-03
## ASV5537     -8.859424e-37 -4.949623e-03 -5.174039e-03
## ASV5688      7.447089e-37  4.160571e-03  4.348906e-03
## ASV5752      1.825374e-37  1.157489e-03  1.212991e-03
## ASV6122     -9.540121e-37 -5.329911e-03 -5.570886e-03
## ASV6135      5.008681e-37  2.798267e-03  2.924577e-03
## ASV6188     -3.041284e-36 -1.699114e-02 -1.775686e-02
## ASV6216      6.352992e-37  3.746379e-03  3.919583e-03
## ASV6242      5.008681e-37  2.798263e-03  2.923996e-03
## ASV6383      3.131950e-36  1.749765e-02  1.828259e-02
## ASV6781      6.970657e-37  3.894381e-03  4.068800e-03
## ASV6799     -1.323819e-36 -7.395934e-03 -7.726643e-03
## ASV7374     -2.809296e-37 -1.569501e-03 -1.639568e-03
## ASV7539     -3.748268e-37 -2.094086e-03 -2.187420e-03
## ASV8591     -9.540121e-37 -5.329880e-03 -5.567053e-03
## ASV8637      4.188427e-36  2.339992e-02  2.443950e-02
## ASV12796    -5.527703e-37 -3.088216e-03 -3.225194e-03
## ASV1934      2.493290e-37  1.527348e-03  1.599124e-03
## ASV22549     1.066740e-38  1.178962e-04  1.249630e-04
## ASV29857    -2.144237e-37 -1.197941e-03 -1.250994e-03
## ASV3215      2.601109e-37  1.612452e-03  1.688994e-03
## ASV3236     -5.527703e-37 -3.088212e-03 -3.224738e-03
## ASV3954     -5.527703e-37 -3.088210e-03 -3.224515e-03
## ASV4850      3.705731e-37  2.070312e-03  2.161542e-03
## ASV5225      3.578683e-36  1.999331e-02  2.087291e-02
## ASV5532     -1.911598e-37 -1.067967e-03 -1.114876e-03
## ASV7258      1.104303e-37  7.693184e-04  8.085581e-04
## ASV9474     -7.248422e-38 -3.513025e-04 -3.648849e-04
## ASV11857    -7.182966e-37 -4.012957e-03 -4.188948e-03
## ASV1202     -4.561803e-37 -2.548572e-03 -2.660161e-03
## ASV14742     9.868216e-38  6.509266e-04  6.830413e-04
## ASV16652     7.877055e-38  5.079298e-04  5.329476e-04
## ASV2019      3.105732e-37  1.837442e-03  1.921643e-03
## ASV2410     -6.630715e-37 -4.024512e-03 -4.212394e-03
## ASV2718      1.573889e-37  9.839136e-04  1.030705e-03
## ASV2738      5.107838e-37  3.018564e-03  3.156476e-03
## ASV2876      3.317386e-37  1.853343e-03  1.934217e-03
## ASV3177      4.445615e-37  2.483656e-03  2.591859e-03
## ASV4367      5.493700e-37  3.069194e-03  3.202690e-03
## ASV4635      1.325629e-37  8.859676e-04  9.301300e-04
## ASV4896      8.582928e-38  6.260056e-04  6.590226e-04
## ASV4907      1.158831e-37  7.562613e-04  7.936051e-04
## ASV5230     -4.276572e-37 -2.389212e-03 -2.493168e-03
## ASV6509     -4.561803e-37 -2.548562e-03 -2.659272e-03
## ASV7376     -3.263923e-37 -1.823468e-03 -1.902552e-03
## ASV8163     -4.863810e-37 -2.717282e-03 -2.834940e-03
## ASV8195     -4.276572e-37 -2.389206e-03 -2.492491e-03
## ASV8923      1.072871e-37  6.968094e-04  7.310370e-04
## ASV9666     -2.509044e-37 -1.316698e-03 -1.369980e-03
## ASV1482      1.922554e-37  1.198570e-03  1.255712e-03
## ASV2726      1.758705e-37  1.100337e-03  1.152980e-03
## ASV3281     -1.781960e-36 -9.955316e-03 -1.038511e-02
## ASV4235     -1.781960e-36 -9.955310e-03 -1.038441e-02
## ASV4808      3.368542e-37  1.987811e-03  2.078021e-03
## ASV4861     -8.319372e-37 -4.880285e-03 -5.100198e-03
## ASV5276      4.807266e-37  2.837489e-03  2.965989e-03
## ASV5837      1.458067e-37  8.979081e-04  9.402433e-04
## ASV7098      2.111962e-37  1.294560e-03  1.355325e-03
## ASV8451     -3.033825e-37 -1.694911e-03 -1.767441e-03
## ASV8694     -1.781960e-36 -9.955289e-03 -1.038062e-02
## ASV0905     -6.407135e-38 -4.099201e-04 -4.298421e-04
## ASV2900      3.940290e-37  2.268400e-03  2.368293e-03
## ASV3963     -4.071805e-37 -2.319272e-03 -2.420180e-03
## ASV0041     -6.218917e-38 -3.869361e-04 -4.054036e-04
## ASV1865      1.779340e-37  1.129992e-03  1.184791e-03
## ASV1140      1.014314e-37  6.390151e-04  6.698800e-04
## ASV1179      1.094094e-37  6.710392e-04  7.026142e-04
## ASV0279      1.710284e-37  1.031533e-03  1.079367e-03
## ASV0043     -2.664300e-38 -1.726818e-04 -1.812040e-04
## ASV2097     -1.072570e-37 -6.275482e-04 -6.555301e-04
## ASV0309     -2.061420e-38 -1.227139e-04 -1.284753e-04
## ASV0607      2.591258e-37  1.594127e-03  1.668959e-03
## ASV0025     -7.143956e-38 -4.418604e-04 -4.627972e-04
## ASV2284     -3.103134e-37 -1.794986e-03 -1.878536e-03
## ASV0556      6.882204e-38  4.400105e-04  4.609413e-04
## ASV5040     -1.489317e-37 -1.324548e-03 -1.404545e-03
## ASV2924     -1.017458e-36 -5.817674e-03 -6.072351e-03
## ASV1331      2.332497e-37  1.421257e-03  1.487849e-03
## ASV0506     -1.122398e-37 -6.443734e-04 -6.739280e-04
## ASV1514      3.524163e-37  2.151919e-03  2.252799e-03
## ASV2144      3.377438e-37  2.055714e-03  2.151825e-03
## ASV2265      2.209608e-37  1.349445e-03  1.412847e-03
## ASV5156      1.976386e-37  1.100442e-03  1.150080e-03
## ASV5534      6.386076e-38  3.434711e-04  3.585794e-04
## ASV5747      1.966771e-52 -2.222768e-04 -2.369421e-04
## ASV6657      1.810529e-37  1.070558e-03  1.120301e-03
## ASV0658     -1.396279e-37 -8.083678e-04 -8.454074e-04
## ASV0716      2.382154e-37  1.423678e-03  1.489188e-03
## ASV1657      4.796871e-37  2.795528e-03  2.922851e-03
## ASV1885      4.282908e-37  2.414702e-03  2.522725e-03
## ASV2333      2.031212e-37  1.226169e-03  1.283183e-03
## ASV3375      1.663026e-37  9.733196e-04  1.017973e-03
## ASV4317      1.382353e-37  8.449170e-04  8.848749e-04
## ASV9599     -4.454021e-53 -9.293128e-05 -9.952581e-05
## ASV0175     -2.226034e-37 -1.337292e-03 -1.398813e-03
## ASV1032      9.934150e-38  5.775129e-04  6.037152e-04
## ASV1235      1.902673e-37  1.067085e-03  1.114083e-03
## ASV1262      2.263316e-37  1.369226e-03  1.432724e-03
## ASV1320      1.195597e-37  7.680913e-04  8.052841e-04
## ASV13797     1.340585e-37  7.991933e-04  8.361789e-04
## ASV1491      1.695400e-37  1.109538e-03  1.163787e-03
## ASV15014     7.449680e-53 -7.216620e-05 -7.741628e-05
## ASV1510      2.466246e-37  1.551977e-03  1.625857e-03
## ASV1551      8.703714e-37  5.329481e-03  5.579247e-03
## ASV1919      5.904668e-38  5.179888e-04  5.462545e-04
## ASV2114      1.710338e-37  1.003418e-03  1.049486e-03
## ASV21486     5.488312e-53 -6.202729e-05 -6.650018e-05
## ASV2448      1.724039e-37  1.028314e-03  1.075772e-03
## ASV2589      3.368275e-37  1.964065e-03  2.053844e-03
## ASV2608      2.164775e-37  1.298232e-03  1.358538e-03
## ASV2786      4.264204e-37  2.584720e-03  2.705603e-03
## ASV2827      1.541384e-37  9.212053e-04  9.638701e-04
## ASV2872      6.812204e-37  4.024799e-03  4.209535e-03
## ASV3125      1.340457e-37  7.880010e-04  8.239311e-04
## ASV3247      2.912571e-37  1.723231e-03  1.802035e-03
## ASV3451      1.692142e-52 -1.912416e-04 -2.060923e-04
## ASV3465      1.953441e-38  6.223441e-05  6.356612e-05
## ASV3809      3.951174e-37  2.326756e-03  2.432502e-03
## ASV4006      1.905472e-37  1.130198e-03  1.181825e-03
## ASV4046      2.808132e-37  1.661941e-03  1.737674e-03
## ASV4938      4.284200e-38  1.618752e-04  1.660738e-04
## ASV5435      4.537792e-52 -3.239063e-04 -3.498005e-04
## ASV5605      1.749850e-37  9.776030e-04  1.020602e-03
## ASV5635      1.115075e-52 -1.080203e-04 -1.166963e-04
## ASV5743      1.322655e-37  7.889538e-04  8.252882e-04
## ASV6627      1.486809e-52 -1.120244e-04 -1.211270e-04
## ASV6785     -1.025443e-51 -1.247289e-04 -1.348470e-04
## ASV7368      1.590047e-37  9.698073e-04  1.015158e-03
## ASV9118      6.479953e-38  3.614582e-04  3.772073e-04
## ASV9135      1.239138e-37  6.766330e-04  7.056516e-04
## ASV9435      1.419904e-37  8.074158e-04  8.430300e-04
## ASV9671      2.296261e-52 -1.597049e-04 -1.729646e-04
## ASV0387     -2.396949e-37 -1.401696e-03 -1.465105e-03
## ASV0454     -3.788763e-37 -2.241317e-03 -2.343685e-03
## ASV0751     -1.136153e-37 -6.497461e-04 -6.785148e-04
## ASV1081      2.209171e-37  1.344647e-03  1.407501e-03
## ASV1332      4.005702e-37  2.404173e-03  2.515074e-03
## ASV2659      4.328537e-37  2.645658e-03  2.769190e-03
## ASV2979      2.026173e-37  1.192464e-03  1.246374e-03
## ASV4184      3.034014e-37  1.728930e-03  1.804911e-03
## ASV6198      9.400632e-38  5.497335e-04  5.745776e-04
## ASV7454      9.997174e-38  5.866959e-04  6.132029e-04
## ASV8198      9.608593e-38  5.177724e-04  5.392087e-04
## ASV0855      2.377581e-37  1.446368e-03  1.513758e-03
## ASV10092     1.137084e-37  6.681748e-04  6.984176e-04
## ASV1532      2.065198e-37  1.281133e-03  1.341815e-03
## ASV2553      3.782792e-37  2.303939e-03  2.411423e-03
## ASV2741      5.020895e-37  3.129358e-03  3.278619e-03
## ASV4095      2.887305e-37  1.853595e-03  1.944322e-03
## ASV5295      1.190888e-37  6.828938e-04  7.129995e-04
## ASV5787      7.477636e-53 -6.542858e-05 -7.115449e-05
## ASV9455      1.517897e-37  9.007025e-04  9.416044e-04
## ASV10879     1.366029e-37  8.196713e-04  8.573776e-04
## ASV3997      1.644371e-37  1.042208e-03  1.092377e-03
## ASV6760      6.602837e-38  3.276237e-04  3.398078e-04
## ASV6990      1.453009e-37  8.510259e-04  8.892470e-04
## ASV9560      9.579176e-38  5.474192e-04  5.713474e-04
## ASV0220     -2.090928e-38 -1.263662e-04 -1.321837e-04
## ASV2518      8.604487e-38  5.247943e-04  5.493035e-04
## ASV3615      2.213546e-37  1.331536e-03  1.392803e-03
## ASV0075     -3.347411e-40 -3.743834e-06 -4.017609e-06
## ASV8070      1.669427e-38  7.344531e-05  7.562886e-05
## ASV1658      9.079091e-38  5.336328e-04  5.577248e-04
## ASV0773      1.647593e-37  9.786861e-04  1.023272e-03
## ASV0799      2.020012e-38  1.131643e-04  1.177596e-04
## ASV1839     -1.122440e-37 -6.740121e-04 -7.052346e-04
## ASV0265      1.240564e-37  7.752919e-04  8.123111e-04
## ASV3741      4.937605e-38  2.876083e-04  3.005813e-04
## ASV0847      1.760188e-37  1.074585e-03  1.124981e-03
## ASV1026      2.340234e-37  1.415798e-03  1.481386e-03
## ASV1222     -7.229859e-38 -3.947568e-04 -4.110620e-04
## ASV0729     -3.645871e-39 -2.259586e-05 -2.365053e-05
## ASV0143     -6.090511e-38 -3.603213e-04 -3.766392e-04
## ASV1328      2.505670e-38  1.678796e-04  1.767561e-04
## ASV9078     -5.193869e-38 -3.714664e-04 -3.912325e-04
## ASV0027     -6.747669e-38 -4.168501e-04 -4.365371e-04
## ASV0546     -8.435156e-38 -4.937667e-04 -5.159390e-04
## ASV1136      1.939997e-37  1.176770e-03  1.231369e-03
## ASV3081      1.013115e-37  6.167467e-04  6.454976e-04
## ASV0531      2.614338e-38  1.770262e-04  1.861597e-04
## ASV2525      1.557502e-37  9.270206e-04  9.690000e-04
## ASV1083     -3.479550e-38 -1.914853e-04 -1.994878e-04
## ASV0424     -2.109046e-38 -1.304192e-04 -1.365701e-04
## ASV0644      1.703669e-53  4.590892e-05  4.997082e-05
## ASV6007      3.475206e-54 -4.563293e-05 -4.983262e-05
## ASV0564      6.878421e-38  4.311551e-04  4.518177e-04
## ASV1938      2.419944e-37  1.396209e-03  1.457942e-03
## ASV6516     -3.483260e-37 -2.131790e-03 -2.231590e-03
## ASV0503     -1.495687e-37 -8.682040e-04 -9.066508e-04
## ASV6913     -7.124961e-37 -4.277927e-03 -4.474243e-03
## ASV0164     -8.536975e-38 -5.265638e-04 -5.513605e-04
## ASV1576      2.494705e-37  1.507118e-03  1.576716e-03
## ASV1725      1.148624e-37  7.312357e-04  7.666420e-04
## ASV4501      7.395110e-38  4.129562e-04  4.303536e-04
## ASV10678    -3.222201e-37 -1.966901e-03 -2.058746e-03
## ASV0944      4.904575e-38  3.079517e-04  3.226522e-04
## ASV2292      2.670896e-37  1.603679e-03  1.677355e-03
## ASV1090      1.068937e-37  6.445111e-04  6.740677e-04
## ASV9117     -8.353717e-38 -4.619769e-04 -4.813255e-04
## ASV0285     -1.088630e-37 -7.429450e-04 -7.812212e-04
## ASV0463     -7.886743e-38 -4.601199e-04 -4.805244e-04
## ASV3199      1.014302e-37  5.861064e-04  6.118684e-04
## ASV0150     -1.234046e-38 -8.691275e-05 -9.152946e-05
## ASV6583     -8.712672e-38 -4.942111e-04 -5.153813e-04
## ASV0392      8.854375e-39  4.982015e-05  5.188429e-05
## ASV14007    -1.199656e-37 -7.201223e-04 -7.532461e-04
## ASV0177     -5.704741e-38 -3.398868e-04 -3.553331e-04
## ASV6448     -7.463725e-38 -5.039529e-04 -5.297938e-04
## ASV5399     -4.904931e-37 -3.137390e-03 -3.290703e-03
## ASV0277     -1.271209e-38 -7.539408e-05 -7.888630e-05
## ASV2599      1.022425e-37  4.623241e-04  4.764225e-04
## ASV13465    -4.767511e-38 -2.481861e-04 -2.580400e-04
## ASV2412      3.036561e-38  1.859108e-04  1.945917e-04
## ASV0423     -1.381358e-38 -7.197817e-05 -7.475438e-05
## ASV5187      1.820675e-37  1.004680e-03  1.046937e-03
## ASV0701     -1.027818e-37 -6.326594e-04 -6.623949e-04
## ASV4248      5.177993e-38  3.373760e-04  3.541209e-04
## ASV0519      9.542346e-38  5.951141e-04  6.233755e-04
## ASV0764      2.479811e-38  1.567015e-04  1.642343e-04
## ASV5385     -8.604804e-38 -5.323826e-04 -5.575389e-04
## ASV3021     -1.674323e-37 -9.411325e-04 -9.817319e-04
## ASV4119     -3.931069e-37 -2.373408e-03 -2.483381e-03
## ASV2534     -9.613745e-39 -8.829237e-05 -9.400102e-05
## ASV1061      8.995275e-38  5.847969e-04  6.136957e-04
## ASV0670     -2.615177e-38 -1.602765e-04 -1.677943e-04
## ASV1384      1.053829e-37  6.823969e-04  7.161078e-04
## ASV1981      2.695282e-37  1.674498e-03  1.754020e-03
## ASV9632     -7.204524e-38 -3.707737e-04 -3.851772e-04
## ASV4564      8.070990e-38  4.950051e-04  5.182425e-04
## ASV5289     -4.759924e-38 -3.049108e-04 -3.197692e-04
## ASV0516      1.920113e-37  1.173491e-03  1.228336e-03
## ASV1463     -2.704559e-37 -1.647475e-03 -1.724482e-03
## ASV0969      1.136971e-38  6.514650e-05  6.799448e-05
## ASV1113     -6.127243e-38 -3.753544e-04 -3.928743e-04
## ASV1234     -6.429455e-38 -4.354083e-04 -4.576837e-04
## ASV3814     -2.367292e-38 -2.385109e-04 -2.537641e-04
## ASV1000      1.258896e-37  7.564702e-04  7.911967e-04
## ASV0079     -1.123528e-38 -7.770468e-05 -8.175814e-05
## ASV0145      2.731065e-38  1.459758e-04  1.518183e-04
## ASV0457     -1.629311e-37 -9.829615e-04 -1.028318e-03
## ASV1485      1.206492e-38  7.671716e-05  8.046764e-05
## ASV0535      4.309534e-38  2.879542e-04  3.026085e-04
## ASV0259     -8.986826e-38 -5.468314e-04 -5.722851e-04
## ASV0570      2.513888e-38  1.635119e-04  1.715698e-04
## ASV0906      1.057052e-37  6.320656e-04  6.609445e-04
## ASV1748      1.249950e-37  6.514733e-04  6.766053e-04
## ASV5520     -1.194000e-37 -7.981965e-04 -8.387080e-04
## ASV2288     -3.377115e-37 -2.062680e-03 -2.159163e-03
## ASV1887     -5.367427e-38 -3.969655e-04 -4.185593e-04
## ASV0374     -1.648548e-38 -9.051340e-05 -9.436284e-05
## ASV0823      2.060452e-37  1.220586e-03  1.275778e-03
## ASV0717      1.453928e-38  8.957513e-05  9.385033e-05
## ASV0431     -3.898732e-38 -2.425993e-04 -2.541962e-04
## ASV1030      4.475689e-37  2.786036e-03  2.918432e-03
## ASV1082     -5.908727e-38 -3.644127e-04 -3.815531e-04
## ASV2684      1.676351e-39  4.461175e-05  4.814162e-05
## ASV0051      5.656565e-38  3.476904e-04  3.641112e-04
## ASV0513     -1.894772e-38 -1.115132e-04 -1.165060e-04
## ASV0581      1.034704e-37  6.352042e-04  6.649895e-04
## ASV7282      2.685435e-38  1.932807e-04  2.036251e-04
## ASV3009     -8.880667e-38 -5.439061e-04 -5.693869e-04
## ASV2106      8.997726e-38  6.182338e-04  6.501646e-04
## ASV1012      7.290822e-38  4.559464e-04  4.777124e-04
## ASV0921      7.272467e-38  4.582077e-04  4.803122e-04
## ASV0010     -4.390167e-38 -2.712342e-04 -2.840256e-04
## ASV1178      1.914777e-38  1.218787e-04  1.278449e-04
## ASV2848     -1.225613e-37 -7.347067e-04 -7.684428e-04
## ASV0586      2.891570e-37  1.799485e-03  1.884853e-03
## ASV4225     -5.387505e-37 -2.865637e-03 -2.979917e-03
## ASV2156     -1.638901e-37 -1.013782e-03 -1.061727e-03
## ASV9778     -1.189170e-37 -7.306053e-04 -7.648781e-04
## ASV0493     -2.498071e-37 -1.504509e-03 -1.573805e-03
## ASV3770     -1.804909e-38 -1.613995e-04 -1.713639e-04
## ASV0470      1.698084e-37  1.042647e-03  1.091506e-03
## ASV0262     -6.558256e-38 -4.330104e-04 -4.546901e-04
## ASV0998      4.369060e-38  2.708378e-04  2.836595e-04
## ASV7708     -2.314678e-38 -1.347747e-04 -1.407608e-04
## ASV0453     -1.781388e-38 -1.076625e-04 -1.126374e-04
## ASV0044      7.166090e-38  4.374938e-04  4.578704e-04
## ASV5490      4.363897e-38  2.553332e-04  2.668306e-04
## ASV2638     -2.696673e-38 -1.503244e-04 -1.571540e-04
## ASV0829      2.460662e-37  1.508495e-03  1.578927e-03
## ASV0601      7.938435e-38  4.973548e-04  5.209710e-04
## ASV0234      5.615179e-39  3.708217e-05  3.892790e-05
## ASV0133      1.242973e-37  7.637415e-04  7.996636e-04
## ASV0323      3.930224e-38  2.478316e-04  2.597864e-04
## ASV0854     -2.865597e-38 -1.744254e-04 -1.825060e-04
## ASV0110      7.796997e-38  4.805620e-04  5.032855e-04
## ASV0816     -7.550863e-39 -4.728292e-05 -4.956166e-05
## ASV1031     -3.135701e-38 -1.830123e-04 -1.911265e-04
## ASV0144     -3.535332e-38 -2.204663e-04 -2.310490e-04
## ASV0020     -1.581791e-38 -1.014300e-04 -1.064032e-04
## ASV0962     -4.700002e-38 -2.868549e-04 -3.002279e-04
## ASV0794      8.164808e-38  5.249160e-04  5.505655e-04
## ASV7117     -8.319600e-38 -5.031441e-04 -5.263567e-04
## ASV1008     -3.793214e-38 -2.386200e-04 -2.500314e-04
## ASV0096      9.988539e-38  6.153921e-04  6.444092e-04
## ASV0128     -1.612000e-37 -1.008053e-03 -1.056185e-03
## ASV5232      1.454276e-37  9.231295e-04  9.677539e-04
## ASV0031     -1.157024e-38 -7.200799e-05 -7.546890e-05
## ASV1744     -1.586971e-37 -9.818072e-04 -1.028444e-03
## ASV0289      4.520361e-38  2.776967e-04  2.907243e-04
## ASV7413     -1.905808e-38 -1.471757e-04 -1.553910e-04
## ASV0822     -2.063278e-37 -1.240163e-03 -1.297087e-03
## ASV8111     -3.427709e-37 -2.051247e-03 -2.145275e-03
## ASV0687      4.167534e-38  2.618030e-04  2.743085e-04
## ASV0112     -1.515135e-38 -9.541727e-05 -9.997165e-05
## ASV0987      5.148582e-38  3.233002e-04  3.387799e-04
## ASV5332     -4.314002e-38 -2.197817e-04 -2.281060e-04
## ASV1129     -9.721737e-38 -5.985502e-04 -6.266883e-04
## ASV1274     -2.710155e-38 -1.659460e-04 -1.737064e-04
## ASV0119      6.486660e-38  3.992565e-04  4.180606e-04
## ASV0890     -3.170310e-39 -2.049734e-05 -2.150757e-05
## ASV0848     -1.205152e-37 -7.413454e-04 -7.764155e-04
## ASV5944     -5.380769e-37 -3.275723e-03 -3.428193e-03
## ASV19741    -1.953147e-37 -1.192982e-03 -1.248551e-03
## ASV0504     -2.520239e-37 -1.514163e-03 -1.583580e-03
## ASV2146     -1.864004e-37 -1.100899e-03 -1.150419e-03
## ASV0089     -4.141380e-38 -2.537751e-04 -2.656740e-04
## ASV2301     -6.611146e-38 -4.096032e-04 -4.289820e-04
## ASV2982     -1.351219e-36 -7.491748e-03 -7.805904e-03
## ASV0891     -7.832928e-38 -4.802519e-04 -5.027526e-04
## ASV0093      8.622854e-38  5.258208e-04  5.503852e-04
## ASV0042      2.980870e-38  1.835453e-04  1.921735e-04
## ASV0980      1.015460e-37  6.034649e-04  6.307872e-04
## ASV0069     -4.550192e-38 -2.802449e-04 -2.934656e-04
## ASV1364     -3.562545e-38 -2.163244e-04 -2.263381e-04
## ASV0524     -1.731138e-37 -1.074760e-03 -1.125621e-03
## ASV0435      2.387541e-37  1.475291e-03  1.544861e-03
## ASV0517     -4.727645e-38 -2.914640e-04 -3.051572e-04
## ASV3167     -3.142183e-37 -2.058518e-03 -2.161171e-03
## ASV4280     -2.177095e-37 -1.335480e-03 -1.397949e-03
## ASV1158      7.039571e-38  4.635863e-04  4.867175e-04
## ASV2214      7.631016e-38  4.523075e-04  4.727542e-04
## ASV0544     -1.153800e-37 -7.205621e-04 -7.548927e-04
## ASV5326     -1.581776e-38 -1.000064e-04 -1.048803e-04
## ASV3765     -9.235149e-38 -5.656565e-04 -5.921085e-04
## ASV4646      7.944306e-39  1.634093e-05  1.575430e-05
## ASV0090      7.937057e-39  4.538548e-05  4.734479e-05
## ASV3680      1.608251e-37  9.496298e-04  9.922970e-04
## ASV0111      1.656553e-38  9.921313e-05  1.037227e-04
## ASV0768      2.198746e-38  1.389641e-04  1.456728e-04
## ASV4862     -1.573686e-38 -8.527794e-05 -8.870057e-05
## ASV1742     -1.377010e-37 -8.292856e-04 -8.674273e-04
## ASV3701     -5.619869e-38 -3.163943e-04 -3.300000e-04
## ASV2386     -2.507241e-37 -1.558864e-03 -1.634118e-03
## ASV0375     -1.846821e-37 -1.115449e-03 -1.166801e-03
## ASV2796      6.693804e-38  3.900670e-04  4.073618e-04
## ASV1369      1.473735e-37  8.697571e-04  9.089010e-04
## ASV10272    -2.053603e-37 -1.255309e-03 -1.314483e-03
## ASV10354    -3.058456e-37 -1.869547e-03 -1.957530e-03
## ASV1067      1.013222e-37  6.151499e-04  6.428497e-04
## ASV1900      1.621175e-37  1.001497e-03  1.048724e-03
## ASV4079     -6.959005e-38 -4.492247e-04 -4.717623e-04
## ASV4149      3.360885e-37  1.997342e-03  2.087716e-03
## ASV5140     -3.058456e-37 -1.869547e-03 -1.957433e-03
## ASV10782     5.886497e-39  5.650594e-05  5.980365e-05
## ASV4273     -3.311479e-38 -1.846267e-04 -1.927523e-04
## ASV8121      1.370259e-37  8.408254e-04  8.800666e-04
## ASV8438     -3.479804e-37 -2.127106e-03 -2.226976e-03
## ASV9390     -3.479804e-37 -2.127106e-03 -2.226812e-03
## ASV1340      2.765142e-37  1.708696e-03  1.789261e-03
## ASV2650     -6.507243e-37 -3.960332e-03 -4.144624e-03
## ASV4674      1.735831e-37  1.057070e-03  1.106070e-03
## ASV10492     4.434544e-39  1.977126e-05  2.026954e-05
## ASV11430    -2.655735e-37 -1.623375e-03 -1.699302e-03
## ASV12135    -2.655735e-37 -1.623375e-03 -1.699177e-03
## ASV14970    -3.266095e-37 -1.996471e-03 -2.089541e-03
## ASV1954      3.958336e-37  2.423955e-03  2.537160e-03
## ASV2613      2.517857e-37  1.535264e-03  1.606601e-03
## ASV2757      1.615939e-37  9.613802e-04  1.004954e-03
## ASV2909     -4.565990e-37 -2.838410e-03 -2.973009e-03
## ASV2954     -1.739621e-38 -1.071091e-04 -1.121982e-04
## ASV2969      1.174792e-37  7.268237e-04  7.611442e-04
## ASV3410      4.097552e-38  2.565295e-04  2.686931e-04
## ASV3575      8.221096e-38  4.965481e-04  5.193402e-04
## ASV4275      2.131955e-37  1.277144e-03  1.335325e-03
## ASV4652      4.351763e-38  2.714914e-04  2.842304e-04
## ASV4761      1.547781e-37  9.262163e-04  9.683689e-04
## ASV6003      1.063178e-37  6.679857e-04  6.999678e-04
## ASV6110     -7.493063e-37 -4.580298e-03 -4.794555e-03
## ASV7427      1.321422e-37  7.987203e-04  8.354328e-04
## ASV8092     -2.457270e-37 -1.502060e-03 -1.572247e-03
## ASV8169     -7.493063e-37 -4.580298e-03 -4.793971e-03
## ASV9693      1.277408e-37  7.781458e-04  8.142312e-04
## ASV10913     8.394460e-38  5.197660e-04  5.444498e-04
## ASV1979      7.686665e-38  4.637261e-04  4.849981e-04
## ASV3772      1.592468e-37  9.584243e-04  1.002367e-03
## ASV0113     -2.056327e-38 -1.274593e-04 -1.334889e-04
## ASV1800     -2.691127e-38 -1.681026e-04 -1.760881e-04
## ASV2335     -5.844772e-37 -3.529482e-03 -3.692307e-03
## ASV0692     -3.694013e-39 -2.344888e-05 -2.460019e-05
## ASV1120      2.022043e-38  1.261690e-04  1.321401e-04
## ASV1434     -1.021158e-37 -6.292450e-04 -6.588330e-04
## ASV0076     -4.793051e-38 -2.949952e-04 -3.088528e-04
## ASV0361      1.703294e-37  1.051999e-03  1.101590e-03
## ASV2231     -5.179415e-38 -3.341106e-04 -3.505926e-04
## ASV2018     -1.377569e-38 -8.462158e-05 -8.860079e-05
## ASV1529      7.269140e-38  4.541226e-04  4.757802e-04
## ASV0841     -2.614525e-38 -1.596352e-04 -1.670686e-04
## ASV2556     -4.758581e-37 -2.923827e-03 -3.060886e-03
## ASV2777      1.675395e-37  9.828180e-04  1.026598e-03
## ASV0355      1.189220e-37  7.289754e-04  7.630707e-04
## ASV5169     -1.425839e-37 -8.724290e-04 -9.131837e-04
## ASV3091      1.318115e-37  8.181942e-04  8.569629e-04
## ASV2435      5.449840e-38  3.325703e-04  3.480653e-04
## ASV6822     -2.942060e-37 -1.798971e-03 -1.882818e-03
## ASV12605    -2.829431e-37 -1.746426e-03 -1.828554e-03
## ASV0286     -6.889050e-38 -4.206311e-04 -4.402293e-04
## ASV0074     -2.671419e-38 -1.655397e-04 -1.733697e-04
## ASV2485     -9.831017e-39 -6.722783e-05 -7.074722e-05
## ASV1233     -2.123672e-37 -1.311040e-03 -1.372821e-03
## ASV0356     -5.772665e-38 -3.495212e-04 -3.656565e-04
## ASV2918     -2.399506e-37 -1.465581e-03 -1.533810e-03
## ASV1427     -2.859189e-38 -1.812614e-04 -1.900278e-04
## ASV1409      5.133973e-38  3.208451e-04  3.361428e-04
## ASV0770      1.721349e-38  1.024091e-04  1.070371e-04
## ASV1403     -1.471209e-37 -9.016516e-04 -9.437692e-04
## ASV0314     -5.195019e-38 -3.141032e-04 -3.285652e-04
## ASV0187     -1.445215e-38 -9.105148e-05 -9.542528e-05
## ASV0313     -7.327158e-38 -4.453709e-04 -4.660208e-04
## ASV1087      1.667204e-37  1.023110e-03  1.070992e-03
## ASV1970     -2.545699e-38 -1.557371e-04 -1.630177e-04
## ASV0754      1.826246e-37  1.124737e-03  1.177595e-03
## ASV3775     -4.329655e-38 -2.682881e-04 -2.809678e-04
## ASV0132     -3.156685e-38 -1.940743e-04 -2.031714e-04
## ASV2329      2.552733e-38  1.191180e-04  1.229263e-04
## ASV0561      4.848264e-38  2.895219e-04  3.026773e-04
## ASV0130     -9.511514e-38 -5.860302e-04 -6.135732e-04
## ASV0226      1.208173e-37  7.399736e-04  7.745837e-04
## ASV12648    -1.725456e-37 -1.042277e-03 -1.090294e-03
## ASV0204      1.162478e-37  7.121260e-04  7.453850e-04
## ASV0767     -5.384427e-38 -3.411765e-04 -3.576749e-04
## ASV0335     -1.085274e-37 -6.635239e-04 -6.944341e-04
## ASV5901     -2.495390e-38 -1.470216e-04 -1.536240e-04
## ASV0596     -1.731983e-39 -2.796886e-06 -2.545736e-06
## ASV9271      7.967192e-38  5.242689e-04  5.504570e-04
## ASV0904      6.860958e-38  4.272139e-04  4.475198e-04
## ASV15270    -4.057138e-38 -2.733445e-04 -2.872546e-04
## ASV0990     -3.815407e-38 -2.364822e-04 -2.476628e-04
## ASV0155     -8.023859e-38 -4.925366e-04 -5.155843e-04
## ASV0086     -1.595863e-38 -9.817926e-05 -1.027858e-04
## ASV2581     -8.247855e-39 -4.829425e-05 -5.043668e-05
## ASV1579     -6.408492e-38 -4.004131e-04 -4.194933e-04
## ASV7730      6.849012e-53 -1.750436e-05 -1.909984e-05
## ASV0897      9.380923e-39  5.965481e-05  6.254672e-05
## ASV1975      4.490421e-37  2.757185e-03  2.886308e-03
coef(best_model_1000)
## 1001 x 100 sparse Matrix of class "dgCMatrix"
##   [[ suppressing 32 column names 's0', 's1', 's2' ... ]]
##                                                                    
## (Intercept) -1.249001e-16  8.559541e-03  8.966024e-03  9.386331e-03
## ASV1236      2.313137e-37  1.394100e-03  1.460363e-03  1.527409e-03
## ASV0421     -1.103570e-37 -6.609057e-04 -6.923665e-04 -7.238944e-04
## ASV0691     -2.330527e-37 -1.364898e-03 -1.429777e-03 -1.493308e-03
## ASV0899      1.300837e-37  8.053254e-04  8.436280e-04  8.834471e-04
## ASV1004      5.196804e-37  3.138310e-03  3.287476e-03  3.438638e-03
## ASV1041     -3.153556e-37 -1.915427e-03 -2.006359e-03 -2.099209e-03
## ASV1058      3.238329e-37  1.955540e-03  2.048373e-03  2.142559e-03
## ASV12542     1.240721e-37  7.404594e-04  7.757174e-04  8.109141e-04
## ASV1294      2.713433e-37  1.643319e-03  1.721342e-03  1.800745e-03
## ASV13113     9.227698e-38  5.774566e-04  6.049308e-04  6.338108e-04
## ASV1318      2.974952e-37  1.800155e-03  1.885561e-03  1.972473e-03
## ASV2269     -5.011790e-37 -3.052902e-03 -3.196991e-03 -3.345528e-03
## ASV2542      2.166652e-37  1.338551e-03  1.402068e-03  1.468135e-03
## ASV2660     -2.252494e-37 -1.361489e-03 -1.425811e-03 -1.491472e-03
## ASV2737      4.487411e-38  2.562562e-04  2.686682e-04  2.802335e-04
## ASV2840      2.859513e-37  1.713695e-03  1.794856e-03  1.876682e-03
## ASV3053      2.397345e-36  1.442345e-02  1.510463e-02  1.579621e-02
## ASV3077      8.480135e-38  5.085396e-04  5.326100e-04  5.568958e-04
## ASV3134      1.549578e-37  9.624004e-04  1.008170e-03  1.055928e-03
## ASV3140      1.913464e-37  1.177401e-03  1.233147e-03  1.291018e-03
## ASV3579      6.046585e-38  3.807353e-04  3.989826e-04  4.181333e-04
## ASV6119     -1.368029e-37 -8.333249e-04 -8.725745e-04 -9.131102e-04
## ASV7557     -2.783073e-37 -1.695289e-03 -1.775006e-03 -1.857459e-03
## ASV8422      6.409379e-38  3.771121e-04  3.952726e-04  4.129237e-04
## ASV1086     -1.565806e-38 -9.052144e-05 -9.482473e-05 -9.895811e-05
## ASV1310      1.200270e-37  7.246213e-04  7.590342e-04  7.939211e-04
## ASV15750    -2.058606e-38 -1.245425e-04 -1.303068e-04 -1.363204e-04
## ASV16905    -5.713590e-38 -3.480387e-04 -3.644019e-04 -3.813274e-04
## ASV2033      2.475958e-37  1.523486e-03  1.596089e-03  1.670954e-03
## ASV2089      1.041249e-37  6.358152e-04  6.656991e-04  6.967052e-04
## ASV2127      3.997226e-37  2.412485e-03  2.526882e-03  2.643013e-03
## ASV2725      3.236290e-37  1.938749e-03  2.030791e-03  2.123351e-03
## ASV2804     -1.183344e-37 -7.208237e-04 -7.546912e-04 -7.897425e-04
## ASV3075      2.672760e-37  1.618234e-03  1.695132e-03  1.773311e-03
## ASV3327      3.570452e-37  2.193278e-03  2.297819e-03  2.405429e-03
## ASV3342      2.948194e-37  1.808894e-03  1.894651e-03  1.983287e-03
## ASV3532     -3.344720e-37 -2.057244e-03 -2.154334e-03 -2.255396e-03
## ASV3600      1.527223e-37  9.304155e-04  9.746890e-04  1.019934e-03
## ASV4013      2.977252e-37  1.802898e-03  1.888492e-03  1.975579e-03
## ASV4136      3.320250e-37  1.991843e-03  2.086027e-03  2.181300e-03
## ASV4195      1.196262e-36  7.286922e-03  7.628608e-03  7.982875e-03
## ASV4407     -4.679698e-37 -2.850594e-03 -2.984040e-03 -3.122607e-03
## ASV4717      5.230493e-38  2.890044e-04  3.034034e-04  3.159528e-04
## ASV6794      1.926202e-37  1.133281e-03  1.187377e-03  1.240431e-03
## ASV8324     -2.397177e-37 -1.460217e-03 -1.528574e-03 -1.599546e-03
## ASV8981     -9.113278e-39 -5.241488e-05 -5.467353e-05 -5.705381e-05
## ASV9859      6.805349e-38  4.340526e-04  4.549901e-04  4.771286e-04
## ASV0936      1.622018e-38  1.101252e-04  1.150230e-04  1.209697e-04
## ASV12683    -4.432161e-39 -3.348258e-05 -3.480415e-05 -3.676269e-05
## ASV1293      1.527595e-37  9.213838e-04  9.649394e-04  1.009262e-03
## ASV13055    -8.706304e-39 -5.125634e-05 -5.329826e-05 -5.568080e-05
## ASV17063    -1.242972e-37 -7.571430e-04 -7.924237e-04 -8.292090e-04
## ASV2228      1.012017e-37  6.164589e-04  6.451370e-04  6.750828e-04
## ASV2769      9.716036e-39  6.036428e-05  6.358468e-05  6.659363e-05
## ASV2803      9.455162e-38  5.557170e-04  5.823590e-04  6.083437e-04
## ASV2896      8.356686e-38  5.108955e-04  5.353061e-04  5.602568e-04
## ASV3062      8.777758e-38  5.453552e-04  5.718076e-04  5.988946e-04
## ASV3107      1.667808e-37  1.022760e-03  1.071443e-03  1.121529e-03
## ASV3265      2.359002e-37  1.422091e-03  1.489316e-03  1.557664e-03
## ASV3666      1.340054e-39  5.578262e-06  6.164995e-06  6.313274e-06
## ASV4497      7.160688e-38  4.320072e-04  4.527005e-04  4.734926e-04
## ASV6914     -1.543954e-38 -1.005464e-04 -1.050622e-04 -1.102809e-04
## ASV0576     -3.112524e-37 -1.843308e-03 -1.930661e-03 -2.017560e-03
## ASV0673      2.198679e-37  1.347284e-03  1.411098e-03  1.476991e-03
## ASV0772      1.291034e-37  7.816118e-04  8.187864e-04  8.565413e-04
## ASV0862     -2.458659e-38 -1.335368e-04 -1.397524e-04 -1.453817e-04
## ASV0898      9.047621e-38  5.628762e-04  5.896462e-04  6.176271e-04
## ASV0910      1.133405e-37  6.981760e-04  7.313287e-04  7.656771e-04
## ASV0964     -1.222272e-37 -7.309320e-04 -7.655512e-04 -8.003635e-04
## ASV10059     7.868340e-38  4.914020e-04  5.149129e-04  5.394481e-04
## ASV10263    -1.892670e-37 -1.152897e-03 -1.207113e-03 -1.263144e-03
## ASV1088      1.831116e-37  1.124283e-03  1.177711e-03  1.232863e-03
## ASV1101      2.225452e-37  1.344589e-03  1.408201e-03  1.472973e-03
## ASV1183      6.577420e-38  4.050347e-04  4.241337e-04  4.440496e-04
## ASV11956     6.369100e-38  3.670147e-04  3.846346e-04  4.014186e-04
## ASV12774     8.458601e-40 -2.760981e-06 -2.782851e-06 -3.326459e-06
## ASV1321      2.821092e-37  1.738417e-03  1.821302e-03  1.906863e-03
## ASV13793    -1.304459e-37 -7.945951e-04 -8.319266e-04 -8.705367e-04
## ASV14482     3.530656e-39  1.245270e-05  1.315951e-05  1.330585e-05
## ASV15483     4.778735e-38  2.926410e-04  3.066757e-04  3.209946e-04
## ASV2062      2.419400e-37  1.470145e-03  1.539617e-03  1.610886e-03
## ASV2132      2.064836e-37  1.270260e-03  1.330744e-03  1.393167e-03
## ASV2413      1.933389e-37  1.163967e-03  1.218933e-03  1.274795e-03
## ASV2490      6.089161e-37  3.629632e-03  3.800919e-03  3.973226e-03
## ASV2594      6.907828e-38  4.182005e-04  4.380220e-04  4.582276e-04
## ASV2822     -3.447005e-37 -2.099700e-03 -2.198653e-03 -2.300696e-03
## ASV2863      3.806829e-37  2.288579e-03  2.396155e-03  2.505808e-03
## ASV2910      1.321773e-37  7.933841e-04  8.310227e-04  8.689852e-04
## ASV2980      1.250029e-37  7.629922e-04  7.989479e-04  8.361076e-04
## ASV3307      2.730686e-37  1.663362e-03  1.741518e-03  1.822334e-03
## ASV3474      1.616732e-37  9.993295e-04  1.046900e-03  1.096249e-03
## ASV3502      1.993020e-37  1.215917e-03  1.273562e-03  1.332773e-03
## ASV4236      2.974774e-37  1.785219e-03  1.868809e-03  1.954119e-03
## ASV4842     -5.297937e-38 -3.388126e-04 -3.549107e-04 -3.722049e-04
## ASV4894     -1.304459e-37 -7.945941e-04 -8.320065e-04 -8.706171e-04
## ASV5290      1.032380e-37  6.295356e-04  6.595440e-04  6.901998e-04
## ASV5501      5.210114e-38  3.154824e-04  3.303683e-04  3.456046e-04
## ASV5795      6.306093e-38  3.847774e-04  4.030567e-04  4.217994e-04
## ASV5987     -3.649535e-37 -2.223066e-03 -2.327849e-03 -2.435878e-03
## ASV6267     -4.113963e-37 -2.505966e-03 -2.623889e-03 -2.745650e-03
## ASV6862      1.746877e-37  1.038615e-03  1.087676e-03  1.136851e-03
## ASV7145      6.876014e-38  3.965433e-04  4.150898e-04  4.332167e-04
## ASV7673     -1.304459e-37 -7.945936e-04 -8.319721e-04 -8.705770e-04
## ASV7789      5.210997e-38  3.274531e-04  3.431935e-04  3.596471e-04
## ASV7809     -3.236514e-39 -1.736248e-05 -1.800547e-05 -1.871298e-05
## ASV8002     -1.647947e-37 -1.003824e-03 -1.051005e-03 -1.099772e-03
## ASV8205      5.628364e-38  3.388780e-04  3.551458e-04  3.714403e-04
## ASV9155     -4.555355e-38 -2.767566e-04 -2.896835e-04 -3.030832e-04
## ASV9221      4.624289e-39  2.537940e-05  2.689302e-05  2.800204e-05
## ASV9311     -2.645711e-37 -1.611598e-03 -1.687225e-03 -1.765504e-03
## ASV9557     -1.807136e-37 -1.100792e-03 -1.152363e-03 -1.205824e-03
## ASV9936     -3.649535e-37 -2.223063e-03 -2.327041e-03 -2.434990e-03
## ASV1445      2.371269e-37  1.450023e-03  1.518918e-03  1.589709e-03
## ASV4232      1.031736e-37  6.378912e-04  6.683295e-04  6.998550e-04
## ASV6479      1.207169e-38  8.873740e-05  9.324463e-05  9.838010e-05
## ASV0142     -1.543844e-37 -9.265613e-04 -9.702822e-04 -1.014599e-03
## ASV0378     -9.024721e-39 -4.516801e-05 -4.709691e-05 -4.875846e-05
## ASV1122      2.326086e-37  1.425385e-03  1.493038e-03  1.562782e-03
## ASV0123     -1.367790e-37 -8.203329e-04 -8.589734e-04 -8.981756e-04
## ASV2064      8.100367e-38  4.752077e-04  4.975054e-04  5.196865e-04
## ASV4459     -3.271681e-38 -2.043887e-04 -2.139440e-04 -2.241311e-04
## ASV0448      4.831431e-38  3.037807e-04  3.183378e-04  3.336067e-04
## ASV0397      1.083716e-37  6.630086e-04  6.944923e-04  7.268749e-04
## ASV0485      1.441358e-37  8.737148e-04  9.150310e-04  9.572806e-04
## ASV1566      2.270274e-37  1.382816e-03  1.448301e-03  1.515517e-03
## ASV1365      1.466433e-37  8.876752e-04  9.298099e-04  9.726796e-04
## ASV1065      2.712034e-37  1.657682e-03  1.736077e-03  1.816948e-03
## ASV0722     -1.563383e-38 -9.532325e-05 -9.990116e-05 -1.045523e-04
## ASV12660    -1.522608e-37 -9.175453e-04 -9.608047e-04 -1.004870e-03
## ASV0223      2.278950e-38  1.393713e-04  1.459451e-04  1.527455e-04
## ASV0229      5.560127e-38  3.435098e-04  3.598016e-04  3.767501e-04
## ASV0877      7.526500e-39  3.654254e-05  3.864099e-05  3.998844e-05
## ASV0983      1.469405e-37  8.874245e-04  9.293185e-04  9.720465e-04
## ASV0626     -1.441585e-38 -7.438319e-05 -7.746473e-05 -8.035456e-05
## ASV4146     -7.067638e-39 -4.722935e-05 -4.912421e-05 -5.161160e-05
## ASV4175     -1.727823e-37 -1.060025e-03 -1.109946e-03 -1.161837e-03
## ASV2082     -7.687000e-38 -4.867694e-04 -5.104888e-04 -5.351813e-04
## ASV2272      7.987959e-38  4.842595e-04  5.072806e-04  5.307154e-04
## ASV2245     -1.256358e-37 -7.717385e-04 -8.080287e-04 -8.458516e-04
## ASV0590     -9.858070e-38 -6.263833e-04 -6.567938e-04 -6.886611e-04
## ASV0217     -1.844218e-38 -9.253090e-05 -9.660567e-05 -1.000603e-04
## ASV0416      1.038749e-37  6.145003e-04  6.432341e-04  6.721285e-04
## ASV1056      1.101317e-37  6.813088e-04  7.138788e-04  7.475640e-04
## ASV7777     -1.667846e-37 -1.028871e-03 -1.077234e-03 -1.127891e-03
## ASV0455      2.146648e-38  1.313842e-04  1.374896e-04  1.438948e-04
## ASV0604      6.562340e-38  4.110815e-04  4.309004e-04  4.514957e-04
## ASV6100     -1.181295e-37 -7.293995e-04 -7.637175e-04 -7.996642e-04
## ASV11359    -2.691605e-37 -1.642709e-03 -1.719690e-03 -1.799617e-03
## ASV6604      4.713687e-38  2.918813e-04  3.058769e-04  3.203282e-04
## ASV5004     -7.566846e-38 -4.658588e-04 -4.875782e-04 -5.104495e-04
## ASV1483     -4.705807e-38 -2.921389e-04 -3.056769e-04 -3.201348e-04
## ASV9773     -1.185726e-37 -7.294351e-04 -7.637104e-04 -7.995155e-04
## ASV4059      8.416279e-38  5.303008e-04  5.559560e-04  5.827003e-04
## ASV1193      1.464229e-37  8.917042e-04  9.339957e-04  9.773416e-04
## ASV4610     -2.376196e-38 -1.312592e-04 -1.370502e-04 -1.426931e-04
## ASV0742     -3.662341e-38 -2.092892e-04 -2.186451e-04 -2.280659e-04
## ASV1502      6.398060e-39  2.845071e-05  2.989744e-05  3.075129e-05
## ASV0195     -3.974510e-39 -2.879880e-05 -3.029422e-05 -3.194540e-05
## ASV1213      1.288220e-37  7.722457e-04  8.080001e-04  8.448317e-04
## ASV1648     -1.108567e-37 -6.836676e-04 -7.157613e-04 -7.494091e-04
## ASV6984     -1.032657e-37 -6.368995e-04 -6.666829e-04 -6.980153e-04
## ASV0396     -1.600111e-38 -8.078363e-05 -8.454993e-05 -8.762822e-05
## ASV4297      1.808061e-37  1.082104e-03  1.133443e-03  1.185076e-03
## ASV2622      2.354412e-37  1.418260e-03  1.485196e-03  1.553309e-03
## ASV3512      7.623514e-38  4.766368e-04  4.997039e-04  5.235584e-04
## ASV2411      1.381701e-37  8.540141e-04  8.944367e-04  9.365825e-04
## ASV2291     -6.825968e-38 -4.376772e-04 -4.594826e-04 -4.819979e-04
## ASV0807      1.585891e-37  9.837712e-04  1.030504e-03  1.079230e-03
## ASV1292      5.570144e-38  3.344484e-04  3.498717e-04  3.658397e-04
## ASV1035      1.594171e-37  9.576366e-04  1.002512e-03  1.048324e-03
## ASV0070     -7.087068e-39 -3.729078e-05 -3.898988e-05 -4.049511e-05
## ASV0255      1.574191e-38  9.247448e-05  9.672461e-05  1.010245e-04
## ASV0057     -5.990433e-38 -3.563231e-04 -3.730405e-04 -3.899089e-04
## ASV0077     -1.112193e-38 -6.301965e-05 -6.594891e-05 -6.876686e-05
## ASV0625      1.156712e-37  6.933558e-04  7.258437e-04  7.589372e-04
## ASV2464      7.722532e-37  4.632964e-03  4.849928e-03  5.071197e-03
## ASV1315      2.217288e-37  1.354858e-03  1.419356e-03  1.485510e-03
## ASV2673      1.851008e-37  1.149128e-03  1.203957e-03  1.260979e-03
## ASV2161      7.994847e-38  4.945589e-04  5.182244e-04  5.426873e-04
## ASV0337     -4.359738e-38 -2.669863e-04 -2.797262e-04 -2.927898e-04
## ASV7680     -2.690768e-37 -1.659102e-03 -1.737173e-03 -1.818814e-03
## ASV0611      1.410551e-37  8.688300e-04  9.101311e-04  9.528801e-04
## ASV3118     -1.649758e-37 -1.026159e-03 -1.074531e-03 -1.125484e-03
## ASV1284      1.060834e-37  6.619875e-04  6.921362e-04  7.249163e-04
## ASV0889      1.060661e-37  6.389689e-04  6.693131e-04  7.000250e-04
## ASV4649     -5.757771e-38 -3.533187e-04 -3.698486e-04 -3.871391e-04
## ASV1108     -1.261088e-37 -7.891387e-04 -8.265248e-04 -8.659682e-04
## ASV0738      2.261826e-38  1.645518e-04  1.725559e-04  1.819507e-04
## ASV0473     -1.065807e-38 -7.092254e-05 -7.455896e-05 -7.834714e-05
## ASV0598     -8.015355e-38 -4.793041e-04 -5.021372e-04 -5.249952e-04
## ASV0429      1.126749e-37  6.814821e-04  7.136322e-04  7.464944e-04
## ASV1549      1.400120e-37  8.715199e-04  9.130075e-04  9.563613e-04
## ASV1203      1.233861e-37  7.464643e-04  7.814888e-04  8.174841e-04
## ASV4532      3.210107e-39  1.372302e-05  1.440565e-05  1.478205e-05
## ASV0274     -2.161423e-38 -1.210016e-04 -1.266848e-04 -1.320325e-04
## ASV0163     -1.053436e-37 -6.301363e-04 -6.595647e-04 -6.895754e-04
## ASV1298      4.374301e-38  2.599296e-04  2.718149e-04  2.840836e-04
## ASV9424     -2.313698e-37 -1.429064e-03 -1.496406e-03 -1.566866e-03
## ASV0412      2.058934e-37  1.246689e-03  1.305488e-03  1.365675e-03
## ASV0284      5.384175e-38  3.169372e-04  3.316365e-04  3.464440e-04
## ASV0620     -5.010541e-38 -3.220995e-04 -3.373486e-04 -3.538734e-04
## ASV0153     -1.587864e-37 -9.856560e-04 -1.032848e-03 -1.081768e-03
## ASV0498      5.976205e-38  3.758388e-04  3.936122e-04  4.124676e-04
## ASV0097      4.121802e-38  2.553882e-04  2.675041e-04  2.801475e-04
## ASV0104     -2.823673e-37 -1.716999e-03 -1.798462e-03 -1.881807e-03
## ASV1282      7.314477e-38  4.501119e-04  4.714658e-04  4.935449e-04
## ASV3883     -7.998682e-38 -5.016141e-04 -5.253733e-04 -5.504889e-04
## ASV0801      5.102516e-38  3.206509e-04  3.355718e-04  3.516421e-04
## ASV1611     -1.887315e-37 -1.166342e-03 -1.221449e-03 -1.278999e-03
## ASV0227     -3.826857e-38 -2.431090e-04 -2.548767e-04 -2.672362e-04
## ASV0833      5.459195e-38  3.364231e-04  3.523836e-04  3.689425e-04
## ASV0718      2.694436e-37  1.652089e-03  1.730193e-03  1.811047e-03
## ASV1139      4.121910e-38  2.375966e-04  2.483900e-04  2.592008e-04
## ASV0766     -4.481193e-38 -2.808931e-04 -2.941222e-04 -3.081796e-04
## ASV2091      2.927985e-37  1.747840e-03  1.830097e-03  1.913221e-03
## ASV1238     -1.097994e-37 -6.321833e-04 -6.616482e-04 -6.905859e-04
## ASV9193     -2.467671e-38 -1.958827e-04 -2.049129e-04 -2.166467e-04
## ASV0290      7.113213e-39  3.661694e-05  3.830783e-05  3.974396e-05
## ASV0231      8.988991e-38  5.450948e-04  5.706928e-04  5.970404e-04
## ASV0185      2.877618e-38  1.931398e-04  2.024846e-04  2.128029e-04
## ASV2330      8.622386e-38  5.126747e-04  5.367629e-04  5.610246e-04
## ASV3119     -4.174620e-38 -2.700638e-04 -2.830020e-04 -2.969537e-04
## ASV2368     -1.160028e-37 -7.229232e-04 -7.570413e-04 -7.930210e-04
## ASV0122     -4.085792e-38 -2.449189e-04 -2.565776e-04 -2.682922e-04
## ASV1044      1.240979e-37  7.748314e-04  8.117206e-04  8.503839e-04
## ASV0160     -7.023484e-38 -4.156715e-04 -4.351160e-04 -4.546911e-04
## ASV0326      1.906459e-38  1.162767e-04  1.218641e-04  1.275315e-04
## ASV1388      3.361188e-37  2.042972e-03  2.139630e-03  2.238719e-03
## ASV0792      2.062546e-37  1.245583e-03  1.303961e-03  1.363901e-03
## ASV0036     -5.161936e-38 -3.197732e-04 -3.350740e-04 -3.509104e-04
## ASV2125      1.866811e-37  1.132937e-03  1.186534e-03  1.241390e-03
## ASV1075      8.440824e-39  5.254519e-05  5.515214e-05  5.777898e-05
## ASV0390      9.476759e-38  5.950666e-04  6.232740e-04  6.531258e-04
## ASV3790     -1.506360e-37 -9.226496e-04 -9.661469e-04 -1.011253e-03
## ASV1535     -2.297414e-38 -1.575264e-04 -1.650600e-04 -1.736081e-04
## ASV0263      1.375848e-37  8.399352e-04  8.793609e-04  9.202449e-04
## ASV0675      2.581611e-37  1.598271e-03  1.674006e-03  1.753022e-03
## ASV3348      2.636365e-38  1.664014e-04  1.745167e-04  1.829311e-04
## ASV0058     -9.080383e-38 -5.466377e-04 -5.724450e-04 -5.986902e-04
## ASV4142      1.085380e-37  6.552869e-04  6.859309e-04  7.174694e-04
## ASV0059     -7.555678e-38 -4.533993e-04 -4.747556e-04 -4.964462e-04
## ASV0013     -1.012731e-37 -6.173734e-04 -6.465967e-04 -6.766402e-04
## ASV0033     -4.906090e-38 -3.042730e-04 -3.187863e-04 -3.338690e-04
## ASV4354     -6.721233e-38 -4.117571e-04 -4.311635e-04 -4.512903e-04
## ASV0022     -3.867359e-38 -2.402023e-04 -2.516322e-04 -2.635546e-04
## ASV0134     -4.132029e-38 -2.587064e-04 -2.710611e-04 -2.840162e-04
## ASV0415      9.518276e-40  1.768292e-05  1.860486e-05  2.006636e-05
## ASV10103    -2.344283e-37 -1.448356e-03 -1.516491e-03 -1.587903e-03
## ASV1613      1.881773e-37  1.133817e-03  1.187062e-03  1.241503e-03
## ASV0135     -3.181329e-38 -1.878567e-04 -1.965798e-04 -2.053915e-04
## ASV0469     -2.371467e-37 -1.431357e-03 -1.498391e-03 -1.567252e-03
## ASV0471      1.669730e-37  1.030988e-03  1.079610e-03  1.130407e-03
## ASV0451     -2.199776e-38 -1.452445e-04 -1.524137e-04 -1.600860e-04
## ASV0747      5.757427e-38  3.589770e-04  3.760051e-04  3.938771e-04
## ASV1314     -7.145632e-38 -4.473703e-04 -4.686158e-04 -4.909970e-04
## ASV0425     -3.468560e-37 -2.068554e-03 -2.165574e-03 -2.263843e-03
## ASV0559     -9.661613e-38 -5.818120e-04 -6.092101e-04 -6.371604e-04
## ASV0148     -5.648886e-38 -3.323415e-04 -3.478918e-04 -3.634383e-04
## ASV0129     -2.156876e-38 -1.126036e-04 -1.176951e-04 -1.222045e-04
## ASV1072      4.025820e-38  2.349337e-04  2.459091e-04  2.568047e-04
## ASV2390      1.320843e-37  7.862453e-04  8.231079e-04  8.603581e-04
## ASV0548      1.115593e-37  6.801092e-04  7.123186e-04  7.454216e-04
## ASV0168     -7.664324e-38 -4.617167e-04 -4.834285e-04 -5.056098e-04
## ASV0066     -6.179368e-38 -3.764217e-04 -3.942126e-04 -4.125109e-04
## ASV0468     -3.954795e-38 -2.424289e-04 -2.538221e-04 -2.656788e-04
## ASV0172     -2.112259e-38 -1.204400e-04 -1.259960e-04 -1.314270e-04
## ASV0236     -4.232393e-38 -2.314898e-04 -2.419536e-04 -2.518478e-04
## ASV0250      3.354387e-38  2.314324e-04  2.427734e-04  2.554237e-04
## ASV0338      3.517291e-38  2.284010e-04  2.393896e-04  2.512161e-04
## ASV0450     -2.462393e-39 -1.814394e-05 -1.907166e-05 -2.012616e-05
## ASV0377      8.540282e-38  5.206318e-04  5.451617e-04  5.704779e-04
## ASV1022      1.087405e-38  6.700126e-05  7.010695e-05  7.339676e-05
## ASV6174     -9.225827e-39 -5.937362e-05 -6.221835e-05 -6.526164e-05
## ASV0786      9.516520e-39  5.165487e-05  5.395435e-05  5.611857e-05
## ASV0053     -7.792030e-38 -4.784080e-04 -5.010368e-04 -5.244862e-04
## ASV0697     -6.465317e-38 -3.883015e-04 -4.064848e-04 -4.250758e-04
## ASV0785      1.187710e-37  7.181085e-04  7.519560e-04  7.866026e-04
## ASV1967     -1.094681e-37 -6.605854e-04 -6.917785e-04 -7.235550e-04
## ASV0385      1.211612e-38  8.432608e-05  8.844300e-05  9.306609e-05
## ASV0295      2.560088e-39  2.213490e-05  2.330667e-05  2.472936e-05
## ASV0072     -7.811027e-38 -4.676915e-04 -4.896198e-04 -5.119345e-04
## ASV0157     -3.021509e-38 -1.756062e-04 -1.837299e-04 -1.918131e-04
## ASV0501      1.868061e-37  1.168316e-03  1.223802e-03  1.282075e-03
## ASV10729    -2.253751e-37 -1.389910e-03 -1.455499e-03 -1.523919e-03
## ASV1470      1.482080e-37  8.505183e-04  8.903695e-04  9.290718e-04
## ASV0050     -1.794000e-37 -1.087571e-03 -1.138772e-03 -1.191368e-03
## ASV0411     -3.253026e-38 -1.971051e-04 -2.063860e-04 -2.159286e-04
## ASV0549      5.575762e-38  3.440235e-04  3.603932e-04  3.773606e-04
## ASV0184      1.778751e-38  1.081236e-04  1.131730e-04  1.184101e-04
## ASV0705      4.531555e-38  2.785023e-04  2.916326e-04  3.052849e-04
## ASV1715      1.031142e-37  6.305249e-04  6.602539e-04  6.910245e-04
## ASV0603      1.577904e-38  9.837949e-05  1.030120e-04  1.079113e-04
## ASV0826      1.428508e-37  8.629461e-04  9.036000e-04  9.451707e-04
## ASV0034     -5.786920e-38 -3.487990e-04 -3.651179e-04 -3.818697e-04
## ASV0838      8.078048e-38  4.849613e-04  5.072320e-04  5.303597e-04
## ASV0614     -6.495840e-38 -3.960924e-04 -4.147806e-04 -4.340485e-04
## ASV0014     -1.022465e-37 -6.219333e-04 -6.511924e-04 -6.813749e-04
## ASV0585     -8.322572e-39 -5.167446e-05 -5.434074e-05 -5.694127e-05
## ASV0016     -1.072154e-37 -6.523263e-04 -6.829687e-04 -7.146309e-04
## ASV5394     -1.028938e-37 -6.313187e-04 -6.611418e-04 -6.920568e-04
## ASV0666      1.988511e-37  1.196628e-03  1.252489e-03  1.309846e-03
## ASV2085      5.210316e-38  2.873010e-04  3.000506e-04  3.124136e-04
## ASV0003     -7.449963e-38 -4.529316e-04 -4.741635e-04 -4.961272e-04
## ASV0346      1.589392e-38  1.063785e-04  1.116411e-04  1.173141e-04
## ASV0267     -1.158362e-38 -6.419578e-05 -6.680122e-05 -6.955324e-05
## ASV0353      5.635721e-38  3.588322e-04  3.759273e-04  3.941579e-04
## ASV2419      2.054386e-37  1.242573e-03  1.300768e-03  1.360678e-03
## ASV0447      8.167316e-38  5.086960e-04  5.329457e-04  5.582592e-04
## ASV0654      1.379564e-37  8.446563e-04  8.845217e-04  9.257942e-04
## ASV0151      9.844258e-39  6.603616e-05  6.944791e-05  7.299236e-05
## ASV0065     -5.772039e-38 -3.466400e-04 -3.629010e-04 -3.794946e-04
## ASV0527      1.502091e-37  9.154607e-04  9.584388e-04  1.002943e-03
## ASV4055     -3.264825e-38 -2.072086e-04 -2.171002e-04 -2.276120e-04
## ASV0166     -8.182560e-38 -4.782385e-04 -5.004569e-04 -5.226729e-04
## ASV0417     -5.932209e-38 -3.538695e-04 -3.703369e-04 -3.871352e-04
## ASV0078     -4.234571e-38 -2.519293e-04 -2.636742e-04 -2.756061e-04
## ASV0322     -5.471037e-38 -3.094260e-04 -3.237216e-04 -3.375605e-04
## ASV0156     -9.647230e-38 -5.790517e-04 -6.062661e-04 -6.339929e-04
## ASV0648     -2.834217e-37 -1.748618e-03 -1.831199e-03 -1.917327e-03
## ASV0407     -7.646890e-39 -4.937796e-05 -5.168368e-05 -5.421527e-05
## ASV2030     -3.953299e-38 -2.384990e-04 -2.498741e-04 -2.613546e-04
## ASV0300      2.277743e-38  1.459910e-04  1.530074e-04  1.604742e-04
## ASV1150     -2.682781e-39 -1.466506e-05 -1.528155e-05 -1.590095e-05
## ASV0958      7.004943e-38  4.378645e-04  4.587761e-04  4.806539e-04
## ASV0216     -8.478974e-38 -5.119527e-04 -5.357801e-04 -5.604130e-04
## ASV0446      1.201951e-37  7.470616e-04  7.824487e-04  8.195231e-04
## ASV0367     -9.191606e-38 -5.645619e-04 -5.912098e-04 -6.188951e-04
## ASV0200     -5.247794e-38 -3.185394e-04 -3.335727e-04 -3.490065e-04
## ASV0334     -3.506741e-38 -2.019232e-04 -2.110054e-04 -2.201890e-04
## ASV1311      3.554008e-38  2.130824e-04  2.228259e-04  2.329787e-04
## ASV0458      7.729885e-38  4.605129e-04  4.820742e-04  5.038961e-04
## ASV1371      7.512118e-39  4.717749e-05  4.944534e-05  5.181496e-05
## ASV0418      1.893337e-37  1.120701e-03  1.173104e-03  1.225893e-03
## ASV0004      1.804419e-38  1.080705e-04  1.131324e-04  1.182885e-04
## ASV1943      6.429812e-37  3.826408e-03  4.008246e-03  4.189731e-03
## ASV1495     -2.211632e-38 -1.535696e-04 -1.612495e-04 -1.697178e-04
## ASV0901     -1.131054e-37 -6.983704e-04 -7.315018e-04 -7.659517e-04
## ASV0628      5.546521e-38  3.311734e-04  3.464817e-04  3.622035e-04
## ASV0400      2.805425e-38  1.712796e-04  1.792761e-04  1.876060e-04
## ASV0116     -3.205427e-38 -1.969600e-04 -2.063028e-04 -2.159718e-04
## ASV0788      2.271701e-37  1.397929e-03  1.464086e-03  1.532765e-03
## ASV0117      1.927075e-38  1.210921e-04  1.269105e-04  1.329946e-04
## ASV3137     -8.767456e-40 -4.648771e-06 -4.844600e-06 -5.030124e-06
## ASV0001      2.197299e-38  1.307714e-04  1.368337e-04  1.430270e-04
## ASV1651      5.685277e-38  3.369699e-04  3.526195e-04  3.685085e-04
## ASV1692      1.886592e-37  1.164581e-03  1.219828e-03  1.277241e-03
## ASV0660      6.721280e-38  3.967397e-04  4.149136e-04  4.334817e-04
## ASV0508     -4.434416e-40 -5.463456e-06 -5.752443e-06 -6.160323e-06
## ASV1660     -5.284335e-38 -3.327497e-04 -3.487223e-04 -3.654688e-04
## ASV0233      4.099784e-38  2.497985e-04  2.616006e-04  2.737490e-04
## ASV1343     -1.274381e-37 -7.862168e-04 -8.233970e-04 -8.621295e-04
## ASV0209      6.140143e-38  3.679730e-04  3.849784e-04  4.025225e-04
## ASV0193     -8.704938e-38 -5.049013e-04 -5.282168e-04 -5.514636e-04
## ASV0357      1.377412e-38  8.869041e-05  9.314505e-05  9.772540e-05
## ASV0198      4.709804e-38  2.904221e-04  3.040629e-04  3.183433e-04
## ASV0007      2.311821e-38  1.371622e-04  1.435005e-04  1.499733e-04
## ASV1772     -3.325135e-38 -1.990915e-04 -2.083638e-04 -2.178471e-04
## ASV0009      2.170475e-38  1.284295e-04  1.343440e-04  1.403853e-04
## ASV0006     -1.820060e-39 -1.376054e-05 -1.450942e-05 -1.531924e-05
## ASV0011     -4.025319e-38 -2.479354e-04 -2.596401e-04 -2.718315e-04
## ASV0015      1.405308e-38  8.346896e-05  8.735742e-05  9.130113e-05
## ASV0017      1.527496e-38  9.069456e-05  9.490464e-05  9.918765e-05
## ASV0235     -4.894084e-38 -3.060705e-04 -3.205438e-04 -3.358212e-04
## ASV0382      1.920122e-38  1.247139e-04  1.307762e-04  1.372309e-04
## ASV2357      1.617275e-37  9.950562e-04  1.041932e-03  1.090803e-03
## ASV0567     -4.374086e-38 -2.654597e-04 -2.779285e-04 -2.907857e-04
## ASV0165      2.807167e-38  1.738140e-04  1.820104e-04  1.905996e-04
## ASV0005      3.542869e-38  2.141538e-04  2.241721e-04  2.344916e-04
## ASV0384     -3.520415e-39 -1.619466e-05 -1.681119e-05 -1.731413e-05
## ASV0002      6.019539e-39  3.656601e-05  3.830091e-05  4.007436e-05
## ASV3017      2.296311e-37  1.382574e-03  1.446859e-03  1.513177e-03
## ASV0091     -1.735548e-40 -6.336404e-07 -6.599795e-07 -6.706379e-07
## ASV0186     -9.091321e-38 -5.564020e-04 -5.826031e-04 -6.097748e-04
## ASV0370      2.619667e-38  1.626633e-04  1.701695e-04  1.782241e-04
## ASV0018      4.825078e-38  2.920391e-04  3.056994e-04  3.197917e-04
## ASV1377      7.336761e-37  4.435357e-03  4.642486e-03  4.856149e-03
## ASV0019      5.050491e-38  3.058255e-04  3.201086e-04  3.348717e-04
## ASV0023     -1.398700e-38 -8.854112e-05 -9.285579e-05 -9.733671e-05
## ASV2194      5.683899e-38  3.433626e-04  3.596663e-04  3.762360e-04
## ASV1155      1.068389e-37  6.548323e-04  6.869331e-04  7.190157e-04
## ASV0510     -9.113869e-38 -5.206763e-04 -5.437484e-04 -5.672566e-04
## ASV2371     -1.257836e-37 -7.503614e-04 -7.857251e-04 -8.213613e-04
## ASV0024     -1.915673e-38 -1.202644e-04 -1.260652e-04 -1.320990e-04
## ASV2452      1.456958e-37  8.677003e-04  9.076436e-04  9.487483e-04
## ASV2332     -1.617521e-37 -9.890974e-04 -1.035578e-03 -1.083697e-03
## ASV2591      9.996402e-38  6.448841e-04  6.753297e-04  7.085383e-04
## ASV0521      7.497434e-38  4.638249e-04  4.857650e-04  5.086727e-04
## ASV5542      6.541575e-38  4.056084e-04  4.243714e-04  4.444215e-04
## ASV0336     -2.681139e-38 -1.544965e-04 -1.617954e-04 -1.688877e-04
## ASV10102     1.374001e-37  8.510964e-04  8.911619e-04  9.332484e-04
## ASV16823    -2.104537e-37 -1.253189e-03 -1.312226e-03 -1.371632e-03
## ASV3104      1.161414e-36  6.915872e-03  7.241139e-03  7.568949e-03
## ASV0781      1.274481e-37  7.827830e-04  8.192735e-04  8.576178e-04
## ASV10899     7.388709e-38  4.765424e-04  4.994311e-04  5.239886e-04
## ASV11222    -3.676031e-37 -2.188967e-03 -2.291812e-03 -2.395566e-03
## ASV11327    -3.306391e-37 -1.968857e-03 -2.061209e-03 -2.154521e-03
## ASV12458    -3.676031e-37 -2.188966e-03 -2.291474e-03 -2.395208e-03
## ASV1636      2.704271e-38  1.703174e-04  1.781024e-04  1.866601e-04
## ASV1890     -2.399684e-37 -1.421978e-03 -1.488489e-03 -1.555504e-03
## ASV2898      2.747572e-37  1.662717e-03  1.740116e-03  1.820278e-03
## ASV8328     -7.930990e-40  3.779756e-05  4.046857e-05  4.457618e-05
## ASV0709     -3.031337e-37 -1.841324e-03 -1.926845e-03 -2.015969e-03
## ASV0856      2.031112e-37  1.264499e-03  1.324413e-03  1.387289e-03
## ASV0909     -2.700791e-38 -1.245277e-04 -1.287953e-04 -1.326907e-04
## ASV0937     -1.737019e-37 -1.064047e-03 -1.114541e-03 -1.166592e-03
## ASV11390    -5.207269e-37 -3.100773e-03 -3.245646e-03 -3.392578e-03
## ASV11966     1.134161e-37  7.148652e-04  7.488885e-04  7.848926e-04
## ASV12990     7.930626e-38  4.868453e-04  5.090178e-04  5.328171e-04
## ASV14797     1.386496e-37  8.363583e-04  8.748448e-04  9.150000e-04
## ASV14904    -7.391907e-37 -4.401659e-03 -4.607207e-03 -4.815786e-03
## ASV15304     5.730069e-38  3.727405e-04  3.906452e-04  4.100041e-04
## ASV16696    -2.614804e-37 -1.557037e-03 -1.629650e-03 -1.703428e-03
## ASV1690      4.124258e-37  2.567047e-03  2.689161e-03  2.816784e-03
## ASV2029      3.095950e-37  1.876496e-03  1.964054e-03  2.054697e-03
## ASV2834      4.893075e-37  2.999998e-03  3.141355e-03  3.288132e-03
## ASV4003      2.818388e-37  1.773739e-03  1.858366e-03  1.947600e-03
## ASV4064      1.855609e-37  1.131598e-03  1.184883e-03  1.239942e-03
## ASV4294      9.559295e-38  6.170254e-04  6.467226e-04  6.785545e-04
## ASV4609      5.935566e-38  3.537827e-04  3.691924e-04  3.859358e-04
## ASV6283     -2.446292e-37 -1.456693e-03 -1.524661e-03 -1.593692e-03
## ASV6491     -3.488537e-37 -2.077319e-03 -2.174085e-03 -2.272517e-03
## ASV7453      1.430583e-37  9.047425e-04  9.479659e-04  9.936696e-04
## ASV7959      3.215015e-38  2.230256e-04  2.340121e-04  2.462802e-04
## ASV8219      3.595766e-36  2.141170e-02  2.240804e-02  2.342258e-02
## ASV8547     -3.128805e-37 -1.863109e-03 -1.949662e-03 -2.037930e-03
## ASV9319      1.267838e-37  7.867417e-04  8.237555e-04  8.627271e-04
## ASV9382     -6.035180e-37 -3.593768e-03 -3.760550e-03 -3.930804e-03
## ASV11516    -4.070196e-37 -2.423678e-03 -2.535974e-03 -2.650782e-03
## ASV14377    -2.954957e-37 -1.759587e-03 -1.840980e-03 -1.924320e-03
## ASV1867      2.355221e-37  1.450559e-03  1.518951e-03  1.590270e-03
## ASV1895      4.075438e-38  2.494681e-04  2.609485e-04  2.730756e-04
## ASV3168      1.342523e-37  8.089223e-04  8.462066e-04  8.849882e-04
## ASV4449      8.479981e-37  5.157249e-03  5.399111e-03  5.649269e-03
## ASV6596      1.511414e-37  9.585873e-04  1.004690e-03  1.053311e-03
## ASV7492     -4.627085e-38 -2.521238e-04 -2.629425e-04 -2.735995e-04
## ASV9854     -7.833338e-38 -4.611967e-04 -4.825205e-04 -5.040938e-04
## ASV6296      6.632255e-36  3.949307e-02  4.131539e-02  4.318567e-02
## ASV4201      5.879822e-38  3.967408e-04  4.167298e-04  4.380897e-04
## ASV0552      1.527666e-37  9.423474e-04  9.868188e-04  1.033217e-03
## ASV3671     -8.300008e-38 -4.935301e-04 -5.163517e-04 -5.397101e-04
## ASV3529     -4.642867e-38 -2.583725e-04 -2.695549e-04 -2.807995e-04
## ASV1060      5.877354e-38  3.627275e-04  3.799639e-04  3.978473e-04
## ASV0239     -6.645116e-38 -3.928176e-04 -4.107908e-04 -4.292203e-04
## ASV5711     -2.515455e-37 -1.517585e-03 -1.588186e-03 -1.661133e-03
## ASV4152     -4.046551e-37 -2.458585e-03 -2.573714e-03 -2.692817e-03
## ASV1461      1.917535e-37  1.146128e-03  1.198696e-03  1.253154e-03
## ASV2877      9.931301e-38  5.929329e-04  6.203455e-04  6.484990e-04
## ASV0012      1.314663e-38  8.053713e-05  8.435571e-05  8.829504e-05
## ASV9823      3.793949e-38  2.014065e-04  2.105292e-04  2.188516e-04
## ASV0008      1.414635e-38  8.633042e-05  9.040265e-05  9.460718e-05
## ASV7832     -2.512106e-37 -1.533585e-03 -1.605333e-03 -1.680001e-03
## ASV1915     -7.525957e-39 -3.772769e-05 -3.916131e-05 -4.056075e-05
## ASV0055      2.450120e-39  1.118357e-05  1.161443e-05  1.195625e-05
## ASV0032      2.728753e-38  1.642429e-04  1.717981e-04  1.796663e-04
## ASV2977     -3.561796e-37 -2.155099e-03 -2.255660e-03 -2.359556e-03
## ASV0466      2.733792e-37  1.624689e-03  1.699408e-03  1.776144e-03
## ASV3866      1.760754e-37  1.084758e-03  1.135957e-03  1.189308e-03
## ASV0040      4.699517e-38  2.882762e-04  3.018783e-04  3.159927e-04
## ASV0496     -1.288536e-38 -9.531055e-05 -1.003390e-04 -1.058770e-04
## ASV0052      6.057237e-38  3.693449e-04  3.866050e-04  4.045632e-04
## ASV3828     -3.751563e-37 -2.278264e-03 -2.384331e-03 -2.494623e-03
## ASV1930      1.169582e-37  7.142018e-04  7.475659e-04  7.823317e-04
## ASV2126      1.456463e-37  8.835387e-04  9.247619e-04  9.674818e-04
## ASV0793      1.620282e-37  9.960381e-04  1.043321e-03  1.092210e-03
## ASV0299     -1.311933e-38 -8.004298e-05 -8.367978e-05 -8.756752e-05
## ASV0208      1.147054e-37  7.102073e-04  7.437454e-04  7.788440e-04
## ASV0511     -6.989265e-38 -4.165831e-04 -4.355324e-04 -4.552579e-04
## ASV1123     -2.239972e-37 -1.327560e-03 -1.388324e-03 -1.450823e-03
## ASV0099     -7.844886e-39 -4.310869e-05 -4.505846e-05 -4.691033e-05
## ASV0752     -6.224289e-38 -3.927402e-04 -4.114939e-04 -4.313011e-04
## ASV0883      8.109358e-38  5.028546e-04  5.268019e-04  5.517099e-04
## ASV0683      1.690633e-37  1.048815e-03  1.098616e-03  1.150588e-03
## ASV4117     -4.299106e-37 -2.609087e-03 -2.730973e-03 -2.857206e-03
## ASV2172      3.570402e-38  2.129440e-04  2.227801e-04  2.328863e-04
## ASV0330     -4.963671e-38 -3.021133e-04 -3.163456e-04 -3.310240e-04
## ASV0728      2.603246e-37  1.590600e-03  1.665409e-03  1.742945e-03
## ASV0499      6.170363e-38  3.826900e-04  4.008564e-04  4.198182e-04
## ASV0120     -1.087437e-37 -6.633760e-04 -6.944264e-04 -7.266936e-04
## ASV1446      1.140615e-37  6.670806e-04  6.973672e-04  7.282643e-04
## ASV17171    -1.941736e-37 -1.183941e-03 -1.239357e-03 -1.296938e-03
## ASV0533      1.709255e-38  1.077949e-04  1.129730e-04  1.184080e-04
## ASV2495     -6.593953e-38 -4.180520e-04 -4.381783e-04 -4.593853e-04
## ASV5582      9.415903e-38  5.429951e-04  5.673676e-04  5.921095e-04
## ASV1488      6.620589e-38  4.358554e-04  4.564507e-04  4.792157e-04
## ASV0682      4.548255e-38  2.842487e-04  2.977569e-04  3.119511e-04
## ASV0068     -5.092313e-38 -3.125196e-04 -3.272996e-04 -3.426047e-04
## ASV1987     -1.849195e-37 -1.155610e-03 -1.210727e-03 -1.268444e-03
## ASV0035     -5.588354e-39 -4.207597e-05 -4.441119e-05 -4.690224e-05
## ASV7192     -1.485948e-37 -8.925035e-04 -9.338268e-04 -9.764960e-04
## ASV0873      9.174617e-38  4.349824e-04  4.498018e-04  4.642227e-04
## ASV4749      7.302796e-39  1.710469e-05  1.663252e-05  1.594843e-05
## ASV2174      1.504672e-37  8.698641e-04  9.097474e-04  9.496673e-04
## ASV1476     -8.843946e-38 -5.434809e-04 -5.692144e-04 -5.958938e-04
## ASV0740     -3.028369e-37 -1.870471e-03 -1.959218e-03 -2.051488e-03
## ASV0170     -3.959415e-38 -2.427122e-04 -2.541011e-04 -2.659718e-04
## ASV2466     -2.982967e-37 -1.822318e-03 -1.907737e-03 -1.996549e-03
## ASV1709      1.284559e-37  7.692421e-04  8.046575e-04  8.413113e-04
## ASV6170     -7.223576e-37 -4.327063e-03 -4.531277e-03 -4.738146e-03
## ASV3673      2.191351e-37  1.300403e-03  1.361937e-03  1.423507e-03
## ASV1745      4.254043e-38  2.194787e-04  2.296968e-04  2.384253e-04
## ASV0380     -1.985728e-37 -1.089039e-03 -1.139624e-03 -1.186566e-03
## ASV0426      4.129004e-39  4.788244e-05  5.000192e-05  5.344979e-05
## ASV0202     -2.116519e-39 -4.753710e-07  1.808413e-08  6.686850e-07
## ASV6350     -2.479734e-37 -1.445049e-03 -1.513208e-03 -1.580299e-03
## ASV0713     -9.664623e-38 -5.935452e-04 -6.215544e-04 -6.506593e-04
## ASV1822      4.759007e-39  4.271597e-05  4.452426e-05  4.725254e-05
## ASV4569      3.078668e-37  1.834215e-03  1.919831e-03  2.006927e-03
## ASV0030     -2.585480e-38 -1.607125e-04 -1.683411e-04 -1.763125e-04
## ASV0331      1.021185e-37  6.363262e-04  6.664857e-04  6.981494e-04
## ASV2981      2.951722e-37  1.826421e-03  1.912295e-03  2.002444e-03
## ASV0828     -2.090453e-38 -2.355712e-04 -2.475516e-04 -2.644874e-04
## ASV2440      2.583330e-37  1.593948e-03  1.669136e-03  1.747629e-03
## ASV3006     -1.603036e-36 -8.956017e-03 -9.376792e-03 -9.772801e-03
## ASV3875      1.490529e-35  8.327445e-02  8.718054e-02  9.086278e-02
## ASV4511      1.445779e-37  8.954557e-04  9.380166e-04  9.823290e-04
## ASV4700     -5.895173e-37 -3.293577e-03 -3.447812e-03 -3.593451e-03
## ASV5804     -1.384475e-35 -7.734926e-02 -8.096561e-02 -8.438597e-02
## ASV6826      2.060156e-37  1.283910e-03  1.344766e-03  1.408681e-03
## ASV7280      1.873374e-37  1.188132e-03  1.244097e-03  1.304137e-03
## ASV7535     -5.895173e-37 -3.293573e-03 -3.447403e-03 -3.593058e-03
## ASV0651     -1.091351e-37 -6.533693e-04 -6.832769e-04 -7.143533e-04
## ASV0913      2.359889e-37  1.461044e-03  1.530233e-03  1.602495e-03
## ASV10832    -6.290752e-37 -3.514578e-03 -3.678471e-03 -3.833902e-03
## ASV1117     -5.679100e-37 -3.383887e-03 -3.542450e-03 -3.703205e-03
## ASV11329     7.265263e-38  4.923408e-04  5.162496e-04  5.427114e-04
## ASV13209    -2.571526e-39  5.421244e-05  5.703754e-05  6.303948e-05
## ASV1345      1.210874e-37  7.732460e-04  8.100197e-04  8.492832e-04
## ASV1719     -8.859424e-37 -4.949663e-03 -5.179960e-03 -5.398883e-03
## ASV1886      1.506468e-37  9.030522e-04  9.453374e-04  9.885414e-04
## ASV2158     -2.573313e-38 -7.835439e-05 -8.140827e-05 -8.145152e-05
## ASV2189      2.488408e-37  1.512563e-03  1.583690e-03  1.657068e-03
## ASV2257      2.615986e-37  1.573375e-03  1.647930e-03  1.723561e-03
## ASV2283      6.863995e-37  3.834835e-03  4.012645e-03  4.182250e-03
## ASV2328      4.228965e-37  2.362673e-03  2.472046e-03  2.576541e-03
## ASV2434     -3.743014e-37 -2.197603e-03 -2.300617e-03 -2.403533e-03
## ASV2648      7.720427e-37  4.313308e-03  4.512287e-03  4.703036e-03
## ASV2698      6.702958e-37  4.108988e-03  4.302850e-03  4.504053e-03
## ASV2775      2.212879e-37  1.303667e-03  1.363750e-03  1.424840e-03
## ASV3171      3.722075e-37  2.079476e-03  2.175090e-03  2.267039e-03
## ASV3227      3.432870e-37  2.013560e-03  2.105956e-03  2.199827e-03
## ASV3397      1.461054e-37  9.258490e-04  9.701596e-04  1.016831e-03
## ASV3444      4.947089e-37  2.886485e-03  3.020937e-03  3.155169e-03
## ASV3556      1.548396e-36  8.650683e-03  9.046894e-03  9.429361e-03
## ASV3606     -3.639624e-36 -2.033409e-02 -2.126390e-02 -2.216291e-02
## ASV4190      4.338340e-37  2.643988e-03  2.768372e-03  2.897041e-03
## ASV4197      2.919344e-37  1.706539e-03  1.785819e-03  1.865227e-03
## ASV4722      4.236371e-37  2.549755e-03  2.668884e-03  2.791281e-03
## ASV4765      2.112503e-37  1.325927e-03  1.387284e-03  1.453333e-03
## ASV4809      9.151299e-37  5.112702e-03  5.345649e-03  5.571663e-03
## ASV4846      3.716586e-37  2.284232e-03  2.391018e-03  2.502922e-03
## ASV4903     -3.711158e-38 -1.451727e-04 -1.510288e-04 -1.541946e-04
## ASV4944     -3.748268e-37 -2.094102e-03 -2.189365e-03 -2.281942e-03
## ASV5151      1.359609e-37  4.499084e-04  4.640374e-04  4.672014e-04
## ASV5413     -8.246019e-37 -4.606926e-03 -4.816142e-03 -5.019817e-03
## ASV5537     -8.859424e-37 -4.949623e-03 -5.174039e-03 -5.392858e-03
## ASV5688      7.447089e-37  4.160571e-03  4.348906e-03  4.532835e-03
## ASV5752      1.825374e-37  1.157489e-03  1.212991e-03  1.271382e-03
## ASV6122     -9.540121e-37 -5.329911e-03 -5.570886e-03 -5.806509e-03
## ASV6135      5.008681e-37  2.798267e-03  2.924577e-03  3.048277e-03
## ASV6188     -3.041284e-36 -1.699114e-02 -1.775686e-02 -1.850794e-02
## ASV6216      6.352992e-37  3.746379e-03  3.919583e-03  4.095595e-03
## ASV6242      5.008681e-37  2.798263e-03  2.923996e-03  3.047673e-03
## ASV6383      3.131950e-36  1.749765e-02  1.828259e-02  1.905591e-02
## ASV6781      6.970657e-37  3.894381e-03  4.068800e-03  4.240905e-03
## ASV6799     -1.323819e-36 -7.395934e-03 -7.726643e-03 -8.053475e-03
## ASV7374     -2.809296e-37 -1.569501e-03 -1.639568e-03 -1.708921e-03
## ASV7539     -3.748268e-37 -2.094086e-03 -2.187420e-03 -2.279949e-03
## ASV8591     -9.540121e-37 -5.329880e-03 -5.567053e-03 -5.802541e-03
## ASV8637      4.188427e-36  2.339992e-02  2.443950e-02  2.547330e-02
## ASV12796    -5.527703e-37 -3.088216e-03 -3.225194e-03 -3.361621e-03
## ASV1934      2.493290e-37  1.527348e-03  1.599124e-03  1.673810e-03
## ASV22549     1.066740e-38  1.178962e-04  1.249630e-04  1.332907e-04
## ASV29857    -2.144237e-37 -1.197941e-03 -1.250994e-03 -1.303913e-03
## ASV3215      2.601109e-37  1.612452e-03  1.688994e-03  1.768889e-03
## ASV3236     -5.527703e-37 -3.088212e-03 -3.224738e-03 -3.361148e-03
## ASV3954     -5.527703e-37 -3.088210e-03 -3.224515e-03 -3.360915e-03
## ASV4850      3.705731e-37  2.070312e-03  2.161542e-03  2.252976e-03
## ASV5225      3.578683e-36  1.999331e-02  2.087291e-02  2.175584e-02
## ASV5532     -1.911598e-37 -1.067967e-03 -1.114876e-03 -1.162035e-03
## ASV7258      1.104303e-37  7.693184e-04  8.085581e-04  8.508856e-04
## ASV9474     -7.248422e-38 -3.513025e-04 -3.648849e-04 -3.775074e-04
## ASV11857    -7.182966e-37 -4.012957e-03 -4.188948e-03 -4.366146e-03
## ASV1202     -4.561803e-37 -2.548572e-03 -2.660161e-03 -2.772687e-03
## ASV14742     9.868216e-38  6.509266e-04  6.830413e-04  7.172284e-04
## ASV16652     7.877055e-38  5.079298e-04  5.329476e-04  5.589432e-04
## ASV2019      3.105732e-37  1.837442e-03  1.921643e-03  2.008232e-03
## ASV2410     -6.630715e-37 -4.024512e-03 -4.212394e-03 -4.407508e-03
## ASV2718      1.573889e-37  9.839136e-04  1.030705e-03  1.079773e-03
## ASV2738      5.107838e-37  3.018564e-03  3.156476e-03  3.298379e-03
## ASV2876      3.317386e-37  1.853343e-03  1.934217e-03  2.016030e-03
## ASV3177      4.445615e-37  2.483656e-03  2.591859e-03  2.701486e-03
## ASV4367      5.493700e-37  3.069194e-03  3.202690e-03  3.338149e-03
## ASV4635      1.325629e-37  8.859676e-04  9.301300e-04  9.770320e-04
## ASV4896      8.582928e-38  6.260056e-04  6.590226e-04  6.947172e-04
## ASV4907      1.158831e-37  7.562613e-04  7.936051e-04  8.329285e-04
## ASV5230     -4.276572e-37 -2.389212e-03 -2.493168e-03 -2.598628e-03
## ASV6509     -4.561803e-37 -2.548562e-03 -2.659272e-03 -2.771755e-03
## ASV7376     -3.263923e-37 -1.823468e-03 -1.902552e-03 -1.983024e-03
## ASV8163     -4.863810e-37 -2.717282e-03 -2.834940e-03 -2.954845e-03
## ASV8195     -4.276572e-37 -2.389206e-03 -2.492491e-03 -2.597907e-03
## ASV8923      1.072871e-37  6.968094e-04  7.310370e-04  7.670486e-04
## ASV9666     -2.509044e-37 -1.316698e-03 -1.369980e-03 -1.423408e-03
## ASV1482      1.922554e-37  1.198570e-03  1.255712e-03  1.315352e-03
## ASV2726      1.758705e-37  1.100337e-03  1.152980e-03  1.207912e-03
## ASV3281     -1.781960e-36 -9.955316e-03 -1.038511e-02 -1.082434e-02
## ASV4235     -1.781960e-36 -9.955310e-03 -1.038441e-02 -1.082359e-02
## ASV4808      3.368542e-37  1.987811e-03  2.078021e-03  2.171456e-03
## ASV4861     -8.319372e-37 -4.880285e-03 -5.100198e-03 -5.328188e-03
## ASV5276      4.807266e-37  2.837489e-03  2.965989e-03  3.099291e-03
## ASV5837      1.458067e-37  8.979081e-04  9.402433e-04  9.844422e-04
## ASV7098      2.111962e-37  1.294560e-03  1.355325e-03  1.418722e-03
## ASV8451     -3.033825e-37 -1.694911e-03 -1.767441e-03 -1.842167e-03
## ASV8694     -1.781960e-36 -9.955289e-03 -1.038062e-02 -1.081947e-02
## ASV0905     -6.407135e-38 -4.099201e-04 -4.298421e-04 -4.506166e-04
## ASV2900      3.940290e-37  2.268400e-03  2.368293e-03  2.471927e-03
## ASV3963     -4.071805e-37 -2.319272e-03 -2.420180e-03 -2.524845e-03
## ASV0041     -6.218917e-38 -3.869361e-04 -4.054036e-04 -4.246220e-04
## ASV1865      1.779340e-37  1.129992e-03  1.184791e-03  1.242046e-03
## ASV1140      1.014314e-37  6.390151e-04  6.698800e-04  7.019433e-04
## ASV1179      1.094094e-37  6.710392e-04  7.026142e-04  7.354436e-04
## ASV0279      1.710284e-37  1.031533e-03  1.079367e-03  1.128984e-03
## ASV0043     -2.664300e-38 -1.726818e-04 -1.812040e-04 -1.901670e-04
## ASV2097     -1.072570e-37 -6.275482e-04 -6.555301e-04 -6.847589e-04
## ASV0309     -2.061420e-38 -1.227139e-04 -1.284753e-04 -1.343015e-04
## ASV0607      2.591258e-37  1.594127e-03  1.668959e-03  1.747208e-03
## ASV0025     -7.143956e-38 -4.418604e-04 -4.627972e-04 -4.846069e-04
## ASV2284     -3.103134e-37 -1.794986e-03 -1.878536e-03 -1.961163e-03
## ASV0556      6.882204e-38  4.400105e-04  4.609413e-04  4.833630e-04
## ASV5040     -1.489317e-37 -1.324548e-03 -1.404545e-03 -1.490064e-03
## ASV2924     -1.017458e-36 -5.817674e-03 -6.072351e-03 -6.335982e-03
## ASV1331      2.332497e-37  1.421257e-03  1.487849e-03  1.556948e-03
## ASV0506     -1.122398e-37 -6.443734e-04 -6.739280e-04 -7.032467e-04
## ASV1514      3.524163e-37  2.151919e-03  2.252799e-03  2.357583e-03
## ASV2144      3.377438e-37  2.055714e-03  2.151825e-03  2.251637e-03
## ASV2265      2.209608e-37  1.349445e-03  1.412847e-03  1.478602e-03
## ASV5156      1.976386e-37  1.100442e-03  1.150080e-03  1.198395e-03
## ASV5534      6.386076e-38  3.434711e-04  3.585794e-04  3.729732e-04
## ASV5747      1.966771e-52 -2.222768e-04 -2.369421e-04 -2.588539e-04
## ASV6657      1.810529e-37  1.070558e-03  1.120301e-03  1.170711e-03
## ASV0658     -1.396279e-37 -8.083678e-04 -8.454074e-04 -8.825547e-04
## ASV0716      2.382154e-37  1.423678e-03  1.489188e-03  1.556865e-03
## ASV1657      4.796871e-37  2.795528e-03  2.922851e-03  3.052190e-03
## ASV1885      4.282908e-37  2.414702e-03  2.522725e-03  2.630193e-03
## ASV2333      2.031212e-37  1.226169e-03  1.283183e-03  1.342174e-03
## ASV3375      1.663026e-37  9.733196e-04  1.017973e-03  1.063283e-03
## ASV4317      1.382353e-37  8.449170e-04  8.848749e-04  9.261616e-04
## ASV9599     -4.454021e-53 -9.293128e-05 -9.952581e-05 -1.087121e-04
## ASV0175     -2.226034e-37 -1.337292e-03 -1.398813e-03 -1.462725e-03
## ASV1032      9.934150e-38  5.775129e-04  6.037152e-04  6.303630e-04
## ASV1235      1.902673e-37  1.067085e-03  1.114083e-03  1.161175e-03
## ASV1262      2.263316e-37  1.369226e-03  1.432724e-03  1.498720e-03
## ASV1320      1.195597e-37  7.680913e-04  8.052841e-04  8.446751e-04
## ASV13797     1.340585e-37  7.991933e-04  8.361789e-04  8.741502e-04
## ASV1491      1.695400e-37  1.109538e-03  1.163787e-03  1.221535e-03
## ASV15014     7.449680e-53 -7.216620e-05 -7.741628e-05 -8.455327e-05
## ASV1510      2.466246e-37  1.551977e-03  1.625857e-03  1.703718e-03
## ASV1551      8.703714e-37  5.329481e-03  5.579247e-03  5.839570e-03
## ASV1919      5.904668e-38  5.179888e-04  5.462545e-04  5.793504e-04
## ASV2114      1.710338e-37  1.003418e-03  1.049486e-03  1.096363e-03
## ASV21486     5.488312e-53 -6.202729e-05 -6.650018e-05 -7.262408e-05
## ASV2448      1.724039e-37  1.028314e-03  1.075772e-03  1.124616e-03
## ASV2589      3.368275e-37  1.964065e-03  2.053844e-03  2.144884e-03
## ASV2608      2.164775e-37  1.298232e-03  1.358538e-03  1.420601e-03
## ASV2786      4.264204e-37  2.584720e-03  2.705603e-03  2.830745e-03
## ASV2827      1.541384e-37  9.212053e-04  9.638701e-04  1.007710e-03
## ASV2872      6.812204e-37  4.024799e-03  4.209535e-03  4.398559e-03
## ASV3125      1.340457e-37  7.880010e-04  8.239311e-04  8.607577e-04
## ASV3247      2.912571e-37  1.723231e-03  1.802035e-03  1.883118e-03
## ASV3451      1.692142e-52 -1.912416e-04 -2.060923e-04 -2.250472e-04
## ASV3465      1.953441e-38  6.223441e-05  6.356612e-05  6.371453e-05
## ASV3809      3.951174e-37  2.326756e-03  2.432502e-03  2.541394e-03
## ASV4006      1.905472e-37  1.130198e-03  1.181825e-03  1.235122e-03
## ASV4046      2.808132e-37  1.661941e-03  1.737674e-03  1.815901e-03
## ASV4938      4.284200e-38  1.618752e-04  1.660738e-04  1.689125e-04
## ASV5435      4.537792e-52 -3.239063e-04 -3.498005e-04 -3.819375e-04
## ASV5605      1.749850e-37  9.776030e-04  1.020602e-03  1.063590e-03
## ASV5635      1.115075e-52 -1.080203e-04 -1.166963e-04 -1.274121e-04
## ASV5743      1.322655e-37  7.889538e-04  8.252882e-04  8.627714e-04
## ASV6627      1.486809e-52 -1.120244e-04 -1.211270e-04 -1.322455e-04
## ASV6785     -1.025443e-51 -1.247289e-04 -1.348470e-04 -1.472217e-04
## ASV7368      1.590047e-37  9.698073e-04  1.015158e-03  1.062375e-03
## ASV9118      6.479953e-38  3.614582e-04  3.772073e-04  3.930973e-04
## ASV9135      1.239138e-37  6.766330e-04  7.056516e-04  7.345601e-04
## ASV9435      1.419904e-37  8.074158e-04  8.430300e-04  8.792757e-04
## ASV9671      2.296261e-52 -1.597049e-04 -1.729646e-04 -1.888257e-04
## ASV0387     -2.396949e-37 -1.401696e-03 -1.465105e-03 -1.530175e-03
## ASV0454     -3.788763e-37 -2.241317e-03 -2.343685e-03 -2.449090e-03
## ASV0751     -1.136153e-37 -6.497461e-04 -6.785148e-04 -7.078956e-04
## ASV1081      2.209171e-37  1.344647e-03  1.407501e-03  1.472707e-03
## ASV1332      4.005702e-37  2.404173e-03  2.515074e-03  2.629893e-03
## ASV2659      4.328537e-37  2.645658e-03  2.769190e-03  2.897995e-03
## ASV2979      2.026173e-37  1.192464e-03  1.246374e-03  1.302088e-03
## ASV4184      3.034014e-37  1.728930e-03  1.804911e-03  1.882716e-03
## ASV6198      9.400632e-38  5.497335e-04  5.745776e-04  6.001656e-04
## ASV7454      9.997174e-38  5.866959e-04  6.132029e-04  6.405287e-04
## ASV8198      9.608593e-38  5.177724e-04  5.392087e-04  5.608770e-04
## ASV0855      2.377581e-37  1.446368e-03  1.513758e-03  1.583910e-03
## ASV10092     1.137084e-37  6.681748e-04  6.984176e-04  7.296336e-04
## ASV1532      2.065198e-37  1.281133e-03  1.341815e-03  1.405287e-03
## ASV2553      3.782792e-37  2.303939e-03  2.411423e-03  2.523324e-03
## ASV2741      5.020895e-37  3.129358e-03  3.278619e-03  3.434315e-03
## ASV4095      2.887305e-37  1.853595e-03  1.944322e-03  2.039136e-03
## ASV5295      1.190888e-37  6.828938e-04  7.129995e-04  7.439631e-04
## ASV5787      7.477636e-53 -6.542858e-05 -7.115449e-05 -7.767219e-05
## ASV9455      1.517897e-37  9.007025e-04  9.416044e-04  9.841403e-04
## ASV10879     1.366029e-37  8.196713e-04  8.573776e-04  8.965877e-04
## ASV3997      1.644371e-37  1.042208e-03  1.092377e-03  1.145013e-03
## ASV6760      6.602837e-38  3.276237e-04  3.398078e-04  3.518857e-04
## ASV6990      1.453009e-37  8.510259e-04  8.892470e-04  9.288543e-04
## ASV9560      9.579176e-38  5.474192e-04  5.713474e-04  5.961063e-04
## ASV0220     -2.090928e-38 -1.263662e-04 -1.321837e-04 -1.382682e-04
## ASV2518      8.604487e-38  5.247943e-04  5.493035e-04  5.748263e-04
## ASV3615      2.213546e-37  1.331536e-03  1.392803e-03  1.456597e-03
## ASV0075     -3.347411e-40 -3.743834e-06 -4.017609e-06 -4.286060e-06
## ASV8070      1.669427e-38  7.344531e-05  7.562886e-05  7.774005e-05
## ASV1658      9.079091e-38  5.336328e-04  5.577248e-04  5.826513e-04
## ASV0773      1.647593e-37  9.786861e-04  1.023272e-03  1.069516e-03
## ASV0799      2.020012e-38  1.131643e-04  1.177596e-04  1.226898e-04
## ASV1839     -1.122440e-37 -6.740121e-04 -7.052346e-04 -7.374407e-04
## ASV0265      1.240564e-37  7.752919e-04  8.123111e-04  8.510038e-04
## ASV3741      4.937605e-38  2.876083e-04  3.005813e-04  3.138319e-04
## ASV0847      1.760188e-37  1.074585e-03  1.124981e-03  1.177311e-03
## ASV1026      2.340234e-37  1.415798e-03  1.481386e-03  1.549603e-03
## ASV1222     -7.229859e-38 -3.947568e-04 -4.110620e-04 -4.279072e-04
## ASV0729     -3.645871e-39 -2.259586e-05 -2.365053e-05 -2.476895e-05
## ASV0143     -6.090511e-38 -3.603213e-04 -3.766392e-04 -3.935822e-04
## ASV1328      2.505670e-38  1.678796e-04  1.767561e-04  1.857644e-04
## ASV9078     -5.193869e-38 -3.714664e-04 -3.912325e-04 -4.121331e-04
## ASV0027     -6.747669e-38 -4.168501e-04 -4.365371e-04 -4.570802e-04
## ASV0546     -8.435156e-38 -4.937667e-04 -5.159390e-04 -5.389013e-04
## ASV1136      1.939997e-37  1.176770e-03  1.231369e-03  1.288286e-03
## ASV3081      1.013115e-37  6.167467e-04  6.454976e-04  6.754820e-04
## ASV0531      2.614338e-38  1.770262e-04  1.861597e-04  1.956989e-04
## ASV2525      1.557502e-37  9.270206e-04  9.690000e-04  1.012874e-03
## ASV1083     -3.479550e-38 -1.914853e-04 -1.994878e-04 -2.077402e-04
## ASV0424     -2.109046e-38 -1.304192e-04 -1.365701e-04 -1.430055e-04
## ASV0644      1.703669e-53  4.590892e-05  4.997082e-05  5.454734e-05
## ASV6007      3.475206e-54 -4.563293e-05 -4.983262e-05 -5.440683e-05
## ASV0564      6.878421e-38  4.311551e-04  4.518177e-04  4.733839e-04
## ASV1938      2.419944e-37  1.396209e-03  1.457942e-03  1.521687e-03
## ASV6516     -3.483260e-37 -2.131790e-03 -2.231590e-03 -2.335677e-03
## ASV0503     -1.495687e-37 -8.682040e-04 -9.066508e-04 -9.465631e-04
## ASV6913     -7.124961e-37 -4.277927e-03 -4.474243e-03 -4.679082e-03
## ASV0164     -8.536975e-38 -5.265638e-04 -5.513605e-04 -5.772866e-04
## ASV1576      2.494705e-37  1.507118e-03  1.576716e-03  1.649342e-03
## ASV1725      1.148624e-37  7.312357e-04  7.666420e-04  8.037358e-04
## ASV4501      7.395110e-38  4.129562e-04  4.303536e-04  4.484241e-04
## ASV10678    -3.222201e-37 -1.966901e-03 -2.058746e-03 -2.154494e-03
## ASV0944      4.904575e-38  3.079517e-04  3.226522e-04  3.381020e-04
## ASV2292      2.670896e-37  1.603679e-03  1.677355e-03  1.754002e-03
## ASV1090      1.068937e-37  6.445111e-04  6.740677e-04  7.050187e-04
## ASV9117     -8.353717e-38 -4.619769e-04 -4.813255e-04 -5.013938e-04
## ASV0285     -1.088630e-37 -7.429450e-04 -7.812212e-04 -8.214240e-04
## ASV0463     -7.886743e-38 -4.601199e-04 -4.805244e-04 -5.017794e-04
## ASV3199      1.014302e-37  5.861064e-04  6.118684e-04  6.386675e-04
## ASV0150     -1.234046e-38 -8.691275e-05 -9.152946e-05 -9.635571e-05
## ASV6583     -8.712672e-38 -4.942111e-04 -5.153813e-04 -5.375980e-04
## ASV0392      8.854375e-39  4.982015e-05  5.188429e-05  5.407527e-05
## ASV14007    -1.199656e-37 -7.201223e-04 -7.532461e-04 -7.876342e-04
## ASV0177     -5.704741e-38 -3.398868e-04 -3.553331e-04 -3.714317e-04
## ASV6448     -7.463725e-38 -5.039529e-04 -5.297938e-04 -5.568407e-04
## ASV5399     -4.904931e-37 -3.137390e-03 -3.290703e-03 -3.450916e-03
## ASV0277     -1.271209e-38 -7.539408e-05 -7.888630e-05 -8.243241e-05
## ASV2599      1.022425e-37  4.623241e-04  4.764225e-04  4.906461e-04
## ASV13465    -4.767511e-38 -2.481861e-04 -2.580400e-04 -2.679780e-04
## ASV2412      3.036561e-38  1.859108e-04  1.945917e-04  2.036684e-04
## ASV0423     -1.381358e-38 -7.197817e-05 -7.475438e-05 -7.758519e-05
## ASV5187      1.820675e-37  1.004680e-03  1.046937e-03  1.090462e-03
## ASV0701     -1.027818e-37 -6.326594e-04 -6.623949e-04 -6.934723e-04
## ASV4248      5.177993e-38  3.373760e-04  3.541209e-04  3.716358e-04
## ASV0519      9.542346e-38  5.951141e-04  6.233755e-04  6.529853e-04
## ASV0764      2.479811e-38  1.567015e-04  1.642343e-04  1.721287e-04
## ASV5385     -8.604804e-38 -5.323826e-04 -5.575389e-04 -5.838469e-04
## ASV3021     -1.674323e-37 -9.411325e-04 -9.817319e-04 -1.023515e-03
## ASV4119     -3.931069e-37 -2.373408e-03 -2.483381e-03 -2.597772e-03
## ASV2534     -9.613745e-39 -8.829237e-05 -9.400102e-05 -9.981742e-05
## ASV1061      8.995275e-38  5.847969e-04  6.136957e-04  6.440689e-04
## ASV0670     -2.615177e-38 -1.602765e-04 -1.677943e-04 -1.756305e-04
## ASV1384      1.053829e-37  6.823969e-04  7.161078e-04  7.513072e-04
## ASV1981      2.695282e-37  1.674498e-03  1.754020e-03  1.837073e-03
## ASV9632     -7.204524e-38 -3.707737e-04 -3.851772e-04 -3.997903e-04
## ASV4564      8.070990e-38  4.950051e-04  5.182425e-04  5.424467e-04
## ASV5289     -4.759924e-38 -3.049108e-04 -3.197692e-04 -3.354003e-04
## ASV0516      1.920113e-37  1.173491e-03  1.228336e-03  1.285501e-03
## ASV1463     -2.704559e-37 -1.647475e-03 -1.724482e-03 -1.804521e-03
## ASV0969      1.136971e-38  6.514650e-05  6.799448e-05  7.093098e-05
## ASV1113     -6.127243e-38 -3.753544e-04 -3.928743e-04 -4.112122e-04
## ASV1234     -6.429455e-38 -4.354083e-04 -4.576837e-04 -4.812443e-04
## ASV3814     -2.367292e-38 -2.385109e-04 -2.537641e-04 -2.701309e-04
## ASV1000      1.258896e-37  7.564702e-04  7.911967e-04  8.273475e-04
## ASV0079     -1.123528e-38 -7.770468e-05 -8.175814e-05 -8.602511e-05
## ASV0145      2.731065e-38  1.459758e-04  1.518183e-04  1.578762e-04
## ASV0457     -1.629311e-37 -9.829615e-04 -1.028318e-03 -1.075536e-03
## ASV1485      1.206492e-38  7.671716e-05  8.046764e-05  8.437418e-05
## ASV0535      4.309534e-38  2.879542e-04  3.026085e-04  3.179165e-04
## ASV0259     -8.986826e-38 -5.468314e-04 -5.722851e-04 -5.987907e-04
## ASV0570      2.513888e-38  1.635119e-04  1.715698e-04  1.800663e-04
## ASV0906      1.057052e-37  6.320656e-04  6.609445e-04  6.909976e-04
## ASV1748      1.249950e-37  6.514733e-04  6.766053e-04  7.024084e-04
## ASV5520     -1.194000e-37 -7.981965e-04 -8.387080e-04 -8.811502e-04
## ASV2288     -3.377115e-37 -2.062680e-03 -2.159163e-03 -2.259648e-03
## ASV1887     -5.367427e-38 -3.969655e-04 -4.185593e-04 -4.413170e-04
## ASV0374     -1.648548e-38 -9.051340e-05 -9.436284e-05 -9.825608e-05
## ASV0823      2.060452e-37  1.220586e-03  1.275778e-03  1.333281e-03
## ASV0717      1.453928e-38  8.957513e-05  9.385033e-05  9.825404e-05
## ASV0431     -3.898732e-38 -2.425993e-04 -2.541962e-04 -2.662623e-04
## ASV1030      4.475689e-37  2.786036e-03  2.918432e-03  3.056917e-03
## ASV1082     -5.908727e-38 -3.644127e-04 -3.815531e-04 -3.994876e-04
## ASV2684      1.676351e-39  4.461175e-05  4.814162e-05  5.197699e-05
## ASV0051      5.656565e-38  3.476904e-04  3.641112e-04  3.811825e-04
## ASV0513     -1.894772e-38 -1.115132e-04 -1.165060e-04 -1.217024e-04
## ASV0581      1.034704e-37  6.352042e-04  6.649895e-04  6.960860e-04
## ASV7282      2.685435e-38  1.932807e-04  2.036251e-04  2.146074e-04
## ASV3009     -8.880667e-38 -5.439061e-04 -5.693869e-04 -5.959568e-04
## ASV2106      8.997726e-38  6.182338e-04  6.501646e-04  6.838466e-04
## ASV1012      7.290822e-38  4.559464e-04  4.777124e-04  5.004390e-04
## ASV0921      7.272467e-38  4.582077e-04  4.803122e-04  5.034103e-04
## ASV0010     -4.390167e-38 -2.712342e-04 -2.840256e-04 -2.973941e-04
## ASV1178      1.914777e-38  1.218787e-04  1.278449e-04  1.340263e-04
## ASV2848     -1.225613e-37 -7.347067e-04 -7.684428e-04 -8.035756e-04
## ASV0586      2.891570e-37  1.799485e-03  1.884853e-03  1.974326e-03
## ASV4225     -5.387505e-37 -2.865637e-03 -2.979917e-03 -3.098248e-03
## ASV2156     -1.638901e-37 -1.013782e-03 -1.061727e-03 -1.111806e-03
## ASV9778     -1.189170e-37 -7.306053e-04 -7.648781e-04 -8.006944e-04
## ASV0493     -2.498071e-37 -1.504509e-03 -1.573805e-03 -1.646009e-03
## ASV3770     -1.804909e-38 -1.613995e-04 -1.713639e-04 -1.818322e-04
## ASV0470      1.698084e-37  1.042647e-03  1.091506e-03  1.142589e-03
## ASV0262     -6.558256e-38 -4.330104e-04 -4.546901e-04 -4.774624e-04
## ASV0998      4.369060e-38  2.708378e-04  2.836595e-04  2.970700e-04
## ASV7708     -2.314678e-38 -1.347747e-04 -1.407608e-04 -1.469589e-04
## ASV0453     -1.781388e-38 -1.076625e-04 -1.126374e-04 -1.178444e-04
## ASV0044      7.166090e-38  4.374938e-04  4.578704e-04  4.791620e-04
## ASV5490      4.363897e-38  2.553332e-04  2.668306e-04  2.786395e-04
## ASV2638     -2.696673e-38 -1.503244e-04 -1.571540e-04 -1.638329e-04
## ASV0829      2.460662e-37  1.508495e-03  1.578927e-03  1.652466e-03
## ASV0601      7.938435e-38  4.973548e-04  5.209710e-04  5.458547e-04
## ASV0234      5.615179e-39  3.708217e-05  3.892790e-05  4.088676e-05
## ASV0133      1.242973e-37  7.637415e-04  7.996636e-04  8.371135e-04
## ASV0323      3.930224e-38  2.478316e-04  2.597864e-04  2.722910e-04
## ASV0854     -2.865597e-38 -1.744254e-04 -1.825060e-04 -1.909678e-04
## ASV0110      7.796997e-38  4.805620e-04  5.032855e-04  5.269400e-04
## ASV0816     -7.550863e-39 -4.728292e-05 -4.956166e-05 -5.192776e-05
## ASV1031     -3.135701e-38 -1.830123e-04 -1.911265e-04 -1.996101e-04
## ASV0144     -3.535332e-38 -2.204663e-04 -2.310490e-04 -2.420556e-04
## ASV0020     -1.581791e-38 -1.014300e-04 -1.064032e-04 -1.116153e-04
## ASV0962     -4.700002e-38 -2.868549e-04 -3.002279e-04 -3.141815e-04
## ASV0794      8.164808e-38  5.249160e-04  5.505655e-04  5.774794e-04
## ASV7117     -8.319600e-38 -5.031441e-04 -5.263567e-04 -5.505876e-04
## ASV1008     -3.793214e-38 -2.386200e-04 -2.500314e-04 -2.620255e-04
## ASV0096      9.988539e-38  6.153921e-04  6.444092e-04  6.746787e-04
## ASV0128     -1.612000e-37 -1.008053e-03 -1.056185e-03 -1.106578e-03
## ASV5232      1.454276e-37  9.231295e-04  9.677539e-04  1.014540e-03
## ASV0031     -1.157024e-38 -7.200799e-05 -7.546890e-05 -7.904948e-05
## ASV1744     -1.586971e-37 -9.818072e-04 -1.028444e-03 -1.077077e-03
## ASV0289      4.520361e-38  2.776967e-04  2.907243e-04  3.043449e-04
## ASV7413     -1.905808e-38 -1.471757e-04 -1.553910e-04 -1.641553e-04
## ASV0822     -2.063278e-37 -1.240163e-03 -1.297087e-03 -1.356406e-03
## ASV8111     -3.427709e-37 -2.051247e-03 -2.145275e-03 -2.243171e-03
## ASV0687      4.167534e-38  2.618030e-04  2.743085e-04  2.874300e-04
## ASV0112     -1.515135e-38 -9.541727e-05 -9.997165e-05 -1.047707e-04
## ASV0987      5.148582e-38  3.233002e-04  3.387799e-04  3.550112e-04
## ASV5332     -4.314002e-38 -2.197817e-04 -2.281060e-04 -2.367215e-04
## ASV1129     -9.721737e-38 -5.985502e-04 -6.266883e-04 -6.561182e-04
## ASV1274     -2.710155e-38 -1.659460e-04 -1.737064e-04 -1.818128e-04
## ASV0119      6.486660e-38  3.992565e-04  4.180606e-04  4.376786e-04
## ASV0890     -3.170310e-39 -2.049734e-05 -2.150757e-05 -2.258081e-05
## ASV0848     -1.205152e-37 -7.413454e-04 -7.764155e-04 -8.128378e-04
## ASV5944     -5.380769e-37 -3.275723e-03 -3.428193e-03 -3.587179e-03
## ASV19741    -1.953147e-37 -1.192982e-03 -1.248551e-03 -1.306654e-03
## ASV0504     -2.520239e-37 -1.514163e-03 -1.583580e-03 -1.656022e-03
## ASV2146     -1.864004e-37 -1.100899e-03 -1.150419e-03 -1.202151e-03
## ASV0089     -4.141380e-38 -2.537751e-04 -2.656740e-04 -2.780746e-04
## ASV2301     -6.611146e-38 -4.096032e-04 -4.289820e-04 -4.492467e-04
## ASV2982     -1.351219e-36 -7.491748e-03 -7.805904e-03 -8.132797e-03
## ASV0891     -7.832928e-38 -4.802519e-04 -5.027526e-04 -5.262435e-04
## ASV0093      8.622854e-38  5.258208e-04  5.503852e-04  5.759646e-04
## ASV0042      2.980870e-38  1.835453e-04  1.921735e-04  2.011953e-04
## ASV0980      1.015460e-37  6.034649e-04  6.307872e-04  6.592482e-04
## ASV0069     -4.550192e-38 -2.802449e-04 -2.934656e-04 -3.072402e-04
## ASV1364     -3.562545e-38 -2.163244e-04 -2.263381e-04 -2.368013e-04
## ASV0524     -1.731138e-37 -1.074760e-03 -1.125621e-03 -1.178918e-03
## ASV0435      2.387541e-37  1.475291e-03  1.544861e-03  1.617643e-03
## ASV0517     -4.727645e-38 -2.914640e-04 -3.051572e-04 -3.194984e-04
## ASV3167     -3.142183e-37 -2.058518e-03 -2.161171e-03 -2.268695e-03
## ASV4280     -2.177095e-37 -1.335480e-03 -1.397949e-03 -1.463313e-03
## ASV1158      7.039571e-38  4.635863e-04  4.867175e-04  5.109419e-04
## ASV2214      7.631016e-38  4.523075e-04  4.727542e-04  4.941539e-04
## ASV0544     -1.153800e-37 -7.205621e-04 -7.548927e-04 -7.908576e-04
## ASV5326     -1.581776e-38 -1.000064e-04 -1.048803e-04 -1.099455e-04
## ASV3765     -9.235149e-38 -5.656565e-04 -5.921085e-04 -6.197385e-04
## ASV4646      7.944306e-39  1.634093e-05  1.575430e-05  1.491079e-05
## ASV0090      7.937057e-39  4.538548e-05  4.734479e-05  4.938386e-05
## ASV3680      1.608251e-37  9.496298e-04  9.922970e-04  1.036783e-03
## ASV0111      1.656553e-38  9.921313e-05  1.037227e-04  1.084449e-04
## ASV0768      2.198746e-38  1.389641e-04  1.456728e-04  1.527004e-04
## ASV4862     -1.573686e-38 -8.527794e-05 -8.870057e-05 -9.224110e-05
## ASV1742     -1.377010e-37 -8.292856e-04 -8.674273e-04 -9.072417e-04
## ASV3701     -5.619869e-38 -3.163943e-04 -3.300000e-04 -3.440713e-04
## ASV2386     -2.507241e-37 -1.558864e-03 -1.634118e-03 -1.711570e-03
## ASV0375     -1.846821e-37 -1.115449e-03 -1.166801e-03 -1.220520e-03
## ASV2796      6.693804e-38  3.900670e-04  4.073618e-04  4.254232e-04
## ASV1369      1.473735e-37  8.697571e-04  9.089010e-04  9.498562e-04
## ASV10272    -2.053603e-37 -1.255309e-03 -1.314483e-03 -1.375691e-03
## ASV10354    -3.058456e-37 -1.869547e-03 -1.957530e-03 -2.048676e-03
## ASV1067      1.013222e-37  6.151499e-04  6.428497e-04  6.725562e-04
## ASV1900      1.621175e-37  1.001497e-03  1.048724e-03  1.098119e-03
## ASV4079     -6.959005e-38 -4.492247e-04 -4.717623e-04 -4.949557e-04
## ASV4149      3.360885e-37  1.997342e-03  2.087716e-03  2.181973e-03
## ASV5140     -3.058456e-37 -1.869547e-03 -1.957433e-03 -2.048572e-03
## ASV10782     5.886497e-39  5.650594e-05  5.980365e-05  6.368809e-05
## ASV4273     -3.311479e-38 -1.846267e-04 -1.927523e-04 -2.007675e-04
## ASV8121      1.370259e-37  8.408254e-04  8.800666e-04  9.212349e-04
## ASV8438     -3.479804e-37 -2.127106e-03 -2.226976e-03 -2.330663e-03
## ASV9390     -3.479804e-37 -2.127106e-03 -2.226812e-03 -2.330484e-03
## ASV1340      2.765142e-37  1.708696e-03  1.789261e-03  1.873545e-03
## ASV2650     -6.507243e-37 -3.960332e-03 -4.144624e-03 -4.336666e-03
## ASV4674      1.735831e-37  1.057070e-03  1.106070e-03  1.157352e-03
## ASV10492     4.434544e-39  1.977126e-05  2.026954e-05  2.081844e-05
## ASV11430    -2.655735e-37 -1.623375e-03 -1.699302e-03 -1.778409e-03
## ASV12135    -2.655735e-37 -1.623375e-03 -1.699177e-03 -1.778272e-03
## ASV14970    -3.266095e-37 -1.996471e-03 -2.089541e-03 -2.186799e-03
## ASV1954      3.958336e-37  2.423955e-03  2.537160e-03  2.655518e-03
## ASV2613      2.517857e-37  1.535264e-03  1.606601e-03  1.681208e-03
## ASV2757      1.615939e-37  9.613802e-04  1.004954e-03  1.050393e-03
## ASV2909     -4.565990e-37 -2.838410e-03 -2.973009e-03 -3.113958e-03
## ASV2954     -1.739621e-38 -1.071091e-04 -1.121982e-04 -1.174546e-04
## ASV2969      1.174792e-37  7.268237e-04  7.611442e-04  7.970496e-04
## ASV3410      4.097552e-38  2.565295e-04  2.686931e-04  2.815333e-04
## ASV3575      8.221096e-38  4.965481e-04  5.193402e-04  5.432295e-04
## ASV4275      2.131955e-37  1.277144e-03  1.335325e-03  1.396135e-03
## ASV4652      4.351763e-38  2.714914e-04  2.842304e-04  2.977494e-04
## ASV4761      1.547781e-37  9.262163e-04  9.683689e-04  1.012398e-03
## ASV6003      1.063178e-37  6.679857e-04  6.999678e-04  7.335293e-04
## ASV6110     -7.493063e-37 -4.580298e-03 -4.794555e-03 -5.017757e-03
## ASV7427      1.321422e-37  7.987203e-04  8.354328e-04  8.738630e-04
## ASV8092     -2.457270e-37 -1.502060e-03 -1.572247e-03 -1.645437e-03
## ASV8169     -7.493063e-37 -4.580298e-03 -4.793971e-03 -5.017119e-03
## ASV9693      1.277408e-37  7.781458e-04  8.142312e-04  8.519946e-04
## ASV10913     8.394460e-38  5.197660e-04  5.444498e-04  5.701618e-04
## ASV1979      7.686665e-38  4.637261e-04  4.849981e-04  5.072451e-04
## ASV3772      1.592468e-37  9.584243e-04  1.002367e-03  1.048271e-03
## ASV0113     -2.056327e-38 -1.274593e-04 -1.334889e-04 -1.397933e-04
## ASV1800     -2.691127e-38 -1.681026e-04 -1.760881e-04 -1.844552e-04
## ASV2335     -5.844772e-37 -3.529482e-03 -3.692307e-03 -3.862342e-03
## ASV0692     -3.694013e-39 -2.344888e-05 -2.460019e-05 -2.579845e-05
## ASV1120      2.022043e-38  1.261690e-04  1.321401e-04  1.384301e-04
## ASV1434     -1.021158e-37 -6.292450e-04 -6.588330e-04 -6.897814e-04
## ASV0076     -4.793051e-38 -2.949952e-04 -3.088528e-04 -3.233365e-04
## ASV0361      1.703294e-37  1.051999e-03  1.101590e-03  1.153467e-03
## ASV2231     -5.179415e-38 -3.341106e-04 -3.505926e-04 -3.678457e-04
## ASV2018     -1.377569e-38 -8.462158e-05 -8.860079e-05 -9.275288e-05
## ASV1529      7.269140e-38  4.541226e-04  4.757802e-04  4.984571e-04
## ASV0841     -2.614525e-38 -1.596352e-04 -1.670686e-04 -1.748391e-04
## ASV2556     -4.758581e-37 -2.923827e-03 -3.060886e-03 -3.204190e-03
## ASV2777      1.675395e-37  9.828180e-04  1.026598e-03  1.072254e-03
## ASV0355      1.189220e-37  7.289754e-04  7.630707e-04  7.987185e-04
## ASV5169     -1.425839e-37 -8.724290e-04 -9.131837e-04 -9.557420e-04
## ASV3091      1.318115e-37  8.181942e-04  8.569629e-04  8.975378e-04
## ASV2435      5.449840e-38  3.325703e-04  3.480653e-04  3.642397e-04
## ASV6822     -2.942060e-37 -1.798971e-03 -1.882818e-03 -1.970485e-03
## ASV12605    -2.829431e-37 -1.746426e-03 -1.828554e-03 -1.914578e-03
## ASV0286     -6.889050e-38 -4.206311e-04 -4.402293e-04 -4.607394e-04
## ASV0074     -2.671419e-38 -1.655397e-04 -1.733697e-04 -1.815567e-04
## ASV2485     -9.831017e-39 -6.722783e-05 -7.074722e-05 -7.445847e-05
## ASV1233     -2.123672e-37 -1.311040e-03 -1.372821e-03 -1.437456e-03
## ASV0356     -5.772665e-38 -3.495212e-04 -3.656565e-04 -3.825324e-04
## ASV2918     -2.399506e-37 -1.465581e-03 -1.533810e-03 -1.605185e-03
## ASV1427     -2.859189e-38 -1.812614e-04 -1.900278e-04 -1.992299e-04
## ASV1409      5.133973e-38  3.208451e-04  3.361428e-04  3.521696e-04
## ASV0770      1.721349e-38  1.024091e-04  1.070371e-04  1.118715e-04
## ASV1403     -1.471209e-37 -9.016516e-04 -9.437692e-04 -9.878399e-04
## ASV0314     -5.195019e-38 -3.141032e-04 -3.285652e-04 -3.436700e-04
## ASV0187     -1.445215e-38 -9.105148e-05 -9.542528e-05 -9.999844e-05
## ASV0313     -7.327158e-38 -4.453709e-04 -4.660208e-04 -4.875845e-04
## ASV1087      1.667204e-37  1.023110e-03  1.070992e-03  1.121079e-03
## ASV1970     -2.545699e-38 -1.557371e-04 -1.630177e-04 -1.706103e-04
## ASV0754      1.826246e-37  1.124737e-03  1.177595e-03  1.232881e-03
## ASV3775     -4.329655e-38 -2.682881e-04 -2.809678e-04 -2.942437e-04
## ASV0132     -3.156685e-38 -1.940743e-04 -2.031714e-04 -2.126914e-04
## ASV2329      2.552733e-38  1.191180e-04  1.229263e-04  1.268286e-04
## ASV0561      4.848264e-38  2.895219e-04  3.026773e-04  3.163907e-04
## ASV0130     -9.511514e-38 -5.860302e-04 -6.135732e-04 -6.423809e-04
## ASV0226      1.208173e-37  7.399736e-04  7.745837e-04  8.107254e-04
## ASV12648    -1.725456e-37 -1.042277e-03 -1.090294e-03 -1.140517e-03
## ASV0204      1.162478e-37  7.121260e-04  7.453850e-04  7.801692e-04
## ASV0767     -5.384427e-38 -3.411765e-04 -3.576749e-04 -3.749805e-04
## ASV0335     -1.085274e-37 -6.635239e-04 -6.944341e-04 -7.267638e-04
## ASV5901     -2.495390e-38 -1.470216e-04 -1.536240e-04 -1.605232e-04
## ASV0596     -1.731983e-39 -2.796886e-06 -2.545736e-06 -2.249931e-06
## ASV9271      7.967192e-38  5.242689e-04  5.504570e-04  5.779233e-04
## ASV0904      6.860958e-38  4.272139e-04  4.475198e-04  4.687744e-04
## ASV15270    -4.057138e-38 -2.733445e-04 -2.872546e-04 -3.018619e-04
## ASV0990     -3.815407e-38 -2.364822e-04 -2.476628e-04 -2.593698e-04
## ASV0155     -8.023859e-38 -4.925366e-04 -5.155843e-04 -5.396988e-04
## ASV0086     -1.595863e-38 -9.817926e-05 -1.027858e-04 -1.076047e-04
## ASV2581     -8.247855e-39 -4.829425e-05 -5.043668e-05 -5.266492e-05
## ASV1579     -6.408492e-38 -4.004131e-04 -4.194933e-04 -4.394826e-04
## ASV7730      6.849012e-53 -1.750436e-05 -1.909984e-05 -2.080411e-05
## ASV0897      9.380923e-39  5.965481e-05  6.254672e-05  6.558105e-05
## ASV1975      4.490421e-37  2.757185e-03  2.886308e-03  3.021413e-03
##                                                                    
## (Intercept)  9.826160e-03  1.028622e-02  1.076742e-02  1.127069e-02
## ASV1236      1.597388e-03  1.670448e-03  1.746705e-03  1.826285e-03
## ASV0421     -7.568553e-04 -7.912414e-04 -8.271124e-04 -8.645251e-04
## ASV0691     -1.559598e-03 -1.628599e-03 -1.700406e-03 -1.775111e-03
## ASV0899      9.250876e-04  9.686682e-04  1.014273e-03  1.061992e-03
## ASV1004      3.596585e-03  3.761509e-03  3.933694e-03  4.113430e-03
## ASV1041     -2.196190e-03 -2.297511e-03 -2.403345e-03 -2.513879e-03
## ASV1058      2.240987e-03  2.343763e-03  2.451069e-03  2.563085e-03
## ASV12542     8.477153e-04  8.860976e-04  9.261272e-04  9.678665e-04
## ASV1294      1.883719e-03  1.970384e-03  2.060892e-03  2.155399e-03
## ASV13113     6.640858e-04  6.958101e-04  7.290552e-04  7.638943e-04
## ASV1318      2.063254e-03  2.158066e-03  2.257070e-03  2.360436e-03
## ASV2269     -3.500352e-03 -3.662155e-03 -3.831178e-03 -4.007722e-03
## ASV2542      1.537256e-03  1.609595e-03  1.685296e-03  1.764509e-03
## ASV2660     -1.559980e-03 -1.631521e-03 -1.706208e-03 -1.784168e-03
## ASV2737      2.923579e-04  3.049428e-04  3.180100e-04  3.315722e-04
## ASV2840      1.962136e-03  2.051292e-03  2.144294e-03  2.241291e-03
## ASV3053      1.651887e-02  1.727316e-02  1.806038e-02  1.888184e-02
## ASV3077      5.823100e-04  6.088284e-04  6.365006e-04  6.653716e-04
## ASV3134      1.105956e-03  1.158342e-03  1.213196e-03  1.270635e-03
## ASV3140      1.351471e-03  1.414709e-03  1.480846e-03  1.550008e-03
## ASV3579      4.382538e-04  4.593482e-04  4.814694e-04  5.046683e-04
## ASV6119     -9.553637e-04 -9.995201e-04 -1.045647e-03 -1.093825e-03
## ASV7557     -1.943405e-03 -2.033221e-03 -2.127044e-03 -2.225039e-03
## ASV8422      4.314020e-04  4.506485e-04  4.706969e-04  4.915753e-04
## ASV1086     -1.033123e-04 -1.078383e-04 -1.125467e-04 -1.174434e-04
## ASV1310      8.303791e-04  8.684459e-04  9.081880e-04  9.496723e-04
## ASV15750    -1.425560e-04 -1.490666e-04 -1.558584e-04 -1.629421e-04
## ASV16905    -3.989717e-04 -4.174101e-04 -4.366710e-04 -4.567885e-04
## ASV2033      1.749330e-03  1.831321e-03  1.917094e-03  2.006815e-03
## ASV2089      7.290145e-04  7.627852e-04  7.980687e-04  8.349282e-04
## ASV2127      2.764333e-03  2.891007e-03  3.023251e-03  3.161289e-03
## ASV2725      2.220039e-03  2.320917e-03  2.426153e-03  2.535912e-03
## ASV2804     -8.262836e-04 -8.644687e-04 -9.043572e-04 -9.460195e-04
## ASV3075      1.855066e-03  1.940463e-03  2.029659e-03  2.122809e-03
## ASV3327      2.518076e-03  2.635905e-03  2.759153e-03  2.888059e-03
## ASV3342      2.075933e-03  2.172824e-03  2.274137e-03  2.380067e-03
## ASV3532     -2.360970e-03 -2.471404e-03 -2.586900e-03 -2.707679e-03
## ASV3600      1.067271e-03  1.116744e-03  1.168449e-03  1.222481e-03
## ASV4013      2.066625e-03  2.161720e-03  2.261036e-03  2.364745e-03
## ASV4136      2.280724e-03  2.384473e-03  2.492711e-03  2.605611e-03
## ASV4195      8.352208e-03  8.738149e-03  9.141302e-03  9.562380e-03
## ASV4407     -3.267066e-03 -3.418019e-03 -3.575703e-03 -3.740396e-03
## ASV4717      3.291202e-04  3.427399e-04  3.568313e-04  3.714020e-04
## ASV6794      1.295856e-03  1.353585e-03  1.413705e-03  1.476300e-03
## ASV8324     -1.673544e-03 -1.750868e-03 -1.831640e-03 -1.916002e-03
## ASV8981     -5.949053e-05 -6.201842e-05 -6.463622e-05 -6.734537e-05
## ASV9859      5.004082e-04  5.248473e-04  5.505098e-04  5.774595e-04
## ASV0936      1.271179e-04  1.335975e-04  1.404176e-04  1.475968e-04
## ASV12683    -3.876646e-05 -4.089011e-05 -4.313574e-05 -4.551067e-05
## ASV1293      1.055535e-03  1.103847e-03  1.154276e-03  1.206906e-03
## ASV13055    -5.809959e-05 -6.061296e-05 -6.321846e-05 -6.591771e-05
## ASV17063    -8.675623e-04 -9.076376e-04 -9.494993e-04 -9.932207e-04
## ASV2228      7.063049e-04  7.389286e-04  7.730061e-04  8.085973e-04
## ASV2769      6.979423e-05  7.314829e-05  7.666717e-05  8.035924e-05
## ASV2803      6.355044e-04  6.637908e-04  6.932470e-04  7.239134e-04
## ASV2896      5.863858e-04  6.137080e-04  6.422782e-04  6.721513e-04
## ASV3062      6.273368e-04  6.571229e-04  6.883217e-04  7.210002e-04
## ASV3107      1.173960e-03  1.228795e-03  1.286143e-03  1.346115e-03
## ASV3265      1.629062e-03  1.703600e-03  1.781405e-03  1.862607e-03
## ASV3666      6.510873e-06  6.707173e-06  6.905231e-06  7.104629e-06
## ASV4497      4.952610e-04  5.179923e-04  5.417295e-04  5.665138e-04
## ASV6914     -1.157066e-04 -1.214075e-04 -1.273938e-04 -1.336799e-04
## ASV0576     -2.108269e-03 -2.202802e-03 -2.301301e-03 -2.403908e-03
## ASV0673      1.545909e-03  1.617973e-03  1.693322e-03  1.772096e-03
## ASV0772      8.960372e-04  9.372930e-04  9.803848e-04  1.025389e-03
## ASV0862     -1.512649e-04 -1.573314e-04 -1.635867e-04 -1.700314e-04
## ASV0898      6.468983e-04  6.775490e-04  7.096408e-04  7.432401e-04
## ASV0910      8.016273e-04  8.392406e-04  8.785923e-04  9.197604e-04
## ASV0964     -8.367768e-04 -8.747647e-04 -9.143939e-04 -9.557278e-04
## ASV10059     5.651856e-04  5.921528e-04  6.204112e-04  6.500230e-04
## ASV10263    -1.321594e-03 -1.382669e-03 -1.446469e-03 -1.513107e-03
## ASV1088      1.290578e-03  1.350951e-03  1.414101e-03  1.480152e-03
## ASV1101      1.540654e-03  1.611326e-03  1.685112e-03  1.762137e-03
## ASV1183      4.648540e-04  4.866170e-04  5.093785e-04  5.331824e-04
## ASV11956     4.189536e-04  4.371794e-04  4.561211e-04  4.757999e-04
## ASV12774    -3.881133e-06 -4.499096e-06 -5.183115e-06 -5.939317e-06
## ASV1321      1.996474e-03  2.090235e-03  2.188341e-03  2.290986e-03
## ASV13793    -9.108182e-04 -9.529074e-04 -9.968742e-04 -1.042796e-03
## ASV14482     1.347337e-05  1.360693e-05  1.370479e-05  1.376203e-05
## ASV15483     3.360018e-04  3.516977e-04  3.681147e-04  3.852851e-04
## ASV2062      1.685376e-03  1.763205e-03  1.844513e-03  1.929445e-03
## ASV2132      1.458511e-03  1.526872e-03  1.598388e-03  1.673198e-03
## ASV2413      1.333163e-03  1.394092e-03  1.457688e-03  1.524056e-03
## ASV2490      4.153058e-03  4.340586e-03  4.536098e-03  4.739892e-03
## ASV2594      4.793732e-04  5.014643e-04  5.245426e-04  5.486496e-04
## ASV2822     -2.407171e-03 -2.518424e-03 -2.634642e-03 -2.756030e-03
## ASV2863      2.620239e-03  2.739665e-03  2.864278e-03  2.994280e-03
## ASV2910      9.086514e-04  9.500468e-04  9.932411e-04  1.038305e-03
## ASV2980      8.748976e-04  9.154374e-04  9.577971e-04  1.002053e-03
## ASV3307      1.906658e-03  1.994765e-03  2.086803e-03  2.182934e-03
## ASV3474      1.147929e-03  1.202018e-03  1.258631e-03  1.317881e-03
## ASV3502      1.394695e-03  1.459421e-03  1.527071e-03  1.597772e-03
## ASV4236      2.043222e-03  2.136200e-03  2.233206e-03  2.334398e-03
## ASV4842     -3.902462e-04 -4.091707e-04 -4.290155e-04 -4.498247e-04
## ASV4894     -9.109074e-04 -9.530050e-04 -9.969811e-04 -1.042913e-03
## ASV5290      7.222776e-04  7.558095e-04  7.908595e-04  8.274930e-04
## ASV5501      3.615768e-04  3.782658e-04  3.957051e-04  4.139269e-04
## ASV5795      4.414224e-04  4.619369e-04  4.833828e-04  5.058008e-04
## ASV5987     -2.548612e-03 -2.666402e-03 -2.789450e-03 -2.917970e-03
## ASV6267     -2.872710e-03 -3.005469e-03 -3.144151e-03 -3.289001e-03
## ASV6862      1.188187e-03  1.241710e-03  1.297502e-03  1.355648e-03
## ASV7145      4.521377e-04  4.718060e-04  4.922473e-04  5.134848e-04
## ASV7673     -9.108640e-04 -9.529573e-04 -9.969288e-04 -1.042856e-03
## ASV7789      3.769287e-04  3.950478e-04  4.140476e-04  4.339718e-04
## ASV7809     -1.940984e-05 -2.012092e-05 -2.084346e-05 -2.157570e-05
## ASV8002     -1.150664e-03 -1.203837e-03 -1.259383e-03 -1.317398e-03
## ASV8205      3.884990e-04  4.063135e-04  4.249167e-04  4.443411e-04
## ASV9155     -3.170481e-04 -3.316325e-04 -3.468599e-04 -3.627557e-04
## ASV9221      2.919107e-05  3.042404e-05  3.170377e-05  3.303169e-05
## ASV9311     -1.847196e-03 -1.932550e-03 -2.021710e-03 -2.114835e-03
## ASV9557     -1.261615e-03 -1.319905e-03 -1.380795e-03 -1.444392e-03
## ASV9936     -2.547643e-03 -2.665342e-03 -2.788289e-03 -2.916701e-03
## ASV1445      1.663768e-03  1.741199e-03  1.822150e-03  1.906773e-03
## ASV4232      7.328765e-04  7.674431e-04  8.036267e-04  8.415018e-04
## ASV6479      1.038482e-04  1.096512e-04  1.158134e-04  1.223595e-04
## ASV0142     -1.060883e-03 -1.109183e-03 -1.159578e-03 -1.212150e-03
## ASV0378     -5.046339e-05 -5.219178e-05 -5.394019e-05 -5.570395e-05
## ASV1122      1.635749e-03  1.712053e-03  1.791844e-03  1.875272e-03
## ASV0123     -9.391140e-04 -9.818319e-04 -1.026399e-03 -1.072888e-03
## ASV2064      5.428489e-04  5.669733e-04  5.920954e-04  6.182502e-04
## ASV4459     -2.347598e-04 -2.458883e-04 -2.575377e-04 -2.697316e-04
## ASV0448      3.495997e-04  3.663625e-04  3.839321e-04  4.023473e-04
## ASV0397      7.607336e-04  7.961328e-04  8.331389e-04  8.718210e-04
## ASV0485      1.001426e-03  1.047538e-03  1.095699e-03  1.145993e-03
## ASV1566      1.585802e-03  1.659257e-03  1.736018e-03  1.816225e-03
## ASV1365      1.017496e-03  1.064308e-03  1.113196e-03  1.164247e-03
## ASV1065      1.901501e-03  1.989896e-03  2.082296e-03  2.178874e-03
## ASV0722     -1.094337e-04 -1.145399e-04 -1.198818e-04 -1.254701e-04
## ASV12660    -1.050870e-03 -1.098886e-03 -1.148996e-03 -1.201283e-03
## ASV0223      1.598481e-04  1.672723e-04  1.750316e-04  1.831401e-04
## ASV0229      3.944790e-04  4.130312e-04  4.324436e-04  4.527548e-04
## ASV0877      4.140227e-05  4.284204e-05  4.430694e-05  4.579499e-05
## ASV0983      1.016675e-03  1.063273e-03  1.111919e-03  1.162695e-03
## ASV0626     -8.330712e-05 -8.631965e-05 -8.938771e-05 -9.250613e-05
## ASV4146     -5.419973e-05 -5.692235e-05 -5.978592e-05 -6.279801e-05
## ASV4175     -1.216078e-03 -1.272797e-03 -1.332101e-03 -1.394101e-03
## ASV2082     -5.611174e-04 -5.883330e-04 -6.168939e-04 -6.468691e-04
## ASV2272      5.552220e-04  5.808253e-04  6.075718e-04  6.355091e-04
## ASV2245     -8.853867e-04 -9.267320e-04 -9.699659e-04 -1.015170e-03
## ASV0590     -7.221205e-04 -7.572365e-04 -7.940943e-04 -8.327832e-04
## ASV0217     -1.035971e-04 -1.071900e-04 -1.108323e-04 -1.145156e-04
## ASV0416      7.022501e-04  7.336301e-04  7.663125e-04  8.003419e-04
## ASV1056      7.828367e-04  8.197578e-04  8.584032e-04  8.988518e-04
## ASV7777     -1.180871e-03 -1.236302e-03 -1.294295e-03 -1.354964e-03
## ASV0455      1.505811e-04  1.575692e-04  1.648714e-04  1.725010e-04
## ASV0604      4.730865e-04  4.957129e-04  5.194248e-04  5.442746e-04
## ASV6100     -8.372624e-04 -8.766040e-04 -9.177669e-04 -9.608328e-04
## ASV11359    -1.883121e-03 -1.970389e-03 -2.061580e-03 -2.156858e-03
## ASV6604      3.354666e-04  3.513152e-04  3.679072e-04  3.852770e-04
## ASV5004     -5.343570e-04 -5.593638e-04 -5.855182e-04 -6.128705e-04
## ASV1483     -3.352485e-04 -3.510677e-04 -3.676243e-04 -3.849514e-04
## ASV9773     -8.369583e-04 -8.761234e-04 -9.170866e-04 -9.599272e-04
## ASV4059      6.107607e-04  6.401871e-04  6.710475e-04  7.034134e-04
## ASV1193      1.022663e-03  1.070029e-03  1.119527e-03  1.171247e-03
## ASV4610     -1.485254e-04 -1.545455e-04 -1.607546e-04 -1.671529e-04
## ASV0742     -2.378440e-04 -2.479877e-04 -2.585056e-04 -2.694056e-04
## ASV1502      3.161675e-05  3.246957e-05  3.330486e-05  3.411685e-05
## ASV0195     -3.369557e-05 -3.555060e-05 -3.751737e-05 -3.960333e-05
## ASV1213      8.832560e-04  9.233410e-04  9.651499e-04  1.008748e-03
## ASV1648     -7.846013e-04 -8.214217e-04 -8.599429e-04 -9.002409e-04
## ASV6984     -7.307833e-04 -7.650657e-04 -8.009299e-04 -8.384462e-04
## ASV0396     -9.079573e-05 -9.402400e-05 -9.730882e-05 -1.006447e-04
## ASV4297      1.239001e-03  1.295264e-03  1.353954e-03  1.415167e-03
## ASV2622      1.624461e-03  1.698740e-03  1.776271e-03  1.857184e-03
## ASV3512      5.485666e-04  5.747733e-04  6.022365e-04  6.310169e-04
## ASV2411      9.806822e-04  1.026833e-03  1.075126e-03  1.125659e-03
## ASV2291     -5.056720e-04 -5.305426e-04 -5.566735e-04 -5.841319e-04
## ASV0807      1.130229e-03  1.183613e-03  1.239493e-03  1.297982e-03
## ASV1292      3.824994e-04  3.998806e-04  4.180109e-04  4.369189e-04
## ASV1035      1.096151e-03  1.146059e-03  1.198130e-03  1.252447e-03
## ASV0070     -4.204618e-05 -4.363653e-05 -4.526501e-05 -4.693014e-05
## ASV0255      1.054968e-04  1.101492e-04  1.149873e-04  1.200164e-04
## ASV0057     -4.075096e-04 -4.258588e-04 -4.449845e-04 -4.649148e-04
## ASV0077     -7.169546e-05 -7.473194e-05 -7.787871e-05 -8.113803e-05
## ASV0625      7.934809e-04  8.295203e-04  8.671132e-04  9.063188e-04
## ASV2464      5.302191e-03  5.543201e-03  5.794614e-03  6.056829e-03
## ASV1315      1.554733e-03  1.627115e-03  1.702797e-03  1.781923e-03
## ASV2673      1.320693e-03  1.383219e-03  1.448687e-03  1.517235e-03
## ASV2161      5.683065e-04  5.951256e-04  6.232000e-04  6.525878e-04
## ASV0337     -3.064594e-04 -3.207548e-04 -3.357035e-04 -3.513344e-04
## ASV7680     -1.904216e-03 -1.993567e-03 -2.087045e-03 -2.184832e-03
## ASV0611      9.976150e-04  1.044420e-03  1.093387e-03  1.144613e-03
## ASV3118     -1.178813e-03 -1.234651e-03 -1.293115e-03 -1.354327e-03
## ASV1284      7.591364e-04  7.949402e-04  8.323943e-04  8.715693e-04
## ASV0889      7.321203e-04  7.656302e-04  8.006125e-04  8.371264e-04
## ASV4649     -4.052151e-04 -4.241171e-04 -4.438813e-04 -4.645450e-04
## ASV1108     -9.072791e-04 -9.505613e-04 -9.959086e-04 -1.043419e-03
## ASV0738      1.918793e-04  2.023963e-04  2.135396e-04  2.253499e-04
## ASV0473     -8.233892e-05 -8.654552e-05 -9.097933e-05 -9.565363e-05
## ASV0598     -5.488630e-04 -5.737630e-04 -5.997354e-04 -6.268213e-04
## ASV0429      7.808230e-04  8.166716e-04  8.541017e-04  8.931772e-04
## ASV1549      1.001768e-03  1.049323e-03  1.099128e-03  1.151288e-03
## ASV1203      8.550826e-04  8.943467e-04  9.353443e-04  9.781455e-04
## ASV4532      1.515961e-05  1.552628e-05  1.587925e-05  1.621529e-05
## ASV0274     -1.375919e-04 -1.433513e-04 -1.493152e-04 -1.554874e-04
## ASV0163     -7.208984e-04 -7.535730e-04 -7.876511e-04 -8.231859e-04
## ASV1298      2.968782e-04  3.102145e-04  3.241126e-04  3.385929e-04
## ASV9424     -1.640594e-03 -1.717749e-03 -1.798484e-03 -1.882961e-03
## ASV0412      1.428564e-03  1.494247e-03  1.562837e-03  1.634455e-03
## ASV0284      3.618748e-04  3.779410e-04  3.946639e-04  4.120652e-04
## ASV0620     -3.712118e-04 -3.894192e-04 -4.085404e-04 -4.286229e-04
## ASV0153     -1.132999e-03 -1.186644e-03 -1.242813e-03 -1.301625e-03
## ASV0498      4.322125e-04  4.529032e-04  4.745843e-04  4.973026e-04
## ASV0097      2.933854e-04  3.072442e-04  3.217525e-04  3.369405e-04
## ASV0104     -1.968945e-03 -2.060003e-03 -2.155147e-03 -2.254551e-03
## ASV1282      5.166233e-04  5.407552e-04  5.659855e-04  5.923607e-04
## ASV3883     -5.767961e-04 -6.043617e-04 -6.332457e-04 -6.635108e-04
## ASV0801      3.684666e-04  3.860977e-04  4.045740e-04  4.239357e-04
## ASV1611     -1.339225e-03 -1.402252e-03 -1.468209e-03 -1.537227e-03
## ASV0227     -2.802002e-04 -2.938032e-04 -3.080772e-04 -3.230562e-04
## ASV0833      3.862686e-04  4.043966e-04  4.233624e-04  4.432035e-04
## ASV0718      1.895618e-03  1.984058e-03  2.076537e-03  2.173231e-03
## ASV1139      2.704362e-04  2.821031e-04  2.942127e-04  3.067760e-04
## ASV0766     -3.229043e-04 -3.383337e-04 -3.545018e-04 -3.714438e-04
## ASV2091      1.999992e-03  2.090498e-03  2.184881e-03  2.283287e-03
## ASV1238     -7.207635e-04 -7.521449e-04 -7.847714e-04 -8.186828e-04
## ASV9193     -2.290201e-04 -2.421561e-04 -2.561022e-04 -2.709108e-04
## ASV0290      4.122255e-05  4.273423e-05  4.427756e-05  4.585061e-05
## ASV0231      6.245709e-04  6.533274e-04  6.833606e-04  7.147230e-04
## ASV0185      2.236613e-04  2.351021e-04  2.471584e-04  2.598657e-04
## ASV2330      5.863333e-04  6.127164e-04  6.402132e-04  6.688641e-04
## ASV3119     -3.116049e-04 -3.269998e-04 -3.431779e-04 -3.601806e-04
## ASV2368     -8.307005e-04 -8.701655e-04 -9.115001e-04 -9.547922e-04
## ASV0122     -2.805279e-04 -2.932969e-04 -3.066202e-04 -3.205197e-04
## ASV1044      8.908846e-04  9.333133e-04  9.777614e-04  1.024325e-03
## ASV0160     -4.751086e-04 -4.963855e-04 -5.185529e-04 -5.416425e-04
## ASV0326      1.334589e-04  1.396549e-04  1.461311e-04  1.528995e-04
## ASV1388      2.342292e-03  2.450513e-03  2.563578e-03  2.681690e-03
## ASV0792      1.426507e-03  1.491875e-03  1.560116e-03  1.631346e-03
## ASV0036     -3.674918e-04 -3.848505e-04 -4.030223e-04 -4.220447e-04
## ASV2125      1.298722e-03  1.358617e-03  1.421183e-03  1.486529e-03
## ASV1075      6.053433e-05  6.342167e-05  6.644743e-05  6.961837e-05
## ASV0390      6.844083e-04  7.171963e-04  7.515628e-04  7.875842e-04
## ASV3790     -1.058433e-03 -1.107769e-03 -1.159356e-03 -1.213291e-03
## ASV1535     -1.826006e-04 -1.920849e-04 -2.020888e-04 -2.126428e-04
## ASV0263      9.629822e-04  1.007651e-03  1.054334e-03  1.103115e-03
## ASV0675      1.835723e-03  1.922285e-03  2.012884e-03  2.107704e-03
## ASV3348      1.917587e-04  2.010177e-04  2.107298e-04  2.209176e-04
## ASV0058     -6.261060e-04 -6.547267e-04 -6.846010e-04 -7.157790e-04
## ASV4142      7.504017e-04  7.847880e-04  8.206870e-04  8.581594e-04
## ASV0059     -5.190970e-04 -5.427356e-04 -5.674011e-04 -5.931335e-04
## ASV0013     -7.080539e-04 -7.408885e-04 -7.752050e-04 -8.110666e-04
## ASV0033     -3.496618e-04 -3.661964e-04 -3.835072e-04 -4.016301e-04
## ASV4354     -4.723453e-04 -4.943619e-04 -5.173827e-04 -5.414512e-04
## ASV0022     -2.760393e-04 -2.891122e-04 -3.028006e-04 -3.171332e-04
## ASV0134     -2.975901e-04 -3.118151e-04 -3.267226e-04 -3.423455e-04
## ASV0415      2.163292e-05  2.332796e-05  2.516167e-05  2.714538e-05
## ASV10103    -1.662627e-03 -1.740822e-03 -1.822646e-03 -1.908261e-03
## ASV1613      1.298359e-03  1.357710e-03  1.419657e-03  1.484302e-03
## ASV0135     -2.145726e-04 -2.241348e-04 -2.340911e-04 -2.444548e-04
## ASV0469     -1.639176e-03 -1.714274e-03 -1.792675e-03 -1.874511e-03
## ASV0471      1.183532e-03  1.239116e-03  1.297267e-03  1.358100e-03
## ASV0451     -1.681595e-04 -1.766595e-04 -1.856100e-04 -1.950366e-04
## ASV0747      4.125866e-04  4.321806e-04  4.527001e-04  4.741880e-04
## ASV1314     -5.144452e-04 -5.390156e-04 -5.647620e-04 -5.917409e-04
## ASV0425     -2.366416e-03 -2.473395e-03 -2.584949e-03 -2.701251e-03
## ASV0559     -6.663591e-04 -6.968446e-04 -7.286695e-04 -7.618877e-04
## ASV0148     -3.796434e-04 -3.965191e-04 -4.140886e-04 -4.323752e-04
## ASV0129     -1.268466e-04 -1.316037e-04 -1.364723e-04 -1.414480e-04
## ASV1072      2.681619e-04  2.799814e-04  2.922788e-04  3.050697e-04
## ASV2390      8.992160e-04  9.397277e-04  9.819542e-04  1.025958e-03
## ASV0548      7.800369e-04  8.162191e-04  8.540357e-04  8.935568e-04
## ASV0168     -5.287776e-04 -5.529652e-04 -5.782139e-04 -6.045661e-04
## ASV0066     -4.316396e-04 -4.516310e-04 -4.725216e-04 -4.943496e-04
## ASV0468     -2.780788e-04 -2.910456e-04 -3.046040e-04 -3.187797e-04
## ASV0172     -1.370714e-04 -1.429289e-04 -1.490051e-04 -1.553051e-04
## ASV0236     -2.620871e-04 -2.726563e-04 -2.835578e-04 -2.947929e-04
## ASV0250      2.687564e-04  2.828279e-04  2.976820e-04  3.133652e-04
## ASV0338      2.636307e-04  2.766751e-04  2.903817e-04  3.047854e-04
## ASV0450     -2.124156e-05 -2.242488e-05 -2.368061e-05 -2.501365e-05
## ASV0377      5.969448e-04  6.246059e-04  6.535123e-04  6.837166e-04
## ASV1022      7.683951e-05  8.044126e-05  8.420919e-05  8.815072e-05
## ASV6174     -6.846060e-05 -7.181965e-05 -7.534725e-05 -7.905213e-05
## ASV0786      5.835444e-05  6.065573e-05  6.302195e-05  6.545214e-05
## ASV0053     -5.490148e-04 -5.746690e-04 -6.014985e-04 -6.295550e-04
## ASV0697     -4.444886e-04 -4.647503e-04 -4.858948e-04 -5.079569e-04
## ASV0785      8.228106e-04  8.606292e-04  9.001255e-04  9.413686e-04
## ASV1967     -7.567566e-04 -7.914222e-04 -8.276110e-04 -8.653841e-04
## ASV0385      9.793326e-05  1.030686e-04  1.084876e-04  1.142064e-04
## ASV0295      2.624694e-05  2.786811e-05  2.960061e-05  3.145279e-05
## ASV0072     -5.352292e-04 -5.595337e-04 -5.848875e-04 -6.113310e-04
## ASV0157     -2.002223e-04 -2.089642e-04 -2.180484e-04 -2.274844e-04
## ASV0501      1.343087e-03  1.406987e-03  1.473906e-03  1.543985e-03
## ASV10729    -1.595512e-03 -1.670421e-03 -1.748794e-03 -1.830786e-03
## ASV1470      9.693875e-04  1.011271e-03  1.054770e-03  1.099929e-03
## ASV0050     -1.246334e-03 -1.303754e-03 -1.363731e-03 -1.426371e-03
## ASV0411     -2.259045e-04 -2.363289e-04 -2.472209e-04 -2.586006e-04
## ASV0549      3.951236e-04  4.137140e-04  4.331697e-04  4.535302e-04
## ASV0184      1.238843e-04  1.296037e-04  1.355786e-04  1.418199e-04
## ASV0705      3.195663e-04  3.345027e-04  3.501229e-04  3.664567e-04
## ASV1715      7.232006e-04  7.568406e-04  7.920078e-04  8.287682e-04
## ASV0603      1.130425e-04  1.184174e-04  1.240475e-04  1.299451e-04
## ASV0826      9.886017e-04  1.033955e-03  1.081308e-03  1.130743e-03
## ASV0034     -3.993617e-04 -4.176221e-04 -4.366816e-04 -4.565719e-04
## ASV0838      5.544878e-04  5.796571e-04  6.059068e-04  6.332773e-04
## ASV0614     -4.541947e-04 -4.752510e-04 -4.972564e-04 -5.202512e-04
## ASV0014     -7.129245e-04 -7.458934e-04 -7.803419e-04 -8.163322e-04
## ASV0585     -5.967160e-05 -6.253562e-05 -6.554024e-05 -6.869279e-05
## ASV0016     -7.477272e-04 -7.823130e-04 -8.184517e-04 -8.562086e-04
## ASV5394     -7.243919e-04 -7.582076e-04 -7.935690e-04 -8.305434e-04
## ASV0666      1.369734e-03  1.432241e-03  1.497473e-03  1.565536e-03
## ASV2085      3.252001e-04  3.384038e-04  3.520277e-04  3.660735e-04
## ASV0003     -5.190839e-04 -5.430720e-04 -5.681351e-04 -5.943185e-04
## ASV0346      1.232862e-04  1.295769e-04  1.362043e-04  1.431874e-04
## ASV0267     -7.238434e-05 -7.530454e-05 -7.831342e-05 -8.141046e-05
## ASV0353      4.132691e-04  4.333182e-04  4.543513e-04  4.764173e-04
## ASV2419      1.423263e-03  1.488623e-03  1.556871e-03  1.628125e-03
## ASV0447      5.847694e-04  6.125332e-04  6.416092e-04  6.720586e-04
## ASV0654      9.689563e-04  1.014087e-03  1.061271e-03  1.110598e-03
## ASV0151      7.673100e-05  8.067182e-05  8.482667e-05  8.920811e-05
## ASV0065     -3.968209e-04 -4.149038e-04 -4.337735e-04 -4.534607e-04
## ASV0527      1.049466e-03  1.098088e-03  1.148900e-03  1.201994e-03
## ASV4055     -2.386381e-04 -2.502066e-04 -2.623447e-04 -2.750813e-04
## ASV0166     -5.458244e-04 -5.699222e-04 -5.949984e-04 -6.210851e-04
## ASV0417     -4.046581e-04 -4.229308e-04 -4.419812e-04 -4.618382e-04
## ASV0078     -2.880541e-04 -3.010330e-04 -3.145626e-04 -3.286632e-04
## ASV0322     -3.519538e-04 -3.668837e-04 -3.823644e-04 -3.984087e-04
## ASV0156     -6.629551e-04 -6.931863e-04 -7.247380e-04 -7.576628e-04
## ASV0648     -2.007456e-03 -2.101765e-03 -2.200443e-03 -2.303685e-03
## ASV0407     -5.686751e-05 -5.965116e-05 -6.257262e-05 -6.563869e-05
## ASV2030     -2.733646e-04 -2.859071e-04 -2.990044e-04 -3.126795e-04
## ASV0300      1.683066e-04  1.765280e-04  1.851576e-04  1.942162e-04
## ASV1150     -1.653980e-05 -1.719807e-05 -1.787569e-05 -1.857252e-05
## ASV0958      5.035764e-04  5.275929e-04  5.527556e-04  5.791193e-04
## ASV0216     -5.861402e-04 -6.130043e-04 -6.410515e-04 -6.703298e-04
## ASV0446      8.583372e-04  8.989768e-04  9.415262e-04  9.860736e-04
## ASV0367     -6.478555e-04 -6.781473e-04 -7.098293e-04 -7.429630e-04
## ASV0200     -3.651384e-04 -3.819940e-04 -3.996039e-04 -4.179996e-04
## ASV0334     -2.297331e-04 -2.396453e-04 -2.499357e-04 -2.606141e-04
## ASV1311      2.435746e-04  2.546286e-04  2.661584e-04  2.781821e-04
## ASV0458      5.266685e-04  5.504107e-04  5.751589e-04  6.009497e-04
## ASV1371      5.429670e-05  5.689764e-05  5.962346e-05  6.248014e-05
## ASV0418      1.280969e-03  1.338366e-03  1.398171e-03  1.460470e-03
## ASV0004      1.236703e-04  1.292852e-04  1.351421e-04  1.412505e-04
## ASV1943      4.379229e-03  4.576836e-03  4.782858e-03  4.997612e-03
## ASV1495     -1.786529e-04 -1.880913e-04 -1.980637e-04 -2.086030e-04
## ASV0901     -8.020062e-04 -8.397383e-04 -8.792241e-04 -9.205432e-04
## ASV0628      3.786035e-04  3.957052e-04  4.135346e-04  4.321186e-04
## ASV0400      1.963113e-04  2.054089e-04  2.149152e-04  2.248473e-04
## ASV0116     -2.260872e-04 -2.366687e-04 -2.477371e-04 -2.593140e-04
## ASV0788      1.604623e-03  1.679795e-03  1.758429e-03  1.840678e-03
## ASV0117      1.393741e-04  1.460615e-04  1.530719e-04  1.604210e-04
## ASV3137     -5.219310e-06 -5.412527e-06 -5.609431e-06 -5.809653e-06
## ASV0001      1.494894e-04  1.562277e-04  1.632524e-04  1.705741e-04
## ASV1651      3.850786e-04  4.023482e-04  4.203431e-04  4.390892e-04
## ASV1692      1.337328e-03  1.400206e-03  1.466001e-03  1.534845e-03
## ASV0660      4.528245e-04  4.729658e-04  4.939324e-04  5.157512e-04
## ASV0508     -6.597386e-06 -7.068170e-06 -7.575341e-06 -8.121815e-06
## ASV1660     -3.830238e-04 -4.014272e-04 -4.207203e-04 -4.409463e-04
## ASV0233      2.864509e-04  2.997268e-04  3.136014e-04  3.281001e-04
## ASV1343     -9.026644e-04 -9.450803e-04 -9.894625e-04 -1.035900e-03
## ASV0209      4.208336e-04  4.399371e-04  4.598638e-04  4.806451e-04
## ASV0193     -5.756752e-04 -6.008566e-04 -6.270391e-04 -6.542536e-04
## ASV0357      1.025382e-04  1.075949e-04  1.129082e-04  1.184919e-04
## ASV0198      3.332816e-04  3.489089e-04  3.652559e-04  3.823542e-04
## ASV0007      1.567256e-04  1.637641e-04  1.710994e-04  1.787422e-04
## ASV1772     -2.277397e-04 -2.380577e-04 -2.488170e-04 -2.600339e-04
## ASV0009      1.466860e-04  1.532518e-04  1.600924e-04  1.672176e-04
## ASV0006     -1.617663e-05 -1.708605e-05 -1.805083e-05 -1.907457e-05
## ASV0011     -2.845852e-04 -2.979280e-04 -3.118862e-04 -3.264870e-04
## ASV0015      9.541384e-05  9.970064e-05  1.041679e-04  1.088220e-04
## ASV0017      1.036538e-04  1.083089e-04  1.131599e-04  1.182137e-04
## ASV0235     -3.518181e-04 -3.685753e-04 -3.861283e-04 -4.045144e-04
## ASV0382      1.440093e-04  1.511304e-04  1.586119e-04  1.664724e-04
## ASV2357      1.141933e-03  1.195420e-03  1.251372e-03  1.309896e-03
## ASV0567     -3.042250e-04 -3.182674e-04 -3.329385e-04 -3.482648e-04
## ASV0165      1.995908e-04  2.090015e-04  2.188511e-04  2.291595e-04
## ASV0005      2.452728e-04  2.565318e-04  2.682882e-04  2.805625e-04
## ASV0384     -1.781340e-05 -1.830615e-05 -1.878924e-05 -1.925923e-05
## ASV0002      4.192723e-05  4.386319e-05  4.588568e-05  4.799832e-05
## ASV3017      1.582417e-03  1.654695e-03  1.730132e-03  1.808854e-03
## ASV0091     -6.796740e-07 -6.872155e-07 -6.930154e-07 -6.968315e-07
## ASV0186     -6.381864e-04 -6.678917e-04 -6.989469e-04 -7.314102e-04
## ASV0370      1.866537e-04  1.954793e-04  2.047194e-04  2.143930e-04
## ASV0018      3.345163e-04  3.498956e-04  3.659568e-04  3.827278e-04
## ASV1377      5.079317e-03  5.312358e-03  5.555675e-03  5.809682e-03
## ASV0019      3.502974e-04  3.664097e-04  3.832370e-04  4.008088e-04
## ASV0023     -1.020346e-04 -1.069610e-04 -1.121273e-04 -1.175450e-04
## ASV2194      3.935661e-04  4.116698e-04  4.305801e-04  4.503309e-04
## ASV1155      7.526173e-04  7.877562e-04  8.245002e-04  8.629193e-04
## ASV0510     -5.916846e-04 -6.170476e-04 -6.433714e-04 -6.706814e-04
## ASV2371     -8.585645e-04 -8.973620e-04 -9.378140e-04 -9.799821e-04
## ASV0024     -1.384208e-04 -1.450457e-04 -1.519879e-04 -1.592626e-04
## ASV2452      9.916219e-04  1.036326e-03  1.082930e-03  1.131503e-03
## ASV2332     -1.133942e-03 -1.186437e-03 -1.241272e-03 -1.298541e-03
## ASV2591      7.433716e-04  7.799616e-04  8.183992e-04  8.587810e-04
## ASV0521      5.326474e-04  5.577390e-04  5.839983e-04  6.114781e-04
## ASV5542      4.653903e-04  4.873377e-04  5.103079e-04  5.343473e-04
## ASV0336     -1.762825e-04 -1.839740e-04 -1.919724e-04 -2.002877e-04
## ASV10102     9.773001e-04  1.023412e-03  1.071678e-03  1.122197e-03
## ASV16823    -1.433642e-03 -1.498298e-03 -1.565700e-03 -1.635950e-03
## ASV3104      7.911102e-03  8.267857e-03  8.639762e-03  9.027376e-03
## ASV0781      8.977182e-04  9.396586e-04  9.835201e-04  1.029387e-03
## ASV10899     5.497672e-04  5.768477e-04  6.052982e-04  6.351906e-04
## ASV11222    -2.503853e-03 -2.616760e-03 -2.734462e-03 -2.857135e-03
## ASV11327    -2.251904e-03 -2.353442e-03 -2.459291e-03 -2.569609e-03
## ASV12458    -2.503461e-03 -2.616333e-03 -2.733995e-03 -2.856626e-03
## ASV1636      1.956087e-04  2.049884e-04  2.148198e-04  2.251245e-04
## ASV1890     -1.625409e-03 -1.698259e-03 -1.774159e-03 -1.853219e-03
## ASV2898      1.904010e-03  1.991454e-03  2.082761e-03  2.178088e-03
## ASV8328      4.904963e-05  5.395151e-05  5.932091e-05  6.520058e-05
## ASV0709     -2.109084e-03 -2.206363e-03 -2.307981e-03 -2.414116e-03
## ASV0856      1.453135e-03  1.522094e-03  1.594310e-03  1.669936e-03
## ASV0909     -1.365672e-04 -1.404063e-04 -1.441868e-04 -1.478849e-04
## ASV0937     -1.221043e-03 -1.277984e-03 -1.337525e-03 -1.399780e-03
## ASV11390    -3.545891e-03 -3.705745e-03 -3.872383e-03 -4.046054e-03
## ASV11966     8.226272e-04  8.621892e-04  9.036680e-04  9.471573e-04
## ASV12990     5.576850e-04  5.836893e-04  6.108793e-04  6.393065e-04
## ASV14797     9.569220e-04  1.000687e-03  1.046369e-03  1.094044e-03
## ASV14904    -5.033412e-03 -5.260320e-03 -5.496859e-03 -5.743381e-03
## ASV15304     4.303391e-04  4.517153e-04  4.741884e-04  4.978170e-04
## ASV16696    -1.780401e-03 -1.860657e-03 -1.944319e-03 -2.031512e-03
## ASV1690      2.950408e-03  3.090334e-03  3.236856e-03  3.390280e-03
## ASV2029      2.149391e-03  2.248301e-03  2.351600e-03  2.459467e-03
## ASV2834      3.441640e-03  3.602166e-03  3.770018e-03  3.945515e-03
## ASV4003      2.041131e-03  2.139185e-03  2.241984e-03  2.349759e-03
## ASV4064      1.297499e-03  1.357657e-03  1.420528e-03  1.486226e-03
## ASV4294      7.119872e-04  7.471144e-04  7.840260e-04  8.228167e-04
## ASV4609      4.033750e-04  4.215616e-04  4.405242e-04  4.602921e-04
## ASV6283     -1.665710e-03 -1.740799e-03 -1.819076e-03 -1.900656e-03
## ASV6491     -2.375202e-03 -2.482266e-03 -2.593873e-03 -2.710191e-03
## ASV7453      1.041589e-03  1.091840e-03  1.144538e-03  1.199803e-03
## ASV7959      2.592225e-04  2.728910e-04  2.873298e-04  3.025858e-04
## ASV8219      2.448089e-02  2.558434e-02  2.673460e-02  2.793341e-02
## ASV8547     -2.130004e-03 -2.226003e-03 -2.326075e-03 -2.430370e-03
## ASV9319      9.035255e-04  9.462385e-04  9.909547e-04  1.037766e-03
## ASV9382     -4.108389e-03 -4.293547e-03 -4.486558e-03 -4.687711e-03
## ASV11516    -2.770529e-03 -2.895381e-03 -3.025529e-03 -3.161165e-03
## ASV14377    -2.011243e-03 -2.101872e-03 -2.196343e-03 -2.294798e-03
## ASV1867      1.664894e-03  1.742968e-03  1.824646e-03  1.910090e-03
## ASV1895      2.857461e-04  2.989846e-04  3.128145e-04  3.272597e-04
## ASV3168      9.254760e-04  9.677369e-04  1.011841e-03  1.057862e-03
## ASV4449      5.910714e-03  6.183906e-03  6.469341e-03  6.767532e-03
## ASV6596      1.104317e-03  1.157830e-03  1.213975e-03  1.272884e-03
## ASV7492     -2.845978e-04 -2.959348e-04 -3.076104e-04 -3.196230e-04
## ASV9854     -5.265702e-04 -5.499767e-04 -5.743454e-04 -5.997086e-04
## ASV6296      4.513618e-02  4.716982e-02  4.928967e-02  5.149890e-02
## ASV4201      4.606041e-04  4.843407e-04  5.093710e-04  5.357706e-04
## ASV0552      1.081767e-03  1.132565e-03  1.185713e-03  1.241316e-03
## ASV3671     -5.640696e-04 -5.894677e-04 -6.159432e-04 -6.435362e-04
## ASV3529     -2.924357e-04 -3.044687e-04 -3.169037e-04 -3.297451e-04
## ASV1060      4.165649e-04  4.361522e-04  4.566487e-04  4.780956e-04
## ASV0239     -4.484169e-04 -4.684117e-04 -4.892321e-04 -5.109058e-04
## ASV5711     -1.737306e-03 -1.816835e-03 -1.899857e-03 -1.986512e-03
## ASV4152     -2.817275e-03 -2.947307e-03 -3.083147e-03 -3.225037e-03
## ASV1461      1.309963e-03  1.369213e-03  1.430994e-03  1.495401e-03
## ASV2877      6.778687e-04  7.084963e-04  7.404292e-04  7.737158e-04
## ASV0012      9.241439e-05  9.672184e-05  1.012256e-04  1.059341e-04
## ASV9823      2.274636e-04  2.363300e-04  2.454513e-04  2.548268e-04
## ASV0008      9.900222e-05  1.035962e-04  1.083977e-04  1.134156e-04
## ASV7832     -1.758057e-03 -1.839648e-03 -1.924926e-03 -2.014049e-03
## ASV1915     -4.198865e-05 -4.343980e-05 -4.491160e-05 -4.640104e-05
## ASV0055      1.229400e-05  1.262620e-05  1.295058e-05  1.326460e-05
## ASV0032      1.878795e-04  1.964521e-04  2.053986e-04  2.147335e-04
## ASV2977     -2.468080e-03 -2.581413e-03 -2.699751e-03 -2.823297e-03
## ASV0466      1.856156e-03  1.939555e-03  2.026465e-03  2.117012e-03
## ASV3866      1.245132e-03  1.303536e-03  1.364637e-03  1.428556e-03
## ASV0040      3.307543e-04  3.461917e-04  3.623347e-04  3.792140e-04
## ASV0496     -1.117468e-04 -1.179719e-04 -1.245760e-04 -1.315841e-04
## ASV0052      4.233339e-04  4.429524e-04  4.634546e-04  4.848779e-04
## ASV3828     -2.609865e-03 -2.730267e-03 -2.856045e-03 -2.987424e-03
## ASV1930      8.186724e-04  8.566567e-04  8.963547e-04  9.378391e-04
## ASV2126      1.012116e-03  1.058742e-03  1.107442e-03  1.158302e-03
## ASV0793      1.143357e-03  1.196856e-03  1.252812e-03  1.311333e-03
## ASV0299     -9.162814e-05 -9.587212e-05 -1.003073e-04 -1.049417e-04
## ASV0208      8.155787e-04  8.540271e-04  8.942672e-04  9.363802e-04
## ASV0511     -4.758315e-04 -4.972831e-04 -5.196457e-04 -5.429529e-04
## ASV1123     -1.515974e-03 -1.583865e-03 -1.654595e-03 -1.728264e-03
## ASV0099     -4.882735e-05 -5.080690e-05 -5.284950e-05 -5.495544e-05
## ASV0752     -4.520697e-04 -4.738479e-04 -4.966856e-04 -5.206351e-04
## ASV0883      5.777877e-04  6.050875e-04  6.336655e-04  6.635802e-04
## ASV0683      1.205001e-03  1.261968e-03  1.321606e-03  1.384039e-03
## ASV4117     -2.989097e-03 -3.126880e-03 -3.270802e-03 -3.421116e-03
## ASV2172      2.434290e-04  2.544237e-04  2.658873e-04  2.778376e-04
## ASV0330     -3.463734e-04 -3.624161e-04 -3.791821e-04 -3.967025e-04
## ASV0728      1.824011e-03  1.908756e-03  1.997337e-03  2.089919e-03
## ASV0499      4.396718e-04  4.604576e-04  4.822186e-04  5.049999e-04
## ASV0120     -7.604224e-04 -7.956746e-04 -8.325153e-04 -8.710115e-04
## ASV1446      7.604208e-04  7.938743e-04  8.286654e-04  8.648349e-04
## ASV17171    -1.357128e-03 -1.420038e-03 -1.485785e-03 -1.554490e-03
## ASV0533      1.241073e-04  1.300833e-04  1.363497e-04  1.429208e-04
## ASV2495     -4.816324e-04 -5.049738e-04 -5.294646e-04 -5.551631e-04
## ASV5582      6.178268e-04  6.445421e-04  6.722830e-04  7.010767e-04
## ASV1488      5.030875e-04  5.281793e-04  5.545529e-04  5.822746e-04
## ASV0682      3.268225e-04  3.424032e-04  3.587269e-04  3.758292e-04
## ASV0068     -3.586127e-04 -3.753532e-04 -3.928583e-04 -4.111613e-04
## ASV1987     -1.328914e-03 -1.392266e-03 -1.458640e-03 -1.528177e-03
## ASV0035     -4.954731e-05 -5.235661e-05 -5.534146e-05 -5.851399e-05
## ASV7192     -1.021030e-03 -1.067502e-03 -1.115988e-03 -1.166566e-03
## ASV0873      4.786924e-04  4.931611e-04  5.075691e-04  5.218493e-04
## ASV4749      1.509614e-05  1.405464e-05  1.280165e-05  1.131271e-05
## ASV2174      9.912353e-04  1.034461e-03  1.079397e-03  1.126098e-03
## ASV1476     -6.238049e-04 -6.530023e-04 -6.835436e-04 -7.154885e-04
## ASV0740     -2.148058e-03 -2.249120e-03 -2.354875e-03 -2.465537e-03
## ASV0170     -2.783839e-04 -2.913630e-04 -3.049340e-04 -3.191226e-04
## ASV2466     -2.089404e-03 -2.186475e-03 -2.287943e-03 -2.393997e-03
## ASV1709      8.795582e-04  9.194597e-04  9.610798e-04  1.004484e-03
## ASV6170     -4.954400e-03 -5.180125e-03 -5.415715e-03 -5.661568e-03
## ASV3673      1.487858e-03  1.554971e-03  1.624960e-03  1.697935e-03
## ASV1745      2.474861e-04  2.567827e-04  2.663150e-04  2.760785e-04
## ASV0380     -1.235397e-03 -1.285885e-03 -1.338064e-03 -1.391960e-03
## ASV0426      5.710002e-05  6.101991e-05  6.522826e-05  6.974675e-05
## ASV0202      1.409357e-06  2.249793e-06  3.200380e-06  4.272454e-06
## ASV6350     -1.650368e-03 -1.723325e-03 -1.799280e-03 -1.878339e-03
## ASV0713     -6.811059e-04 -7.129525e-04 -7.462612e-04 -7.810965e-04
## ASV1822      5.012357e-05  5.318319e-05  5.644301e-05  5.991648e-05
## ASV4569      2.097913e-03  2.192824e-03  2.291820e-03  2.395058e-03
## ASV0030     -1.846539e-04 -1.933859e-04 -2.025261e-04 -2.120932e-04
## ASV0331      7.313070e-04  7.660330e-04  8.024007e-04  8.404869e-04
## ASV2981      2.096749e-03  2.195437e-03  2.298702e-03  2.406751e-03
## ASV0828     -2.825030e-04 -3.018532e-04 -3.226348e-04 -3.449572e-04
## ASV2440      1.829755e-03  1.915684e-03  2.005587e-03  2.099642e-03
## ASV3006     -1.018553e-02 -1.061339e-02 -1.105682e-02 -1.151620e-02
## ASV3875      9.469980e-02  9.867754e-02  1.028000e-01  1.070707e-01
## ASV4511      1.028723e-03  1.077291e-03  1.128131e-03  1.181348e-03
## ASV4700     -3.745186e-03 -3.902485e-03 -4.065508e-03 -4.234391e-03
## ASV5804     -8.794892e-02 -9.164254e-02 -9.547054e-02 -9.943611e-02
## ASV6826      1.475622e-03  1.545735e-03  1.619170e-03  1.696082e-03
## ASV7280      1.367013e-03  1.432936e-03  1.502051e-03  1.574512e-03
## ASV7535     -3.744758e-03 -3.902023e-03 -4.065008e-03 -4.233851e-03
## ASV0651     -7.467669e-04 -7.805729e-04 -8.158236e-04 -8.525724e-04
## ASV0913      1.678142e-03  1.757329e-03  1.840220e-03  1.926984e-03
## ASV10832    -3.995758e-03 -4.163551e-03 -4.337448e-03 -4.517593e-03
## ASV1117     -3.871097e-03 -4.046234e-03 -4.228901e-03 -4.419391e-03
## ASV11329     5.705352e-04  5.998541e-04  6.307512e-04  6.633157e-04
## ASV13209     6.945595e-05  7.645986e-05  8.409559e-05  9.241426e-05
## ASV1345      8.903715e-04  9.334512e-04  9.786139e-04  1.025957e-03
## ASV1719     -5.626786e-03 -5.863051e-03 -6.107908e-03 -6.361562e-03
## ASV1886      1.033690e-03  1.080822e-03  1.130018e-03  1.181363e-03
## ASV2158     -8.134207e-05 -8.090100e-05 -8.009366e-05 -7.887867e-05
## ASV2189      1.733786e-03  1.813958e-03  1.897732e-03  1.985262e-03
## ASV2257      1.802643e-03  1.885234e-03  1.971483e-03  2.061542e-03
## ASV2283      4.358765e-03  4.541756e-03  4.731399e-03  4.927852e-03
## ASV2328      2.685277e-03  2.798003e-03  2.914825e-03  3.035843e-03
## ASV2434     -2.510967e-03 -2.622915e-03 -2.739551e-03 -2.861046e-03
## ASV2648      4.901481e-03  5.107205e-03  5.320403e-03  5.541253e-03
## ASV2698      4.714573e-03  4.934764e-03  5.165059e-03  5.405907e-03
## ASV2775      1.488545e-03  1.554915e-03  1.624045e-03  1.696034e-03
## ASV3171      2.362681e-03  2.461831e-03  2.564580e-03  2.671016e-03
## ASV3227      2.297660e-03  2.399535e-03  2.505593e-03  2.615977e-03
## ASV3397      1.065681e-03  1.116867e-03  1.170496e-03  1.226679e-03
## ASV3444      3.295204e-03  3.441034e-03  3.592875e-03  3.750938e-03
## ASV3556      9.827092e-03  1.023941e-02  1.066668e-02  1.110928e-02
## ASV3606     -2.309767e-02 -2.406670e-02 -2.507090e-02 -2.611110e-02
## ASV4190      3.031598e-03  3.172258e-03  3.319288e-03  3.472963e-03
## ASV4197      1.948021e-03  2.034228e-03  2.123972e-03  2.217373e-03
## ASV4722      2.919144e-03  3.052642e-03  3.192007e-03  3.337476e-03
## ASV4765      1.522367e-03  1.594632e-03  1.670269e-03  1.749424e-03
## ASV4809      5.806616e-03  6.050181e-03  6.302582e-03  6.564027e-03
## ASV4846      2.619932e-03  2.742298e-03  2.870255e-03  3.004043e-03
## ASV4903     -1.572817e-04 -1.601651e-04 -1.628114e-04 -1.651826e-04
## ASV4944     -2.378164e-03 -2.477914e-03 -2.581281e-03 -2.688351e-03
## ASV5151      4.692788e-04  4.697526e-04  4.684219e-04  4.650626e-04
## ASV5413     -5.231472e-03 -5.450886e-03 -5.678257e-03 -5.913774e-03
## ASV5537     -5.620224e-03 -5.855925e-03 -6.100173e-03 -6.353170e-03
## ASV5688      4.723928e-03  4.922026e-03  5.127305e-03  5.339936e-03
## ASV5752      1.332534e-03  1.396619e-03  1.463773e-03  1.534137e-03
## ASV6122     -6.051284e-03 -6.305032e-03 -6.567979e-03 -6.840341e-03
## ASV6135      3.176769e-03  3.309970e-03  3.447999e-03  3.590970e-03
## ASV6188     -1.928803e-02 -2.009671e-02 -2.093470e-02 -2.180269e-02
## ASV6216      4.279167e-03  4.470480e-03  4.669824e-03  4.877491e-03
## ASV6242      3.176112e-03  3.309256e-03  3.447223e-03  3.590128e-03
## ASV6383      1.985893e-02  2.069137e-02  2.155395e-02  2.244740e-02
## ASV6781      4.419604e-03  4.604849e-03  4.796802e-03  4.995621e-03
## ASV6799     -8.392799e-03 -8.744552e-03 -9.109041e-03 -9.486565e-03
## ASV7374     -1.780920e-03 -1.855555e-03 -1.932892e-03 -2.012994e-03
## ASV7539     -2.375998e-03 -2.475564e-03 -2.578734e-03 -2.685593e-03
## ASV8591     -6.046971e-03 -6.300351e-03 -6.562900e-03 -6.834835e-03
## ASV8637      2.654628e-02  2.765854e-02  2.881104e-02  3.000473e-02
## ASV12796    -3.503208e-03 -3.649978e-03 -3.802057e-03 -3.959570e-03
## ASV1934      1.751921e-03  1.833604e-03  1.919018e-03  2.008324e-03
## ASV22549     1.421912e-04  1.517235e-04  1.619329e-04  1.728672e-04
## ASV29857    -1.358829e-03 -1.415755e-03 -1.474740e-03 -1.535832e-03
## ASV3215      1.852542e-03  1.940128e-03  2.031828e-03  2.127833e-03
## ASV3236     -3.502695e-03 -3.649422e-03 -3.801455e-03 -3.958920e-03
## ASV3954     -3.502442e-03 -3.649147e-03 -3.801158e-03 -3.958597e-03
## ASV4850      2.347841e-03  2.446177e-03  2.548068e-03  2.653598e-03
## ASV5225      2.267183e-02  2.362134e-02  2.460517e-02  2.562413e-02
## ASV5532     -1.210957e-03 -1.261669e-03 -1.314213e-03 -1.368633e-03
## ASV7258      8.955423e-04  9.426763e-04  9.924331e-04  1.044967e-03
## ASV9474     -3.903477e-04 -4.033713e-04 -4.165544e-04 -4.298702e-04
## ASV11857    -4.549954e-03 -4.740485e-03 -4.937902e-03 -5.142365e-03
## ASV1202     -2.889405e-03 -3.010391e-03 -3.135748e-03 -3.265580e-03
## ASV14742     7.531798e-04  7.909943e-04  8.307723e-04  8.726197e-04
## ASV16652     5.862169e-04  6.148253e-04  6.448325e-04  6.763046e-04
## ASV2019      2.098521e-03  2.192642e-03  2.290741e-03  2.392964e-03
## ASV2410     -4.611446e-03 -4.824584e-03 -5.047317e-03 -5.280059e-03
## ASV2718      1.131165e-03  1.184991e-03  1.241365e-03  1.300404e-03
## ASV2738      3.446307e-03  3.600465e-03  3.761083e-03  3.928394e-03
## ASV2876      2.100883e-03  2.188838e-03  2.279970e-03  2.374353e-03
## ASV3177      2.815181e-03  2.933032e-03  3.055139e-03  3.181601e-03
## ASV4367      3.478629e-03  3.624243e-03  3.775114e-03  3.931366e-03
## ASV4635      1.026368e-03  1.078270e-03  1.132873e-03  1.190321e-03
## ASV4896      7.324756e-04  7.724283e-04  8.147109e-04  8.594672e-04
## ASV4907      8.742509e-04  9.176757e-04  9.633128e-04  1.011278e-03
## ASV5230     -2.707992e-03 -2.821354e-03 -2.938810e-03 -3.060456e-03
## ASV6509     -2.888396e-03 -3.009301e-03 -3.134572e-03 -3.264311e-03
## ASV7376     -2.066469e-03 -2.152962e-03 -2.242579e-03 -2.335391e-03
## ASV8163     -3.079174e-03 -3.208045e-03 -3.341569e-03 -3.479853e-03
## ASV8195     -2.707210e-03 -2.820505e-03 -2.937890e-03 -3.059459e-03
## ASV8923      8.048694e-04  8.445891e-04  8.863042e-04  9.301158e-04
## ASV9666     -1.478372e-03 -1.534877e-03 -1.592914e-03 -1.652467e-03
## ASV1482      1.377811e-03  1.443217e-03  1.511707e-03  1.583424e-03
## ASV2726      1.265453e-03  1.325723e-03  1.388849e-03  1.454964e-03
## ASV3281     -1.127974e-02 -1.175177e-02 -1.224084e-02 -1.274735e-02
## ASV4235     -1.127892e-02 -1.175089e-02 -1.223988e-02 -1.274631e-02
## ASV4808      2.268859e-03  2.370386e-03  2.476191e-03  2.586434e-03
## ASV4861     -5.565745e-03 -5.813245e-03 -6.071056e-03 -6.339555e-03
## ASV5276      3.238240e-03  3.383056e-03  3.533957e-03  3.691166e-03
## ASV5837      1.030695e-03  1.079097e-03  1.129747e-03  1.182746e-03
## ASV7098      1.485036e-03  1.554400e-03  1.626949e-03  1.702826e-03
## ASV8451     -1.919637e-03 -1.999934e-03 -2.083127e-03 -2.169281e-03
## ASV8694     -1.127444e-02 -1.174601e-02 -1.223458e-02 -1.274054e-02
## ASV0905     -4.723922e-04 -4.952120e-04 -5.191233e-04 -5.441753e-04
## ASV2900      2.579700e-03  2.691763e-03  2.808252e-03  2.929308e-03
## ASV3963     -2.633580e-03 -2.746524e-03 -2.863803e-03 -2.985544e-03
## ASV0041     -4.447453e-04 -4.658147e-04 -4.878738e-04 -5.109678e-04
## ASV1865      1.302092e-03  1.365061e-03  1.431096e-03  1.500345e-03
## ASV1140      7.355386e-04  7.707333e-04  8.076015e-04  8.462201e-04
## ASV1179      7.697756e-04  8.056758e-04  8.432125e-04  8.824565e-04
## ASV0279      1.180813e-03  1.234939e-03  1.291456e-03  1.350463e-03
## ASV0043     -1.995874e-04 -2.094902e-04 -2.199014e-04 -2.308484e-04
## ASV2097     -7.152082e-04 -7.469269e-04 -7.799615e-04 -8.143601e-04
## ASV0309     -1.403831e-04 -1.467264e-04 -1.533417e-04 -1.602393e-04
## ASV0607      1.829066e-03  1.914694e-03  2.004260e-03  2.097938e-03
## ASV0025     -5.074318e-04 -5.313176e-04 -5.563121e-04 -5.824650e-04
## ASV2284     -2.047276e-03 -2.136862e-03 -2.230037e-03 -2.326920e-03
## ASV0556      5.068755e-04  5.315467e-04  5.574342e-04  5.845984e-04
## ASV5040     -1.581250e-03 -1.678459e-03 -1.782103e-03 -1.892624e-03
## ASV2924     -6.609949e-03 -6.894604e-03 -7.190271e-03 -7.497277e-03
## ASV1331      1.629190e-03  1.704699e-03  1.783615e-03  1.866083e-03
## ASV0506     -7.337488e-04 -7.654378e-04 -7.983484e-04 -8.325148e-04
## ASV1514      2.467119e-03  2.581612e-03  2.701274e-03  2.826325e-03
## ASV2144      2.355977e-03  2.465023e-03  2.578975e-03  2.698043e-03
## ASV2265      1.547352e-03  1.619220e-03  1.694343e-03  1.772859e-03
## ASV5156      1.248556e-03  1.300507e-03  1.354288e-03  1.409934e-03
## ASV5534      3.878587e-04  4.032031e-04  4.190088e-04  4.352763e-04
## ASV5747     -2.825290e-04 -3.082979e-04 -3.363323e-04 -3.668197e-04
## ASV6657      1.223292e-03  1.278094e-03  1.335199e-03  1.394693e-03
## ASV0658     -9.212280e-04 -9.614456e-04 -1.003257e-03 -1.046711e-03
## ASV0716      1.627471e-03  1.701114e-03  1.777909e-03  1.857976e-03
## ASV1657      3.186894e-03  3.327067e-03  3.472891e-03  3.624549e-03
## ASV1885      2.741804e-03  2.857536e-03  2.977489e-03  3.101759e-03
## ASV2333      1.403788e-03  1.468127e-03  1.535300e-03  1.605423e-03
## ASV3375      1.110504e-03  1.159674e-03  1.210862e-03  1.264138e-03
## ASV4317      9.693540e-04  1.014525e-03  1.061763e-03  1.111159e-03
## ASV9599     -1.186545e-04 -1.294756e-04 -1.412480e-04 -1.540502e-04
## ASV0175     -1.529432e-03 -1.599042e-03 -1.671669e-03 -1.747429e-03
## ASV1032      6.581113e-04  6.869804e-04  7.170072e-04  7.482291e-04
## ASV1235      1.210018e-03  1.260618e-03  1.313009e-03  1.367227e-03
## ASV1262      1.567658e-03  1.639655e-03  1.714836e-03  1.793332e-03
## ASV1320      8.860165e-04  9.294204e-04  9.749920e-04  1.022842e-03
## ASV13797     9.137816e-04  9.551242e-04  9.982448e-04  1.043213e-03
## ASV1491      1.282175e-03  1.345894e-03  1.412853e-03  1.483217e-03
## ASV15014    -9.228504e-05 -1.006998e-04 -1.098540e-04 -1.198088e-04
## ASV1510      1.785278e-03  1.870739e-03  1.960283e-03  2.054102e-03
## ASV1551      6.111791e-03  6.396426e-03  6.694015e-03  7.005119e-03
## ASV1919      6.145420e-04  6.520488e-04  6.920290e-04  7.346519e-04
## ASV2114      1.145229e-03  1.196133e-03  1.249150e-03  1.304354e-03
## ASV21486    -7.926372e-05 -8.648950e-05 -9.435004e-05 -1.028978e-04
## ASV2448      1.175582e-03  1.228742e-03  1.284183e-03  1.341989e-03
## ASV2589      2.239707e-03  2.338404e-03  2.441105e-03  2.547945e-03
## ASV2608      1.485397e-03  1.553024e-03  1.623594e-03  1.697224e-03
## ASV2786      2.961555e-03  3.098250e-03  3.241084e-03  3.390319e-03
## ASV2827      1.053458e-03  1.101182e-03  1.150958e-03  1.202863e-03
## ASV2872      4.595590e-03  4.800877e-03  5.014716e-03  5.237407e-03
## ASV3125      8.991338e-04  9.391057e-04  9.807300e-04  1.024064e-03
## ASV3247      1.967652e-03  2.055752e-03  2.147547e-03  2.243172e-03
## ASV3451     -2.456219e-04 -2.680125e-04 -2.923700e-04 -3.188569e-04
## ASV3465      6.363797e-05  6.328985e-05  6.263594e-05  6.163883e-05
## ASV3809      2.654874e-03  2.773088e-03  2.896201e-03  3.024388e-03
## ASV4006      1.290693e-03  1.348617e-03  1.408980e-03  1.471872e-03
## ASV4046      1.897465e-03  1.982475e-03  2.071060e-03  2.163350e-03
## ASV4938      1.714773e-04  1.736972e-04  1.755193e-04  1.768856e-04
## ASV5435     -4.168496e-04 -4.548414e-04 -4.961695e-04 -5.411095e-04
## ASV5605      1.108150e-03  1.154297e-03  1.202064e-03  1.251480e-03
## ASV5635     -1.390573e-04 -1.517297e-04 -1.655146e-04 -1.805041e-04
## ASV5743      9.018813e-04  9.426775e-04  9.852254e-04  1.029592e-03
## ASV6627     -1.443318e-04 -1.574839e-04 -1.717907e-04 -1.873474e-04
## ASV6785     -1.606757e-04 -1.753160e-04 -1.912414e-04 -2.085580e-04
## ASV7368      1.111741e-03  1.163348e-03  1.217295e-03  1.273681e-03
## ASV9118      4.095698e-04  4.266338e-04  4.443020e-04  4.625869e-04
## ASV9135      7.644458e-04  7.953133e-04  8.271737e-04  8.600359e-04
## ASV9435      9.169048e-04  9.559506e-04  9.964491e-04  1.038436e-03
## ASV9671     -2.060795e-04 -2.248541e-04 -2.452764e-04 -2.674823e-04
## ASV0387     -1.597928e-03 -1.668451e-03 -1.741838e-03 -1.818182e-03
## ASV0454     -2.558960e-03 -2.673452e-03 -2.792733e-03 -2.916976e-03
## ASV0751     -7.384190e-04 -7.701149e-04 -8.030157e-04 -8.371535e-04
## ASV1081      1.540842e-03  1.612031e-03  1.686399e-03  1.764080e-03
## ASV1332      2.749720e-03  2.874752e-03  3.005192e-03  3.141250e-03
## ASV2659      3.032634e-03  3.173355e-03  3.320415e-03  3.474081e-03
## ASV2979      1.360126e-03  1.420570e-03  1.483505e-03  1.549014e-03
## ASV4184      1.963505e-03  2.047359e-03  2.134358e-03  2.224583e-03
## ASV6198      6.268211e-04  6.545818e-04  6.834874e-04  7.135788e-04
## ASV7454      6.689865e-04  6.986154e-04  7.294555e-04  7.615473e-04
## ASV8198      5.832276e-04  6.062633e-04  6.299855e-04  6.543940e-04
## ASV0855      1.657226e-03  1.733837e-03  1.813884e-03  1.897512e-03
## ASV10092     7.621563e-04  7.960325e-04  8.313103e-04  8.680390e-04
## ASV1532      1.471740e-03  1.541312e-03  1.614145e-03  1.690392e-03
## ASV2553      2.640282e-03  2.762515e-03  2.890245e-03  3.023707e-03
## ASV2741      3.597364e-03  3.768105e-03  3.946896e-03  4.134108e-03
## ASV4095      2.138629e-03  2.243032e-03  2.352587e-03  2.467547e-03
## ASV5295      7.761364e-04  8.095545e-04  8.442527e-04  8.802661e-04
## ASV5787     -8.476740e-05 -9.248776e-05 -1.008853e-04 -1.100160e-04
## ASV9455      1.028498e-03  1.074748e-03  1.122962e-03  1.173215e-03
## ASV10879     9.375221e-04  9.802513e-04  1.024848e-03  1.071388e-03
## ASV3997      1.200192e-03  1.258037e-03  1.318677e-03  1.382243e-03
## ASV6760      3.641813e-04  3.766778e-04  3.893539e-04  4.021853e-04
## ASV6990      9.701064e-04  1.013063e-03  1.057784e-03  1.104329e-03
## ASV9560      6.218310e-04  6.485517e-04  6.762974e-04  7.050973e-04
## ASV0220     -1.446229e-04 -1.512594e-04 -1.581893e-04 -1.654246e-04
## ASV2518      6.015052e-04  6.293897e-04  6.585314e-04  6.889837e-04
## ASV3615      1.523199e-03  1.592722e-03  1.665284e-03  1.741007e-03
## ASV0075     -4.573779e-06 -4.881924e-06 -5.211949e-06 -5.565395e-06
## ASV8070      7.982209e-05  8.186427e-05  8.385361e-05  8.577581e-05
## ASV1658      6.086194e-04  6.356673e-04  6.638331e-04  6.931561e-04
## ASV0773      1.117738e-03  1.168014e-03  1.220421e-03  1.275039e-03
## ASV0799      1.277913e-04  1.330675e-04  1.385206e-04  1.441523e-04
## ASV1839     -7.710526e-04 -8.061242e-04 -8.427121e-04 -8.808743e-04
## ASV0265      8.915360e-04  9.339940e-04  9.784682e-04  1.025053e-03
## ASV3741      3.276144e-04  3.419452e-04  3.568405e-04  3.723167e-04
## ASV0847      1.232019e-03  1.289205e-03  1.348977e-03  1.411444e-03
## ASV1026      1.620851e-03  1.695255e-03  1.772945e-03  1.854052e-03
## ASV1222     -4.453151e-04 -4.632980e-04 -4.818628e-04 -5.010159e-04
## ASV0729     -2.593972e-05 -2.716551e-05 -2.844890e-05 -2.979257e-05
## ASV0143     -4.112424e-04 -4.296470e-04 -4.488230e-04 -4.687985e-04
## ASV1328      1.952564e-04  2.052575e-04  2.157966e-04  2.269044e-04
## ASV9078     -4.342247e-04 -4.575769e-04 -4.822658e-04 -5.083724e-04
## ASV0027     -4.785770e-04 -5.010699e-04 -5.246034e-04 -5.492241e-04
## ASV0546     -5.628155e-04 -5.877155e-04 -6.136358e-04 -6.406115e-04
## ASV1136      1.347758e-03  1.409893e-03  1.474802e-03  1.542602e-03
## ASV3081      7.068283e-04  7.395965e-04  7.738485e-04  8.096489e-04
## ASV0531      2.057516e-04  2.163457e-04  2.275120e-04  2.392831e-04
## ASV2525      1.058628e-03  1.106339e-03  1.156081e-03  1.207929e-03
## ASV1083     -2.162765e-04 -2.251027e-04 -2.342233e-04 -2.436423e-04
## ASV0424     -1.497401e-04 -1.567878e-04 -1.641625e-04 -1.718792e-04
## ASV0644      5.952970e-05  6.495101e-05  7.084781e-05  7.725932e-05
## ASV6007     -5.938947e-05 -6.481303e-05 -7.071448e-05 -7.713356e-05
## ASV0564      4.959779e-04  5.196473e-04  5.444426e-04  5.704164e-04
## ASV1938      1.587959e-03  1.656838e-03  1.728402e-03  1.802729e-03
## ASV6516     -2.444519e-03 -2.558322e-03 -2.677304e-03 -2.801690e-03
## ASV0503     -9.880817e-04 -1.031261e-03 -1.076155e-03 -1.122814e-03
## ASV6913     -4.892948e-03 -5.116224e-03 -5.349296e-03 -5.592561e-03
## ASV0164     -6.044159e-04 -6.328029e-04 -6.625042e-04 -6.935791e-04
## ASV1576      1.725208e-03  1.804452e-03  1.887216e-03  1.973646e-03
## ASV1725      8.426381e-04  8.834346e-04  9.262170e-04  9.710812e-04
## ASV4501      4.671377e-04  4.865089e-04  5.065495e-04  5.272702e-04
## ASV10678    -2.254588e-03 -2.359216e-03 -2.468572e-03 -2.582860e-03
## ASV0944      3.542948e-04  3.712662e-04  3.890540e-04  4.076977e-04
## ASV2292      1.834003e-03  1.917493e-03  2.004608e-03  2.095492e-03
## ASV1090      7.373384e-04  7.710844e-04  8.063148e-04  8.430898e-04
## ASV9117     -5.221693e-04 -5.436710e-04 -5.659127e-04 -5.889078e-04
## ASV0285     -8.637979e-04 -9.084596e-04 -9.555386e-04 -1.005171e-03
## ASV0463     -5.238979e-04 -5.469097e-04 -5.708433e-04 -5.957278e-04
## ASV3199      6.665339e-04  6.955020e-04  7.256055e-04  7.568782e-04
## ASV0150     -1.014515e-04 -1.068318e-04 -1.125134e-04 -1.185139e-04
## ASV6583     -5.606747e-04 -5.846429e-04 -6.095300e-04 -6.353635e-04
## ASV0392      5.634498e-05  5.869520e-05  6.112739e-05  6.364289e-05
## ASV14007    -8.235220e-04 -8.609688e-04 -9.000351e-04 -9.407834e-04
## ASV0177     -3.882212e-04 -4.057287e-04 -4.239813e-04 -4.430068e-04
## ASV6448     -5.853306e-04 -6.153419e-04 -6.469595e-04 -6.802729e-04
## ASV5399     -3.619045e-03 -3.795482e-03 -3.980641e-03 -4.174960e-03
## ASV0277     -8.612659e-05 -8.997414e-05 -9.398016e-05 -9.814979e-05
## ASV2599      5.048171e-04  5.188824e-04  5.327761e-04  5.464253e-04
## ASV13465    -2.781864e-04 -2.886656e-04 -2.994118e-04 -3.104198e-04
## ASV2412      2.131603e-04  2.230849e-04  2.334612e-04  2.443086e-04
## ASV0423     -8.048355e-05 -8.344733e-05 -8.647323e-05 -8.955730e-05
## ASV5187      1.135507e-03  1.182110e-03  1.230300e-03  1.280103e-03
## ASV0701     -7.259853e-04 -7.599982e-04 -7.955780e-04 -8.327944e-04
## ASV4248      3.900390e-04  4.093745e-04  4.296906e-04  4.510379e-04
## ASV0519      6.839934e-04  7.164646e-04  7.504665e-04  7.860698e-04
## ASV0764      1.804039e-04  1.890776e-04  1.981689e-04  2.076975e-04
## ASV5385     -6.113848e-04 -6.402094e-04 -6.703797e-04 -7.019573e-04
## ASV3021     -1.066857e-03 -1.111805e-03 -1.158399e-03 -1.206681e-03
## ASV4119     -2.717276e-03 -2.842108e-03 -2.972495e-03 -3.108668e-03
## ASV2534     -1.060302e-04 -1.126599e-04 -1.197354e-04 -1.272875e-04
## ASV1061      6.759907e-04  7.095414e-04  7.448074e-04  7.818799e-04
## ASV0670     -1.838246e-04 -1.923928e-04 -2.013513e-04 -2.107171e-04
## ASV1384      7.882711e-04  8.270853e-04  8.678432e-04  9.106430e-04
## ASV1981      1.924031e-03  2.015072e-03  2.110384e-03  2.210164e-03
## ASV9632     -4.147817e-04 -4.301494e-04 -4.458854e-04 -4.619804e-04
## ASV4564      5.677574e-04  5.942222e-04  6.218912e-04  6.508161e-04
## ASV5289     -3.518136e-04 -3.690490e-04 -3.871494e-04 -4.061598e-04
## ASV0516      1.345262e-03  1.407730e-03  1.473021e-03  1.541254e-03
## ASV1463     -1.888179e-03 -1.975611e-03 -2.066977e-03 -2.162444e-03
## ASV0969      7.397937e-05  7.714246e-05  8.042294e-05  8.382343e-05
## ASV1113     -4.303883e-04 -4.504396e-04 -4.714044e-04 -4.933222e-04
## ASV1234     -5.060897e-04 -5.322955e-04 -5.599421e-04 -5.891153e-04
## ASV3814     -2.876439e-04 -3.063773e-04 -3.264184e-04 -3.478602e-04
## ASV1000      8.650769e-04  9.044475e-04  9.455233e-04  9.883703e-04
## ASV0079     -9.052853e-05 -9.528185e-05 -1.002999e-04 -1.055983e-04
## ASV0145      1.641207e-04  1.705550e-04  1.771798e-04  1.839952e-04
## ASV0457     -1.124839e-03 -1.176315e-03 -1.230049e-03 -1.286133e-03
## ASV1485      8.847382e-05  9.277617e-05  9.729155e-05  1.020308e-04
## ASV0535      3.340288e-04  3.509887e-04  3.688423e-04  3.876385e-04
## ASV0259     -6.264871e-04 -6.554245e-04 -6.856545e-04 -7.172307e-04
## ASV0570      1.889962e-04  1.983825e-04  2.082495e-04  2.186227e-04
## ASV0906      7.223510e-04  7.550554e-04  7.891624e-04  8.247253e-04
## ASV1748      7.288656e-04  7.559636e-04  7.836810e-04  8.119912e-04
## ASV5520     -9.258245e-04 -9.728501e-04 -1.022356e-03 -1.074476e-03
## ASV2288     -2.364701e-03 -2.474519e-03 -2.589307e-03 -2.709278e-03
## ASV1887     -4.653921e-04 -4.908565e-04 -5.177930e-04 -5.462890e-04
## ASV0374     -1.022826e-04 -1.064444e-04 -1.107435e-04 -1.151814e-04
## ASV0823      1.393230e-03  1.455722e-03  1.520850e-03  1.588712e-03
## ASV0717      1.028614e-04  1.076809e-04  1.127217e-04  1.179936e-04
## ASV0431     -2.788990e-04 -2.921330e-04 -3.059921e-04 -3.205055e-04
## ASV1030      3.201942e-03  3.353809e-03  3.512837e-03  3.679359e-03
## ASV1082     -4.182533e-04 -4.378878e-04 -4.584300e-04 -4.799206e-04
## ASV2684      5.612144e-05  6.059440e-05  6.542033e-05  7.062512e-05
## ASV0051      3.990425e-04  4.177264e-04  4.372711e-04  4.577150e-04
## ASV0513     -1.271134e-04 -1.327463e-04 -1.386085e-04 -1.447075e-04
## ASV0581      7.286078e-04  7.626179e-04  7.981811e-04  8.353651e-04
## ASV7282      2.262293e-04  2.385295e-04  2.515510e-04  2.653396e-04
## ASV3009     -6.237405e-04 -6.527909e-04 -6.831632e-04 -7.149146e-04
## ASV2106      7.193700e-04  7.568360e-04  7.963569e-04  8.380515e-04
## ASV1012      5.242398e-04  5.491638e-04  5.752626e-04  6.025898e-04
## ASV0921      5.276293e-04  5.530240e-04  5.796523e-04  6.075750e-04
## ASV0010     -3.113835e-04 -3.260216e-04 -3.413375e-04 -3.573616e-04
## ASV1178      1.405081e-04  1.473042e-04  1.544296e-04  1.619001e-04
## ASV2848     -8.402531e-04 -8.785407e-04 -9.185040e-04 -9.602112e-04
## ASV0586      2.068033e-03  2.166171e-03  2.268950e-03  2.376586e-03
## ASV4225     -3.220185e-03 -3.345789e-03 -3.475071e-03 -3.608033e-03
## ASV2156     -1.164225e-03 -1.219089e-03 -1.276510e-03 -1.336606e-03
## ASV9778     -8.381589e-04 -8.773452e-04 -9.183295e-04 -9.611911e-04
## ASV0493     -1.721405e-03 -1.800123e-03 -1.882299e-03 -1.968074e-03
## ASV3770     -1.929967e-04 -2.049010e-04 -2.175961e-04 -2.311361e-04
## ASV0470      1.196021e-03  1.251906e-03  1.310353e-03  1.371476e-03
## ASV0262     -5.014147e-04 -5.266086e-04 -5.531107e-04 -5.809913e-04
## ASV0998      3.111099e-04  3.258083e-04  3.411955e-04  3.573032e-04
## ASV7708     -1.534050e-04 -1.601068e-04 -1.670718e-04 -1.743075e-04
## ASV0453     -1.232866e-04 -1.289749e-04 -1.349202e-04 -1.411339e-04
## ASV0044      5.014193e-04  5.246840e-04  5.489993e-04  5.744099e-04
## ASV5490      2.909256e-04  3.037037e-04  3.169885e-04  3.307946e-04
## ASV2638     -1.707658e-04 -1.779599e-04 -1.854229e-04 -1.931628e-04
## ASV0829      1.729333e-03  1.809667e-03  1.893614e-03  1.981322e-03
## ASV0601      5.719284e-04  5.992490e-04  6.278761e-04  6.578722e-04
## ASV0234      4.294906e-05  4.512027e-05  4.740655e-05  4.981443e-05
## ASV0133      8.762873e-04  9.172613e-04  9.601152e-04  1.004932e-03
## ASV0323      2.854037e-04  2.991543e-04  3.135744e-04  3.286970e-04
## ASV0854     -1.998109e-04 -2.090521e-04 -2.187081e-04 -2.287965e-04
## ASV0110      5.516918e-04  5.775902e-04  6.046870e-04  6.330360e-04
## ASV0816     -5.440692e-05 -5.700437e-05 -5.972570e-05 -6.257679e-05
## ASV1031     -2.084437e-04 -2.176403e-04 -2.272125e-04 -2.371734e-04
## ASV0144     -2.535876e-04 -2.656700e-04 -2.783294e-04 -2.915934e-04
## ASV0020     -1.170895e-04 -1.228393e-04 -1.288794e-04 -1.352251e-04
## ASV0962     -3.287669e-04 -3.440113e-04 -3.599425e-04 -3.765898e-04
## ASV0794      6.057307e-04  6.353863e-04  6.665168e-04  6.991965e-04
## ASV7117     -5.758947e-04 -6.023228e-04 -6.299179e-04 -6.587273e-04
## ASV1008     -2.745980e-04 -2.877771e-04 -3.015921e-04 -3.160739e-04
## ASV0096      7.063502e-04  7.394869e-04  7.741545e-04  8.104217e-04
## ASV0128     -1.159381e-03 -1.214706e-03 -1.272676e-03 -1.333416e-03
## ASV5232      1.063611e-03  1.115078e-03  1.169060e-03  1.225678e-03
## ASV0031     -8.279912e-05 -8.672546e-05 -9.083665e-05 -9.514124e-05
## ASV1744     -1.128001e-03 -1.181326e-03 -1.237165e-03 -1.295637e-03
## ASV0289      3.185941e-04  3.334997e-04  3.490912e-04  3.653992e-04
## ASV7413     -1.734555e-04 -1.833253e-04 -1.938018e-04 -2.049246e-04
## ASV0822     -1.418323e-03 -1.482943e-03 -1.550373e-03 -1.620723e-03
## ASV8111     -2.345354e-03 -2.452004e-03 -2.563300e-03 -2.679431e-03
## ASV0687      3.011797e-04  3.155868e-04  3.306827e-04  3.464998e-04
## ASV0112     -1.098012e-04 -1.150744e-04 -1.206022e-04 -1.263970e-04
## ASV0987      3.720244e-04  3.898571e-04  4.085493e-04  4.281426e-04
## ASV5332     -2.455620e-04 -2.546313e-04 -2.639269e-04 -2.734461e-04
## ASV1129     -6.869119e-04 -7.191314e-04 -7.528411e-04 -7.881081e-04
## ASV1274     -1.902897e-04 -1.991535e-04 -2.084212e-04 -2.181103e-04
## ASV0119      4.582036e-04  4.796761e-04  5.021388e-04  5.256356e-04
## ASV0890     -2.371059e-05 -2.490049e-05 -2.615412e-05 -2.747533e-05
## ASV0848     -8.509429e-04 -8.908066e-04 -9.325073e-04 -9.761272e-04
## ASV5944     -3.753338e-03 -3.926979e-03 -4.108419e-03 -4.297987e-03
## ASV19741    -1.367397e-03 -1.430896e-03 -1.497269e-03 -1.566640e-03
## ASV0504     -1.731644e-03 -1.810576e-03 -1.892950e-03 -1.978903e-03
## ASV2146     -1.256076e-03 -1.312282e-03 -1.370854e-03 -1.431879e-03
## ASV0089     -2.910416e-04 -3.045997e-04 -3.187746e-04 -3.335927e-04
## ASV2301     -4.704601e-04 -4.926662e-04 -5.159103e-04 -5.402401e-04
## ASV2982     -8.471394e-03 -8.822029e-03 -9.184963e-03 -9.560448e-03
## ASV0891     -5.508106e-04 -5.765014e-04 -6.033652e-04 -6.314533e-04
## ASV0093      6.027038e-04  6.306533e-04  6.598649e-04  6.903926e-04
## ASV0042      2.106347e-04  2.205104e-04  2.308420e-04  2.416500e-04
## ASV0980      6.889166e-04  7.198378e-04  7.520572e-04  7.856208e-04
## ASV0069     -3.216515e-04 -3.367279e-04 -3.524988e-04 -3.689952e-04
## ASV1364     -2.477332e-04 -2.591534e-04 -2.710825e-04 -2.835413e-04
## ASV0524     -1.234722e-03 -1.293150e-03 -1.354326e-03 -1.418375e-03
## ASV0435      1.693815e-03  1.773533e-03  1.856959e-03  1.944259e-03
## ASV0517     -3.345045e-04 -3.502055e-04 -3.666327e-04 -3.838188e-04
## ASV3167     -2.381731e-03 -2.500564e-03 -2.625502e-03 -2.756866e-03
## ASV4280     -1.531678e-03 -1.603177e-03 -1.677948e-03 -1.756135e-03
## ASV1158      5.364011e-04  5.631552e-04  5.912705e-04  6.208163e-04
## ASV2214      5.164807e-04  5.397731e-04  5.640701e-04  5.894124e-04
## ASV0544     -8.285358e-04 -8.680089e-04 -9.093620e-04 -9.526847e-04
## ASV5326     -1.152593e-04 -1.208337e-04 -1.266816e-04 -1.328171e-04
## ASV3765     -6.486305e-04 -6.788398e-04 -7.104236e-04 -7.434415e-04
## ASV4646      1.388966e-05  1.267298e-05  1.123997e-05  9.568171e-06
## ASV0090      5.149992e-05  5.369501e-05  5.597096e-05  5.832950e-05
## ASV3680      1.083133e-03  1.131416e-03  1.181700e-03  1.234053e-03
## ASV0111      1.133717e-04  1.185112e-04  1.238716e-04  1.294614e-04
## ASV0768      1.600713e-04  1.678022e-04  1.759113e-04  1.844174e-04
## ASV4862     -9.588542e-05 -9.963301e-05 -1.034823e-04 -1.074311e-04
## ASV1742     -9.488179e-04 -9.922305e-04 -1.037555e-03 -1.084869e-03
## ASV3701     -3.586697e-04 -3.738119e-04 -3.895117e-04 -4.057831e-04
## ASV2386     -1.792686e-03 -1.877618e-03 -1.966541e-03 -2.059638e-03
## ASV0375     -1.276632e-03 -1.335238e-03 -1.396444e-03 -1.460357e-03
## ASV2796      4.442294e-04  4.638075e-04  4.841846e-04  5.053885e-04
## ASV1369      9.925659e-04  1.037104e-03  1.083543e-03  1.131957e-03
## ASV10272    -1.439690e-03 -1.506592e-03 -1.576522e-03 -1.649609e-03
## ASV10354    -2.143975e-03 -2.243596e-03 -2.347725e-03 -2.456555e-03
## ASV1067      7.035867e-04  7.360045e-04  7.698677e-04  8.052366e-04
## ASV1900      1.149814e-03  1.203914e-03  1.260528e-03  1.319770e-03
## ASV4079     -5.193224e-04 -5.449159e-04 -5.717999e-04 -6.000411e-04
## ASV4149      2.280242e-03  2.382674e-03  2.489423e-03  2.600645e-03
## ASV5140     -2.143861e-03 -2.243471e-03 -2.347589e-03 -2.456405e-03
## ASV10782     6.785204e-05  7.232112e-05  7.711977e-05  8.227447e-05
## ASV4273     -2.090576e-04 -2.176216e-04 -2.264612e-04 -2.355773e-04
## ASV8121      9.642948e-04  1.009332e-03  1.056433e-03  1.105690e-03
## ASV8438     -2.439067e-03 -2.552387e-03 -2.670833e-03 -2.794625e-03
## ASV9390     -2.438871e-03 -2.552172e-03 -2.670598e-03 -2.794368e-03
## ASV1340      1.961754e-03  2.054065e-03  2.150665e-03  2.251747e-03
## ASV2650     -4.537353e-03 -4.747047e-03 -4.966126e-03 -5.194982e-03
## ASV4674      1.210944e-03  1.266945e-03  1.325456e-03  1.386583e-03
## ASV10492     2.135326e-05  2.187102e-05  2.236704e-05  2.283608e-05
## ASV11430    -1.861111e-03 -1.947562e-03 -2.037922e-03 -2.132358e-03
## ASV12135    -1.860961e-03 -1.947398e-03 -2.037742e-03 -2.132162e-03
## ASV14970    -2.288476e-03 -2.394761e-03 -2.505850e-03 -2.621949e-03
## ASV1954      2.779277e-03  2.908676e-03  3.043957e-03  3.185376e-03
## ASV2613      1.759189e-03  1.840689e-03  1.925858e-03  2.014851e-03
## ASV2757      1.097773e-03  1.147168e-03  1.198653e-03  1.252305e-03
## ASV2909     -3.261558e-03 -3.416119e-03 -3.577965e-03 -3.747435e-03
## ASV2954     -1.229531e-04 -1.287033e-04 -1.347163e-04 -1.410033e-04
## ASV2969      8.346321e-04  8.739685e-04  9.151390e-04  9.582273e-04
## ASV3410      2.949890e-04  3.090908e-04  3.238699e-04  3.393592e-04
## ASV3575      5.681793e-04  5.942345e-04  6.214407e-04  6.498450e-04
## ASV4275      1.459582e-03  1.525769e-03  1.594804e-03  1.666792e-03
## ASV4652      3.119100e-04  3.267428e-04  3.422796e-04  3.585537e-04
## ASV4761      1.058328e-03  1.106233e-03  1.156188e-03  1.208269e-03
## ASV6003      7.687101e-04  8.055892e-04  8.442493e-04  8.847774e-04
## ASV6110     -5.251102e-03 -5.495023e-03 -5.749976e-03 -6.016429e-03
## ASV7427      9.139966e-04  9.559047e-04  9.996594e-04  1.045335e-03
## ASV8092     -1.721952e-03 -1.801935e-03 -1.885534e-03 -1.972904e-03
## ASV8169     -5.250403e-03 -5.494258e-03 -5.749137e-03 -6.015511e-03
## ASV9693      8.914608e-04  9.327022e-04  9.757938e-04  1.020813e-03
## ASV10913     5.970779e-04  6.252532e-04  6.547456e-04  6.856154e-04
## ASV1979      5.304713e-04  5.547160e-04  5.800196e-04  6.064236e-04
## ASV3772      1.096193e-03  1.146215e-03  1.198419e-03  1.252892e-03
## ASV0113     -1.463926e-04 -1.533001e-04 -1.605298e-04 -1.680964e-04
## ASV1800     -1.932169e-04 -2.023911e-04 -2.119967e-04 -2.220534e-04
## ASV2335     -4.039960e-03 -4.225488e-03 -4.419257e-03 -4.621612e-03
## ASV0692     -2.705662e-05 -2.837804e-05 -2.976609e-05 -3.122438e-05
## ASV1120      1.450195e-04  1.519226e-04  1.591541e-04  1.667298e-04
## ASV1434     -7.221633e-04 -7.560434e-04 -7.914890e-04 -8.285701e-04
## ASV0076     -3.384884e-04 -3.543381e-04 -3.709165e-04 -3.882560e-04
## ASV0361      1.207759e-03  1.264578e-03  1.324036e-03  1.386254e-03
## ASV2231     -3.859714e-04 -4.050152e-04 -4.250258e-04 -4.460541e-04
## ASV2018     -9.709658e-05 -1.016406e-04 -1.063940e-04 -1.113662e-04
## ASV1529      5.222153e-04  5.471064e-04  5.731844e-04  6.005057e-04
## ASV0841     -1.829624e-04 -1.914535e-04 -2.003284e-04 -2.096034e-04
## ASV2556     -3.354083e-03 -3.510858e-03 -3.674818e-03 -3.846279e-03
## ASV2777      1.119785e-03  1.169258e-03  1.220736e-03  1.274284e-03
## ASV0355      8.359993e-04  8.749854e-04  9.157514e-04  9.583753e-04
## ASV5169     -1.000239e-03 -1.046758e-03 -1.095387e-03 -1.146216e-03
## ASV3091      9.400230e-04  9.845071e-04  1.031083e-03  1.079848e-03
## ASV2435      3.811463e-04  3.988164e-04  4.172826e-04  4.365785e-04
## ASV6822     -2.062137e-03 -2.157944e-03 -2.258086e-03 -2.362748e-03
## ASV12605    -2.004597e-03 -2.098792e-03 -2.197351e-03 -2.300471e-03
## ASV0286     -4.821866e-04 -5.046125e-04 -5.280605e-04 -5.525754e-04
## ASV0074     -1.901266e-04 -1.990967e-04 -2.084854e-04 -2.183115e-04
## ASV2485     -7.838080e-05 -8.252830e-05 -8.691557e-05 -9.155834e-05
## ASV1233     -1.505100e-03 -1.575891e-03 -1.649971e-03 -1.727492e-03
## ASV0356     -4.001639e-04 -4.185832e-04 -4.378235e-04 -4.579191e-04
## ASV2918     -1.679803e-03 -1.757806e-03 -1.839339e-03 -1.924555e-03
## ASV1427     -2.088848e-04 -2.190157e-04 -2.296467e-04 -2.408034e-04
## ASV1409      3.689611e-04  3.865537e-04  4.049858e-04  4.242974e-04
## ASV0770      1.169116e-04  1.221651e-04  1.276396e-04  1.333430e-04
## ASV1403     -1.033927e-03 -1.082119e-03 -1.132509e-03 -1.185191e-03
## ASV0314     -3.594424e-04 -3.759094e-04 -3.930986e-04 -4.110387e-04
## ASV0187     -1.047906e-04 -1.098122e-04 -1.150739e-04 -1.205870e-04
## ASV0313     -5.101157e-04 -5.336553e-04 -5.582451e-04 -5.839289e-04
## ASV1087      1.173464e-03  1.228251e-03  1.285544e-03  1.345454e-03
## ASV1970     -1.785478e-04 -1.868452e-04 -1.955177e-04 -2.045813e-04
## ASV0754      1.290725e-03  1.351243e-03  1.414553e-03  1.480781e-03
## ASV3775     -3.081418e-04 -3.226908e-04 -3.379207e-04 -3.538628e-04
## ASV0132     -2.226500e-04 -2.330670e-04 -2.439625e-04 -2.553579e-04
## ASV2329      1.307471e-04  1.346705e-04  1.385847e-04  1.424739e-04
## ASV0561      3.306902e-04  3.455974e-04  3.611344e-04  3.773236e-04
## ASV0130     -6.725208e-04 -7.040524e-04 -7.370380e-04 -7.715421e-04
## ASV0226      8.485174e-04  8.880319e-04  9.293437e-04  9.725305e-04
## ASV12648    -1.192980e-03 -1.247781e-03 -1.305018e-03 -1.364792e-03
## ASV0204      8.165423e-04  8.545737e-04  8.943356e-04  9.359028e-04
## ASV0767     -3.931361e-04 -4.121845e-04 -4.321708e-04 -4.531424e-04
## ASV0335     -7.605625e-04 -7.958936e-04 -8.328227e-04 -8.714178e-04
## ASV5901     -1.677148e-04 -1.752107e-04 -1.830224e-04 -1.911619e-04
## ASV0596     -1.901184e-06 -1.493686e-06 -1.020848e-06 -4.754542e-07
## ASV9271      6.068021e-04  6.371657e-04  6.690927e-04  7.026654e-04
## ASV0904      4.910355e-04  5.143501e-04  5.387678e-04  5.643403e-04
## ASV15270    -3.172410e-04 -3.334329e-04 -3.504820e-04 -3.684348e-04
## ASV0990     -2.716259e-04 -2.844566e-04 -2.978885e-04 -3.119492e-04
## ASV0155     -5.649202e-04 -5.912973e-04 -6.188808e-04 -6.477236e-04
## ASV0086     -1.126459e-04 -1.179193e-04 -1.234351e-04 -1.292042e-04
## ASV2581     -5.498239e-05 -5.739174e-05 -5.989554e-05 -6.249632e-05
## ASV1579     -4.604240e-04 -4.823628e-04 -5.053461e-04 -5.294236e-04
## ASV7730     -2.265349e-05 -2.465844e-05 -2.683079e-05 -2.918313e-05
## ASV0897      6.876500e-05  7.210601e-05  7.561201e-05  7.929136e-05
## ASV1975      3.162735e-03  3.310551e-03  3.465149e-03  3.626830e-03
##                                                                    
## (Intercept)  1.179699e-02  1.234733e-02  1.292275e-02  1.352434e-02
## ASV1236      1.909319e-03  1.995940e-03  2.086286e-03  2.180498e-03
## ASV0421     -9.035379e-04 -9.442107e-04 -9.866052e-04 -1.030784e-03
## ASV0691     -1.852806e-03 -1.933585e-03 -2.017541e-03 -2.104769e-03
## ASV0899      1.111921e-03  1.164158e-03  1.218804e-03  1.275966e-03
## ASV1004      4.301019e-03  4.496770e-03  4.701002e-03  4.914044e-03
## ASV1041     -2.629304e-03 -2.749819e-03 -2.875627e-03 -3.006939e-03
## ASV1058      2.680000e-03  2.802008e-03  2.929309e-03  3.062109e-03
## ASV12542     1.011380e-03  1.056732e-03  1.103993e-03  1.153229e-03
## ASV1294      2.254069e-03  2.357068e-03  2.464570e-03  2.576751e-03
## ASV13113     8.004043e-04  8.386661e-04  8.787642e-04  9.207875e-04
## ASV1318      2.468340e-03  2.580962e-03  2.698489e-03  2.821112e-03
## ASV2269     -4.192092e-03 -4.384605e-03 -4.585588e-03 -4.795375e-03
## ASV2542      1.847394e-03  1.934117e-03  2.024848e-03  2.119768e-03
## ASV2660     -1.865529e-03 -1.950424e-03 -2.038991e-03 -2.131370e-03
## ASV2737      3.456426e-04  3.602341e-04  3.753594e-04  3.910310e-04
## ASV2840      2.342433e-03  2.447875e-03  2.557775e-03  2.672295e-03
## ASV3053      1.973888e-02  2.063286e-02  2.156522e-02  2.253740e-02
## ASV3077      6.954883e-04  7.268988e-04  7.596528e-04  7.938012e-04
## ASV3134      1.330777e-03  1.393750e-03  1.459685e-03  1.528720e-03
## ASV3140      1.622328e-03  1.697942e-03  1.776992e-03  1.859625e-03
## ASV3579      5.289982e-04  5.545157e-04  5.812800e-04  6.093532e-04
## ASV6119     -1.144139e-03 -1.196674e-03 -1.251520e-03 -1.308768e-03
## ASV7557     -2.327376e-03 -2.434232e-03 -2.545786e-03 -2.662224e-03
## ASV8422      5.133129e-04  5.359395e-04  5.594851e-04  5.839807e-04
## ASV1086     -1.225346e-04 -1.278264e-04 -1.333254e-04 -1.390379e-04
## ASV1310      9.929684e-04  1.038148e-03  1.085283e-03  1.134452e-03
## ASV15750    -1.703284e-04 -1.780281e-04 -1.860523e-04 -1.944121e-04
## ASV16905    -4.777974e-04 -4.997338e-04 -5.226346e-04 -5.465381e-04
## ASV2033      2.100662e-03  2.198817e-03  2.301469e-03  2.408817e-03
## ASV2089      8.734282e-04  9.136355e-04  9.556188e-04  9.994490e-04
## ASV2127      3.305350e-03  3.455671e-03  3.612497e-03  3.776079e-03
## ASV2725      2.650368e-03  2.769696e-03  2.894077e-03  3.023696e-03
## ASV2804     -9.895277e-04 -1.034956e-03 -1.082382e-03 -1.131885e-03
## ASV3075      2.220077e-03  2.321631e-03  2.427645e-03  2.538299e-03
## ASV3327      3.022874e-03  3.163859e-03  3.311284e-03  3.465432e-03
## ASV3342      2.490812e-03  2.606582e-03  2.727590e-03  2.854060e-03
## ASV3532     -2.833972e-03 -2.966019e-03 -3.104066e-03 -3.248373e-03
## ASV3600      1.278938e-03  1.337923e-03  1.399542e-03  1.463903e-03
## ASV4013      2.473026e-03  2.586064e-03  2.704049e-03  2.827177e-03
## ASV4136      2.723350e-03  2.846111e-03  2.974080e-03  3.107450e-03
## ASV4195      1.000211e-02  1.046125e-02  1.094056e-02  1.144086e-02
## ASV4407     -3.912383e-03 -4.091959e-03 -4.279425e-03 -4.475095e-03
## ASV4717      3.864597e-04  4.020112e-04  4.180624e-04  4.346186e-04
## ASV6794      1.541454e-03  1.609253e-03  1.679786e-03  1.753140e-03
## ASV8324     -2.004100e-03 -2.096085e-03 -2.192112e-03 -2.292340e-03
## ASV8981     -7.014695e-05 -7.304178e-05 -7.603041e-05 -7.911302e-05
## ASV9859      6.057641e-04  6.354949e-04  6.667272e-04  6.995407e-04
## ASV0936      1.551541e-04  1.631099e-04  1.714851e-04  1.803020e-04
## ASV12683    -4.802239e-05 -5.067882e-05 -5.348825e-05 -5.645941e-05
## ASV1293      1.261825e-03  1.319121e-03  1.378886e-03  1.441215e-03
## ASV13055    -6.871192e-05 -7.160202e-05 -7.458860e-05 -7.767191e-05
## ASV17063    -1.038877e-03 -1.086547e-03 -1.136311e-03 -1.188251e-03
## ASV2228      8.457636e-04  8.845685e-04  9.250771e-04  9.673569e-04
## ASV2769      8.423351e-05  8.829951e-05  9.256731e-05  9.704755e-05
## ASV2803      7.558312e-04  7.890422e-04  8.235890e-04  8.595145e-04
## ASV2896      7.033843e-04  7.360370e-04  7.701713e-04  8.058518e-04
## ASV3062      7.552284e-04  7.910797e-04  8.286312e-04  8.679634e-04
## ASV3107      1.408826e-03  1.474397e-03  1.542952e-03  1.614621e-03
## ASV3265      1.947339e-03  2.035740e-03  2.127951e-03  2.224117e-03
## ASV3666      7.305077e-06  7.506274e-06  7.707918e-06  7.909709e-06
## ASV4497      5.923877e-04  6.193954e-04  6.475824e-04  6.769959e-04
## ASV6914     -1.402810e-04 -1.472129e-04 -1.544921e-04 -1.621361e-04
## ASV0576     -2.510768e-03 -2.622028e-03 -2.737838e-03 -2.858349e-03
## ASV0673      1.854444e-03  1.940519e-03  2.030482e-03  2.124495e-03
## ASV0772      1.072384e-03  1.121451e-03  1.172675e-03  1.226143e-03
## ASV0862     -1.766653e-04 -1.834879e-04 -1.904976e-04 -1.976922e-04
## ASV0898      7.784163e-04  8.152416e-04  8.537916e-04  8.941447e-04
## ASV0910      9.628259e-04  1.007874e-03  1.054991e-03  1.104271e-03
## ASV0964     -9.988318e-04 -1.043773e-03 -1.090621e-03 -1.139445e-03
## ASV10059     6.810538e-04  7.135719e-04  7.476496e-04  7.833622e-04
## ASV10263    -1.582696e-03 -1.655358e-03 -1.731214e-03 -1.810392e-03
## ASV1088      1.549232e-03  1.621476e-03  1.697024e-03  1.776021e-03
## ASV1101      1.842529e-03  1.926423e-03  2.013954e-03  2.105265e-03
## ASV1183      5.580742e-04  5.841012e-04  6.113122e-04  6.397583e-04
## ASV11956     4.962373e-04  5.174547e-04  5.394735e-04  5.623148e-04
## ASV12774    -6.774222e-06 -7.694870e-06 -8.708856e-06 -9.824367e-06
## ASV1321      2.398375e-03  2.510720e-03  2.628243e-03  2.751175e-03
## ASV13793    -1.090752e-03 -1.140825e-03 -1.193099e-03 -1.247661e-03
## ASV14482     1.377335e-05  1.373303e-05  1.363484e-05  1.347210e-05
## ASV15483     4.032423e-04  4.220214e-04  4.416587e-04  4.621922e-04
## ASV2062      2.018151e-03  2.110787e-03  2.207512e-03  2.308493e-03
## ASV2132      1.751451e-03  1.833300e-03  1.918903e-03  2.008427e-03
## ASV2413      1.593306e-03  1.665549e-03  1.740901e-03  1.819483e-03
## ASV2490      4.952268e-03  5.173537e-03  5.404014e-03  5.644022e-03
## ASV2594      5.738286e-04  6.001242e-04  6.275830e-04  6.562532e-04
## ASV2822     -2.882797e-03 -3.015161e-03 -3.153346e-03 -3.297583e-03
## ASV2863      3.129877e-03  3.271282e-03  3.418714e-03  3.572396e-03
## ASV2910      1.085310e-03  1.134331e-03  1.185444e-03  1.238728e-03
## ASV2980      1.048283e-03  1.096568e-03  1.146993e-03  1.199644e-03
## ASV3307      2.283323e-03  2.388142e-03  2.497570e-03  2.611787e-03
## ASV3474      1.379888e-03  1.444780e-03  1.512685e-03  1.583741e-03
## ASV3502      1.671651e-03  1.748845e-03  1.829491e-03  1.913736e-03
## ASV4236      2.439934e-03  2.549980e-03  2.664704e-03  2.784281e-03
## ASV4842     -4.716442e-04 -4.945218e-04 -5.185073e-04 -5.436527e-04
## ASV4894     -1.090880e-03 -1.140965e-03 -1.193252e-03 -1.247829e-03
## ASV5290      8.657777e-04  9.057842e-04  9.475856e-04  9.912577e-04
## ASV5501      4.329648e-04  4.528538e-04  4.736302e-04  4.953317e-04
## ASV5795      5.292328e-04  5.537225e-04  5.793153e-04  6.060583e-04
## ASV5987     -3.052187e-03 -3.192330e-03 -3.338635e-03 -3.491348e-03
## ASV6267     -3.440269e-03 -3.598215e-03 -3.763105e-03 -3.935215e-03
## ASV6862      1.416232e-03  1.479341e-03  1.545066e-03  1.613496e-03
## ASV7145      5.355418e-04  5.584418e-04  5.822081e-04  6.068639e-04
## ASV7673     -1.090817e-03 -1.140896e-03 -1.193177e-03 -1.247746e-03
## ASV7789      4.548664e-04  4.767798e-04  4.997628e-04  5.238692e-04
## ASV7809     -2.231555e-05 -2.306056e-05 -2.380790e-05 -2.455430e-05
## ASV8002     -1.377983e-03 -1.441243e-03 -1.507284e-03 -1.576216e-03
## ASV8205      4.646206e-04  4.857903e-04  5.078865e-04  5.309468e-04
## ASV9155     -3.793461e-04 -3.966580e-04 -4.147190e-04 -4.335573e-04
## ASV9221      3.440925e-05  3.583797e-05  3.731936e-05  3.885498e-05
## ASV9311     -2.212084e-03 -2.313625e-03 -2.419629e-03 -2.530273e-03
## ASV9557     -1.510805e-03 -1.580149e-03 -1.652539e-03 -1.728098e-03
## ASV9936     -3.050798e-03 -3.190810e-03 -3.336974e-03 -3.489532e-03
## ASV1445      1.995227e-03  2.087675e-03  2.184289e-03  2.285245e-03
## ASV4232      8.811464e-04  9.226420e-04  9.660736e-04  1.011530e-03
## ASV6479      1.293165e-04  1.367132e-04  1.445806e-04  1.529524e-04
## ASV0142     -1.266982e-03 -1.324160e-03 -1.383774e-03 -1.445913e-03
## ASV0378     -5.747770e-05 -5.925529e-05 -6.102972e-05 -6.279302e-05
## ASV1122      1.962496e-03  2.053682e-03  2.148999e-03  2.248627e-03
## ASV0123     -1.121371e-03 -1.171925e-03 -1.224626e-03 -1.279555e-03
## ASV2064      6.454735e-04  6.738017e-04  7.032722e-04  7.339226e-04
## ASV4459     -2.824944e-04 -2.958517e-04 -3.098297e-04 -3.244560e-04
## ASV0448      4.216489e-04  4.418795e-04  4.630838e-04  4.853086e-04
## ASV0397      9.122509e-04  9.545029e-04  9.986542e-04  1.044785e-03
## ASV0485      1.198506e-03  1.253329e-03  1.310554e-03  1.370277e-03
## ASV1566      1.900024e-03  1.987563e-03  2.079000e-03  2.174494e-03
## ASV1365      1.217549e-03  1.273193e-03  1.331273e-03  1.391885e-03
## ASV1065      2.279808e-03  2.385284e-03  2.495493e-03  2.610634e-03
## ASV0722     -1.313162e-04 -1.374320e-04 -1.438298e-04 -1.505228e-04
## ASV12660    -1.255832e-03 -1.312728e-03 -1.372062e-03 -1.433924e-03
## ASV0223      1.916125e-04  2.004639e-04  2.097102e-04  2.193674e-04
## ASV0229      4.740050e-04  4.962362e-04  5.194919e-04  5.438177e-04
## ASV0877      4.730392e-05  4.883117e-05  5.037387e-05  5.192878e-05
## ASV0983      1.215686e-03  1.270979e-03  1.328662e-03  1.388828e-03
## ASV0626     -9.566884e-05 -9.886881e-05 -1.020979e-04 -1.053468e-04
## ASV4146     -6.596655e-05 -6.929996e-05 -7.280710e-05 -7.649733e-05
## ASV4175     -1.458915e-03 -1.526662e-03 -1.597467e-03 -1.671461e-03
## ASV2082     -6.783313e-04 -7.113571e-04 -7.460273e-04 -7.824273e-04
## ASV2272      6.646869e-04  6.951563e-04  7.269702e-04  7.601836e-04
## ASV2245     -1.062431e-03 -1.111836e-03 -1.163477e-03 -1.217450e-03
## ASV0590     -8.733976e-04 -9.160367e-04 -9.608052e-04 -1.007814e-03
## ASV0217     -1.182305e-04 -1.219659e-04 -1.257095e-04 -1.294473e-04
## ASV0416      8.357638e-04  8.726238e-04  9.109682e-04  9.508436e-04
## ASV1056      9.411860e-04  9.854915e-04  1.031858e-03  1.080380e-03
## ASV7777     -1.418428e-03 -1.484811e-03 -1.554243e-03 -1.626857e-03
## ASV0455      1.804713e-04  1.887964e-04  1.974905e-04  2.065685e-04
## ASV0604      5.703170e-04  5.976093e-04  6.262117e-04  6.561870e-04
## ASV6100     -1.005887e-03 -1.053017e-03 -1.102317e-03 -1.153881e-03
## ASV11359    -2.256394e-03 -2.360363e-03 -2.468947e-03 -2.582335e-03
## ASV6604      4.034604e-04  4.224951e-04  4.424203e-04  4.632771e-04
## ASV5004     -6.414732e-04 -6.713808e-04 -7.026497e-04 -7.353388e-04
## ASV1483     -4.030838e-04 -4.220577e-04 -4.419108e-04 -4.626823e-04
## ASV9773     -1.004728e-03 -1.051573e-03 -1.100554e-03 -1.151761e-03
## ASV4059      7.373597e-04  7.729653e-04  8.103130e-04  8.494901e-04
## ASV1193      1.225282e-03  1.281730e-03  1.340690e-03  1.402267e-03
## ASV4610     -1.737399e-04 -1.805143e-04 -1.874739e-04 -1.946155e-04
## ASV0742     -2.806956e-04 -2.923828e-04 -3.044737e-04 -3.169744e-04
## ASV1502      3.489912e-05  3.564452e-05  3.634511e-05  3.699215e-05
## ASV0195     -4.181643e-05 -4.416519e-05 -4.665876e-05 -4.930692e-05
## ASV1213      1.054203e-03  1.101582e-03  1.150956e-03  1.202396e-03
## ASV1648     -9.423948e-04 -9.864869e-04 -1.032603e-03 -1.080832e-03
## ASV6984     -8.776880e-04 -9.187314e-04 -9.616558e-04 -1.006544e-03
## ASV0396     -1.040253e-04 -1.074434e-04 -1.108904e-04 -1.143571e-04
## ASV4297      1.478998e-03  1.545546e-03  1.614912e-03  1.687200e-03
## ASV2622      1.941612e-03  2.029692e-03  2.121567e-03  2.217380e-03
## ASV3512      6.611781e-04  6.927868e-04  7.259130e-04  7.606300e-04
## ASV2411      1.178532e-03  1.233851e-03  1.291724e-03  1.352266e-03
## ASV2291     -6.129887e-04 -6.433190e-04 -6.752021e-04 -7.087220e-04
## ASV0807      1.359198e-03  1.423265e-03  1.490312e-03  1.560472e-03
## ASV1292      4.566337e-04  4.771852e-04  4.986040e-04  5.209212e-04
## ASV1035      1.309096e-03  1.368166e-03  1.429746e-03  1.493930e-03
## ASV0070     -4.863008e-05 -5.036260e-05 -5.212504e-05 -5.391429e-05
## ASV0255      1.252419e-04  1.306689e-04  1.363027e-04  1.421481e-04
## ASV0057     -4.856786e-04 -5.073053e-04 -5.298249e-04 -5.532679e-04
## ASV0077     -8.451199e-05 -8.800256e-05 -9.161148e-05 -9.534029e-05
## ASV0625      9.471978e-04  9.898124e-04  1.034226e-03  1.080505e-03
## ASV2464      6.330255e-03  6.615310e-03  6.912423e-03  7.222031e-03
## ASV1315      1.864644e-03  1.951116e-03  2.041502e-03  2.135971e-03
## ASV2673      1.589004e-03  1.664146e-03  1.742815e-03  1.825176e-03
## ASV2161      6.833494e-04  7.155480e-04  7.492496e-04  7.845232e-04
## ASV0337     -3.676772e-04 -3.847630e-04 -4.026239e-04 -4.212936e-04
## ASV7680     -2.287121e-03 -2.394111e-03 -2.506010e-03 -2.623034e-03
## ASV0611      1.198200e-03  1.254252e-03  1.312880e-03  1.374195e-03
## ASV3118     -1.418413e-03 -1.485506e-03 -1.555743e-03 -1.629269e-03
## ASV1284      9.125384e-04  9.553767e-04  1.000162e-03  1.046973e-03
## ASV0889      8.752329e-04  9.149953e-04  9.564786e-04  9.997498e-04
## ASV4649     -4.861472e-04 -5.087280e-04 -5.323296e-04 -5.569953e-04
## ASV1108     -1.093196e-03 -1.145347e-03 -1.199984e-03 -1.257227e-03
## ASV0738      2.378708e-04  2.511490e-04  2.652344e-04  2.801804e-04
## ASV0473     -1.005825e-04 -1.057810e-04 -1.112651e-04 -1.170518e-04
## ASV0598     -6.550629e-04 -6.845035e-04 -7.151874e-04 -7.471602e-04
## ASV0429      9.339638e-04  9.765292e-04  1.020943e-03  1.067277e-03
## ASV1549      1.205913e-03  1.263120e-03  1.323028e-03  1.385763e-03
## ASV1203      1.022823e-03  1.069450e-03  1.118105e-03  1.168866e-03
## ASV4532      1.653084e-05  1.682196e-05  1.708433e-05  1.731318e-05
## ASV0274     -1.618716e-04 -1.684712e-04 -1.752894e-04 -1.823287e-04
## ASV0163     -8.602321e-04 -8.988456e-04 -9.390838e-04 -9.810051e-04
## ASV1298      3.536761e-04  3.693833e-04  3.857362e-04  4.027569e-04
## ASV9424     -1.971349e-03 -2.063824e-03 -2.160567e-03 -2.261771e-03
## ASV0412      1.709221e-03  1.787262e-03  1.868709e-03  1.953694e-03
## ASV0284      4.301665e-04  4.489898e-04  4.685568e-04  4.888895e-04
## ASV0620     -4.497166e-04 -4.718743e-04 -4.951513e-04 -5.196061e-04
## ASV0153     -1.363202e-03 -1.427672e-03 -1.495170e-03 -1.565834e-03
## ASV0498      5.211073e-04  5.460496e-04  5.721829e-04  5.995631e-04
## ASV0097      3.528394e-04  3.694821e-04  3.869027e-04  4.051371e-04
## ASV0104     -2.358392e-03 -2.466855e-03 -2.580132e-03 -2.698421e-03
## ASV1282      6.199292e-04  6.487409e-04  6.788474e-04  7.103018e-04
## ASV3883     -6.952228e-04 -7.284504e-04 -7.632656e-04 -7.997437e-04
## ASV0801      4.442252e-04  4.654867e-04  4.877666e-04  5.111134e-04
## ASV1611     -1.609445e-03 -1.685008e-03 -1.764064e-03 -1.846771e-03
## ASV0227     -3.387758e-04 -3.552736e-04 -3.725890e-04 -3.907635e-04
## ASV0833      4.639590e-04  4.856694e-04  5.083771e-04  5.321260e-04
## ASV0718      2.274323e-03  2.380004e-03  2.490472e-03  2.605931e-03
## ASV1139      3.198034e-04  3.333050e-04  3.472903e-04  3.617680e-04
## ASV0766     -3.891969e-04 -4.077997e-04 -4.272930e-04 -4.477194e-04
## ASV2091      2.385867e-03  2.492775e-03  2.604169e-03  2.720209e-03
## ASV1238     -8.539198e-04 -8.905238e-04 -9.285365e-04 -9.680005e-04
## ASV9193     -2.866373e-04 -3.033409e-04 -3.210840e-04 -3.399331e-04
## ASV0290      4.745111e-05  4.907640e-05  5.072339e-05  5.238853e-05
## ASV0231      7.474684e-04  7.816526e-04  8.173332e-04  8.545695e-04
## ASV0185      2.732613e-04  2.873850e-04  3.022791e-04  3.179884e-04
## ASV2330      6.987099e-04  7.297924e-04  7.621539e-04  7.958377e-04
## ASV3119     -3.780519e-04 -3.968382e-04 -4.165882e-04 -4.373538e-04
## ASV2368     -1.000134e-03 -1.047622e-03 -1.097356e-03 -1.149443e-03
## ASV0122     -3.350175e-04 -3.501368e-04 -3.659011e-04 -3.823347e-04
## ASV1044      1.073104e-03  1.124203e-03  1.177733e-03  1.233808e-03
## ASV0160     -5.656865e-04 -5.907178e-04 -6.167699e-04 -6.438765e-04
## ASV0326      1.599724e-04  1.673627e-04  1.750839e-04  1.831497e-04
## ASV1388      2.805059e-03  2.933901e-03  3.068441e-03  3.208911e-03
## ASV0792      1.705682e-03  1.783248e-03  1.864168e-03  1.948573e-03
## ASV0036     -4.419566e-04 -4.627990e-04 -4.846144e-04 -5.074472e-04
## ASV2125      1.554771e-03  1.626026e-03  1.700416e-03  1.778069e-03
## ASV1075      7.294154e-05  7.642438e-05  8.007468e-05  8.390064e-05
## ASV0390      8.253409e-04  8.649170e-04  9.064009e-04  9.498853e-04
## ASV3790     -1.269678e-03 -1.328622e-03 -1.390233e-03 -1.454627e-03
## ASV1535     -2.237788e-04 -2.355307e-04 -2.479347e-04 -2.610288e-04
## ASV0263      1.154084e-03  1.207332e-03  1.262953e-03  1.321045e-03
## ASV0675      2.206936e-03  2.310781e-03  2.419446e-03  2.533148e-03
## ASV3348      2.316050e-04  2.428172e-04  2.545804e-04  2.669226e-04
## ASV0058     -7.483121e-04 -7.822535e-04 -8.176581e-04 -8.545821e-04
## ASV4142      8.972680e-04  9.380773e-04  9.806540e-04  1.025067e-03
## ASV0059     -6.199743e-04 -6.479660e-04 -6.771523e-04 -7.075781e-04
## ASV0013     -8.485389e-04 -8.876900e-04 -9.285902e-04 -9.713128e-04
## ASV0033     -4.206025e-04 -4.404636e-04 -4.612542e-04 -4.830171e-04
## ASV4354     -5.666132e-04 -5.929159e-04 -6.204085e-04 -6.491420e-04
## ASV0022     -3.321399e-04 -3.478520e-04 -3.643021e-04 -3.815243e-04
## ASV0134     -3.587182e-04 -3.758771e-04 -3.938601e-04 -4.127071e-04
## ASV0415      2.929128e-05  3.161250e-05  3.412318e-05  3.683851e-05
## ASV10103    -1.997839e-03 -2.091556e-03 -2.189598e-03 -2.292158e-03
## ASV1613      1.551751e-03  1.622114e-03  1.695500e-03  1.772027e-03
## ASV0135     -2.552391e-04 -2.664574e-04 -2.781233e-04 -2.902503e-04
## ASV0469     -1.959920e-03 -2.049042e-03 -2.142024e-03 -2.239016e-03
## ASV0471      1.421732e-03  1.488287e-03  1.557894e-03  1.630684e-03
## ASV0451     -2.049664e-04 -2.154281e-04 -2.264525e-04 -2.380719e-04
## ASV0747      4.966894e-04  5.202510e-04  5.449218e-04  5.707530e-04
## ASV1314     -6.200113e-04 -6.496352e-04 -6.806776e-04 -7.132065e-04
## ASV0425     -2.822478e-03 -2.948810e-03 -3.080434e-03 -3.217539e-03
## ASV0559     -7.965552e-04 -8.327297e-04 -8.704707e-04 -9.098397e-04
## ASV0148     -4.514026e-04 -4.711947e-04 -4.917756e-04 -5.131696e-04
## ASV0129     -1.465252e-04 -1.516974e-04 -1.569568e-04 -1.622943e-04
## ASV1072      3.183696e-04  3.321946e-04  3.465604e-04  3.614832e-04
## ASV2390      1.071802e-03  1.119552e-03  1.169272e-03  1.221031e-03
## ASV0548      9.348548e-04  9.780051e-04  1.023086e-03  1.070178e-03
## ASV0168     -6.320656e-04 -6.607577e-04 -6.906890e-04 -7.219074e-04
## ASV0066     -5.171542e-04 -5.409762e-04 -5.658579e-04 -5.918429e-04
## ASV0468     -3.335996e-04 -3.490914e-04 -3.652841e-04 -3.822078e-04
## ASV0172     -1.618339e-04 -1.685964e-04 -1.755972e-04 -1.828405e-04
## ASV0236     -3.063617e-04 -3.182632e-04 -3.304950e-04 -3.430532e-04
## ASV0250      3.299271e-04  3.474204e-04  3.659011e-04  3.854287e-04
## ASV0338      3.199225e-04  3.358315e-04  3.525528e-04  3.701290e-04
## ASV0450     -2.642927e-05 -2.793312e-05 -2.953128e-05 -3.123025e-05
## ASV0377      7.152733e-04  7.482391e-04  7.826723e-04  8.186335e-04
## ASV1022      9.227361e-05  9.658593e-05  1.010961e-04  1.058129e-04
## ASV6174     -8.294352e-05 -8.703113e-05 -9.132523e-05 -9.583664e-05
## ASV0786      6.794492e-05  7.049849e-05  7.311052e-05  7.577817e-05
## ASV0053     -6.588920e-04 -6.895654e-04 -7.216332e-04 -7.551556e-04
## ASV0697     -5.309726e-04 -5.549789e-04 -5.800139e-04 -6.061168e-04
## ASV0785      9.844302e-04  1.029384e-03  1.076308e-03  1.125279e-03
## ASV1967     -9.048045e-04 -9.459368e-04 -9.888480e-04 -1.033607e-03
## ASV0385      1.202424e-04  1.266140e-04  1.333404e-04  1.404420e-04
## ASV0295      3.343363e-05  3.555284e-05  3.782087e-05  4.024899e-05
## ASV0072     -6.389056e-04 -6.676540e-04 -6.976200e-04 -7.288483e-04
## ASV0157     -2.372819e-04 -2.474498e-04 -2.579973e-04 -2.689330e-04
## ASV0501      1.617369e-03  1.694210e-03  1.774664e-03  1.858898e-03
## ASV10729    -1.916559e-03 -2.006282e-03 -2.100130e-03 -2.198285e-03
## ASV1470      1.146794e-03  1.195409e-03  1.245816e-03  1.298060e-03
## ASV0050     -1.491783e-03 -1.560081e-03 -1.631381e-03 -1.705806e-03
## ASV0411     -2.704887e-04 -2.829067e-04 -2.958771e-04 -3.094231e-04
## ASV0549      4.748367e-04  4.971324e-04  5.204622e-04  5.448731e-04
## ASV0184      1.483383e-04  1.551454e-04  1.622530e-04  1.696732e-04
## ASV0705      3.835352e-04  4.013906e-04  4.200565e-04  4.395674e-04
## ASV1715      8.671903e-04  9.073450e-04  9.493060e-04  9.931499e-04
## ASV0603      1.361228e-04  1.425939e-04  1.493723e-04  1.564727e-04
## ASV0826      1.182343e-03  1.236195e-03  1.292387e-03  1.351011e-03
## ASV0034     -4.773255e-04 -4.989760e-04 -5.215580e-04 -5.451069e-04
## ASV0838      6.618099e-04  6.915464e-04  7.225300e-04  7.548041e-04
## ASV0614     -5.442771e-04 -5.693775e-04 -5.955972e-04 -6.229825e-04
## ASV0014     -8.539290e-04 -8.931992e-04 -9.342122e-04 -9.770396e-04
## ASV0585     -7.200107e-05 -7.547330e-05 -7.911823e-05 -8.294514e-05
## ASV0016     -8.956517e-04 -9.368514e-04 -9.798803e-04 -1.024814e-03
## ASV5394     -8.692011e-04 -9.096150e-04 -9.518607e-04 -9.960170e-04
## ASV0666      1.636540e-03  1.710599e-03  1.787828e-03  1.868347e-03
## ASV2085      3.805412e-04  3.954296e-04  4.107354e-04  4.264532e-04
## ASV0003     -6.216689e-04 -6.502348e-04 -6.800664e-04 -7.112157e-04
## ASV0346      1.505465e-04  1.583031e-04  1.664799e-04  1.751011e-04
## ASV0267     -8.459469e-05 -8.786460e-05 -9.121810e-05 -9.465244e-05
## ASV0353      4.995674e-04  5.238555e-04  5.493378e-04  5.760736e-04
## ASV2419      1.702506e-03  1.780139e-03  1.861153e-03  1.945681e-03
## ASV0447      7.039454e-04  7.373365e-04  7.723018e-04  8.089142e-04
## ASV0654      1.162160e-03  1.216053e-03  1.272376e-03  1.331234e-03
## ASV0151      9.382948e-05  9.870496e-05  1.038497e-04  1.092797e-04
## ASV0065     -4.739973e-04 -4.954159e-04 -5.177502e-04 -5.410348e-04
## ASV0527      1.257466e-03  1.315417e-03  1.375948e-03  1.439169e-03
## ASV4055     -2.884467e-04 -3.024727e-04 -3.171931e-04 -3.326433e-04
## ASV0166     -6.482150e-04 -6.764211e-04 -7.057365e-04 -7.361947e-04
## ASV0417     -4.825310e-04 -5.040896e-04 -5.265447e-04 -5.499273e-04
## ASV0078     -3.433558e-04 -3.586614e-04 -3.746017e-04 -3.911989e-04
## ASV0322     -4.150293e-04 -4.322385e-04 -4.500480e-04 -4.684690e-04
## ASV0156     -7.920154e-04 -8.278520e-04 -8.652307e-04 -9.042113e-04
## ASV0648     -2.411696e-03 -2.524690e-03 -2.642888e-03 -2.766523e-03
## ASV0407     -6.885651e-05 -7.223352e-05 -7.577750e-05 -7.949659e-05
## ASV2030     -3.269558e-04 -3.418581e-04 -3.574117e-04 -3.736427e-04
## ASV0300      2.037255e-04  2.137082e-04  2.241884e-04  2.351910e-04
## ASV1150     -1.928829e-05 -2.002265e-05 -2.077511e-05 -2.154507e-05
## ASV0958      6.067412e-04  6.356814e-04  6.660027e-04  6.977709e-04
## ASV0216     -7.008886e-04 -7.327787e-04 -7.660528e-04 -8.007651e-04
## ASV0446      1.032711e-03  1.081534e-03  1.132644e-03  1.186144e-03
## ASV0367     -7.776123e-04 -8.138438e-04 -8.517266e-04 -8.913327e-04
## ASV0200     -4.372141e-04 -4.572813e-04 -4.782364e-04 -5.001158e-04
## ASV0334     -2.716898e-04 -2.831723e-04 -2.950704e-04 -3.073926e-04
## ASV1311      2.907182e-04  3.037858e-04  3.174043e-04  3.315936e-04
## ASV0458      6.278205e-04  6.558093e-04  6.849547e-04  7.152963e-04
## ASV1371      6.547393e-05  6.861134e-05  7.189923e-05  7.534472e-05
## ASV0418      1.525350e-03  1.592903e-03  1.663218e-03  1.736389e-03
## ASV0004      1.476197e-04  1.542597e-04  1.611802e-04  1.683917e-04
## ASV1943      5.221417e-03  5.454604e-03  5.697510e-03  5.950478e-03
## ASV1495     -2.197440e-04 -2.315241e-04 -2.439829e-04 -2.571628e-04
## ASV0901     -9.637787e-04 -1.009017e-03 -1.056348e-03 -1.105867e-03
## ASV0628      4.514845e-04  4.716603e-04  4.926741e-04  5.145551e-04
## ASV0400      2.352229e-04  2.460603e-04  2.573783e-04  2.691964e-04
## ASV0116     -2.714220e-04 -2.840846e-04 -2.973262e-04 -3.111724e-04
## ASV0788      1.926703e-03  2.016670e-03  2.110754e-03  2.209133e-03
## ASV0117      1.681253e-04  1.762023e-04  1.846700e-04  1.935476e-04
## ASV3137     -6.012751e-06 -6.218207e-06 -6.425414e-06 -6.633665e-06
## ASV0001      1.782037e-04  1.861523e-04  1.944314e-04  2.030525e-04
## ASV1651      4.586130e-04  4.789417e-04  5.001027e-04  5.221240e-04
## ASV1692      1.606874e-03  1.682232e-03  1.761067e-03  1.843535e-03
## ASV0660      5.384493e-04  5.620539e-04  5.865923e-04  6.120916e-04
## ASV0508     -8.710736e-06 -9.345497e-06 -1.002975e-05 -1.076745e-05
## ASV1660     -4.621507e-04 -4.843810e-04 -5.076872e-04 -5.321215e-04
## ASV0233      3.432494e-04  3.590768e-04  3.756107e-04  3.928807e-04
## ASV1343     -1.084484e-03 -1.135312e-03 -1.188484e-03 -1.244105e-03
## ASV0209      5.023131e-04  5.249011e-04  5.484428e-04  5.729729e-04
## ASV0193     -6.825313e-04 -7.119036e-04 -7.424018e-04 -7.740572e-04
## ASV0357      1.243603e-04  1.305287e-04  1.370131e-04  1.438304e-04
## ASV0198      4.002369e-04  4.189384e-04  4.384943e-04  4.589416e-04
## ASV0007      1.867036e-04  1.949949e-04  2.036275e-04  2.126133e-04
## ASV1772     -2.717252e-04 -2.839078e-04 -2.965989e-04 -3.098162e-04
## ASV0009      1.746374e-04  1.823620e-04  1.904019e-04  1.987674e-04
## ASV0006     -2.016113e-05 -2.131461e-05 -2.253939e-05 -2.384013e-05
## ASV0011     -3.417590e-04 -3.577319e-04 -3.744366e-04 -3.919052e-04
## ASV0015      1.136696e-04  1.187174e-04  1.239722e-04  1.294409e-04
## ASV0017      1.234775e-04  1.289586e-04  1.346645e-04  1.406026e-04
## ASV0235     -4.237727e-04 -4.439440e-04 -4.650708e-04 -4.871977e-04
## ASV0382      1.747315e-04  1.834097e-04  1.925289e-04  2.021115e-04
## ASV2357      1.371108e-03  1.435125e-03  1.502073e-03  1.572079e-03
## ASV0567     -3.642738e-04 -3.809941e-04 -3.984551e-04 -4.166875e-04
## ASV0165      2.399475e-04  2.512369e-04  2.630502e-04  2.754110e-04
## ASV0005      2.933754e-04  3.067485e-04  3.207042e-04  3.352654e-04
## ASV0384     -1.971222e-05 -2.014385e-05 -2.054924e-05 -2.092296e-05
## ASV0002      5.020484e-05  5.250910e-05  5.491509e-05  5.742696e-05
## ASV3017      1.890989e-03  1.976670e-03  2.066035e-03  2.159224e-03
## ASV0091     -6.983997e-07 -6.974338e-07 -6.936239e-07 -6.866364e-07
## ASV0186     -7.653420e-04 -8.008051e-04 -8.378647e-04 -8.765880e-04
## ASV0370      2.245204e-04  2.351225e-04  2.462211e-04  2.578391e-04
## ASV0018      4.002376e-04  4.185160e-04  4.375940e-04  4.575033e-04
## ASV1377      6.074806e-03  6.351490e-03  6.640188e-03  6.941368e-03
## ASV0019      4.191554e-04  4.383084e-04  4.583001e-04  4.791641e-04
## ASV0023     -1.232265e-04 -1.291846e-04 -1.354330e-04 -1.419856e-04
## ASV2194      4.709575e-04  4.924964e-04  5.149853e-04  5.384637e-04
## ASV1155      9.030860e-04  9.450757e-04  9.889666e-04  1.034840e-03
## ASV0510     -6.990027e-04 -7.283598e-04 -7.587770e-04 -7.902778e-04
## ASV2371     -1.023929e-03 -1.069720e-03 -1.117420e-03 -1.167096e-03
## ASV0024     -1.668856e-04 -1.748735e-04 -1.832436e-04 -1.920140e-04
## ASV2452      1.182117e-03  1.234847e-03  1.289767e-03  1.346953e-03
## ASV2332     -1.358340e-03 -1.420771e-03 -1.485934e-03 -1.553934e-03
## ASV2591      9.012090e-04  9.457904e-04  9.926385e-04  1.041873e-03
## ASV0521      6.402337e-04  6.703224e-04  7.018041e-04  7.347412e-04
## ASV5542      5.595041e-04  5.858285e-04  6.133730e-04  6.421921e-04
## ASV0336     -2.089300e-04 -2.179099e-04 -2.272378e-04 -2.369245e-04
## ASV10102     1.175072e-03  1.230409e-03  1.288322e-03  1.348927e-03
## ASV16823    -1.709150e-03 -1.785408e-03 -1.864830e-03 -1.947526e-03
## ASV3104      9.431270e-03  9.852025e-03  1.029024e-02  1.074651e-02
## ASV0781      1.077348e-03  1.127493e-03  1.179918e-03  1.234721e-03
## ASV10899     6.666009e-04  6.996091e-04  7.342999e-04  7.707622e-04
## ASV11222    -2.984959e-03 -3.118120e-03 -3.256805e-03 -3.401206e-03
## ASV11327    -2.684560e-03 -2.804308e-03 -2.929022e-03 -3.058876e-03
## ASV12458    -2.984404e-03 -3.117514e-03 -3.256144e-03 -3.400485e-03
## ASV1636      2.359255e-04  2.472466e-04  2.591129e-04  2.715505e-04
## ASV1890     -1.935547e-03 -2.021258e-03 -2.110463e-03 -2.203280e-03
## ASV2898      2.277598e-03  2.381456e-03  2.489835e-03  2.602913e-03
## ASV8328      7.163703e-05  7.868076e-05  8.638658e-05  9.481400e-05
## ASV0709     -2.524956e-03 -2.640693e-03 -2.761524e-03 -2.887656e-03
## ASV0856      1.749131e-03  1.832061e-03  1.918901e-03  2.009832e-03
## ASV0909     -1.514741e-04 -1.549247e-04 -1.582038e-04 -1.612747e-04
## ASV0937     -1.464867e-03 -1.532908e-03 -1.604032e-03 -1.678372e-03
## ASV11390    -4.227014e-03 -4.415524e-03 -4.611849e-03 -4.816260e-03
## ASV11966     9.927554e-04  1.040565e-03  1.090695e-03  1.143259e-03
## ASV12990     6.690244e-04  7.000883e-04  7.325560e-04  7.664870e-04
## ASV14797     1.143791e-03  1.195691e-03  1.249826e-03  1.306282e-03
## ASV14904    -6.000250e-03 -6.267834e-03 -6.546511e-03 -6.836666e-03
## ASV15304     5.226636e-04  5.487936e-04  5.762764e-04  6.051852e-04
## ASV16696    -2.122363e-03 -2.217004e-03 -2.315568e-03 -2.418191e-03
## ASV1690      3.550923e-03  3.719120e-03  3.895218e-03  4.079580e-03
## ASV2029      2.572090e-03  2.689660e-03  2.812374e-03  2.940438e-03
## ASV2834      4.128989e-03  4.320784e-03  4.521257e-03  4.730781e-03
## ASV4003      2.462755e-03  2.581226e-03  2.705442e-03  2.835683e-03
## ASV4064      1.554871e-03  1.626587e-03  1.701502e-03  1.779749e-03
## ASV4294      8.635866e-04  9.064412e-04  9.514922e-04  9.988575e-04
## ASV4609      4.808957e-04  5.023660e-04  5.247350e-04  5.480356e-04
## ASV6283     -1.985660e-03 -2.074210e-03 -2.166431e-03 -2.262450e-03
## ASV6491     -2.831388e-03 -2.957641e-03 -3.089127e-03 -3.226028e-03
## ASV7453      1.257762e-03  1.318546e-03  1.382294e-03  1.449153e-03
## ASV7959      3.187091e-04  3.357527e-04  3.537733e-04  3.728312e-04
## ASV8219      2.918251e-02  3.048370e-02  3.183883e-02  3.324975e-02
## ASV8547     -2.539038e-03 -2.652239e-03 -2.770129e-03 -2.892873e-03
## ASV9319      1.086770e-03  1.138065e-03  1.191759e-03  1.247959e-03
## ASV9382     -4.897302e-03 -5.115631e-03 -5.343006e-03 -5.579739e-03
## ASV11516    -3.302490e-03 -3.449705e-03 -3.603019e-03 -3.762642e-03
## ASV14377    -2.397380e-03 -2.504239e-03 -2.615522e-03 -2.731384e-03
## ASV1867      1.999466e-03  2.092951e-03  2.190725e-03  2.292979e-03
## ASV1895      3.423449e-04  3.580953e-04  3.745368e-04  3.916961e-04
## ASV3168      1.105872e-03  1.155950e-03  1.208174e-03  1.262623e-03
## ASV4449      7.079012e-03  7.404333e-03  7.744064e-03  8.098796e-03
## ASV6596      1.334699e-03  1.399564e-03  1.467635e-03  1.539075e-03
## ASV7492     -3.319698e-04 -3.446462e-04 -3.576458e-04 -3.709602e-04
## ASV9854     -6.260990e-04 -6.535500e-04 -6.820951e-04 -7.117680e-04
## ASV6296      5.380073e-02  5.619846e-02  5.869547e-02  6.129519e-02
## ASV4201      5.636201e-04  5.930049e-04  6.240160e-04  6.567499e-04
## ASV0552      1.299483e-03  1.360329e-03  1.423973e-03  1.490537e-03
## ASV3671     -6.722876e-04 -7.022394e-04 -7.334345e-04 -7.659167e-04
## ASV3529     -3.429963e-04 -3.566597e-04 -3.707364e-04 -3.852261e-04
## ASV1060      5.005357e-04  5.240138e-04  5.485763e-04  5.742720e-04
## ASV0239     -5.334610e-04 -5.569262e-04 -5.813298e-04 -6.067007e-04
## ASV5711     -2.076942e-03 -2.171298e-03 -2.269733e-03 -2.372405e-03
## ASV4152     -3.373225e-03 -3.527972e-03 -3.689544e-03 -3.858217e-03
## ASV1461      1.562531e-03  1.632483e-03  1.705358e-03  1.781259e-03
## ASV2877      8.084053e-04  8.445484e-04  8.821966e-04  9.214023e-04
## ASV0012      1.108562e-04  1.160012e-04  1.213786e-04  1.269983e-04
## ASV9823      2.644545e-04  2.743316e-04  2.844542e-04  2.948172e-04
## ASV0008      1.186589e-04  1.241372e-04  1.298604e-04  1.358386e-04
## ASV7832     -2.107181e-03 -2.204490e-03 -2.306153e-03 -2.412352e-03
## ASV1915     -4.790466e-05 -4.941853e-05 -5.093823e-05 -5.245878e-05
## ASV0055      1.356544e-05  1.384991e-05  1.411447e-05  1.435517e-05
## ASV0032      2.244720e-04  2.346298e-04  2.452229e-04  2.562678e-04
## ASV2977     -2.952261e-03 -3.086858e-03 -3.227310e-03 -3.373847e-03
## ASV0466      2.211325e-03  2.309535e-03  2.411774e-03  2.518178e-03
## ASV3866      1.495418e-03  1.565353e-03  1.638499e-03  1.714995e-03
## ASV0040      3.968618e-04  4.153113e-04  4.345971e-04  4.547551e-04
## ASV0496     -1.390236e-04 -1.469233e-04 -1.553142e-04 -1.642298e-04
## ASV0052      5.072614e-04  5.306451e-04  5.550709e-04  5.805818e-04
## ASV3828     -3.124636e-03 -3.267920e-03 -3.417527e-03 -3.573712e-03
## ASV1930      9.811852e-04  1.026471e-03  1.073777e-03  1.123187e-03
## ASV2126      1.211410e-03  1.266858e-03  1.324740e-03  1.385154e-03
## ASV0793      1.372532e-03  1.436525e-03  1.503435e-03  1.573388e-03
## ASV0299     -1.097839e-04 -1.148426e-04 -1.201270e-04 -1.256465e-04
## ASV0208      9.804511e-04  1.026568e-03  1.074823e-03  1.125313e-03
## ASV0511     -5.672391e-04 -5.925395e-04 -6.188899e-04 -6.463271e-04
## ASV1123     -1.804974e-03 -1.884829e-03 -1.967935e-03 -2.054398e-03
## ASV0099     -5.712482e-05 -5.935750e-05 -6.165306e-05 -6.401083e-05
## ASV0752     -5.457514e-04 -5.720921e-04 -5.997178e-04 -6.286924e-04
## ASV0883      6.948929e-04  7.276673e-04  7.619699e-04  7.978702e-04
## ASV0683      1.449395e-03  1.517807e-03  1.589416e-03  1.664368e-03
## ASV4117     -3.578086e-03 -3.741983e-03 -3.913089e-03 -4.091694e-03
## ASV2172      2.902924e-04  3.032701e-04  3.167897e-04  3.308702e-04
## ASV0330     -4.150092e-04 -4.341357e-04 -4.541165e-04 -4.749875e-04
## ASV0728      2.186674e-03  2.287776e-03  2.393411e-03  2.503767e-03
## ASV0499      5.288486e-04  5.538138e-04  5.799469e-04  6.073014e-04
## ASV0120     -9.112331e-04 -9.532522e-04 -9.971437e-04 -1.042985e-03
## ASV1446      9.024236e-04  9.414718e-04  9.820198e-04  1.024107e-03
## ASV17171    -1.626279e-03 -1.701281e-03 -1.779631e-03 -1.861469e-03
## ASV0533      1.498115e-04  1.570376e-04  1.646156e-04  1.725630e-04
## ASV2495     -5.821305e-04 -6.104314e-04 -6.401337e-04 -6.713090e-04
## ASV5582      7.309498e-04  7.619286e-04  7.940382e-04  8.273031e-04
## ASV1488      6.114142e-04  6.420447e-04  6.742430e-04  7.080894e-04
## ASV0682      3.937470e-04  4.125193e-04  4.321867e-04  4.527919e-04
## ASV0068     -4.302968e-04 -4.503006e-04 -4.712100e-04 -4.930636e-04
## ASV1987     -1.601030e-03 -1.677355e-03 -1.757317e-03 -1.841090e-03
## ASV0035     -6.188724e-05 -6.547520e-05 -6.929294e-05 -7.335663e-05
## ASV7192     -1.219316e-03 -1.274320e-03 -1.331662e-03 -1.391429e-03
## ASV0873      5.359263e-04  5.497158e-04  5.631239e-04  5.760460e-04
## ASV4749      9.560970e-06  7.516994e-06  5.148553e-06  2.420378e-06
## ASV2174      1.174616e-03  1.225005e-03  1.277319e-03  1.331613e-03
## ASV1476     -7.488994e-04 -7.838414e-04 -8.203820e-04 -8.585917e-04
## ASV0740     -2.581326e-03 -2.702473e-03 -2.829219e-03 -2.961814e-03
## ASV0170     -3.339554e-04 -3.494603e-04 -3.656662e-04 -3.826028e-04
## ASV2466     -2.504835e-03 -2.620658e-03 -2.741680e-03 -2.868120e-03
## ASV1709      1.049741e-03  1.096920e-03  1.146091e-03  1.197328e-03
## ASV6170     -5.918095e-03 -6.185723e-03 -6.464891e-03 -6.756055e-03
## ASV3673      1.774010e-03  1.853306e-03  1.935942e-03  2.022046e-03
## ASV1745      2.860677e-04  2.962758e-04  3.066949e-04  3.173154e-04
## ASV0380     -1.447593e-03 -1.504983e-03 -1.564144e-03 -1.625088e-03
## ASV0426      7.459865e-05  7.980886e-05  8.540406e-05  9.141281e-05
## ASV0202      5.478387e-06  6.831661e-06  8.346964e-06  1.004028e-05
## ASV6350     -1.960609e-03 -2.046201e-03 -2.135229e-03 -2.227810e-03
## ASV0713     -8.175259e-04 -8.556194e-04 -8.954499e-04 -9.370932e-04
## ASV1822      6.361785e-05  6.756230e-05  7.176592e-05  7.624579e-05
## ASV4569      2.502703e-03  2.614922e-03  2.731889e-03  2.853783e-03
## ASV0030     -2.221063e-04 -2.325855e-04 -2.435517e-04 -2.550266e-04
## ASV0331      8.803717e-04  9.221390e-04  9.658763e-04  1.011675e-03
## ASV2981      2.519796e-03  2.638060e-03  2.761774e-03  2.891178e-03
## ASV0828     -3.689379e-04 -3.947030e-04 -4.223879e-04 -4.521381e-04
## ASV2440      2.198033e-03  2.300953e-03  2.408603e-03  2.521191e-03
## ASV3006     -1.199190e-02 -1.248427e-02 -1.299367e-02 -1.352044e-02
## ASV3875      1.114931e-01  1.160705e-01  1.208061e-01  1.257032e-01
## ASV4511      1.237052e-03  1.295357e-03  1.356382e-03  1.420250e-03
## ASV4700     -4.409270e-03 -4.590277e-03 -4.777542e-03 -4.971191e-03
## ASV5804     -1.035424e-01 -1.077926e-01 -1.121898e-01 -1.167368e-01
## ASV6826      1.776635e-03  1.861000e-03  1.949356e-03  2.041889e-03
## ASV7280      1.650478e-03  1.730119e-03  1.813609e-03  1.901132e-03
## ASV7535     -4.408687e-03 -4.589648e-03 -4.776864e-03 -4.970461e-03
## ASV0651     -8.908741e-04 -9.307847e-04 -9.723610e-04 -1.015661e-03
## ASV0913      2.017800e-03  2.112853e-03  2.212336e-03  2.316453e-03
## ASV10832    -4.704131e-03 -4.897202e-03 -5.096947e-03 -5.303497e-03
## ASV1117     -4.618002e-03 -4.825045e-03 -5.040837e-03 -5.265705e-03
## ASV11329     6.976420e-04  7.338301e-04  7.719855e-04  8.122199e-04
## ASV13209     1.014705e-04  1.113225e-04  1.220323e-04  1.336661e-04
## ASV1345      1.075583e-03  1.127598e-03  1.182111e-03  1.239237e-03
## ASV1719     -6.624215e-03 -6.896068e-03 -7.177314e-03 -7.468142e-03
## ASV1886      1.234943e-03  1.290848e-03  1.349172e-03  1.410012e-03
## ASV2158     -7.721157e-05 -7.504467e-05 -7.232689e-05 -6.900365e-05
## ASV2189      2.076705e-03  2.172227e-03  2.271997e-03  2.376192e-03
## ASV2257      2.155571e-03  2.253733e-03  2.356200e-03  2.463150e-03
## ASV2283      5.131272e-03  5.341813e-03  5.559625e-03  5.784855e-03
## ASV2328      3.161151e-03  3.290845e-03  3.425017e-03  3.563757e-03
## ASV2434     -2.987580e-03 -3.119336e-03 -3.256502e-03 -3.399272e-03
## ASV2648      5.769929e-03  6.006605e-03  6.251449e-03  6.504625e-03
## ASV2698      5.657774e-03  5.921150e-03  6.196540e-03  6.484475e-03
## ASV2775      1.770982e-03  1.848991e-03  1.930164e-03  2.014609e-03
## ASV3171      2.781223e-03  2.895283e-03  3.013277e-03  3.135284e-03
## ASV3227      2.730832e-03  2.850308e-03  2.974553e-03  3.103721e-03
## ASV3397      1.285534e-03  1.347181e-03  1.411746e-03  1.479358e-03
## ASV3444      3.915444e-03  4.086617e-03  4.264689e-03  4.449894e-03
## ASV3556      1.156755e-02  1.204184e-02  1.253247e-02  1.303979e-02
## ASV3606     -2.718812e-02 -2.830277e-02 -2.945585e-02 -3.064810e-02
## ASV4190      3.633569e-03  3.801405e-03  3.976779e-03  4.160014e-03
## ASV4197      2.314555e-03  2.415647e-03  2.520776e-03  2.630073e-03
## ASV4722      3.489294e-03  3.647716e-03  3.813004e-03  3.985428e-03
## ASV4765      1.832252e-03  1.918912e-03  2.009565e-03  2.104383e-03
## ASV4809      6.834723e-03  7.114872e-03  7.404671e-03  7.704313e-03
## ASV4846      3.143917e-03  3.290136e-03  3.442972e-03  3.602706e-03
## ASV4903     -1.672373e-04 -1.689308e-04 -1.702147e-04 -1.710369e-04
## ASV4944     -2.799210e-03 -2.913940e-03 -3.032622e-03 -3.155334e-03
## ASV5151      4.594312e-04  4.512638e-04  4.402749e-04  4.261556e-04
## ASV5413     -6.157622e-03 -6.409985e-03 -6.671039e-03 -6.940957e-03
## ASV5537     -6.615115e-03 -6.886204e-03 -7.166627e-03 -7.456570e-03
## ASV5688      5.560087e-03  5.787921e-03  6.023598e-03  6.267275e-03
## ASV5752      1.607860e-03  1.685095e-03  1.766001e-03  1.850745e-03
## ASV6122     -7.122334e-03 -7.414168e-03 -7.716047e-03 -8.028172e-03
## ASV6135      3.738996e-03  3.892186e-03  4.050648e-03  4.214487e-03
## ASV6188     -2.270135e-02 -2.363137e-02 -2.459339e-02 -2.558804e-02
## ASV6216      5.093785e-03  5.319015e-03  5.553498e-03  5.797560e-03
## ASV6242      3.738082e-03  3.891195e-03  4.049574e-03  4.213323e-03
## ASV6383      2.337241e-02  2.432966e-02  2.531984e-02  2.634358e-02
## ASV6781      5.201463e-03  5.414480e-03  5.634820e-03  5.862629e-03
## ASV6799     -9.877422e-03 -1.028190e-02 -1.070028e-02 -1.113284e-02
## ASV7374     -2.095925e-03 -2.181745e-03 -2.270514e-03 -2.362291e-03
## ASV7539     -2.796224e-03 -2.910708e-03 -3.029127e-03 -3.151557e-03
## ASV8591     -7.116367e-03 -7.407705e-03 -7.709051e-03 -8.020603e-03
## ASV8637      3.124055e-02  3.251940e-02  3.384217e-02  3.520974e-02
## ASV12796    -4.122641e-03 -4.291389e-03 -4.465933e-03 -4.646384e-03
## ASV1934      2.101694e-03  2.199303e-03  2.301336e-03  2.407983e-03
## ASV22549     1.845776e-04  1.971184e-04  2.105472e-04  2.249254e-04
## ASV29857    -1.599080e-03 -1.664529e-03 -1.732226e-03 -1.802214e-03
## ASV3215      2.228344e-03  2.333570e-03  2.443728e-03  2.559048e-03
## ASV3236     -4.121938e-03 -4.290630e-03 -4.465113e-03 -4.645500e-03
## ASV3954     -4.121589e-03 -4.290252e-03 -4.464704e-03 -4.645058e-03
## ASV4850      2.762848e-03  2.875899e-03  2.992830e-03  3.113716e-03
## ASV5225      2.667900e-02  2.777057e-02  2.889958e-02  3.006678e-02
## ASV5532     -1.424971e-03 -1.483269e-03 -1.543566e-03 -1.605902e-03
## ASV7258      1.100440e-03  1.159027e-03  1.220910e-03  1.286284e-03
## ASV9474     -4.432889e-04 -4.567769e-04 -4.702968e-04 -4.838075e-04
## ASV11857    -5.354034e-03 -5.573065e-03 -5.799608e-03 -6.033811e-03
## ASV1202     -3.399986e-03 -3.539065e-03 -3.682914e-03 -3.831626e-03
## ASV14742     9.166481e-04  9.629751e-04  1.011725e-03  1.063028e-03
## ASV16652     7.093106e-04  7.439219e-04  7.802130e-04  8.182607e-04
## ASV2019      2.499465e-03  2.610399e-03  2.725926e-03  2.846210e-03
## ASV2410     -5.523239e-03 -5.777303e-03 -6.042716e-03 -6.319960e-03
## ASV2718      1.362234e-03  1.426981e-03  1.494782e-03  1.565775e-03
## ASV2738      4.102635e-03  4.284052e-03  4.472894e-03  4.669414e-03
## ASV2876      2.472060e-03  2.573164e-03  2.677733e-03  2.785835e-03
## ASV3177      3.312517e-03  3.447982e-03  3.588090e-03  3.732931e-03
## ASV4367      4.093120e-03  4.260493e-03  4.433602e-03  4.612557e-03
## ASV4635      1.250764e-03  1.314358e-03  1.381269e-03  1.451669e-03
## ASV4896      9.068501e-04  9.570218e-04  1.010155e-03  1.066432e-03
## ASV4907      1.061692e-03  1.114683e-03  1.170386e-03  1.228941e-03
## ASV5230     -3.186386e-03 -3.316693e-03 -3.451466e-03 -3.590794e-03
## ASV6509     -3.398618e-03 -3.537592e-03 -3.681329e-03 -3.829922e-03
## ASV7376     -2.431470e-03 -2.530888e-03 -2.633712e-03 -2.740009e-03
## ASV8163     -3.623005e-03 -3.771129e-03 -3.924328e-03 -4.082699e-03
## ASV8195     -3.185307e-03 -3.315525e-03 -3.450203e-03 -3.589428e-03
## ASV8923      9.761298e-04  1.024457e-03  1.075215e-03  1.128524e-03
## ASV9666     -1.713516e-03 -1.776033e-03 -1.839983e-03 -1.905324e-03
## ASV1482      1.658516e-03  1.737139e-03  1.819454e-03  1.905630e-03
## ASV2726      1.524206e-03  1.596721e-03  1.672659e-03  1.752176e-03
## ASV3281     -1.327168e-02 -1.381422e-02 -1.437534e-02 -1.495541e-02
## ASV4235     -1.327055e-02 -1.381300e-02 -1.437403e-02 -1.495399e-02
## ASV4808      2.701281e-03  2.820899e-03  2.945463e-03  3.075151e-03
## ASV4861     -6.619130e-03 -6.910179e-03 -7.213113e-03 -7.528352e-03
## ASV5276      3.854915e-03  4.025439e-03  4.202980e-03  4.387787e-03
## ASV5837      1.238202e-03  1.296226e-03  1.356935e-03  1.420452e-03
## ASV7098      1.782180e-03  1.865163e-03  1.951938e-03  2.042672e-03
## ASV8451     -2.258463e-03 -2.350739e-03 -2.446170e-03 -2.544819e-03
## ASV8694     -1.326428e-02 -1.380618e-02 -1.436661e-02 -1.494593e-02
## ASV0905     -5.704188e-04 -5.979063e-04 -6.266919e-04 -6.568312e-04
## ASV2900      3.055073e-03  3.185694e-03  3.321314e-03  3.462084e-03
## ASV3963     -3.111874e-03 -3.242922e-03 -3.378818e-03 -3.519692e-03
## ASV0041     -5.351441e-04 -5.604522e-04 -5.869434e-04 -6.146713e-04
## ASV1865      1.572966e-03  1.649120e-03  1.728980e-03  1.812723e-03
## ASV1140      8.866694e-04  9.290328e-04  9.733969e-04  1.019852e-03
## ASV1179      9.234815e-04  9.663638e-04  1.011183e-03  1.058020e-03
## ASV0279      1.412061e-03  1.476357e-03  1.543458e-03  1.613478e-03
## ASV0043     -2.423603e-04 -2.544680e-04 -2.672039e-04 -2.806025e-04
## ASV2097     -8.501721e-04 -8.874484e-04 -9.262412e-04 -9.666044e-04
## ASV0309     -1.674300e-04 -1.749248e-04 -1.827351e-04 -1.908725e-04
## ASV0607      2.195910e-03  2.298365e-03  2.405500e-03  2.517518e-03
## ASV0025     -6.098283e-04 -6.384558e-04 -6.684037e-04 -6.997304e-04
## ASV2284     -2.427630e-03 -2.532289e-03 -2.641019e-03 -2.753945e-03
## ASV0556      6.131028e-04  6.430140e-04  6.744017e-04  7.073391e-04
## ASV5040     -2.010490e-03 -2.136200e-03 -2.270284e-03 -2.413308e-03
## ASV2924     -7.815952e-03 -8.146628e-03 -8.489638e-03 -8.845319e-03
## ASV1331      1.952256e-03  2.042290e-03  2.136347e-03  2.234598e-03
## ASV0506     -8.679709e-04 -9.047504e-04 -9.428863e-04 -9.824113e-04
## ASV1514      2.956993e-03  3.093513e-03  3.236129e-03  3.385096e-03
## ASV2144      2.822442e-03  2.952397e-03  3.088140e-03  3.229913e-03
## ASV2265      1.854912e-03  1.940654e-03  2.030241e-03  2.123833e-03
## ASV5156      1.467480e-03  1.526958e-03  1.588398e-03  1.651826e-03
## ASV5534      4.520044e-04  4.691905e-04  4.868301e-04  5.049168e-04
## ASV5747     -3.999617e-04 -4.359745e-04 -4.750902e-04 -5.175573e-04
## ASV6657      1.456660e-03  1.521189e-03  1.588370e-03  1.658294e-03
## ASV0658     -1.091857e-03 -1.138745e-03 -1.187424e-03 -1.237945e-03
## ASV0716      1.941436e-03  2.028414e-03  2.119037e-03  2.213435e-03
## ASV1657      3.782226e-03  3.946111e-03  4.116392e-03  4.293259e-03
## ASV1885      3.230440e-03  3.363620e-03  3.501386e-03  3.643817e-03
## ASV2333      1.678615e-03  1.754998e-03  1.834699e-03  1.917847e-03
## ASV3375      1.319574e-03  1.377240e-03  1.437212e-03  1.499565e-03
## ASV4317      1.162810e-03  1.216815e-03  1.273278e-03  1.332308e-03
## ASV9599     -1.679670e-04 -1.830891e-04 -1.995139e-04 -2.173458e-04
## ASV0175     -1.826442e-03 -1.908832e-03 -1.994725e-03 -2.084250e-03
## ASV1032      7.806835e-04  8.144083e-04  8.494420e-04  8.858229e-04
## ASV1235      1.423304e-03  1.481269e-03  1.541149e-03  1.602968e-03
## ASV1262      1.875277e-03  1.960809e-03  2.050072e-03  2.143213e-03
## ASV1320      1.073087e-03  1.125848e-03  1.181256e-03  1.239445e-03
## ASV13797     1.090098e-03  1.138975e-03  1.189918e-03  1.243005e-03
## ASV1491      1.557162e-03  1.634871e-03  1.716538e-03  1.802363e-03
## ASV15014    -1.306300e-04 -1.423881e-04 -1.551587e-04 -1.690229e-04
## ASV1510      2.152396e-03  2.255375e-03  2.363257e-03  2.476268e-03
## ASV1551      7.330321e-03  7.670227e-03  8.025466e-03  8.396689e-03
## ASV1919      7.800981e-04  8.285597e-04  8.802415e-04  9.353611e-04
## ASV2114      1.361824e-03  1.421638e-03  1.483879e-03  1.548630e-03
## ASV21486    -1.121892e-04 -1.222847e-04 -1.332492e-04 -1.451522e-04
## ASV2448      1.402252e-03  1.465063e-03  1.530516e-03  1.598708e-03
## ASV2589      2.659060e-03  2.774587e-03  2.894665e-03  3.019438e-03
## ASV2608      1.774034e-03  1.854148e-03  1.937695e-03  2.024805e-03
## ASV2786      3.546229e-03  3.709098e-03  3.879221e-03  4.056907e-03
## ASV2827      1.256978e-03  1.313386e-03  1.372172e-03  1.433423e-03
## ASV2872      5.469257e-03  5.710578e-03  5.961688e-03  6.222907e-03
## ASV3125      1.069168e-03  1.116100e-03  1.164922e-03  1.215696e-03
## ASV3247      2.342762e-03  2.446458e-03  2.554402e-03  2.666739e-03
## ASV3451     -3.476479e-04 -3.789306e-04 -4.129060e-04 -4.497894e-04
## ASV3465      6.025780e-05  5.844855e-05  5.616302e-05  5.334907e-05
## ASV3809      3.157824e-03  3.296686e-03  3.441158e-03  3.591423e-03
## ASV4006      1.537383e-03  1.605605e-03  1.676635e-03  1.750567e-03
## ASV4046      2.259478e-03  2.359581e-03  2.463799e-03  2.572275e-03
## ASV4938      1.777329e-04  1.779925e-04  1.775894e-04  1.764424e-04
## ASV5435     -5.899576e-04 -6.430315e-04 -7.006721e-04 -7.632445e-04
## ASV5605      1.302573e-03  1.355367e-03  1.409886e-03  1.466150e-03
## ASV5635     -1.967968e-04 -2.144987e-04 -2.337234e-04 -2.545927e-04
## ASV5743      1.075848e-03  1.124062e-03  1.174310e-03  1.226665e-03
## ASV6627     -2.042566e-04 -2.226281e-04 -2.425798e-04 -2.642381e-04
## ASV6785     -2.273798e-04 -2.478291e-04 -2.700371e-04 -2.941443e-04
## ASV7368      1.332613e-03  1.394200e-03  1.458555e-03  1.525797e-03
## ASV9118      4.815003e-04  5.010535e-04  5.212570e-04  5.421207e-04
## ASV9135      8.939070e-04  9.287912e-04  9.646902e-04  1.001603e-03
## ASV9435      1.081945e-03  1.127011e-03  1.173665e-03  1.221939e-03
## ASV9671     -2.916180e-04 -3.178402e-04 -3.463169e-04 -3.772282e-04
## ASV0387     -1.897580e-03 -1.980128e-03 -2.065924e-03 -2.155066e-03
## ASV0454     -3.046355e-03 -3.181047e-03 -3.321234e-03 -3.467102e-03
## ASV0751     -8.725602e-04 -9.092671e-04 -9.473051e-04 -9.867040e-04
## ASV1081      1.845208e-03  1.929925e-03  2.018375e-03  2.110708e-03
## ASV1332      3.283138e-03  3.431078e-03  3.585295e-03  3.746021e-03
## ASV2659      3.634629e-03  3.802344e-03  3.977522e-03  4.160466e-03
## ASV2979      1.617184e-03  1.688104e-03  1.761863e-03  1.838550e-03
## ASV4184      2.318111e-03  2.415019e-03  2.515381e-03  2.619268e-03
## ASV6198      7.448976e-04  7.774868e-04  8.113903e-04  8.466532e-04
## ASV7454      7.949319e-04  8.296512e-04  8.657471e-04  9.032623e-04
## ASV8198      6.794858e-04  7.052556e-04  7.316951e-04  7.587930e-04
## ASV0855      1.984869e-03  2.076112e-03  2.171401e-03  2.270902e-03
## ASV10092     9.062691e-04  9.460519e-04  9.874399e-04  1.030486e-03
## ASV1532      1.770209e-03  1.853759e-03  1.941214e-03  2.032753e-03
## ASV2553      3.163142e-03  3.308800e-03  3.460940e-03  3.619832e-03
## ASV2741      4.330130e-03  4.535365e-03  4.750236e-03  4.975184e-03
## ASV4095      2.588179e-03  2.714760e-03  2.847581e-03  2.986945e-03
## ASV5295      9.176296e-04  9.563778e-04  9.965445e-04  1.038163e-03
## ASV5787     -1.199397e-04 -1.307208e-04 -1.424284e-04 -1.551363e-04
## ASV9455      1.225581e-03  1.280140e-03  1.336972e-03  1.396158e-03
## ASV10879     1.119947e-03  1.170608e-03  1.223453e-03  1.278568e-03
## ASV3997      1.448875e-03  1.518718e-03  1.591924e-03  1.668651e-03
## ASV6760      4.151443e-04  4.281994e-04  4.413154e-04  4.544527e-04
## ASV6990      1.152763e-03  1.203148e-03  1.255549e-03  1.310032e-03
## ASV9560      7.349809e-04  7.659773e-04  7.981158e-04  8.314256e-04
## ASV0220     -1.729777e-04 -1.808614e-04 -1.890889e-04 -1.976740e-04
## ASV2518      7.208020e-04  7.540438e-04  7.887686e-04  8.250380e-04
## ASV3615      1.820015e-03  1.902437e-03  1.988406e-03  2.078060e-03
## ASV0075     -5.943896e-06 -6.349192e-06 -6.783128e-06 -7.247658e-06
## ASV8070      8.761507e-05  8.935405e-05  9.097369e-05  9.245314e-05
## ASV1658      7.236763e-04  7.554342e-04  7.884714e-04  8.228301e-04
## ASV0773      1.331948e-03  1.391232e-03  1.452976e-03  1.517267e-03
## ASV0799      1.499639e-04  1.559563e-04  1.621297e-04  1.684835e-04
## ASV1839     -9.206707e-04 -9.621623e-04 -1.005412e-03 -1.050483e-03
## ASV0265      1.073849e-03  1.124957e-03  1.178487e-03  1.234552e-03
## ASV3741      3.883898e-04  4.050758e-04  4.223903e-04  4.403483e-04
## ASV0847      1.476720e-03  1.544927e-03  1.616185e-03  1.690624e-03
## ASV1026      1.938714e-03  2.027074e-03  2.119276e-03  2.215472e-03
## ASV1222     -5.207621e-04 -5.411054e-04 -5.620478e-04 -5.835903e-04
## ASV0729     -3.119932e-05 -3.267210e-05 -3.421399e-05 -3.582820e-05
## ASV0143     -4.896017e-04 -5.112620e-04 -5.338090e-04 -5.572730e-04
## ASV1328      2.386134e-04  2.509579e-04  2.639745e-04  2.777016e-04
## ASV9078     -5.359822e-04 -5.651863e-04 -5.960809e-04 -6.287682e-04
## ASV0027     -5.749802e-04 -6.019219e-04 -6.301016e-04 -6.595734e-04
## ASV0546     -6.686782e-04 -6.978726e-04 -7.282318e-04 -7.597934e-04
## ASV1136      1.613412e-03  1.687359e-03  1.764571e-03  1.845183e-03
## ASV3081      8.470649e-04  8.861665e-04  9.270263e-04  9.697203e-04
## ASV0531      2.516932e-04  2.647790e-04  2.785789e-04  2.931337e-04
## ASV2525      1.261963e-03  1.318262e-03  1.376908e-03  1.437985e-03
## ASV1083     -2.533633e-04 -2.633894e-04 -2.737231e-04 -2.843663e-04
## ASV0424     -1.799530e-04 -1.883998e-04 -1.972363e-04 -2.064796e-04
## ASV0644      8.422765e-05  9.179800e-05  1.000188e-04  1.089420e-04
## ASV6007     -8.411299e-05 -9.169868e-05 -9.993990e-05 -1.088895e-04
## ASV0564      5.976237e-04  6.261218e-04  6.559707e-04  6.872328e-04
## ASV1938      1.879896e-03  1.959982e-03  2.043064e-03  2.129218e-03
## ASV6516     -2.931713e-03 -3.067616e-03 -3.209652e-03 -3.358083e-03
## ASV0503     -1.171293e-03 -1.221645e-03 -1.273923e-03 -1.328181e-03
## ASV6913     -5.846435e-03 -6.111344e-03 -6.387732e-03 -6.676058e-03
## ASV0164     -7.260890e-04 -7.600982e-04 -7.956735e-04 -8.328846e-04
## ASV1576      2.063894e-03  2.158119e-03  2.256484e-03  2.359159e-03
## ASV1725      1.018128e-03  1.067461e-03  1.119191e-03  1.173432e-03
## ASV4501      5.486810e-04  5.707903e-04  5.936053e-04  6.171316e-04
## ASV10678    -2.702288e-03 -2.827075e-03 -2.957446e-03 -3.093635e-03
## ASV0944      4.272385e-04  4.477199e-04  4.691874e-04  4.916886e-04
## ASV2292      2.190290e-03  2.289153e-03  2.392236e-03  2.499697e-03
## ASV1090      8.814715e-04  9.215242e-04  9.633142e-04  1.006910e-03
## ASV9117     -6.126687e-04 -6.372071e-04 -6.625336e-04 -6.886576e-04
## ASV0285     -1.057501e-03 -1.112682e-03 -1.170873e-03 -1.232244e-03
## ASV0463     -6.215922e-04 -6.484658e-04 -6.763778e-04 -7.053573e-04
## ASV3199      7.893538e-04  8.230664e-04  8.580496e-04  8.943368e-04
## ASV0150     -1.248520e-04 -1.315472e-04 -1.386206e-04 -1.460940e-04
## ASV6583     -6.621716e-04 -6.899828e-04 -7.188263e-04 -7.487315e-04
## ASV0392      6.624291e-05  6.892850e-05  7.170052e-05  7.455966e-05
## ASV14007    -9.832779e-04 -1.027584e-03 -1.073770e-03 -1.121905e-03
## ASV0177     -4.628337e-04 -4.834910e-04 -5.050087e-04 -5.274171e-04
## ASV6448     -7.153768e-04 -7.523711e-04 -7.913614e-04 -8.324587e-04
## ASV5399     -4.378895e-03 -4.592928e-03 -4.817563e-03 -5.053327e-03
## ASV0277     -1.024882e-04 -1.070004e-04 -1.116916e-04 -1.165668e-04
## ASV2599      5.597495e-04  5.726603e-04  5.850603e-04  5.968432e-04
## ASV13465    -3.216835e-04 -3.331948e-04 -3.449445e-04 -3.569214e-04
## ASV2412      2.556476e-04  2.674994e-04  2.798859e-04  2.928299e-04
## ASV0423     -9.269479e-05 -9.588015e-05 -9.910689e-05 -1.023675e-04
## ASV5187      1.331542e-03  1.384639e-03  1.439415e-03  1.495885e-03
## ASV0701     -8.717200e-04 -9.124302e-04 -9.550036e-04 -9.995220e-04
## ASV4248      4.734698e-04  4.970420e-04  5.218133e-04  5.478454e-04
## ASV0519      8.233481e-04  8.623783e-04  9.032405e-04  9.460182e-04
## ASV0764      2.176842e-04  2.281505e-04  2.391192e-04  2.506137e-04
## ASV5385     -7.350065e-04 -7.695946e-04 -8.057917e-04 -8.436710e-04
## ASV3021     -1.256689e-03 -1.308463e-03 -1.362041e-03 -1.417460e-03
## ASV4119     -3.250872e-03 -3.399357e-03 -3.554385e-03 -3.716228e-03
## ASV2534     -1.353492e-04 -1.439554e-04 -1.531434e-04 -1.629528e-04
## ASV1061      8.208551e-04  8.618344e-04  9.049248e-04  9.502393e-04
## ASV0670     -2.205077e-04 -2.307414e-04 -2.414370e-04 -2.526142e-04
## ASV1384      9.555876e-04  1.002785e-03  1.052347e-03  1.104394e-03
## ASV1981      2.314616e-03  2.423953e-03  2.538399e-03  2.658186e-03
## ASV9632     -4.784226e-04 -4.951982e-04 -5.122909e-04 -5.296819e-04
## ASV4564      6.810507e-04  7.126507e-04  7.456738e-04  7.801797e-04
## ASV5289     -4.261278e-04 -4.471036e-04 -4.691401e-04 -4.922933e-04
## ASV0516      1.612554e-03  1.687050e-03  1.764875e-03  1.846169e-03
## ASV1463     -2.262186e-03 -2.366381e-03 -2.475217e-03 -2.588884e-03
## ASV0969      8.734640e-05  9.099416e-05  9.476886e-05  9.867239e-05
## ASV1113     -5.162345e-04 -5.401840e-04 -5.652154e-04 -5.913747e-04
## ASV1234     -6.199060e-04 -6.524114e-04 -6.867345e-04 -7.229852e-04
## ASV3814     -3.708021e-04 -3.953497e-04 -4.216161e-04 -4.497211e-04
## ASV1000      1.033056e-03  1.079650e-03  1.128223e-03  1.178849e-03
## ASV0079     -1.111939e-04 -1.171043e-04 -1.233482e-04 -1.299458e-04
## ASV0145      1.910010e-04  1.981961e-04  2.055791e-04  2.131475e-04
## ASV0457     -1.344660e-03 -1.405726e-03 -1.469430e-03 -1.535875e-03
## ASV1485      1.070054e-04  1.122274e-04  1.177094e-04  1.234648e-04
## ASV0535      4.074287e-04  4.282670e-04  4.502107e-04  4.733199e-04
## ASV0259     -7.502084e-04 -7.846446e-04 -8.205985e-04 -8.581309e-04
## ASV0570      2.295291e-04  2.409974e-04  2.530577e-04  2.657417e-04
## ASV0906      8.617985e-04  9.004380e-04  9.407012e-04  9.826466e-04
## ASV1748      8.408622e-04  8.702562e-04  9.001284e-04  9.304272e-04
## ASV5520     -1.129355e-03 -1.187142e-03 -1.247996e-03 -1.312085e-03
## ASV2288     -2.834655e-03 -2.965665e-03 -3.102549e-03 -3.245552e-03
## ASV1887     -5.764367e-04 -6.083336e-04 -6.420822e-04 -6.777906e-04
## ASV0374     -1.197597e-04 -1.244795e-04 -1.293415e-04 -1.343462e-04
## ASV0823      1.659409e-03  1.733041e-03  1.809715e-03  1.889538e-03
## ASV0717      1.235066e-04  1.292713e-04  1.352985e-04  1.415994e-04
## ASV0431     -3.357037e-04 -3.516188e-04 -3.682839e-04 -3.857339e-04
## ASV1030      3.853722e-03  4.036288e-03  4.227438e-03  4.427567e-03
## ASV1082     -5.024017e-04 -5.259176e-04 -5.505138e-04 -5.762383e-04
## ASV2684      7.623623e-05  8.228272e-05  8.879534e-05  9.580654e-05
## ASV0051      4.790982e-04  5.014624e-04  5.248511e-04  5.493096e-04
## ASV0513     -1.510506e-04 -1.576453e-04 -1.644993e-04 -1.716198e-04
## ASV0581      8.742401e-04  9.148789e-04  9.573572e-04  1.001753e-03
## ASV7282      2.799442e-04  2.954169e-04  3.118134e-04  3.291931e-04
## ASV3009     -7.481045e-04 -7.827947e-04 -8.190493e-04 -8.569345e-04
## ASV2106      8.820455e-04  9.284721e-04  9.774723e-04  1.029195e-03
## ASV1012      6.312016e-04  6.611560e-04  6.925138e-04  7.253379e-04
## ASV0921      6.368562e-04  6.675628e-04  6.997655e-04  7.335382e-04
## ASV0010     -3.741255e-04 -3.916618e-04 -4.100049e-04 -4.291903e-04
## ASV1178      1.697318e-04  1.779418e-04  1.865477e-04  1.955679e-04
## ASV2848     -1.003733e-03 -1.049142e-03 -1.096513e-03 -1.145927e-03
## ASV0586      2.489308e-03  2.607353e-03  2.730971e-03  2.860422e-03
## ASV4225     -3.744668e-03 -3.884956e-03 -4.028868e-03 -4.176358e-03
## ASV2156     -1.399497e-03 -1.465310e-03 -1.534179e-03 -1.606239e-03
## ASV9778     -1.006013e-03 -1.052880e-03 -1.101883e-03 -1.153114e-03
## ASV0493     -2.057592e-03 -2.151002e-03 -2.248459e-03 -2.350122e-03
## ASV3770     -2.455788e-04 -2.609857e-04 -2.774221e-04 -2.949577e-04
## ASV0470      1.435391e-03  1.502221e-03  1.572094e-03  1.645141e-03
## ASV0262     -6.103245e-04 -6.411884e-04 -6.736652e-04 -7.078417e-04
## ASV0998      3.741646e-04  3.918144e-04  4.102887e-04  4.296252e-04
## ASV7708     -1.818215e-04 -1.896208e-04 -1.977129e-04 -2.061045e-04
## ASV0453     -1.476278e-04 -1.544144e-04 -1.615067e-04 -1.689184e-04
## ASV0044      6.009623e-04  6.287045e-04  6.576867e-04  6.879603e-04
## ASV5490      3.451366e-04  3.600287e-04  3.754848e-04  3.915182e-04
## ASV2638     -2.011877e-04 -2.095060e-04 -2.181262e-04 -2.270574e-04
## ASV0829      2.072946e-03  2.168644e-03  2.268579e-03  2.372919e-03
## ASV0601      6.893023e-04  7.222349e-04  7.567415e-04  7.928969e-04
## ASV0234      5.235086e-05  5.502320e-05  5.783928e-05  6.080742e-05
## ASV0133      1.051798e-03  1.100802e-03  1.152038e-03  1.205604e-03
## ASV0323      3.445571e-04  3.611914e-04  3.786382e-04  3.969380e-04
## ASV0854     -2.393354e-04 -2.503437e-04 -2.618407e-04 -2.738467e-04
## ASV0110      6.626933e-04  6.937173e-04  7.261690e-04  7.601119e-04
## ASV0816     -6.556374e-05 -6.869296e-05 -7.197114e-05 -7.540527e-05
## ASV1031     -2.475361e-04 -2.583142e-04 -2.695217e-04 -2.811726e-04
## ASV0144     -3.054912e-04 -3.200531e-04 -3.353112e-04 -3.512990e-04
## ASV0020     -1.418926e-04 -1.488990e-04 -1.562625e-04 -1.640021e-04
## ASV0962     -3.939831e-04 -4.121538e-04 -4.311341e-04 -4.509574e-04
## ASV0794      7.335032e-04  7.695187e-04  8.073285e-04  8.470224e-04
## ASV7117     -6.888001e-04 -7.201867e-04 -7.529395e-04 -7.871123e-04
## ASV1008     -3.312550e-04 -3.471693e-04 -3.638525e-04 -3.813417e-04
## ASV0096      8.483599e-04  8.880434e-04  9.295498e-04  9.729596e-04
## ASV0128     -1.397060e-03 -1.463745e-03 -1.533619e-03 -1.606833e-03
## ASV5232      1.285065e-03  1.347355e-03  1.412690e-03  1.481221e-03
## ASV0031     -9.964812e-05 -1.043666e-04 -1.093063e-04 -1.144774e-04
## ASV1744     -1.356866e-03 -1.420983e-03 -1.488124e-03 -1.558435e-03
## ASV0289      3.824555e-04  4.002934e-04  4.189474e-04  4.384536e-04
## ASV7413     -2.167359e-04 -2.292804e-04 -2.426058e-04 -2.567631e-04
## ASV0822     -1.694107e-03 -1.770641e-03 -1.850446e-03 -1.933645e-03
## ASV8111     -2.800590e-03 -2.926977e-03 -3.058798e-03 -3.196269e-03
## ASV0687      3.630723e-04  3.804357e-04  3.986272e-04  4.176855e-04
## ASV0112     -1.324715e-04 -1.388395e-04 -1.455150e-04 -1.525130e-04
## ASV0987      4.486810e-04  4.702102e-04  4.927785e-04  5.164365e-04
## ASV5332     -2.831854e-04 -2.931407e-04 -3.033068e-04 -3.136784e-04
## ASV1129     -8.250024e-04 -8.635971e-04 -9.039683e-04 -9.461955e-04
## ASV1274     -2.282392e-04 -2.388267e-04 -2.498928e-04 -2.614579e-04
## ASV0119      5.502127e-04  5.759178e-04  6.028009e-04  6.309139e-04
## ASV0890     -2.886828e-05 -3.033742e-05 -3.188755e-05 -3.352381e-05
## ASV0848     -1.021751e-03 -1.069469e-03 -1.119372e-03 -1.171558e-03
## ASV5944     -4.496024e-03 -4.702884e-03 -4.918933e-03 -5.144551e-03
## ASV19741    -1.639137e-03 -1.714893e-03 -1.794046e-03 -1.876740e-03
## ASV0504     -2.068578e-03 -2.162118e-03 -2.259674e-03 -2.361401e-03
## ASV2146     -1.495448e-03 -1.561652e-03 -1.630588e-03 -1.702352e-03
## ASV0089     -3.490819e-04 -3.652706e-04 -3.821886e-04 -3.998667e-04
## ASV2301     -5.657051e-04 -5.923570e-04 -6.202500e-04 -6.494403e-04
## ASV2982     -9.948730e-03 -1.035004e-02 -1.076461e-02 -1.119265e-02
## ASV0891     -6.608189e-04 -6.915173e-04 -7.236061e-04 -7.571449e-04
## ASV0093      7.222926e-04  7.556229e-04  7.904438e-04  8.268180e-04
## ASV0042      2.529557e-04  2.647811e-04  2.771495e-04  2.900847e-04
## ASV0980      8.205756e-04  8.569695e-04  8.948509e-04  9.342689e-04
## ASV0069     -3.862492e-04 -4.042940e-04 -4.231645e-04 -4.428967e-04
## ASV1364     -2.965517e-04 -3.101362e-04 -3.243179e-04 -3.391209e-04
## ASV0524     -1.485431e-03 -1.555633e-03 -1.629126e-03 -1.706063e-03
## ASV0435      2.035610e-03  2.131194e-03  2.231202e-03  2.335833e-03
## ASV0517     -4.017976e-04 -4.206047e-04 -4.402768e-04 -4.608525e-04
## ASV3167     -2.894998e-03 -3.040256e-03 -3.193019e-03 -3.353682e-03
## ASV4280     -1.837889e-03 -1.923365e-03 -2.012725e-03 -2.106138e-03
## ASV1158      6.518653e-04  6.844935e-04  7.187804e-04  7.548092e-04
## ASV2214      6.158422e-04  6.434034e-04  6.721416e-04  7.021044e-04
## ASV0544     -9.980704e-04 -1.045617e-03 -1.095428e-03 -1.147609e-03
## ASV5326     -1.392545e-04 -1.460092e-04 -1.530973e-04 -1.605358e-04
## ASV3765     -7.779553e-04 -8.140291e-04 -8.517295e-04 -8.911257e-04
## ASV4646      7.633244e-06  5.408896e-06  2.866746e-06 -2.379910e-08
## ASV0090      6.077229e-05  6.330085e-05  6.591658e-05  6.862073e-05
## ASV3680      1.288546e-03  1.345250e-03  1.404237e-03  1.465582e-03
## ASV0111      1.352890e-04  1.413634e-04  1.476936e-04  1.542889e-04
## ASV0768      1.933404e-04  2.027011e-04  2.125216e-04  2.228250e-04
## ASV4862     -1.114764e-04 -1.156144e-04 -1.198406e-04 -1.241492e-04
## ASV1742     -1.134255e-03 -1.185794e-03 -1.239575e-03 -1.295686e-03
## ASV3701     -4.226399e-04 -4.400955e-04 -4.581633e-04 -4.768560e-04
## ASV2386     -2.157101e-03 -2.259129e-03 -2.365930e-03 -2.477722e-03
## ASV0375     -1.527088e-03 -1.596754e-03 -1.669474e-03 -1.745373e-03
## ASV2796      5.274476e-04  5.503910e-04  5.742483e-04  5.990500e-04
## ASV1369      1.182424e-03  1.235026e-03  1.289844e-03  1.346967e-03
## ASV10272    -1.725987e-03 -1.805795e-03 -1.889178e-03 -1.976284e-03
## ASV10354    -2.570285e-03 -2.689121e-03 -2.813279e-03 -2.942979e-03
## ASV1067      8.421735e-04  8.807432e-04  9.210126e-04  9.630508e-04
## ASV1900      1.381759e-03  1.446618e-03  1.514477e-03  1.585470e-03
## ASV4079     -6.297095e-04 -6.608790e-04 -6.936272e-04 -7.280357e-04
## ASV4149      2.716499e-03  2.837148e-03  2.962758e-03  3.093498e-03
## ASV5140     -2.570120e-03 -2.688940e-03 -2.813080e-03 -2.942761e-03
## ASV10782     8.781395e-05  9.376937e-05  1.001745e-04  1.070659e-04
## ASV4273     -2.449695e-04 -2.546362e-04 -2.645746e-04 -2.747801e-04
## ASV8121      1.157197e-03  1.211055e-03  1.267366e-03  1.326236e-03
## ASV8438     -2.923989e-03 -3.059160e-03 -3.200382e-03 -3.347907e-03
## ASV9390     -2.923707e-03 -3.058852e-03 -3.200044e-03 -3.347537e-03
## ASV1340      2.357515e-03  2.468178e-03  2.583956e-03  2.705078e-03
## ASV2650     -5.434018e-03 -5.683654e-03 -5.944323e-03 -6.216471e-03
## ASV4674      1.450434e-03  1.517123e-03  1.586764e-03  1.659479e-03
## ASV10492     2.327229e-05  2.366915e-05  2.401941e-05  2.431502e-05
## ASV11430    -2.231044e-03 -2.334157e-03 -2.441884e-03 -2.554416e-03
## ASV12135    -2.230829e-03 -2.333922e-03 -2.441626e-03 -2.554134e-03
## ASV14970    -2.743269e-03 -2.870031e-03 -3.002462e-03 -3.140797e-03
## ASV1954      3.333197e-03  3.487693e-03  3.649148e-03  3.817858e-03
## ASV2613      2.107830e-03  2.204962e-03  2.306418e-03  2.412379e-03
## ASV2757      1.308203e-03  1.366426e-03  1.427057e-03  1.490179e-03
## ASV2909     -3.924885e-03 -4.110685e-03 -4.305223e-03 -4.508904e-03
## ASV2954     -1.475760e-04 -1.544467e-04 -1.616279e-04 -1.691327e-04
## ASV2969      1.003321e-03  1.050510e-03  1.099890e-03  1.151560e-03
## ASV3410      3.555933e-04  3.726082e-04  3.904421e-04  4.091349e-04
## ASV3575      6.794962e-04  7.104447e-04  7.427429e-04  7.764445e-04
## ASV4275      1.741846e-03  1.820080e-03  1.901610e-03  1.986555e-03
## ASV4652      3.756000e-04  3.934547e-04  4.121560e-04  4.317437e-04
## ASV4761      1.262554e-03  1.319124e-03  1.378062e-03  1.439449e-03
## ASV6003      9.272649e-04  9.718076e-04  1.018506e-03  1.067466e-03
## ASV6110     -6.294871e-03 -6.585806e-03 -6.889759e-03 -7.207270e-03
## ASV7427      1.093009e-03  1.142761e-03  1.194672e-03  1.248826e-03
## ASV8092     -2.064205e-03 -2.159602e-03 -2.259266e-03 -2.363375e-03
## ASV8169     -6.293866e-03 -6.584706e-03 -6.888554e-03 -7.205951e-03
## ASV9693      1.067840e-03  1.116958e-03  1.168253e-03  1.221813e-03
## ASV10913     7.179256e-04  7.517420e-04  7.871333e-04  8.241710e-04
## ASV1979      6.339708e-04  6.627051e-04  6.926716e-04  7.239165e-04
## ASV3772      1.309724e-03  1.369006e-03  1.430832e-03  1.495300e-03
## ASV0113     -1.760150e-04 -1.843015e-04 -1.929726e-04 -2.020453e-04
## ASV1800     -2.325816e-04 -2.436026e-04 -2.551385e-04 -2.672123e-04
## ASV2335     -4.832909e-03 -5.053518e-03 -5.283825e-03 -5.524227e-03
## ASV0692     -3.275672e-05 -3.436718e-05 -3.606005e-05 -3.783994e-05
## ASV1120      1.746661e-04  1.829801e-04  1.916898e-04  2.008140e-04
## ASV1434     -8.673599e-04 -9.079344e-04 -9.503729e-04 -9.947579e-04
## ASV0076     -4.063900e-04 -4.253533e-04 -4.451821e-04 -4.659142e-04
## ASV0361      1.451358e-03  1.519475e-03  1.590744e-03  1.665304e-03
## ASV2231     -4.681542e-04 -4.913831e-04 -5.158009e-04 -5.414711e-04
## ASV2018     -1.165668e-04 -1.220061e-04 -1.276947e-04 -1.336438e-04
## ASV1529      6.291298e-04  6.591185e-04  6.905369e-04  7.234531e-04
## ASV0841     -2.192956e-04 -2.294225e-04 -2.400026e-04 -2.510547e-04
## ASV2556     -4.025570e-03 -4.213032e-03 -4.409019e-03 -4.613900e-03
## ASV2777      1.329968e-03  1.387853e-03  1.448005e-03  1.510491e-03
## ASV0355      1.002938e-03  1.049524e-03  1.098220e-03  1.149118e-03
## ASV5169     -1.199339e-03 -1.254853e-03 -1.312861e-03 -1.373466e-03
## ASV3091      1.130904e-03  1.184356e-03  1.240315e-03  1.298898e-03
## ASV2435      4.567389e-04  4.778001e-04  4.997994e-04  5.227756e-04
## ASV6822     -2.472120e-03 -2.586403e-03 -2.705801e-03 -2.830528e-03
## ASV12605    -2.408355e-03 -2.521217e-03 -2.639278e-03 -2.762771e-03
## ASV0286     -5.782042e-04 -6.049958e-04 -6.330010e-04 -6.622729e-04
## ASV0074     -2.285950e-04 -2.393566e-04 -2.506177e-04 -2.624009e-04
## ASV2485     -9.647348e-05 -1.016792e-04 -1.071950e-04 -1.130419e-04
## ASV1233     -1.808607e-03 -1.893481e-03 -1.982282e-03 -2.075188e-03
## ASV0356     -4.789059e-04 -5.008207e-04 -5.237020e-04 -5.475894e-04
## ASV2918     -2.013610e-03 -2.106668e-03 -2.203899e-03 -2.305477e-03
## ASV1427     -2.525126e-04 -2.648027e-04 -2.777036e-04 -2.912467e-04
## ASV1409      4.445304e-04  4.657287e-04  4.879383e-04  5.112075e-04
## ASV0770      1.392833e-04  1.454687e-04  1.519074e-04  1.586079e-04
## ASV1403     -1.240266e-03 -1.297836e-03 -1.358008e-03 -1.420895e-03
## ASV0314     -4.297590e-04 -4.492897e-04 -4.696619e-04 -4.909072e-04
## ASV0187     -1.263632e-04 -1.324149e-04 -1.387548e-04 -1.453962e-04
## ASV0313     -6.107514e-04 -6.387594e-04 -6.680007e-04 -6.985249e-04
## ASV1087      1.408095e-03  1.473586e-03  1.542051e-03  1.613618e-03
## ASV1970     -2.140526e-04 -2.239486e-04 -2.342870e-04 -2.450861e-04
## ASV0754      1.550057e-03  1.622516e-03  1.698299e-03  1.777554e-03
## ASV3775     -3.705496e-04 -3.880154e-04 -4.062957e-04 -4.254277e-04
## ASV0132     -2.672752e-04 -2.797372e-04 -2.927679e-04 -3.063921e-04
## ASV2329      1.463206e-04  1.501053e-04  1.538065e-04  1.574006e-04
## ASV0561      3.941877e-04  4.117500e-04  4.300339e-04  4.490629e-04
## ASV0130     -8.076321e-04 -8.453779e-04 -8.848525e-04 -9.261316e-04
## ASV0226      1.017673e-03  1.064855e-03  1.114163e-03  1.165688e-03
## ASV12648    -1.427210e-03 -1.492381e-03 -1.560418e-03 -1.631439e-03
## ASV0204      9.793531e-04  1.024767e-03  1.072229e-03  1.121825e-03
## ASV0767     -4.751496e-04 -4.982449e-04 -5.224837e-04 -5.479247e-04
## ASV0335     -9.117498e-04 -9.538918e-04 -9.979196e-04 -1.043912e-03
## ASV5901     -1.996415e-04 -2.084737e-04 -2.176716e-04 -2.272486e-04
## ASV0596      1.504057e-07  8.653920e-07  1.678982e-06  2.601537e-06
## ASV9271      7.379707e-04  7.751000e-04  8.141491e-04  8.552189e-04
## ASV0904      5.911218e-04  6.191689e-04  6.485407e-04  6.792992e-04
## ASV15270    -3.873405e-04 -4.072506e-04 -4.282195e-04 -4.503043e-04
## ASV0990     -3.266677e-04 -3.420742e-04 -3.582001e-04 -3.750785e-04
## ASV0155     -6.778806e-04 -7.094089e-04 -7.423677e-04 -7.768186e-04
## ASV0086     -1.352377e-04 -1.415472e-04 -1.481448e-04 -1.550432e-04
## ASV2581     -6.519657e-05 -6.799865e-05 -7.090483e-05 -7.391726e-05
## ASV1579     -5.546471e-04 -5.810710e-04 -6.087519e-04 -6.377494e-04
## ASV7730     -3.172879e-05 -3.448189e-05 -3.745729e-05 -4.067070e-05
## ASV0897      8.315284e-05  8.720569e-05  9.145962e-05  9.592488e-05
## ASV1975      3.795905e-03  3.972700e-03  4.157552e-03  4.350813e-03
##                                                                    
## (Intercept)  1.415321e-02  1.481054e-02  1.549753e-02  1.621544e-02
## ASV1236      2.278722e-03  2.381105e-03  2.487800e-03  2.598963e-03
## ASV0421     -1.076812e-03 -1.124754e-03 -1.174678e-03 -1.226650e-03
## ASV0691     -2.195362e-03 -2.289414e-03 -2.387018e-03 -2.488265e-03
## ASV0899      1.335754e-03  1.398283e-03  1.463671e-03  1.532041e-03
## ASV1004      5.136232e-03  5.367913e-03  5.609441e-03  5.861181e-03
## ASV1041     -3.143973e-03 -3.286951e-03 -3.436103e-03 -3.591664e-03
## ASV1058      3.200620e-03  3.345059e-03  3.495651e-03  3.652623e-03
## ASV12542     1.204512e-03  1.257915e-03  1.313510e-03  1.371372e-03
## ASV1294      2.693796e-03  2.815893e-03  2.943237e-03  3.076027e-03
## ASV13113     9.648289e-04  1.010986e-03  1.059362e-03  1.110064e-03
## ASV1318      2.949030e-03  3.082446e-03  3.221568e-03  3.366610e-03
## ASV2269     -5.014311e-03 -5.242753e-03 -5.481064e-03 -5.729617e-03
## ASV2542      2.219063e-03  2.322929e-03  2.431567e-03  2.545188e-03
## ASV2660     -2.227706e-03 -2.328147e-03 -2.432845e-03 -2.541955e-03
## ASV2737      4.072610e-04  4.240611e-04  4.414426e-04  4.594163e-04
## ASV2840      2.791600e-03  2.915859e-03  3.045244e-03  3.179930e-03
## ASV3053      2.355090e-02  2.460725e-02  2.570803e-02  2.685483e-02
## ASV3077      8.293964e-04  8.664921e-04  9.051436e-04  9.454072e-04
## ASV3134      1.600998e-03  1.676670e-03  1.755894e-03  1.838834e-03
## ASV3140      1.945994e-03  2.036256e-03  2.130575e-03  2.229121e-03
## ASV3579      6.388010e-04  6.696922e-04  7.020992e-04  7.360981e-04
## ASV6119     -1.368512e-03 -1.430849e-03 -1.495879e-03 -1.563702e-03
## ASV7557     -2.783738e-03 -2.910525e-03 -3.042786e-03 -3.180728e-03
## ASV8422      6.094575e-04  6.359473e-04  6.634823e-04  6.920952e-04
## ASV1086     -1.449705e-04 -1.511299e-04 -1.575229e-04 -1.641562e-04
## ASV1310      1.185730e-03  1.239198e-03  1.294938e-03  1.353034e-03
## ASV15750    -2.031188e-04 -2.121839e-04 -2.216186e-04 -2.314344e-04
## ASV16905    -5.714836e-04 -5.975114e-04 -6.246629e-04 -6.529806e-04
## ASV2033      2.521066e-03  2.638431e-03  2.761133e-03  2.889404e-03
## ASV2089      1.045199e-03  1.092944e-03  1.142761e-03  1.194728e-03
## ASV2127      3.946675e-03  4.124551e-03  4.309977e-03  4.503234e-03
## ASV2725      3.158743e-03  3.299411e-03  3.445898e-03  3.598403e-03
## ASV2804     -1.183544e-03 -1.237445e-03 -1.293673e-03 -1.352316e-03
## ASV3075      2.653778e-03  2.774275e-03  2.899986e-03  3.031116e-03
## ASV3327      3.626596e-03  3.795081e-03  3.971204e-03  4.155294e-03
## ASV3342      2.986224e-03  3.124322e-03  3.268603e-03  3.419323e-03
## ASV3532     -3.399207e-03 -3.556846e-03 -3.721576e-03 -3.893696e-03
## ASV3600      1.531123e-03  1.601317e-03  1.674609e-03  1.751124e-03
## ASV4013      2.955652e-03  3.089682e-03  3.229482e-03  3.375271e-03
## ASV4136      3.246415e-03  3.391177e-03  3.541939e-03  3.698910e-03
## ASV4195      1.196295e-02  1.250769e-02  1.307593e-02  1.366858e-02
## ASV4407     -4.679289e-03 -4.892337e-03 -5.114577e-03 -5.346356e-03
## ASV4717      4.516839e-04  4.692613e-04  4.873527e-04  5.059588e-04
## ASV6794      1.829406e-03  1.908673e-03  1.991034e-03  2.076580e-03
## ASV8324     -2.396935e-03 -2.506064e-03 -2.619902e-03 -2.738625e-03
## ASV8981     -8.228942e-05 -8.555899e-05 -8.892061e-05 -9.237261e-05
## ASV9859      7.340195e-04  7.702527e-04  8.083344e-04  8.483639e-04
## ASV0936      1.895840e-04  1.993554e-04  2.096418e-04  2.204701e-04
## ASV12683    -5.960145e-05 -6.292398e-05 -6.643705e-05 -7.015115e-05
## ASV1293      1.506203e-03  1.573951e-03  1.644559e-03  1.718132e-03
## ASV13055    -8.085172e-05 -8.412734e-05 -8.749751e-05 -9.096031e-05
## ASV17063    -1.242451e-03 -1.299001e-03 -1.357988e-03 -1.419506e-03
## ASV2228      1.011477e-03  1.057508e-03  1.105523e-03  1.155598e-03
## ASV2769      1.017515e-04  1.066911e-04  1.118790e-04  1.173284e-04
## ASV2803      8.968622e-04  9.356760e-04  9.760000e-04  1.017879e-03
## ASV2896      8.431457e-04  8.821228e-04  9.228559e-04  9.654207e-04
## ASV3062      9.091606e-04  9.523113e-04  9.975079e-04  1.044847e-03
## ASV3107      1.689539e-03  1.767847e-03  1.849691e-03  1.935221e-03
## ASV3265      2.324390e-03  2.428921e-03  2.537869e-03  2.651394e-03
## ASV3666      8.111356e-06  8.312576e-06  8.513112e-06  8.712726e-06
## ASV4497      7.076845e-04  7.396981e-04  7.730885e-04  8.079089e-04
## ASV6914     -1.701630e-04 -1.785919e-04 -1.874426e-04 -1.967360e-04
## ASV0576     -2.983717e-03 -3.114097e-03 -3.249647e-03 -3.390526e-03
## ASV0673      2.222732e-03  2.325369e-03  2.432590e-03  2.544585e-03
## ASV0772      1.281945e-03  1.340173e-03  1.400925e-03  1.464298e-03
## ASV0862     -2.050684e-04 -2.126220e-04 -2.203477e-04 -2.282388e-04
## ASV0898      9.363831e-04  9.805921e-04  1.026861e-03  1.075282e-03
## ASV0910      1.155807e-03  1.209700e-03  1.266052e-03  1.324971e-03
## ASV0964     -1.190320e-03 -1.243318e-03 -1.298516e-03 -1.355992e-03
## ASV10059     8.207892e-04  8.600135e-04  9.011226e-04  9.442081e-04
## ASV10263    -1.893020e-03 -1.979234e-03 -2.069170e-03 -2.162968e-03
## ASV1088      1.858620e-03  1.944979e-03  2.035262e-03  2.129640e-03
## ASV1101      2.200499e-03  2.299806e-03  2.403338e-03  2.511252e-03
## ASV1183      6.694921e-04  7.005683e-04  7.330436e-04  7.669767e-04
## ASV11956     5.859999e-04  6.105493e-04  6.359836e-04  6.623226e-04
## ASV12774    -1.105022e-05 -1.239590e-05 -1.387162e-05 -1.548834e-05
## ASV1321      2.879756e-03  3.014237e-03  3.154879e-03  3.301953e-03
## ASV13793    -1.304601e-03 -1.364010e-03 -1.425984e-03 -1.490620e-03
## ASV14482     1.323754e-05  1.292337e-05  1.252120e-05  1.202204e-05
## ASV15483     4.836616e-04  5.061080e-04  5.295744e-04  5.541056e-04
## ASV2062      2.413900e-03  2.523910e-03  2.638705e-03  2.758474e-03
## ASV2132      2.102044e-03  2.199935e-03  2.302286e-03  2.409291e-03
## ASV2413      1.901415e-03  1.986823e-03  2.075837e-03  2.168588e-03
## ASV2490      5.893886e-03  6.153941e-03  6.424523e-03  6.705975e-03
## ASV2594      6.861847e-04  7.174294e-04  7.500408e-04  7.840747e-04
## ASV2822     -3.448108e-03 -3.605166e-03 -3.769006e-03 -3.939886e-03
## ASV2863      3.732557e-03  3.899431e-03  4.073258e-03  4.254281e-03
## ASV2910      1.294263e-03  1.352132e-03  1.412417e-03  1.475207e-03
## ASV2980      1.254609e-03  1.311981e-03  1.371853e-03  1.434324e-03
## ASV3307      2.730983e-03  2.855349e-03  2.985083e-03  3.120389e-03
## ASV3474      1.658091e-03  1.735882e-03  1.817270e-03  1.902416e-03
## ASV3502      2.001727e-03  2.093621e-03  2.189577e-03  2.289760e-03
## ASV4236      2.908886e-03  3.038702e-03  3.173912e-03  3.314707e-03
## ASV4842     -5.700119e-04 -5.976409e-04 -6.265982e-04 -6.569441e-04
## ASV4894     -1.304785e-03 -1.364212e-03 -1.426206e-03 -1.490862e-03
## ASV5290      1.036879e-03  1.084532e-03  1.134300e-03  1.186271e-03
## ASV5501      5.179978e-04  5.416692e-04  5.663885e-04  5.921999e-04
## ASV5795      6.340005e-04  6.631927e-04  6.936875e-04  7.255398e-04
## ASV5987     -3.650720e-03 -3.817009e-03 -3.990479e-03 -4.171403e-03
## ASV6267     -4.114828e-03 -4.302233e-03 -4.497731e-03 -4.701627e-03
## ASV6862      1.684724e-03  1.758845e-03  1.835953e-03  1.916145e-03
## ASV7145      6.324324e-04  6.589365e-04  6.863987e-04  7.148412e-04
## ASV7673     -1.304694e-03 -1.364113e-03 -1.426097e-03 -1.490743e-03
## ASV7789      5.491550e-04  5.756798e-04  6.035057e-04  6.326984e-04
## ASV7809     -2.529600e-05 -2.602872e-05 -2.674758e-05 -2.744708e-05
## ASV8002     -1.648152e-03 -1.723209e-03 -1.801506e-03 -1.883166e-03
## ASV8205      5.550102e-04  5.801168e-04  6.063085e-04  6.336284e-04
## ASV9155     -4.532018e-04 -4.736819e-04 -4.950278e-04 -5.172700e-04
## ASV9221      4.044640e-05  4.209525e-05  4.380315e-05  4.557177e-05
## ASV9311     -2.645738e-03 -2.766211e-03 -2.891883e-03 -3.022952e-03
## ASV9557     -1.806947e-03 -1.889216e-03 -1.975035e-03 -2.064538e-03
## ASV9936     -3.648735e-03 -3.814839e-03 -3.988109e-03 -4.168814e-03
## ASV1445      2.390727e-03  2.500926e-03  2.616038e-03  2.736267e-03
## ASV4232      1.059105e-03  1.108895e-03  1.161001e-03  1.215530e-03
## ASV6479      1.618645e-04  1.713558e-04  1.814681e-04  1.922464e-04
## ASV0142     -1.510670e-03 -1.578140e-03 -1.648420e-03 -1.721610e-03
## ASV0378     -6.453620e-05 -6.624911e-05 -6.792035e-05 -6.953713e-05
## ASV1122      2.352749e-03  2.461557e-03  2.575251e-03  2.694035e-03
## ASV0123     -1.336792e-03 -1.396420e-03 -1.458526e-03 -1.523194e-03
## ASV2064      7.657914e-04  7.989178e-04  8.333414e-04  8.691022e-04
## ASV4459     -3.397591e-04 -3.557685e-04 -3.725151e-04 -3.900306e-04
## ASV0448      5.086029e-04  5.330181e-04  5.586077e-04  5.854282e-04
## ASV0397      1.092978e-03  1.143318e-03  1.195896e-03  1.250801e-03
## ASV0485      1.432597e-03  1.497614e-03  1.565434e-03  1.636164e-03
## ASV1566      2.274213e-03  2.378329e-03  2.487019e-03  2.600468e-03
## ASV1365      1.455130e-03  1.521110e-03  1.589931e-03  1.661703e-03
## ASV1065      2.730914e-03  2.856544e-03  2.987747e-03  3.124751e-03
## ASV0722     -1.575245e-04 -1.648495e-04 -1.725126e-04 -1.805297e-04
## ASV12660    -1.498407e-03 -1.565607e-03 -1.635622e-03 -1.708551e-03
## ASV0223      2.294525e-04  2.399826e-04  2.509757e-04  2.624502e-04
## ASV0229      5.692606e-04  5.958700e-04  6.236967e-04  6.527941e-04
## ASV0877      5.349233e-05  5.506057e-05  5.662911e-05  5.819318e-05
## ASV0983      1.451572e-03  1.516989e-03  1.585180e-03  1.656245e-03
## ASV0626     -1.086050e-04 -1.118604e-04 -1.150995e-04 -1.183070e-04
## ASV4146     -8.038054e-05 -8.446716e-05 -8.876824e-05 -9.329545e-05
## ASV4175     -1.748777e-03 -1.829554e-03 -1.913936e-03 -2.002073e-03
## ASV2082     -8.206469e-04 -8.607811e-04 -9.029302e-04 -9.471998e-04
## ASV2272      7.948532e-04  8.310376e-04  8.687972e-04  9.081947e-04
## ASV2245     -1.273853e-03 -1.332788e-03 -1.394361e-03 -1.458682e-03
## ASV0590     -1.057178e-03 -1.109022e-03 -1.163474e-03 -1.220671e-03
## ASV0217     -1.331632e-04 -1.368396e-04 -1.404564e-04 -1.439913e-04
## ASV0416      9.922968e-04  1.035375e-03  1.080124e-03  1.126591e-03
## ASV1056      1.131153e-03  1.184280e-03  1.239867e-03  1.298025e-03
## ASV7777     -1.702794e-03 -1.782198e-03 -1.865222e-03 -1.952022e-03
## ASV0455      2.160457e-04  2.259377e-04  2.362606e-04  2.470308e-04
## ASV0604      6.876012e-04  7.205233e-04  7.550257e-04  7.911839e-04
## ASV6100     -1.207810e-03 -1.264207e-03 -1.323180e-03 -1.384843e-03
## ASV11359    -2.700720e-03 -2.824302e-03 -2.953287e-03 -3.087888e-03
## ASV6604      4.851081e-04  5.079582e-04  5.318742e-04  5.569047e-04
## ASV5004     -7.695091e-04 -8.052238e-04 -8.425486e-04 -8.815515e-04
## ASV1483     -4.844129e-04 -5.071450e-04 -5.309229e-04 -5.557924e-04
## ASV9773     -1.205292e-03 -1.261245e-03 -1.319724e-03 -1.380837e-03
## ASV4059      8.905881e-04  9.337034e-04  9.789375e-04  1.026397e-03
## ASV1193      1.466569e-03  1.533706e-03  1.603793e-03  1.676950e-03
## ASV4610     -2.019349e-04 -2.094264e-04 -2.170832e-04 -2.248970e-04
## ASV0742     -3.298900e-04 -3.432247e-04 -3.569820e-04 -3.711638e-04
## ASV1502      3.757593e-05  3.808579e-05  3.850998e-05  3.883561e-05
## ASV0195     -5.212014e-05 -5.510965e-05 -5.828745e-05 -6.166639e-05
## ASV1213      1.255975e-03  1.311767e-03  1.369849e-03  1.430296e-03
## ASV1648     -1.131267e-03 -1.184005e-03 -1.239145e-03 -1.296792e-03
## ASV6984     -1.053481e-03 -1.102557e-03 -1.153863e-03 -1.207497e-03
## ASV0396     -1.178325e-04 -1.213046e-04 -1.247600e-04 -1.281835e-04
## ASV4297      1.762515e-03  1.840967e-03  1.922667e-03  2.007727e-03
## ASV2622      2.317281e-03  2.421422e-03  2.529962e-03  2.643061e-03
## ASV3512      7.970149e-04  8.351484e-04  8.751151e-04  9.170040e-04
## ASV2411      1.415593e-03  1.481831e-03  1.551106e-03  1.623551e-03
## ASV2291     -7.439673e-04 -7.810320e-04 -8.200154e-04 -8.610226e-04
## ASV0807      1.633885e-03  1.710696e-03  1.791057e-03  1.875124e-03
## ASV1292      5.441689e-04  5.683794e-04  5.935857e-04  6.198214e-04
## ASV1035      1.560811e-03  1.630487e-03  1.703056e-03  1.778619e-03
## ASV0070     -5.572671e-05 -5.755809e-05 -5.940363e-05 -6.125781e-05
## ASV0255      1.482100e-04  1.544926e-04  1.610002e-04  1.677364e-04
## ASV0057     -5.776653e-04 -6.030482e-04 -6.294486e-04 -6.568982e-04
## ASV0077     -9.919027e-05 -1.031624e-04 -1.072574e-04 -1.114755e-04
## ASV0625      1.128714e-03  1.178921e-03  1.231197e-03  1.285610e-03
## ASV2464      7.544584e-03  7.880538e-03  8.230359e-03  8.594519e-03
## ASV1315      2.234701e-03  2.337872e-03  2.445677e-03  2.558313e-03
## ASV2673      1.911397e-03  2.001658e-03  2.096145e-03  2.195051e-03
## ASV2161      8.214409e-04  8.600780e-04  9.005129e-04  9.428278e-04
## ASV0337     -4.408068e-04 -4.611997e-04 -4.825099e-04 -5.047764e-04
## ASV7680     -2.745407e-03 -2.873363e-03 -3.007144e-03 -3.147003e-03
## ASV0611      1.438318e-03  1.505372e-03  1.575484e-03  1.648789e-03
## ASV3118     -1.706234e-03 -1.786795e-03 -1.871116e-03 -1.959367e-03
## ASV1284      1.095893e-03  1.147004e-03  1.200394e-03  1.256149e-03
## ASV0889      1.044878e-03  1.091934e-03  1.140991e-03  1.192124e-03
## ASV4649     -5.827702e-04 -6.097009e-04 -6.378360e-04 -6.672254e-04
## ASV1108     -1.317197e-03 -1.380024e-03 -1.445844e-03 -1.514799e-03
## ASV0738      2.960441e-04  3.128866e-04  3.307732e-04  3.497738e-04
## ASV0473     -1.231590e-04 -1.296060e-04 -1.364133e-04 -1.436026e-04
## ASV0598     -7.804685e-04 -8.151598e-04 -8.512828e-04 -8.888871e-04
## ASV0429      1.115606e-03  1.166004e-03  1.218549e-03  1.273321e-03
## ASV1549      1.451459e-03  1.520253e-03  1.592289e-03  1.667717e-03
## ASV1203      1.221815e-03  1.277035e-03  1.334613e-03  1.394636e-03
## ASV4532      1.750328e-05  1.764891e-05  1.774383e-05  1.778123e-05
## ASV0274     -1.895914e-04 -1.970795e-04 -2.047941e-04 -2.127360e-04
## ASV0163     -1.024670e-03 -1.070138e-03 -1.117473e-03 -1.166737e-03
## ASV1298      4.204676e-04  4.388912e-04  4.580506e-04  4.779692e-04
## ASV9424     -2.367633e-03 -2.478360e-03 -2.594167e-03 -2.715279e-03
## ASV0412      2.042357e-03  2.134839e-03  2.231286e-03  2.331848e-03
## ASV0284      5.100098e-04  5.319393e-04  5.546993e-04  5.783110e-04
## ASV0620     -5.453004e-04 -5.722990e-04 -6.006704e-04 -6.304867e-04
## ASV0153     -1.639813e-03 -1.717258e-03 -1.798329e-03 -1.883192e-03
## ASV0498      6.282485e-04  6.583000e-04  6.897807e-04  7.227568e-04
## ASV0097      4.242226e-04  4.441982e-04  4.651046e-04  4.869844e-04
## ASV0104     -2.821927e-03 -2.950862e-03 -3.085444e-03 -3.225901e-03
## ASV1282      7.431590e-04  7.774753e-04  8.133086e-04  8.507183e-04
## ASV3883     -8.379633e-04 -8.780067e-04 -9.199599e-04 -9.639129e-04
## ASV0801      5.355779e-04  5.612129e-04  5.880742e-04  6.162196e-04
## ASV1611     -1.933291e-03 -2.023795e-03 -2.118458e-03 -2.217465e-03
## ASV0227     -4.098408e-04 -4.298668e-04 -4.508899e-04 -4.729606e-04
## ASV0833      5.569620e-04  5.829326e-04  6.100873e-04  6.384774e-04
## ASV0718      2.726596e-03  2.852687e-03  2.984433e-03  3.122072e-03
## ASV1139      3.767463e-04  3.922323e-04  4.082321e-04  4.247506e-04
## ASV0766     -4.691234e-04 -4.915518e-04 -5.150533e-04 -5.396792e-04
## ASV2091      2.841061e-03  2.966892e-03  3.097873e-03  3.234179e-03
## ASV1238     -1.008959e-03 -1.051456e-03 -1.095535e-03 -1.141242e-03
## ASV9193     -3.599586e-04 -3.812351e-04 -4.038415e-04 -4.278613e-04
## ASV0290      5.406776e-05  5.575649e-05  5.744951e-05  5.914102e-05
## ASV0231      8.934225e-04  9.339553e-04  9.762323e-04  1.020320e-03
## ASV0185      3.345604e-04  3.520455e-04  3.704972e-04  3.899722e-04
## ASV2330      8.308871e-04  8.673464e-04  9.052598e-04  9.446722e-04
## ASV3119     -4.591895e-04 -4.821529e-04 -5.063048e-04 -5.317096e-04
## ASV2368     -1.203992e-03 -1.261118e-03 -1.320944e-03 -1.383593e-03
## ASV0122     -3.994624e-04 -4.173099e-04 -4.359032e-04 -4.552692e-04
## ASV1044      1.292550e-03  1.354084e-03  1.418541e-03  1.486061e-03
## ASV0160     -6.720722e-04 -7.013915e-04 -7.318695e-04 -7.635416e-04
## ASV0326      1.915744e-04  2.003729e-04  2.095604e-04  2.191528e-04
## ASV1388      3.355551e-03  3.508608e-03  3.668337e-03  3.835002e-03
## ASV0792      2.036594e-03  2.128368e-03  2.224035e-03  2.323737e-03
## ASV0036     -5.313438e-04 -5.563527e-04 -5.825243e-04 -6.099112e-04
## ASV2125      1.859113e-03  1.943683e-03  2.031918e-03  2.123959e-03
## ASV1075      8.791088e-05  9.211443e-05  9.652081e-05  1.011400e-04
## ASV0390      9.954672e-04  1.043249e-03  1.093336e-03  1.145843e-03
## ASV3790     -1.521922e-03 -1.592242e-03 -1.665716e-03 -1.742475e-03
## ASV1535     -2.748537e-04 -2.894521e-04 -3.048695e-04 -3.211541e-04
## ASV0263      1.381711e-03  1.445053e-03  1.511180e-03  1.580205e-03
## ASV0675      2.652115e-03  2.776581e-03  2.906792e-03  3.043004e-03
## ASV3348      2.798729e-04  2.934622e-04  3.077227e-04  3.226885e-04
## ASV0058     -8.930834e-04 -9.332216e-04 -9.750577e-04 -1.018655e-03
## ASV4142      1.071385e-03  1.119683e-03  1.170034e-03  1.222513e-03
## ASV0059     -7.392893e-04 -7.723332e-04 -8.067580e-04 -8.426131e-04
## ASV0013     -1.015933e-03 -1.062530e-03 -1.111184e-03 -1.161980e-03
## ASV0033     -5.057967e-04 -5.296397e-04 -5.545944e-04 -5.807116e-04
## ASV4354     -6.791697e-04 -7.105464e-04 -7.433296e-04 -7.775784e-04
## ASV0022     -3.995544e-04 -4.184296e-04 -4.381887e-04 -4.588724e-04
## ASV0134     -4.324597e-04 -4.531618e-04 -4.748593e-04 -4.976002e-04
## ASV0415      3.977481e-05  4.294962e-05  4.638173e-05  5.009131e-05
## ASV10103    -2.399435e-03 -2.511639e-03 -2.628986e-03 -2.751703e-03
## ASV1613      1.851810e-03  1.934971e-03  2.021634e-03  2.111924e-03
## ASV0135     -3.028518e-04 -3.159412e-04 -3.295318e-04 -3.436367e-04
## ASV0469     -2.340170e-03 -2.445647e-03 -2.555608e-03 -2.670221e-03
## ASV0471      1.706797e-03  1.786376e-03  1.869569e-03  1.956531e-03
## ASV0451     -2.503208e-04 -2.632359e-04 -2.768561e-04 -2.912228e-04
## ASV0747      5.977978e-04  6.261117e-04  6.557526e-04  6.867809e-04
## ASV1314     -7.472933e-04 -7.830126e-04 -8.204429e-04 -8.596661e-04
## ASV0425     -3.360319e-03 -3.508973e-03 -3.663700e-03 -3.824708e-03
## ASV0559     -9.509000e-04 -9.937169e-04 -1.038358e-03 -1.084892e-03
## ASV0148     -5.354010e-04 -5.584942e-04 -5.824735e-04 -6.073630e-04
## ASV0129     -1.676992e-04 -1.731595e-04 -1.786614e-04 -1.841891e-04
## ASV1072      3.769789e-04  3.930636e-04  4.097533e-04  4.270637e-04
## ASV2390      1.274896e-03  1.330934e-03  1.389216e-03  1.449811e-03
## ASV0548      1.119365e-03  1.170734e-03  1.224376e-03  1.280383e-03
## ASV0168     -7.544622e-04 -7.884042e-04 -8.237855e-04 -8.606596e-04
## ASV0066     -6.189764e-04 -6.473051e-04 -6.768771e-04 -7.077423e-04
## ASV0468     -3.998935e-04 -4.183737e-04 -4.376817e-04 -4.578525e-04
## ASV0172     -1.903302e-04 -1.980700e-04 -2.060629e-04 -2.143115e-04
## ASV0236     -3.559323e-04 -3.691249e-04 -3.826216e-04 -3.964109e-04
## ASV0250      4.060663e-04  4.278811e-04  4.509444e-04  4.753320e-04
## ASV0338      3.886047e-04  4.080272e-04  4.284458e-04  4.499126e-04
## ASV0450     -3.303704e-05 -3.495914e-05 -3.700463e-05 -3.918217e-05
## ASV0377      8.561855e-04  8.953928e-04  9.363223e-04  9.790430e-04
## ASV1022      1.107454e-04  1.159032e-04  1.212961e-04  1.269346e-04
## ASV6174     -1.005768e-04 -1.055577e-04 -1.107922e-04 -1.162936e-04
## ASV0786      7.849796e-05  8.126575e-05  8.407665e-05  8.692495e-05
## ASV0053     -7.901953e-04 -8.268171e-04 -8.650885e-04 -9.050792e-04
## ASV0697     -6.333280e-04 -6.616888e-04 -6.912419e-04 -7.220307e-04
## ASV0785      1.176381e-03  1.229697e-03  1.285315e-03  1.343325e-03
## ASV1967     -1.080284e-03 -1.128951e-03 -1.179684e-03 -1.232557e-03
## ASV0385      1.479404e-04  1.558583e-04  1.642196e-04  1.730495e-04
## ASV0295      4.284936e-05  4.563508e-05  4.862026e-05  5.182011e-05
## ASV0072     -7.613849e-04 -7.952768e-04 -8.305717e-04 -8.673187e-04
## ASV0157     -2.802651e-04 -2.920014e-04 -3.041492e-04 -3.167148e-04
## ASV0501      1.947081e-03  2.039391e-03  2.136014e-03  2.237140e-03
## ASV10729    -2.300937e-03 -2.408284e-03 -2.520531e-03 -2.637892e-03
## ASV1470      1.352180e-03  1.408219e-03  1.466213e-03  1.526201e-03
## ASV0050     -1.783479e-03 -1.864531e-03 -1.949093e-03 -2.037303e-03
## ASV0411     -3.235690e-04 -3.383398e-04 -3.537618e-04 -3.698619e-04
## ASV0549      5.704141e-04  5.971363e-04  6.250931e-04  6.543402e-04
## ASV0184      1.774187e-04  1.855025e-04  1.939380e-04  2.027391e-04
## ASV0705      4.599595e-04  4.812700e-04  5.035376e-04  5.268023e-04
## ASV1715      1.038956e-03  1.086806e-03  1.136785e-03  1.188981e-03
## ASV0603      1.639102e-04  1.717011e-04  1.798621e-04  1.884107e-04
## ASV0826      1.412162e-03  1.475937e-03  1.542436e-03  1.611760e-03
## ASV0034     -5.696589e-04 -5.952515e-04 -6.219227e-04 -6.497115e-04
## ASV0838      7.884131e-04  8.234018e-04  8.598155e-04  8.977000e-04
## ASV0614     -6.515817e-04 -6.814442e-04 -7.126216e-04 -7.451668e-04
## ASV0014     -1.021756e-03 -1.068437e-03 -1.117163e-03 -1.168016e-03
## ASV0585     -8.696387e-05 -9.118488e-05 -9.561929e-05 -1.002789e-04
## ASV0016     -1.071730e-03 -1.120710e-03 -1.171837e-03 -1.225196e-03
## ASV5394     -1.042165e-03 -1.090390e-03 -1.140780e-03 -1.193424e-03
## ASV0666      1.952277e-03  2.039746e-03  2.130879e-03  2.225809e-03
## ASV2085      4.425755e-04  4.590923e-04  4.759907e-04  4.932548e-04
## ASV0003     -7.437364e-04 -7.776839e-04 -8.131158e-04 -8.500911e-04
## ASV0346      1.841921e-04  1.937800e-04  2.038935e-04  2.145629e-04
## ASV0267     -9.816415e-05 -1.017489e-04 -1.054016e-04 -1.091159e-04
## ASV0353      6.041249e-04  6.335566e-04  6.644369e-04  6.968372e-04
## ASV2419      2.033860e-03  2.125830e-03  2.221736e-03  2.321727e-03
## ASV0447      8.472499e-04  8.873884e-04  9.294127e-04  9.734093e-04
## ASV0654      1.392732e-03  1.456982e-03  1.524099e-03  1.594202e-03
## ASV0151      1.150121e-04  1.210650e-04  1.274580e-04  1.342116e-04
## ASV0065     -5.653051e-04 -5.905975e-04 -6.169491e-04 -6.443980e-04
## ASV0527      1.505187e-03  1.574120e-03  1.646083e-03  1.721201e-03
## ASV4055     -3.488604e-04 -3.658837e-04 -3.837548e-04 -4.025171e-04
## ASV0166     -7.678294e-04 -8.006742e-04 -8.347628e-04 -8.701286e-04
## ASV0417     -5.742691e-04 -5.996021e-04 -6.259588e-04 -6.533721e-04
## ASV0078     -4.084755e-04 -4.264544e-04 -4.451586e-04 -4.646118e-04
## ASV0322     -4.875118e-04 -5.071861e-04 -5.275008e-04 -5.484637e-04
## ASV0156     -9.448556e-04 -9.872271e-04 -1.031391e-03 -1.077416e-03
## ASV0648     -2.895834e-03 -3.031073e-03 -3.172500e-03 -3.320387e-03
## ASV0407     -8.339927e-05 -8.749441e-05 -9.179123e-05 -9.629937e-05
## ASV2030     -3.905786e-04 -4.082473e-04 -4.266781e-04 -4.459010e-04
## ASV0300      2.467425e-04  2.588706e-04  2.716044e-04  2.849742e-04
## ASV1150     -2.233175e-05 -2.313423e-05 -2.395139e-05 -2.478193e-05
## ASV0958      7.310551e-04  7.659275e-04  8.024636e-04  8.407427e-04
## ASV0216     -8.369715e-04 -8.747294e-04 -9.140979e-04 -9.551380e-04
## ASV0446      1.242144e-03  1.300758e-03  1.362103e-03  1.426304e-03
## ASV0367     -9.327368e-04 -9.760167e-04 -1.021253e-03 -1.068530e-03
## ASV0200     -5.229574e-04 -5.468000e-04 -5.716840e-04 -5.976510e-04
## ASV0334     -3.201471e-04 -3.333413e-04 -3.469819e-04 -3.610751e-04
## ASV1311      3.463740e-04  3.617663e-04  3.777913e-04  3.944707e-04
## ASV0458      7.468738e-04  7.797276e-04  8.138983e-04  8.494270e-04
## ASV1371      7.895527e-05  8.273866e-05  8.670301e-05  9.085677e-05
## ASV0418      1.812510e-03  1.891677e-03  1.973987e-03  2.059537e-03
## ASV0004      1.759045e-04  1.837295e-04  1.918773e-04  2.003593e-04
## ASV1943      6.213860e-03  6.488013e-03  6.773302e-03  7.070097e-03
## ASV1495     -2.711089e-04 -2.858694e-04 -3.014954e-04 -3.180418e-04
## ASV0901     -1.157670e-03 -1.211862e-03 -1.268547e-03 -1.327837e-03
## ASV0628      5.373324e-04  5.610357e-04  5.856950e-04  6.113405e-04
## ASV0400      2.815347e-04  2.944138e-04  3.078550e-04  3.218803e-04
## ASV0116     -3.256495e-04 -3.407852e-04 -3.566081e-04 -3.731480e-04
## ASV0788      2.311996e-03  2.419537e-03  2.531959e-03  2.649473e-03
## ASV0117      2.028551e-04  2.126136e-04  2.228451e-04  2.335729e-04
## ASV3137     -6.842149e-06 -7.049931e-06 -7.255946e-06 -7.458979e-06
## ASV0001      2.120275e-04  2.213684e-04  2.310876e-04  2.411975e-04
## ASV1651      5.450341e-04  5.688617e-04  5.936357e-04  6.193856e-04
## ASV1692      1.929798e-03  2.020022e-03  2.114384e-03  2.213065e-03
## ASV0660      6.385786e-04  6.660799e-04  6.946214e-04  7.242287e-04
## ASV0508     -1.156282e-05 -1.242044e-05 -1.334522e-05 -1.434245e-05
## ASV1660     -5.577387e-04 -5.845962e-04 -6.127542e-04 -6.422758e-04
## ASV0233      4.109173e-04  4.297521e-04  4.494181e-04  4.699490e-04
## ASV1343     -1.302284e-03 -1.363133e-03 -1.426772e-03 -1.493324e-03
## ASV0209      5.985269e-04  6.251409e-04  6.528516e-04  6.816966e-04
## ASV0193     -8.069010e-04 -8.409642e-04 -8.762774e-04 -9.128707e-04
## ASV0357      1.509988e-04  1.585370e-04  1.664652e-04  1.748045e-04
## ASV0198      4.803189e-04  5.026658e-04  5.260239e-04  5.504357e-04
## ASV0007      2.219640e-04  2.316918e-04  2.418090e-04  2.523279e-04
## ASV1772     -3.235774e-04 -3.379004e-04 -3.528034e-04 -3.683044e-04
## ASV0009      2.074695e-04  2.165187e-04  2.259263e-04  2.357031e-04
## ASV0006     -2.522179e-05 -2.668968e-05 -2.824942e-05 -2.990701e-05
## ASV0011     -4.101710e-04 -4.292688e-04 -4.492346e-04 -4.701059e-04
## ASV0015      1.351305e-04  1.410482e-04  1.472009e-04  1.535959e-04
## ASV0017      1.467805e-04  1.532060e-04  1.598868e-04  1.668307e-04
## ASV0235     -5.103710e-04 -5.346394e-04 -5.600534e-04 -5.866658e-04
## ASV0382      2.121815e-04  2.227639e-04  2.338848e-04  2.455719e-04
## ASV2357      1.645277e-03  1.721807e-03  1.801813e-03  1.885446e-03
## ASV0567     -4.357230e-04 -4.555944e-04 -4.763359e-04 -4.979825e-04
## ASV0165      2.883440e-04  3.018747e-04  3.160298e-04  3.308369e-04
## ASV0005      3.504558e-04  3.662998e-04  3.828224e-04  4.000495e-04
## ASV0384     -2.125896e-05 -2.155053e-05 -2.179020e-05 -2.196972e-05
## ASV0002      6.004897e-05  6.278551e-05  6.564115e-05  6.862056e-05
## ASV3017      2.256382e-03  2.357657e-03  2.463200e-03  2.573169e-03
## ASV0091     -6.761119e-07 -6.616652e-07 -6.428844e-07 -6.193303e-07
## ASV0186     -9.170452e-04 -9.593085e-04 -1.003453e-03 -1.049556e-03
## ASV0370      2.700005e-04  2.827303e-04  2.960545e-04  3.100004e-04
## ASV0018      4.782769e-04  4.999486e-04  5.225533e-04  5.461269e-04
## ASV1377      7.255512e-03  7.583114e-03  7.924683e-03  8.280742e-03
## ASV0019      5.009349e-04  5.236483e-04  5.473409e-04  5.720506e-04
## ASV0023     -1.488573e-04 -1.560637e-04 -1.636209e-04 -1.715459e-04
## ASV2194      5.629721e-04  5.885529e-04  6.152498e-04  6.431083e-04
## ASV1155      1.082779e-03  1.132873e-03  1.185210e-03  1.239884e-03
## ASV0510     -8.228849e-04 -8.566203e-04 -8.915047e-04 -9.275581e-04
## ASV2371     -1.218816e-03 -1.272650e-03 -1.328668e-03 -1.386942e-03
## ASV0024     -2.012036e-04 -2.108321e-04 -2.209202e-04 -2.314895e-04
## ASV2452      1.406485e-03  1.468440e-03  1.532901e-03  1.599947e-03
## ASV2332     -1.624879e-03 -1.698879e-03 -1.776043e-03 -1.856487e-03
## ASV2591      1.093618e-03  1.148008e-03  1.205181e-03  1.265285e-03
## ASV0521      7.691986e-04  8.052439e-04  8.429474e-04  8.823822e-04
## ASV5542      6.723424e-04  7.038829e-04  7.368749e-04  7.713821e-04
## ASV0336     -2.469810e-04 -2.574183e-04 -2.682477e-04 -2.794807e-04
## ASV10102     1.412345e-03  1.478704e-03  1.548135e-03  1.620777e-03
## ASV16823    -2.033609e-03 -2.123191e-03 -2.216389e-03 -2.313319e-03
## ASV3104      1.122147e-02  1.171573e-02  1.222993e-02  1.276472e-02
## ASV0781      1.292005e-03  1.351877e-03  1.414446e-03  1.479827e-03
## ASV10899     8.090901e-04  8.493827e-04  8.917446e-04  9.362859e-04
## ASV11222    -3.551518e-03 -3.707939e-03 -3.870670e-03 -4.039915e-03
## ASV11327    -3.194045e-03 -3.334705e-03 -3.481039e-03 -3.633228e-03
## ASV12458    -3.550732e-03 -3.707083e-03 -3.869737e-03 -4.038899e-03
## ASV1636      2.845870e-04  2.982509e-04  3.125724e-04  3.275827e-04
## ASV1890     -2.299825e-03 -2.400215e-03 -2.504570e-03 -2.613010e-03
## ASV2898      2.720870e-03  2.843896e-03  2.972183e-03  3.105928e-03
## ASV8328      1.040275e-04  1.140971e-04  1.250984e-04  1.371134e-04
## ASV0709     -3.019301e-03 -3.156676e-03 -3.300006e-03 -3.449524e-03
## ASV0856      2.105043e-03  2.204733e-03  2.309109e-03  2.418387e-03
## ASV0909     -1.640969e-04 -1.666255e-04 -1.688111e-04 -1.705994e-04
## ASV0937     -1.756065e-03 -1.837254e-03 -1.922089e-03 -2.010722e-03
## ASV11390    -5.029032e-03 -5.250446e-03 -5.480784e-03 -5.720335e-03
## ASV11966     1.198375e-03  1.256167e-03  1.316768e-03  1.380313e-03
## ASV12990     8.019433e-04  8.389890e-04  8.776905e-04  9.181163e-04
## ASV14797     1.365147e-03  1.426511e-03  1.490467e-03  1.557109e-03
## ASV14904    -7.138690e-03 -7.452979e-03 -7.779936e-03 -8.119970e-03
## ASV15304     6.355973e-04  6.675943e-04  7.012624e-04  7.366925e-04
## ASV16696    -2.525011e-03 -2.636168e-03 -2.751805e-03 -2.872066e-03
## ASV1690      4.272585e-03  4.474626e-03  4.686115e-03  4.907479e-03
## ASV2029      3.074061e-03  3.213461e-03  3.358861e-03  3.510490e-03
## ASV2834      4.949739e-03  5.178532e-03  5.417572e-03  5.667290e-03
## ASV4003      2.972245e-03  3.115437e-03  3.265586e-03  3.423031e-03
## ASV4064      1.861464e-03  1.946791e-03  2.035875e-03  2.128869e-03
## ASV4294      1.048662e-03  1.101036e-03  1.156120e-03  1.214061e-03
## ASV4609      5.723015e-04  5.975673e-04  6.238683e-04  6.512409e-04
## ASV6283     -2.362398e-03 -2.466404e-03 -2.574603e-03 -2.687130e-03
## ASV6491     -3.368527e-03 -3.516812e-03 -3.671073e-03 -3.831502e-03
## ASV7453      1.519275e-03  1.592820e-03  1.669956e-03  1.750858e-03
## ASV7959      3.929906e-04  4.143197e-04  4.368913e-04  4.607827e-04
## ASV8219      3.471836e-02  3.624661e-02  3.783643e-02  3.948983e-02
## ASV8547     -3.020635e-03 -3.153583e-03 -3.291887e-03 -3.435719e-03
## ASV9319      1.306781e-03  1.368343e-03  1.432771e-03  1.500193e-03
## ASV9382     -5.826151e-03 -6.082563e-03 -6.349304e-03 -6.626705e-03
## ASV11516    -3.928789e-03 -4.101677e-03 -4.281528e-03 -4.468565e-03
## ASV14377    -2.851981e-03 -2.977469e-03 -3.108010e-03 -3.243765e-03
## ASV1867      2.399909e-03  2.511720e-03  2.628626e-03  2.750848e-03
## ASV1895      4.096002e-04  4.282769e-04  4.477542e-04  4.680606e-04
## ASV3168      1.319381e-03  1.378533e-03  1.440165e-03  1.504365e-03
## ASV4449      8.469140e-03  8.855726e-03  9.259206e-03  9.680252e-03
## ASV6596      1.614054e-03  1.692752e-03  1.775359e-03  1.862073e-03
## ASV7492     -3.845786e-04 -3.984879e-04 -4.126723e-04 -4.271128e-04
## ASV9854     -7.426027e-04 -7.746331e-04 -8.078934e-04 -8.424172e-04
## ASV6296      6.400109e-02  6.681674e-02  6.974572e-02  7.279166e-02
## ASV4201      6.913091e-04  7.278029e-04  7.663469e-04  8.070644e-04
## ASV0552      1.560151e-03  1.632948e-03  1.709067e-03  1.788653e-03
## ASV3671     -7.997311e-04 -8.349233e-04 -8.715401e-04 -9.096290e-04
## ASV3529     -4.001273e-04 -4.154363e-04 -4.311481e-04 -4.472554e-04
## ASV1060      6.011514e-04  6.292672e-04  6.586744e-04  6.894300e-04
## ASV0239     -6.330676e-04 -6.604591e-04 -6.889037e-04 -7.184296e-04
## ASV5711     -2.479475e-03 -2.591112e-03 -2.707486e-03 -2.828773e-03
## ASV4152     -4.034277e-03 -4.218019e-03 -4.409745e-03 -4.609769e-03
## ASV1461      1.860291e-03  1.942561e-03  2.028177e-03  2.117249e-03
## ASV2877      9.622189e-04  1.004700e-03  1.048902e-03  1.094879e-03
## ASV0012      1.328705e-04  1.390059e-04  1.454156e-04  1.521109e-04
## ASV9823      3.054144e-04  3.162381e-04  3.272792e-04  3.385271e-04
## ASV0008      1.420825e-04  1.486030e-04  1.554114e-04  1.625194e-04
## ASV7832     -2.523275e-03 -2.639119e-03 -2.760085e-03 -2.886383e-03
## ASV1915     -5.397462e-05 -5.547958e-05 -5.696682e-05 -5.842880e-05
## ASV0055      1.456763e-05  1.474695e-05  1.488775e-05  1.498402e-05
## ASV0032      2.677813e-04  2.797808e-04  2.922841e-04  3.053092e-04
## ASV2977     -3.526704e-03 -3.686124e-03 -3.852356e-03 -4.025655e-03
## ASV0466      2.628883e-03  2.744027e-03  2.863751e-03  2.988193e-03
## ASV3866      1.794991e-03  1.878639e-03  1.966099e-03  2.057536e-03
## ASV0040      4.758228e-04  4.978387e-04  5.208429e-04  5.448771e-04
## ASV0496     -1.737056e-04 -1.837797e-04 -1.944931e-04 -2.058894e-04
## ASV0052      6.072225e-04  6.350392e-04  6.640796e-04  6.943931e-04
## ASV3828     -3.736741e-03 -3.906890e-03 -4.084441e-03 -4.269688e-03
## ASV1930      1.174788e-03  1.228668e-03  1.284919e-03  1.343638e-03
## ASV2126      1.448200e-03  1.513982e-03  1.582607e-03  1.654186e-03
## ASV0793      1.646514e-03  1.722952e-03  1.802841e-03  1.886329e-03
## ASV0299     -1.314110e-04 -1.374306e-04 -1.437159e-04 -1.502780e-04
## ASV0208      1.178137e-03  1.233399e-03  1.291207e-03  1.351675e-03
## ASV0511     -6.748882e-04 -7.046112e-04 -7.355346e-04 -7.676974e-04
## ASV1123     -2.144327e-03 -2.237831e-03 -2.335020e-03 -2.436004e-03
## ASV0099     -6.642978e-05 -6.890853e-05 -7.144532e-05 -7.403795e-05
## ASV0752     -6.590826e-04 -6.909586e-04 -7.243943e-04 -7.594672e-04
## ASV0883      8.354404e-04  8.747559e-04  9.158952e-04  9.589401e-04
## ASV0683      1.742815e-03  1.824916e-03  1.910837e-03  2.000750e-03
## ASV4117     -4.278097e-03 -4.472608e-03 -4.675546e-03 -4.887238e-03
## ASV2172      3.455313e-04  3.607929e-04  3.766755e-04  3.931995e-04
## ASV0330     -4.967861e-04 -5.195507e-04 -5.433215e-04 -5.681398e-04
## ASV0728      2.619042e-03  2.739439e-03  2.865168e-03  2.996448e-03
## ASV0499      6.359333e-04  6.659010e-04  6.972655e-04  7.300904e-04
## ASV0120     -1.090856e-03 -1.140839e-03 -1.193020e-03 -1.247487e-03
## ASV1446      1.067773e-03  1.113055e-03  1.159989e-03  1.208611e-03
## ASV17171    -1.946940e-03 -2.036193e-03 -2.129383e-03 -2.226672e-03
## ASV0533      1.808979e-04  1.896395e-04  1.988079e-04  2.084240e-04
## ASV2495     -7.040326e-04 -7.383840e-04 -7.744468e-04 -8.123092e-04
## ASV5582      8.617462e-04  8.973895e-04  9.342529e-04  9.723547e-04
## ASV1488      7.436681e-04  7.810671e-04  8.203788e-04  8.616993e-04
## ASV0682      4.743794e-04  4.969959e-04  5.206903e-04  5.455139e-04
## ASV0068     -5.159014e-04 -5.397649e-04 -5.646970e-04 -5.907421e-04
## ASV1987     -1.928854e-03 -2.020798e-03 -2.117119e-03 -2.218027e-03
## ASV0035     -7.768366e-05 -8.229271e-05 -8.720386e-05 -9.243872e-05
## ASV7192     -1.453710e-03 -1.518595e-03 -1.586175e-03 -1.656546e-03
## ASV0873      5.883664e-04  5.999570e-04  6.106765e-04  6.203695e-04
## ASV4749     -7.060963e-07 -4.272997e-06 -8.326306e-06 -1.291617e-05
## ASV2174      1.387941e-03  1.446356e-03  1.506914e-03  1.569666e-03
## ASV1476     -8.985438e-04 -9.403147e-04 -9.839838e-04 -1.029634e-03
## ASV0740     -3.100518e-03 -3.245602e-03 -3.397350e-03 -3.556055e-03
## ASV0170     -4.003013e-04 -4.187939e-04 -4.381138e-04 -4.582958e-04
## ASV2466     -3.000203e-03 -3.138167e-03 -3.282255e-03 -3.432720e-03
## ASV1709      1.250706e-03  1.306301e-03  1.364191e-03  1.424456e-03
## ASV6170     -7.059686e-03 -7.376269e-03 -7.706305e-03 -8.050314e-03
## ASV3673      2.111745e-03  2.205175e-03  2.302472e-03  2.403777e-03
## ASV1745      3.281263e-04  3.391150e-04  3.502672e-04  3.615670e-04
## ASV0380     -1.687822e-03 -1.752350e-03 -1.818670e-03 -1.886775e-03
## ASV0426      9.786568e-05  1.047953e-04  1.122367e-04  1.202271e-04
## ASV0202      1.192899e-05  1.403199e-05  1.636978e-05  1.896461e-05
## ASV6350     -2.324062e-03 -2.424106e-03 -2.528068e-03 -2.636073e-03
## ASV0713     -9.806281e-04 -1.026137e-03 -1.073704e-03 -1.123418e-03
## ASV1822      8.102002e-05  8.610777e-05  9.152933e-05  9.730615e-05
## ASV4569      2.980787e-03  3.113092e-03  3.250890e-03  3.394382e-03
## ASV0030     -2.670327e-04 -2.795935e-04 -2.927333e-04 -3.064774e-04
## ASV0331      1.059631e-03  1.109844e-03  1.162419e-03  1.217463e-03
## ASV2981      3.026523e-03  3.168066e-03  3.316079e-03  3.470839e-03
## ASV0828     -4.841092e-04 -5.184685e-04 -5.553949e-04 -5.950801e-04
## ASV2440      2.638934e-03  2.762057e-03  2.890794e-03  3.025388e-03
## ASV3006     -1.406492e-02 -1.462744e-02 -1.520829e-02 -1.580777e-02
## ASV3875      1.307649e-01  1.359942e-01  1.413940e-01  1.469669e-01
## ASV4511      1.487091e-03  1.557041e-03  1.630240e-03  1.706837e-03
## ASV4700     -5.171347e-03 -5.378128e-03 -5.591648e-03 -5.812013e-03
## ASV5804     -1.214365e-01 -1.262918e-01 -1.313052e-01 -1.364794e-01
## ASV6826      2.138794e-03  2.240276e-03  2.346549e-03  2.457836e-03
## ASV7280      1.992879e-03  2.089049e-03  2.189852e-03  2.295503e-03
## ASV7535     -5.170561e-03 -5.377283e-03 -5.590739e-03 -5.811038e-03
## ASV0651     -1.060744e-03 -1.107669e-03 -1.156496e-03 -1.207287e-03
## ASV0913      2.425414e-03  2.539440e-03  2.658762e-03  2.783619e-03
## ASV10832    -5.516985e-03 -5.737536e-03 -5.965270e-03 -6.200303e-03
## ASV1117     -5.499984e-03 -5.744019e-03 -5.998165e-03 -6.262784e-03
## ASV11329     8.546516e-04  8.994053e-04  9.466130e-04  9.964142e-04
## ASV13209     1.462940e-04  1.599905e-04  1.748344e-04  1.909093e-04
## ASV1345      1.299095e-03  1.361806e-03  1.427498e-03  1.496302e-03
## ASV1719     -7.768737e-03 -8.079274e-03 -8.399924e-03 -8.730850e-03
## ASV1886      1.473467e-03  1.539639e-03  1.608638e-03  1.680572e-03
## ASV2158     -6.501677e-05 -6.030436e-05 -5.480076e-05 -4.843644e-05
## ASV2189      2.484997e-03  2.598599e-03  2.717196e-03  2.840991e-03
## ASV2257      2.574766e-03  2.691239e-03  2.812769e-03  2.939561e-03
## ASV2283      6.017643e-03  6.258128e-03  6.506439e-03  6.762701e-03
## ASV2328      3.707153e-03  3.855288e-03  4.008242e-03  4.166094e-03
## ASV2434     -3.547845e-03 -3.702426e-03 -3.863225e-03 -4.030458e-03
## ASV2648      6.766290e-03  7.036598e-03  7.315696e-03  7.603723e-03
## ASV2698      6.785505e-03  7.100202e-03  7.429165e-03  7.773013e-03
## ASV2775      2.102432e-03  2.193742e-03  2.288651e-03  2.387270e-03
## ASV3171      3.261380e-03  3.391638e-03  3.526130e-03  3.664921e-03
## ASV3227      3.237964e-03  3.377438e-03  3.522301e-03  3.672708e-03
## ASV3397      1.550151e-03  1.624266e-03  1.701844e-03  1.783034e-03
## ASV3444      4.642476e-03  4.842682e-03  5.050766e-03  5.266987e-03
## ASV3556      1.356409e-02  1.410569e-02  1.466488e-02  1.524193e-02
## ASV3606     -3.188028e-02 -3.315310e-02 -3.446724e-02 -3.582336e-02
## ASV4190      4.351442e-03  4.551411e-03  4.760281e-03  4.978425e-03
## ASV4197      2.743673e-03  2.861709e-03  2.984319e-03  3.111641e-03
## ASV4722      4.165268e-03  4.352811e-03  4.548354e-03  4.752202e-03
## ASV4765      2.203537e-03  2.307208e-03  2.415580e-03  2.528841e-03
## ASV4809      8.013983e-03  8.333859e-03  8.664114e-03  9.004910e-03
## ASV4846      3.769630e-03  3.944043e-03  4.126260e-03  4.316600e-03
## ASV4903     -1.713414e-04 -1.710682e-04 -1.701529e-04 -1.685271e-04
## ASV4944     -3.282152e-03 -3.413150e-03 -3.548398e-03 -3.687962e-03
## ASV5151      4.085731e-04  3.871686e-04  3.615562e-04  3.313217e-04
## ASV5413     -7.219907e-03 -7.508050e-03 -7.805539e-03 -8.112522e-03
## ASV5537     -7.756214e-03 -8.065729e-03 -8.385282e-03 -8.715031e-03
## ASV5688      6.519102e-03  6.779224e-03  7.047780e-03  7.324902e-03
## ASV5752      1.939498e-03  2.032437e-03  2.129746e-03  2.231615e-03
## ASV6122     -8.350736e-03 -8.683923e-03 -9.027912e-03 -9.382872e-03
## ASV6135      4.383805e-03  4.558697e-03  4.739259e-03  4.925577e-03
## ASV6188     -2.661594e-02 -2.767768e-02 -2.877383e-02 -2.990492e-02
## ASV6216      6.051533e-03  6.315756e-03  6.590576e-03  6.876348e-03
## ASV6242      4.382544e-03  4.557333e-03  4.737783e-03  4.923982e-03
## ASV6383      2.740153e-02  2.849427e-02  2.962240e-02  3.078646e-02
## ASV6781      6.098046e-03  6.341206e-03  6.592237e-03  6.851262e-03
## ASV6799     -1.157984e-02 -1.204154e-02 -1.251819e-02 -1.301000e-02
## ASV7374     -2.457132e-03 -2.555091e-03 -2.656219e-03 -2.760566e-03
## ASV7539     -3.278073e-03 -3.408747e-03 -3.543649e-03 -3.682843e-03
## ASV8591     -8.342551e-03 -8.675079e-03 -9.018360e-03 -9.372563e-03
## ASV8637      3.662292e-02  3.808254e-02  3.958935e-02  4.114409e-02
## ASV12796    -4.832855e-03 -5.025450e-03 -5.224272e-03 -5.429415e-03
## ASV1934      2.519442e-03  2.635920e-03  2.757630e-03  2.884793e-03
## ASV22549     2.403178e-04  2.567932e-04  2.744243e-04  2.932879e-04
## ASV29857    -1.874536e-03 -1.949233e-03 -2.026345e-03 -2.105909e-03
## ASV3215      2.679767e-03  2.806136e-03  2.938414e-03  3.076876e-03
## ASV3236     -4.831902e-03 -5.024424e-03 -5.223167e-03 -5.428227e-03
## ASV3954     -4.831424e-03 -5.023908e-03 -5.222610e-03 -5.427626e-03
## ASV4850      3.238630e-03  3.367644e-03  3.500825e-03  3.638238e-03
## ASV5225      3.127287e-02  3.251853e-02  3.380442e-02  3.513115e-02
## ASV5532     -1.670314e-03 -1.736839e-03 -1.805513e-03 -1.876366e-03
## ASV7258      1.355353e-03  1.428336e-03  1.505463e-03  1.586977e-03
## ASV9474     -4.972636e-04 -5.106152e-04 -5.238078e-04 -5.367822e-04
## ASV11857    -6.275817e-03 -6.525761e-03 -6.783774e-03 -7.049982e-03
## ASV1202     -3.985291e-03 -4.143996e-03 -4.307823e-03 -4.476851e-03
## ASV14742     1.117024e-03  1.173856e-03  1.233679e-03  1.296653e-03
## ASV16652     8.581450e-04  8.999483e-04  9.437557e-04  9.896552e-04
## ASV2019      2.971420e-03  3.101728e-03  3.237310e-03  3.378346e-03
## ASV2410     -6.609537e-03 -6.911968e-03 -7.227796e-03 -7.557585e-03
## ASV2718      1.640106e-03  1.717929e-03  1.799401e-03  1.884686e-03
## ASV2738      4.873871e-03  5.086529e-03  5.307655e-03  5.537521e-03
## ASV2876      2.897537e-03  3.012899e-03  3.131984e-03  3.254848e-03
## ASV3177      3.882593e-03  4.037159e-03  4.196711e-03  4.361325e-03
## ASV4367      4.797467e-03  4.988436e-03  5.185564e-03  5.388943e-03
## ASV4635      1.525741e-03  1.603673e-03  1.685663e-03  1.771919e-03
## ASV4896      1.126047e-03  1.189207e-03  1.256129e-03  1.327046e-03
## ASV4907      1.290497e-03  1.355210e-03  1.423244e-03  1.494771e-03
## ASV5230     -3.734759e-03 -3.883445e-03 -4.036927e-03 -4.195281e-03
## ASV6509     -3.983460e-03 -4.142031e-03 -4.305716e-03 -4.474595e-03
## ASV7376     -2.849843e-03 -2.963276e-03 -3.080368e-03 -3.201173e-03
## ASV8163     -4.246340e-03 -4.415342e-03 -4.589792e-03 -4.769775e-03
## ASV8195     -3.733283e-03 -3.881851e-03 -4.035207e-03 -4.193426e-03
## ASV8923      1.184513e-03  1.243314e-03  1.305067e-03  1.369918e-03
## ASV9666     -1.972006e-03 -2.039969e-03 -2.109145e-03 -2.179456e-03
## ASV1482      1.995842e-03  2.090275e-03  2.189118e-03  2.292570e-03
## ASV2726      1.835438e-03  1.922613e-03  2.013880e-03  2.109424e-03
## ASV3281     -1.555477e-02 -1.617377e-02 -1.681272e-02 -1.747193e-02
## ASV4235     -1.555324e-02 -1.617211e-02 -1.681093e-02 -1.747000e-02
## ASV4808      3.210147e-03  3.350638e-03  3.496819e-03  3.648888e-03
## ASV4861     -7.856330e-03 -8.197490e-03 -8.552288e-03 -8.921194e-03
## ASV5276      4.580114e-03  4.780221e-03  4.988373e-03  5.204843e-03
## ASV5837      1.486903e-03  1.556422e-03  1.629147e-03  1.705224e-03
## ASV7098      2.137540e-03  2.236724e-03  2.340415e-03  2.448809e-03
## ASV8451     -2.646744e-03 -2.752002e-03 -2.860647e-03 -2.972731e-03
## ASV8694     -1.554449e-02 -1.616261e-02 -1.680062e-02 -1.745882e-02
## ASV0905     -6.883815e-04 -7.214013e-04 -7.559508e-04 -7.920911e-04
## ASV2900      3.608153e-03  3.759672e-03  3.916794e-03  4.079673e-03
## ASV3963     -3.665675e-03 -3.816897e-03 -3.973489e-03 -4.135583e-03
## ASV0041     -6.436918e-04 -6.740629e-04 -7.058451e-04 -7.391013e-04
## ASV1865      1.900536e-03  1.992615e-03  2.089163e-03  2.190393e-03
## ASV1140      1.068491e-03  1.119411e-03  1.172713e-03  1.228499e-03
## ASV1179      1.106961e-03  1.158093e-03  1.211508e-03  1.267300e-03
## ASV0279      1.686534e-03  1.762745e-03  1.842237e-03  1.925137e-03
## ASV0043     -2.947003e-04 -3.095360e-04 -3.251502e-04 -3.415864e-04
## ASV2097     -1.008593e-03 -1.052265e-03 -1.097678e-03 -1.144892e-03
## ASV0309     -1.993492e-04 -2.081772e-04 -2.173694e-04 -2.269386e-04
## ASV0607      2.634632e-03  2.757062e-03  2.885038e-03  3.018798e-03
## ASV0025     -7.324967e-04 -7.667655e-04 -8.026025e-04 -8.400757e-04
## ASV2284     -2.871194e-03 -2.992895e-03 -3.119175e-03 -3.250167e-03
## ASV0556      7.419028e-04  7.781729e-04  8.162333e-04  8.561720e-04
## ASV5040     -2.565871e-03 -2.728610e-03 -2.902201e-03 -3.087360e-03
## ASV2924     -9.214005e-03 -9.596032e-03 -9.991736e-03 -1.040145e-02
## ASV1331      2.337216e-03  2.444383e-03  2.556288e-03  2.673124e-03
## ASV0506     -1.023357e-03 -1.065754e-03 -1.109633e-03 -1.155022e-03
## ASV1514      3.540675e-03  3.703135e-03  3.872758e-03  4.049830e-03
## ASV2144      3.377965e-03  3.532556e-03  3.693952e-03  3.862431e-03
## ASV2265      2.221598e-03  2.323711e-03  2.430350e-03  2.541700e-03
## ASV5156      1.717267e-03  1.784742e-03  1.854269e-03  1.925861e-03
## ASV5534      5.234420e-04  5.423950e-04  5.617626e-04  5.815288e-04
## ASV5747     -5.636419e-04 -6.136285e-04 -6.678206e-04 -7.265423e-04
## ASV6657      1.731055e-03  1.806749e-03  1.885472e-03  1.967323e-03
## ASV0658     -1.290356e-03 -1.344707e-03 -1.401047e-03 -1.459424e-03
## ASV0716      2.311741e-03  2.414092e-03  2.520624e-03  2.631479e-03
## ASV1657      4.476904e-03  4.667517e-03  4.865291e-03  5.070415e-03
## ASV1885      3.790989e-03  3.942972e-03  4.099827e-03  4.261608e-03
## ASV2333      2.004578e-03  2.095030e-03  2.189345e-03  2.287669e-03
## ASV3375      1.564375e-03  1.631719e-03  1.701676e-03  1.774326e-03
## ASV4317      1.394018e-03  1.458525e-03  1.525954e-03  1.596432e-03
## ASV9599     -2.366963e-04 -2.576849e-04 -2.804390e-04 -3.050946e-04
## ASV0175     -2.177540e-03 -2.274731e-03 -2.375961e-03 -2.481370e-03
## ASV1032      9.235898e-04  9.627812e-04  1.003436e-03  1.045592e-03
## ASV1235      1.666746e-03  1.732500e-03  1.800240e-03  1.869974e-03
## ASV1262      2.240385e-03  2.341744e-03  2.447453e-03  2.557676e-03
## ASV1320      1.300557e-03  1.364742e-03  1.432156e-03  1.502965e-03
## ASV13797     1.298316e-03  1.355932e-03  1.415937e-03  1.478418e-03
## ASV1491      1.892559e-03  1.987348e-03  2.086959e-03  2.191637e-03
## ASV15014    -1.840675e-04 -2.003852e-04 -2.180749e-04 -2.372422e-04
## ASV1510      2.594645e-03  2.718635e-03  2.848494e-03  2.984489e-03
## ASV1551      8.784574e-03  9.189822e-03  9.613158e-03  1.005533e-02
## ASV1919      9.941498e-04  1.056853e-03  1.123732e-03  1.195063e-03
## ASV2114      1.615976e-03  1.686004e-03  1.758803e-03  1.834465e-03
## ASV21486    -1.580682e-04 -1.720765e-04 -1.872621e-04 -2.037156e-04
## ASV2448      1.669739e-03  1.743710e-03  1.820725e-03  1.900890e-03
## ASV2589      3.149047e-03  3.283637e-03  3.423353e-03  3.568342e-03
## ASV2608      2.115616e-03  2.210265e-03  2.308896e-03  2.411657e-03
## ASV2786      4.242475e-03  4.436257e-03  4.638599e-03  4.849860e-03
## ASV2827      1.497227e-03  1.563676e-03  1.632862e-03  1.704881e-03
## ASV2872      6.494563e-03  6.776983e-03  7.070500e-03  7.375448e-03
## ASV3125      1.268486e-03  1.323355e-03  1.380367e-03  1.439589e-03
## ASV3247      2.783617e-03  2.905186e-03  3.031599e-03  3.163011e-03
## ASV3451     -4.898114e-04 -5.332183e-04 -5.802731e-04 -6.312562e-04
## ASV3465      4.995029e-05  4.590568e-05  4.114944e-05  3.561063e-05
## ASV3809      3.747671e-03  3.910090e-03  4.078874e-03  4.254216e-03
## ASV4006      1.827501e-03  1.907535e-03  1.990772e-03  2.077314e-03
## ASV4046      2.685153e-03  2.802583e-03  2.924715e-03  3.051703e-03
## ASV4938      1.744637e-04  1.715581e-04  1.676232e-04  1.625483e-04
## ASV5435     -8.311392e-04 -9.047736e-04 -9.845934e-04 -1.071074e-03
## ASV5605      1.524175e-03  1.583972e-03  1.645552e-03  1.708917e-03
## ASV5635     -2.772366e-04 -3.017944e-04 -3.284145e-04 -3.572554e-04
## ASV5743      1.281206e-03  1.338011e-03  1.397161e-03  1.458740e-03
## ASV6627     -2.877379e-04 -3.132235e-04 -3.408492e-04 -3.707792e-04
## ASV6785     -3.203009e-04 -3.486676e-04 -3.794157e-04 -4.127281e-04
## ASV7368      1.596049e-03  1.669438e-03  1.746097e-03  1.826163e-03
## ASV9118      5.636537e-04  5.858641e-04  6.087590e-04  6.323444e-04
## ASV9135      1.039524e-03  1.078446e-03  1.118356e-03  1.159238e-03
## ASV9435      1.271861e-03  1.323460e-03  1.376759e-03  1.431781e-03
## ASV9671     -4.107667e-04 -4.471380e-04 -4.865619e-04 -5.292726e-04
## ASV0387     -2.247654e-03 -2.343788e-03 -2.443566e-03 -2.547088e-03
## ASV0454     -3.618836e-03 -3.776627e-03 -3.940668e-03 -4.111151e-03
## ASV0751     -1.027493e-03 -1.069700e-03 -1.113352e-03 -1.158473e-03
## ASV1081      2.207078e-03  2.307643e-03  2.412568e-03  2.522019e-03
## ASV1332      3.913492e-03  4.087951e-03  4.269646e-03  4.458828e-03
## ASV2659      4.351492e-03  4.550922e-03  4.759091e-03  4.976341e-03
## ASV2979      1.918255e-03  2.001072e-03  2.087091e-03  2.176405e-03
## ASV4184      2.726750e-03  2.837891e-03  2.952752e-03  3.071388e-03
## ASV6198      8.833215e-04  9.214425e-04  9.610647e-04  1.002238e-03
## ASV7454      9.422396e-04  9.827221e-04  1.024753e-03  1.068375e-03
## ASV8198      7.865344e-04  8.149010e-04  8.438701e-04  8.734153e-04
## ASV0855      2.374788e-03  2.483235e-03  2.596429e-03  2.714557e-03
## ASV10092     1.075246e-03  1.121773e-03  1.170124e-03  1.220357e-03
## ASV1532      2.128562e-03  2.228835e-03  2.333776e-03  2.443596e-03
## ASV2553      3.785753e-03  3.958991e-03  4.139843e-03  4.328618e-03
## ASV2741      5.210667e-03  5.457162e-03  5.715166e-03  5.985198e-03
## ASV4095      3.133170e-03  3.286584e-03  3.447535e-03  3.616380e-03
## ASV5295      1.081266e-03  1.125885e-03  1.172050e-03  1.219790e-03
## ASV5787     -1.689237e-04 -1.838748e-04 -2.000800e-04 -2.176353e-04
## ASV9455      1.457785e-03  1.521938e-03  1.588707e-03  1.658182e-03
## ASV10879     1.336041e-03  1.395964e-03  1.458431e-03  1.523541e-03
## ASV3997      1.749063e-03  1.833332e-03  1.921635e-03  2.014160e-03
## ASV6760      4.675671e-04  4.806098e-04  4.935267e-04  5.062585e-04
## ASV6990      1.366664e-03  1.425514e-03  1.486650e-03  1.550143e-03
## ASV9560      8.659355e-04  9.016744e-04  9.386704e-04  9.769516e-04
## ASV0220     -2.066307e-04 -2.159736e-04 -2.257177e-04 -2.358783e-04
## ASV2518      8.629159e-04  9.024683e-04  9.437633e-04  9.868717e-04
## ASV3615      2.171538e-03  2.268985e-03  2.370551e-03  2.476388e-03
## ASV0075     -7.744853e-06 -8.276903e-06 -8.846122e-06 -9.454949e-06
## ASV8070      9.376963e-05  9.489836e-05  9.581235e-05  9.648235e-05
## ASV1658      8.585530e-04  8.956838e-04  9.342664e-04  9.743454e-04
## ASV0773      1.584194e-03  1.653848e-03  1.726321e-03  1.801708e-03
## ASV0799      1.750164e-04  1.817264e-04  1.886103e-04  1.956641e-04
## ASV1839     -1.097442e-03 -1.146354e-03 -1.197289e-03 -1.250314e-03
## ASV0265      1.293268e-03  1.354760e-03  1.419155e-03  1.486588e-03
## ASV3741      4.589646e-04  4.782532e-04  4.982274e-04  5.188996e-04
## ASV0847      1.768375e-03  1.849576e-03  1.934368e-03  2.022898e-03
## ASV1026      2.315816e-03  2.420467e-03  2.529590e-03  2.643351e-03
## ASV1222     -6.057318e-04 -6.284695e-04 -6.517986e-04 -6.757121e-04
## ASV0729     -3.751811e-05 -3.928725e-05 -4.113930e-05 -4.307814e-05
## ASV0143     -5.816850e-04 -6.070762e-04 -6.334788e-04 -6.609250e-04
## ASV1328      2.921800e-04  3.074529e-04  3.235661e-04  3.405676e-04
## ASV9078     -6.633563e-04 -6.999598e-04 -7.386997e-04 -7.797042e-04
## ASV0027     -6.903938e-04 -7.226214e-04 -7.563169e-04 -7.915433e-04
## ASV0546     -7.925958e-04 -8.266779e-04 -8.620792e-04 -8.988397e-04
## ASV1136      1.929331e-03  2.017161e-03  2.108819e-03  2.204460e-03
## ASV3081      1.014327e-03  1.060929e-03  1.109612e-03  1.160464e-03
## ASV0531      3.084866e-04  3.246831e-04  3.417714e-04  3.598025e-04
## ASV2525      1.501579e-03  1.567778e-03  1.636671e-03  1.708349e-03
## ASV1083     -2.953201e-04 -3.065849e-04 -3.181602e-04 -3.300448e-04
## ASV0424     -2.161476e-04 -2.262590e-04 -2.368331e-04 -2.478897e-04
## ASV0644      1.186229e-04  1.291210e-04  1.404995e-04  1.528258e-04
## ASV6007     -1.186040e-04 -1.291440e-04 -1.405743e-04 -1.529639e-04
## ASV0564      7.199730e-04  7.542591e-04  7.901616e-04  8.277539e-04
## ASV1938      2.218519e-03  2.311042e-03  2.406858e-03  2.506036e-03
## ASV6516     -3.513181e-03 -3.675229e-03 -3.844518e-03 -4.021354e-03
## ASV0503     -1.384472e-03 -1.442848e-03 -1.503361e-03 -1.566064e-03
## ASV6913     -6.976796e-03 -7.290436e-03 -7.617487e-03 -7.958474e-03
## ASV0164     -8.718040e-04 -9.125072e-04 -9.550728e-04 -9.995824e-04
## ASV1576      2.466319e-03  2.578146e-03  2.694829e-03  2.816564e-03
## ASV1725      1.230303e-03  1.289929e-03  1.352440e-03  1.417970e-03
## ASV4501      6.413733e-04  6.663323e-04  6.920085e-04  7.183994e-04
## ASV10678    -3.235885e-03 -3.384448e-03 -3.539582e-03 -3.701557e-03
## ASV0944      5.152736e-04  5.399947e-04  5.659069e-04  5.930679e-04
## ASV2292      2.611701e-03  2.728414e-03  2.850009e-03  2.976660e-03
## ASV1090      1.052382e-03  1.099804e-03  1.149249e-03  1.200797e-03
## ASV9117     -7.155873e-04 -7.433298e-04 -7.718902e-04 -8.012726e-04
## ASV0285     -1.296976e-03 -1.365256e-03 -1.437283e-03 -1.513269e-03
## ASV0463     -7.354334e-04 -7.666348e-04 -7.989896e-04 -8.325257e-04
## ASV3199      9.319614e-04  9.709561e-04  1.011353e-03  1.053183e-03
## ASV0150     -1.539908e-04 -1.623354e-04 -1.711538e-04 -1.804732e-04
## ASV6583     -7.797285e-04 -8.118478e-04 -8.451205e-04 -8.795786e-04
## ASV0392      7.750636e-05  8.054083e-05  8.366301e-05  8.687252e-05
## ASV14007    -1.172059e-03 -1.224305e-03 -1.278716e-03 -1.335368e-03
## ASV0177     -5.507473e-04 -5.750310e-04 -6.003004e-04 -6.265883e-04
## ASV6448     -8.757805e-04 -9.214505e-04 -9.695990e-04 -1.020363e-03
## ASV5399     -5.300773e-03 -5.560483e-03 -5.833064e-03 -6.119152e-03
## ASV0277     -1.216308e-04 -1.268886e-04 -1.323445e-04 -1.380031e-04
## ASV2599      6.078928e-04  6.180830e-04  6.272763e-04  6.353244e-04
## ASV13465    -3.691125e-04 -3.815029e-04 -3.940756e-04 -4.068115e-04
## ASV2412      3.063552e-04  3.204863e-04  3.352487e-04  3.506689e-04
## ASV0423     -1.056533e-04 -1.089546e-04 -1.122600e-04 -1.155570e-04
## ASV5187      1.554063e-03  1.613959e-03  1.675579e-03  1.738925e-03
## ASV0701     -1.046071e-03 -1.094737e-03 -1.145615e-03 -1.198798e-03
## ASV4248      5.752028e-04  6.039533e-04  6.341682e-04  6.659217e-04
## ASV0519      9.907984e-04  1.037671e-03  1.086732e-03  1.138077e-03
## ASV0764      2.626586e-04  2.752794e-04  2.885028e-04  3.023564e-04
## ASV5385     -8.833088e-04 -9.247850e-04 -9.681827e-04 -1.013589e-03
## ASV3021     -1.474756e-03 -1.533964e-03 -1.595117e-03 -1.658246e-03
## ASV4119     -3.885167e-03 -4.061495e-03 -4.245515e-03 -4.437544e-03
## ASV2534     -1.734257e-04 -1.846068e-04 -1.965437e-04 -2.092867e-04
## ASV1061      9.978969e-04  1.048023e-03  1.100751e-03  1.156220e-03
## ASV0670     -2.642932e-04 -2.764950e-04 -2.892415e-04 -3.025551e-04
## ASV1384      1.159048e-03  1.216439e-03  1.276703e-03  1.339981e-03
## ASV1981      2.783554e-03  2.914757e-03  3.052058e-03  3.195728e-03
## ASV9632     -5.473498e-04 -5.652701e-04 -5.834157e-04 -6.017560e-04
## ASV4564      8.162302e-04  8.538891e-04  8.932223e-04  9.342980e-04
## ASV5289     -5.166222e-04 -5.421890e-04 -5.690594e-04 -5.973028e-04
## ASV0516      1.931073e-03  2.019735e-03  2.112308e-03  2.208949e-03
## ASV1463     -2.707583e-03 -2.831519e-03 -2.960907e-03 -3.095967e-03
## ASV0969      1.027064e-04  1.068722e-04  1.111709e-04  1.156031e-04
## ASV1113     -6.187101e-04 -6.472711e-04 -6.771096e-04 -7.082788e-04
## ASV1234     -7.612806e-04 -8.017450e-04 -8.445110e-04 -8.897196e-04
## ASV3814     -4.797927e-04 -5.119667e-04 -5.463873e-04 -5.832079e-04
## ASV1000      1.231601e-03  1.286557e-03  1.343793e-03  1.403389e-03
## ASV0079     -1.369180e-04 -1.442874e-04 -1.520778e-04 -1.603144e-04
## ASV0145      2.208984e-04  2.288278e-04  2.369310e-04  2.452024e-04
## ASV0457     -1.605164e-03 -1.677407e-03 -1.752713e-03 -1.831197e-03
## ASV1485      1.295077e-04  1.358528e-04  1.425159e-04  1.495133e-04
## ASV0535      4.976580e-04  5.232917e-04  5.502912e-04  5.787303e-04
## ASV0259     -8.973043e-04 -9.381834e-04 -9.808346e-04 -1.025326e-03
## ASV0570      2.790828e-04  2.931166e-04  3.078803e-04  3.234132e-04
## ASV0906      1.026334e-03  1.071825e-03  1.119182e-03  1.168468e-03
## ASV1748      9.610929e-04  9.920573e-04  1.023243e-03  1.054563e-03
## ASV5520     -1.379584e-03 -1.450679e-03 -1.525564e-03 -1.604444e-03
## ASV2288     -3.394930e-03 -3.550949e-03 -3.713882e-03 -3.884015e-03
## ASV1887     -7.155727e-04 -7.555482e-04 -7.978428e-04 -8.425884e-04
## ASV0374     -1.394937e-04 -1.447836e-04 -1.502151e-04 -1.557870e-04
## ASV0823      1.972618e-03  2.059069e-03  2.149005e-03  2.242542e-03
## ASV0717      1.481857e-04  1.550696e-04  1.622635e-04  1.697805e-04
## ASV0431     -4.040053e-04 -4.231360e-04 -4.431657e-04 -4.641358e-04
## ASV1030      4.637086e-03  4.856428e-03  5.086041e-03  5.326395e-03
## ASV1082     -6.031404e-04 -6.312719e-04 -6.606862e-04 -6.914391e-04
## ASV2684      1.033505e-04  1.114633e-04  1.201825e-04  1.295479e-04
## ASV0051      5.748850e-04  6.016263e-04  6.295847e-04  6.588133e-04
## ASV0513     -1.790144e-04 -1.866903e-04 -1.946548e-04 -2.029149e-04
## ASV0581      1.048149e-03  1.096627e-03  1.147276e-03  1.200186e-03
## ASV7282      3.476193e-04  3.671597e-04  3.878864e-04  4.098764e-04
## ASV3009     -8.965194e-04 -9.378752e-04 -9.810760e-04 -1.026198e-03
## ASV2106      1.083799e-03  1.141451e-03  1.202327e-03  1.266615e-03
## ASV1012      7.596939e-04  7.956498e-04  8.332761e-04  8.726462e-04
## ASV0921      7.689588e-04  8.061091e-04  8.450749e-04  8.859464e-04
## ASV0010     -4.492548e-04 -4.702369e-04 -4.921763e-04 -5.151145e-04
## ASV1178      2.050216e-04  2.149286e-04  2.253093e-04  2.361850e-04
## ASV2848     -1.197462e-03 -1.251203e-03 -1.307237e-03 -1.365654e-03
## ASV0586      2.995979e-03  3.137927e-03  3.286563e-03  3.442200e-03
## ASV4225     -4.327370e-03 -4.481831e-03 -4.639653e-03 -4.800732e-03
## ASV2156     -1.681636e-03 -1.760519e-03 -1.843045e-03 -1.929375e-03
## ASV9778     -1.206670e-03 -1.262651e-03 -1.321162e-03 -1.382311e-03
## ASV0493     -2.456156e-03 -2.566731e-03 -2.682022e-03 -2.802208e-03
## ASV3770     -3.136664e-04 -3.336266e-04 -3.549218e-04 -3.776400e-04
## ASV0470      1.721501e-03  1.801315e-03  1.884734e-03  1.971912e-03
## ASV0262     -7.438093e-04 -7.816641e-04 -8.215073e-04 -8.634455e-04
## ASV0998      4.498634e-04  4.710445e-04  4.932112e-04  5.164084e-04
## ASV7708     -2.148025e-04 -2.238133e-04 -2.331429e-04 -2.427970e-04
## ASV0453     -1.766636e-04 -1.847575e-04 -1.932156e-04 -2.020544e-04
## ASV0044      7.195789e-04  7.525980e-04  7.870747e-04  8.230683e-04
## ASV5490      4.081419e-04  4.253681e-04  4.432082e-04  4.616723e-04
## ASV2638     -2.363087e-04 -2.458898e-04 -2.558107e-04 -2.660820e-04
## ASV0829      2.481836e-03  2.595508e-03  2.714114e-03  2.837840e-03
## ASV0601      8.307794e-04  8.704709e-04  9.120571e-04  9.556276e-04
## ASV0234      6.393645e-05  6.723577e-05  7.071537e-05  7.438587e-05
## ASV0133      1.261598e-03  1.320127e-03  1.381298e-03  1.445224e-03
## ASV0323      4.161335e-04  4.362692e-04  4.573921e-04  4.795516e-04
## ASV0854     -2.863825e-04 -2.994698e-04 -3.131307e-04 -3.273884e-04
## ASV0110      7.956120e-04  8.327381e-04  8.715618e-04  9.121576e-04
## ASV0816     -7.900263e-05 -8.277085e-05 -8.671786e-05 -9.085197e-05
## ASV1031     -2.932813e-04 -3.058626e-04 -3.189314e-04 -3.325030e-04
## ASV0144     -3.680518e-04 -3.856063e-04 -4.040014e-04 -4.232777e-04
## ASV0020     -1.721381e-04 -1.806919e-04 -1.896860e-04 -1.991445e-04
## ASV0962     -4.716582e-04 -4.932721e-04 -5.158360e-04 -5.393878e-04
## ASV0794      8.886946e-04  9.324435e-04  9.783723e-04  1.026589e-03
## ASV7117     -8.227607e-04 -8.599417e-04 -8.987143e-04 -9.391390e-04
## ASV1008     -3.996762e-04 -4.188970e-04 -4.390472e-04 -4.601716e-04
## ASV0096      1.018357e-03  1.065829e-03  1.115467e-03  1.167365e-03
## ASV0128     -1.683547e-03 -1.763928e-03 -1.848152e-03 -1.936403e-03
## ASV5232      1.553104e-03  1.628503e-03  1.707589e-03  1.790542e-03
## ASV0031     -1.198903e-04 -1.255561e-04 -1.314861e-04 -1.376922e-04
## ASV1744     -1.632065e-03 -1.709172e-03 -1.789923e-03 -1.874492e-03
## ASV0289      4.588495e-04  4.801742e-04  5.024682e-04  5.257740e-04
## ASV7413     -2.718061e-04 -2.877922e-04 -3.047824e-04 -3.228414e-04
## ASV0822     -2.020365e-03 -2.110735e-03 -2.204889e-03 -2.302963e-03
## ASV8111     -3.339609e-03 -3.489049e-03 -3.644825e-03 -3.807180e-03
## ASV0687      4.376512e-04  4.585666e-04  4.804757e-04  5.034245e-04
## ASV0112     -1.598489e-04 -1.675392e-04 -1.756010e-04 -1.840520e-04
## ASV0987      5.412371e-04  5.672360e-04  5.944914e-04  6.230645e-04
## ASV5332     -3.242489e-04 -3.350116e-04 -3.459587e-04 -3.570822e-04
## ASV1129     -9.903614e-04 -1.036552e-03 -1.084858e-03 -1.135372e-03
## ASV1274     -2.735433e-04 -2.861711e-04 -2.993644e-04 -3.131468e-04
## ASV0119      6.603107e-04  6.910476e-04  7.231829e-04  7.567773e-04
## ASV0890     -3.525176e-05 -3.707738e-05 -3.900713e-05 -4.104797e-05
## ASV0848     -1.226126e-03 -1.283181e-03 -1.342831e-03 -1.405190e-03
## ASV5944     -5.380129e-03 -5.626075e-03 -5.882806e-03 -6.150757e-03
## ASV19741    -1.963122e-03 -2.053346e-03 -2.147572e-03 -2.245965e-03
## ASV0504     -2.467458e-03 -2.578009e-03 -2.693222e-03 -2.813270e-03
## ASV2146     -1.777045e-03 -1.854768e-03 -1.935627e-03 -2.019727e-03
## ASV0089     -4.183368e-04 -4.376318e-04 -4.577860e-04 -4.788346e-04
## ASV2301     -6.799865e-04 -7.119500e-04 -7.453946e-04 -7.803867e-04
## ASV2982     -1.163436e-02 -1.208992e-02 -1.255950e-02 -1.304326e-02
## ASV0891     -7.921959e-04 -8.288233e-04 -8.670939e-04 -9.070769e-04
## ASV0093      8.648101e-04  9.044874e-04  9.459193e-04  9.891777e-04
## ASV0042      3.036120e-04  3.177574e-04  3.325479e-04  3.480119e-04
## ASV0980      9.752732e-04  1.017914e-03  1.062241e-03  1.108306e-03
## ASV0069     -4.635281e-04 -4.850976e-04 -5.076457e-04 -5.312143e-04
## ASV1364     -3.545700e-04 -3.706906e-04 -3.875090e-04 -4.050523e-04
## ASV0524     -1.786600e-03 -1.870903e-03 -1.959146e-03 -2.051508e-03
## ASV0435      2.445294e-03  2.559800e-03  2.679578e-03  2.804860e-03
## ASV0517     -4.823716e-04 -5.048758e-04 -5.284085e-04 -5.530147e-04
## ASV3167     -3.522666e-03 -3.700409e-03 -3.887376e-03 -4.084054e-03
## ASV4280     -2.203780e-03 -2.305832e-03 -2.412485e-03 -2.523935e-03
## ASV1158      7.926667e-04  8.324436e-04  8.742342e-04  9.181371e-04
## ASV2214      7.333413e-04  7.659039e-04  7.998461e-04  8.352243e-04
## ASV0544     -1.202274e-03 -1.259539e-03 -1.319529e-03 -1.382372e-03
## ASV5326     -1.683426e-04 -1.765366e-04 -1.851377e-04 -1.941668e-04
## ASV3765     -9.322891e-04 -9.752941e-04 -1.020218e-03 -1.067139e-03
## ASV4646     -3.295672e-06 -6.984274e-06 -1.112760e-05 -1.576640e-05
## ASV0090      7.141437e-05  7.429836e-05  7.727332e-05  8.033963e-05
## ASV3680      1.529357e-03  1.595637e-03  1.664496e-03  1.736010e-03
## ASV0111      1.611586e-04  1.683125e-04  1.757604e-04  1.835123e-04
## ASV0768      2.336354e-04  2.449787e-04  2.568816e-04  2.693724e-04
## ASV4862     -1.285333e-04 -1.329848e-04 -1.374943e-04 -1.420507e-04
## ASV1742     -1.354220e-03 -1.415272e-03 -1.478942e-03 -1.545330e-03
## ASV3701     -4.961862e-04 -5.161661e-04 -5.368070e-04 -5.581201e-04
## ASV2386     -2.594728e-03 -2.717185e-03 -2.845337e-03 -2.979438e-03
## ASV0375     -1.824579e-03 -1.907226e-03 -1.993450e-03 -2.083394e-03
## ASV2796      6.248273e-04  6.516119e-04  6.794364e-04  7.083341e-04
## ASV1369      1.406483e-03  1.468487e-03  1.533077e-03  1.600352e-03
## ASV10272    -2.067268e-03 -2.162289e-03 -2.261511e-03 -2.365106e-03
## ASV10354    -3.078451e-03 -3.219933e-03 -3.367670e-03 -3.521914e-03
## ASV1067      1.006929e-03  1.052722e-03  1.100506e-03  1.150360e-03
## ASV1900      1.659738e-03  1.737425e-03  1.818685e-03  1.903676e-03
## ASV4079     -7.641900e-04 -8.021802e-04 -8.421008e-04 -8.840510e-04
## ASV4149      3.229539e-03  3.371055e-03  3.518223e-03  3.671219e-03
## ASV5140     -3.078212e-03 -3.219671e-03 -3.367382e-03 -3.521598e-03
## ASV10782     1.144833e-04  1.224698e-04  1.310719e-04  1.403402e-04
## ASV4273     -2.852465e-04 -2.959653e-04 -3.069262e-04 -3.181161e-04
## ASV8121      1.387779e-03  1.452109e-03  1.519348e-03  1.589621e-03
## ASV8438     -3.501995e-03 -3.662916e-03 -3.830948e-03 -4.006380e-03
## ASV9390     -3.501590e-03 -3.662473e-03 -3.830464e-03 -4.005851e-03
## ASV1340      2.831782e-03  2.964316e-03  3.102938e-03  3.247916e-03
## ASV2650     -6.500561e-03 -6.797068e-03 -7.106482e-03 -7.429309e-03
## ASV4674      1.735392e-03  1.814632e-03  1.897329e-03  1.983620e-03
## ASV10492     2.454704e-05  2.470558e-05  2.477972e-05  2.475740e-05
## ASV11430    -2.671952e-03 -2.794697e-03 -2.922864e-03 -3.056671e-03
## ASV12135    -2.671643e-03 -2.794360e-03 -2.922495e-03 -3.056267e-03
## ASV14970    -3.285281e-03 -3.436165e-03 -3.593710e-03 -3.758184e-03
## ASV1954      3.994129e-03  4.178275e-03  4.370626e-03  4.571519e-03
## ASV2613      2.523028e-03  2.638559e-03  2.759167e-03  2.885059e-03
## ASV2757      1.555877e-03  1.624237e-03  1.695347e-03  1.769296e-03
## ASV2909     -4.722151e-03 -4.945407e-03 -5.179132e-03 -5.423811e-03
## ASV2954     -1.769744e-04 -1.851670e-04 -1.937248e-04 -2.026626e-04
## ASV2969      1.205624e-03  1.262189e-03  1.321366e-03  1.383274e-03
## ASV3410      4.287285e-04  4.492668e-04  4.707962e-04  4.933651e-04
## ASV3575      8.116054e-04  8.482832e-04  8.865374e-04  9.264293e-04
## ASV4275      2.075037e-03  2.167181e-03  2.263113e-03  2.362962e-03
## ASV4652      4.522595e-04  4.737471e-04  4.962521e-04  5.198220e-04
## ASV4761      1.503372e-03  1.569917e-03  1.639172e-03  1.711225e-03
## ASV6003      1.118798e-03  1.172618e-03  1.229049e-03  1.288219e-03
## ASV6110     -7.538899e-03 -7.885227e-03 -8.246851e-03 -8.624390e-03
## ASV7427      1.305312e-03  1.364217e-03  1.425634e-03  1.489657e-03
## ASV8092     -2.472114e-03 -2.585670e-03 -2.704242e-03 -2.828030e-03
## ASV8169     -7.537456e-03 -7.883648e-03 -8.245123e-03 -8.622500e-03
## ASV9693      1.277731e-03  1.336100e-03  1.397019e-03  1.460587e-03
## ASV10913     8.629298e-04  9.034875e-04  9.459255e-04  9.903283e-04
## ASV1979      7.564870e-04  7.904317e-04  8.257997e-04  8.626414e-04
## ASV3772      1.562510e-03  1.632564e-03  1.705566e-03  1.781626e-03
## ASV0113     -2.115377e-04 -2.214683e-04 -2.318565e-04 -2.427226e-04
## ASV1800     -2.798479e-04 -2.930702e-04 -3.069046e-04 -3.213780e-04
## ASV2335     -5.775136e-03 -6.036982e-03 -6.310206e-03 -6.595268e-03
## ASV0692     -3.971172e-05 -4.168058e-05 -4.375208e-05 -4.593211e-05
## ASV1120      2.103725e-04  2.203859e-04  2.308759e-04  2.418652e-04
## ASV1434     -1.041175e-03 -1.089714e-03 -1.140468e-03 -1.193534e-03
## ASV0076     -4.875885e-04 -5.102458e-04 -5.339280e-04 -5.586789e-04
## ASV0361      1.743304e-03  1.824897e-03  1.910243e-03  1.999508e-03
## ASV2231     -5.684607e-04 -5.968404e-04 -6.266849e-04 -6.580729e-04
## ASV2018     -1.398649e-04 -1.463700e-04 -1.531717e-04 -1.602831e-04
## ASV1529      7.579382e-04  7.940670e-04  8.319176e-04  8.715717e-04
## ASV0841     -2.625985e-04 -2.746544e-04 -2.872433e-04 -3.003872e-04
## ASV2556     -4.828058e-03 -5.051890e-03 -5.285807e-03 -5.530238e-03
## ASV2777      1.575377e-03  1.642727e-03  1.712607e-03  1.785082e-03
## ASV0355      1.202311e-03  1.257898e-03  1.315980e-03  1.376663e-03
## ASV5169     -1.436776e-03 -1.502905e-03 -1.571967e-03 -1.644083e-03
## ASV3091      1.360226e-03  1.424424e-03  1.491625e-03  1.561967e-03
## ASV2435      5.467684e-04  5.718194e-04  5.979711e-04  6.252674e-04
## ASV6822     -2.960805e-03 -3.096859e-03 -3.238926e-03 -3.387250e-03
## ASV12605    -2.891934e-03 -3.027019e-03 -3.168285e-03 -3.316004e-03
## ASV0286     -6.928667e-04 -7.248400e-04 -7.582527e-04 -7.931672e-04
## ASV0074     -2.747294e-04 -2.876277e-04 -3.011210e-04 -3.152357e-04
## ASV2485     -1.192425e-04 -1.258213e-04 -1.328046e-04 -1.402205e-04
## ASV1233     -2.172383e-03 -2.274059e-03 -2.380418e-03 -2.491668e-03
## ASV0356     -5.725243e-04 -5.985492e-04 -6.257083e-04 -6.540475e-04
## ASV2918     -2.411586e-03 -2.522413e-03 -2.638156e-03 -2.759015e-03
## ASV1427     -3.054654e-04 -3.203946e-04 -3.360714e-04 -3.525348e-04
## ASV1409      5.355868e-04  5.611289e-04  5.878892e-04  6.159257e-04
## ASV0770      1.655786e-04  1.728280e-04  1.803646e-04  1.881970e-04
## ASV1403     -1.486612e-03 -1.555277e-03 -1.627016e-03 -1.701958e-03
## ASV0314     -5.130584e-04 -5.361485e-04 -5.602115e-04 -5.852821e-04
## ASV0187     -1.523529e-04 -1.596394e-04 -1.672707e-04 -1.752623e-04
## ASV0313     -7.303832e-04 -7.636283e-04 -7.983144e-04 -8.344974e-04
## ASV1087      1.688421e-03  1.766598e-03  1.848293e-03  1.933656e-03
## ASV1970     -2.563648e-04 -2.681424e-04 -2.804393e-04 -2.932760e-04
## ASV0754      1.860431e-03  1.947092e-03  2.037700e-03  2.132428e-03
## ASV3775     -4.454502e-04 -4.664035e-04 -4.883301e-04 -5.112737e-04
## ASV0132     -3.206355e-04 -3.355251e-04 -3.510887e-04 -3.673551e-04
## ASV2329      1.608616e-04  1.641611e-04  1.672681e-04  1.701489e-04
## ASV0561      4.688608e-04  4.894514e-04  5.108586e-04  5.331060e-04
## ASV0130     -9.692939e-04 -1.014421e-03 -1.061599e-03 -1.110914e-03
## ASV0226      1.219523e-03  1.275764e-03  1.334513e-03  1.395871e-03
## ASV12648    -1.705568e-03 -1.782929e-03 -1.863656e-03 -1.947883e-03
## ASV0204      1.173646e-03  1.227784e-03  1.284337e-03  1.343404e-03
## ASV0767     -5.746292e-04 -6.026623e-04 -6.320924e-04 -6.629914e-04
## ASV0335     -1.091949e-03 -1.142116e-03 -1.194500e-03 -1.249189e-03
## ASV5901     -2.372187e-04 -2.475959e-04 -2.583951e-04 -2.696313e-04
## ASV0596      3.644380e-06  4.819871e-06  6.141494e-06  7.623951e-06
## ASV9271      8.984154e-04  9.438499e-04  9.916391e-04  1.041906e-03
## ASV0904      7.115090e-04  7.452378e-04  7.805562e-04  8.175382e-04
## ASV15270    -4.735650e-04 -4.980644e-04 -5.238686e-04 -5.510468e-04
## ASV0990     -3.927438e-04 -4.112318e-04 -4.305799e-04 -4.508273e-04
## ASV0155     -8.128255e-04 -8.504545e-04 -8.897746e-04 -9.308569e-04
## ASV0086     -1.622552e-04 -1.697946e-04 -1.776755e-04 -1.859123e-04
## ASV2581     -7.703789e-05 -8.026849e-05 -8.361059e-05 -8.706543e-05
## ASV1579     -6.681257e-04 -6.999458e-04 -7.332779e-04 -7.681930e-04
## ASV7730     -4.413856e-05 -4.787816e-05 -5.190754e-05 -5.624549e-05
## ASV0897      1.006122e-04  1.055329e-04  1.106989e-04  1.161227e-04
## ASV1975      4.552850e-03  4.764043e-03  4.984786e-03  5.215491e-03
##                                                                    
## (Intercept)  1.696556e-02  1.774923e-02  1.856784e-02  1.942281e-02
## ASV1236      2.714752e-03  2.835329e-03  2.960858e-03  3.091508e-03
## ASV0421     -1.280742e-03 -1.337022e-03 -1.395561e-03 -1.456432e-03
## ASV0691     -2.593246e-03 -2.702050e-03 -2.814762e-03 -2.931467e-03
## ASV0899      1.603521e-03  1.678242e-03  1.756341e-03  1.837959e-03
## ASV1004      6.123504e-03  6.396791e-03  6.681431e-03  6.977818e-03
## ASV1041     -3.753876e-03 -3.922987e-03 -4.099249e-03 -4.282922e-03
## ASV1058      3.816212e-03  3.986657e-03  4.164204e-03  4.349104e-03
## ASV12542     1.431578e-03  1.494205e-03  1.559332e-03  1.627038e-03
## ASV1294      3.214467e-03  3.358767e-03  3.509142e-03  3.665813e-03
## ASV13113     1.163204e-03  1.218901e-03  1.277280e-03  1.338469e-03
## ASV1318      3.517791e-03  3.675337e-03  3.839476e-03  4.010444e-03
## ASV2269     -5.988796e-03 -6.258992e-03 -6.540604e-03 -6.834040e-03
## ASV2542      2.664012e-03  2.788268e-03  2.918191e-03  3.054029e-03
## ASV2660     -2.655635e-03 -2.774047e-03 -2.897355e-03 -3.025728e-03
## ASV2737      4.779922e-04  4.971798e-04  5.169876e-04  5.374234e-04
## ASV2840      3.320092e-03  3.465912e-03  3.617569e-03  3.775248e-03
## ASV3053      2.804930e-02  2.929311e-02  3.058798e-02  3.193563e-02
## ASV3077      9.873408e-04  1.031004e-03  1.076456e-03  1.123760e-03
## ASV3134      1.925661e-03  2.016555e-03  2.111703e-03  2.211302e-03
## ASV3140      2.332067e-03  2.439597e-03  2.551895e-03  2.669154e-03
## ASV3579      7.717691e-04  8.091962e-04  8.484681e-04  8.896778e-04
## ASV6119     -1.634424e-03 -1.708150e-03 -1.784991e-03 -1.865057e-03
## ASV7557     -3.324563e-03 -3.474509e-03 -3.630785e-03 -3.793619e-03
## ASV8422      7.218190e-04  7.526869e-04  7.847325e-04  8.179896e-04
## ASV1086     -1.710367e-04 -1.781714e-04 -1.855673e-04 -1.932315e-04
## ASV1310      1.413571e-03  1.476638e-03  1.542324e-03  1.610720e-03
## ASV15750    -2.416427e-04 -2.522547e-04 -2.632817e-04 -2.747345e-04
## ASV16905    -6.825080e-04 -7.132895e-04 -7.453707e-04 -7.787979e-04
## ASV2033      3.023483e-03  3.163619e-03  3.310071e-03  3.463107e-03
## ASV2089      1.248927e-03  1.305441e-03  1.364354e-03  1.425752e-03
## ASV2127      4.704606e-03  4.914385e-03  5.132869e-03  5.360361e-03
## ASV2725      3.757132e-03  3.922291e-03  4.094093e-03  4.272748e-03
## ASV2804     -1.413464e-03 -1.477209e-03 -1.543644e-03 -1.612867e-03
## ASV3075      3.167875e-03  3.310480e-03  3.459154e-03  3.614125e-03
## ASV3327      4.347694e-03  4.548759e-03  4.758856e-03  4.978369e-03
## ASV3342      3.576749e-03  3.741156e-03  3.912829e-03  4.092060e-03
## ASV3532     -4.073514e-03 -4.261349e-03 -4.457531e-03 -4.662401e-03
## ASV3600      1.830993e-03  1.914350e-03  2.001334e-03  2.092090e-03
## ASV4013      3.527278e-03  3.685734e-03  3.850878e-03  4.022954e-03
## ASV4136      3.862300e-03  4.032326e-03  4.209206e-03  4.393160e-03
## ASV4195      1.428653e-02  1.493071e-02  1.560209e-02  1.630161e-02
## ASV4407     -5.588029e-03 -5.839960e-03 -6.102519e-03 -6.376085e-03
## ASV4717      5.250787e-04  5.447100e-04  5.648489e-04  5.854896e-04
## ASV6794      2.165403e-03  2.257597e-03  2.353253e-03  2.452465e-03
## ASV8324     -2.862416e-03 -2.991460e-03 -3.125948e-03 -3.266073e-03
## ASV8981     -9.591270e-05 -9.953790e-05 -1.032445e-04 -1.070278e-04
## ASV9859      8.904467e-04  9.346939e-04  9.812235e-04  1.030160e-03
## ASV0936      2.318682e-04  2.438654e-04  2.564924e-04  2.697811e-04
## ASV12683    -7.407726e-05 -7.822683e-05 -8.261175e-05 -8.724441e-05
## ASV1293      1.794775e-03  1.874597e-03  1.957708e-03  2.044221e-03
## ASV13055    -9.451314e-05 -9.815258e-05 -1.018743e-04 -1.056730e-04
## ASV17063    -1.483647e-03 -1.550509e-03 -1.620190e-03 -1.692788e-03
## ASV2228      1.207807e-03  1.262230e-03  1.318947e-03  1.378038e-03
## ASV2769      1.230537e-04  1.290696e-04  1.353921e-04  1.420379e-04
## ASV2803      1.061357e-03  1.106478e-03  1.153287e-03  1.201829e-03
## ASV2896      1.009896e-03  1.056363e-03  1.104908e-03  1.155619e-03
## ASV3062      1.094431e-03  1.146365e-03  1.200760e-03  1.257733e-03
## ASV3107      2.024595e-03  2.117976e-03  2.215534e-03  2.317443e-03
## ASV3265      2.769661e-03  2.892838e-03  3.021097e-03  3.154611e-03
## ASV3666      8.911220e-06  9.108434e-06  9.304262e-06  9.498656e-06
## ASV4497      8.442140e-04  8.820603e-04  9.215056e-04  9.626094e-04
## ASV6914     -2.064939e-04 -2.167389e-04 -2.274948e-04 -2.387863e-04
## ASV0576     -3.536892e-03 -3.688907e-03 -3.846731e-03 -4.010523e-03
## ASV0673      2.661550e-03  2.783688e-03  2.911209e-03  3.044330e-03
## ASV0772      1.530394e-03  1.599320e-03  1.671182e-03  1.746092e-03
## ASV0862     -2.362874e-04 -2.444842e-04 -2.528180e-04 -2.612764e-04
## ASV0898      1.125951e-03  1.178970e-03  1.234442e-03  1.292476e-03
## ASV0910      1.386569e-03  1.450961e-03  1.518268e-03  1.588615e-03
## ASV0964     -1.415824e-03 -1.478094e-03 -1.542884e-03 -1.610278e-03
## ASV10059     9.893662e-04  1.036698e-03  1.086309e-03  1.138310e-03
## ASV10263    -2.260774e-03 -2.362734e-03 -2.469000e-03 -2.579724e-03
## ASV1088      2.228291e-03  2.331403e-03  2.439167e-03  2.551784e-03
## ASV1101      2.623708e-03  2.740869e-03  2.862901e-03  2.989977e-03
## ASV1183      8.024282e-04  8.394610e-04  8.781399e-04  9.185319e-04
## ASV11956     6.895858e-04  7.177919e-04  7.469589e-04  7.771041e-04
## ASV12774    -1.725783e-05 -1.919271e-05 -2.130652e-05 -2.361374e-05
## ASV1321      3.455740e-03  3.616536e-03  3.784643e-03  3.960381e-03
## ASV13793    -1.558016e-03 -1.628274e-03 -1.701498e-03 -1.777793e-03
## ASV14482     1.141625e-05  1.069352e-05  9.842874e-06  8.852600e-06
## ASV15483     5.797480e-04  6.065501e-04  6.345624e-04  6.638375e-04
## ASV2062      2.883408e-03  3.013706e-03  3.149574e-03  3.291220e-03
## ASV2132      2.521155e-03  2.638085e-03  2.760302e-03  2.888031e-03
## ASV2413      2.265210e-03  2.365843e-03  2.470626e-03  2.579704e-03
## ASV2490      6.998641e-03  7.302871e-03  7.619013e-03  7.947422e-03
## ASV2594      8.195887e-04  8.566425e-04  8.952979e-04  9.356191e-04
## ASV2822     -4.118069e-03 -4.303822e-03 -4.497422e-03 -4.699147e-03
## ASV2863      4.442748e-03  4.638913e-03  4.843031e-03  5.055364e-03
## ASV2910      1.540588e-03  1.608650e-03  1.679484e-03  1.753183e-03
## ASV2980      1.499492e-03  1.567461e-03  1.638334e-03  1.712220e-03
## ASV3307      3.261473e-03  3.408549e-03  3.561834e-03  3.721549e-03
## ASV3474      1.991489e-03  2.084662e-03  2.182120e-03  2.284051e-03
## ASV3502      2.394343e-03  2.503501e-03  2.617418e-03  2.736282e-03
## ASV4236      3.461277e-03  3.613818e-03  3.772529e-03  3.937609e-03
## ASV4842     -6.887413e-04 -7.220547e-04 -7.569512e-04 -7.935002e-04
## ASV4894     -1.558282e-03 -1.628565e-03 -1.701817e-03 -1.778142e-03
## ASV5290      1.240535e-03  1.297187e-03  1.356324e-03  1.418045e-03
## ASV5501      6.191495e-04  6.472849e-04  6.766560e-04  7.073144e-04
## ASV5795      7.588061e-04  7.935452e-04  8.298180e-04  8.676874e-04
## ASV5987     -4.360059e-03 -4.556732e-03 -4.761712e-03 -4.975298e-03
## ASV6267     -4.914234e-03 -5.135872e-03 -5.366871e-03 -5.607563e-03
## ASV6862      1.999520e-03  2.086175e-03  2.176210e-03  2.269725e-03
## ASV7145      7.442858e-04  7.747535e-04  8.062649e-04  8.388397e-04
## ASV7673     -1.558151e-03 -1.628422e-03 -1.701661e-03 -1.777972e-03
## ASV7789      6.633270e-04  6.954640e-04  7.291860e-04  7.645734e-04
## ASV7809     -2.812099e-05 -2.876232e-05 -2.936323e-05 -2.991496e-05
## ASV8002     -1.968315e-03 -2.057080e-03 -2.149592e-03 -2.245986e-03
## ASV8205      6.621211e-04  6.918326e-04  7.228108e-04  7.551048e-04
## ASV9155     -5.404395e-04 -5.645679e-04 -5.896869e-04 -6.158287e-04
## ASV9221      4.740279e-05  4.929789e-05  5.125879e-05  5.328721e-05
## ASV9311     -3.159618e-03 -3.302086e-03 -3.450569e-03 -3.605279e-03
## ASV9557     -2.157862e-03 -2.255147e-03 -2.356537e-03 -2.462179e-03
## ASV9936     -4.357232e-03 -4.553646e-03 -4.758346e-03 -4.971625e-03
## ASV1445      2.861825e-03  2.992931e-03  3.129811e-03  3.272698e-03
## ASV4232      1.272592e-03  1.332302e-03  1.394783e-03  1.460159e-03
## ASV6479      2.037393e-04  2.159990e-04  2.290817e-04  2.430480e-04
## ASV0142     -1.797810e-03 -1.877123e-03 -1.959654e-03 -2.045509e-03
## ASV0378     -7.108518e-05 -7.254856e-05 -7.390954e-05 -7.514843e-05
## ASV1122      2.818123e-03  2.947737e-03  3.083106e-03  3.224467e-03
## ASV0123     -1.590514e-03 -1.660576e-03 -1.733471e-03 -1.809290e-03
## ASV2064      9.062410e-04  9.447987e-04  9.848167e-04  1.026337e-03
## ASV4459     -4.083480e-04 -4.275015e-04 -4.475265e-04 -4.684596e-04
## ASV0448      6.135381e-04  6.429990e-04  6.738753e-04  7.062341e-04
## ASV0397      1.308130e-03  1.367981e-03  1.430453e-03  1.495653e-03
## ASV0485      1.709915e-03  1.786800e-03  1.866935e-03  1.950441e-03
## ASV1566      2.718865e-03  2.842406e-03  2.971291e-03  3.105729e-03
## ASV1365      1.736537e-03  1.814548e-03  1.895853e-03  1.980573e-03
## ASV1065      3.267791e-03  3.417111e-03  3.572963e-03  3.735606e-03
## ASV0722     -1.889175e-04 -1.976934e-04 -2.068757e-04 -2.164837e-04
## ASV12660    -1.784496e-03 -1.863560e-03 -1.945848e-03 -2.031465e-03
## ASV0223      2.744251e-04  2.869199e-04  2.999546e-04  3.135500e-04
## ASV0229      6.832171e-04  7.150231e-04  7.482716e-04  7.830242e-04
## ASV0877      5.974755e-05  6.128650e-05  6.280386e-05  6.429292e-05
## ASV0983      1.730288e-03  1.807416e-03  1.887736e-03  1.971358e-03
## ASV0626     -1.214660e-04 -1.245574e-04 -1.275603e-04 -1.304511e-04
## ASV4146     -9.806113e-05 -1.030783e-04 -1.083609e-04 -1.139235e-04
## ASV4175     -2.094117e-03 -2.190228e-03 -2.290570e-03 -2.395312e-03
## ASV2082     -9.937019e-04 -1.042554e-03 -1.093881e-03 -1.147815e-03
## ASV2272      9.492945e-04  9.921632e-04  1.036869e-03  1.083483e-03
## ASV2245     -1.525864e-03 -1.596023e-03 -1.669281e-03 -1.745762e-03
## ASV0590     -1.280757e-03 -1.343884e-03 -1.410212e-03 -1.479911e-03
## ASV0217     -1.474197e-04 -1.507138e-04 -1.538435e-04 -1.567750e-04
## ASV0416      1.174821e-03  1.224861e-03  1.276755e-03  1.330545e-03
## ASV1056      1.358868e-03  1.422516e-03  1.489093e-03  1.558731e-03
## ASV7777     -2.042761e-03 -2.137609e-03 -2.236742e-03 -2.340343e-03
## ASV0455      2.582654e-04  2.699814e-04  2.821967e-04  2.949291e-04
## ASV0604      8.290772e-04  8.687884e-04  9.104042e-04  9.540152e-04
## ASV6100     -1.449311e-03 -1.516705e-03 -1.587152e-03 -1.660783e-03
## ASV11359    -3.228322e-03 -3.374815e-03 -3.527595e-03 -3.686898e-03
## ASV6604      5.831007e-04  6.105154e-04  6.392043e-04  6.692253e-04
## ASV5004     -9.223030e-04 -9.648761e-04 -1.009346e-03 -1.055792e-03
## ASV1483     -5.818010e-04 -6.089983e-04 -6.374356e-04 -6.671662e-04
## ASV9773     -1.444695e-03 -1.511414e-03 -1.581111e-03 -1.653913e-03
## ASV4059      1.076193e-03  1.128445e-03  1.183276e-03  1.240816e-03
## ASV1193      1.753298e-03  1.832965e-03  1.916080e-03  2.002777e-03
## ASV4610     -2.328576e-04 -2.409535e-04 -2.491709e-04 -2.574942e-04
## ASV0742     -3.857712e-04 -4.008035e-04 -4.162589e-04 -4.321334e-04
## ASV1502      3.904856e-05  3.913335e-05  3.907309e-05  3.884937e-05
## ASV0195     -6.526023e-05 -6.908367e-05 -7.315241e-05 -7.748324e-05
## ASV1213      1.493187e-03  1.558599e-03  1.626612e-03  1.697306e-03
## ASV1648     -1.357055e-03 -1.420045e-03 -1.485879e-03 -1.554680e-03
## ASV6984     -1.263558e-03 -1.322150e-03 -1.383379e-03 -1.447359e-03
## ASV0396     -1.315583e-04 -1.348660e-04 -1.380860e-04 -1.411959e-04
## ASV4297      2.096262e-03  2.188391e-03  2.284232e-03  2.383907e-03
## ASV2622      2.760882e-03  2.883594e-03  3.011369e-03  3.144381e-03
## ASV3512      9.609080e-04  1.006925e-03  1.055157e-03  1.105712e-03
## ASV2411      1.699306e-03  1.778513e-03  1.861321e-03  1.947886e-03
## ASV2291     -9.041649e-04 -9.495599e-04 -9.973322e-04 -1.047614e-03
## ASV0807      1.963061e-03  2.055037e-03  2.151229e-03  2.251819e-03
## ASV1292      6.471205e-04  6.755173e-04  7.050466e-04  7.357433e-04
## ASV1035      1.857278e-03  1.939138e-03  2.024303e-03  2.112881e-03
## ASV0070     -6.311439e-05 -6.496633e-05 -6.680569e-05 -6.862359e-05
## ASV0255      1.747047e-04  1.819078e-04  1.893478e-04  1.970262e-04
## ASV0057     -6.854293e-04 -7.150741e-04 -7.458650e-04 -7.778343e-04
## ASV0077     -1.158167e-04 -1.202803e-04 -1.248653e-04 -1.295702e-04
## ASV0625      1.342231e-03  1.401133e-03  1.462388e-03  1.526070e-03
## ASV2464      8.973501e-03  9.367790e-03  9.777881e-03  1.020427e-02
## ASV1315      2.675984e-03  2.798905e-03  2.927296e-03  3.061388e-03
## ASV2673      2.298580e-03  2.406942e-03  2.520359e-03  2.639062e-03
## ASV2161      9.871082e-04  1.033444e-03  1.081927e-03  1.132657e-03
## ASV0337     -5.280395e-04 -5.523414e-04 -5.777254e-04 -6.042366e-04
## ASV7680     -3.293201e-03 -3.446010e-03 -3.605712e-03 -3.772599e-03
## ASV0611      1.725425e-03  1.805536e-03  1.889271e-03  1.976787e-03
## ASV3118     -2.051725e-03 -2.148377e-03 -2.249514e-03 -2.355338e-03
## ASV1284      1.314358e-03  1.375112e-03  1.438503e-03  1.504623e-03
## ASV0889      1.245410e-03  1.300928e-03  1.358759e-03  1.418986e-03
## ASV4649     -6.979209e-04 -7.299763e-04 -7.634469e-04 -7.983899e-04
## ASV1108     -1.587035e-03 -1.662707e-03 -1.741978e-03 -1.825017e-03
## ASV0738      3.699631e-04  3.914209e-04  4.142327e-04  4.384897e-04
## ASV0473     -1.511971e-04 -1.592212e-04 -1.677011e-04 -1.766647e-04
## ASV0598     -9.280233e-04 -9.687428e-04 -1.011098e-03 -1.055142e-03
## ASV0429      1.330402e-03  1.389874e-03  1.451822e-03  1.516333e-03
## ASV1549      1.746696e-03  1.829390e-03  1.915971e-03  2.006618e-03
## ASV1203      1.457194e-03  1.522380e-03  1.590288e-03  1.661014e-03
## ASV4532      1.775368e-05  1.765313e-05  1.747085e-05  1.719736e-05
## ASV0274     -2.209053e-04 -2.293015e-04 -2.379231e-04 -2.467681e-04
## ASV0163     -1.217996e-03 -1.271313e-03 -1.326755e-03 -1.384389e-03
## ASV1298      4.986707e-04  5.201788e-04  5.425177e-04  5.657116e-04
## ASV9424     -2.841928e-03 -2.974356e-03 -3.112817e-03 -3.257571e-03
## ASV0412      2.436679e-03  2.545936e-03  2.659781e-03  2.778379e-03
## ASV0284      6.027949e-04  6.281709e-04  6.544582e-04  6.816752e-04
## ASV0620     -6.618238e-04 -6.947617e-04 -7.293847e-04 -7.657815e-04
## ASV0153     -1.972021e-03 -2.064999e-03 -2.162313e-03 -2.264162e-03
## ASV0498      7.572971e-04  7.934730e-04  8.313589e-04  8.710321e-04
## ASV0097      5.098821e-04  5.338440e-04  5.589186e-04  5.851564e-04
## ASV0104     -3.372464e-03 -3.525376e-03 -3.684884e-03 -3.851244e-03
## ASV1282      8.897656e-04  9.305125e-04  9.730229e-04  1.017362e-03
## ASV3883     -1.009959e-03 -1.058198e-03 -1.108730e-03 -1.161663e-03
## ASV0801      6.457097e-04  6.766081e-04  7.089808e-04  7.428970e-04
## ASV1611     -2.321007e-03 -2.429283e-03 -2.542500e-03 -2.660873e-03
## ASV0227     -4.961326e-04 -5.204617e-04 -5.460070e-04 -5.728305e-04
## ASV0833      6.681564e-04  6.991796e-04  7.316045e-04  7.654906e-04
## ASV0718      3.265851e-03  3.416024e-03  3.572856e-03  3.736619e-03
## ASV1139      4.417915e-04  4.593569e-04  4.774469e-04  4.960602e-04
## ASV0766     -5.654831e-04 -5.925210e-04 -6.208516e-04 -6.505363e-04
## ASV2091      3.375986e-03  3.523474e-03  3.676824e-03  3.836220e-03
## ASV1238     -1.188623e-03 -1.237724e-03 -1.288592e-03 -1.341276e-03
## ASV9193     -4.533825e-04 -4.804982e-04 -5.093064e-04 -5.399103e-04
## ASV0290      6.082449e-05  6.249268e-05  6.413757e-05  6.575028e-05
## ASV0231      1.066287e-03  1.114203e-03  1.164140e-03  1.216170e-03
## ASV0185      4.105309e-04  4.322370e-04  4.551583e-04  4.793666e-04
## ASV2330      9.856282e-04  1.028173e-03  1.072350e-03  1.118205e-03
## ASV3119     -5.584351e-04 -5.865529e-04 -6.161388e-04 -6.472726e-04
## ASV2368     -1.449200e-03 -1.517900e-03 -1.589840e-03 -1.665169e-03
## ASV0122     -4.754351e-04 -4.964290e-04 -5.182792e-04 -5.410149e-04
## ASV1044      1.556786e-03  1.630870e-03  1.708468e-03  1.789747e-03
## ASV0160     -7.964431e-04 -8.306097e-04 -8.660767e-04 -9.028797e-04
## ASV0326      2.291663e-04  2.396179e-04  2.505249e-04  2.619052e-04
## ASV1388      4.008873e-03  4.190230e-03  4.379359e-03  4.576557e-03
## ASV0792      2.427622e-03  2.535839e-03  2.648540e-03  2.765880e-03
## ASV0036     -6.385683e-04 -6.685527e-04 -6.999241e-04 -7.327444e-04
## ASV2125      2.219952e-03  2.320049e-03  2.424403e-03  2.533173e-03
## ASV1075      1.059825e-04  1.110594e-04  1.163822e-04  1.219632e-04
## ASV0390      1.200885e-03  1.258587e-03  1.319077e-03  1.382492e-03
## ASV3790     -1.822658e-03 -1.906409e-03 -1.993875e-03 -2.085210e-03
## ASV1535     -3.383569e-04 -3.565318e-04 -3.757359e-04 -3.960298e-04
## ASV0263      1.652240e-03  1.727405e-03  1.805821e-03  1.887614e-03
## ASV0675      3.185481e-03  3.334501e-03  3.490351e-03  3.653330e-03
## ASV3348      3.383955e-04  3.548814e-04  3.721859e-04  3.903507e-04
## ASV0058     -1.064076e-03 -1.111388e-03 -1.160658e-03 -1.211955e-03
## ASV4142      1.277200e-03  1.334174e-03  1.393517e-03  1.455312e-03
## ASV0059     -8.799490e-04 -9.188171e-04 -9.592699e-04 -1.001361e-03
## ASV0013     -1.215003e-03 -1.270343e-03 -1.328094e-03 -1.388349e-03
## ASV0033     -6.080440e-04 -6.366467e-04 -6.665771e-04 -6.978950e-04
## ASV4354     -8.133544e-04 -8.507216e-04 -8.897460e-04 -9.304963e-04
## ASV0022     -4.805231e-04 -5.031850e-04 -5.269042e-04 -5.517290e-04
## ASV0134     -5.214352e-04 -5.464170e-04 -5.726012e-04 -6.000458e-04
## ASV0415      5.409995e-05  5.843074e-05  6.310836e-05  6.815919e-05
## ASV10103    -2.880025e-03 -3.014195e-03 -3.154467e-03 -3.301104e-03
## ASV1613      2.205971e-03  2.303906e-03  2.405862e-03  2.511975e-03
## ASV0135     -3.582686e-04 -3.734400e-04 -3.891627e-04 -4.054482e-04
## ASV0469     -2.789658e-03 -2.914092e-03 -3.043705e-03 -3.178680e-03
## ASV0471      2.047421e-03  2.142405e-03  2.241653e-03  2.345342e-03
## ASV0451     -3.063798e-04 -3.223739e-04 -3.392546e-04 -3.570747e-04
## ASV0747      7.192595e-04  7.532537e-04  7.888317e-04  8.260644e-04
## ASV1314     -9.007683e-04 -9.438394e-04 -9.889739e-04 -1.036271e-03
## ASV0425     -3.992203e-03 -4.166398e-03 -4.347507e-03 -4.535746e-03
## ASV0559     -1.133391e-03 -1.183928e-03 -1.236578e-03 -1.291419e-03
## ASV0148     -6.331865e-04 -6.599675e-04 -6.877291e-04 -7.164936e-04
## ASV0129     -1.897248e-04 -1.952488e-04 -2.007387e-04 -2.061697e-04
## ASV1072      4.450106e-04  4.636094e-04  4.828752e-04  5.028229e-04
## ASV2390      1.512788e-03  1.578218e-03  1.646168e-03  1.716710e-03
## ASV0548      1.338851e-03  1.399881e-03  1.463575e-03  1.530040e-03
## ASV0168     -8.990812e-04 -9.391066e-04 -9.807933e-04 -1.024200e-03
## ASV0066     -7.399518e-04 -7.735586e-04 -8.086172e-04 -8.451834e-04
## ASV0468     -4.789220e-04 -5.009275e-04 -5.239076e-04 -5.479023e-04
## ASV0172     -2.228178e-04 -2.315831e-04 -2.406082e-04 -2.498929e-04
## ASV0236     -4.104787e-04 -4.248086e-04 -4.393812e-04 -4.541740e-04
## ASV0250      5.011243e-04  5.284068e-04  5.572701e-04  5.878103e-04
## ASV0338      4.724822e-04  4.962121e-04  5.211624e-04  5.473963e-04
## ASV0450     -4.150103e-05 -4.397119e-05 -4.660337e-05 -4.940903e-05
## ASV0377      1.023626e-03  1.070145e-03  1.118675e-03  1.169294e-03
## ASV1022      1.328293e-04  1.389914e-04  1.454326e-04  1.521650e-04
## ASV6174     -1.220762e-04 -1.281549e-04 -1.345458e-04 -1.412655e-04
## ASV0786      8.980405e-05  9.270636e-05  9.562321e-05  9.854476e-05
## ASV0053     -9.468617e-04 -9.905111e-04 -1.036105e-03 -1.083724e-03
## ASV0697     -7.541000e-04 -7.874955e-04 -8.222641e-04 -8.584536e-04
## ASV0785      1.403818e-03  1.466892e-03  1.532643e-03  1.601174e-03
## ASV1967     -1.287651e-03 -1.345044e-03 -1.404818e-03 -1.467056e-03
## ASV0385      1.823747e-04  1.922228e-04  2.026234e-04  2.136070e-04
## ASV0295      5.525102e-05  5.893062e-05  6.287791e-05  6.711334e-05
## ASV0072     -9.055674e-04 -9.453686e-04 -9.867738e-04 -1.029835e-03
## ASV0157     -3.297042e-04 -3.431220e-04 -3.569722e-04 -3.712572e-04
## ASV0501      2.342970e-03  2.453710e-03  2.569574e-03  2.690784e-03
## ASV10729    -2.760588e-03 -2.888851e-03 -3.022919e-03 -3.163041e-03
## ASV1470      1.588215e-03  1.652288e-03  1.718450e-03  1.786724e-03
## ASV0050     -2.129302e-03 -2.225236e-03 -2.325254e-03 -2.429510e-03
## ASV0411     -3.866684e-04 -4.042105e-04 -4.225187e-04 -4.416245e-04
## ASV0549      6.849357e-04  7.169403e-04  7.504173e-04  7.854325e-04
## ASV0184      2.119200e-04  2.214956e-04  2.314808e-04  2.418914e-04
## ASV0705      5.511056e-04  5.764901e-04  6.030003e-04  6.306817e-04
## ASV1715      1.243486e-03  1.300393e-03  1.359799e-03  1.421807e-03
## ASV0603      1.973656e-04  2.067460e-04  2.165722e-04  2.268657e-04
## ASV0826      1.684017e-03  1.759313e-03  1.837760e-03  1.919470e-03
## ASV0034     -6.786580e-04 -7.088026e-04 -7.401869e-04 -7.728529e-04
## ASV0838      9.371011e-04  9.780649e-04  1.020637e-03  1.064864e-03
## ASV0614     -7.791348e-04 -8.145819e-04 -8.515666e-04 -8.901489e-04
## ASV0014     -1.221079e-03 -1.276441e-03 -1.334191e-03 -1.394422e-03
## ASV0585     -1.051763e-04 -1.103249e-04 -1.157389e-04 -1.214334e-04
## ASV0016     -1.280877e-03 -1.338971e-03 -1.399573e-03 -1.462781e-03
## ASV5394     -1.248418e-03 -1.305859e-03 -1.365848e-03 -1.428488e-03
## ASV0666      2.324668e-03  2.427593e-03  2.534723e-03  2.646196e-03
## ASV2085      5.108654e-04  5.287995e-04  5.470302e-04  5.655261e-04
## ASV0003     -8.886711e-04 -9.289187e-04 -9.708990e-04 -1.014679e-03
## ASV0346      2.258203e-04  2.376998e-04  2.502373e-04  2.634710e-04
## ASV0267     -1.128845e-04 -1.166988e-04 -1.205490e-04 -1.244235e-04
## ASV0353      7.308322e-04  7.665003e-04  8.039234e-04  8.431871e-04
## ASV2419      2.425956e-03  2.534579e-03  2.647755e-03  2.765649e-03
## ASV0447      1.019468e-03  1.067684e-03  1.118155e-03  1.170982e-03
## ASV0654      1.667413e-03  1.743861e-03  1.823676e-03  1.906995e-03
## ASV0151      1.413478e-04  1.488901e-04  1.568632e-04  1.652939e-04
## ASV0065     -6.729833e-04 -7.027447e-04 -7.337226e-04 -7.659584e-04
## ASV0527      1.799598e-03  1.881405e-03  1.966755e-03  2.055788e-03
## ASV4055     -4.222166e-04 -4.429017e-04 -4.646236e-04 -4.874361e-04
## ASV0166     -9.068049e-04 -9.448247e-04 -9.842204e-04 -1.025024e-03
## ASV0417     -6.818750e-04 -7.115007e-04 -7.422826e-04 -7.742540e-04
## ASV0078     -4.848378e-04 -5.058604e-04 -5.277038e-04 -5.503924e-04
## ASV0322     -5.700814e-04 -5.923595e-04 -6.153021e-04 -6.389121e-04
## ASV0156     -1.125370e-03 -1.175324e-03 -1.227353e-03 -1.281532e-03
## ASV0648     -3.475015e-03 -3.636679e-03 -3.805682e-03 -3.982342e-03
## ASV0407     -1.010288e-04 -1.059901e-04 -1.111939e-04 -1.166515e-04
## ASV2030     -4.659474e-04 -4.868495e-04 -5.086408e-04 -5.313560e-04
## ASV0300      2.990121e-04  3.137515e-04  3.292277e-04  3.454772e-04
## ASV1150     -2.562434e-05 -2.647685e-05 -2.733745e-05 -2.820387e-05
## ASV0958      8.808476e-04  9.228651e-04  9.668862e-04  1.013006e-03
## ASV0216     -9.979119e-04 -1.042484e-03 -1.088920e-03 -1.137287e-03
## ASV0446      1.493489e-03  1.563793e-03  1.637353e-03  1.714316e-03
## ASV0367     -1.117934e-03 -1.169556e-03 -1.223489e-03 -1.279831e-03
## ASV0200     -6.247440e-04 -6.530074e-04 -6.824870e-04 -7.132301e-04
## ASV0334     -3.756261e-04 -3.906392e-04 -4.061175e-04 -4.220631e-04
## ASV1311      4.118260e-04  4.298794e-04  4.486529e-04  4.681690e-04
## ASV0458      8.863547e-04  9.247228e-04  9.645721e-04  1.005944e-03
## ASV1371      9.520878e-05  9.976820e-05  1.045446e-04  1.095478e-04
## ASV0418      2.148426e-03  2.240751e-03  2.336612e-03  2.436109e-03
## ASV0004      2.091866e-04  2.183707e-04  2.279232e-04  2.378559e-04
## ASV1943      7.378774e-03  7.699712e-03  8.033298e-03  8.379919e-03
## ASV1495     -3.355668e-04 -3.541324e-04 -3.738049e-04 -3.946547e-04
## ASV0901     -1.389847e-03 -1.454698e-03 -1.522516e-03 -1.593429e-03
## ASV0628      6.380025e-04  6.657115e-04  6.944978e-04  7.243916e-04
## ASV0400      3.365119e-04  3.517731e-04  3.676874e-04  3.842790e-04
## ASV0116     -3.904360e-04 -4.085041e-04 -4.273860e-04 -4.471162e-04
## ASV0788      2.772296e-03  2.900656e-03  3.034788e-03  3.174935e-03
## ASV0117      2.448211e-04  2.566152e-04  2.689820e-04  2.819495e-04
## ASV3137     -7.657655e-06 -7.850421e-06 -8.035525e-06 -8.211001e-06
## ASV0001      2.517107e-04  2.626399e-04  2.739981e-04  2.857983e-04
## ASV1651      6.461407e-04  6.739308e-04  7.027854e-04  7.327342e-04
## ASV1692      2.316254e-03  2.424149e-03  2.536954e-03  2.654882e-03
## ASV0660      7.549260e-04  7.867369e-04  8.196835e-04  8.537864e-04
## ASV0508     -1.541780e-05 -1.657737e-05 -1.782771e-05 -1.917583e-05
## ASV1660     -6.732268e-04 -7.056763e-04 -7.396968e-04 -7.753638e-04
## ASV0233      4.913799e-04  5.137472e-04  5.370883e-04  5.614419e-04
## ASV1343     -1.562915e-03 -1.635681e-03 -1.711758e-03 -1.791292e-03
## ASV0209      7.117140e-04  7.429423e-04  7.754205e-04  8.091884e-04
## ASV0193     -9.507738e-04 -9.900154e-04 -1.030624e-03 -1.072626e-03
## ASV0357      1.835774e-04  1.928075e-04  2.025200e-04  2.127411e-04
## ASV0198      5.759458e-04  6.026000e-04  6.304456e-04  6.595317e-04
## ASV0007      2.632612e-04  2.746214e-04  2.864213e-04  2.986736e-04
## ASV1772     -3.844217e-04 -4.011734e-04 -4.185774e-04 -4.366514e-04
## ASV0009      2.458604e-04  2.564093e-04  2.673610e-04  2.787268e-04
## ASV0006     -3.166882e-05 -3.354163e-05 -3.553264e-05 -3.764949e-05
## ASV0011     -4.919215e-04 -5.147218e-04 -5.385487e-04 -5.634454e-04
## ASV0015      1.602403e-04  1.671413e-04  1.743061e-04  1.817416e-04
## ASV0017      1.740456e-04  1.815393e-04  1.893197e-04  1.973945e-04
## ASV0235     -6.145316e-04 -6.437081e-04 -6.742553e-04 -7.062353e-04
## ASV0382      2.578537e-04  2.707604e-04  2.843236e-04  2.985760e-04
## ASV2357      1.972861e-03  2.064222e-03  2.159697e-03  2.259460e-03
## ASV0567     -5.205707e-04 -5.441383e-04 -5.687241e-04 -5.943684e-04
## ASV0165      3.463250e-04  3.625241e-04  3.794654e-04  3.971812e-04
## ASV0005      4.180075e-04  4.367235e-04  4.562255e-04  4.765420e-04
## ASV0384     -2.207998e-05 -2.211090e-05 -2.205139e-05 -2.188923e-05
## ASV0002      7.172859e-05  7.497020e-05  7.835052e-05  8.187481e-05
## ASV3017      2.687721e-03  2.807021e-03  2.931236e-03  3.060533e-03
## ASV0091     -5.905365e-07 -5.560091e-07 -5.152277e-07 -4.676460e-07
## ASV0186     -1.097698e-03 -1.147962e-03 -1.200433e-03 -1.255199e-03
## ASV0370      3.245963e-04  3.398721e-04  3.558588e-04  3.725886e-04
## ASV0018      5.707064e-04  5.963296e-04  6.230356e-04  6.508644e-04
## ASV1377      8.651823e-03  9.038474e-03  9.441256e-03  9.860738e-03
## ASV0019      5.978163e-04  6.246779e-04  6.526766e-04  6.818546e-04
## ASV0023     -1.798565e-04 -1.885712e-04 -1.977095e-04 -2.072916e-04
## ASV2194      6.721752e-04  7.024994e-04  7.341314e-04  7.671233e-04
## ASV1155      1.296992e-03  1.356635e-03  1.418914e-03  1.483937e-03
## ASV0510     -9.647987e-04 -1.003244e-03 -1.042908e-03 -1.083806e-03
## ASV2371     -1.447543e-03 -1.510545e-03 -1.576020e-03 -1.644043e-03
## ASV0024     -2.425623e-04 -2.541624e-04 -2.663140e-04 -2.790427e-04
## ASV2452      1.669663e-03  1.742132e-03  1.817437e-03  1.895664e-03
## ASV2332     -1.940325e-03 -2.027673e-03 -2.118651e-03 -2.213376e-03
## ASV2591      1.328474e-03  1.394911e-03  1.464768e-03  1.538225e-03
## ASV0521      9.236245e-04  9.667534e-04  1.011851e-03  1.059002e-03
## ASV5542      8.074706e-04  8.452089e-04  8.846682e-04  9.259223e-04
## ASV0336     -2.911290e-04 -3.032044e-04 -3.157190e-04 -3.286852e-04
## ASV10102     1.696773e-03  1.776273e-03  1.859431e-03  1.946411e-03
## ASV16823    -2.414098e-03 -2.518845e-03 -2.627681e-03 -2.740725e-03
## ASV3104      1.332074e-02  1.389864e-02  1.449910e-02  1.512276e-02
## ASV0781      1.548139e-03  1.619506e-03  1.694055e-03  1.771918e-03
## ASV10899     9.831229e-04  1.032378e-03  1.084181e-03  1.138667e-03
## ASV11222    -4.215879e-03 -4.398770e-03 -4.588795e-03 -4.786165e-03
## ASV11327    -3.791458e-03 -3.955914e-03 -4.126784e-03 -4.304256e-03
## ASV12458    -4.214773e-03 -4.397566e-03 -4.587486e-03 -4.784741e-03
## ASV1636      3.433147e-04  3.598028e-04  3.770826e-04  3.951916e-04
## ASV1890     -2.725654e-03 -2.842623e-03 -2.964037e-03 -3.090014e-03
## ASV2898      3.245334e-03  3.390610e-03  3.541967e-03  3.699624e-03
## ASV8328      1.502308e-04  1.645465e-04  1.801638e-04  1.971946e-04
## ASV0709     -3.605468e-03 -3.768082e-03 -3.937619e-03 -4.114337e-03
## ASV0856      2.532792e-03  2.652559e-03  2.777934e-03  2.909173e-03
## ASV0909     -1.719306e-04 -1.727391e-04 -1.729532e-04 -1.724946e-04
## ASV0937     -2.103315e-03 -2.200034e-03 -2.301049e-03 -2.406540e-03
## ASV11390    -5.969388e-03 -6.228236e-03 -6.497172e-03 -6.776492e-03
## ASV11966     1.446947e-03  1.516819e-03  1.590087e-03  1.666916e-03
## ASV12990     9.603374e-04  1.004427e-03  1.050461e-03  1.098517e-03
## ASV14797     1.626533e-03  1.698838e-03  1.774126e-03  1.852498e-03
## ASV14904    -8.473492e-03 -8.840916e-03 -9.222661e-03 -9.619145e-03
## ASV15304     7.739806e-04  8.132279e-04  8.545411e-04  8.980329e-04
## ASV16696    -2.997096e-03 -3.127043e-03 -3.262053e-03 -3.402275e-03
## ASV1690      5.139166e-03  5.381638e-03  5.635378e-03  5.900888e-03
## ASV2029      3.668583e-03  3.833383e-03  4.005137e-03  4.184099e-03
## ASV2834      5.928128e-03  6.200546e-03  6.485019e-03  6.782038e-03
## ASV4003      3.588131e-03  3.761261e-03  3.942815e-03  4.133206e-03
## ASV4064      2.225928e-03  2.327215e-03  2.432895e-03  2.543140e-03
## ASV4294      1.275012e-03  1.339140e-03  1.406616e-03  1.477624e-03
## ASV4609      6.797223e-04  7.093506e-04  7.401648e-04  7.722048e-04
## ASV6283     -2.804120e-03 -2.925712e-03 -3.052044e-03 -3.183254e-03
## ASV6491     -3.998294e-03 -4.171644e-03 -4.351750e-03 -4.538808e-03
## ASV7453      1.835711e-03  1.924708e-03  2.018050e-03  2.115949e-03
## ASV7959      4.860760e-04  5.128589e-04  5.412241e-04  5.712706e-04
## ASV8219      4.120878e-02  4.299532e-02  4.485148e-02  4.677928e-02
## ASV8547     -3.585254e-03 -3.740666e-03 -3.902131e-03 -4.069828e-03
## ASV9319      1.570745e-03  1.644569e-03  1.721809e-03  1.802621e-03
## ASV9382     -6.915103e-03 -7.214835e-03 -7.526241e-03 -7.849663e-03
## ASV11516    -4.663014e-03 -4.865103e-03 -5.075061e-03 -5.293117e-03
## ASV14377    -3.384899e-03 -3.531576e-03 -3.683963e-03 -3.842225e-03
## ASV1867      2.878617e-03  3.012172e-03  3.151761e-03  3.297643e-03
## ASV1895      4.892252e-04  5.112770e-04  5.342454e-04  5.581595e-04
## ASV3168      1.571223e-03  1.640831e-03  1.713281e-03  1.788669e-03
## ASV4449      1.011956e-02  1.057784e-02  1.105584e-02  1.155430e-02
## ASV6596      1.953106e-03  2.048676e-03  2.149018e-03  2.254374e-03
## ASV7492     -4.417876e-04 -4.566709e-04 -4.717335e-04 -4.869419e-04
## ASV9854     -8.782383e-04 -9.153898e-04 -9.539046e-04 -9.938148e-04
## ASV6296      7.595823e-02  7.924914e-02  8.266810e-02  8.621885e-02
## ASV4201      8.500861e-04  8.955509e-04  9.436064e-04  9.944093e-04
## ASV0552      1.871855e-03  1.958829e-03  2.049737e-03  2.144746e-03
## ASV3671     -9.492386e-04 -9.904182e-04 -1.033218e-03 -1.077688e-03
## ASV3529     -4.637486e-04 -4.806160e-04 -4.978431e-04 -5.154126e-04
## ASV1060      7.215936e-04  7.552272e-04  7.903952e-04  8.271646e-04
## ASV0239     -7.490646e-04 -7.808357e-04 -8.137693e-04 -8.478910e-04
## ASV5711     -2.955154e-03 -3.086814e-03 -3.223941e-03 -3.366729e-03
## ASV4152     -4.818413e-03 -5.036007e-03 -5.262894e-03 -5.499422e-03
## ASV1461      2.209888e-03  2.306206e-03  2.406316e-03  2.510330e-03
## ASV2877      1.142687e-03  1.192383e-03  1.244023e-03  1.297664e-03
## ASV0012      1.591036e-04  1.664061e-04  1.740309e-04  1.819912e-04
## ASV9823      3.499696e-04  3.615930e-04  3.733814e-04  3.853175e-04
## ASV0008      1.699391e-04  1.776829e-04  1.857638e-04  1.941950e-04
## ASV7832     -3.018230e-03 -3.155847e-03 -3.299468e-03 -3.449329e-03
## ASV1915     -5.985722e-05 -6.124302e-05 -6.257632e-05 -6.384638e-05
## ASV0055      1.502917e-05  1.501590e-05  1.493619e-05  1.478120e-05
## ASV0032      3.188749e-04  3.330001e-04  3.477040e-04  3.630064e-04
## ASV2977     -4.206283e-03 -4.394510e-03 -4.590609e-03 -4.794861e-03
## ASV0466      3.117495e-03  3.251797e-03  3.391241e-03  3.535964e-03
## ASV3866      2.153123e-03  2.253038e-03  2.357467e-03  2.466604e-03
## ASV0040      5.699844e-04  5.962093e-04  6.235980e-04  6.521984e-04
## ASV0496     -2.180155e-04 -2.309216e-04 -2.446611e-04 -2.592914e-04
## ASV0052      7.260304e-04  7.590441e-04  7.934883e-04  8.294186e-04
## ASV3828     -4.462932e-03 -4.664484e-03 -4.874666e-03 -5.093806e-03
## ASV1930      1.404920e-03  1.468869e-03  1.535586e-03  1.605179e-03
## ASV2126      1.728830e-03  1.806656e-03  1.887784e-03  1.972336e-03
## ASV0793      1.973567e-03  2.064713e-03  2.159930e-03  2.259386e-03
## ASV0299     -1.571282e-04 -1.642783e-04 -1.717408e-04 -1.795283e-04
## ASV0208      1.414918e-03  1.481060e-03  1.550227e-03  1.622549e-03
## ASV0511     -8.011392e-04 -8.358999e-04 -8.720197e-04 -9.095391e-04
## ASV1123     -2.540894e-03 -2.649802e-03 -2.762837e-03 -2.880109e-03
## ASV0099     -7.668372e-05 -7.937942e-05 -8.212125e-05 -8.490478e-05
## ASV0752     -7.962585e-04 -8.348538e-04 -8.753427e-04 -9.178194e-04
## ASV0883      1.003976e-03  1.051091e-03  1.100377e-03  1.151930e-03
## ASV0683      2.094835e-03  2.193281e-03  2.296282e-03  2.404042e-03
## ASV4117     -5.108023e-03 -5.338250e-03 -5.578275e-03 -5.828466e-03
## ASV2172      4.103860e-04  4.282561e-04  4.468312e-04  4.661329e-04
## ASV0330     -5.940486e-04 -6.210924e-04 -6.493171e-04 -6.787703e-04
## ASV0728      3.133504e-03  3.276566e-03  3.425876e-03  3.581681e-03
## ASV0499      7.644421e-04  8.003897e-04  8.380054e-04  8.773645e-04
## ASV0120     -1.304331e-03 -1.363645e-03 -1.425526e-03 -1.490073e-03
## ASV1446      1.258954e-03  1.311049e-03  1.364925e-03  1.420607e-03
## ASV17171    -2.328224e-03 -2.434212e-03 -2.544812e-03 -2.660207e-03
## ASV0533      2.185101e-04  2.290892e-04  2.401858e-04  2.518254e-04
## ASV2495     -8.520641e-04 -8.938095e-04 -9.376486e-04 -9.836902e-04
## ASV5582      1.011711e-03  1.052336e-03  1.094239e-03  1.137430e-03
## ASV1488      9.051295e-04  9.507741e-04  9.987426e-04  1.049149e-03
## ASV0682      5.715201e-04  5.987650e-04  6.273074e-04  6.572085e-04
## ASV0068     -6.179463e-04 -6.463570e-04 -6.760232e-04 -7.069954e-04
## ASV1987     -2.323736e-03 -2.434474e-03 -2.550477e-03 -2.671995e-03
## ASV0035     -9.802046e-05 -1.039740e-04 -1.103262e-04 -1.171057e-04
## ASV7192     -1.729803e-03 -1.806043e-03 -1.885366e-03 -1.967870e-03
## ASV0873      6.288653e-04  6.359770e-04  6.415004e-04  6.452127e-04
## ASV4749     -1.809724e-05 -2.392900e-05 -3.047616e-05 -3.780905e-05
## ASV2174      1.634668e-03  1.701970e-03  1.771625e-03  1.843684e-03
## ASV1476     -1.077351e-03 -1.127224e-03 -1.179347e-03 -1.233815e-03
## ASV0740     -3.722022e-03 -3.895570e-03 -4.077029e-03 -4.266741e-03
## ASV0170     -4.793754e-04 -5.013898e-04 -5.243772e-04 -5.483772e-04
## ASV2466     -3.589823e-03 -3.753835e-03 -3.925036e-03 -4.103714e-03
## ASV1709      1.487177e-03  1.552437e-03  1.620320e-03  1.690912e-03
## ASV6170     -8.408830e-03 -8.782406e-03 -9.171611e-03 -9.577033e-03
## ASV3673      2.509235e-03  2.618997e-03  2.733215e-03  2.852048e-03
## ASV1745      3.729963e-04  3.845354e-04  3.961625e-04  4.078535e-04
## ASV0380     -1.956651e-03 -2.028280e-03 -2.101637e-03 -2.176688e-03
## ASV0426      1.288064e-04  1.380169e-04  1.479041e-04  1.585162e-04
## ASV0202      2.184058e-05  2.502380e-05  2.854250e-05  3.242721e-05
## ASV6350     -2.748252e-03 -2.864737e-03 -2.985665e-03 -3.111173e-03
## ASV0713     -1.175372e-03 -1.229659e-03 -1.286380e-03 -1.345637e-03
## ASV1822      1.034609e-04  1.100174e-04  1.170010e-04  1.244382e-04
## ASV4569      3.543772e-03  3.699272e-03  3.861096e-03  4.029466e-03
## ASV0030     -3.208519e-04 -3.358840e-04 -3.516017e-04 -3.680341e-04
## ASV0331      1.275092e-03  1.335423e-03  1.398580e-03  1.464692e-03
## ASV2981      3.632637e-03  3.801774e-03  3.978560e-03  4.163318e-03
## ASV0828     -6.377293e-04 -6.835620e-04 -7.328127e-04 -7.857320e-04
## ASV2440      3.166093e-03  3.313169e-03  3.466888e-03  3.627532e-03
## ASV3006     -1.642617e-02 -1.706374e-02 -1.772074e-02 -1.839739e-02
## ASV3875      1.527156e-01  1.586425e-01  1.647499e-01  1.710400e-01
## ASV4511      1.786983e-03  1.870840e-03  1.958575e-03  2.050360e-03
## ASV4700     -6.039328e-03 -6.273688e-03 -6.515184e-03 -6.763899e-03
## ASV5804     -1.418166e-01 -1.473193e-01 -1.529895e-01 -1.588291e-01
## ASV6826      2.574370e-03  2.696394e-03  2.824163e-03  2.957944e-03
## ASV7280      2.406230e-03  2.522268e-03  2.643862e-03  2.771266e-03
## ASV7535     -6.038282e-03 -6.272568e-03 -6.513985e-03 -6.762617e-03
## ASV0651     -1.260102e-03 -1.315004e-03 -1.372054e-03 -1.431312e-03
## ASV0913      2.914262e-03  3.050954e-03  3.193966e-03  3.343583e-03
## ASV10832    -6.442743e-03 -6.692694e-03 -6.950252e-03 -7.215504e-03
## ASV1117     -6.538247e-03 -6.824937e-03 -7.123242e-03 -7.433560e-03
## ASV11329     1.048956e-03  1.104394e-03  1.162892e-03  1.224623e-03
## ASV13209     2.083031e-04  2.271088e-04  2.474240e-04  2.693514e-04
## ASV1345      1.568354e-03  1.643792e-03  1.722761e-03  1.805407e-03
## ASV1719     -9.072204e-03 -9.424131e-03 -9.786767e-03 -1.016024e-02
## ASV1886      1.755557e-03  1.833710e-03  1.915155e-03  2.000019e-03
## ASV2158     -4.113798e-05 -3.282802e-05 -2.342528e-05 -1.284460e-05
## ASV2189      2.970194e-03  3.105021e-03  3.245698e-03  3.392456e-03
## ASV2257      3.071829e-03  3.209795e-03  3.353690e-03  3.503752e-03
## ASV2283      7.027034e-03  7.299549e-03  7.580349e-03  7.869531e-03
## ASV2328      4.328916e-03  4.496776e-03  4.669738e-03  4.847862e-03
## ASV2434     -4.204347e-03 -4.385119e-03 -4.573010e-03 -4.768259e-03
## ASV2648      7.900812e-03  8.207087e-03  8.522663e-03  8.847649e-03
## ASV2698      8.132394e-03  8.507981e-03  8.900473e-03  9.310599e-03
## ASV2775      2.489713e-03  2.596094e-03  2.706529e-03  2.821133e-03
## ASV3171      3.808076e-03  3.955654e-03  4.107710e-03  4.264297e-03
## ASV3227      3.828820e-03  3.990793e-03  4.158788e-03  4.332962e-03
## ASV3397      1.867987e-03  1.956860e-03  2.049812e-03  2.147009e-03
## ASV3444      5.491611e-03  5.724911e-03  5.967165e-03  6.218659e-03
## ASV3556      1.583711e-02  1.645066e-02  1.708282e-02  1.773379e-02
## ASV3606     -3.722207e-02 -3.866394e-02 -4.014952e-02 -4.167931e-02
## ASV4190      5.206231e-03  5.444102e-03  5.692455e-03  5.951723e-03
## ASV4197      3.243814e-03  3.380980e-03  3.523281e-03  3.670859e-03
## ASV4722      4.964671e-03  5.186084e-03  5.416773e-03  5.657080e-03
## ASV4765      2.647185e-03  2.770810e-03  2.899917e-03  3.034714e-03
## ASV4809      9.356401e-03  9.718732e-03  1.009204e-02  1.047644e-02
## ASV4846      4.515399e-03  4.722999e-03  4.939756e-03  5.166036e-03
## ASV4903     -1.661175e-04 -1.628465e-04 -1.586318e-04 -1.533864e-04
## ASV4944     -3.831906e-03 -3.980288e-03 -4.133165e-03 -4.290586e-03
## ASV5151      2.960209e-04  2.551782e-04  2.082853e-04  1.547998e-04
## ASV5413     -8.429138e-03 -8.755517e-03 -9.091781e-03 -9.438040e-03
## ASV5537     -9.055124e-03 -9.405702e-03 -9.766894e-03 -1.013882e-02
## ASV5688      7.610716e-03  7.905338e-03  8.208878e-03  8.521437e-03
## ASV5752      2.338239e-03  2.449819e-03  2.566564e-03  2.688685e-03
## ASV6122     -9.748964e-03 -1.012634e-02 -1.051513e-02 -1.091548e-02
## ASV6135      5.117737e-03  5.315818e-03  5.519891e-03  5.730025e-03
## ASV6188     -3.107147e-02 -3.227394e-02 -3.351279e-02 -3.478841e-02
## ASV6216      7.173433e-03  7.482199e-03  7.803020e-03  8.136278e-03
## ASV6242      5.116013e-03  5.313956e-03  5.517881e-03  5.727858e-03
## ASV6383      3.198698e-02  3.322444e-02  3.449929e-02  3.581196e-02
## ASV6781      7.118398e-03  7.393751e-03  7.677424e-03  7.969508e-03
## ASV6799     -1.351722e-02 -1.404003e-02 -1.457863e-02 -1.513320e-02
## ASV7374     -2.868179e-03 -2.979101e-03 -3.093371e-03 -3.211029e-03
## ASV7539     -3.826392e-03 -3.974354e-03 -4.126782e-03 -4.283727e-03
## ASV8591     -9.737845e-03 -1.011435e-02 -1.050222e-02 -1.090158e-02
## ASV8637      4.274744e-02  4.440005e-02  4.610252e-02  4.785541e-02
## ASV12796    -5.640972e-03 -5.859027e-03 -6.083659e-03 -6.314940e-03
## ASV1934      3.017640e-03  3.156410e-03  3.301348e-03  3.452713e-03
## ASV22549     3.134651e-04  3.350412e-04  3.581059e-04  3.827538e-04
## ASV29857    -2.187959e-03 -2.272530e-03 -2.359651e-03 -2.449351e-03
## ASV3215      3.221805e-03  3.373498e-03  3.532268e-03  3.698439e-03
## ASV3236     -5.639695e-03 -5.857656e-03 -6.082188e-03 -6.313364e-03
## ASV3954     -5.639048e-03 -5.856959e-03 -6.081438e-03 -6.312557e-03
## ASV4850      3.779942e-03  3.925994e-03  4.076448e-03  4.231351e-03
## ASV5225      3.649930e-02  3.790943e-02  3.936204e-02  4.085760e-02
## ASV5532     -1.949432e-03 -2.024739e-03 -2.102313e-03 -2.182181e-03
## ASV7258      1.673136e-03  1.764212e-03  1.860493e-03  1.962283e-03
## ASV9474     -5.494739e-04 -5.618132e-04 -5.737252e-04 -5.851290e-04
## ASV11857    -7.324500e-03 -7.607438e-03 -7.898900e-03 -8.198977e-03
## ASV1202     -4.651156e-03 -4.830805e-03 -5.015864e-03 -5.206393e-03
## ASV14742     1.362950e-03  1.432747e-03  1.506234e-03  1.583608e-03
## ASV16652     1.037737e-03  1.088094e-03  1.140822e-03  1.196018e-03
## ASV2019      3.525018e-03  3.677516e-03  3.836030e-03  4.000755e-03
## ASV2410     -7.901919e-03 -8.261408e-03 -8.636684e-03 -9.028404e-03
## ASV2718      1.973957e-03  2.067391e-03  2.165173e-03  2.267496e-03
## ASV2738      5.776402e-03  6.024577e-03  6.282326e-03  6.549933e-03
## ASV2876      3.381544e-03  3.512123e-03  3.646632e-03  3.785114e-03
## ASV3177      4.531073e-03  4.706022e-03  4.886234e-03  5.071768e-03
## ASV4367      5.598664e-03  5.814809e-03  6.037455e-03  6.266673e-03
## ASV4635      1.862658e-03  1.958104e-03  2.058493e-03  2.164069e-03
## ASV4896      1.402201e-03  1.481856e-03  1.566284e-03  1.655777e-03
## ASV4907      1.569971e-03  1.649033e-03  1.732156e-03  1.819548e-03
## ASV5230     -4.358574e-03 -4.526874e-03 -4.700240e-03 -4.878729e-03
## ASV6509     -4.648742e-03 -4.828226e-03 -5.013111e-03 -5.203457e-03
## ASV7376     -3.325746e-03 -3.454135e-03 -3.586387e-03 -3.722545e-03
## ASV8163     -4.955368e-03 -5.146647e-03 -5.343679e-03 -5.546528e-03
## ASV8195     -4.356576e-03 -4.524722e-03 -4.697924e-03 -4.876238e-03
## ASV8923      1.438019e-03  1.509529e-03  1.584613e-03  1.663444e-03
## ASV9666     -2.250813e-03 -2.323117e-03 -2.396257e-03 -2.470112e-03
## ASV1482      2.400837e-03  2.514135e-03  2.632686e-03  2.756721e-03
## ASV2726      2.209436e-03  2.314115e-03  2.423670e-03  2.538314e-03
## ASV3281     -1.815169e-02 -1.885227e-02 -1.957392e-02 -2.031688e-02
## ASV4235     -1.814961e-02 -1.885003e-02 -1.957151e-02 -2.031429e-02
## ASV4808      3.807047e-03  3.971507e-03  4.142479e-03  4.320185e-03
## ASV4861     -9.304689e-03 -9.703265e-03 -1.011743e-02 -1.054771e-02
## ASV5276      5.429908e-03  5.663852e-03  5.906965e-03  6.159539e-03
## ASV5837      1.784804e-03  1.868045e-03  1.955113e-03  2.046180e-03
## ASV7098      2.562113e-03  2.680541e-03  2.804317e-03  2.933674e-03
## ASV8451     -3.088301e-03 -3.207404e-03 -3.330082e-03 -3.456371e-03
## ASV8694     -1.813749e-02 -1.883690e-02 -1.955729e-02 -2.029889e-02
## ASV0905     -8.298846e-04 -8.693946e-04 -9.106850e-04 -9.538205e-04
## ASV2900      4.248464e-03  4.423325e-03  4.604413e-03  4.791885e-03
## ASV3963     -4.303310e-03 -4.476800e-03 -4.656184e-03 -4.841593e-03
## ASV0041     -7.738967e-04 -8.102993e-04 -8.483796e-04 -8.882108e-04
## ASV1865      2.296527e-03  2.407797e-03  2.524444e-03  2.646719e-03
## ASV1140      1.286878e-03  1.347961e-03  1.411860e-03  1.478695e-03
## ASV1179      1.325566e-03  1.386407e-03  1.449925e-03  1.516228e-03
## ASV0279      2.011580e-03  2.101701e-03  2.195643e-03  2.293551e-03
## ASV0043     -3.588903e-04 -3.771104e-04 -3.962981e-04 -4.165079e-04
## ASV2097     -1.193970e-03 -1.244975e-03 -1.297973e-03 -1.353033e-03
## ASV0309     -2.368980e-04 -2.472614e-04 -2.580425e-04 -2.692557e-04
## ASV0607      3.158588e-03  3.304665e-03  3.457293e-03  3.616750e-03
## ASV0025     -8.792557e-04 -9.202156e-04 -9.630315e-04 -1.007782e-03
## ASV2284     -3.386002e-03 -3.526813e-03 -3.672736e-03 -3.823906e-03
## ASV0556      8.980807e-04  9.420554e-04  9.881963e-04  1.036608e-03
## ASV5040     -3.284845e-03 -3.495460e-03 -3.720052e-03 -3.959520e-03
## ASV2924     -1.082551e-02 -1.126424e-02 -1.171798e-02 -1.218705e-02
## ASV1331      2.795094e-03  2.922405e-03  3.055274e-03  3.193922e-03
## ASV0506     -1.201947e-03 -1.250435e-03 -1.300508e-03 -1.352187e-03
## ASV1514      4.234650e-03  4.427525e-03  4.628770e-03  4.838710e-03
## ASV2144      4.038280e-03  4.221794e-03  4.413279e-03  4.613053e-03
## ASV2265      2.657955e-03  2.779313e-03  2.905978e-03  3.038163e-03
## ASV5156      1.999529e-03  2.075277e-03  2.153107e-03  2.233015e-03
## ASV5534      6.016750e-04  6.221796e-04  6.430175e-04  6.641607e-04
## ASV5747     -7.901387e-04 -8.589770e-04 -9.334475e-04 -1.013964e-03
## ASV6657      2.052403e-03  2.140813e-03  2.232656e-03  2.328035e-03
## ASV0658     -1.519885e-03 -1.582475e-03 -1.647241e-03 -1.714225e-03
## ASV0716      2.746797e-03  2.866725e-03  2.991406e-03  3.120989e-03
## ASV1657      5.283079e-03  5.503471e-03  5.731776e-03  5.968176e-03
## ASV1885      4.428362e-03  4.600127e-03  4.776929e-03  4.958784e-03
## ASV2333      2.390154e-03  2.496954e-03  2.608228e-03  2.724138e-03
## ASV3375      1.849749e-03  1.928028e-03  2.009245e-03  2.093484e-03
## ASV4317      1.670093e-03  1.747076e-03  1.827527e-03  1.911598e-03
## ASV9599     -3.317965e-04 -3.606988e-04 -3.919653e-04 -4.257698e-04
## ASV0175     -2.591103e-03 -2.705305e-03 -2.824125e-03 -2.947712e-03
## ASV1032      1.089289e-03  1.134564e-03  1.181455e-03  1.229998e-03
## ASV1235      1.941703e-03  2.015424e-03  2.091126e-03  2.168792e-03
## ASV1262      2.672584e-03  2.792354e-03  2.917164e-03  3.047200e-03
## ASV1320      1.577341e-03  1.655466e-03  1.737530e-03  1.823734e-03
## ASV13797     1.543463e-03  1.611164e-03  1.681613e-03  1.754907e-03
## ASV1491      2.301632e-03  2.417210e-03  2.538644e-03  2.666221e-03
## ASV15014    -2.579996e-04 -2.804668e-04 -3.047709e-04 -3.310468e-04
## ASV1510      3.126897e-03  3.276006e-03  3.432114e-03  3.595531e-03
## ASV1551      1.051713e-02  1.099935e-02  1.150283e-02  1.202843e-02
## ASV1919      1.271137e-03  1.352264e-03  1.438772e-03  1.531003e-03
## ASV2114      1.913082e-03  1.994750e-03  2.079567e-03  2.167630e-03
## ASV21486    -2.215332e-04 -2.408177e-04 -2.616778e-04 -2.842294e-04
## ASV2448      1.984314e-03  2.071107e-03  2.161383e-03  2.255256e-03
## ASV2589      3.718751e-03  3.874727e-03  4.036419e-03  4.203972e-03
## ASV2608      2.518700e-03  2.630179e-03  2.746254e-03  2.867089e-03
## ASV2786      5.070415e-03  5.300651e-03  5.540974e-03  5.791804e-03
## ASV2827      1.779827e-03  1.857801e-03  1.938900e-03  2.023228e-03
## ASV2872      7.692162e-03  8.020978e-03  8.362231e-03  8.716256e-03
## ASV3125      1.501086e-03  1.564925e-03  1.631174e-03  1.699899e-03
## ASV3247      3.299579e-03  3.441461e-03  3.588817e-03  3.741810e-03
## ASV3451     -6.864665e-04 -7.462217e-04 -8.108594e-04 -8.807379e-04
## ASV3465      2.921293e-05  2.187435e-05  1.350692e-05  4.016406e-06
## ASV3809      4.436314e-03  4.625363e-03  4.821564e-03  5.025115e-03
## ASV4006      2.167265e-03  2.260730e-03  2.357815e-03  2.458627e-03
## ASV4046      3.183703e-03  3.320873e-03  3.463375e-03  3.611369e-03
## ASV4938      1.562148e-04  1.484951e-04  1.392529e-04  1.283420e-04
## ASV5435     -1.164721e-03 -1.266074e-03 -1.375703e-03 -1.494216e-03
## ASV5605      1.774067e-03  1.840995e-03  1.909689e-03  1.980130e-03
## ASV5635     -3.884857e-04 -4.222849e-04 -4.588434e-04 -4.983635e-04
## ASV5743      1.522832e-03  1.589525e-03  1.658908e-03  1.731071e-03
## ASV6627     -4.031885e-04 -4.382632e-04 -4.762009e-04 -5.172114e-04
## ASV6785     -4.487994e-04 -4.878367e-04 -5.300598e-04 -5.757019e-04
## ASV7368      1.909778e-03  1.997092e-03  2.088258e-03  2.183435e-03
## ASV9118      6.566253e-04  6.816054e-04  7.072869e-04  7.336708e-04
## ASV9135      1.201072e-03  1.243833e-03  1.287488e-03  1.332003e-03
## ASV9435      1.488547e-03  1.547074e-03  1.607374e-03  1.669457e-03
## ASV9671     -5.755194e-04 -6.255674e-04 -6.796985e-04 -7.382112e-04
## ASV0387     -2.654453e-03 -2.765759e-03 -2.881102e-03 -3.000579e-03
## ASV0454     -4.288274e-03 -4.472233e-03 -4.663226e-03 -4.861451e-03
## ASV0751     -1.205088e-03 -1.253218e-03 -1.302883e-03 -1.354099e-03
## ASV1081      2.636169e-03  2.755195e-03  2.879278e-03  3.008603e-03
## ASV1332      4.655754e-03  4.860687e-03  5.073893e-03  5.295639e-03
## ASV2659      5.203027e-03  5.439510e-03  5.686161e-03  5.943363e-03
## ASV2979      2.269106e-03  2.365286e-03  2.465036e-03  2.568447e-03
## ASV4184      3.193853e-03  3.320189e-03  3.450437e-03  3.584628e-03
## ASV6198      1.045012e-03  1.089441e-03  1.135577e-03  1.183476e-03
## ASV7454      1.113631e-03  1.160565e-03  1.209218e-03  1.259633e-03
## ASV8198      9.035051e-04  9.341033e-04  9.651684e-04  9.966535e-04
## ASV0855      2.837818e-03  2.966411e-03  3.100546e-03  3.240437e-03
## ASV10092     1.272527e-03  1.326694e-03  1.382916e-03  1.441254e-03
## ASV1532      2.558515e-03  2.678763e-03  2.804581e-03  2.936218e-03
## ASV2553      4.525632e-03  4.731213e-03  4.945700e-03  5.169442e-03
## ASV2741      6.267795e-03  6.563518e-03  6.872946e-03  7.196685e-03
## ASV4095      3.793493e-03  3.979263e-03  4.174094e-03  4.378405e-03
## ASV5295      1.269132e-03  1.320103e-03  1.372724e-03  1.427018e-03
## ASV5787     -2.366430e-04 -2.572118e-04 -2.794574e-04 -3.035023e-04
## ASV9455      1.730458e-03  1.805629e-03  1.883794e-03  1.965052e-03
## ASV10879     1.591393e-03  1.662092e-03  1.735745e-03  1.812462e-03
## ASV3997      2.111098e-03  2.212650e-03  2.319023e-03  2.430432e-03
## ASV6760      5.187398e-04  5.308993e-04  5.426593e-04  5.539354e-04
## ASV6990      1.616063e-03  1.684483e-03  1.755475e-03  1.829113e-03
## ASV9560      1.016545e-03  1.057479e-03  1.099779e-03  1.143471e-03
## ASV0220     -2.464714e-04 -2.575133e-04 -2.690207e-04 -2.810109e-04
## ASV2518      1.031866e-03  1.078822e-03  1.127817e-03  1.178930e-03
## ASV3615      2.586653e-03  2.701506e-03  2.821113e-03  2.945642e-03
## ASV0075     -1.010596e-05 -1.080186e-05 -1.154549e-05 -1.233984e-05
## ASV8070      9.687667e-05  9.696110e-05  9.669872e-05  9.604984e-05
## ASV1658      1.015966e-03  1.059173e-03  1.104014e-03  1.150533e-03
## ASV0773      1.880106e-03  1.961611e-03  2.046322e-03  2.134341e-03
## ASV0799      2.028824e-04  2.102586e-04  2.177848e-04  2.254513e-04
## ASV1839     -1.305500e-03 -1.362918e-03 -1.422638e-03 -1.484733e-03
## ASV0265      1.557198e-03  1.631132e-03  1.708540e-03  1.789580e-03
## ASV3741      5.402811e-04  5.623820e-04  5.852110e-04  6.087753e-04
## ASV0847      2.115317e-03  2.211783e-03  2.312457e-03  2.417506e-03
## ASV1026      2.761924e-03  2.885485e-03  3.014214e-03  3.148296e-03
## ASV1222     -7.002005e-04 -7.252520e-04 -7.508521e-04 -7.769831e-04
## ASV0729     -4.510782e-05 -4.723258e-05 -4.945685e-05 -5.178531e-05
## ASV0143     -6.894478e-04 -7.190804e-04 -7.498564e-04 -7.818098e-04
## ASV1328      3.585085e-04  3.774427e-04  3.974269e-04  4.185211e-04
## ASV9078     -8.231088e-04 -8.690563e-04 -9.176979e-04 -9.691926e-04
## ASV0027     -8.283661e-04 -8.668529e-04 -9.070738e-04 -9.491014e-04
## ASV0546     -9.369997e-04 -9.766002e-04 -1.017682e-03 -1.060288e-03
## ASV1136      2.304241e-03  2.408325e-03  2.516882e-03  2.630086e-03
## ASV3081      1.213577e-03  1.269049e-03  1.326980e-03  1.387473e-03
## ASV0531      3.788302e-04  3.989112e-04  4.201057e-04  4.424768e-04
## ASV2525      1.782906e-03  1.860435e-03  1.941033e-03  2.024796e-03
## ASV1083     -3.422364e-04 -3.547317e-04 -3.675265e-04 -3.806155e-04
## ASV0424     -2.594498e-04 -2.715348e-04 -2.841669e-04 -2.973691e-04
## ASV0644      1.661718e-04  1.806138e-04  1.962330e-04  2.131152e-04
## ASV6007     -1.663867e-04 -1.809213e-04 -1.966511e-04 -2.136652e-04
## ASV0564      8.671123e-04  9.083162e-04  9.514477e-04  9.965924e-04
## ASV1938      2.608645e-03  2.714747e-03  2.824406e-03  2.937676e-03
## ASV6516     -4.206050e-03 -4.398934e-03 -4.600344e-03 -4.810629e-03
## ASV0503     -1.631005e-03 -1.698235e-03 -1.767800e-03 -1.839747e-03
## ASV6913     -8.313939e-03 -8.684443e-03 -9.070567e-03 -9.472909e-03
## ASV0164     -1.046121e-03 -1.094777e-03 -1.145643e-03 -1.198813e-03
## ASV1576      2.943553e-03  3.076004e-03  3.214136e-03  3.358173e-03
## ASV1725      1.486660e-03  1.558657e-03  1.634112e-03  1.713185e-03
## ASV4501      7.455002e-04  7.733031e-04  8.017972e-04  8.309686e-04
## ASV10678    -3.870651e-03 -4.047151e-03 -4.231355e-03 -4.423570e-03
## ASV0944      6.215378e-04  6.513802e-04  6.826612e-04  7.154504e-04
## ASV2292      3.108547e-03  3.245854e-03  3.388768e-03  3.537481e-03
## ASV1090      1.254525e-03  1.310516e-03  1.368855e-03  1.429627e-03
## ASV9117     -8.314790e-04 -8.625097e-04 -8.943630e-04 -9.270352e-04
## ASV0285     -1.593433e-03 -1.678009e-03 -1.767242e-03 -1.861389e-03
## ASV0463     -8.672700e-04 -9.032486e-04 -9.404868e-04 -9.790083e-04
## ASV3199      1.096478e-03  1.141266e-03  1.187577e-03  1.235436e-03
## ASV0150     -1.903223e-04 -2.007313e-04 -2.117321e-04 -2.233579e-04
## ASV6583     -9.152544e-04 -9.521813e-04 -9.903936e-04 -1.029926e-03
## ASV0392      9.016869e-05  9.355044e-05  9.701635e-05  1.005646e-04
## ASV14007    -1.394337e-03 -1.455701e-03 -1.519539e-03 -1.585931e-03
## ASV0177     -6.539278e-04 -6.823527e-04 -7.118969e-04 -7.425948e-04
## ASV6448     -1.073888e-03 -1.130325e-03 -1.189834e-03 -1.252583e-03
## ASV5399     -6.419413e-03 -6.734543e-03 -7.065271e-03 -7.412358e-03
## ASV0277     -1.438684e-04 -1.499440e-04 -1.562334e-04 -1.627393e-04
## ASV2599      6.420667e-04  6.473303e-04  6.509295e-04  6.526649e-04
## ASV13465    -4.196891e-04 -4.326844e-04 -4.457708e-04 -4.589192e-04
## ASV2412      3.667742e-04  3.835930e-04  4.011548e-04  4.194900e-04
## ASV0423     -1.188313e-04 -1.220669e-04 -1.252459e-04 -1.283485e-04
## ASV5187      1.803995e-03  1.870782e-03  1.939275e-03  2.009455e-03
## ASV0701     -1.254385e-03 -1.312481e-03 -1.373191e-03 -1.436627e-03
## ASV4248      6.992920e-04  7.343606e-04  7.712130e-04  8.099384e-04
## ASV0519      1.191810e-03  1.248035e-03  1.306864e-03  1.368409e-03
## ASV0764      3.168689e-04  3.320703e-04  3.479915e-04  3.646646e-04
## ASV5385     -1.061094e-03 -1.110792e-03 -1.162782e-03 -1.217167e-03
## ASV3021     -1.723383e-03 -1.790555e-03 -1.859787e-03 -1.931104e-03
## ASV4119     -4.637909e-03 -4.846949e-03 -5.065019e-03 -5.292484e-03
## ASV2534     -2.228892e-04 -2.374077e-04 -2.529020e-04 -2.694353e-04
## ASV1061      1.214577e-03  1.275977e-03  1.340585e-03  1.408573e-03
## ASV0670     -3.164589e-04 -3.309770e-04 -3.461342e-04 -3.619557e-04
## ASV1384      1.406420e-03  1.476175e-03  1.549406e-03  1.626281e-03
## ASV1981      3.346053e-03  3.503329e-03  3.667862e-03  3.839974e-03
## ASV9632     -6.202572e-04 -6.388823e-04 -6.575905e-04 -6.763374e-04
## ASV4564      9.771861e-04  1.021959e-03  1.068691e-03  1.117458e-03
## ASV5289     -6.269925e-04 -6.582058e-04 -6.910244e-04 -7.255346e-04
## ASV0516      2.309821e-03  2.415091e-03  2.524932e-03  2.639521e-03
## ASV1463     -3.236928e-03 -3.384024e-03 -3.537499e-03 -3.697603e-03
## ASV0969      1.201690e-04  1.248682e-04  1.297000e-04  1.346628e-04
## ASV1113     -7.408343e-04 -7.748334e-04 -8.103355e-04 -8.474021e-04
## ASV1234     -9.375210e-04 -9.880750e-04 -1.041552e-03 -1.098132e-03
## ASV3814     -6.225908e-04 -6.647081e-04 -7.097419e-04 -7.578851e-04
## ASV1000      1.465427e-03  1.529986e-03  1.597151e-03  1.667006e-03
## ASV0079     -1.690241e-04 -1.782352e-04 -1.879778e-04 -1.982838e-04
## ASV0145      2.536354e-04  2.622223e-04  2.709544e-04  2.798219e-04
## ASV0457     -1.912975e-03 -1.998167e-03 -2.086894e-03 -2.179282e-03
## ASV1485      1.568624e-04  1.645814e-04  1.726895e-04  1.812070e-04
## ASV0535      6.086866e-04  6.402415e-04  6.734805e-04  7.084933e-04
## ASV0259     -1.071727e-03 -1.120111e-03 -1.170550e-03 -1.223119e-03
## ASV0570      3.397568e-04  3.569550e-04  3.750537e-04  3.941016e-04
## ASV0906      1.219747e-03  1.273087e-03  1.328552e-03  1.386210e-03
## ASV1748      1.085918e-03  1.117200e-03  1.148284e-03  1.179037e-03
## ASV5520     -1.687534e-03 -1.775060e-03 -1.867260e-03 -1.964382e-03
## ASV2288     -4.061640e-03 -4.247063e-03 -4.440595e-03 -4.642563e-03
## ASV1887     -8.899236e-04 -9.399931e-04 -9.929486e-04 -1.048949e-03
## ASV0374     -1.614974e-04 -1.673440e-04 -1.733236e-04 -1.794327e-04
## ASV0823      2.339799e-03  2.440897e-03  2.545960e-03  2.655112e-03
## ASV0717      1.776339e-04  1.858377e-04  1.944060e-04  2.033538e-04
## ASV0431     -4.860896e-04 -5.090722e-04 -5.331307e-04 -5.583141e-04
## ASV1030      5.577978e-03  5.841299e-03  6.116889e-03  6.405302e-03
## ASV1082     -7.235883e-04 -7.571940e-04 -7.923182e-04 -8.290257e-04
## ASV2684      1.396006e-04  1.503839e-04  1.619425e-04  1.743232e-04
## ASV0051      6.893674e-04  7.213046e-04  7.546845e-04  7.895695e-04
## ASV0513     -2.114774e-04 -2.203489e-04 -2.295356e-04 -2.390435e-04
## ASV0581      1.255451e-03  1.313165e-03  1.373430e-03  1.436347e-03
## ASV7282      4.332118e-04  4.579802e-04  4.842751e-04  5.121962e-04
## ASV3009     -1.073321e-03 -1.122527e-03 -1.173900e-03 -1.227527e-03
## ASV2106      1.334513e-03  1.406228e-03  1.481982e-03  1.562009e-03
## ASV1012      9.138359e-04  9.569238e-04  1.001991e-03  1.049122e-03
## ASV0921      9.288184e-04  9.737905e-04  1.020967e-03  1.070458e-03
## ASV0010     -5.390944e-04 -5.641604e-04 -5.903587e-04 -6.177370e-04
## ASV1178      2.475779e-04  2.595104e-04  2.720060e-04  2.850888e-04
## ASV2848     -1.426546e-03 -1.490009e-03 -1.556142e-03 -1.625049e-03
## ASV0586      3.605162e-03  3.775790e-03  3.954441e-03  4.141484e-03
## ASV4225     -4.964947e-03 -5.132160e-03 -5.302212e-03 -5.474928e-03
## ASV2156     -2.019680e-03 -2.114135e-03 -2.212924e-03 -2.316239e-03
## ASV9778     -1.446210e-03 -1.512975e-03 -1.582729e-03 -1.655596e-03
## ASV0493     -2.927476e-03 -3.058017e-03 -3.194028e-03 -3.335712e-03
## ASV3770     -4.018750e-04 -4.277256e-04 -4.552965e-04 -4.846984e-04
## ASV0470      2.063008e-03  2.158190e-03  2.257629e-03  2.361506e-03
## ASV0262     -9.075908e-04 -9.540612e-04 -1.002981e-03 -1.054479e-03
## ASV0998      5.406828e-04  5.660832e-04  5.926602e-04  6.204669e-04
## ASV7708     -2.527806e-04 -2.630984e-04 -2.737543e-04 -2.847514e-04
## ASV0453     -2.112913e-04 -2.209442e-04 -2.310324e-04 -2.415758e-04
## ASV0044      8.606398e-04  8.998525e-04  9.407714e-04  9.834637e-04
## ASV5490      4.807699e-04  5.005085e-04  5.208945e-04  5.419323e-04
## ASV2638     -2.767150e-04 -2.877216e-04 -2.991144e-04 -3.109073e-04
## ASV0829      2.966873e-03  3.101406e-03  3.241634e-03  3.387753e-03
## ASV0601      1.001276e-03  1.049100e-03  1.099202e-03  1.151689e-03
## ASV0234      7.825856e-05  8.234547e-05  8.665938e-05  9.121391e-05
## ASV0133      1.512023e-03  1.581814e-03  1.654724e-03  1.730883e-03
## ASV0323      5.027997e-04  5.271908e-04  5.527824e-04  5.796347e-04
## ASV0854     -3.422666e-04 -3.577899e-04 -3.739837e-04 -3.908741e-04
## ASV0110      9.546029e-04  9.989783e-04  1.045368e-03  1.093858e-03
## ASV0816     -9.518180e-05 -9.971637e-05 -1.044650e-04 -1.094376e-04
## ASV1031     -3.465931e-04 -3.612176e-04 -3.763926e-04 -3.921348e-04
## ASV0144     -4.434777e-04 -4.646463e-04 -4.868302e-04 -5.100786e-04
## ASV0020     -2.090926e-04 -2.195571e-04 -2.305664e-04 -2.421504e-04
## ASV0962     -5.639667e-04 -5.896128e-04 -6.163677e-04 -6.442740e-04
## ASV0794      1.077206e-03  1.130342e-03  1.186120e-03  1.244668e-03
## ASV7117     -9.812781e-04 -1.025196e-03 -1.070957e-03 -1.118631e-03
## ASV1008     -4.823177e-04 -5.055349e-04 -5.298750e-04 -5.553924e-04
## ASV0096      1.221621e-03  1.278338e-03  1.337622e-03  1.399582e-03
## ASV0128     -2.028872e-03 -2.125762e-03 -2.227283e-03 -2.333656e-03
## ASV5232      1.877550e-03  1.968811e-03  2.064530e-03  2.164922e-03
## ASV0031     -1.441868e-04 -1.509826e-04 -1.580930e-04 -1.655318e-04
## ASV1744     -1.963062e-03 -2.055826e-03 -2.152985e-03 -2.254751e-03
## ASV0289      5.501356e-04  5.755987e-04  6.022109e-04  6.300220e-04
## ASV7413     -3.420378e-04 -3.624444e-04 -3.841382e-04 -4.072007e-04
## ASV0822     -2.405097e-03 -2.511432e-03 -2.622115e-03 -2.737294e-03
## ASV8111     -3.976368e-03 -4.152649e-03 -4.336293e-03 -4.527579e-03
## ASV0687      5.274610e-04  5.526349e-04  5.789985e-04  6.066056e-04
## ASV0112     -1.929110e-04 -2.021975e-04 -2.119321e-04 -2.221362e-04
## ASV0987      6.530194e-04  6.844234e-04  7.173470e-04  7.518640e-04
## ASV5332     -3.683735e-04 -3.798235e-04 -3.914229e-04 -4.031623e-04
## ASV1129     -1.188193e-03 -1.243421e-03 -1.301163e-03 -1.361529e-03
## ASV1274     -3.275431e-04 -3.425790e-04 -3.582809e-04 -3.746764e-04
## ASV0119      7.918939e-04  8.285983e-04  8.669585e-04  9.070452e-04
## ASV0890     -4.320744e-05 -4.549369e-05 -4.791553e-05 -5.048251e-05
## ASV0848     -1.470374e-03 -1.538505e-03 -1.609712e-03 -1.684124e-03
## ASV5944     -6.430375e-03 -6.722122e-03 -7.026475e-03 -7.343924e-03
## ASV19741    -2.348696e-03 -2.455940e-03 -2.567882e-03 -2.684710e-03
## ASV0504     -2.938330e-03 -3.068585e-03 -3.204222e-03 -3.345432e-03
## ASV2146     -2.107180e-03 -2.198098e-03 -2.292594e-03 -2.390785e-03
## ASV0089     -5.008140e-04 -5.237619e-04 -5.477171e-04 -5.727195e-04
## ASV2301     -8.169955e-04 -8.552933e-04 -8.953550e-04 -9.372589e-04
## ASV2982     -1.354133e-02 -1.405383e-02 -1.458085e-02 -1.512248e-02
## ASV0891     -9.488440e-04 -9.924696e-04 -1.038031e-03 -1.085607e-03
## ASV0093      1.034337e-03  1.081474e-03  1.130669e-03  1.182003e-03
## ASV0042      3.641787e-04  3.810789e-04  3.987442e-04  4.172077e-04
## ASV0980      1.156158e-03  1.205849e-03  1.257427e-03  1.310943e-03
## ASV0069     -5.558469e-04 -5.815887e-04 -6.084864e-04 -6.365885e-04
## ASV1364     -4.233484e-04 -4.424259e-04 -4.623140e-04 -4.830430e-04
## ASV0524     -2.148177e-03 -2.249349e-03 -2.355229e-03 -2.466030e-03
## ASV0435      2.935892e-03  3.072926e-03  3.216226e-03  3.366069e-03
## ASV0517     -5.787414e-04 -6.056373e-04 -6.337531e-04 -6.631415e-04
## ASV3167     -4.290954e-03 -4.508614e-03 -4.737601e-03 -4.978507e-03
## ASV4280     -2.640386e-03 -2.762051e-03 -2.889150e-03 -3.021911e-03
## ASV1158      9.642546e-04  1.012693e-03  1.063564e-03  1.116981e-03
## ASV2214      8.720975e-04  9.105274e-04  9.505786e-04  9.923194e-04
## ASV0544     -1.448202e-03 -1.517161e-03 -1.589397e-03 -1.665062e-03
## ASV5326     -2.036460e-04 -2.135988e-04 -2.240497e-04 -2.350247e-04
## ASV3765     -1.116141e-03 -1.167308e-03 -1.220728e-03 -1.276493e-03
## ASV4646     -2.094426e-05 -2.670779e-05 -3.310673e-05 -4.019408e-05
## ASV0090      8.349736e-05  8.674626e-05  9.008571e-05  9.351468e-05
## ASV3680      1.810253e-03  1.887298e-03  1.967220e-03  2.050092e-03
## ASV0111      1.915784e-04  1.999690e-04  2.086945e-04  2.177655e-04
## ASV0768      2.824809e-04  2.962386e-04  3.106783e-04  3.258348e-04
## ASV4862     -1.466413e-04 -1.512514e-04 -1.558644e-04 -1.604612e-04
## ASV1742     -1.614542e-03 -1.686687e-03 -1.761875e-03 -1.840223e-03
## ASV3701     -5.801156e-04 -6.028031e-04 -6.261915e-04 -6.502886e-04
## ASV2386     -3.119751e-03 -3.266552e-03 -3.420126e-03 -3.580767e-03
## ASV0375     -2.177206e-03 -2.275037e-03 -2.377045e-03 -2.483391e-03
## ASV2796      7.383391e-04  7.694863e-04  8.018115e-04  8.353515e-04
## ASV1369      1.670419e-03  1.743388e-03  1.819373e-03  1.898494e-03
## ASV10272    -2.473247e-03 -2.586118e-03 -2.703904e-03 -2.826796e-03
## ASV10354    -3.682928e-03 -3.850980e-03 -4.026348e-03 -4.209317e-03
## ASV1067      1.202365e-03  1.256605e-03  1.313168e-03  1.372141e-03
## ASV1900      1.992561e-03  2.085514e-03  2.182711e-03  2.284339e-03
## ASV4079     -9.281347e-04 -9.744611e-04 -1.023144e-03 -1.074304e-03
## ASV4149      3.830225e-03  3.995419e-03  4.166984e-03  4.345101e-03
## ASV5140     -3.682581e-03 -3.850599e-03 -4.025930e-03 -4.208858e-03
## ASV10782     1.503296e-04  1.610993e-04  1.727137e-04  1.852424e-04
## ASV4273     -3.295194e-04 -3.411172e-04 -3.528873e-04 -3.648039e-04
## ASV8121      1.663058e-03  1.739797e-03  1.819977e-03  1.903746e-03
## ASV8438     -4.189508e-03 -4.380638e-03 -4.580085e-03 -4.788174e-03
## ASV9390     -4.188929e-03 -4.380005e-03 -4.579394e-03 -4.787418e-03
## ASV1340      3.399530e-03  3.558070e-03  3.723837e-03  3.897145e-03
## ASV2650     -7.766069e-03 -8.117295e-03 -8.483536e-03 -8.865356e-03
## ASV4674      2.073647e-03  2.167551e-03  2.265483e-03  2.367592e-03
## ASV10492     2.462533e-05  2.436888e-05  2.397198e-05  2.341698e-05
## ASV11430    -3.196344e-03 -3.342116e-03 -3.494227e-03 -3.652924e-03
## ASV12135    -3.195902e-03 -3.341633e-03 -3.493700e-03 -3.652348e-03
## ASV14970    -3.929865e-03 -4.109039e-03 -4.295999e-03 -4.491048e-03
## ASV1954      4.781307e-03  5.000350e-03  5.229024e-03  5.467715e-03
## ASV2613      3.016444e-03  3.153541e-03  3.296573e-03  3.445772e-03
## ASV2757      1.846174e-03  1.926072e-03  2.009082e-03  2.095296e-03
## ASV2909     -5.679945e-03 -5.948062e-03 -6.228711e-03 -6.522464e-03
## ASV2954     -2.119956e-04 -2.217396e-04 -2.319105e-04 -2.425250e-04
## ASV2969      1.448033e-03  1.515771e-03  1.586619e-03  1.660716e-03
## ASV3410      5.170246e-04  5.418282e-04  5.678322e-04  5.950958e-04
## ASV3575      9.680223e-04  1.011382e-03  1.056576e-03  1.103673e-03
## ASV4275      2.466859e-03  2.574937e-03  2.687329e-03  2.804173e-03
## ASV4652      5.445068e-04  5.703586e-04  5.974318e-04  6.257834e-04
## ASV4761      1.786166e-03  1.864086e-03  1.945076e-03  2.029227e-03
## ASV6003      1.350262e-03  1.415320e-03  1.483540e-03  1.555080e-03
## ASV6110     -9.018481e-03 -9.429780e-03 -9.858965e-03 -1.030673e-02
## ASV7427      1.556382e-03  1.625909e-03  1.698339e-03  1.773776e-03
## ASV8092     -2.957245e-03 -3.092101e-03 -3.232820e-03 -3.379630e-03
## ASV8169     -9.016413e-03 -9.427519e-03 -9.856493e-03 -1.030403e-02
## ASV9693      1.526908e-03  1.596088e-03  1.668236e-03  1.743464e-03
## ASV10913     1.036784e-03  1.085385e-03  1.136226e-03  1.189408e-03
## ASV1979      9.010079e-04  9.409513e-04  9.825241e-04  1.025780e-03
## ASV3772      1.860854e-03  1.943363e-03  2.029267e-03  2.118687e-03
## ASV0113     -2.540874e-04 -2.659726e-04 -2.784009e-04 -2.913956e-04
## ASV1800     -3.365179e-04 -3.523527e-04 -3.689119e-04 -3.862258e-04
## ASV2335     -6.892645e-03 -7.202827e-03 -7.526326e-03 -7.863669e-03
## ASV0692     -4.822699e-05 -5.064346e-05 -5.318873e-05 -5.587050e-05
## ASV1120      2.533777e-04  2.654381e-04  2.780727e-04  2.913087e-04
## ASV1434     -1.249011e-03 -1.307005e-03 -1.367624e-03 -1.430981e-03
## ASV0076     -5.845437e-04 -6.115694e-04 -6.398046e-04 -6.692996e-04
## ASV0361      2.092867e-03  2.190499e-03  2.292592e-03  2.399343e-03
## ASV2231     -6.910877e-04 -7.258169e-04 -7.623532e-04 -8.007942e-04
## ASV2018     -1.677179e-04 -1.754903e-04 -1.836152e-04 -1.921080e-04
## ASV1529      9.131150e-04  9.566373e-04  1.002232e-03  1.049998e-03
## ASV0841     -3.141084e-04 -3.284302e-04 -3.433767e-04 -3.589726e-04
## ASV2556     -5.785625e-03 -6.052427e-03 -6.331118e-03 -6.622191e-03
## ASV2777      1.860213e-03  1.938063e-03  2.018691e-03  2.102155e-03
## ASV0355      1.440057e-03  1.506275e-03  1.575434e-03  1.647656e-03
## ASV5169     -1.719376e-03 -1.797975e-03 -1.880011e-03 -1.965620e-03
## ASV3091      1.635594e-03  1.712656e-03  1.793311e-03  1.877721e-03
## ASV2435      6.537537e-04  6.834767e-04  7.144843e-04  7.468258e-04
## ASV6822     -3.542081e-03 -3.703678e-03 -3.872308e-03 -4.048244e-03
## ASV12605    -3.470456e-03 -3.631934e-03 -3.800741e-03 -3.977194e-03
## ASV0286     -8.296487e-04 -8.677650e-04 -9.075865e-04 -9.491870e-04
## ASV0074     -3.299992e-04 -3.454400e-04 -3.615875e-04 -3.784726e-04
## ASV2485     -1.480996e-04 -1.564749e-04 -1.653816e-04 -1.748579e-04
## ASV1233     -2.608027e-03 -2.729722e-03 -2.856990e-03 -2.990077e-03
## ASV0356     -6.836141e-04 -7.144571e-04 -7.466271e-04 -7.801769e-04
## ASV2918     -2.885201e-03 -3.016930e-03 -3.154426e-03 -3.297921e-03
## ASV1427     -3.698261e-04 -3.879889e-04 -4.070692e-04 -4.271155e-04
## ASV1409      6.452990e-04  6.760726e-04  7.083129e-04  7.420895e-04
## ASV0770      1.963337e-04  2.047832e-04  2.135537e-04  2.226537e-04
## ASV1403     -1.780235e-03 -1.861986e-03 -1.947354e-03 -2.036485e-03
## ASV0314     -6.113953e-04 -6.385869e-04 -6.668929e-04 -6.963500e-04
## ASV0187     -1.836304e-04 -1.923917e-04 -2.015637e-04 -2.111642e-04
## ASV0313     -8.722344e-04 -9.115846e-04 -9.526082e-04 -9.953670e-04
## ASV1087      2.022842e-03  2.116010e-03  2.213328e-03  2.314967e-03
## ASV1970     -3.066738e-04 -3.206548e-04 -3.352413e-04 -3.504565e-04
## ASV0754      2.231454e-03  2.334964e-03  2.443151e-03  2.556215e-03
## ASV3775     -5.352805e-04 -5.603982e-04 -5.866768e-04 -6.141682e-04
## ASV0132     -3.843546e-04 -4.021181e-04 -4.206781e-04 -4.400682e-04
## ASV2329      1.727666e-04  1.750817e-04  1.770510e-04  1.786285e-04
## ASV0561      5.562170e-04  5.802148e-04  6.051218e-04  6.309600e-04
## ASV0130     -1.162460e-03 -1.216330e-03 -1.272624e-03 -1.331443e-03
## ASV0226      1.459948e-03  1.526853e-03  1.596700e-03  1.669609e-03
## ASV12648    -2.035751e-03 -2.127408e-03 -2.223003e-03 -2.322693e-03
## ASV0204      1.405088e-03  1.469498e-03  1.536742e-03  1.606935e-03
## ASV0767     -6.954355e-04 -7.295048e-04 -7.652837e-04 -8.028613e-04
## ASV0335     -1.306276e-03 -1.365856e-03 -1.428027e-03 -1.492890e-03
## ASV5901     -2.813201e-04 -2.934777e-04 -3.061207e-04 -3.192660e-04
## ASV0596      9.283253e-06  1.113683e-05  1.320364e-05  1.550427e-05
## ASV9271      1.094777e-03  1.150390e-03  1.208882e-03  1.270404e-03
## ASV0904      8.562609e-04  8.968049e-04  9.392543e-04  9.836971e-04
## ASV15270    -5.796715e-04 -6.098184e-04 -6.415668e-04 -6.749992e-04
## ASV0990     -4.720148e-04 -4.941847e-04 -5.173815e-04 -5.416513e-04
## ASV0155     -9.737752e-04 -1.018606e-03 -1.065428e-03 -1.114323e-03
## ASV0086     -1.945205e-04 -2.035156e-04 -2.129141e-04 -2.227328e-04
## ASV2581     -9.063396e-05 -9.431671e-05 -9.811384e-05 -1.020250e-04
## ASV1579     -8.047658e-04 -8.430740e-04 -8.831991e-04 -9.252262e-04
## ASV7730     -6.091154e-05 -6.592591e-05 -7.130943e-05 -7.708348e-05
## ASV0897      1.218175e-04  1.277971e-04  1.340761e-04  1.406698e-04
## ASV1975      5.456583e-03  5.708507e-03  5.971722e-03  6.246704e-03
##                                                                    
## (Intercept)  2.031563e-02  2.124782e-02  2.222094e-02  2.323663e-02
## ASV1236      3.227449e-03  3.368852e-03  3.515894e-03  3.668750e-03
## ASV0421     -1.519706e-03 -1.585457e-03 -1.653756e-03 -1.724677e-03
## ASV0691     -3.052244e-03 -3.177170e-03 -3.306317e-03 -3.439752e-03
## ASV0899      1.923241e-03  2.012337e-03  2.105402e-03  2.202595e-03
## ASV1004      7.286357e-03  7.607457e-03  7.941532e-03  8.289006e-03
## ASV1041     -4.474270e-03 -4.673561e-03 -4.881070e-03 -5.097075e-03
## ASV1058      4.541614e-03  4.741993e-03  4.950509e-03  5.167429e-03
## ASV12542     1.697403e-03  1.770509e-03  1.846437e-03  1.925270e-03
## ASV1294      3.829004e-03  3.998945e-03  4.175869e-03  4.360015e-03
## ASV13113     1.402606e-03  1.469834e-03  1.540303e-03  1.614170e-03
## ASV1318      4.188479e-03  4.373825e-03  4.566730e-03  4.767447e-03
## ASV2269     -7.139716e-03 -7.458052e-03 -7.789479e-03 -8.134429e-03
## ASV2542      3.196038e-03  3.344485e-03  3.499645e-03  3.661805e-03
## ASV2660     -3.159335e-03 -3.298350e-03 -3.442945e-03 -3.593299e-03
## ASV2737      5.584940e-04  5.802051e-04  6.025611e-04  6.255656e-04
## ASV2840      3.939132e-03  4.109406e-03  4.286255e-03  4.469864e-03
## ASV3053      3.333784e-02  3.479639e-02  3.631312e-02  3.788985e-02
## ASV3077      1.172978e-03  1.224174e-03  1.277413e-03  1.332762e-03
## ASV3134      2.315555e-03  2.424678e-03  2.538891e-03  2.658429e-03
## ASV3140      2.791573e-03  2.919357e-03  3.052715e-03  3.191864e-03
## ASV3579      9.329232e-04  9.783071e-04  1.025938e-03  1.075928e-03
## ASV6119     -1.948461e-03 -2.035318e-03 -2.125745e-03 -2.219860e-03
## ASV7557     -3.963239e-03 -4.139879e-03 -4.323778e-03 -4.515173e-03
## ASV8422      8.524921e-04  8.882740e-04  9.253695e-04  9.638125e-04
## ASV1086     -2.011710e-04 -2.093930e-04 -2.179048e-04 -2.267136e-04
## ASV1310      1.681919e-03  1.756016e-03  1.833107e-03  1.913289e-03
## ASV15750    -2.866237e-04 -2.989596e-04 -3.117521e-04 -3.250105e-04
## ASV16905    -8.136181e-04 -8.498793e-04 -8.876303e-04 -9.269202e-04
## ASV2033      3.623004e-03  3.790050e-03  3.964542e-03  4.146789e-03
## ASV2089      1.489723e-03  1.556356e-03  1.625743e-03  1.697974e-03
## ASV2127      5.597172e-03  5.843615e-03  6.100012e-03  6.366685e-03
## ASV2725      4.458473e-03  4.651484e-03  4.851999e-03  5.060238e-03
## ASV2804     -1.684974e-03 -1.760065e-03 -1.838241e-03 -1.919603e-03
## ASV3075      3.775630e-03  3.943911e-03  4.119217e-03  4.301803e-03
## ASV3327      5.207694e-03  5.447242e-03  5.697439e-03  5.958725e-03
## ASV3342      4.279153e-03  4.474419e-03  4.678181e-03  4.890769e-03
## ASV3532     -4.876310e-03 -5.099623e-03 -5.332714e-03 -5.575970e-03
## ASV3600      2.186764e-03  2.285510e-03  2.388484e-03  2.495849e-03
## ASV4013      4.202212e-03  4.388906e-03  4.583297e-03  4.785651e-03
## ASV4136      4.584413e-03  4.783191e-03  4.989720e-03  5.204229e-03
## ASV4195      1.703027e-02  1.778908e-02  1.857904e-02  1.940118e-02
## ASV4407     -6.661043e-03 -6.957783e-03 -7.266703e-03 -7.588204e-03
## ASV4717      6.066245e-04  6.282443e-04  6.503374e-04  6.728901e-04
## ASV6794      2.555323e-03  2.661919e-03  2.772343e-03  2.886683e-03
## ASV8324     -3.412032e-03 -3.564026e-03 -3.722257e-03 -3.886932e-03
## ASV8981     -1.108824e-04 -1.148017e-04 -1.187781e-04 -1.228025e-04
## ASV9859      1.081636e-03  1.135790e-03  1.192770e-03  1.252733e-03
## ASV0936      2.837649e-04  2.984784e-04  3.139579e-04  3.302408e-04
## ASV12683    -9.213766e-05 -9.730480e-05 -1.027596e-04 -1.085162e-04
## ASV1293      2.134249e-03  2.227909e-03  2.325317e-03  2.426593e-03
## ASV13055    -1.095423e-04 -1.134744e-04 -1.174604e-04 -1.214898e-04
## ASV17063    -1.768407e-03 -1.847150e-03 -1.929122e-03 -2.014429e-03
## ASV2228      1.439587e-03  1.503677e-03  1.570395e-03  1.639826e-03
## ASV2769      1.490248e-04  1.563713e-04  1.640975e-04  1.722241e-04
## ASV2803      1.252146e-03  1.304282e-03  1.358279e-03  1.414179e-03
## ASV2896      1.208588e-03  1.263911e-03  1.321687e-03  1.382020e-03
## ASV3062      1.317406e-03  1.379904e-03  1.445362e-03  1.513918e-03
## ASV3107      2.423887e-03  2.535054e-03  2.651138e-03  2.772343e-03
## ASV3265      3.293560e-03  3.438122e-03  3.588481e-03  3.744822e-03
## ASV3666      9.691641e-06  9.883323e-06  1.007390e-05  1.026366e-05
## ASV4497      1.005433e-03  1.050038e-03  1.096490e-03  1.144854e-03
## ASV6914     -2.506393e-04 -2.630805e-04 -2.761381e-04 -2.898410e-04
## ASV0576     -4.180443e-03 -4.356649e-03 -4.539296e-03 -4.728537e-03
## ASV0673      3.183274e-03  3.328269e-03  3.479554e-03  3.637371e-03
## ASV0772      1.824164e-03  1.905516e-03  1.990268e-03  2.078543e-03
## ASV0862     -2.698446e-04 -2.785062e-04 -2.872426e-04 -2.960327e-04
## ASV0898      1.353185e-03  1.416685e-03  1.483098e-03  1.552550e-03
## ASV0910      1.662131e-03  1.738952e-03  1.819217e-03  1.903071e-03
## ASV0964     -1.680359e-03 -1.753214e-03 -1.828930e-03 -1.907595e-03
## ASV10059     1.192819e-03  1.249957e-03  1.309854e-03  1.372644e-03
## ASV10263    -2.695063e-03 -2.815176e-03 -2.940224e-03 -3.070372e-03
## ASV1088      2.669465e-03  2.792426e-03  2.920894e-03  3.055104e-03
## ASV1101      3.122267e-03  3.259949e-03  3.403201e-03  3.552204e-03
## ASV1183      9.607062e-04  1.004734e-03  1.050689e-03  1.098648e-03
## ASV11956     8.082436e-04  8.403928e-04  8.735656e-04  9.077748e-04
## ASV12774    -2.612987e-05 -2.887148e-05 -3.185627e-05 -3.510311e-05
## ASV1321      4.144077e-03  4.336074e-03  4.536726e-03  4.746402e-03
## ASV13793    -1.857267e-03 -1.940029e-03 -2.026191e-03 -2.115865e-03
## ASV14482     7.710265e-06  6.402685e-06  4.915906e-06  3.235196e-06
## ASV15483     6.944299e-04  7.263964e-04  7.597962e-04  7.946906e-04
## ASV2062      3.438861e-03  3.592716e-03  3.753012e-03  3.919980e-03
## ASV2132      3.021510e-03  3.160981e-03  3.306700e-03  3.458930e-03
## ASV2413      2.693223e-03  2.811332e-03  2.934183e-03  3.061928e-03
## ASV2490      8.288448e-03  8.642443e-03  9.009759e-03  9.390741e-03
## ASV2594      9.776723e-04  1.021526e-03  1.067252e-03  1.114924e-03
## ASV2822     -4.909284e-03 -5.128123e-03 -5.355958e-03 -5.593088e-03
## ASV2863      5.276173e-03  5.505726e-03  5.744291e-03  5.992137e-03
## ASV2910      1.829840e-03  1.909550e-03  1.992411e-03  2.078519e-03
## ASV2980      1.789228e-03  1.869469e-03  1.953059e-03  2.040114e-03
## ASV3307      3.887919e-03  4.061174e-03  4.241547e-03  4.429272e-03
## ASV3474      2.390654e-03  2.502133e-03  2.618704e-03  2.740587e-03
## ASV3502      2.860286e-03  2.989632e-03  3.124525e-03  3.265177e-03
## ASV4236      4.109262e-03  4.287692e-03  4.473107e-03  4.665712e-03
## ASV4842     -8.317731e-04 -8.718433e-04 -9.137865e-04 -9.576802e-04
## ASV4894     -1.857650e-03 -1.940450e-03 -2.026653e-03 -2.116372e-03
## ASV5290      1.482455e-03  1.549661e-03  1.619772e-03  1.692904e-03
## ASV5501      7.393139e-04  7.727104e-04  8.075621e-04  8.439294e-04
## ASV5795      9.072188e-04  9.484795e-04  9.915393e-04  1.036470e-03
## ASV5987     -5.197790e-03 -5.429497e-03 -5.670731e-03 -5.921808e-03
## ASV6267     -5.858289e-03 -6.119396e-03 -6.391234e-03 -6.674159e-03
## ASV6862      2.366821e-03  2.467598e-03  2.572156e-03  2.680594e-03
## ASV7145      8.724969e-04  9.072544e-04  9.431291e-04  9.801370e-04
## ASV7673     -1.857464e-03 -1.940247e-03 -2.026431e-03 -2.116130e-03
## ASV7789      8.017107e-04  8.406871e-04  8.815961e-04  9.245364e-04
## ASV7809     -3.040775e-05 -3.083076e-05 -3.117196e-05 -3.141807e-05
## ASV8002     -2.346398e-03 -2.450966e-03 -2.559831e-03 -2.673135e-03
## ASV8205      7.887656e-04  8.238458e-04  8.603996e-04  8.984833e-04
## ASV9155     -6.430255e-04 -6.713099e-04 -7.007141e-04 -7.312706e-04
## ASV9221      5.538484e-05  5.755339e-05  5.979452e-05  6.210984e-05
## ASV9311     -3.766435e-03 -3.934260e-03 -4.108978e-03 -4.290819e-03
## ASV9557     -2.572220e-03 -2.686814e-03 -2.806113e-03 -2.930273e-03
## ASV9936     -5.193785e-03 -5.425131e-03 -5.665973e-03 -5.916625e-03
## ASV1445      3.421834e-03  3.577467e-03  3.739856e-03  3.909266e-03
## ASV4232      1.528563e-03  1.600133e-03  1.675011e-03  1.753348e-03
## ASV6479      2.579631e-04  2.738970e-04  2.909252e-04  3.091288e-04
## ASV0142     -2.134795e-03 -2.227622e-03 -2.324100e-03 -2.424338e-03
## ASV0378     -7.624342e-05 -7.717035e-05 -7.790257e-05 -7.841066e-05
## ASV1122      3.372065e-03  3.526155e-03  3.686997e-03  3.854863e-03
## ASV0123     -1.888129e-03 -1.970082e-03 -2.055244e-03 -2.143712e-03
## ASV2064      1.069401e-03  1.114052e-03  1.160331e-03  1.208281e-03
## ASV4459     -4.903386e-04 -5.132027e-04 -5.370923e-04 -5.620492e-04
## ASV0448      7.401458e-04  7.756837e-04  8.129245e-04  8.519482e-04
## ASV0397      1.563687e-03  1.634666e-03  1.708704e-03  1.785918e-03
## ASV0485      2.037438e-03  2.128053e-03  2.222413e-03  2.320648e-03
## ASV1566      3.245932e-03  3.392120e-03  3.544517e-03  3.703356e-03
## ASV1365      2.068832e-03  2.160754e-03  2.256470e-03  2.356108e-03
## ASV1065      3.905309e-03  4.082347e-03  4.267003e-03  4.459571e-03
## ASV0722     -2.265377e-04 -2.370591e-04 -2.480704e-04 -2.595953e-04
## ASV12660    -2.120519e-03 -2.213120e-03 -2.309376e-03 -2.409397e-03
## ASV0223      3.277273e-04  3.425081e-04  3.579148e-04  3.739702e-04
## ASV0229      8.193450e-04  8.573002e-04  8.969587e-04  9.383916e-04
## ASV0877      6.574644e-05  6.715662e-05  6.851506e-05  6.981277e-05
## ASV0983      2.058395e-03  2.148958e-03  2.243164e-03  2.341128e-03
## ASV0626     -1.332042e-04 -1.357911e-04 -1.381806e-04 -1.403385e-04
## ASV4146     -1.197817e-04 -1.259520e-04 -1.324519e-04 -1.393002e-04
## ASV4175     -2.504628e-03 -2.618698e-03 -2.737706e-03 -2.861843e-03
## ASV2082     -1.204494e-03 -1.264066e-03 -1.326685e-03 -1.392515e-03
## ASV2272      1.132078e-03  1.182728e-03  1.235511e-03  1.290506e-03
## ASV2245     -1.825595e-03 -1.908912e-03 -1.995849e-03 -2.086547e-03
## ASV0590     -1.553159e-03 -1.630143e-03 -1.711062e-03 -1.796126e-03
## ASV0217     -1.594715e-04 -1.618924e-04 -1.639932e-04 -1.657253e-04
## ASV0416      1.386274e-03  1.443983e-03  1.503708e-03  1.565487e-03
## ASV1056      1.631563e-03  1.707731e-03  1.787380e-03  1.870662e-03
## ASV7777     -2.448602e-03 -2.561714e-03 -2.679885e-03 -2.803326e-03
## ASV0455      3.081969e-04  3.220186e-04  3.364131e-04  3.513994e-04
## ASV0604      9.997160e-04  1.047606e-03  1.097788e-03  1.150370e-03
## ASV6100     -1.737732e-03 -1.818140e-03 -1.902154e-03 -1.989924e-03
## ASV11359    -3.852968e-03 -4.026050e-03 -4.206397e-03 -4.394268e-03
## ASV6604      7.006387e-04  7.335077e-04  7.678978e-04  8.038776e-04
## ASV5004     -1.104294e-03 -1.154935e-03 -1.207803e-03 -1.262986e-03
## ASV1483     -6.982453e-04 -7.307303e-04 -7.646805e-04 -8.001574e-04
## ASV9773     -1.729945e-03 -1.809342e-03 -1.892239e-03 -1.978778e-03
## ASV4059      1.301203e-03  1.364580e-03  1.431099e-03  1.500919e-03
## ASV1193      2.093196e-03  2.187477e-03  2.285768e-03  2.388218e-03
## ASV4610     -2.659053e-04 -2.743839e-04 -2.829071e-04 -2.914492e-04
## ASV0742     -4.484215e-04 -4.651156e-04 -4.822058e-04 -4.996798e-04
## ASV1502      3.844210e-05  3.782946e-05  3.698778e-05  3.589135e-05
## ASV0195     -8.209409e-05 -8.700407e-05 -9.223357e-05 -9.780429e-05
## ASV1213      1.770761e-03  1.847056e-03  1.926273e-03  2.008491e-03
## ASV1648     -1.626571e-03 -1.701685e-03 -1.780155e-03 -1.862122e-03
## ASV6984     -1.514204e-03 -1.584034e-03 -1.656973e-03 -1.733149e-03
## ASV0396     -1.441709e-04 -1.469841e-04 -1.496059e-04 -1.520042e-04
## ASV4297      2.487537e-03  2.595247e-03  2.707162e-03  2.823408e-03
## ASV2622      3.282807e-03  3.426830e-03  3.576632e-03  3.732400e-03
## ASV3512      1.158702e-03  1.214245e-03  1.272465e-03  1.333491e-03
## ASV2411      2.038368e-03  2.132932e-03  2.231752e-03  2.335005e-03
## ASV2291     -1.100544e-03 -1.156270e-03 -1.214948e-03 -1.276744e-03
## ASV0807      2.356997e-03  2.466959e-03  2.581909e-03  2.702058e-03
## ASV1292      7.676427e-04  8.007800e-04  8.351907e-04  8.709099e-04
## ASV1035      2.204979e-03  2.300706e-03  2.400173e-03  2.503489e-03
## ASV0070     -7.041009e-05 -7.215417e-05 -7.384354e-05 -7.546464e-05
## ASV0255      2.049438e-04  2.131002e-04  2.214943e-04  2.301237e-04
## ASV0057     -8.110140e-04 -8.454360e-04 -8.811317e-04 -9.181318e-04
## ASV0077     -1.343926e-04 -1.393297e-04 -1.443778e-04 -1.495325e-04
## ASV0625      1.592252e-03  1.661007e-03  1.732411e-03  1.806536e-03
## ASV2464      1.064747e-02  1.110797e-02  1.158628e-02  1.208292e-02
## ASV1315      3.201419e-03  3.347637e-03  3.500298e-03  3.659667e-03
## ASV2673      2.763291e-03  2.893296e-03  3.029340e-03  3.171695e-03
## ASV2161      1.185733e-03  1.241263e-03  1.299357e-03  1.360130e-03
## ASV0337     -6.319218e-04 -6.608292e-04 -6.910089e-04 -7.225125e-04
## ASV7680     -3.946974e-03 -4.129152e-03 -4.319458e-03 -4.518228e-03
## ASV0611      2.068245e-03  2.163812e-03  2.263661e-03  2.367974e-03
## ASV3118     -2.466059e-03 -2.581892e-03 -2.703065e-03 -2.829814e-03
## ASV1284      1.573565e-03  1.645423e-03  1.720289e-03  1.798257e-03
## ASV0889      1.481694e-03  1.546969e-03  1.614900e-03  1.685577e-03
## ASV4649     -8.348646e-04 -8.729318e-04 -9.126545e-04 -9.540975e-04
## ASV1108     -1.912000e-03 -2.003112e-03 -2.098547e-03 -2.198505e-03
## ASV0738      4.642894e-04  4.917358e-04  5.209402e-04  5.520213e-04
## ASV0473     -1.861415e-04 -1.961628e-04 -2.067620e-04 -2.179743e-04
## ASV0598     -1.100928e-03 -1.148512e-03 -1.197948e-03 -1.249293e-03
## ASV0429      1.583495e-03  1.653397e-03  1.726129e-03  1.801784e-03
## ASV1549      2.101518e-03  2.200868e-03  2.304871e-03  2.413740e-03
## ASV1203      1.734658e-03  1.811318e-03  1.891097e-03  1.974097e-03
## ASV4532      1.682245e-05  1.633509e-05  1.572340e-05  1.497461e-05
## ASV0274     -2.558335e-04 -2.651154e-04 -2.746088e-04 -2.843078e-04
## ASV0163     -1.444281e-03 -1.506500e-03 -1.571114e-03 -1.638190e-03
## ASV1298      5.897849e-04  6.147622e-04  6.406679e-04  6.675269e-04
## ASV9424     -3.408890e-03 -3.567059e-03 -3.732370e-03 -3.905128e-03
## ASV0412      2.901898e-03  3.030510e-03  3.164390e-03  3.303717e-03
## ASV0284      7.098392e-04  7.389662e-04  7.690708e-04  8.001663e-04
## ASV0620     -8.040457e-04 -8.442755e-04 -8.865747e-04 -9.310521e-04
## ASV0153     -2.370752e-03 -2.482298e-03 -2.599023e-03 -2.721160e-03
## ASV0498      9.125729e-04  9.560644e-04  1.001593e-03  1.049248e-03
## ASV0097      6.126101e-04  6.413349e-04  6.713882e-04  7.028300e-04
## ASV0104     -4.024719e-03 -4.205580e-03 -4.394104e-03 -4.590578e-03
## ASV1282      1.063595e-03  1.111789e-03  1.162013e-03  1.214334e-03
## ASV3883     -1.217108e-03 -1.275181e-03 -1.336004e-03 -1.399703e-03
## ASV0801      7.784288e-04  8.156516e-04  8.546438e-04  8.954875e-04
## ASV1611     -2.784625e-03 -2.913988e-03 -3.049205e-03 -3.190524e-03
## ASV0227     -6.009972e-04 -6.305755e-04 -6.616371e-04 -6.942573e-04
## ASV0833      8.008997e-04  8.378956e-04  8.765447e-04  9.169152e-04
## ASV0718      3.907596e-03  4.086079e-03  4.272370e-03  4.466779e-03
## ASV1139      5.151930e-04  5.348392e-04  5.549902e-04  5.756344e-04
## ASV0766     -6.816392e-04 -7.142277e-04 -7.483718e-04 -7.841451e-04
## ASV2091      4.001847e-03  4.173892e-03  4.352542e-03  4.537985e-03
## ASV1238     -1.395824e-03 -1.452288e-03 -1.510718e-03 -1.571168e-03
## ASV9193     -5.724186e-04 -6.069452e-04 -6.436098e-04 -6.825378e-04
## ASV0290      6.732107e-05  6.883924e-05  7.029308e-05  7.166986e-05
## ASV0231      1.270370e-03  1.326815e-03  1.385584e-03  1.446755e-03
## ASV0185      5.049380e-04  5.319533e-04  5.604980e-04  5.906625e-04
## ASV2330      1.165781e-03  1.215120e-03  1.266266e-03  1.319259e-03
## ASV3119     -6.800387e-04 -7.145262e-04 -7.508290e-04 -7.890463e-04
## ASV2368     -1.744045e-03 -1.826633e-03 -1.913105e-03 -2.003642e-03
## ASV0122     -5.646655e-04 -5.892612e-04 -6.148323e-04 -6.414098e-04
## ASV1044      1.874879e-03  1.964044e-03  2.057432e-03  2.155239e-03
## ASV0160     -9.410537e-04 -9.806336e-04 -1.021654e-03 -1.064147e-03
## ASV0326      2.737772e-04  2.861598e-04  2.990724e-04  3.125349e-04
## ASV1388      4.782125e-03  4.996374e-03  5.219623e-03  5.452198e-03
## ASV0792      2.888019e-03  3.015117e-03  3.147337e-03  3.284844e-03
## ASV0036     -7.670783e-04 -8.029930e-04 -8.405584e-04 -8.798472e-04
## ASV2125      2.646521e-03  2.764613e-03  2.887618e-03  3.015710e-03
## ASV1075      1.278151e-04  1.339514e-04  1.403863e-04  1.471345e-04
## ASV0390      1.448973e-03  1.518670e-03  1.591738e-03  1.668343e-03
## ASV3790     -2.180573e-03 -2.280128e-03 -2.384046e-03 -2.492502e-03
## ASV1535     -4.174775e-04 -4.401464e-04 -4.641082e-04 -4.894385e-04
## ASV0263      1.972912e-03  2.061847e-03  2.154554e-03  2.251172e-03
## ASV0675      3.823748e-03  4.001929e-03  4.188206e-03  4.382927e-03
## ASV3348      4.094197e-04  4.294391e-04  4.504576e-04  4.725263e-04
## ASV0058     -1.265347e-03 -1.320908e-03 -1.378709e-03 -1.438825e-03
## ASV4142      1.519643e-03  1.586598e-03  1.656265e-03  1.728732e-03
## ASV0059     -1.045144e-03 -1.090675e-03 -1.138008e-03 -1.187202e-03
## ASV0013     -1.451209e-03 -1.516773e-03 -1.585147e-03 -1.656438e-03
## ASV0033     -7.306627e-04 -7.649450e-04 -8.008096e-04 -8.383266e-04
## ASV4354     -9.730435e-04 -1.017461e-03 -1.063826e-03 -1.112217e-03
## ASV0022     -5.777095e-04 -6.048981e-04 -6.333493e-04 -6.631200e-04
## ASV0134     -6.288117e-04 -6.589629e-04 -6.905660e-04 -7.236913e-04
## ASV0415      7.361134e-05  7.949478e-05  8.584141e-05  9.268513e-05
## ASV10103    -3.454381e-03 -3.614580e-03 -3.781996e-03 -3.956934e-03
## ASV1613      2.622384e-03  2.737229e-03  2.856649e-03  2.980788e-03
## ASV0135     -4.223072e-04 -4.397497e-04 -4.577848e-04 -4.764204e-04
## ASV0469     -3.319203e-03 -3.465467e-03 -3.617666e-03 -3.775999e-03
## ASV0471      2.453655e-03  2.566781e-03  2.684914e-03  2.808254e-03
## ASV0451     -3.758901e-04 -3.957603e-04 -4.167485e-04 -4.389218e-04
## ASV0747      8.650253e-04  9.057911e-04  9.484411e-04  9.930580e-04
## ASV1314     -1.085833e-03 -1.137770e-03 -1.192195e-03 -1.249226e-03
## ASV0425     -4.731335e-03 -4.934493e-03 -5.145444e-03 -5.364408e-03
## ASV0559     -1.348531e-03 -1.407995e-03 -1.469896e-03 -1.534320e-03
## ASV0148     -7.462827e-04 -7.771172e-04 -8.090168e-04 -8.420000e-04
## ASV0129     -2.115141e-04 -2.167414e-04 -2.218179e-04 -2.267063e-04
## ASV1072      5.234666e-04  5.448204e-04  5.668974e-04  5.897100e-04
## ASV2390      1.789909e-03  1.865834e-03  1.944550e-03  2.026121e-03
## ASV0548      1.599384e-03  1.671723e-03  1.747171e-03  1.825850e-03
## ASV0168     -1.069387e-03 -1.116415e-03 -1.165348e-03 -1.216247e-03
## ASV0066     -8.833150e-04 -9.230710e-04 -9.645120e-04 -1.007700e-03
## ASV0468     -5.729531e-04 -5.991025e-04 -6.263948e-04 -6.548757e-04
## ASV0172     -2.594360e-04 -2.692357e-04 -2.792888e-04 -2.895911e-04
## ASV0236     -4.691611e-04 -4.843134e-04 -4.995977e-04 -5.149766e-04
## ASV0250      6.201296e-04  6.543362e-04  6.905446e-04  7.288766e-04
## ASV0338      5.749801e-04  6.039833e-04  6.344784e-04  6.665417e-04
## ASV0450     -5.240049e-05 -5.559098e-05 -5.899466e-05 -6.262670e-05
## ASV0377      1.222082e-03  1.277121e-03  1.334496e-03  1.394292e-03
## ASV1022      1.592013e-04  1.665547e-04  1.742388e-04  1.822680e-04
## ASV6174     -1.483319e-04 -1.557637e-04 -1.635809e-04 -1.718046e-04
## ASV0786      1.014599e-04  1.043561e-04  1.072193e-04  1.100340e-04
## ASV0053     -1.133451e-03 -1.185372e-03 -1.239576e-03 -1.296154e-03
## ASV0697     -8.961131e-04 -9.352924e-04 -9.760425e-04 -1.018415e-03
## ASV0785      1.672588e-03  1.746992e-03  1.824496e-03  1.905214e-03
## ASV1967     -1.531845e-03 -1.599269e-03 -1.669418e-03 -1.742380e-03
## ASV0385      2.252059e-04  2.374539e-04  2.503862e-04  2.640396e-04
## ASV0295      7.165889e-05  7.653823e-05  8.177678e-05  8.740185e-05
## ASV0072     -1.074605e-03 -1.121138e-03 -1.169486e-03 -1.219705e-03
## ASV0157     -3.859785e-04 -4.011357e-04 -4.167268e-04 -4.327482e-04
## ASV0501      2.817569e-03  2.950167e-03  3.088821e-03  3.233784e-03
## ASV10729    -3.309476e-03 -3.462490e-03 -3.622362e-03 -3.789378e-03
## ASV1470      1.857134e-03  1.929697e-03  2.004427e-03  2.081330e-03
## ASV0050     -2.538160e-03 -2.651368e-03 -2.769298e-03 -2.892122e-03
## ASV0411     -4.615608e-04 -4.823617e-04 -5.040626e-04 -5.267004e-04
## ASV0549      8.220550e-04  8.603563e-04  9.004114e-04  9.422982e-04
## ASV0184      2.527435e-04  2.640534e-04  2.758382e-04  2.881154e-04
## ASV0705      6.595814e-04  6.897480e-04  7.212315e-04  7.540833e-04
## ASV1715      1.486518e-03  1.554040e-03  1.624484e-03  1.697963e-03
## ASV0603      2.376487e-04  2.489447e-04  2.607784e-04  2.731755e-04
## ASV0826      2.004560e-03  2.093148e-03  2.185354e-03  2.281302e-03
## ASV0034     -8.068434e-04 -8.422017e-04 -8.789717e-04 -9.171977e-04
## ASV0838      1.110790e-03  1.158461e-03  1.207919e-03  1.259208e-03
## ASV0614     -9.303907e-04 -9.723557e-04 -1.016109e-03 -1.061719e-03
## ASV0014     -1.457228e-03 -1.522708e-03 -1.590964e-03 -1.662097e-03
## ASV0585     -1.274246e-04 -1.337298e-04 -1.403671e-04 -1.473561e-04
## ASV0016     -1.528693e-03 -1.597415e-03 -1.669052e-03 -1.743712e-03
## ASV5394     -1.493888e-03 -1.562158e-03 -1.633414e-03 -1.707774e-03
## ASV0666      2.762157e-03  2.882749e-03  3.008119e-03  3.138413e-03
## ASV2085      5.842509e-04  6.031635e-04  6.222167e-04  6.413576e-04
## ASV0003     -1.060327e-03 -1.107915e-03 -1.157514e-03 -1.209201e-03
## ASV0346      2.774410e-04  2.921900e-04  3.077631e-04  3.242077e-04
## ASV0267     -1.283093e-04 -1.321915e-04 -1.360533e-04 -1.398757e-04
## ASV0353      8.843813e-04  9.275997e-04  9.729402e-04  1.020505e-03
## ASV2419      2.888429e-03  3.016264e-03  3.149330e-03  3.287803e-03
## ASV0447      1.226273e-03  1.284138e-03  1.344691e-03  1.408053e-03
## ASV0654      1.993958e-03  2.084710e-03  2.179399e-03  2.278179e-03
## ASV0151      1.742103e-04  1.836427e-04  1.936230e-04  2.041855e-04
## ASV0065     -7.994940e-04 -8.343721e-04 -8.706359e-04 -9.083292e-04
## ASV0527      2.148646e-03  2.245474e-03  2.346423e-03  2.451648e-03
## ASV4055     -5.113959e-04 -5.365630e-04 -5.630006e-04 -5.907753e-04
## ASV0166     -1.067267e-03 -1.110978e-03 -1.156189e-03 -1.202926e-03
## ASV0417     -8.074481e-04 -8.418977e-04 -8.776354e-04 -9.146932e-04
## ASV0078     -5.739504e-04 -5.984020e-04 -6.237715e-04 -6.500829e-04
## ASV0322     -6.631906e-04 -6.881371e-04 -7.137492e-04 -7.400226e-04
## ASV0156     -1.337937e-03 -1.396648e-03 -1.457748e-03 -1.521319e-03
## ASV0648     -4.166987e-03 -4.359958e-03 -4.561611e-03 -4.772311e-03
## ASV0407     -1.223745e-04 -1.283752e-04 -1.346659e-04 -1.412595e-04
## ASV2030     -5.550309e-04 -5.797027e-04 -6.054101e-04 -6.321931e-04
## ASV0300      3.625387e-04  3.804523e-04  3.992604e-04  4.190069e-04
## ASV1150     -2.907351e-05 -2.994348e-05 -3.081053e-05 -3.167104e-05
## ASV0958      1.061324e-03  1.111944e-03  1.164975e-03  1.220532e-03
## ASV0216     -1.187655e-03 -1.240093e-03 -1.294675e-03 -1.351475e-03
## ASV0446      1.794832e-03  1.879059e-03  1.967158e-03  2.059300e-03
## ASV0367     -1.338682e-03 -1.400147e-03 -1.464334e-03 -1.531355e-03
## ASV0200     -7.452852e-04 -7.787024e-04 -8.135334e-04 -8.498312e-04
## ASV0334     -4.384767e-04 -4.553575e-04 -4.727033e-04 -4.905100e-04
## ASV1311      4.884504e-04  5.095195e-04  5.313991e-04  5.541118e-04
## ASV0458      1.048878e-03  1.093415e-03  1.139593e-03  1.187451e-03
## ASV1371      1.147883e-04  1.202765e-04  1.260237e-04  1.320411e-04
## ASV0418      2.539338e-03  2.646399e-03  2.757389e-03  2.872402e-03
## ASV0004      2.481806e-04  2.589093e-04  2.700540e-04  2.816267e-04
## ASV1943      8.739968e-03  9.113839e-03  9.501929e-03  9.904635e-03
## ASV1495     -4.167568e-04 -4.401912e-04 -4.650431e-04 -4.914028e-04
## ASV0901     -1.667574e-03 -1.745093e-03 -1.826131e-03 -1.910841e-03
## ASV0628      7.554229e-04  7.876212e-04  8.210155e-04  8.556339e-04
## ASV0400      4.015724e-04  4.195930e-04  4.383664e-04  4.579185e-04
## ASV0116     -4.677310e-04 -4.892678e-04 -5.117654e-04 -5.352643e-04
## ASV0788      3.321351e-03  3.474297e-03  3.634046e-03  3.800878e-03
## ASV0117      2.955471e-04  3.098055e-04  3.247571e-04  3.404358e-04
## ASV3137     -8.374648e-06 -8.524002e-06 -8.656319e-06 -8.768544e-06
## ASV0001      2.980536e-04  3.107771e-04  3.239819e-04  3.376812e-04
## ASV1651      7.638067e-04  7.960321e-04  8.294394e-04  8.640571e-04
## ASV1692      2.778153e-03  2.906997e-03  3.041651e-03  3.182362e-03
## ASV0660      8.890644e-04  9.255344e-04  9.632108e-04  1.002105e-03
## ASV0508     -2.062925e-05 -2.219603e-05 -2.388477e-05 -2.570470e-05
## ASV1660     -8.127565e-04 -8.519576e-04 -8.930537e-04 -9.361351e-04
## ASV0233      5.868480e-04  6.133478e-04  6.409840e-04  6.698003e-04
## ASV1343     -1.874431e-03 -1.961332e-03 -2.052157e-03 -2.147073e-03
## ASV0209      8.442855e-04  8.807522e-04  9.186285e-04  9.579548e-04
## ASV0193     -1.116047e-03 -1.160913e-03 -1.207246e-03 -1.255068e-03
## ASV0357      2.234990e-04  2.348233e-04  2.467452e-04  2.592979e-04
## ASV0198      6.899089e-04  7.216293e-04  7.547469e-04  7.893169e-04
## ASV0007      3.113913e-04  3.245870e-04  3.382735e-04  3.524634e-04
## ASV1772     -4.554127e-04 -4.748783e-04 -4.950644e-04 -5.159865e-04
## ASV0009      2.905177e-04  3.027450e-04  3.154195e-04  3.285522e-04
## ASV0006     -3.990029e-05 -4.229364e-05 -4.483865e-05 -4.754498e-05
## ASV0011     -5.894569e-04 -6.166298e-04 -6.450123e-04 -6.746542e-04
## ASV0015      1.894549e-04  1.974529e-04  2.057422e-04  2.143294e-04
## ASV0017      2.057713e-04  2.144579e-04  2.234616e-04  2.327897e-04
## ASV0235     -7.397129e-04 -7.747557e-04 -8.114338e-04 -8.498201e-04
## ASV0382      3.135520e-04  3.292874e-04  3.458195e-04  3.631870e-04
## ASV2357      2.363693e-03  2.472584e-03  2.586328e-03  2.705127e-03
## ASV0567     -6.211129e-04 -6.490007e-04 -6.780761e-04 -7.083850e-04
## ASV0165      4.157053e-04  4.350726e-04  4.553194e-04  4.764834e-04
## ASV0005      4.977021e-04  5.197357e-04  5.426734e-04  5.665460e-04
## ASV0384     -2.161102e-05 -2.120201e-05 -2.064607e-05 -1.992551e-05
## ASV0002      8.554851e-05  8.937717e-05  9.336652e-05  9.752241e-05
## ASV3017      3.195088e-03  3.335076e-03  3.480675e-03  3.632068e-03
## ASV0091     -4.126932e-07 -3.497767e-07 -2.782844e-07 -1.975886e-07
## ASV0186     -1.312352e-03 -1.371985e-03 -1.434194e-03 -1.499078e-03
## ASV0370      3.900954e-04  4.084144e-04  4.275823e-04  4.476377e-04
## ASV0018      6.798568e-04  7.100549e-04  7.415016e-04  7.742406e-04
## ASV1377      1.029751e-02  1.075215e-02  1.122528e-02  1.171751e-02
## ASV0019      7.122549e-04  7.439221e-04  7.769012e-04  8.112388e-04
## ASV0023     -2.173386e-04 -2.278727e-04 -2.389169e-04 -2.504952e-04
## ASV2194      8.015294e-04  8.374057e-04  8.748103e-04  9.138033e-04
## ASV1155      1.551814e-03  1.622658e-03  1.696586e-03  1.773718e-03
## ASV0510     -1.125949e-03 -1.169347e-03 -1.214007e-03 -1.259934e-03
## ASV2371     -1.714687e-03 -1.788025e-03 -1.864132e-03 -1.943080e-03
## ASV0024     -2.923752e-04 -3.063390e-04 -3.209631e-04 -3.362775e-04
## ASV2452      1.976898e-03  2.061224e-03  2.148726e-03  2.239490e-03
## ASV2332     -2.311968e-03 -2.414546e-03 -2.521232e-03 -2.632143e-03
## ASV2591      1.615471e-03  1.696706e-03  1.782141e-03  1.871994e-03
## ASV0521      1.108296e-03  1.159825e-03  1.213683e-03  1.269970e-03
## ASV5542      9.690474e-04  1.014123e-03  1.061229e-03  1.110452e-03
## ASV0336     -3.421155e-04 -3.560227e-04 -3.704202e-04 -3.853214e-04
## ASV10102     2.037379e-03  2.132513e-03  2.231992e-03  2.336007e-03
## ASV16823    -2.858097e-03 -2.979917e-03 -3.106306e-03 -3.237381e-03
## ASV3104      1.577030e-02  1.644237e-02  1.713963e-02  1.786274e-02
## ASV0781      1.853232e-03  1.938139e-03  2.026785e-03  2.119323e-03
## ASV10899     1.195980e-03  1.256270e-03  1.319698e-03  1.386429e-03
## ASV11222    -4.991088e-03 -5.203774e-03 -5.424433e-03 -5.653270e-03
## ASV11327    -4.488518e-03 -4.679758e-03 -4.878163e-03 -5.083919e-03
## ASV12458    -4.989541e-03 -5.202094e-03 -5.422608e-03 -5.651289e-03
## ASV1636      4.141687e-04  4.340548e-04  4.548920e-04  4.767246e-04
## ASV1890     -3.220672e-03 -3.356129e-03 -3.496498e-03 -3.641892e-03
## ASV2898      3.863803e-03  4.034729e-03  4.212634e-03  4.397751e-03
## ASV8328      2.157592e-04  2.359876e-04  2.580194e-04  2.820050e-04
## ASV0709     -4.298501e-03 -4.490382e-03 -4.690257e-03 -4.898411e-03
## ASV0856      3.046543e-03  3.190322e-03  3.340800e-03  3.498278e-03
## ASV0909     -1.712778e-04 -1.692096e-04 -1.661890e-04 -1.621059e-04
## ASV0937     -2.516690e-03 -2.631692e-03 -2.751742e-03 -2.877045e-03
## ASV11390    -7.066493e-03 -7.367468e-03 -7.679712e-03 -8.003516e-03
## ASV11966     1.747479e-03  1.831955e-03  1.920533e-03  2.013411e-03
## ASV12990     1.148676e-03  1.201021e-03  1.255636e-03  1.312610e-03
## ASV14797     1.934059e-03  2.018915e-03  2.107174e-03  2.198944e-03
## ASV14904    -1.003079e-02 -1.045801e-02 -1.090123e-02 -1.136086e-02
## ASV15304     9.438220e-04  9.920335e-04  1.042799e-03  1.096257e-03
## ASV16696    -3.547857e-03 -3.698948e-03 -3.855695e-03 -4.018244e-03
## ASV1690      6.178689e-03  6.469322e-03  6.773350e-03  7.091353e-03
## ASV2029      4.370530e-03  4.564694e-03  4.766863e-03  4.977314e-03
## ASV2834      7.092109e-03  7.415757e-03  7.753522e-03  8.105958e-03
## ASV4003      4.332867e-03  4.542251e-03  4.761834e-03  4.992116e-03
## ASV4064      2.658125e-03  2.778033e-03  2.903049e-03  3.033364e-03
## ASV4294      1.552357e-03  1.631019e-03  1.713826e-03  1.801006e-03
## ASV4609      8.055115e-04  8.401268e-04  8.760933e-04  9.134551e-04
## ASV6283     -3.319482e-03 -3.460867e-03 -3.607547e-03 -3.759659e-03
## ASV6491     -4.733018e-03 -4.934576e-03 -5.143681e-03 -5.360527e-03
## ASV7453      2.218625e-03  2.326308e-03  2.439241e-03  2.557676e-03
## ASV7959      6.031032e-04  6.368332e-04  6.725788e-04  7.104654e-04
## ASV8219      4.878078e-02  5.085801e-02  5.301300e-02  5.524777e-02
## ASV8547     -4.243933e-03 -4.424624e-03 -4.612076e-03 -4.806465e-03
## ASV9319      1.887161e-03  1.975597e-03  2.068100e-03  2.164848e-03
## ASV9382     -8.185442e-03 -8.533920e-03 -8.895437e-03 -9.270330e-03
## ASV11516    -5.519502e-03 -5.754446e-03 -5.998178e-03 -6.250924e-03
## ASV14377    -4.006531e-03 -4.177047e-03 -4.353938e-03 -4.537369e-03
## ASV1867      3.450085e-03  3.609365e-03  3.775772e-03  3.949603e-03
## ASV1895      5.830486e-04  6.089417e-04  6.358672e-04  6.638531e-04
## ASV3168      1.867089e-03  1.948638e-03  2.033414e-03  2.121514e-03
## ASV4449      1.207402e-02  1.261580e-02  1.318046e-02  1.376885e-02
## ASV6596      2.365002e-03  2.481172e-03  2.603170e-03  2.731294e-03
## ASV7492     -5.022581e-04 -5.176394e-04 -5.330381e-04 -5.484009e-04
## ASV9854     -1.035152e-03 -1.077946e-03 -1.122226e-03 -1.168021e-03
## ASV6296      8.990514e-02  9.373069e-02  9.769923e-02  1.018144e-01
## ASV4201      1.048126e-03  1.104932e-03  1.165016e-03  1.228576e-03
## ASV0552      2.244030e-03  2.347768e-03  2.456148e-03  2.569362e-03
## ASV3671     -1.123881e-03 -1.171850e-03 -1.221646e-03 -1.273325e-03
## ASV3529     -5.333043e-04 -5.514945e-04 -5.699563e-04 -5.886589e-04
## ASV1060      8.656052e-04  9.057893e-04  9.477924e-04  9.916926e-04
## ASV0239     -8.832250e-04 -9.197945e-04 -9.576211e-04 -9.967245e-04
## ASV5711     -3.515375e-03 -3.670082e-03 -3.831053e-03 -3.998499e-03
## ASV4152     -5.745952e-03 -6.002851e-03 -6.270498e-03 -6.549279e-03
## ASV1461      2.618363e-03  2.730528e-03  2.846938e-03  2.967705e-03
## ASV2877      1.353362e-03  1.411174e-03  1.471154e-03  1.533358e-03
## ASV0012      1.903004e-04  1.989725e-04  2.080220e-04  2.174635e-04
## ASV9823      3.973817e-04  4.095526e-04  4.218067e-04  4.341184e-04
## ASV0008      2.029903e-04  2.121636e-04  2.217297e-04  2.317033e-04
## ASV7832     -3.605678e-03 -3.768767e-03 -3.938858e-03 -4.116220e-03
## ASV1915     -6.504156e-05 -6.614934e-05 -6.715622e-05 -6.804778e-05
## ASV0055      1.454123e-05  1.420563e-05  1.376275e-05  1.319983e-05
## ASV0032      3.789272e-04  3.954869e-04  4.127060e-04  4.306054e-04
## ASV2977     -5.007552e-03 -5.228975e-03 -5.459427e-03 -5.699210e-03
## ASV0466      3.686106e-03  3.841803e-03  4.003187e-03  4.170390e-03
## ASV3866      2.580647e-03  2.699805e-03  2.824292e-03  2.954332e-03
## ASV0040      6.820599e-04  7.132334e-04  7.457717e-04  7.797291e-04
## ASV0496     -2.748739e-04 -2.914740e-04 -3.091618e-04 -3.280119e-04
## ASV0052      8.668925e-04  9.059690e-04  9.467086e-04  9.891737e-04
## ASV3828     -5.322247e-03 -5.560336e-03 -5.808434e-03 -6.066910e-03
## ASV1930      1.677758e-03  1.753435e-03  1.832324e-03  1.914544e-03
## ASV2126      2.060438e-03  2.152218e-03  2.247809e-03  2.347344e-03
## ASV0793      2.363256e-03  2.471719e-03  2.584962e-03  2.703176e-03
## ASV0299     -1.876541e-04 -1.961322e-04 -2.049768e-04 -2.142031e-04
## ASV0208      1.698165e-03  1.777214e-03  1.859845e-03  1.946209e-03
## ASV0511     -9.484988e-04 -9.889398e-04 -1.030903e-03 -1.074429e-03
## ASV1123     -3.001726e-03 -3.127797e-03 -3.258427e-03 -3.393717e-03
## ASV0099     -8.772490e-05 -9.057574e-05 -9.345060e-05 -9.634192e-05
## ASV0752     -9.623828e-04 -1.009137e-03 -1.058190e-03 -1.109658e-03
## ASV0883      1.205850e-03  1.262241e-03  1.321208e-03  1.382865e-03
## ASV0683      2.516771e-03  2.634692e-03  2.758031e-03  2.887028e-03
## ASV4117     -6.089200e-03 -6.360865e-03 -6.643857e-03 -6.938583e-03
## ASV2172      4.861830e-04  5.070033e-04  5.286157e-04  5.510420e-04
## ASV0330     -7.095014e-04 -7.415610e-04 -7.750019e-04 -8.098784e-04
## ASV0728      3.744233e-03  3.913797e-03  4.090641e-03  4.275042e-03
## ASV0499      9.185454e-04  9.616298e-04  1.006703e-03  1.053853e-03
## ASV0120     -1.557389e-03 -1.627577e-03 -1.700746e-03 -1.777005e-03
## ASV1446      1.478118e-03  1.537475e-03  1.598694e-03  1.661783e-03
## ASV17171    -2.780587e-03 -2.906146e-03 -3.037084e-03 -3.173609e-03
## ASV0533      2.640347e-04  2.768417e-04  2.902758e-04  3.043679e-04
## ASV2495     -1.032049e-03 -1.082846e-03 -1.136209e-03 -1.192272e-03
## ASV5582      1.181913e-03  1.227688e-03  1.274752e-03  1.323097e-03
## ASV1488      1.102112e-03  1.157754e-03  1.216203e-03  1.277592e-03
## ASV0682      6.885327e-04  7.213470e-04  7.557217e-04  7.917303e-04
## ASV0068     -7.393258e-04 -7.730682e-04 -8.082777e-04 -8.450111e-04
## ASV1987     -2.799285e-03 -2.932618e-03 -3.072279e-03 -3.218561e-03
## ASV0035     -1.243436e-04 -1.320728e-04 -1.403292e-04 -1.491509e-04
## ASV7192     -2.053659e-03 -2.142832e-03 -2.235495e-03 -2.331749e-03
## ASV0873      6.468713e-04  6.462129e-04  6.429519e-04  6.367796e-04
## ASV4749     -4.600404e-05 -5.514398e-05 -6.531864e-05 -7.662528e-05
## ASV2174      1.918197e-03  1.995212e-03  2.074777e-03  2.156938e-03
## ASV1476     -1.290730e-03 -1.350197e-03 -1.412323e-03 -1.477222e-03
## ASV0740     -4.465064e-03 -4.672368e-03 -4.889036e-03 -5.115466e-03
## ASV0170     -5.734307e-04 -5.995798e-04 -6.268683e-04 -6.553409e-04
## ASV2466     -4.290168e-03 -4.484707e-03 -4.687649e-03 -4.899321e-03
## ASV1709      1.764299e-03  1.840570e-03  1.919813e-03  2.002119e-03
## ASV6170     -9.999279e-03 -1.043897e-02 -1.089676e-02 -1.137331e-02
## ASV3673      2.975658e-03  3.104212e-03  3.237883e-03  3.376845e-03
## ASV1745      4.195825e-04  4.313210e-04  4.430386e-04  4.547023e-04
## ASV0380     -2.253394e-03 -2.331706e-03 -2.411567e-03 -2.492912e-03
## ASV0426      1.699046e-04  1.821240e-04  1.952327e-04  2.092925e-04
## ASV0202      3.671088e-05  4.142906e-05  4.662004e-05  5.232506e-05
## ASV6350     -3.241403e-03 -3.376501e-03 -3.516614e-03 -3.661896e-03
## ASV0713     -1.407537e-03 -1.472188e-03 -1.539707e-03 -1.610212e-03
## ASV1822      1.323570e-04  1.407866e-04  1.497581e-04  1.593037e-04
## ASV4569      4.204610e-03  4.386758e-03  4.576150e-03  4.773029e-03
## ASV0030     -3.852112e-04 -4.031640e-04 -4.219244e-04 -4.415255e-04
## ASV0331      1.533894e-03  1.606326e-03  1.682135e-03  1.761472e-03
## ASV2981      4.356380e-03  4.558092e-03  4.768809e-03  4.988898e-03
## ASV0828     -8.425877e-04 -9.036653e-04 -9.692694e-04 -1.039725e-03
## ASV2440      3.795393e-03  3.970772e-03  4.153983e-03  4.345348e-03
## ASV3006     -1.909391e-02 -1.981047e-02 -2.054725e-02 -2.130440e-02
## ASV3875      1.775146e-01  1.841756e-01  1.910244e-01  1.980625e-01
## ASV4511      2.146377e-03  2.246815e-03  2.351871e-03  2.461748e-03
## ASV4700     -7.019910e-03 -7.283286e-03 -7.554089e-03 -7.832373e-03
## ASV5804     -1.648399e-01 -1.710237e-01 -1.773817e-01 -1.839154e-01
## ASV6826      3.098013e-03  3.244660e-03  3.398189e-03  3.558914e-03
## ASV7280      2.904747e-03  3.044579e-03  3.191047e-03  3.344447e-03
## ASV7535     -7.018540e-03 -7.281824e-03 -7.552531e-03 -7.830714e-03
## ASV0651     -1.492840e-03 -1.556698e-03 -1.622946e-03 -1.691642e-03
## ASV0913      3.500102e-03  3.663833e-03  3.835099e-03  4.014235e-03
## ASV10832    -7.488534e-03 -7.769413e-03 -8.058209e-03 -8.354979e-03
## ASV1117     -7.756300e-03 -8.091876e-03 -8.440712e-03 -8.803239e-03
## ASV11329     1.289770e-03  1.358526e-03  1.431094e-03  1.507687e-03
## ASV13209     2.929986e-04  3.184780e-04  3.459072e-04  3.754086e-04
## ASV1345      1.891880e-03  1.982337e-03  2.076933e-03  2.175830e-03
## ASV1719     -1.054465e-02 -1.094012e-02 -1.134674e-02 -1.176458e-02
## ASV1886      2.088431e-03  2.180528e-03  2.276451e-03  2.376345e-03
## ASV2158     -9.969528e-07  1.221042e-05  2.687388e-05  4.309328e-05
## ASV2189      3.545534e-03  3.705179e-03  3.871646e-03  4.045196e-03
## ASV2257      3.660231e-03  3.823384e-03  3.993480e-03  4.170797e-03
## ASV2283      8.167184e-03  8.473387e-03  8.788210e-03  9.111717e-03
## ASV2328      5.031202e-03  5.219807e-03  5.413719e-03  5.612979e-03
## ASV2434     -4.971115e-03 -5.181832e-03 -5.400672e-03 -5.627903e-03
## ASV2648      9.182143e-03  9.526232e-03  9.879996e-03  1.024350e-02
## ASV2698      9.739115e-03  1.018681e-02  1.065450e-02  1.114304e-02
## ASV2775      2.940023e-03  3.063316e-03  3.191128e-03  3.323575e-03
## ASV3171      4.425460e-03  4.591242e-03  4.761682e-03  4.936810e-03
## ASV3227      4.513473e-03  4.700477e-03  4.894129e-03  5.094582e-03
## ASV3397      2.248616e-03  2.354804e-03  2.465747e-03  2.581620e-03
## ASV3444      6.479684e-03  6.750542e-03  7.031539e-03  7.322990e-03
## ASV3556      1.840378e-02  1.909294e-02  1.980144e-02  2.052942e-02
## ASV3606     -4.325376e-02 -4.487327e-02 -4.653821e-02 -4.824889e-02
## ASV4190      6.222353e-03  6.504812e-03  6.799580e-03  7.107156e-03
## ASV4197      3.823858e-03  3.982422e-03  4.146694e-03  4.316819e-03
## ASV4722      5.907357e-03  6.167964e-03  6.439269e-03  6.721652e-03
## ASV4765      3.175408e-03  3.322214e-03  3.475346e-03  3.635022e-03
## ASV4809      1.087206e-02  1.127898e-02  1.169731e-02  1.212712e-02
## ASV4846      5.402214e-03  5.648679e-03  5.905829e-03  6.174073e-03
## ASV4903     -1.470183e-04 -1.394309e-04 -1.305227e-04 -1.201872e-04
## ASV4944     -4.452598e-03 -4.619243e-03 -4.790558e-03 -4.966574e-03
## ASV5151      9.414332e-05  2.570070e-05 -5.118188e-05 -1.371981e-04
## ASV5413     -9.794398e-03 -1.016095e-02 -1.053777e-02 -1.092493e-02
## ASV5537     -1.052159e-02 -1.091530e-02 -1.132004e-02 -1.173589e-02
## ASV5688      8.843105e-03  9.173967e-03  9.514093e-03  9.863549e-03
## ASV5752      2.816401e-03  2.949934e-03  3.089512e-03  3.235366e-03
## ASV6122     -1.132749e-02 -1.175127e-02 -1.218693e-02 -1.263453e-02
## ASV6135      5.946282e-03  6.168716e-03  6.397377e-03  6.632307e-03
## ASV6188     -3.610120e-02 -3.745147e-02 -3.883953e-02 -4.026563e-02
## ASV6216      8.482361e-03  8.841661e-03  9.214578e-03  9.601515e-03
## ASV6242      5.943946e-03  6.166200e-03  6.394668e-03  6.629393e-03
## ASV6383      3.716283e-02  3.855223e-02  3.998047e-02  4.144780e-02
## ASV6781      8.270088e-03  8.579241e-03  8.897032e-03  9.223520e-03
## ASV6799     -1.570390e-02 -1.629087e-02 -1.689423e-02 -1.751410e-02
## ASV7374     -3.332107e-03 -3.456635e-03 -3.584642e-03 -3.716148e-03
## ASV7539     -4.445232e-03 -4.611340e-03 -4.782084e-03 -4.957497e-03
## ASV8591     -1.131254e-02 -1.173521e-02 -1.216967e-02 -1.261601e-02
## ASV8637      4.965921e-02  5.151437e-02  5.342129e-02  5.538031e-02
## ASV12796    -6.552938e-03 -6.797710e-03 -7.049309e-03 -7.307780e-03
## ASV1934      3.610768e-03  3.775787e-03  3.948056e-03  4.127868e-03
## ASV22549     4.090838e-04  4.371995e-04  4.672094e-04  4.992268e-04
## ASV29857    -2.541656e-03 -2.636587e-03 -2.734167e-03 -2.834411e-03
## ASV3215      3.872350e-03  4.054356e-03  4.244828e-03  4.444151e-03
## ASV3236     -6.551250e-03 -6.795904e-03 -7.047378e-03 -7.305718e-03
## ASV3954     -6.550383e-03 -6.794973e-03 -7.046379e-03 -7.304647e-03
## ASV4850      4.390747e-03  4.554675e-03  4.723171e-03  4.896263e-03
## ASV5225      4.239652e-02  4.397919e-02  4.560594e-02  4.727706e-02
## ASV5532     -2.264363e-03 -2.348882e-03 -2.435753e-03 -2.524993e-03
## ASV7258      2.069903e-03  2.183693e-03  2.304008e-03  2.431227e-03
## ASV9474     -5.959381e-04 -6.060599e-04 -6.153959e-04 -6.238411e-04
## ASV11857    -8.507756e-03 -8.825311e-03 -9.151711e-03 -9.487014e-03
## ASV1202     -5.402444e-03 -5.604067e-03 -5.811303e-03 -6.024190e-03
## ASV14742     1.665078e-03  1.750864e-03  1.841197e-03  1.936317e-03
## ASV16652     1.253782e-03  1.314215e-03  1.377421e-03  1.443503e-03
## ASV2019      4.171888e-03  4.349632e-03  4.534191e-03  4.725774e-03
## ASV2410     -9.437251e-03 -9.863934e-03 -1.030919e-02 -1.077378e-02
## ASV2718      2.374559e-03  2.486568e-03  2.603739e-03  2.726292e-03
## ASV2738      6.827685e-03  7.115868e-03  7.414771e-03  7.724683e-03
## ASV2876      3.927608e-03  4.074148e-03  4.224766e-03  4.379487e-03
## ASV3177      5.262675e-03  5.459001e-03  5.660789e-03  5.868072e-03
## ASV4367      6.502528e-03  6.745077e-03  6.994370e-03  7.250450e-03
## ASV4635      2.275087e-03  2.391809e-03  2.514510e-03  2.643474e-03
## ASV4896      1.750642e-03  1.851204e-03  1.957808e-03  2.070814e-03
## ASV4907      1.911427e-03  2.008021e-03  2.109569e-03  2.216321e-03
## ASV5230     -5.062390e-03 -5.251269e-03 -5.445407e-03 -5.644837e-03
## ASV6509     -5.399318e-03 -5.600742e-03 -5.807772e-03 -6.020445e-03
## ASV7376     -3.862646e-03 -4.006725e-03 -4.154813e-03 -4.306936e-03
## ASV8163     -5.755250e-03 -5.969897e-03 -6.190514e-03 -6.417140e-03
## ASV8195     -5.059713e-03 -5.248395e-03 -5.442323e-03 -5.641532e-03
## ASV8923      1.746200e-03  1.833069e-03  1.924244e-03  2.019927e-03
## ASV9666     -2.544545e-03 -2.619411e-03 -2.694549e-03 -2.769784e-03
## ASV1482      2.886483e-03  3.022219e-03  3.164190e-03  3.312662e-03
## ASV2726      2.658271e-03  2.783773e-03  2.915058e-03  3.052374e-03
## ASV3281     -2.108135e-02 -2.186752e-02 -2.267555e-02 -2.350560e-02
## ASV4235     -2.107856e-02 -2.186452e-02 -2.267234e-02 -2.350216e-02
## ASV4808      4.504848e-03  4.696700e-03  4.895975e-03  5.102916e-03
## ASV4861     -1.099464e-02 -1.145876e-02 -1.194066e-02 -1.244090e-02
## ASV5276      6.421878e-03  6.694285e-03  6.977073e-03  7.270557e-03
## ASV5837      2.141426e-03  2.241039e-03  2.345216e-03  2.454161e-03
## ASV7098      3.068853e-03  3.210106e-03  3.357697e-03  3.511897e-03
## ASV8451     -3.586309e-03 -3.719925e-03 -3.857246e-03 -3.998298e-03
## ASV8694     -2.106190e-02 -2.184651e-02 -2.265287e-02 -2.348113e-02
## ASV0905     -9.988658e-04 -1.045886e-03 -1.094945e-03 -1.146107e-03
## ASV2900      4.985903e-03  5.186626e-03  5.394216e-03  5.608836e-03
## ASV3963     -5.033158e-03 -5.231007e-03 -5.435273e-03 -5.646083e-03
## ASV0041     -9.298688e-04 -9.734322e-04 -1.018982e-03 -1.066604e-03
## ASV1865      2.774884e-03  2.909212e-03  3.049985e-03  3.197498e-03
## ASV1140      1.548586e-03  1.621657e-03  1.698037e-03  1.777855e-03
## ASV1179      1.585426e-03  1.657631e-03  1.732959e-03  1.811529e-03
## ASV0279      2.395576e-03  2.501873e-03  2.612602e-03  2.727927e-03
## ASV0043     -4.377973e-04 -4.602273e-04 -4.838626e-04 -5.087715e-04
## ASV2097     -1.410224e-03 -1.469619e-03 -1.531292e-03 -1.595320e-03
## ASV0309     -2.809155e-04 -2.930368e-04 -3.056348e-04 -3.187251e-04
## ASV0607      3.783319e-03  3.957295e-03  4.138986e-03  4.328705e-03
## ASV0025     -1.054548e-03 -1.103414e-03 -1.154467e-03 -1.207797e-03
## ASV2284     -3.980461e-03 -4.142537e-03 -4.310276e-03 -4.483818e-03
## ASV0556      1.087400e-03  1.140686e-03  1.196584e-03  1.255217e-03
## ASV5040     -4.214809e-03 -4.486916e-03 -4.776894e-03 -5.085848e-03
## ASV2924     -1.267177e-02 -1.317246e-02 -1.368943e-02 -1.422300e-02
## ASV1331      3.338581e-03  3.489488e-03  3.646889e-03  3.811037e-03
## ASV0506     -1.405491e-03 -1.460436e-03 -1.517036e-03 -1.575299e-03
## ASV1514      5.057681e-03  5.286026e-03  5.524096e-03  5.772254e-03
## ASV2144      4.821440e-03  5.038777e-03  5.265412e-03  5.501703e-03
## ASV2265      3.176085e-03  3.319969e-03  3.470048e-03  3.626560e-03
## ASV5156      2.314990e-03  2.399020e-03  2.485082e-03  2.573151e-03
## ASV5534      6.855773e-04  7.072319e-04  7.290848e-04  7.510927e-04
## ASV5747     -1.100966e-03 -1.194916e-03 -1.296307e-03 -1.405655e-03
## ASV6657      2.427057e-03  2.529827e-03  2.636451e-03  2.747038e-03
## ASV0658     -1.783469e-03 -1.855013e-03 -1.928895e-03 -2.005150e-03
## ASV0716      3.255622e-03  3.395453e-03  3.540633e-03  3.691311e-03
## ASV1657      6.212851e-03  6.465976e-03  6.727719e-03  6.998245e-03
## ASV1885      5.145697e-03  5.337660e-03  5.534653e-03  5.736639e-03
## ASV2333      2.844851e-03  2.970538e-03  3.101373e-03  3.237535e-03
## ASV3375      2.180829e-03  2.271365e-03  2.365178e-03  2.462355e-03
## ASV4317      1.999448e-03  2.091241e-03  2.187149e-03  2.287353e-03
## ASV9599     -4.622963e-04 -5.017396e-04 -5.443057e-04 -5.902117e-04
## ASV0175     -3.076218e-03 -3.209796e-03 -3.348600e-03 -3.492784e-03
## ASV1032      1.280231e-03  1.332188e-03  1.385904e-03  1.441414e-03
## ASV1235      2.248397e-03  2.329910e-03  2.413290e-03  2.498489e-03
## ASV1262      3.182650e-03  3.323708e-03  3.470571e-03  3.623442e-03
## ASV1320      1.914286e-03  2.009408e-03  2.109328e-03  2.214288e-03
## ASV13797     1.831142e-03  1.910420e-03  1.992843e-03  2.078516e-03
## ASV1491      2.800238e-03  2.941004e-03  3.088841e-03  3.244081e-03
## ASV15014    -3.594374e-04 -3.900940e-04 -4.231763e-04 -4.588527e-04
## ASV1510      3.766577e-03  3.945583e-03  4.132894e-03  4.328861e-03
## ASV1551      1.257703e-02  1.314955e-02  1.374693e-02  1.437016e-02
## ASV1919      1.629323e-03  1.734113e-03  1.845774e-03  1.964729e-03
## ASV2114      2.259043e-03  2.353909e-03  2.452334e-03  2.554428e-03
## ASV21486    -3.085947e-04 -3.349033e-04 -3.632922e-04 -3.939057e-04
## ASV2448      2.352843e-03  2.454263e-03  2.559638e-03  2.669087e-03
## ASV2589      4.377536e-03  4.557256e-03  4.743278e-03  4.935747e-03
## ASV2608      2.992849e-03  3.123708e-03  3.259840e-03  3.401423e-03
## ASV2786      6.053580e-03  6.326756e-03  6.611807e-03  6.909228e-03
## ASV2827      2.110885e-03  2.201976e-03  2.296606e-03  2.394879e-03
## ASV2872      9.083383e-03  9.463941e-03  9.858252e-03  1.026663e-02
## ASV3125      1.771169e-03  1.845052e-03  1.921615e-03  2.000927e-03
## ASV3247      3.900601e-03  4.065354e-03  4.236234e-03  4.413404e-03
## ASV3451     -9.562367e-04 -1.037757e-03 -1.125724e-03 -1.220583e-03
## ASV3465     -6.697963e-06 -1.874380e-05 -3.223582e-05 -4.729616e-05
## ASV3809      5.236215e-03  5.455063e-03  5.681859e-03  5.916798e-03
## ASV4006      2.563274e-03  2.671862e-03  2.784500e-03  2.901295e-03
## ASV4046      3.765021e-03  3.924496e-03  4.089961e-03  4.261586e-03
## ASV4938      1.156068e-04  1.008813e-04  8.398927e-05  6.474350e-05
## ASV5435     -1.622256e-03 -1.760502e-03 -1.909672e-03 -2.070523e-03
## ASV5605      2.052294e-03  2.126146e-03  2.201647e-03  2.278747e-03
## ASV5635     -5.410592e-04 -5.871571e-04 -6.368964e-04 -6.905293e-04
## ASV5743      1.806107e-03  1.884111e-03  1.965180e-03  2.049410e-03
## ASV6627     -5.615167e-04 -6.093518e-04 -6.609649e-04 -7.166174e-04
## ASV6785     -6.250102e-04 -6.782459e-04 -7.356848e-04 -7.976181e-04
## ASV7368      2.282788e-03  2.386489e-03  2.494716e-03  2.607652e-03
## ASV9118      7.607568e-04  7.885427e-04  8.170252e-04  8.461991e-04
## ASV9135      1.377335e-03  1.423437e-03  1.470254e-03  1.517725e-03
## ASV9435      1.733330e-03  1.798993e-03  1.866445e-03  1.935676e-03
## ASV9671     -8.014221e-04 -8.696657e-04 -9.432954e-04 -1.022684e-03
## ASV0387     -3.124283e-03 -3.252306e-03 -3.384737e-03 -3.521661e-03
## ASV0454     -5.067107e-03 -5.280391e-03 -5.501500e-03 -5.730629e-03
## ASV0751     -1.406882e-03 -1.461244e-03 -1.517193e-03 -1.574735e-03
## ASV1081      3.143358e-03  3.283738e-03  3.429940e-03  3.582163e-03
## ASV1332      5.526201e-03  5.765854e-03  6.014878e-03  6.273553e-03
## ASV2659      6.211503e-03  6.490980e-03  6.782201e-03  7.085578e-03
## ASV2979      2.675609e-03  2.786609e-03  2.901534e-03  3.020467e-03
## ASV4184      3.722787e-03  3.864929e-03  4.011062e-03  4.161183e-03
## ASV6198      1.233193e-03  1.284787e-03  1.338319e-03  1.393849e-03
## ASV7454      1.311850e-03  1.365911e-03  1.421854e-03  1.479719e-03
## ASV8198      1.028505e-03  1.060665e-03  1.093067e-03  1.125638e-03
## ASV0855      3.386305e-03  3.538377e-03  3.696887e-03  3.862074e-03
## ASV10092     1.501765e-03  1.564511e-03  1.629553e-03  1.696951e-03
## ASV1532      3.073933e-03  3.217998e-03  3.368694e-03  3.526315e-03
## ASV2553      5.402799e-03  5.646140e-03  5.899847e-03  6.164311e-03
## ASV2741      7.535360e-03  7.889621e-03  8.260141e-03  8.647618e-03
## ASV4095      4.592631e-03  4.817222e-03  5.052642e-03  5.299372e-03
## ASV5295      1.483003e-03  1.540696e-03  1.600109e-03  1.661253e-03
## ASV5787     -3.294761e-04 -3.575162e-04 -3.877673e-04 -4.203821e-04
## ASV9455      2.049507e-03  2.137263e-03  2.228428e-03  2.323111e-03
## ASV10879     1.892357e-03  1.975548e-03  2.062155e-03  2.152303e-03
## ASV3997      2.547101e-03  2.669260e-03  2.797147e-03  2.931007e-03
## ASV6760      5.646360e-04  5.746624e-04  5.839082e-04  5.922589e-04
## ASV6990      1.905472e-03  1.984625e-03  2.066649e-03  2.151619e-03
## ASV9560      1.188580e-03  1.235131e-03  1.283147e-03  1.332653e-03
## ASV0220     -2.935015e-04 -3.065107e-04 -3.200568e-04 -3.341589e-04
## ASV2518      1.232246e-03  1.287847e-03  1.345822e-03  1.406260e-03
## ASV3615      3.075265e-03  3.210159e-03  3.350502e-03  3.496477e-03
## ASV0075     -1.318804e-05 -1.409338e-05 -1.505927e-05 -1.608930e-05
## ASV8070      9.497180e-05  9.341889e-05  9.134222e-05  8.868958e-05
## ASV1658      1.198777e-03  1.248794e-03  1.300628e-03  1.354328e-03
## ASV0773      2.225768e-03  2.320707e-03  2.419262e-03  2.521538e-03
## ASV0799      2.332470e-04  2.411587e-04  2.491713e-04  2.572677e-04
## ASV1839     -1.549276e-03 -1.616339e-03 -1.685993e-03 -1.758312e-03
## ASV0265      1.874418e-03  1.963225e-03  2.056179e-03  2.153464e-03
## ASV3741      6.330801e-04  6.581288e-04  6.839223e-04  7.104592e-04
## ASV0847      2.527103e-03  2.641423e-03  2.760651e-03  2.884974e-03
## ASV1026      3.287919e-03  3.433276e-03  3.584563e-03  3.741978e-03
## ASV1222     -8.036246e-04 -8.307527e-04 -8.583401e-04 -8.863559e-04
## ASV0729     -5.422282e-05 -5.677449e-05 -5.944569e-05 -6.224203e-05
## ASV0143     -8.149748e-04 -8.493861e-04 -8.850782e-04 -9.220861e-04
## ASV1328      4.407884e-04  4.642954e-04  4.891121e-04  5.153119e-04
## ASV9078     -1.023708e-03 -1.081422e-03 -1.142518e-03 -1.207194e-03
## ASV0027     -9.930105e-04 -1.038879e-03 -1.086786e-03 -1.136815e-03
## ASV0546     -1.104460e-03 -1.150239e-03 -1.197669e-03 -1.246793e-03
## ASV1136      2.748116e-03  2.871158e-03  2.999401e-03  3.133044e-03
## ASV3081      1.450638e-03  1.516588e-03  1.585440e-03  1.657317e-03
## ASV0531      4.660913e-04  4.910196e-04  5.173358e-04  5.451181e-04
## ASV2525      2.111823e-03  2.202213e-03  2.296067e-03  2.393486e-03
## ASV1083     -3.939919e-04 -4.076482e-04 -4.215753e-04 -4.357631e-04
## ASV0424     -3.111652e-04 -3.255797e-04 -3.406379e-04 -3.563658e-04
## ASV0644      2.313517e-04  2.510387e-04  2.722778e-04  2.951762e-04
## ASV6007     -2.320579e-04 -2.519292e-04 -2.733851e-04 -2.965375e-04
## ASV0564      1.043839e-03  1.093279e-03  1.145007e-03  1.199121e-03
## ASV1938      3.054611e-03  3.175259e-03  3.299662e-03  3.427858e-03
## ASV6516     -5.030153e-03 -5.259290e-03 -5.498430e-03 -5.747973e-03
## ASV0503     -1.914118e-03 -1.990957e-03 -2.070301e-03 -2.152186e-03
## ASV6913     -9.892089e-03 -1.032875e-02 -1.078354e-02 -1.125716e-02
## ASV0164     -1.254388e-03 -1.312469e-03 -1.373165e-03 -1.436586e-03
## ASV1576      3.508346e-03  3.664898e-03  3.828076e-03  3.998139e-03
## ASV1725      1.796038e-03  1.882843e-03  1.973775e-03  2.069017e-03
## ASV4501      8.607996e-04  8.912687e-04  9.223506e-04  9.540152e-04
## ASV10678    -4.624111e-03 -4.833306e-03 -5.051491e-03 -5.279012e-03
## ASV0944      7.498206e-04  7.858482e-04  8.236133e-04  8.631998e-04
## ASV2292      3.692186e-03  3.853081e-03  4.020367e-03  4.194248e-03
## ASV1090      1.492921e-03  1.558829e-03  1.627444e-03  1.698863e-03
## ASV9117     -9.605202e-04 -9.948097e-04 -1.029893e-03 -1.065756e-03
## ASV0285     -1.960722e-03 -2.065525e-03 -2.176097e-03 -2.292751e-03
## ASV0463     -1.018836e-03 -1.059990e-03 -1.102489e-03 -1.146352e-03
## ASV3199      1.284870e-03  1.335902e-03  1.388553e-03  1.442845e-03
## ASV0150     -2.356440e-04 -2.486269e-04 -2.623452e-04 -2.768393e-04
## ASV6583     -1.070816e-03 -1.113101e-03 -1.156819e-03 -1.202012e-03
## ASV0392      1.041928e-04  1.078982e-04  1.116775e-04  1.155269e-04
## ASV14007    -1.654958e-03 -1.726700e-03 -1.801241e-03 -1.878663e-03
## ASV0177     -7.744810e-04 -8.075903e-04 -8.419575e-04 -8.776176e-04
## ASV6448     -1.318749e-03 -1.388516e-03 -1.462078e-03 -1.539639e-03
## ASV5399     -7.776599e-03 -8.158825e-03 -8.559900e-03 -8.980726e-03
## ASV0277     -1.694640e-04 -1.764090e-04 -1.835751e-04 -1.909623e-04
## ASV2599      6.523233e-04  6.496772e-04  6.444844e-04  6.364878e-04
## ASV13465    -4.720974e-04 -4.852703e-04 -4.983998e-04 -5.114445e-04
## ASV2412      4.386300e-04  4.586074e-04  4.794559e-04  5.012104e-04
## ASV0423     -1.313525e-04 -1.342333e-04 -1.369637e-04 -1.395138e-04
## ASV5187      2.081299e-03  2.154778e-03  2.229857e-03  2.306491e-03
## ASV0701     -1.502902e-03 -1.572137e-03 -1.644455e-03 -1.719983e-03
## ASV4248      8.506301e-04  8.933855e-04  9.383062e-04  9.854981e-04
## ASV0519      1.432789e-03  1.500128e-03  1.570551e-03  1.644190e-03
## ASV0764      3.821228e-04  4.004007e-04  4.195336e-04  4.395581e-04
## ASV5385     -1.274053e-03 -1.333552e-03 -1.395781e-03 -1.460862e-03
## ASV3021     -2.004526e-03 -2.080073e-03 -2.157761e-03 -2.237603e-03
## ASV4119     -5.529727e-03 -5.777143e-03 -6.035144e-03 -6.304159e-03
## ASV2534     -2.870744e-04 -3.058898e-04 -3.259557e-04 -3.473505e-04
## ASV1061      1.480124e-03  1.555427e-03  1.634687e-03  1.718114e-03
## ASV0670     -3.784680e-04 -3.956978e-04 -4.136729e-04 -4.324217e-04
## ASV1384      1.706974e-03  1.791665e-03  1.880544e-03  1.973806e-03
## ASV1981      4.019995e-03  4.208271e-03  4.405159e-03  4.611030e-03
## ASV9632     -6.950748e-04 -7.137508e-04 -7.323092e-04 -7.506899e-04
## ASV4564      1.168338e-03  1.221412e-03  1.276762e-03  1.334471e-03
## ASV5289     -7.618274e-04 -7.999990e-04 -8.401510e-04 -8.823905e-04
## ASV0516      2.759039e-03  2.883675e-03  3.013621e-03  3.149073e-03
## ASV1463     -3.864597e-03 -4.038747e-03 -4.220327e-03 -4.409622e-03
## ASV0969      1.397546e-04  1.449724e-04  1.503124e-04  1.557700e-04
## ASV1113     -8.860967e-04 -9.264851e-04 -9.686352e-04 -1.012617e-03
## ASV1234     -1.158009e-03 -1.221387e-03 -1.288483e-03 -1.359531e-03
## ASV3814     -8.093410e-04 -8.643245e-04 -9.230624e-04 -9.857933e-04
## ASV1000      1.739636e-03  1.815125e-03  1.893560e-03  1.975028e-03
## ASV0079     -2.091868e-04 -2.207226e-04 -2.329289e-04 -2.458457e-04
## ASV0145      2.888138e-04  2.979178e-04  3.071204e-04  3.164069e-04
## ASV0457     -2.275458e-03 -2.375553e-03 -2.479699e-03 -2.588032e-03
## ASV1485      1.901553e-04  1.995567e-04  2.094350e-04  2.198150e-04
## ASV0535      7.453738e-04  7.842207e-04  8.251369e-04  8.682303e-04
## ASV0259     -1.277895e-03 -1.334956e-03 -1.394381e-03 -1.456252e-03
## ASV0570      4.141499e-04  4.352527e-04  4.574666e-04  4.808515e-04
## ASV0906      1.446130e-03  1.508379e-03  1.573028e-03  1.640146e-03
## ASV1748      1.209306e-03  1.238926e-03  1.267715e-03  1.295472e-03
## ASV5520     -2.066686e-03 -2.174445e-03 -2.287945e-03 -2.407483e-03
## ASV2288     -4.853299e-03 -5.073151e-03 -5.302474e-03 -5.541634e-03
## ASV1887     -1.108158e-03 -1.170750e-03 -1.236904e-03 -1.306805e-03
## ASV0374     -1.856670e-04 -1.920214e-04 -1.984900e-04 -2.050664e-04
## ASV0823      2.768480e-03  2.886193e-03  3.008382e-03  3.135178e-03
## ASV0717      2.126962e-04  2.224489e-04  2.326282e-04  2.432507e-04
## ASV0431     -5.846735e-04 -6.122624e-04 -6.411362e-04 -6.713528e-04
## ASV1030      6.707112e-03  7.022919e-03  7.353346e-03  7.699043e-03
## ASV1082     -8.673833e-04 -9.074604e-04 -9.493287e-04 -9.930625e-04
## ASV2684      1.875740e-04  2.017447e-04  2.168865e-04  2.330520e-04
## ASV0051      8.260240e-04  8.641152e-04  9.039129e-04  9.454895e-04
## ASV0513     -2.488780e-04 -2.590440e-04 -2.695459e-04 -2.803873e-04
## ASV0581      1.502022e-03  1.570566e-03  1.642089e-03  1.716706e-03
## ASV7282      5.418497e-04  5.733489e-04  6.068146e-04  6.423756e-04
## ASV3009     -1.283499e-03 -1.341909e-03 -1.402853e-03 -1.466430e-03
## ASV2106      1.646552e-03  1.735874e-03  1.830247e-03  1.929960e-03
## ASV1012      1.098404e-03  1.149925e-03  1.203780e-03  1.260062e-03
## ASV0921      1.122380e-03  1.176852e-03  1.234003e-03  1.293966e-03
## ASV0010     -6.463446e-04 -6.762328e-04 -7.074544e-04 -7.400640e-04
## ASV1178      2.987834e-04  3.131151e-04  3.281096e-04  3.437932e-04
## ASV2848     -1.696835e-03 -1.771610e-03 -1.849487e-03 -1.930584e-03
## ASV0586      4.337310e-03  4.542324e-03  4.756949e-03  4.981629e-03
## ASV4225     -5.650109e-03 -5.827540e-03 -6.006981e-03 -6.188174e-03
## ASV2156     -2.424277e-03 -2.537245e-03 -2.655358e-03 -2.778838e-03
## ASV9778     -1.731707e-03 -1.811197e-03 -1.894204e-03 -1.980874e-03
## ASV0493     -3.483275e-03 -3.636933e-03 -3.796906e-03 -3.963418e-03
## ASV3770     -5.160478e-04 -5.494679e-04 -5.850883e-04 -6.230454e-04
## ASV0470      2.470006e-03  2.583322e-03  2.701654e-03  2.825209e-03
## ASV0262     -1.108694e-03 -1.165769e-03 -1.225854e-03 -1.289109e-03
## ASV0998      6.495584e-04  6.799923e-04  7.118283e-04  7.451290e-04
## ASV7708     -2.960920e-04 -3.077775e-04 -3.198082e-04 -3.321832e-04
## ASV0453     -2.525956e-04 -2.641141e-04 -2.761546e-04 -2.887419e-04
## ASV0044      1.027999e-03  1.074447e-03  1.122883e-03  1.173381e-03
## ASV5490      5.636241e-04  5.859699e-04  6.089670e-04  6.326096e-04
## ASV2638     -3.231152e-04 -3.357541e-04 -3.488418e-04 -3.623977e-04
## ASV0829      3.539963e-03  3.698466e-03  3.863464e-03  4.035160e-03
## ASV0601      1.206671e-03  1.264267e-03  1.324595e-03  1.387784e-03
## ASV0234      9.602354e-05  1.011037e-04  1.064708e-04  1.121422e-04
## ASV0133      1.810424e-03  1.893488e-03  1.980218e-03  2.070764e-03
## ASV0323      6.078112e-04  6.373783e-04  6.684062e-04  7.009684e-04
## ASV0854     -4.084879e-04 -4.268529e-04 -4.459976e-04 -4.659513e-04
## ASV0110      1.144539e-03  1.197506e-03  1.252855e-03  1.310688e-03
## ASV0816     -1.146441e-04 -1.200952e-04 -1.258019e-04 -1.317754e-04
## ASV1031     -4.084612e-04 -4.253889e-04 -4.429358e-04 -4.611200e-04
## ASV0144     -5.344433e-04 -5.599783e-04 -5.867405e-04 -6.147893e-04
## ASV0020     -2.543409e-04 -2.671715e-04 -2.806778e-04 -2.948974e-04
## ASV0962     -6.733754e-04 -7.037167e-04 -7.353440e-04 -7.683041e-04
## ASV0794      1.306121e-03  1.370619e-03  1.438307e-03  1.509336e-03
## ASV7117     -1.168284e-03 -1.219990e-03 -1.273819e-03 -1.329847e-03
## ASV1008     -5.821439e-04 -6.101893e-04 -6.395908e-04 -6.704139e-04
## ASV0096      1.464333e-03  1.531995e-03  1.602689e-03  1.676544e-03
## ASV0128     -2.445112e-03 -2.561894e-03 -2.684254e-03 -2.812459e-03
## ASV5232      2.270212e-03  2.380636e-03  2.496439e-03  2.617877e-03
## ASV0031     -1.733135e-04 -1.814528e-04 -1.899651e-04 -1.988665e-04
## ASV1744     -2.361349e-03 -2.473012e-03 -2.589987e-03 -2.712533e-03
## ASV0289      6.590832e-04  6.894481e-04  7.211724e-04  7.543138e-04
## ASV7413     -4.317181e-04 -4.577817e-04 -4.854875e-04 -5.149371e-04
## ASV0822     -2.857120e-03 -2.981746e-03 -3.111330e-03 -3.246029e-03
## ASV8111     -4.726793e-03 -4.934232e-03 -5.150203e-03 -5.375024e-03
## ASV0687      6.355125e-04  6.657777e-04  6.974620e-04  7.306284e-04
## ASV0112     -2.328320e-04 -2.440431e-04 -2.557938e-04 -2.681096e-04
## ASV0987      7.880519e-04  8.259918e-04  8.657690e-04  9.074723e-04
## ASV5332     -4.150323e-04 -4.270234e-04 -4.391268e-04 -4.513342e-04
## ASV1129     -1.424634e-03 -1.490597e-03 -1.559544e-03 -1.631602e-03
## ASV1274     -3.917938e-04 -4.096629e-04 -4.283139e-04 -4.477786e-04
## ASV0119      9.489317e-04  9.926941e-04  1.038411e-03  1.086165e-03
## ASV0890     -5.320499e-05 -5.609418e-05 -5.916228e-05 -6.242249e-05
## ASV0848     -1.761880e-03 -1.843120e-03 -1.927993e-03 -2.016652e-03
## ASV5944     -7.674977e-03 -8.020153e-03 -8.379990e-03 -8.755038e-03
## ASV19741    -2.806620e-03 -2.933812e-03 -3.066495e-03 -3.204884e-03
## ASV0504     -3.492412e-03 -3.645362e-03 -3.804488e-03 -3.969999e-03
## ASV2146     -2.492792e-03 -2.598735e-03 -2.708740e-03 -2.822932e-03
## ASV0089     -5.988104e-04 -6.260320e-04 -6.544279e-04 -6.840426e-04
## ASV2301     -9.810861e-04 -1.026921e-03 -1.074852e-03 -1.124970e-03
## ASV2982     -1.567876e-02 -1.624974e-02 -1.683542e-02 -1.743580e-02
## ASV0891     -1.135280e-03 -1.187136e-03 -1.241263e-03 -1.297752e-03
## ASV0093      1.235561e-03  1.291431e-03  1.349703e-03  1.410469e-03
## ASV0042      4.365036e-04  4.566678e-04  4.777373e-04  4.997505e-04
## ASV0980      1.366446e-03  1.423982e-03  1.483598e-03  1.545339e-03
## ASV0069     -6.659449e-04 -6.966077e-04 -7.286302e-04 -7.620679e-04
## ASV1364     -5.046438e-04 -5.271480e-04 -5.505878e-04 -5.749965e-04
## ASV0524     -2.581975e-03 -2.703295e-03 -2.830232e-03 -2.963037e-03
## ASV0435      3.522738e-03  3.686533e-03  3.857761e-03  4.036743e-03
## ASV0517     -6.938574e-04 -7.259575e-04 -7.595011e-04 -7.945496e-04
## ASV3167     -5.231958e-03 -5.498606e-03 -5.779138e-03 -6.074274e-03
## ASV4280     -3.160573e-03 -3.305382e-03 -3.456592e-03 -3.614470e-03
## ASV1158      1.173063e-03  1.231933e-03  1.293719e-03  1.358552e-03
## ASV2214      1.035821e-03  1.081159e-03  1.128413e-03  1.177667e-03
## ASV0544     -1.744319e-03 -1.827336e-03 -1.914290e-03 -2.005364e-03
## ASV5326     -2.465512e-04 -2.586583e-04 -2.713766e-04 -2.847383e-04
## ASV3765     -1.334696e-03 -1.395434e-03 -1.458806e-03 -1.524915e-03
## ASV4646     -4.802624e-05 -5.666313e-05 -6.616830e-05 -7.660906e-05
## ASV0090      9.703170e-05  1.006348e-04  1.043215e-04  1.080886e-04
## ASV3680      2.135985e-03  2.224969e-03  2.317112e-03  2.412480e-03
## ASV0111      2.271927e-04  2.369869e-04  2.471588e-04  2.577194e-04
## ASV0768      3.417446e-04  3.584462e-04  3.759799e-04  3.943884e-04
## ASV4862     -1.650205e-04 -1.695180e-04 -1.739266e-04 -1.782157e-04
## ASV1742     -1.921849e-03 -2.006875e-03 -2.095427e-03 -2.187634e-03
## ASV3701     -6.751013e-04 -7.006357e-04 -7.268962e-04 -7.538864e-04
## ASV2386     -3.748783e-03 -3.924490e-03 -4.108217e-03 -4.300305e-03
## ASV0375     -2.594243e-03 -2.709775e-03 -2.830164e-03 -2.955594e-03
## ASV2796      8.701439e-04  9.062276e-04  9.436426e-04  9.824301e-04
## ASV1369      1.980876e-03  2.066649e-03  2.155952e-03  2.248927e-03
## ASV10272    -2.954994e-03 -3.088698e-03 -3.228119e-03 -3.373469e-03
## ASV10354    -4.400181e-03 -4.599242e-03 -4.806810e-03 -5.023202e-03
## ASV1067      1.433617e-03  1.497691e-03  1.564461e-03  1.634025e-03
## ASV1900      2.390590e-03  2.501664e-03  2.617769e-03  2.739121e-03
## ASV4079     -1.128066e-03 -1.184560e-03 -1.243924e-03 -1.306300e-03
## ASV4149      4.529953e-03  4.721720e-03  4.920583e-03  5.126720e-03
## ASV5140     -4.399678e-03 -4.598691e-03 -4.806205e-03 -5.022539e-03
## ASV10782     1.987609e-04  2.133507e-04  2.291004e-04  2.461054e-04
## ASV4273     -3.768369e-04 -3.889518e-04 -4.011090e-04 -4.132635e-04
## ASV8121      1.991256e-03  2.082665e-03  2.178139e-03  2.277848e-03
## ASV8438     -5.005238e-03 -5.231619e-03 -5.467671e-03 -5.713752e-03
## ASV9390     -5.004412e-03 -5.230717e-03 -5.466686e-03 -5.712676e-03
## ASV1340      4.078320e-03  4.267699e-03  4.465632e-03  4.672484e-03
## ASV2650     -9.263331e-03 -9.678053e-03 -1.011012e-02 -1.056016e-02
## ASV4674      2.474037e-03  2.584975e-03  2.700571e-03  2.820990e-03
## ASV10492     2.268454e-05  2.175347e-05  2.060063e-05  1.920070e-05
## ASV11430    -3.818460e-03 -3.991097e-03 -4.171101e-03 -4.358748e-03
## ASV12135    -3.817831e-03 -3.990409e-03 -4.170350e-03 -4.357927e-03
## ASV14970    -4.694498e-03 -4.906668e-03 -5.127887e-03 -5.358490e-03
## ASV1954      5.716820e-03  5.976752e-03  6.247932e-03  6.530795e-03
## ASV2613      3.601375e-03  3.763628e-03  3.932781e-03  4.109093e-03
## ASV2757      2.184806e-03  2.277707e-03  2.374091e-03  2.474050e-03
## ASV2909     -6.829919e-03 -7.151701e-03 -7.488460e-03 -7.840875e-03
## ASV2954     -2.535999e-04 -2.651527e-04 -2.772012e-04 -2.897634e-04
## ASV2969      1.738203e-03  1.819230e-03  1.903952e-03  1.992528e-03
## ASV3410      6.236810e-04  6.536532e-04  6.850809e-04  7.180364e-04
## ASV3575      1.152746e-03  1.203868e-03  1.257115e-03  1.312568e-03
## ASV4275      2.925605e-03  3.051762e-03  3.182784e-03  3.318809e-03
## ASV4652      6.554727e-04  6.865618e-04  7.191155e-04  7.532014e-04
## ASV4761      2.116630e-03  2.207378e-03  2.301560e-03  2.399266e-03
## ASV6003      1.630101e-03  1.708775e-03  1.791283e-03  1.877813e-03
## ASV6110     -1.077380e-02 -1.126090e-02 -1.176879e-02 -1.229824e-02
## ASV7427      1.852326e-03  1.934096e-03  2.019199e-03  2.107745e-03
## ASV8092     -3.532766e-03 -3.692469e-03 -3.858986e-03 -4.032571e-03
## ASV8169     -1.077085e-02 -1.125767e-02 -1.176526e-02 -1.229439e-02
## ASV9693      1.821887e-03  1.903621e-03  1.988786e-03  2.077505e-03
## ASV10913     1.245034e-03  1.303211e-03  1.364053e-03  1.427675e-03
## ASV1979      1.070772e-03  1.117554e-03  1.166181e-03  1.216707e-03
## ASV3772      2.211742e-03  2.308555e-03  2.409251e-03  2.513959e-03
## ASV0113     -3.049809e-04 -3.191820e-04 -3.340249e-04 -3.495364e-04
## ASV1800     -4.043259e-04 -4.232443e-04 -4.430143e-04 -4.636698e-04
## ASV2335     -8.215403e-03 -8.582094e-03 -8.964326e-03 -9.362706e-03
## ASV0692     -5.869705e-05 -6.167721e-05 -6.482050e-05 -6.813709e-05
## ASV1120      3.051750e-04  3.197014e-04  3.349196e-04  3.508625e-04
## ASV1434     -1.497193e-03 -1.566381e-03 -1.638673e-03 -1.714198e-03
## ASV0076     -7.001063e-04 -7.322787e-04 -7.658721e-04 -8.009439e-04
## ASV0361      2.510954e-03  2.627636e-03  2.749610e-03  2.877103e-03
## ASV2231     -8.412430e-04 -8.838081e-04 -9.286042e-04 -9.757518e-04
## ASV2018     -2.009849e-04 -2.102627e-04 -2.199590e-04 -2.300920e-04
## ASV1529      1.100038e-03  1.152458e-03  1.207373e-03  1.264898e-03
## ASV0841     -3.752435e-04 -3.922158e-04 -4.099167e-04 -4.283741e-04
## ASV2556     -6.926154e-03 -7.243532e-03 -7.574867e-03 -7.920722e-03
## ASV2777      2.188508e-03  2.277804e-03  2.370091e-03  2.465414e-03
## ASV0355      1.723069e-03  1.801802e-03  1.883990e-03  1.969774e-03
## ASV5169     -2.054942e-03 -2.148121e-03 -2.245304e-03 -2.346644e-03
## ASV3091      1.966058e-03  2.058501e-03  2.155234e-03  2.256453e-03
## ASV2435      7.805521e-04  8.157149e-04  8.523675e-04  8.905644e-04
## ASV6822     -4.231771e-03 -4.423176e-03 -4.622759e-03 -4.830824e-03
## ASV12605    -4.161618e-03 -4.354355e-03 -4.555755e-03 -4.766184e-03
## ASV0286     -9.926430e-04 -1.038034e-03 -1.085445e-03 -1.134960e-03
## ASV0074     -3.961272e-04 -4.145843e-04 -4.338783e-04 -4.540447e-04
## ASV2485     -1.849451e-04 -1.956875e-04 -2.071328e-04 -2.193325e-04
## ASV1233     -3.129240e-03 -3.274746e-03 -3.426872e-03 -3.585908e-03
## ASV0356     -8.151605e-04 -8.516341e-04 -8.896558e-04 -9.292855e-04
## ASV2918     -3.447655e-03 -3.603874e-03 -3.766833e-03 -3.936795e-03
## ASV1427     -4.481793e-04 -4.703149e-04 -4.935797e-04 -5.180346e-04
## ASV1409      7.774752e-04  8.145460e-04  8.533817e-04  8.940654e-04
## ASV0770      2.320909e-04  2.418733e-04  2.520082e-04  2.625027e-04
## ASV1403     -2.129534e-03 -2.226658e-03 -2.328020e-03 -2.433788e-03
## ASV0314     -7.269947e-04 -7.588641e-04 -7.919951e-04 -8.264245e-04
## ASV0187     -2.212118e-04 -2.317259e-04 -2.427260e-04 -2.542327e-04
## ASV0313     -1.039925e-03 -1.086345e-03 -1.134695e-03 -1.185042e-03
## ASV1087      2.421107e-03  2.531932e-03  2.647633e-03  2.768408e-03
## ASV1970     -3.663240e-04 -3.828679e-04 -4.001131e-04 -4.180845e-04
## ASV0754      2.674364e-03  2.797814e-03  2.926788e-03  3.061518e-03
## ASV3775     -6.429267e-04 -6.730087e-04 -7.044730e-04 -7.373810e-04
## ASV0132     -4.603231e-04 -4.814788e-04 -5.035728e-04 -5.266436e-04
## ASV2329      1.797641e-04  1.804045e-04  1.804925e-04  1.799668e-04
## ASV0561      6.577503e-04  6.855127e-04  7.142660e-04  7.440273e-04
## ASV0130     -1.392893e-03 -1.457084e-03 -1.524128e-03 -1.594143e-03
## ASV0226      1.745701e-03  1.825101e-03  1.907939e-03  1.994347e-03
## ASV12648    -2.426640e-03 -2.535012e-03 -2.647982e-03 -2.765731e-03
## ASV0204      1.680195e-03  1.756643e-03  1.836403e-03  1.919605e-03
## ASV0767     -8.423318e-04 -8.837943e-04 -9.273534e-04 -9.731196e-04
## ASV0335     -1.560549e-03 -1.631110e-03 -1.704682e-03 -1.781376e-03
## ASV5901     -3.329314e-04 -3.471351e-04 -3.618959e-04 -3.772331e-04
## ASV0596      1.806110e-05  2.089840e-05  2.404246e-05  2.752178e-05
## ASV9271      1.335107e-03  1.403154e-03  1.474711e-03  1.549955e-03
## ASV0904      1.030225e-03  1.078934e-03  1.129923e-03  1.183298e-03
## ASV15270    -7.102020e-04 -7.472649e-04 -7.862812e-04 -8.273479e-04
## ASV0990     -5.670424e-04 -5.936050e-04 -6.213912e-04 -6.504558e-04
## ASV0155     -1.165376e-03 -1.218675e-03 -1.274308e-03 -1.332369e-03
## ASV0086     -2.329893e-04 -2.437017e-04 -2.548889e-04 -2.665702e-04
## ASV2581     -1.060492e-04 -1.101850e-04 -1.144301e-04 -1.187814e-04
## ASV1579     -9.692441e-04 -1.015346e-03 -1.063629e-03 -1.114194e-03
## ASV7730     -8.326993e-05 -8.989097e-05 -9.696905e-05 -1.045267e-04
## ASV0897      1.475942e-04  1.548663e-04  1.625038e-04  1.705254e-04
## ASV1975      6.533950e-03  6.833971e-03  7.147299e-03  7.474487e-03
##                                                                    
## (Intercept)  2.429653e-02  2.540237e-02  2.655589e-02  2.775890e-02
## ASV1236      3.827597e-03  3.992616e-03  4.163986e-03  4.341887e-03
## ASV0421     -1.798293e-03 -1.874674e-03 -1.953894e-03 -2.036021e-03
## ASV0691     -3.577537e-03 -3.719726e-03 -3.866368e-03 -4.017505e-03
## ASV0899      2.304079e-03  2.410022e-03  2.520596e-03  2.635976e-03
## ASV1004      8.650302e-03  9.025852e-03  9.416087e-03  9.821443e-03
## ASV1041     -5.321857e-03 -5.555702e-03 -5.798898e-03 -6.051736e-03
## ASV1058      5.393027e-03  5.627580e-03  5.871368e-03  6.124673e-03
## ASV12542     2.007089e-03  2.091977e-03  2.180016e-03  2.271289e-03
## ASV1294      4.551625e-03  4.750945e-03  4.958225e-03  5.173718e-03
## ASV13113     1.691602e-03  1.772771e-03  1.857858e-03  1.947056e-03
## ASV1318      4.976229e-03  5.193337e-03  5.419031e-03  5.653575e-03
## ASV2269     -8.493342e-03 -8.866659e-03 -9.254827e-03 -9.658292e-03
## ASV2542      3.831263e-03  4.008327e-03  4.193318e-03  4.386566e-03
## ASV2660     -3.749587e-03 -3.911990e-03 -4.080687e-03 -4.255857e-03
## ASV2737      6.492202e-04  6.735258e-04  6.984810e-04  7.240835e-04
## ASV2840      4.660415e-03  4.858093e-03  5.063075e-03  5.275540e-03
## ASV3053      3.952845e-02  4.123078e-02  4.299875e-02  4.483423e-02
## ASV3077      1.390287e-03  1.450057e-03  1.512140e-03  1.576606e-03
## ASV3134      2.783534e-03  2.914460e-03  3.051472e-03  3.194846e-03
## ASV3140      3.337025e-03  3.488427e-03  3.646301e-03  3.810888e-03
## ASV3579      1.128398e-03  1.183473e-03  1.241284e-03  1.301969e-03
## ASV6119     -2.317783e-03 -2.419635e-03 -2.525536e-03 -2.635608e-03
## ASV7557     -4.714309e-03 -4.921431e-03 -5.136783e-03 -5.360615e-03
## ASV8422      1.003637e-03  1.044877e-03  1.087566e-03  1.131737e-03
## ASV1086     -2.358266e-04 -2.452513e-04 -2.549948e-04 -2.650647e-04
## ASV1310      1.996660e-03  2.083319e-03  2.173367e-03  2.266904e-03
## ASV15750    -3.387434e-04 -3.529589e-04 -3.676640e-04 -3.828650e-04
## ASV16905    -9.677990e-04 -1.010317e-03 -1.054524e-03 -1.100472e-03
## ASV2033      4.337109e-03  4.535831e-03  4.743296e-03  4.959853e-03
## ASV2089      1.773144e-03  1.851345e-03  1.932671e-03  2.017219e-03
## ASV2127      6.643963e-03  6.932178e-03  7.231664e-03  7.542759e-03
## ASV2725      5.276419e-03  5.500762e-03  5.733485e-03  5.974804e-03
## ASV2804     -2.004255e-03 -2.092300e-03 -2.183844e-03 -2.278992e-03
## ASV3075      4.491930e-03  4.689868e-03  4.895891e-03  5.110280e-03
## ASV3327      6.231557e-03  6.516406e-03  6.813761e-03  7.124125e-03
## ASV3342      5.112524e-03  5.343795e-03  5.584942e-03  5.836333e-03
## ASV3532     -5.829788e-03 -6.094579e-03 -6.370763e-03 -6.658774e-03
## ASV3600      2.607770e-03  2.724420e-03  2.845973e-03  2.972610e-03
## ASV4013      4.996237e-03  5.215329e-03  5.443206e-03  5.680150e-03
## ASV4136      5.426949e-03  5.658109e-03  5.897937e-03  6.146663e-03
## ASV4195      2.025656e-02  2.114621e-02  2.207119e-02  2.303256e-02
## ASV4407     -7.922694e-03 -8.270581e-03 -8.632279e-03 -9.008200e-03
## ASV4717      6.958866e-04  7.193085e-04  7.431355e-04  7.673443e-04
## ASV6794      3.005027e-03  3.127461e-03  3.254066e-03  3.384925e-03
## ASV8324     -4.058258e-03 -4.236445e-03 -4.421704e-03 -4.614247e-03
## ASV8981     -1.268649e-04 -1.309534e-04 -1.350549e-04 -1.391542e-04
## ASV9859      1.315845e-03  1.382281e-03  1.452227e-03  1.525879e-03
## ASV0936      3.473664e-04  3.653750e-04  3.843087e-04  4.042110e-04
## ASV12683    -1.145892e-04 -1.209937e-04 -1.277449e-04 -1.348587e-04
## ASV1293      2.531855e-03  2.641225e-03  2.754824e-03  2.872773e-03
## ASV13055    -1.255504e-04 -1.296283e-04 -1.337076e-04 -1.377702e-04
## ASV17063    -2.103178e-03 -2.195479e-03 -2.291439e-03 -2.391168e-03
## ASV2228      1.712057e-03  1.787178e-03  1.865276e-03  1.946440e-03
## ASV2769      1.807733e-04  1.897683e-04  1.992337e-04  2.091953e-04
## ASV2803      1.472022e-03  1.531848e-03  1.593694e-03  1.657597e-03
## ASV2896      1.445018e-03  1.510792e-03  1.579458e-03  1.651139e-03
## ASV3062      1.585717e-03  1.660912e-03  1.739660e-03  1.822126e-03
## ASV3107      2.898878e-03  3.030959e-03  3.168810e-03  3.312663e-03
## ASV3265      3.907331e-03  4.076198e-03  4.251612e-03  4.433764e-03
## ASV3666      1.045303e-05  1.064254e-05  1.083285e-05  1.102477e-05
## ASV4497      1.195197e-03  1.247588e-03  1.302096e-03  1.358794e-03
## ASV6914     -3.042197e-04 -3.193055e-04 -3.351312e-04 -3.517306e-04
## ASV0576     -4.924523e-03 -5.127400e-03 -5.337311e-03 -5.554393e-03
## ASV0673      3.801971e-03  3.973611e-03  4.152553e-03  4.339067e-03
## ASV0772      2.170469e-03  2.266174e-03  2.365792e-03  2.469459e-03
## ASV0862     -3.048532e-04 -3.136779e-04 -3.224783e-04 -3.312223e-04
## ASV0898      1.625171e-03  1.701097e-03  1.780467e-03  1.863427e-03
## ASV0910      1.990663e-03  2.082149e-03  2.177690e-03  2.277452e-03
## ASV0964     -1.989296e-03 -2.074124e-03 -2.162167e-03 -2.253513e-03
## ASV10059     1.438469e-03  1.507477e-03  1.579823e-03  1.655673e-03
## ASV10263    -3.205784e-03 -3.346627e-03 -3.493069e-03 -3.645280e-03
## ASV1088      3.195302e-03  3.341742e-03  3.494690e-03  3.654422e-03
## ASV1101      3.707141e-03  3.868196e-03  4.035554e-03  4.209402e-03
## ASV1183      1.148686e-03  1.200886e-03  1.255330e-03  1.312101e-03
## ASV11956     9.430318e-04  9.793465e-04  1.016727e-03  1.055181e-03
## ASV12774    -3.863214e-05 -4.246480e-05 -4.662389e-05 -5.113366e-05
## ASV1321      4.965483e-03  5.194364e-03  5.433454e-03  5.683177e-03
## ASV13793    -2.209165e-03 -2.306205e-03 -2.407101e-03 -2.511970e-03
## ASV14482     1.345035e-06 -7.708903e-07 -3.129683e-06 -5.749230e-06
## ASV15483     8.311435e-04  8.692212e-04  9.089926e-04  9.505291e-04
## ASV2062      4.093856e-03  4.274883e-03  4.463305e-03  4.659375e-03
## ASV2132      3.617943e-03  3.784023e-03  3.957464e-03  4.138568e-03
## ASV2413      3.194723e-03  3.332726e-03  3.476096e-03  3.624993e-03
## ASV2490      9.785735e-03  1.019508e-02  1.061910e-02  1.105813e-02
## ASV2594      1.164617e-03  1.216412e-03  1.270389e-03  1.326634e-03
## ASV2822     -5.839814e-03 -6.096442e-03 -6.363279e-03 -6.640633e-03
## ASV2863      6.249536e-03  6.516760e-03  6.794081e-03  7.081771e-03
## ASV2910      2.167972e-03  2.260869e-03  2.357308e-03  2.457389e-03
## ASV2980      2.130752e-03  2.225092e-03  2.323258e-03  2.425371e-03
## ASV3307      4.624589e-03  4.827738e-03  5.038962e-03  5.258503e-03
## ASV3474      2.868015e-03  3.001227e-03  3.140473e-03  3.286010e-03
## ASV3502      3.411806e-03  3.564637e-03  3.723899e-03  3.889829e-03
## ASV4236      4.865717e-03  5.073328e-03  5.288753e-03  5.512198e-03
## ASV4842     -1.003604e-03 -1.051638e-03 -1.101867e-03 -1.154374e-03
## ASV4894     -2.209721e-03 -2.306816e-03 -2.407773e-03 -2.512708e-03
## ASV5290      1.769173e-03  1.848702e-03  1.931614e-03  2.018038e-03
## ASV5501      8.818752e-04  9.214649e-04  9.627665e-04  1.005851e-03
## ASV5795      1.083347e-03  1.132246e-03  1.183246e-03  1.236430e-03
## ASV5987     -6.183048e-03 -6.454775e-03 -6.737313e-03 -7.030991e-03
## ASV6267     -6.968532e-03 -7.274717e-03 -7.593079e-03 -7.923987e-03
## ASV6862      2.793013e-03  2.909511e-03  3.030183e-03  3.155125e-03
## ASV7145      1.018293e-03  1.057610e-03  1.098100e-03  1.139774e-03
## ASV7673     -2.209458e-03 -2.306530e-03 -2.407461e-03 -2.512369e-03
## ASV7789      9.696114e-04  1.016930e-03  1.066607e-03  1.118763e-03
## ASV7809     -3.155442e-05 -3.156488e-05 -3.143177e-05 -3.113570e-05
## ASV8002     -2.791022e-03 -2.913639e-03 -3.041131e-03 -3.173647e-03
## ASV8205      9.381546e-04  9.794735e-04  1.022502e-03  1.067302e-03
## ASV9155     -7.630115e-04 -7.959684e-04 -8.301727e-04 -8.656550e-04
## ASV9221      6.450092e-05  6.696920e-05  6.951603e-05  7.214259e-05
## ASV9311     -4.480013e-03 -4.676794e-03 -4.881396e-03 -5.094055e-03
## ASV9557     -3.059452e-03 -3.193808e-03 -3.333503e-03 -3.478696e-03
## ASV9936     -6.177404e-03 -6.448632e-03 -6.730631e-03 -7.023725e-03
## ASV1445      4.085968e-03  4.270244e-03  4.462384e-03  4.662684e-03
## ASV4232      1.835300e-03  1.921031e-03  2.010712e-03  2.104521e-03
## ASV6479      3.285950e-04  3.494175e-04  3.716969e-04  3.955411e-04
## ASV0142     -2.528450e-03 -2.636546e-03 -2.748740e-03 -2.865143e-03
## ASV0378     -7.866226e-05 -7.862178e-05 -7.825018e-05 -7.750466e-05
## ASV1122      4.030033e-03  4.212794e-03  4.403443e-03  4.602286e-03
## ASV0123     -2.235583e-03 -2.330953e-03 -2.429920e-03 -2.532580e-03
## ASV2064      1.257946e-03  1.309366e-03  1.362585e-03  1.417645e-03
## ASV4459     -5.881164e-04 -6.153386e-04 -6.437615e-04 -6.734326e-04
## ASV0448      8.928385e-04  9.356824e-04  9.805708e-04  1.027598e-03
## ASV0397      1.866430e-03  1.950363e-03  2.037843e-03  2.129002e-03
## ASV0485      2.422892e-03  2.529279e-03  2.639949e-03  2.755040e-03
## ASV1566      3.868871e-03  4.041307e-03  4.220910e-03  4.407933e-03
## ASV1365      2.459804e-03  2.567691e-03  2.679907e-03  2.796591e-03
## ASV1065      4.660351e-03  4.869651e-03  5.087787e-03  5.315086e-03
## ASV0722     -2.716588e-04 -2.842872e-04 -2.975085e-04 -3.113519e-04
## ASV12660    -2.513293e-03 -2.621176e-03 -2.733156e-03 -2.849343e-03
## ASV0223      3.906977e-04  4.081211e-04  4.262649e-04  4.451539e-04
## ASV0229      9.816727e-04  1.026878e-03  1.074087e-03  1.123380e-03
## ASV0877      7.104009e-05  7.218671e-05  7.324160e-05  7.419299e-05
## ASV0983      2.442968e-03  2.548801e-03  2.658745e-03  2.772920e-03
## ASV0626     -1.422273e-04 -1.438064e-04 -1.450313e-04 -1.458539e-04
## ASV4146     -1.465166e-04 -1.541225e-04 -1.621403e-04 -1.705944e-04
## ASV4175     -2.991304e-03 -3.126289e-03 -3.267004e-03 -3.413659e-03
## ASV2082     -1.461730e-03 -1.534513e-03 -1.611056e-03 -1.691564e-03
## ASV2272      1.347792e-03  1.407455e-03  1.469579e-03  1.534252e-03
## ASV2245     -2.181149e-03 -2.279803e-03 -2.382661e-03 -2.489879e-03
## ASV0590     -1.885554e-03 -1.979581e-03 -2.078450e-03 -2.182419e-03
## ASV0217     -1.670355e-04 -1.678661e-04 -1.681542e-04 -1.678316e-04
## ASV0416      1.629352e-03  1.695334e-03  1.763460e-03  1.833752e-03
## ASV1056      1.957735e-03  2.048761e-03  2.143912e-03  2.243362e-03
## ASV7777     -2.932255e-03 -3.066900e-03 -3.207496e-03 -3.354288e-03
## ASV0455      3.669965e-04  3.832237e-04  4.001004e-04  4.176457e-04
## ASV0604      1.205464e-03  1.263189e-03  1.323666e-03  1.387024e-03
## ASV6100     -2.081608e-03 -2.177367e-03 -2.277370e-03 -2.381791e-03
## ASV11359    -4.589924e-03 -4.793633e-03 -5.005666e-03 -5.226299e-03
## ASV6604      8.415185e-04  8.808949e-04  9.220842e-04  9.651671e-04
## ASV5004     -1.320576e-03 -1.380667e-03 -1.443359e-03 -1.508751e-03
## ASV1483     -8.372247e-04 -8.759482e-04 -9.163960e-04 -9.586386e-04
## ASV9773     -2.069104e-03 -2.163369e-03 -2.261728e-03 -2.364341e-03
## ASV4059      1.574206e-03  1.651137e-03  1.731896e-03  1.816676e-03
## ASV1193      2.494981e-03  2.606215e-03  2.722081e-03  2.842746e-03
## ASV4610     -2.999816e-04 -3.084726e-04 -3.168871e-04 -3.251868e-04
## ASV0742     -5.175228e-04 -5.357172e-04 -5.542424e-04 -5.730748e-04
## ASV1502      3.451236e-05  3.282078e-05  3.078414e-05  2.836748e-05
## ASV0195     -1.037393e-04 -1.100633e-04 -1.168023e-04 -1.239841e-04
## ASV1213      2.093788e-03  2.182244e-03  2.273935e-03  2.368938e-03
## ASV1648     -1.947730e-03 -2.037131e-03 -2.130480e-03 -2.227936e-03
## ASV6984     -1.812696e-03 -1.895751e-03 -1.982455e-03 -2.072957e-03
## ASV0396     -1.541443e-04 -1.559884e-04 -1.574959e-04 -1.586227e-04
## ASV4297      2.944111e-03  3.069400e-03  3.199401e-03  3.334242e-03
## ASV2622      3.894322e-03  4.062587e-03  4.237389e-03  4.418919e-03
## ASV3512      1.397460e-03  1.464514e-03  1.534801e-03  1.608477e-03
## ASV2411      2.442876e-03  2.555557e-03  2.673242e-03  2.796137e-03
## ASV2291     -1.341832e-03 -1.410396e-03 -1.482632e-03 -1.558746e-03
## ASV0807      2.827622e-03  2.958827e-03  3.095906e-03  3.239099e-03
## ASV1292      9.079728e-04  9.464141e-04  9.862684e-04  1.027570e-03
## ASV1035      2.610766e-03  2.722113e-03  2.837640e-03  2.957458e-03
## ASV0070     -7.700249e-05 -7.844058e-05 -7.976077e-05 -8.094319e-05
## ASV0255      2.389848e-04  2.480725e-04  2.573801e-04  2.668993e-04
## ASV0057     -9.564668e-04 -9.961657e-04 -1.037257e-03 -1.079768e-03
## ASV0077     -1.547886e-04 -1.601398e-04 -1.655788e-04 -1.710973e-04
## ASV0625      1.883457e-03  1.963244e-03  2.045972e-03  2.131708e-03
## ASV2464      1.259839e-02  1.313319e-02  1.368782e-02  1.426278e-02
## ASV1315      3.826021e-03  3.999645e-03  4.180834e-03  4.369894e-03
## ASV2673      3.320646e-03  3.476488e-03  3.639530e-03  3.810094e-03
## ASV2161      1.423701e-03  1.490197e-03  1.559748e-03  1.632490e-03
## ASV0337     -7.553937e-04 -7.897077e-04 -8.255115e-04 -8.628641e-04
## ASV7680     -4.725812e-03 -4.942570e-03 -5.168873e-03 -5.405108e-03
## ASV0611      2.476937e-03  2.590742e-03  2.709591e-03  2.833691e-03
## ASV3118     -2.962382e-03 -3.101023e-03 -3.246003e-03 -3.397594e-03
## ASV1284      1.879416e-03  1.963859e-03  2.051670e-03  2.142935e-03
## ASV0889      1.759093e-03  1.835542e-03  1.915018e-03  1.997620e-03
## ASV4649     -9.973277e-04 -1.042414e-03 -1.089426e-03 -1.138438e-03
## ASV1108     -2.303198e-03 -2.412845e-03 -2.527677e-03 -2.647931e-03
## ASV0738      5.851057e-04  6.203284e-04  6.578334e-04  6.977742e-04
## ASV0473     -2.298374e-04 -2.423910e-04 -2.556773e-04 -2.697408e-04
## ASV0598     -1.302601e-03 -1.357931e-03 -1.415339e-03 -1.474882e-03
## ASV0429      1.880453e-03  1.962230e-03  2.047209e-03  2.135484e-03
## ASV1549      2.527697e-03  2.646974e-03  2.771811e-03  2.902461e-03
## ASV1203      2.060425e-03  2.150184e-03  2.243483e-03  2.340430e-03
## ASV4532      1.407503e-05  1.300998e-05  1.176378e-05  1.031968e-05
## ASV0274     -2.942052e-04 -3.042928e-04 -3.145611e-04 -3.249992e-04
## ASV0163     -1.707797e-03 -1.780004e-03 -1.854876e-03 -1.932483e-03
## ASV1298      6.953639e-04  7.242036e-04  7.540710e-04  7.849909e-04
## ASV9424     -4.085650e-03 -4.274264e-03 -4.471311e-03 -4.677144e-03
## ASV0412      3.448671e-03  3.599436e-03  3.756199e-03  3.919148e-03
## ASV0284      8.322640e-04  8.653731e-04  8.995007e-04  9.346515e-04
## ASV0620     -9.778226e-04 -1.027007e-03 -1.078731e-03 -1.133129e-03
## ASV0153     -2.848953e-03 -2.982655e-03 -3.122529e-03 -3.268849e-03
## ASV0498      1.099121e-03  1.151309e-03  1.205909e-03  1.263022e-03
## ASV0097      7.357226e-04  7.701315e-04  8.061245e-04  8.437726e-04
## ASV0104     -4.795296e-03 -5.008557e-03 -5.230670e-03 -5.461952e-03
## ASV1282      1.268822e-03  1.325545e-03  1.384574e-03  1.445977e-03
## ASV3883     -1.466408e-03 -1.536257e-03 -1.609391e-03 -1.685958e-03
## ASV0801      9.382681e-04  9.830744e-04  1.029999e-03  1.079139e-03
## ASV1611     -3.338205e-03 -3.492518e-03 -3.653741e-03 -3.822164e-03
## ASV0227     -7.285150e-04 -7.644932e-04 -8.022785e-04 -8.419619e-04
## ASV0833      9.590779e-04  1.003106e-03  1.049075e-03  1.097062e-03
## ASV0718      4.669628e-03  4.881248e-03  5.101980e-03  5.332176e-03
## ASV1139      5.967572e-04  6.183404e-04  6.403621e-04  6.627965e-04
## ASV0766     -8.216244e-04 -8.608898e-04 -9.020251e-04 -9.451181e-04
## ASV2091      4.730410e-03  4.930004e-03  5.136954e-03  5.351446e-03
## ASV1238     -1.633694e-03 -1.698350e-03 -1.765198e-03 -1.834298e-03
## ASV9193     -7.238602e-04 -7.677141e-04 -8.142424e-04 -8.635937e-04
## ASV0290      7.295571e-05  7.413565e-05  7.519347e-05  7.611172e-05
## ASV0231      1.510411e-03  1.576632e-03  1.645502e-03  1.717106e-03
## ASV0185      6.225429e-04  6.562405e-04  6.918630e-04  7.295237e-04
## ASV2330      1.374139e-03  1.430943e-03  1.489708e-03  1.550466e-03
## ASV3119     -8.292828e-04 -8.716489e-04 -9.162609e-04 -9.632415e-04
## ASV2368     -2.098429e-03 -2.197666e-03 -2.301555e-03 -2.410312e-03
## ASV0122     -6.690248e-04 -6.977091e-04 -7.274944e-04 -7.584130e-04
## ASV1044      2.257671e-03  2.364943e-03  2.477280e-03  2.594917e-03
## ASV0160     -1.108148e-03 -1.153687e-03 -1.200797e-03 -1.249505e-03
## ASV0326      3.265679e-04  3.411921e-04  3.564289e-04  3.723002e-04
## ASV1388      5.694433e-03  5.946669e-03  6.209252e-03  6.482538e-03
## ASV0792      3.427804e-03  3.576388e-03  3.730763e-03  3.891100e-03
## ASV0036     -9.209351e-04 -9.639007e-04 -1.008825e-03 -1.055794e-03
## ASV2125      3.149065e-03  3.287863e-03  3.432288e-03  3.582524e-03
## ASV1075      1.542118e-04  1.616345e-04  1.694198e-04  1.775858e-04
## ASV0390      1.748655e-03  1.832854e-03  1.921130e-03  2.013681e-03
## ASV3790     -2.605678e-03 -2.723763e-03 -2.846949e-03 -2.975438e-03
## ASV1535     -5.162169e-04 -5.445278e-04 -5.744600e-04 -6.061073e-04
## ASV0263      2.351843e-03  2.456712e-03  2.565926e-03  2.679637e-03
## ASV0675      4.586453e-03  4.799157e-03  5.021426e-03  5.253661e-03
## ASV3348      4.956989e-04  5.200319e-04  5.455847e-04  5.724197e-04
## ASV0058     -1.501330e-03 -1.566301e-03 -1.633814e-03 -1.703948e-03
## ASV4142      1.804090e-03  1.882431e-03  1.963848e-03  2.048433e-03
## ASV0059     -1.238312e-03 -1.291396e-03 -1.346512e-03 -1.403718e-03
## ASV0013     -1.730757e-03 -1.808216e-03 -1.888934e-03 -1.973030e-03
## ASV0033     -8.775694e-04 -9.186138e-04 -9.615390e-04 -1.006427e-03
## ASV4354     -1.162715e-03 -1.215406e-03 -1.270376e-03 -1.327717e-03
## ASV0022     -6.942695e-04 -7.268593e-04 -7.609536e-04 -7.966192e-04
## ASV0134     -7.584121e-04 -7.948052e-04 -8.329512e-04 -8.729342e-04
## ASV0415      1.000619e-04  1.080100e-04  1.165697e-04  1.257839e-04
## ASV10103    -4.139712e-03 -4.330655e-03 -4.530105e-03 -4.738411e-03
## ASV1613      3.109789e-03  3.243796e-03  3.382953e-03  3.527404e-03
## ASV0135     -4.956636e-04 -5.155197e-04 -5.359928e-04 -5.570853e-04
## ASV0469     -3.940668e-03 -4.111876e-03 -4.289832e-03 -4.474746e-03
## ASV0471      2.937008e-03  3.071387e-03  3.211612e-03  3.357905e-03
## ASV0451     -4.623515e-04 -4.871133e-04 -5.132875e-04 -5.409595e-04
## ASV0747      1.039727e-03  1.088538e-03  1.139581e-03  1.192953e-03
## ASV1314     -1.308989e-03 -1.371614e-03 -1.437238e-03 -1.506003e-03
## ASV0425     -5.591610e-03 -5.827272e-03 -6.071616e-03 -6.324862e-03
## ASV0559     -1.601356e-03 -1.671094e-03 -1.743627e-03 -1.819052e-03
## ASV0148     -8.760839e-04 -9.112841e-04 -9.476142e-04 -9.850860e-04
## ASV0129     -2.313658e-04 -2.357517e-04 -2.398151e-04 -2.435025e-04
## ASV1072      6.132701e-04  6.375886e-04  6.626754e-04  6.885392e-04
## ASV2390      2.110606e-03  2.198066e-03  2.288555e-03  2.382124e-03
## ASV0548      1.907884e-03  1.993400e-03  2.082529e-03  2.175406e-03
## ASV0168     -1.269179e-03 -1.324209e-03 -1.381403e-03 -1.440828e-03
## ASV0066     -1.052700e-03 -1.099575e-03 -1.148393e-03 -1.199222e-03
## ASV0468     -6.845923e-04 -7.155932e-04 -7.479286e-04 -7.816502e-04
## ASV0172     -3.001371e-04 -3.109200e-04 -3.219313e-04 -3.331610e-04
## ASV0236     -5.304085e-04 -5.458470e-04 -5.612409e-04 -5.765334e-04
## ASV0250      7.694609e-04  8.124338e-04  8.579395e-04  9.061307e-04
## ASV0338      7.002525e-04  7.356941e-04  7.729531e-04  8.121199e-04
## ASV0450     -6.650338e-05 -7.064212e-05 -7.506159e-05 -7.978173e-05
## ASV0377      1.456599e-03  1.521507e-03  1.589109e-03  1.659500e-03
## ASV1022      1.906571e-04  1.994217e-04  2.085779e-04  2.181427e-04
## ASV6174     -1.804572e-04 -1.895625e-04 -1.991455e-04 -2.092330e-04
## ASV0786      1.127826e-04  1.154460e-04  1.180026e-04  1.204289e-04
## ASV0053     -1.355202e-03 -1.416816e-03 -1.481097e-03 -1.548149e-03
## ASV0697     -1.062464e-03 -1.108242e-03 -1.155804e-03 -1.205207e-03
## ASV0785      1.989260e-03  2.076755e-03  2.167819e-03  2.262577e-03
## ASV1967     -1.818247e-03 -1.897110e-03 -1.979062e-03 -2.064198e-03
## ASV0385      2.784526e-04  2.936652e-04  3.097188e-04  3.266566e-04
## ASV0295      9.344281e-05  9.993115e-05  1.069007e-04  1.143876e-04
## ASV0072     -1.271849e-03 -1.325972e-03 -1.382130e-03 -1.440375e-03
## ASV0157     -4.491938e-04 -4.660555e-04 -4.833223e-04 -5.009807e-04
## ASV0501      3.385317e-03  3.543686e-03  3.709167e-03  3.882040e-03
## ASV10729    -3.963837e-03 -4.146047e-03 -4.336328e-03 -4.535010e-03
## ASV1470      2.160411e-03  2.241664e-03  2.325081e-03  2.410643e-03
## ASV0050     -3.020011e-03 -3.153145e-03 -3.291704e-03 -3.435873e-03
## ASV0411     -5.503133e-04 -5.749412e-04 -6.006255e-04 -6.274092e-04
## ASV0549      9.860982e-04  1.031896e-03  1.079780e-03  1.129842e-03
## ASV0184      3.009026e-04  3.142185e-04  3.280816e-04  3.425114e-04
## ASV0705      7.883564e-04  8.241051e-04  8.613851e-04  9.002536e-04
## ASV1715      1.774594e-03  1.854498e-03  1.937798e-03  2.024621e-03
## ASV0603      2.861633e-04  2.997703e-04  3.140265e-04  3.289633e-04
## ASV0826      2.381118e-03  2.484927e-03  2.592861e-03  2.705050e-03
## ASV0034     -9.569243e-04 -9.981964e-04 -1.041059e-03 -1.085557e-03
## ASV0838      1.312369e-03  1.367440e-03  1.424460e-03  1.483463e-03
## ASV0614     -1.109254e-03 -1.158785e-03 -1.210384e-03 -1.264127e-03
## ASV0014     -1.736216e-03 -1.813427e-03 -1.893845e-03 -1.977582e-03
## ASV0585     -1.547175e-04 -1.624735e-04 -1.706475e-04 -1.792645e-04
## ASV0016     -1.821508e-03 -1.902555e-03 -1.986971e-03 -2.074875e-03
## ASV5394     -1.785359e-03 -1.866296e-03 -1.950714e-03 -2.038745e-03
## ASV0666      3.273778e-03  3.414365e-03  3.560320e-03  3.711794e-03
## ASV2085      6.605265e-04  6.796568e-04  6.986741e-04  7.174962e-04
## ASV0003     -1.263051e-03 -1.319143e-03 -1.377559e-03 -1.438380e-03
## ASV0346      3.415740e-04  3.599150e-04  3.792867e-04  3.997479e-04
## ASV0267     -1.436374e-04 -1.473146e-04 -1.508807e-04 -1.543061e-04
## ASV0353      1.070402e-03  1.122741e-03  1.177640e-03  1.235219e-03
## ASV2419      3.431864e-03  3.581695e-03  3.737483e-03  3.899415e-03
## ASV0447      1.474348e-03  1.543705e-03  1.616258e-03  1.692145e-03
## ASV0654      2.381209e-03  2.488650e-03  2.600670e-03  2.717439e-03
## ASV0151      2.153665e-04  2.272048e-04  2.397416e-04  2.530208e-04
## ASV0065     -9.474963e-04 -9.881818e-04 -1.030431e-03 -1.074289e-03
## ASV0527      2.561307e-03  2.675563e-03  2.794582e-03  2.918536e-03
## ASV4055     -6.199576e-04 -6.506218e-04 -6.828463e-04 -7.167140e-04
## ASV0166     -1.251218e-03 -1.301088e-03 -1.352561e-03 -1.405658e-03
## ASV0417     -9.531022e-04 -9.928931e-04 -1.034095e-03 -1.076736e-03
## ASV0078     -6.773600e-04 -7.056261e-04 -7.349042e-04 -7.652168e-04
## ASV0322     -7.669509e-04 -7.945254e-04 -8.227353e-04 -8.515670e-04
## ASV0156     -1.587447e-03 -1.656221e-03 -1.727730e-03 -1.802067e-03
## ASV0648     -4.992441e-03 -5.222394e-03 -5.462581e-03 -5.713424e-03
## ASV0407     -1.481696e-04 -1.554097e-04 -1.629941e-04 -1.709373e-04
## ASV2030     -6.600933e-04 -6.891539e-04 -7.194199e-04 -7.509382e-04
## ASV0300      4.397378e-04  4.615013e-04  4.843475e-04  5.083288e-04
## ASV1150     -3.252102e-05 -3.335602e-05 -3.417119e-05 -3.496118e-05
## ASV0958      1.278734e-03  1.339704e-03  1.403575e-03  1.470482e-03
## ASV0216     -1.410567e-03 -1.472029e-03 -1.535939e-03 -1.602378e-03
## ASV0446      2.155659e-03  2.256419e-03  2.361767e-03  2.471900e-03
## ASV0367     -1.601326e-03 -1.674366e-03 -1.750600e-03 -1.830155e-03
## ASV0200     -8.876502e-04 -9.270466e-04 -9.680778e-04 -1.010803e-03
## ASV0334     -5.087716e-04 -5.274803e-04 -5.466261e-04 -5.661964e-04
## ASV1311      5.776801e-04  6.021263e-04  6.274726e-04  6.537406e-04
## ASV0458      1.237025e-03  1.288351e-03  1.341463e-03  1.396392e-03
## ASV1371      1.383406e-04  1.449342e-04  1.518345e-04  1.590542e-04
## ASV0418      2.991533e-03  3.114874e-03  3.242513e-03  3.374537e-03
## ASV0004      2.936395e-04  3.061044e-04  3.190334e-04  3.324383e-04
## ASV1943      1.032235e-02  1.075548e-02  1.120441e-02  1.166954e-02
## ASV1495     -5.193668e-04 -5.490374e-04 -5.805234e-04 -6.139406e-04
## ASV0901     -1.999382e-03 -2.091918e-03 -2.188621e-03 -2.289668e-03
## ASV0628      8.915038e-04  9.286515e-04  9.671019e-04  1.006878e-03
## ASV0400      4.782759e-04  4.994654e-04  5.215140e-04  5.444490e-04
## ASV0116     -5.598062e-04 -5.854346e-04 -6.121943e-04 -6.401321e-04
## ASV0788      3.975084e-03  4.156964e-03  4.346830e-03  4.545003e-03
## ASV0117      3.568769e-04  3.741177e-04  3.921970e-04  4.111555e-04
## ASV3137     -8.857285e-06 -8.918783e-06 -8.948876e-06 -8.942973e-06
## ASV0001      3.518880e-04  3.666154e-04  3.818763e-04  3.976832e-04
## ASV1651      8.999133e-04  9.370351e-04  9.754492e-04  1.015181e-03
## ASV1692      3.329386e-03  3.482988e-03  3.643443e-03  3.811035e-03
## ASV0660      1.042226e-03  1.083579e-03  1.126165e-03  1.169981e-03
## ASV0508     -2.766564e-05 -2.977810e-05 -3.205327e-05 -3.450307e-05
## ASV1660     -9.812962e-04 -1.028636e-03 -1.078256e-03 -1.130264e-03
## ASV0233      6.998420e-04  7.311556e-04  7.637892e-04  7.977921e-04
## ASV1343     -2.246255e-03 -2.349883e-03 -2.458147e-03 -2.571240e-03
## ASV0209      9.987715e-04  1.041119e-03  1.085036e-03  1.130563e-03
## ASV0193     -1.304399e-03 -1.355257e-03 -1.407658e-03 -1.461615e-03
## ASV0357      2.725163e-04  2.864373e-04  3.011000e-04  3.165458e-04
## ASV0198      8.253964e-04  8.630441e-04  9.023201e-04  9.432863e-04
## ASV0007      3.671694e-04  3.824036e-04  3.981784e-04  4.145055e-04
## ASV1772     -5.376593e-04 -5.600962e-04 -5.833095e-04 -6.073097e-04
## ASV0009      3.421538e-04  3.562345e-04  3.708047e-04  3.858741e-04
## ASV0006     -5.042282e-05 -5.348297e-05 -5.673682e-05 -6.019638e-05
## ASV0011     -7.056071e-04 -7.379242e-04 -7.716606e-04 -8.068730e-04
## ASV0015      2.232208e-04  2.324223e-04  2.419397e-04  2.517782e-04
## ASV0017      2.424493e-04  2.524472e-04  2.627897e-04  2.734832e-04
## ASV0235     -8.899906e-04 -9.320240e-04 -9.760020e-04 -1.022010e-03
## ASV0382      3.814303e-04  4.005911e-04  4.207128e-04  4.418402e-04
## ASV2357      2.829191e-03  2.958737e-03  3.093988e-03  3.235177e-03
## ASV0567     -7.399750e-04 -7.728949e-04 -8.071952e-04 -8.429281e-04
## ASV0165      4.986036e-04  5.217203e-04  5.458754e-04  5.711123e-04
## ASV0005      5.913854e-04  6.172235e-04  6.440932e-04  6.720276e-04
## ASV0384     -1.902100e-05 -1.791144e-05 -1.657380e-05 -1.498298e-05
## ASV0002      1.018509e-04  1.063580e-04  1.110502e-04  1.159340e-04
## ASV3017      3.789438e-03  3.952972e-03  4.122858e-03  4.299285e-03
## ASV0091     -1.070512e-07 -6.029130e-09  1.061180e-07  2.300191e-07
## ASV0186     -1.566740e-03 -1.637284e-03 -1.710817e-03 -1.787448e-03
## ASV0370      4.686204e-04  4.905723e-04  5.135368e-04  5.375594e-04
## ASV0018      8.083169e-04  8.437759e-04  8.806641e-04  9.190289e-04
## ASV1377      1.222946e-02  1.276176e-02  1.331505e-02  1.388997e-02
## ASV0019      8.469821e-04  8.841794e-04  9.228799e-04  9.631336e-04
## ASV0023     -2.626327e-04 -2.753553e-04 -2.886901e-04 -3.026655e-04
## ASV2194      9.544469e-04  9.968054e-04  1.040945e-03  1.086936e-03
## ASV1155      1.854179e-03  1.938094e-03  2.025595e-03  2.116816e-03
## ASV0510     -1.307131e-03 -1.355599e-03 -1.405333e-03 -1.456330e-03
## ASV2371     -2.024942e-03 -2.109789e-03 -2.197691e-03 -2.288716e-03
## ASV0024     -3.523133e-04 -3.691029e-04 -3.866801e-04 -4.050796e-04
## ASV2452      2.333599e-03  2.431137e-03  2.532185e-03  2.636823e-03
## ASV2332     -2.747398e-03 -2.867113e-03 -2.991404e-03 -3.120382e-03
## ASV2591      1.966497e-03  2.065892e-03  2.170434e-03  2.280389e-03
## ASV0521      1.328787e-03  1.390242e-03  1.454442e-03  1.521503e-03
## ASV5542      1.161879e-03  1.215598e-03  1.271702e-03  1.330287e-03
## ASV0336     -4.007402e-04 -4.166912e-04 -4.331890e-04 -4.502493e-04
## ASV10102     2.444753e-03  2.558435e-03  2.677263e-03  2.801456e-03
## ASV16823    -3.373261e-03 -3.514061e-03 -3.659896e-03 -3.810876e-03
## ASV3104      1.861234e-02  1.938908e-02  2.019358e-02  2.102645e-02
## ASV0781      2.215907e-03  2.316701e-03  2.421871e-03  2.531588e-03
## ASV10899     1.456642e-03  1.530519e-03  1.608257e-03  1.690060e-03
## ASV11222    -5.890490e-03 -6.136297e-03 -6.390888e-03 -6.654457e-03
## ASV11327    -5.297211e-03 -5.518219e-03 -5.747122e-03 -5.984094e-03
## ASV12458    -5.888342e-03 -6.133968e-03 -6.388364e-03 -6.651724e-03
## ASV1636      4.995985e-04  5.235615e-04  5.486633e-04  5.749552e-04
## ASV1890     -3.792420e-03 -3.948188e-03 -4.109298e-03 -4.275846e-03
## ASV2898      4.590320e-03  4.790582e-03  4.998781e-03  5.215165e-03
## ASV8328      3.081059e-04  3.364955e-04  3.673598e-04  4.008983e-04
## ASV0709     -5.115132e-03 -5.340716e-03 -5.575464e-03 -5.819681e-03
## ASV0856      3.663070e-03  3.835503e-03  4.015918e-03  4.204666e-03
## ASV0909     -1.568415e-04 -1.502670e-04 -1.422433e-04 -1.326207e-04
## ASV0937     -3.007812e-03 -3.144263e-03 -3.286622e-03 -3.435124e-03
## ASV11390    -8.339170e-03 -8.686958e-03 -9.047160e-03 -9.420049e-03
## ASV11966     2.110795e-03  2.212901e-03  2.319951e-03  2.432182e-03
## ASV12990     1.372031e-03  1.433993e-03  1.498589e-03  1.565916e-03
## ASV14797     2.294336e-03  2.393461e-03  2.496431e-03  2.603357e-03
## ASV14904    -1.183731e-02 -1.233098e-02 -1.284227e-02 -1.337158e-02
## ASV15304     1.152554e-03  1.211843e-03  1.274285e-03  1.340049e-03
## ASV16696    -4.186740e-03 -4.361326e-03 -4.542143e-03 -4.729327e-03
## ASV1690      7.423936e-03  7.771722e-03  8.135358e-03  8.515510e-03
## ASV2029      5.196326e-03  5.424188e-03  5.661190e-03  5.907626e-03
## ASV2834      8.473640e-03  8.857158e-03  9.257116e-03  9.674139e-03
## ASV4003      5.233618e-03  5.486887e-03  5.752498e-03  6.031049e-03
## ASV4064      3.169175e-03  3.310681e-03  3.458089e-03  3.611609e-03
## ASV4294      1.892800e-03  1.989460e-03  2.091256e-03  2.198470e-03
## ASV4609      9.522569e-04  9.925448e-04  1.034366e-03  1.077769e-03
## ASV6283     -3.917340e-03 -4.080723e-03 -4.249941e-03 -4.425122e-03
## ASV6491     -5.585308e-03 -5.818215e-03 -6.059436e-03 -6.309154e-03
## ASV7453      2.681873e-03  2.812109e-03  2.948668e-03  3.091848e-03
## ASV7959      7.506256e-04  7.932003e-04  8.383380e-04  8.861964e-04
## ASV8219      5.756431e-02  5.996460e-02  6.245056e-02  6.502409e-02
## ASV8547     -5.007964e-03 -5.216745e-03 -5.432975e-03 -5.656818e-03
## ASV9319      2.266029e-03  2.371835e-03  2.482466e-03  2.598132e-03
## ASV9382     -9.658935e-03 -1.006158e-02 -1.047859e-02 -1.091028e-02
## ASV11516    -6.512911e-03 -6.784359e-03 -7.065487e-03 -7.356508e-03
## ASV14377    -4.727504e-03 -4.924502e-03 -5.128523e-03 -5.339720e-03
## ASV1867      4.131168e-03  4.320788e-03  4.518793e-03  4.725527e-03
## ASV1895      6.929264e-04  7.231132e-04  7.544380e-04  7.869238e-04
## ASV3168      2.213037e-03  2.308082e-03  2.406745e-03  2.509126e-03
## ASV4449      1.438184e-02  1.502033e-02  1.568522e-02  1.637746e-02
## ASV6596      2.865859e-03  3.007196e-03  3.155655e-03  3.311599e-03
## ASV7492     -5.636684e-04 -5.787755e-04 -5.936500e-04 -6.082129e-04
## ASV9854     -1.215357e-03 -1.264259e-03 -1.314750e-03 -1.366851e-03
## ASV6296      1.060800e-01  1.104994e-01  1.150764e-01  1.198142e-01
## ASV4201      1.295822e-03  1.366977e-03  1.442278e-03  1.521975e-03
## ASV0552      2.687609e-03  2.811096e-03  2.940036e-03  3.074647e-03
## ASV3671     -1.326941e-03 -1.382550e-03 -1.440208e-03 -1.499972e-03
## ASV3529     -6.075677e-04 -6.266437e-04 -6.458437e-04 -6.651200e-04
## ASV1060      1.037571e-03  1.085513e-03  1.135604e-03  1.187937e-03
## ASV0239     -1.037123e-03 -1.078831e-03 -1.121863e-03 -1.166228e-03
## ASV5711     -4.172632e-03 -4.353668e-03 -4.541825e-03 -4.737328e-03
## ASV4152     -6.839589e-03 -7.141832e-03 -7.456420e-03 -7.783773e-03
## ASV1461      3.092938e-03  3.222749e-03  3.357242e-03  3.496524e-03
## ASV2877      1.597840e-03  1.664652e-03  1.733845e-03  1.805468e-03
## ASV0012      2.273124e-04  2.375845e-04  2.482960e-04  2.594635e-04
## ASV9823      4.464599e-04  4.588010e-04  4.711097e-04  4.833513e-04
## ASV0008      2.420999e-04  2.529352e-04  2.642255e-04  2.759874e-04
## ASV7832     -4.301130e-03 -4.493874e-03 -4.694744e-03 -4.904041e-03
## ASV1915     -6.880863e-05 -6.942239e-05 -6.987176e-05 -7.013849e-05
## ASV0055      1.250293e-05  1.165683e-05  1.064495e-05  9.449231e-06
## ASV0032      4.492062e-04  4.685297e-04  4.885974e-04  5.094309e-04
## ASV2977     -5.948630e-03 -6.208000e-03 -6.477633e-03 -6.757849e-03
## ASV0466      4.343538e-03  4.522752e-03  4.708149e-03  4.899837e-03
## ASV3866      3.090154e-03  3.232000e-03  3.380114e-03  3.534755e-03
## ASV0040      8.151619e-04  8.521278e-04  8.906865e-04  9.308991e-04
## ASV0496     -3.481041e-04 -3.695235e-04 -3.923608e-04 -4.167126e-04
## ASV0052      1.033428e-03  1.079537e-03  1.127568e-03  1.177590e-03
## ASV3828     -6.336144e-03 -6.616525e-03 -6.908454e-03 -7.212341e-03
## ASV1930      2.000215e-03  2.089461e-03  2.182406e-03  2.279177e-03
## ASV2126      2.450961e-03  2.558801e-03  2.671005e-03  2.787721e-03
## ASV0793      2.826558e-03  2.955313e-03  3.089650e-03  3.229784e-03
## ASV0299     -2.238266e-04 -2.338637e-04 -2.443315e-04 -2.552479e-04
## ASV0208      2.036464e-03  2.130775e-03  2.229309e-03  2.332241e-03
## ASV0511     -1.119558e-03 -1.166331e-03 -1.214787e-03 -1.264967e-03
## ASV1123     -3.533769e-03 -3.678679e-03 -3.828541e-03 -3.983442e-03
## ASV0099     -9.924117e-05 -1.021388e-04 -1.050240e-04 -1.078850e-04
## ASV0752     -1.163659e-03 -1.220319e-03 -1.279772e-03 -1.342155e-03
## ASV0883      1.447325e-03  1.514710e-03  1.585142e-03  1.658750e-03
## ASV0683      3.021929e-03  3.162992e-03  3.310483e-03  3.464678e-03
## ASV4117     -7.245457e-03 -7.564905e-03 -7.897360e-03 -8.243267e-03
## ASV2172      5.743042e-04  5.984238e-04  6.234224e-04  6.493212e-04
## ASV0330     -8.462464e-04 -8.841640e-04 -9.236908e-04 -9.648883e-04
## ASV0728      4.467285e-03  4.667661e-03  4.876470e-03  5.094017e-03
## ASV0499      1.103173e-03  1.154759e-03  1.208710e-03  1.265131e-03
## ASV0120     -1.856468e-03 -1.939249e-03 -2.025467e-03 -2.115241e-03
## ASV1446      1.726747e-03  1.793583e-03  1.862285e-03  1.932835e-03
## ASV17171    -3.315933e-03 -3.464278e-03 -3.618867e-03 -3.779934e-03
## ASV0533      3.191502e-04  3.346565e-04  3.509220e-04  3.679839e-04
## ASV2495     -1.251177e-03 -1.313073e-03 -1.378118e-03 -1.446478e-03
## ASV5582      1.372711e-03  1.423575e-03  1.475666e-03  1.528953e-03
## ASV1488      1.342058e-03  1.409743e-03  1.480791e-03  1.555355e-03
## ASV0682      8.294494e-04  8.689594e-04  9.103440e-04  9.536908e-04
## ASV0068     -8.833268e-04 -9.232845e-04 -9.649456e-04 -1.008373e-03
## ASV1987     -3.371774e-03 -3.532241e-03 -3.700297e-03 -3.876293e-03
## ASV0035     -1.585790e-04 -1.686573e-04 -1.794332e-04 -1.909572e-04
## ASV7192     -2.431698e-03 -2.535445e-03 -2.643094e-03 -2.754747e-03
## ASV0873      6.273627e-04  6.143419e-04  5.973311e-04  5.759161e-04
## ASV4749     -8.916906e-05 -1.030637e-04 -1.184318e-04 -1.354058e-04
## ASV2174      2.241741e-03  2.329228e-03  2.419441e-03  2.512421e-03
## ASV1476     -1.545010e-03 -1.615810e-03 -1.689748e-03 -1.766956e-03
## ASV0740     -5.352072e-03 -5.599280e-03 -5.857533e-03 -6.127290e-03
## ASV0170     -6.850440e-04 -7.160253e-04 -7.483337e-04 -7.820198e-04
## ASV2466     -5.120063e-03 -5.350222e-03 -5.590158e-03 -5.840240e-03
## ASV1709      2.087578e-03  2.176282e-03  2.268324e-03  2.363797e-03
## ASV6170     -1.186930e-02 -1.238544e-02 -1.292246e-02 -1.348111e-02
## ASV3673      3.521281e-03  3.671375e-03  3.827319e-03  3.989310e-03
## ASV1745      4.662769e-04  4.777247e-04  4.890055e-04  5.000768e-04
## ASV0380     -2.575665e-03 -2.659739e-03 -2.745040e-03 -2.831458e-03
## ASV0426      2.243692e-04  2.405327e-04  2.578572e-04  2.764214e-04
## ASV0202      5.858844e-05  6.545778e-05  7.298418e-05  8.122235e-05
## ASV6350     -3.812499e-03 -3.968586e-03 -4.130317e-03 -4.297861e-03
## ASV0713     -1.683824e-03 -1.760670e-03 -1.840883e-03 -1.924597e-03
## ASV1822      1.694575e-04  1.802550e-04  1.917334e-04  2.039318e-04
## ASV4569      4.977643e-03  5.190248e-03  5.411104e-03  5.640476e-03
## ASV0030     -4.620012e-04 -4.833863e-04 -5.057167e-04 -5.290292e-04
## ASV0331      1.844497e-03  1.931375e-03  2.022279e-03  2.117386e-03
## ASV2981      5.218739e-03  5.458721e-03  5.709248e-03  5.970732e-03
## ASV0828     -1.115377e-03 -1.196594e-03 -1.283769e-03 -1.377317e-03
## ASV2440      4.545202e-03  4.753889e-03  4.971765e-03  5.199199e-03
## ASV3006     -2.208204e-02 -2.288029e-02 -2.369922e-02 -2.453891e-02
## ASV3875      2.052911e-01  2.127111e-01  2.203233e-01  2.281284e-01
## ASV4511      2.576661e-03  2.696829e-03  2.822485e-03  2.953866e-03
## ASV4700     -8.118184e-03 -8.411562e-03 -8.712538e-03 -9.021135e-03
## ASV5804     -1.906257e-01 -1.975136e-01 -2.045798e-01 -2.118249e-01
## ASV6826      3.727165e-03  3.903286e-03  4.087635e-03  4.280584e-03
## ASV7280      3.505087e-03  3.673282e-03  3.849361e-03  4.033664e-03
## ASV7535     -8.116421e-03 -8.409690e-03 -8.710552e-03 -9.019031e-03
## ASV0651     -1.762841e-03 -1.836599e-03 -1.912968e-03 -1.991998e-03
## ASV0913      4.201594e-03  4.397540e-03  4.602455e-03  4.816736e-03
## ASV10832    -8.659771e-03 -8.972629e-03 -9.293584e-03 -9.622662e-03
## ASV1117     -9.179898e-03 -9.571135e-03 -9.977404e-03 -1.039917e-02
## ASV11329     1.588531e-03  1.673863e-03  1.763933e-03  1.859004e-03
## ASV13209     4.071093e-04  4.411415e-04  4.776416e-04  5.167507e-04
## ASV1345      2.279189e-03  2.387176e-03  2.499958e-03  2.617702e-03
## ASV1719     -1.219372e-02 -1.263421e-02 -1.308611e-02 -1.354944e-02
## ASV1886      2.480361e-03  2.588653e-03  2.701384e-03  2.818721e-03
## ASV2158      6.097167e-05  8.061512e-05  1.021324e-04  1.256345e-04
## ASV2189      4.226100e-03  4.414634e-03  4.611085e-03  4.815746e-03
## ASV2257      4.355624e-03  4.548262e-03  4.749023e-03  4.958232e-03
## ASV2283      9.443961e-03  9.784986e-03  1.013483e-02  1.049351e-02
## ASV2328      5.817618e-03  6.027664e-03  6.243138e-03  6.464057e-03
## ASV2434     -5.863804e-03 -6.108660e-03 -6.362764e-03 -6.626420e-03
## ASV2648      1.061681e-02  1.099997e-02  1.139302e-02  1.179599e-02
## ASV2698      1.165330e-02  1.218622e-02  1.274274e-02  1.332385e-02
## ASV2775      3.460775e-03  3.602842e-03  3.749890e-03  3.902032e-03
## ASV3171      5.116656e-03  5.301242e-03  5.490586e-03  5.684702e-03
## ASV3227      5.301987e-03  5.516491e-03  5.738239e-03  5.967370e-03
## ASV3397      2.702602e-03  2.828871e-03  2.960606e-03  3.097989e-03
## ASV3444      7.625218e-03  7.938556e-03  8.263343e-03  8.599931e-03
## ASV3556      2.127698e-02  2.204422e-02  2.283121e-02  2.363800e-02
## ASV3606     -5.000558e-02 -5.180850e-02 -5.365781e-02 -5.555364e-02
## ASV4190      7.428057e-03  7.762818e-03  8.111991e-03  8.476149e-03
## ASV4197      4.492938e-03  4.675196e-03  4.863733e-03  5.058688e-03
## ASV4722      7.015499e-03  7.321206e-03  7.639180e-03  7.969831e-03
## ASV4765      3.801461e-03  3.974885e-03  4.155513e-03  4.343569e-03
## ASV4809      1.256848e-02  1.302144e-02  1.348604e-02  1.396231e-02
## ASV4846      6.453832e-03  6.745536e-03  7.049625e-03  7.366550e-03
## ASV4903     -1.083135e-04 -9.478571e-05 -7.948346e-05 -6.228196e-05
## ASV4944     -5.147319e-03 -5.332814e-03 -5.523078e-03 -5.718121e-03
## ASV5151     -2.330830e-04 -3.396142e-04 -4.576133e-04 -5.879474e-04
## ASV5413     -1.132249e-02 -1.173051e-02 -1.214901e-02 -1.257803e-02
## ASV5537     -1.216290e-02 -1.260114e-02 -1.305064e-02 -1.351143e-02
## ASV5688      1.022239e-02  1.059065e-02  1.096838e-02  1.135559e-02
## ASV5752      3.387732e-03  3.546849e-03  3.712957e-03  3.886299e-03
## ASV6122     -1.309414e-02 -1.356583e-02 -1.404964e-02 -1.454559e-02
## ASV6135      6.873542e-03  7.121111e-03  7.375038e-03  7.635337e-03
## ASV6188     -4.173000e-02 -4.323280e-02 -4.477417e-02 -4.635422e-02
## ASV6216      1.000288e-02  1.041910e-02  1.085057e-02  1.129773e-02
## ASV6242      6.870410e-03  7.117747e-03  7.371426e-03  7.631463e-03
## ASV6383      4.295446e-02  4.450060e-02  4.608639e-02  4.771190e-02
## ASV6781      9.558753e-03  9.902771e-03  1.025560e-02  1.061727e-02
## ASV6799     -1.815057e-02 -1.880371e-02 -1.947358e-02 -2.016022e-02
## ASV7374     -3.851175e-03 -3.989738e-03 -4.131849e-03 -4.277516e-03
## ASV7539     -5.137603e-03 -5.322424e-03 -5.511975e-03 -5.706269e-03
## ASV8591     -1.307428e-02 -1.354455e-02 -1.402685e-02 -1.452121e-02
## ASV8637      5.739172e-02  5.945574e-02  6.157255e-02  6.374227e-02
## ASV12796    -7.573159e-03 -7.845479e-03 -8.124761e-03 -8.411021e-03
## ASV1934      4.315525e-03  4.511341e-03  4.715639e-03  4.928752e-03
## ASV22549     5.333697e-04  5.697609e-04  6.085282e-04  6.498038e-04
## ASV29857    -2.937335e-03 -3.042950e-03 -3.151266e-03 -3.262288e-03
## ASV3215      4.652730e-03  4.870988e-03  5.099363e-03  5.338316e-03
## ASV3236     -7.570960e-03 -7.843135e-03 -8.122265e-03 -8.408367e-03
## ASV3954     -7.569813e-03 -7.841907e-03 -8.120952e-03 -8.406963e-03
## ASV4850      5.073977e-03  5.256333e-03  5.443346e-03  5.635025e-03
## ASV5225      4.899277e-02  5.075329e-02  5.255875e-02  5.440925e-02
## ASV5532     -2.616614e-03 -2.710626e-03 -2.807037e-03 -2.905853e-03
## ASV7258      2.565747e-03  2.707987e-03  2.858387e-03  3.017412e-03
## ASV9474     -6.312844e-04 -6.376082e-04 -6.426883e-04 -6.463941e-04
## ASV11857    -9.831266e-03 -1.018451e-02 -1.054677e-02 -1.091807e-02
## ASV1202     -6.242757e-03 -6.467030e-03 -6.697027e-03 -6.932762e-03
## ASV14742     2.036481e-03  2.141955e-03  2.253020e-03  2.369971e-03
## ASV16652     1.512569e-03  1.584723e-03  1.660074e-03  1.738728e-03
## ASV2019      4.924589e-03  5.130851e-03  5.344776e-03  5.566580e-03
## ASV2410     -1.125851e-02 -1.176420e-02 -1.229171e-02 -1.284192e-02
## ASV2718      2.854458e-03  2.988474e-03  3.128585e-03  3.275044e-03
## ASV2738      8.045891e-03  8.378685e-03  8.723349e-03  9.080168e-03
## ASV2876      4.538334e-03  4.701324e-03  4.868471e-03  5.039785e-03
## ASV3177      6.080881e-03  6.299239e-03  6.523164e-03  6.752668e-03
## ASV4367      7.513355e-03  7.783112e-03  8.059745e-03  8.343267e-03
## ASV4635      2.778992e-03  2.921367e-03  3.070912e-03  3.227946e-03
## ASV4896      2.190607e-03  2.317590e-03  2.452189e-03  2.594852e-03
## ASV4907      2.328538e-03  2.446493e-03  2.570472e-03  2.700772e-03
## ASV5230     -5.849590e-03 -6.059689e-03 -6.275151e-03 -6.495991e-03
## ASV6509     -6.238791e-03 -6.462836e-03 -6.692599e-03 -6.928094e-03
## ASV7376     -4.463115e-03 -4.623370e-03 -4.787713e-03 -4.956154e-03
## ASV8163     -6.649808e-03 -6.888544e-03 -7.133368e-03 -7.384296e-03
## ASV8195     -5.846049e-03 -6.055899e-03 -6.271099e-03 -6.491661e-03
## ASV8923      2.120325e-03  2.225656e-03  2.336144e-03  2.452018e-03
## ASV9666     -2.844928e-03 -2.919779e-03 -2.994119e-03 -3.067717e-03
## ASV1482      3.467915e-03  3.630235e-03  3.799920e-03  3.977276e-03
## ASV2726      3.195977e-03  3.346132e-03  3.503112e-03  3.667198e-03
## ASV3281     -2.435778e-02 -2.523220e-02 -2.612892e-02 -2.704801e-02
## ASV4235     -2.435410e-02 -2.522825e-02 -2.612470e-02 -2.704350e-02
## ASV4808      5.317770e-03  5.540791e-03  5.772238e-03  6.012378e-03
## ASV4861     -1.296009e-02 -1.349884e-02 -1.405780e-02 -1.463762e-02
## ASV5276      7.575060e-03  7.890908e-03  8.218432e-03  8.557969e-03
## ASV5837      2.568089e-03  2.687223e-03  2.811795e-03  2.942050e-03
## ASV7098      3.672991e-03  3.841275e-03  4.017054e-03  4.200648e-03
## ASV8451     -4.143098e-03 -4.291662e-03 -4.444002e-03 -4.600127e-03
## ASV8694     -2.433139e-02 -2.520374e-02 -2.609826e-02 -2.701499e-02
## ASV0905     -1.199436e-03 -1.254991e-03 -1.312834e-03 -1.373021e-03
## ASV2900      5.830647e-03  6.059814e-03  6.296502e-03  6.540877e-03
## ASV3963     -5.863570e-03 -6.087861e-03 -6.319090e-03 -6.557386e-03
## ASV0041     -1.116384e-03 -1.168412e-03 -1.222783e-03 -1.279591e-03
## ASV1865      3.352056e-03  3.513976e-03  3.683587e-03  3.861228e-03
## ASV1140      1.861245e-03  1.948344e-03  2.039290e-03  2.134224e-03
## ASV1179      1.893464e-03  1.978888e-03  2.067928e-03  2.160716e-03
## ASV0279      2.848018e-03  2.973050e-03  3.103202e-03  3.238660e-03
## ASV0043     -5.350265e-04 -5.627043e-04 -5.918861e-04 -6.226577e-04
## ASV2097     -1.661783e-03 -1.730763e-03 -1.802347e-03 -1.876622e-03
## ASV0309     -3.323236e-04 -3.464466e-04 -3.611107e-04 -3.763329e-04
## ASV0607      4.526782e-03  4.733552e-03  4.949364e-03  5.174579e-03
## ASV0025     -1.263497e-03 -1.321662e-03 -1.382390e-03 -1.445785e-03
## ASV2284     -4.663305e-03 -4.848880e-03 -5.040691e-03 -5.238884e-03
## ASV0556      1.316715e-03  1.381210e-03  1.448840e-03  1.519749e-03
## ASV5040     -5.414941e-03 -5.765396e-03 -6.138494e-03 -6.535581e-03
## ASV2924     -1.477347e-02 -1.534114e-02 -1.592630e-02 -1.652924e-02
## ASV1331      3.982193e-03  4.160628e-03  4.346617e-03  4.540448e-03
## ASV0506     -1.635234e-03 -1.696841e-03 -1.760120e-03 -1.825065e-03
## ASV1514      6.030870e-03  6.300322e-03  6.580997e-03  6.873289e-03
## ASV2144      5.748017e-03  6.004733e-03  6.272243e-03  6.550946e-03
## ASV2265      3.789749e-03  3.959870e-03  4.137179e-03  4.321944e-03
## ASV5156      2.663194e-03  2.755174e-03  2.849045e-03  2.944756e-03
## ASV5534      7.732077e-04  7.953776e-04  8.175458e-04  8.396508e-04
## ASV5747     -1.523506e-03 -1.650432e-03 -1.787036e-03 -1.933948e-03
## ASV6657      2.861694e-03  2.980528e-03  3.103648e-03  3.231161e-03
## ASV0658     -2.083811e-03 -2.164907e-03 -2.248466e-03 -2.334509e-03
## ASV0716      3.847636e-03  4.009758e-03  4.177824e-03  4.351980e-03
## ASV1657      7.277711e-03  7.566268e-03  7.864058e-03  8.171214e-03
## ASV1885      5.943568e-03  6.155375e-03  6.371977e-03  6.593275e-03
## ASV2333      3.379207e-03  3.526573e-03  3.679824e-03  3.839153e-03
## ASV3375      2.562983e-03  2.667151e-03  2.774948e-03  2.886463e-03
## ASV4317      2.392041e-03  2.501408e-03  2.615658e-03  2.735006e-03
## ASV9599     -6.396863e-04 -6.929701e-04 -7.503154e-04 -8.119870e-04
## ASV0175     -3.642505e-03 -3.797916e-03 -3.959172e-03 -4.126426e-03
## ASV1032      1.498748e-03  1.557939e-03  1.619016e-03  1.682007e-03
## ASV1235      2.585447e-03  2.674098e-03  2.764363e-03  2.856154e-03
## ASV1262      3.782527e-03  3.948035e-03  4.120181e-03  4.299183e-03
## ASV1320      2.324540e-03  2.440348e-03  2.561989e-03  2.689750e-03
## ASV13797     2.167546e-03  2.260045e-03  2.356123e-03  2.455896e-03
## ASV1491      3.407068e-03  3.578157e-03  3.757714e-03  3.946118e-03
## ASV15014    -4.973009e-04 -5.387073e-04 -5.832679e-04 -6.311879e-04
## ASV1510      4.533850e-03  4.748237e-03  4.972408e-03  5.206760e-03
## ASV1551      1.502022e-02  1.569815e-02  1.640501e-02  1.714189e-02
## ASV1919      2.091420e-03  2.226309e-03  2.369880e-03  2.522636e-03
## ASV2114      2.660302e-03  2.770070e-03  2.883851e-03  3.001766e-03
## ASV21486    -4.268957e-04 -4.624220e-04 -5.006522e-04 -5.417622e-04
## ASV2448      2.782737e-03  2.900712e-03  3.023138e-03  3.150143e-03
## ASV2589      5.134807e-03  5.340598e-03  5.553261e-03  5.772934e-03
## ASV2608      3.548642e-03  3.701683e-03  3.860736e-03  4.025996e-03
## ASV2786      7.219533e-03  7.543257e-03  7.880960e-03  8.233225e-03
## ASV2827      2.496903e-03  2.602782e-03  2.712625e-03  2.826537e-03
## ASV2872      1.068939e-02  1.112683e-02  1.157923e-02  1.204688e-02
## ASV3125      2.083056e-03  2.168069e-03  2.256033e-03  2.347016e-03
## ASV3247      4.597029e-03  4.787272e-03  4.984297e-03  5.188265e-03
## ASV3451     -1.322807e-03 -1.432890e-03 -1.551352e-03 -1.678738e-03
## ASV3465     -6.405459e-05 -8.264880e-05 -1.032246e-04 -1.259363e-04
## ASV3809      6.160078e-03  6.411892e-03  6.672431e-03  6.941884e-03
## ASV4006      3.022355e-03  3.147787e-03  3.277696e-03  3.412188e-03
## ASV4046      4.439540e-03  4.623992e-03  4.815115e-03  5.013078e-03
## ASV4938      4.294591e-05  1.838714e-05 -9.153595e-06 -3.990864e-05
## ASV5435     -2.243854e-03 -2.430501e-03 -2.631345e-03 -2.847307e-03
## ASV5605      2.357390e-03  2.437507e-03  2.519021e-03  2.601846e-03
## ASV5635     -7.483214e-04 -8.105518e-04 -8.775135e-04 -9.495131e-04
## ASV5743      2.136903e-03  2.227760e-03  2.322084e-03  2.419981e-03
## ASV6627     -7.765849e-04 -8.411569e-04 -9.106370e-04 -9.853435e-04
## ASV6785     -8.643519e-04 -9.362082e-04 -1.013525e-03 -1.096655e-03
## ASV7368      2.725488e-03  2.848422e-03  2.976659e-03  3.110411e-03
## ASV9118      8.760576e-04  9.065925e-04  9.377937e-04  9.696497e-04
## ASV9135      1.565782e-03  1.614350e-03  1.663344e-03  1.712676e-03
## ASV9435      2.006673e-03  2.079419e-03  2.153887e-03  2.230047e-03
## ASV9671     -1.108223e-03 -1.200325e-03 -1.299423e-03 -1.405968e-03
## ASV0387     -3.663162e-03 -3.809318e-03 -3.960204e-03 -4.115890e-03
## ASV0454     -5.967970e-03 -6.213712e-03 -6.468042e-03 -6.731139e-03
## ASV0751     -1.633871e-03 -1.694601e-03 -1.756918e-03 -1.820813e-03
## ASV1081      3.740611e-03  3.905491e-03  4.077013e-03  4.255388e-03
## ASV1332      6.542162e-03  6.820991e-03  7.110324e-03  7.410445e-03
## ASV2659      7.401532e-03  7.730490e-03  8.072884e-03  8.429153e-03
## ASV2979      3.143491e-03  3.270684e-03  3.402122e-03  3.537876e-03
## ASV4184      4.315280e-03  4.473329e-03  4.635295e-03  4.801131e-03
## ASV6198      1.451442e-03  1.511163e-03  1.573081e-03  1.637268e-03
## ASV7454      1.539542e-03  1.601360e-03  1.665205e-03  1.731112e-03
## ASV8198      1.158298e-03  1.190960e-03  1.223529e-03  1.255901e-03
## ASV0855      4.034184e-03  4.213471e-03  4.400194e-03  4.594617e-03
## ASV10092     1.766766e-03  1.839059e-03  1.913892e-03  1.991325e-03
## ASV1532      3.691166e-03  3.863563e-03  4.043837e-03  4.232330e-03
## ASV2553      6.439936e-03  6.727136e-03  7.026334e-03  7.337967e-03
## ASV2741      9.052772e-03  9.476350e-03  9.919120e-03  1.038188e-02
## ASV4095      5.557907e-03  5.828758e-03  6.112448e-03  6.409515e-03
## ASV5295      1.724133e-03  1.788752e-03  1.855109e-03  1.923197e-03
## ASV5787     -4.555214e-04 -4.933540e-04 -5.340571e-04 -5.778160e-04
## ASV9455      2.421424e-03  2.523484e-03  2.629408e-03  2.739316e-03
## ASV10879     2.246121e-03  2.343742e-03  2.445301e-03  2.550941e-03
## ASV3997      3.071093e-03  3.217666e-03  3.370993e-03  3.531349e-03
## ASV6760      5.995923e-04  6.057773e-04  6.106746e-04  6.141360e-04
## ASV6990      2.239613e-03  2.330707e-03  2.424980e-03  2.522510e-03
## ASV9560      1.383669e-03  1.436219e-03  1.490323e-03  1.546002e-03
## ASV0220     -3.488364e-04 -3.641089e-04 -3.799967e-04 -3.965202e-04
## ASV2518      1.469253e-03  1.534897e-03  1.603287e-03  1.674525e-03
## ASV3615      3.648272e-03  3.806076e-03  3.970081e-03  4.140483e-03
## ASV0075     -1.718720e-05 -1.835684e-05 -1.960227e-05 -2.092768e-05
## ASV8070      8.540533e-05  8.143030e-05  7.670168e-05  7.115293e-05
## ASV1658      1.409938e-03  1.467507e-03  1.527079e-03  1.588700e-03
## ASV0773      2.627639e-03  2.737673e-03  2.851746e-03  2.969965e-03
## ASV0799      2.654282e-04  2.736307e-04  2.818504e-04  2.900596e-04
## ASV1839     -1.833367e-03 -1.911228e-03 -1.991964e-03 -2.075642e-03
## ASV0265      2.255275e-03  2.361810e-03  2.473276e-03  2.589890e-03
## ASV3741      7.377352e-04  7.657429e-04  7.944714e-04  8.239062e-04
## ASV0847      3.014587e-03  3.149687e-03  3.290480e-03  3.437175e-03
## ASV1026      3.905723e-03  4.076004e-03  4.253029e-03  4.437006e-03
## ASV1222     -9.147652e-04 -9.435290e-04 -9.726041e-04 -1.001943e-03
## ASV0729     -6.516942e-05 -6.823403e-05 -7.144235e-05 -7.480120e-05
## ASV0143     -9.604446e-04 -1.000189e-03 -1.041354e-03 -1.083975e-03
## ASV1328      5.429721e-04  5.721737e-04  6.030015e-04  6.355444e-04
## ASV9078     -1.275654e-03 -1.348113e-03 -1.424797e-03 -1.505943e-03
## ASV0027     -1.189051e-03 -1.243580e-03 -1.300494e-03 -1.359885e-03
## ASV0546     -1.297654e-03 -1.350297e-03 -1.404764e-03 -1.461102e-03
## ASV1136      3.272288e-03  3.417341e-03  3.568419e-03  3.725741e-03
## ASV3081      1.732347e-03  1.810664e-03  1.892405e-03  1.977716e-03
## ASV0531      5.744485e-04  6.054137e-04  6.381045e-04  6.726166e-04
## ASV2525      2.494571e-03  2.599424e-03  2.708149e-03  2.820846e-03
## ASV1083     -4.501999e-04 -4.648730e-04 -4.797682e-04 -4.948701e-04
## ASV0424     -3.727902e-04 -3.899386e-04 -4.078390e-04 -4.265204e-04
## ASV0644      3.198468e-04  3.464080e-04  3.749840e-04  4.057052e-04
## ASV6007     -3.215046e-04 -3.484111e-04 -3.773884e-04 -4.085743e-04
## ASV0564      1.255724e-03  1.314919e-03  1.376814e-03  1.441520e-03
## ASV1938      3.559876e-03  3.695740e-03  3.835467e-03  3.979064e-03
## ASV6516     -6.008336e-03 -6.279946e-03 -6.563247e-03 -6.858698e-03
## ASV0503     -2.236647e-03 -2.323712e-03 -2.413408e-03 -2.505755e-03
## ASV6913     -1.175031e-02 -1.226371e-02 -1.279811e-02 -1.335430e-02
## ASV0164     -1.502847e-03 -1.572068e-03 -1.644372e-03 -1.719887e-03
## ASV1576      4.175353e-03  4.359995e-03  4.552351e-03  4.752716e-03
## ASV1725      2.168758e-03  2.273193e-03  2.382522e-03  2.496955e-03
## ASV4501      9.862279e-04  1.018949e-03  1.052134e-03  1.085732e-03
## ASV10678    -5.516228e-03 -5.763505e-03 -6.021221e-03 -6.289764e-03
## ASV0944      9.046954e-04  9.481923e-04  9.937871e-04  1.041581e-03
## ASV2292      4.374930e-03  4.562622e-03  4.757534e-03  4.959880e-03
## ASV1090      1.773182e-03  1.850503e-03  1.930930e-03  2.014567e-03
## ASV9117     -1.102384e-03 -1.139756e-03 -1.177852e-03 -1.216645e-03
## ASV0285     -2.415817e-03 -2.545638e-03 -2.682577e-03 -2.827009e-03
## ASV0463     -1.191591e-03 -1.238219e-03 -1.286245e-03 -1.335674e-03
## ASV3199      1.498793e-03  1.556413e-03  1.615717e-03  1.676713e-03
## ASV0150     -2.921513e-04 -3.083252e-04 -3.254071e-04 -3.434447e-04
## ASV6583     -1.248723e-03 -1.296997e-03 -1.346881e-03 -1.398425e-03
## ASV0392      1.194419e-04  1.234176e-04  1.274483e-04  1.315277e-04
## ASV14007    -1.959047e-03 -2.042478e-03 -2.129037e-03 -2.218806e-03
## ASV0177     -9.146054e-04 -9.529555e-04 -9.927024e-04 -1.033880e-03
## ASV6448     -1.621410e-03 -1.707615e-03 -1.798485e-03 -1.894263e-03
## ASV5399     -9.422246e-03 -9.885436e-03 -1.037132e-02 -1.088094e-02
## ASV0277     -1.985694e-04 -2.063941e-04 -2.144329e-04 -2.226805e-04
## ASV2599      6.254148e-04  6.109776e-04  5.928725e-04  5.707804e-04
## ASV13465    -5.243595e-04 -5.370967e-04 -5.496043e-04 -5.618266e-04
## ASV2412      5.239066e-04  5.475819e-04  5.722744e-04  5.980236e-04
## ASV0423     -1.418506e-04 -1.439379e-04 -1.457357e-04 -1.472007e-04
## ASV5187      2.384632e-03  2.464220e-03  2.545189e-03  2.627465e-03
## ASV0701     -1.798853e-03 -1.881203e-03 -1.967173e-03 -2.056909e-03
## ASV4248      1.035072e-03  1.087141e-03  1.141827e-03  1.199252e-03
## ASV0519      1.721180e-03  1.801663e-03  1.885782e-03  1.973687e-03
## ASV0764      4.605121e-04  4.824342e-04  5.053644e-04  5.293435e-04
## ASV5385     -1.528919e-03 -1.600086e-03 -1.674499e-03 -1.752302e-03
## ASV3021     -2.319610e-03 -2.403789e-03 -2.490144e-03 -2.578677e-03
## ASV4119     -6.584631e-03 -6.877025e-03 -7.181822e-03 -7.499523e-03
## ASV2534     -3.701566e-04 -3.944606e-04 -4.203538e-04 -4.479318e-04
## ASV1061      1.805934e-03  1.898381e-03  1.995705e-03  2.098165e-03
## ASV0670     -4.519732e-04 -4.723571e-04 -4.936037e-04 -5.157440e-04
## ASV1384      2.071653e-03  2.174295e-03  2.281949e-03  2.394841e-03
## ASV1981      4.826269e-03  5.051273e-03  5.286455e-03  5.532241e-03
## ASV9632     -7.688287e-04 -7.866573e-04 -8.041029e-04 -8.210889e-04
## ASV4564      1.394626e-03  1.457312e-03  1.522618e-03  1.590634e-03
## ASV5289     -9.268308e-04 -9.735913e-04 -1.022798e-03 -1.074585e-03
## ASV0516      3.290233e-03  3.437307e-03  3.590506e-03  3.750044e-03
## ASV1463     -4.606921e-03 -4.812525e-03 -5.026743e-03 -5.249890e-03
## ASV0969      1.613394e-04  1.670138e-04  1.727850e-04  1.786437e-04
## ASV1113     -1.058503e-03 -1.106368e-03 -1.156288e-03 -1.208344e-03
## ASV1234     -1.434775e-03 -1.514477e-03 -1.598915e-03 -1.688384e-03
## ASV3814     -1.052769e-03 -1.124252e-03 -1.200523e-03 -1.281871e-03
## ASV1000      2.059614e-03  2.147406e-03  2.238488e-03  2.332947e-03
## ASV0079     -2.595152e-04 -2.739818e-04 -2.892928e-04 -3.054976e-04
## ASV0145      3.257611e-04  3.351655e-04  3.446012e-04  3.540478e-04
## ASV0457     -2.700688e-03 -2.817809e-03 -2.939535e-03 -3.066010e-03
## ASV1485      2.307230e-04  2.421867e-04  2.542350e-04  2.668986e-04
## ASV0535      9.136134e-04  9.614038e-04  1.011724e-03  1.064702e-03
## ASV0259     -1.520649e-03 -1.587656e-03 -1.657356e-03 -1.729832e-03
## ASV0570      5.054703e-04  5.313894e-04  5.586781e-04  5.874099e-04
## ASV0906      1.709802e-03  1.782067e-03  1.857010e-03  1.934701e-03
## ASV1748      1.321978e-03  1.346994e-03  1.370258e-03  1.391488e-03
## ASV5520     -2.533371e-03 -2.665934e-03 -2.805510e-03 -2.952451e-03
## ASV2288     -5.791010e-03 -6.050991e-03 -6.321977e-03 -6.604379e-03
## ASV1887     -1.380649e-03 -1.458635e-03 -1.540971e-03 -1.627873e-03
## ASV0374     -2.117430e-04 -2.185115e-04 -2.253628e-04 -2.322867e-04
## ASV0823      3.266715e-03  3.403128e-03  3.544554e-03  3.691129e-03
## ASV0717      2.543334e-04  2.658940e-04  2.779505e-04  2.905214e-04
## ASV0431     -7.029724e-04 -7.360576e-04 -7.706735e-04 -8.068879e-04
## ASV1030      8.060682e-03  8.438965e-03  8.834619e-03  9.248401e-03
## ASV1082     -1.038739e-03 -1.086436e-03 -1.136237e-03 -1.188227e-03
## ASV2684      2.502948e-04  2.686697e-04  2.882322e-04  3.090384e-04
## ASV0051      9.889201e-04  1.034283e-03  1.081658e-03  1.131131e-03
## ASV0513     -2.915714e-04 -3.031002e-04 -3.149749e-04 -3.271957e-04
## ASV0581      1.794538e-03  1.875704e-03  1.960329e-03  2.048541e-03
## ASV7282      6.801691e-04  7.203413e-04  7.630480e-04  8.084551e-04
## ASV3009     -1.532742e-03 -1.601892e-03 -1.673989e-03 -1.749143e-03
## ASV2106      2.035318e-03  2.146642e-03  2.264270e-03  2.388559e-03
## ASV1012      1.318869e-03  1.380304e-03  1.444468e-03  1.511468e-03
## ASV0921      1.356882e-03  1.422898e-03  1.492168e-03  1.564857e-03
## ASV0010     -7.741178e-04 -8.096740e-04 -8.467925e-04 -8.855348e-04
## ASV1178      3.601927e-04  3.773349e-04  3.952472e-04  4.139567e-04
## ASV2848     -2.015023e-03 -2.102928e-03 -2.194429e-03 -2.289661e-03
## ASV0586      5.216826e-03  5.463022e-03  5.720722e-03  5.990452e-03
## ASV4225     -6.370836e-03 -6.554665e-03 -6.739334e-03 -6.924496e-03
## ASV2156     -2.907918e-03 -3.042837e-03 -3.183845e-03 -3.331201e-03
## ASV9778     -2.071356e-03 -2.165805e-03 -2.264382e-03 -2.367251e-03
## ASV0493     -4.136703e-03 -4.316998e-03 -4.504547e-03 -4.699600e-03
## ASV3770     -6.634828e-04 -7.065512e-04 -7.524086e-04 -8.012210e-04
## ASV0470      2.954202e-03  3.088855e-03  3.229398e-03  3.376070e-03
## ASV0262     -1.355699e-03 -1.425798e-03 -1.499589e-03 -1.577263e-03
## ASV0998      7.799591e-04  8.163863e-04  8.544808e-04  8.943159e-04
## ASV7708     -3.449005e-04 -3.579563e-04 -3.713455e-04 -3.850612e-04
## ASV0453     -3.019021e-04 -3.156628e-04 -3.300530e-04 -3.451037e-04
## ASV0044      1.226019e-03  1.280876e-03  1.338034e-03  1.397576e-03
## ASV5490      6.568887e-04  6.817913e-04  7.073003e-04  7.333939e-04
## ASV2638     -3.764433e-04 -3.910023e-04 -4.061010e-04 -4.217689e-04
## ASV0829      4.213756e-03  4.399453e-03  4.592451e-03  4.792947e-03
## ASV0601      1.453965e-03  1.523276e-03  1.595858e-03  1.671861e-03
## ASV0234      1.181367e-04  1.244741e-04  1.311754e-04  1.382630e-04
## ASV0133      2.165278e-03  2.263919e-03  2.366851e-03  2.474243e-03
## ASV0323      7.351422e-04  7.710090e-04  8.086542e-04  8.481673e-04
## ASV0854     -4.867441e-04 -5.084070e-04 -5.309718e-04 -5.544710e-04
## ASV0110      1.371110e-03  1.434229e-03  1.500159e-03  1.569016e-03
## ASV0816     -1.380276e-04 -1.445708e-04 -1.514174e-04 -1.585807e-04
## ASV1031     -4.799602e-04 -4.994757e-04 -5.196863e-04 -5.406123e-04
## ASV0144     -6.441872e-04 -6.749998e-04 -7.072956e-04 -7.411468e-04
## ASV0020     -3.098701e-04 -3.256382e-04 -3.422463e-04 -3.597416e-04
## ASV0962     -8.026453e-04 -8.384166e-04 -8.756679e-04 -9.144501e-04
## ASV0794      1.583866e-03  1.662058e-03  1.744084e-03  1.830120e-03
## ASV7117     -1.388149e-03 -1.448802e-03 -1.511887e-03 -1.577485e-03
## ASV1008     -7.027269e-04 -7.366014e-04 -7.721125e-04 -8.093384e-04
## ASV0096      1.753692e-03  1.834270e-03  1.918420e-03  2.006289e-03
## ASV0128     -2.946784e-03 -3.087522e-03 -3.234974e-03 -3.389459e-03
## ASV5232      2.745218e-03  2.878740e-03  3.018735e-03  3.165504e-03
## ASV0031     -2.081735e-04 -2.179030e-04 -2.280726e-04 -2.387005e-04
## ASV1744     -2.840924e-03 -2.975446e-03 -3.116401e-03 -3.264109e-03
## ASV0289      7.889322e-04  8.250900e-04  8.628517e-04  9.022845e-04
## ASV7413     -5.462372e-04 -5.795004e-04 -6.148449e-04 -6.523950e-04
## ASV0822     -3.386006e-03 -3.531423e-03 -3.682446e-03 -3.839242e-03
## ASV8111     -5.609020e-03 -5.852529e-03 -6.105900e-03 -6.369492e-03
## ASV0687      7.653424e-04  8.016718e-04  8.396869e-04  8.794604e-04
## ASV0112     -2.810171e-04 -2.945442e-04 -3.087197e-04 -3.235740e-04
## ASV0987      9.511953e-04  9.970357e-04  1.045096e-03  1.095483e-03
## ASV5332     -4.636380e-04 -4.760319e-04 -4.885107e-04 -5.010713e-04
## ASV1129     -1.706907e-03 -1.785599e-03 -1.867825e-03 -1.953735e-03
## ASV1274     -4.680896e-04 -4.892807e-04 -5.113869e-04 -5.344442e-04
## ASV0119      1.136039e-03  1.188123e-03  1.242506e-03  1.299283e-03
## ASV0890     -6.588919e-05 -6.957796e-05 -7.350576e-05 -7.769103e-05
## ASV0848     -2.109256e-03 -2.205969e-03 -2.306963e-03 -2.412414e-03
## ASV5944     -9.145864e-03 -9.553051e-03 -9.977196e-03 -1.041891e-02
## ASV19741    -3.349201e-03 -3.499674e-03 -3.656538e-03 -3.820036e-03
## ASV0504     -4.142111e-03 -4.321041e-03 -4.507012e-03 -4.700253e-03
## ASV2146     -2.941441e-03 -3.064397e-03 -3.191935e-03 -3.324189e-03
## ASV0089     -7.149220e-04 -7.471129e-04 -7.806632e-04 -8.156218e-04
## ASV2301     -1.177370e-03 -1.232151e-03 -1.289414e-03 -1.349265e-03
## ASV2982     -1.805085e-02 -1.868050e-02 -1.932469e-02 -1.998331e-02
## ASV0891     -1.356696e-03 -1.418193e-03 -1.482342e-03 -1.549247e-03
## ASV0093      1.473826e-03  1.539871e-03  1.608705e-03  1.680432e-03
## ASV0042      5.227475e-04  5.467697e-04  5.718603e-04  5.980640e-04
## ASV0980      1.609248e-03  1.675365e-03  1.743729e-03  1.814375e-03
## ASV0069     -7.969778e-04 -8.334189e-04 -8.714519e-04 -9.111393e-04
## ASV1364     -6.004076e-04 -6.268555e-04 -6.543752e-04 -6.830023e-04
## ASV0524     -3.101972e-03 -3.247311e-03 -3.399335e-03 -3.558341e-03
## ASV0435      4.223814e-03  4.419319e-03  4.623617e-03  4.837083e-03
## ASV0517     -8.311665e-04 -8.694180e-04 -9.093727e-04 -9.511018e-04
## ASV3167     -6.384768e-03 -6.711410e-03 -7.055028e-03 -7.416487e-03
## ASV4280     -3.779288e-03 -3.951333e-03 -4.130899e-03 -4.318291e-03
## ASV1158      1.426567e-03  1.497903e-03  1.572704e-03  1.651116e-03
## ASV2214      1.229010e-03  1.282537e-03  1.338348e-03  1.396549e-03
## ASV0544     -2.100750e-03 -2.200650e-03 -2.305272e-03 -2.414837e-03
## ASV5326     -2.987778e-04 -3.135311e-04 -3.290364e-04 -3.453342e-04
## ASV3765     -1.593868e-03 -1.665772e-03 -1.740739e-03 -1.818884e-03
## ASV4646     -8.805659e-05 -1.005860e-04 -1.142765e-04 -1.292114e-04
## ASV0090      1.119325e-04  1.158487e-04  1.198319e-04  1.238762e-04
## ASV3680      2.511136e-03  2.613140e-03  2.718548e-03  2.827413e-03
## ASV0111      2.686795e-04  2.800499e-04  2.918415e-04  3.040651e-04
## ASV0768      4.137166e-04  4.340115e-04  4.553227e-04  4.777026e-04
## ASV4862     -1.823515e-04 -1.862959e-04 -1.900070e-04 -1.934379e-04
## ASV1742     -2.283629e-03 -2.383550e-03 -2.487536e-03 -2.595732e-03
## ASV3701     -7.816083e-04 -8.100623e-04 -8.392473e-04 -8.691603e-04
## ASV2386     -4.501103e-03 -4.710974e-03 -4.930292e-03 -5.159440e-03
## ASV0375     -3.086255e-03 -3.222342e-03 -3.364056e-03 -3.511604e-03
## ASV2796      1.022633e-03  1.064295e-03  1.107462e-03  1.152183e-03
## ASV1369      2.345725e-03  2.446505e-03  2.551434e-03  2.660687e-03
## ASV10272    -3.524967e-03 -3.682837e-03 -3.847307e-03 -4.018611e-03
## ASV10354    -5.248743e-03 -5.483766e-03 -5.728610e-03 -5.983623e-03
## ASV1067      1.706487e-03  1.781952e-03  1.860528e-03  1.942327e-03
## ASV1900      2.865945e-03  2.998472e-03  3.136943e-03  3.281609e-03
## ASV4079     -1.371837e-03 -1.440690e-03 -1.513020e-03 -1.588995e-03
## ASV4149      5.340308e-03  5.561520e-03  5.790527e-03  6.027494e-03
## ASV5140     -5.248016e-03 -5.482969e-03 -5.727738e-03 -5.982667e-03
## ASV10782     2.644692e-04  2.843034e-04  3.057290e-04  3.288763e-04
## ASV4273     -4.253645e-04 -4.373544e-04 -4.491686e-04 -4.607349e-04
## ASV8121      2.381970e-03  2.490689e-03  2.604197e-03  2.722694e-03
## ASV8438     -5.970233e-03 -6.237491e-03 -6.515911e-03 -6.805889e-03
## ASV9390     -5.969059e-03 -6.236209e-03 -6.514513e-03 -6.804364e-03
## ASV1340      4.888630e-03  5.114460e-03  5.350379e-03  5.596803e-03
## ASV2650     -1.102880e-02 -1.151668e-02 -1.202444e-02 -1.255276e-02
## ASV4674      2.946403e-03  3.076983e-03  3.212906e-03  3.354350e-03
## ASV10492     1.752610e-05  1.554674e-05  1.322992e-05  1.054005e-05
## ASV11430    -4.554316e-03 -4.758095e-03 -4.970376e-03 -5.191460e-03
## ASV12135    -4.553421e-03 -4.757118e-03 -4.969311e-03 -5.190297e-03
## ASV14970    -5.598821e-03 -5.849232e-03 -6.110083e-03 -6.381740e-03
## ASV1954      6.825789e-03  7.133374e-03  7.454020e-03  7.788210e-03
## ASV2613      4.292830e-03  4.484262e-03  4.683669e-03  4.891336e-03
## ASV2757      2.577679e-03  2.685069e-03  2.796311e-03  2.911495e-03
## ASV2909     -8.209653e-03 -8.595532e-03 -8.999281e-03 -9.421701e-03
## ASV2954     -3.028580e-04 -3.165039e-04 -3.307202e-04 -3.455266e-04
## ASV2969      2.085127e-03  2.181922e-03  2.283093e-03  2.388828e-03
## ASV3410      7.525953e-04  7.888375e-04  8.268465e-04  8.667106e-04
## ASV3575      1.370305e-03  1.430412e-03  1.492975e-03  1.558083e-03
## ASV4275      3.459975e-03  3.606421e-03  3.758285e-03  3.915702e-03
## ASV4652      7.888900e-04  8.262549e-04  8.653728e-04  9.063235e-04
## ASV4761      2.500585e-03  2.605603e-03  2.714406e-03  2.827074e-03
## ASV6003      1.968563e-03  2.063741e-03  2.163566e-03  2.268265e-03
## ASV6110     -1.285004e-02 -1.342501e-02 -1.402397e-02 -1.464777e-02
## ASV7427      2.199849e-03  2.295627e-03  2.395197e-03  2.498678e-03
## ASV8092     -4.213483e-03 -4.401987e-03 -4.598355e-03 -4.802863e-03
## ASV8169     -1.284584e-02 -1.342042e-02 -1.401896e-02 -1.464231e-02
## ASV9693      2.169903e-03  2.266105e-03  2.366239e-03  2.470437e-03
## ASV10913     1.494200e-03  1.563752e-03  1.636464e-03  1.712469e-03
## ASV1979      1.269186e-03  1.323671e-03  1.380216e-03  1.438872e-03
## ASV3772      2.622808e-03  2.735929e-03  2.853457e-03  2.975528e-03
## ASV0113     -3.657443e-04 -3.826773e-04 -4.003649e-04 -4.188378e-04
## ASV1800     -4.852457e-04 -5.077778e-04 -5.313026e-04 -5.558573e-04
## ASV2335     -9.777860e-03 -1.021043e-02 -1.066110e-02 -1.113055e-02
## ASV0692     -7.163793e-05 -7.533481e-05 -7.924036e-05 -8.336824e-05
## ASV1120      3.675647e-04  3.850625e-04  4.033940e-04  4.225989e-04
## ASV1434     -1.793092e-03 -1.875497e-03 -1.961557e-03 -2.051424e-03
## ASV0076     -8.375533e-04 -8.757612e-04 -9.156304e-04 -9.572253e-04
## ASV0361      3.010353e-03  3.149606e-03  3.295117e-03  3.447151e-03
## ASV2231     -1.025378e-03 -1.077617e-03 -1.132610e-03 -1.190506e-03
## ASV2018     -2.406810e-04 -2.517458e-04 -2.633073e-04 -2.753872e-04
## ASV1529      1.325159e-03  1.388282e-03  1.454403e-03  1.523662e-03
## ASV0841     -4.476168e-04 -4.676744e-04 -4.885774e-04 -5.103570e-04
## ASV2556     -8.281672e-03 -8.658315e-03 -9.051264e-03 -9.461150e-03
## ASV2777      2.563813e-03  2.665325e-03  2.769980e-03  2.877803e-03
## ASV0355      2.059298e-03  2.152713e-03  2.250172e-03  2.351835e-03
## ASV5169     -2.452296e-03 -2.562420e-03 -2.677178e-03 -2.796739e-03
## ASV3091      2.362360e-03  2.473165e-03  2.589088e-03  2.710359e-03
## ASV2435      9.303612e-04  9.718148e-04  1.014983e-03  1.059925e-03
## ASV6822     -5.047683e-03 -5.273657e-03 -5.509071e-03 -5.754260e-03
## ASV12605    -4.986020e-03 -5.215654e-03 -5.455491e-03 -5.705951e-03
## ASV0286     -1.186671e-03 -1.240673e-03 -1.297062e-03 -1.355942e-03
## ASV0074     -4.751205e-04 -4.971437e-04 -5.201539e-04 -5.441919e-04
## ASV2485     -2.323420e-04 -2.462211e-04 -2.610338e-04 -2.768492e-04
## ASV1233     -3.752156e-03 -3.925929e-03 -4.107552e-03 -4.297365e-03
## ASV0356     -9.705854e-04 -1.013620e-03 -1.058454e-03 -1.105158e-03
## ASV2918     -4.114031e-03 -4.298820e-03 -4.491451e-03 -4.692219e-03
## ASV1427     -5.437438e-04 -5.707752e-04 -5.992010e-04 -6.290973e-04
## ASV1409      9.366843e-04  9.813294e-04  1.028096e-03  1.077083e-03
## ASV0770      2.733634e-04  2.845965e-04  2.962073e-04  3.082006e-04
## ASV1403     -2.544135e-03 -2.659239e-03 -2.779286e-03 -2.904465e-03
## ASV0314     -8.621889e-04 -8.993243e-04 -9.378662e-04 -9.778494e-04
## ASV0187     -2.662669e-04 -2.788503e-04 -2.920048e-04 -3.057532e-04
## ASV0313     -1.237453e-03 -1.292000e-03 -1.348750e-03 -1.407778e-03
## ASV1087      2.894461e-03  3.026003e-03  3.163253e-03  3.306435e-03
## ASV1970     -4.368079e-04 -4.563092e-04 -4.766148e-04 -4.977513e-04
## ASV0754      3.202246e-03  3.349220e-03  3.502698e-03  3.662949e-03
## ASV3775     -7.717962e-04 -8.077852e-04 -8.454168e-04 -8.847631e-04
## ASV0132     -5.507313e-04 -5.758772e-04 -6.021242e-04 -6.295164e-04
## ASV2329      1.787623e-04  1.768096e-04  1.740351e-04  1.703609e-04
## ASV0561      7.748120e-04  8.066336e-04  8.395030e-04  8.734284e-04
## ASV0130     -1.667249e-03 -1.743571e-03 -1.823238e-03 -1.906383e-03
## ASV0226      2.084463e-03  2.178427e-03  2.276383e-03  2.378479e-03
## ASV12648    -2.888442e-03 -3.016310e-03 -3.149532e-03 -3.288313e-03
## ASV0204      2.006380e-03  2.096863e-03  2.191195e-03  2.289518e-03
## ASV0767     -1.021209e-03 -1.071746e-03 -1.124859e-03 -1.180685e-03
## ASV0335     -1.861308e-03 -1.944594e-03 -2.031354e-03 -2.121708e-03
## ASV5901     -3.931670e-04 -4.097182e-04 -4.269081e-04 -4.447590e-04
## ASV0596      3.136718e-05  3.561200e-05  4.029224e-05  4.544674e-05
## ASV9271      1.629068e-03  1.712240e-03  1.799667e-03  1.891556e-03
## ASV0904      1.239166e-03  1.297640e-03  1.358840e-03  1.422887e-03
## ASV15270    -8.705656e-04 -9.160382e-04 -9.638734e-04 -1.014182e-03
## ASV0990     -6.808553e-04 -7.126488e-04 -7.458979e-04 -7.806665e-04
## ASV0155     -1.392953e-03 -1.456160e-03 -1.522090e-03 -1.590848e-03
## ASV0086     -2.787658e-04 -2.914963e-04 -3.047832e-04 -3.186486e-04
## ASV2581     -1.232351e-04 -1.277861e-04 -1.324285e-04 -1.371549e-04
## ASV1579     -1.167147e-03 -1.222600e-03 -1.280667e-03 -1.341468e-03
## ASV7730     -1.125863e-04 -1.211699e-04 -1.302993e-04 -1.399951e-04
## ASV0897      1.789506e-04  1.878000e-04  1.970951e-04  2.068587e-04
## ASV1975      7.816103e-03  8.172738e-03  8.545004e-03  8.933533e-03
##                                                                           
## (Intercept)  2.901324e-02  3.032080e-02  3.168352e-02  3.310335e-02 ......
## ASV1236      4.526499e-03  4.718001e-03  4.916573e-03  5.122392e-03 ......
## ASV0421     -2.121125e-03 -2.209272e-03 -2.300528e-03 -2.394956e-03 ......
## ASV0691     -4.173169e-03 -4.333385e-03 -4.498166e-03 -4.667518e-03 ......
## ASV0899      2.756343e-03  2.881879e-03  3.012770e-03  3.149207e-03 ......
## ASV1004      1.024236e-02  1.067926e-02  1.113259e-02  1.160279e-02 ......
## ASV1041     -6.314506e-03 -6.587501e-03 -6.871013e-03 -7.165334e-03 ......
## ASV1058      6.387781e-03  6.660975e-03  6.944545e-03  7.238776e-03 ......
## ASV12542     2.365877e-03  2.463861e-03  2.565320e-03  2.670334e-03 ......
## ASV1294      5.397677e-03  5.630362e-03  5.872031e-03  6.122944e-03 ......
## ASV13113     2.040563e-03  2.138589e-03  2.241353e-03  2.349087e-03 ......
## ASV1318      5.897235e-03  6.150277e-03  6.412969e-03  6.685578e-03 ......
## ASV2269     -1.007750e-02 -1.051291e-02 -1.096495e-02 -1.143408e-02 ......
## ASV2542      4.588416e-03  4.799222e-03  5.019351e-03  5.249185e-03 ......
## ASV2660     -4.437679e-03 -4.626331e-03 -4.821992e-03 -5.024836e-03 ......
## ASV2737      7.503288e-04  7.772107e-04  8.047214e-04  8.328509e-04 ......
## ASV2840      5.495660e-03  5.723604e-03  5.959534e-03  6.203607e-03 ......
## ASV3053      4.673912e-02  4.871533e-02  5.076475e-02  5.288926e-02 ......
## ASV3077      1.643525e-03  1.712968e-03  1.785005e-03  1.859709e-03 ......
## ASV3134      3.344869e-03  3.501843e-03  3.666079e-03  3.837904e-03 ......
## ASV3140      3.982430e-03  4.161176e-03  4.347380e-03  4.541299e-03 ......
## ASV3579      1.365674e-03  1.432550e-03  1.502756e-03  1.576459e-03 ......
## ASV6119     -2.749974e-03 -2.868756e-03 -2.992074e-03 -3.120050e-03 ......
## ASV7557     -5.593174e-03 -5.834706e-03 -6.085458e-03 -6.345676e-03 ......
## ASV8422      1.177424e-03  1.224659e-03  1.273475e-03  1.323903e-03 ......
## ASV1086     -2.754684e-04 -2.862134e-04 -2.973073e-04 -3.087576e-04 ......
## ASV1310      2.364030e-03  2.464846e-03  2.569452e-03  2.677949e-03 ......
## ASV15750    -3.985668e-04 -4.147734e-04 -4.314874e-04 -4.487097e-04 ......
## ASV16905    -1.148211e-03 -1.197791e-03 -1.249265e-03 -1.302680e-03 ......
## ASV2033      5.185865e-03  5.421704e-03  5.667753e-03  5.924407e-03 ......
## ASV2089      2.105082e-03  2.196355e-03  2.291132e-03  2.389508e-03 ......
## ASV2127      7.865800e-03  8.201127e-03  8.549081e-03  8.909998e-03 ......
## ASV2725      6.224933e-03  6.484083e-03  6.752463e-03  7.030275e-03 ......
## ASV2804     -2.377848e-03 -2.480518e-03 -2.587106e-03 -2.697717e-03 ......
## ASV3075      5.333323e-03  5.565314e-03  5.806554e-03  6.057350e-03 ......
## ASV3327      7.448020e-03  7.785982e-03  8.138566e-03  8.506342e-03 ......
## ASV3342      6.098344e-03  6.371362e-03  6.655781e-03  6.952005e-03 ......
## ASV3532     -6.959056e-03 -7.272066e-03 -7.598272e-03 -7.938152e-03 ......
## ASV3600      3.104516e-03  3.241881e-03  3.384899e-03  3.533768e-03 ......
## ASV4013      5.926445e-03  6.182379e-03  6.448242e-03  6.724324e-03 ......
## ASV4136      6.404515e-03  6.671716e-03  6.948490e-03  7.235055e-03 ......
## ASV4195      2.403139e-02  2.506873e-02  2.614564e-02  2.726316e-02 ......
## ASV4407     -9.398759e-03 -9.804370e-03 -1.022544e-02 -1.066239e-02 ......
## ASV4717      7.919097e-04  8.168037e-04  8.419958e-04  8.674534e-04 ......
## ASV6794      3.520116e-03  3.659714e-03  3.803791e-03  3.952416e-03 ......
## ASV8324     -4.814285e-03 -5.022031e-03 -5.237694e-03 -5.461485e-03 ......
## ASV8981     -1.432345e-04 -1.472771e-04 -1.512609e-04 -1.551627e-04 ......
## ASV9859      1.603446e-03  1.685148e-03  1.771217e-03  1.861902e-03 ......
## ASV0936      4.251269e-04  4.471028e-04  4.701868e-04  4.944281e-04 ......
## ASV12683    -1.423508e-04 -1.502377e-04 -1.585356e-04 -1.672612e-04 ......
## ASV1293      2.995195e-03  3.122209e-03  3.253938e-03  3.390501e-03 ......
## ASV13055    -1.417959e-04 -1.457618e-04 -1.496425e-04 -1.534094e-04 ......
## ASV17063    -2.494777e-03 -2.602373e-03 -2.714066e-03 -2.829964e-03 ......
## ASV2228      2.030759e-03  2.118322e-03  2.209217e-03  2.303532e-03 ......
## ASV2769      2.196802e-04  2.307171e-04  2.423359e-04  2.545678e-04 ......
## ASV2803      1.723592e-03  1.791711e-03  1.861985e-03  1.934441e-03 ......
## ASV2896      1.725959e-03  1.804050e-03  1.885546e-03  1.970591e-03 ......
## ASV3062      1.908483e-03  1.998911e-03  2.093596e-03  2.192733e-03 ......
## ASV3107      3.462756e-03  3.619337e-03  3.782659e-03  3.952984e-03 ......
## ASV3265      4.622844e-03  4.819045e-03  5.022555e-03  5.233566e-03 ......
## ASV3666      1.121926e-05  1.141743e-05  1.162055e-05  1.183004e-05 ......
## ASV4497      1.417752e-03  1.479046e-03  1.542750e-03  1.608940e-03 ......
## ASV6914     -3.691388e-04 -3.873922e-04 -4.065284e-04 -4.265864e-04 ......
## ASV0576     -5.778777e-03 -6.010588e-03 -6.249944e-03 -6.496955e-03 ......
## ASV0673      4.533430e-03  4.735923e-03  4.946834e-03  5.166457e-03 ......
## ASV0772      2.577311e-03  2.689492e-03  2.806145e-03  2.927416e-03 ......
## ASV0862     -3.398753e-04 -3.483989e-04 -3.567517e-04 -3.648882e-04 ......
## ASV0898      1.950125e-03  2.040716e-03  2.135360e-03  2.234220e-03 ......
## ASV0910      2.381606e-03  2.490331e-03  2.603809e-03  2.722229e-03 ......
## ASV0964     -2.348254e-03 -2.446477e-03 -2.548270e-03 -2.653721e-03 ......
## ASV10059     1.735196e-03  1.818573e-03  1.905992e-03  1.997651e-03 ......
## ASV10263    -3.803428e-03 -3.967682e-03 -4.138211e-03 -4.315182e-03 ......
## ASV1088      3.821223e-03  3.995394e-03  4.177243e-03  4.367095e-03 ......
## ASV1101      4.389926e-03  4.577313e-03  4.771748e-03  4.973416e-03 ......
## ASV1183      1.371287e-03  1.432976e-03  1.497260e-03  1.564232e-03 ......
## ASV11956     1.094712e-03  1.135324e-03  1.177017e-03  1.219792e-03 ......
## ASV12774    -5.601987e-05 -6.130983e-05 -6.703250e-05 -7.321852e-05 ......
## ASV1321      5.943971e-03  6.216288e-03  6.500596e-03  6.797376e-03 ......
## ASV13793    -2.620927e-03 -2.734089e-03 -2.851571e-03 -2.973489e-03 ......
## ASV14482    -8.648194e-06 -1.184599e-05 -1.536274e-05 -1.921929e-05 ......
## ASV15483     9.939050e-04  1.039197e-03  1.086486e-03  1.135853e-03 ......
## ASV2062      4.863347e-03  5.075481e-03  5.296040e-03  5.525291e-03 ......
## ASV2132      4.327650e-03  4.525036e-03  4.731061e-03  4.946074e-03 ......
## ASV2413      3.779578e-03  3.940014e-03  4.106461e-03  4.279084e-03 ......
## ASV2490      1.151248e-02  1.198246e-02  1.246835e-02  1.297043e-02 ......
## ASV2594      1.385235e-03  1.446282e-03  1.509870e-03  1.576098e-03 ......
## ASV2822     -6.928812e-03 -7.228127e-03 -7.538886e-03 -7.861394e-03 ......
## ASV2863      7.380098e-03  7.689332e-03  8.009737e-03  8.341574e-03 ......
## ASV2910      2.561210e-03  2.668869e-03  2.780466e-03  2.896095e-03 ......
## ASV2980      2.531556e-03  2.641939e-03  2.756645e-03  2.875801e-03 ......
## ASV3307      5.486605e-03  5.723513e-03  5.969469e-03  6.224715e-03 ......
## ASV3474      3.438107e-03  3.597043e-03  3.763104e-03  3.936590e-03 ......
## ASV3502      4.062668e-03  4.242665e-03  4.430072e-03  4.625151e-03 ......
## ASV4236      5.743865e-03  5.983956e-03  6.232669e-03  6.490196e-03 ......
## ASV4842     -1.209245e-03 -1.266566e-03 -1.326426e-03 -1.388911e-03 ......
## ASV4894     -2.621738e-03 -2.734981e-03 -2.852553e-03 -2.974569e-03 ......
## ASV5290      2.108106e-03  2.201954e-03  2.299722e-03  2.401551e-03 ......
## ASV5501      1.050791e-03  1.097664e-03  1.146549e-03  1.197529e-03 ......
## ASV5795      1.291881e-03  1.349687e-03  1.409935e-03  1.472717e-03 ......
## ASV5987     -7.336136e-03 -7.653076e-03 -7.982139e-03 -8.323650e-03 ......
## ASV6267     -8.267809e-03 -8.624915e-03 -8.995672e-03 -9.380446e-03 ......
## ASV6862      3.284431e-03  3.418192e-03  3.556495e-03  3.699426e-03 ......
## ASV7145      1.182642e-03  1.226710e-03  1.271985e-03  1.318473e-03 ......
## ASV7673     -2.621371e-03 -2.734582e-03 -2.852120e-03 -2.974101e-03 ......
## ASV7789      1.173523e-03  1.231021e-03  1.291395e-03  1.354793e-03 ......
## ASV7809     -3.065550e-05 -2.996810e-05 -2.904841e-05 -2.786922e-05 ......
## ASV8002     -3.311333e-03 -3.454337e-03 -3.602807e-03 -3.756888e-03 ......
## ASV8205      1.113942e-03  1.162488e-03  1.213009e-03  1.265579e-03 ......
## ASV9155     -9.024451e-04 -9.405720e-04 -9.800632e-04 -1.020945e-03 ......
## ASV9221      7.484986e-05  7.763858e-05  8.050917e-05  8.346169e-05 ......
## ASV9311     -5.315009e-03 -5.544494e-03 -5.782746e-03 -6.030000e-03 ......
## ASV9557     -3.629550e-03 -3.786225e-03 -3.948882e-03 -4.117681e-03 ......
## ASV9936     -7.328238e-03 -7.644497e-03 -7.972825e-03 -8.313543e-03 ......
## ASV1445      4.871450e-03  5.088995e-03  5.315641e-03  5.551716e-03 ......
## ASV4232      2.202643e-03  2.305273e-03  2.412613e-03  2.524873e-03 ......
## ASV6479      4.210661e-04  4.483961e-04  4.776642e-04  5.090128e-04 ......
## ASV0142     -2.985868e-03 -3.111026e-03 -3.240727e-03 -3.375081e-03 ......
## ASV0378     -7.633838e-05 -7.470017e-05 -7.253419e-05 -6.977959e-05 ......
## ASV1122      4.809638e-03  5.025823e-03  5.251174e-03  5.486032e-03 ......
## ASV0123     -2.639031e-03 -2.749368e-03 -2.863686e-03 -2.982078e-03 ......
## ASV2064      1.474588e-03  1.533456e-03  1.594291e-03  1.657134e-03 ......
## ASV4459     -7.044006e-04 -7.367161e-04 -7.704309e-04 -8.055988e-04 ......
## ASV0448      1.076864e-03  1.128470e-03  1.182524e-03  1.239136e-03 ......
## ASV0397      2.223972e-03  2.322890e-03  2.425895e-03  2.533131e-03 ......
## ASV0485      2.874696e-03  2.999060e-03  3.128279e-03  3.262499e-03 ......
## ASV1566      4.602636e-03  4.805282e-03  5.016137e-03  5.235476e-03 ......
## ASV1365      2.917882e-03  3.043922e-03  3.174853e-03  3.310817e-03 ......
## ASV1065      5.551880e-03  5.798510e-03  6.055325e-03  6.322680e-03 ......
## ASV0722     -3.258484e-04 -3.410309e-04 -3.569338e-04 -3.735937e-04 ......
## ASV12660    -2.969844e-03 -3.094770e-03 -3.224225e-03 -3.358315e-03 ......
## ASV0223      4.648134e-04  4.852693e-04  5.065477e-04  5.286755e-04 ......
## ASV0229      1.174843e-03  1.228561e-03  1.284624e-03  1.343126e-03 ......
## ASV0877      7.502832e-05  7.573422e-05  7.629642e-05  7.669974e-05 ......
## ASV0983      2.891444e-03  3.014435e-03  3.142011e-03  3.274287e-03 ......
## ASV0626     -1.462222e-04 -1.460798e-04 -1.453661e-04 -1.440159e-04 ......
## ASV4146     -1.795106e-04 -1.889168e-04 -1.988427e-04 -2.093205e-04 ......
## ASV4175     -3.566469e-03 -3.725655e-03 -3.891442e-03 -4.064058e-03 ......
## ASV2082     -1.776253e-03 -1.865349e-03 -1.959095e-03 -2.057742e-03 ......
## ASV2272      1.601563e-03  1.671604e-03  1.744468e-03  1.820252e-03 ......
## ASV2245     -2.601615e-03 -2.718033e-03 -2.839298e-03 -2.965580e-03 ......
## ASV0590     -2.291763e-03 -2.406765e-03 -2.527730e-03 -2.654974e-03 ......
## ASV0217     -1.668246e-04 -1.650531e-04 -1.624313e-04 -1.588663e-04 ......
## ASV0416      1.906230e-03  1.980907e-03  2.057793e-03  2.136891e-03 ......
## ASV1056      2.347294e-03  2.455897e-03  2.569366e-03  2.687903e-03 ......
## ASV7777     -3.507526e-03 -3.667471e-03 -3.834395e-03 -4.008576e-03 ......
## ASV0455      4.358788e-04  4.548188e-04  4.744842e-04  4.948936e-04 ......
## ASV0604      1.453393e-03  1.522913e-03  1.595727e-03  1.671983e-03 ......
## ASV6100     -2.490809e-03 -2.604612e-03 -2.723392e-03 -2.847348e-03 ......
## ASV11359    -5.455810e-03 -5.694481e-03 -5.942595e-03 -6.200440e-03 ......
## ASV6604      1.010228e-03  1.057353e-03  1.106635e-03  1.158166e-03 ......
## ASV5004     -1.576947e-03 -1.648053e-03 -1.722180e-03 -1.799441e-03 ......
## ASV1483     -1.002749e-03 -1.048802e-03 -1.096875e-03 -1.147049e-03 ......
## ASV9773     -2.471373e-03 -2.582994e-03 -2.699378e-03 -2.820705e-03 ......
## ASV4059      1.905681e-03  1.999124e-03  2.097228e-03  2.200228e-03 ......
## ASV1193      2.968379e-03  3.099151e-03  3.235240e-03  3.376826e-03 ......
## ASV4610     -3.333294e-04 -3.412692e-04 -3.489563e-04 -3.563368e-04 ......
## ASV0742     -5.921872e-04 -6.115492e-04 -6.311263e-04 -6.508804e-04 ......
## ASV1502      2.553319e-05  2.224082e-05  1.844698e-05  1.410522e-05 ......
## ASV0195     -1.316379e-04 -1.397949e-04 -1.484879e-04 -1.577518e-04 ......
## ASV1213      2.467325e-03  2.569168e-03  2.674536e-03  2.783496e-03 ......
## ASV1648     -2.329668e-03 -2.435845e-03 -2.546647e-03 -2.662257e-03 ......
## ASV6984     -2.167407e-03 -2.265963e-03 -2.368786e-03 -2.476044e-03 ......
## ASV0396     -1.593216e-04 -1.595422e-04 -1.592303e-04 -1.583280e-04 ......
## ASV4297      3.474050e-03  3.618951e-03  3.769071e-03  3.924533e-03 ......
## ASV2622      4.607372e-03  4.802942e-03  5.005824e-03  5.216211e-03 ......
## ASV3512      1.685707e-03  1.766661e-03  1.851517e-03  1.940463e-03 ......
## ASV2411      2.924451e-03  3.058400e-03  3.198207e-03  3.344101e-03 ......
## ASV2291     -1.638956e-03 -1.723492e-03 -1.812596e-03 -1.906525e-03 ......
## ASV0807      3.388652e-03  3.544820e-03  3.707864e-03  3.878055e-03 ......
## ASV1292      1.070351e-03  1.114645e-03  1.160484e-03  1.207898e-03 ......
## ASV1035      3.081676e-03  3.210401e-03  3.343739e-03  3.481794e-03 ......
## ASV0070     -8.196608e-05 -8.280569e-05 -8.343615e-05 -8.382930e-05 ......
## ASV0255      2.766196e-04  2.865285e-04  2.966112e-04  3.068502e-04 ......
## ASV0057     -1.123724e-03 -1.169150e-03 -1.216068e-03 -1.264499e-03 ......
## ASV0077     -1.766859e-04 -1.823337e-04 -1.880288e-04 -1.937575e-04 ......
## ASV0625      2.220523e-03  2.312483e-03  2.407653e-03  2.506094e-03 ......
## ASV2464      1.485856e-02  1.547564e-02  1.611448e-02  1.677554e-02 ......
## ASV1315      4.567142e-03  4.772905e-03  4.987521e-03  5.211338e-03 ......
## ASV2673      3.988514e-03  4.175138e-03  4.370329e-03  4.574462e-03 ......
## ASV2161      1.708564e-03  1.788118e-03  1.871305e-03  1.958284e-03 ......
## ASV0337     -9.018262e-04 -9.424606e-04 -9.848317e-04 -1.029006e-03 ......
## ASV7680     -5.651672e-03 -5.908974e-03 -6.177439e-03 -6.457501e-03 ......
## ASV0611      2.963257e-03  3.098509e-03  3.239678e-03  3.387001e-03 ......
## ASV3118     -3.556081e-03 -3.721759e-03 -3.894933e-03 -4.075920e-03 ......
## ASV1284      2.237735e-03  2.336144e-03  2.438235e-03  2.544071e-03 ......
## ASV0889      2.083444e-03  2.172592e-03  2.265165e-03  2.361265e-03 ......
## ASV4649     -1.189524e-03 -1.242760e-03 -1.298225e-03 -1.356001e-03 ......
## ASV1108     -2.773859e-03 -2.905721e-03 -3.043788e-03 -3.188344e-03 ......
## ASV0738      7.403141e-04  7.856270e-04  8.338981e-04  8.853241e-04 ......
## ASV0473     -2.846289e-04 -3.003915e-04 -3.170813e-04 -3.347539e-04 ......
## ASV0598     -1.536618e-03 -1.600604e-03 -1.666898e-03 -1.735558e-03 ......
## ASV0429      2.227150e-03  2.322298e-03  2.421024e-03  2.523419e-03 ......
## ASV1549      3.039185e-03  3.182255e-03  3.331955e-03  3.488580e-03 ......
## ASV1203      2.441132e-03  2.545699e-03  2.654240e-03  2.766864e-03 ......
## ASV4532      8.659872e-06  6.765403e-06  4.616174e-06  2.190909e-06 ......
## ASV0274     -3.355949e-04 -3.463347e-04 -3.572035e-04 -3.681846e-04 ......
## ASV0163     -2.012890e-03 -2.096162e-03 -2.182365e-03 -2.271562e-03 ......
## ASV1298      8.169883e-04  8.500883e-04  8.843162e-04  9.196975e-04 ......
## ASV9424     -4.892129e-03 -5.116645e-03 -5.351084e-03 -5.595854e-03 ......
## ASV0412      4.088472e-03  4.264363e-03  4.447014e-03  4.636618e-03 ......
## ASV0284      9.708275e-04  1.008028e-03  1.046247e-03  1.085479e-03 ......
## ASV0620     -1.190341e-03 -1.250514e-03 -1.313802e-03 -1.380366e-03 ......
## ASV0153     -3.421900e-03 -3.581979e-03 -3.749391e-03 -3.924459e-03 ......
## ASV0498      1.322753e-03  1.385209e-03  1.450500e-03  1.518737e-03 ......
## ASV0097      8.831497e-04  9.243328e-04  9.674022e-04  1.012442e-03 ......
## ASV0104     -5.702723e-03 -5.953315e-03 -6.214064e-03 -6.485312e-03 ......
## ASV1282      1.509823e-03  1.576178e-03  1.645110e-03  1.716684e-03 ......
## ASV3883     -1.766111e-03 -1.850009e-03 -1.937817e-03 -2.029706e-03 ......
## ASV0801      1.130594e-03  1.184469e-03  1.240871e-03  1.299915e-03 ......
## ASV1611     -3.998086e-03 -4.181817e-03 -4.373678e-03 -4.574000e-03 ......
## ASV0227     -8.836386e-04 -9.274082e-04 -9.733746e-04 -1.021647e-03 ......
## ASV0833      1.147148e-03  1.199414e-03  1.253947e-03  1.310832e-03 ......
## ASV0718      5.572196e-03  5.822415e-03  6.083213e-03  6.354983e-03 ......
## ASV1139      6.856131e-04  7.087768e-04  7.322474e-04  7.559791e-04 ......
## ASV0766     -9.902599e-04 -1.037546e-03 -1.087076e-03 -1.138954e-03 ......
## ASV2091      5.573663e-03  5.803787e-03  6.041995e-03  6.288461e-03 ......
## ASV1238     -1.905715e-03 -1.979518e-03 -2.055779e-03 -2.134575e-03 ......
## ASV9193     -9.159228e-04 -9.713902e-04 -1.030162e-03 -1.092410e-03 ......
## ASV0290      7.687169e-05  7.745334e-05  7.783531e-05  7.799486e-05 ......
## ASV0231      1.791528e-03  1.868854e-03  1.949171e-03  2.032564e-03 ......
## ASV0185      7.693429e-04  8.114474e-04  8.559712e-04  9.030556e-04 ......
## ASV2330      1.613250e-03  1.678086e-03  1.745001e-03  1.814014e-03 ......
## ASV3119     -1.012720e-03 -1.064833e-03 -1.119724e-03 -1.177544e-03 ......
## ASV2368     -2.524161e-03 -2.643334e-03 -2.768076e-03 -2.898640e-03 ......
## ASV0122     -7.904969e-04 -8.237788e-04 -8.582910e-04 -8.940662e-04 ......
## ASV1044      2.718098e-03  2.847079e-03  2.982125e-03  3.123515e-03 ......
## ASV0160     -1.299841e-03 -1.351832e-03 -1.405502e-03 -1.460875e-03 ......
## ASV0326      3.888280e-04  4.060350e-04  4.239440e-04  4.425783e-04 ......
## ASV1388      6.766888e-03  7.062668e-03  7.370251e-03  7.690015e-03 ......
## ASV0792      4.057571e-03  4.230345e-03  4.409593e-03  4.595484e-03 ......
## ASV0036     -1.104894e-03 -1.156217e-03 -1.209857e-03 -1.265911e-03 ......
## ASV2125      3.738761e-03  3.901188e-03  4.069999e-03  4.245387e-03 ......
## ASV1075      1.861515e-04  1.951367e-04  2.045624e-04  2.144504e-04 ......
## ASV0390      2.110712e-03  2.212443e-03  2.319099e-03  2.430919e-03 ......
## ASV3790     -3.109435e-03 -3.249154e-03 -3.394814e-03 -3.546641e-03 ......
## ASV1535     -6.395686e-04 -6.749481e-04 -7.123554e-04 -7.519060e-04 ......
## ASV0263      2.797998e-03  2.921165e-03  3.049298e-03  3.182556e-03 ......
## ASV0675      5.496277e-03  5.749702e-03  6.014381e-03  6.290771e-03 ......
## ASV3348      6.006024e-04  6.302017e-04  6.612898e-04  6.939425e-04 ......
## ASV0058     -1.776780e-03 -1.852391e-03 -1.930860e-03 -2.012266e-03 ......
## ASV4142      2.136281e-03  2.227487e-03  2.322144e-03  2.420348e-03 ......
## ASV0059     -1.463072e-03 -1.524632e-03 -1.588457e-03 -1.654604e-03 ......
## ASV0013     -2.060627e-03 -2.151851e-03 -2.246830e-03 -2.345698e-03 ......
## ASV0033     -1.053363e-03 -1.102435e-03 -1.153735e-03 -1.207359e-03 ......
## ASV4354     -1.387522e-03 -1.449888e-03 -1.514915e-03 -1.582708e-03 ......
## ASV0022     -8.339255e-04 -8.729446e-04 -9.137515e-04 -9.564241e-04 ......
## ASV0134     -9.148424e-04 -9.587681e-04 -1.004808e-03 -1.053062e-03 ......
## ASV0415      1.356976e-04  1.463584e-04  1.578164e-04  1.701243e-04 ......
## ASV10103    -4.955937e-03 -5.183058e-03 -5.420163e-03 -5.667651e-03 ......
## ASV1613      3.677292e-03  3.832759e-03  3.993946e-03  4.160990e-03 ......
## ASV0135     -5.787975e-04 -6.011279e-04 -6.240726e-04 -6.476251e-04 ......
## ASV0469     -4.666832e-03 -4.866303e-03 -5.073377e-03 -5.288273e-03 ......
## ASV0471      3.510496e-03  3.669622e-03  3.835522e-03  4.008445e-03 ......
## ASV0451     -5.702196e-04 -6.011639e-04 -6.338941e-04 -6.685181e-04 ......
## ASV0747      1.248752e-03  1.307079e-03  1.368040e-03  1.431743e-03 ......
## ASV1314     -1.578059e-03 -1.653563e-03 -1.732680e-03 -1.815579e-03 ......
## ASV0425     -6.587231e-03 -6.858937e-03 -7.140194e-03 -7.431210e-03 ......
## ASV0559     -1.897467e-03 -1.978972e-03 -2.063671e-03 -2.151671e-03 ......
## ASV0148     -1.023709e-03 -1.063490e-03 -1.104434e-03 -1.146541e-03 ......
## ASV0129     -2.467560e-04 -2.495123e-04 -2.517030e-04 -2.532541e-04 ......
## ASV1072      7.151879e-04  7.426276e-04  7.708635e-04  7.998989e-04 ......
## ASV2390      2.478821e-03  2.578687e-03  2.681759e-03  2.788067e-03 ......
## ASV0548      2.272170e-03  2.372963e-03  2.477930e-03  2.587221e-03 ......
## ASV0168     -1.502554e-03 -1.566650e-03 -1.633183e-03 -1.702225e-03 ......
## ASV0066     -1.252130e-03 -1.307189e-03 -1.364469e-03 -1.424044e-03 ......
## ASV0468     -8.168114e-04 -8.534670e-04 -8.916736e-04 -9.314893e-04 ......
## ASV0172     -3.445975e-04 -3.562272e-04 -3.680345e-04 -3.800017e-04 ......
## ASV0236     -5.916623e-04 -6.065595e-04 -6.211505e-04 -6.353544e-04 ......
## ASV0250      9.571687e-04  1.011224e-03  1.068477e-03  1.129117e-03 ......
## ASV0338      8.532888e-04  8.965578e-04  9.420286e-04  9.898071e-04 ......
## ASV0450     -8.482392e-05 -9.021099e-05 -9.596733e-05 -1.021190e-04 ......
## ASV0377      1.732777e-03  1.809037e-03  1.888382e-03  1.970913e-03 ......
## ASV1022      2.281336e-04  2.385689e-04  2.494680e-04  2.608506e-04 ......
## ASV6174     -2.198535e-04 -2.310371e-04 -2.428159e-04 -2.552239e-04 ......
## ASV0786      1.226991e-04  1.247846e-04  1.266543e-04  1.282741e-04 ......
## ASV0053     -1.618078e-03 -1.690993e-03 -1.767006e-03 -1.846234e-03 ......
## ASV0697     -1.256506e-03 -1.309759e-03 -1.365024e-03 -1.422361e-03 ......
## ASV0785      2.361157e-03  2.463690e-03  2.570310e-03  2.681152e-03 ......
## ASV1967     -2.152611e-03 -2.244397e-03 -2.339651e-03 -2.438469e-03 ......
## ASV0385      3.445233e-04  3.633649e-04  3.832291e-04  4.041647e-04 ......
## ASV0295      1.224308e-04  1.310718e-04  1.403551e-04  1.503284e-04 ......
## ASV0072     -1.500762e-03 -1.563346e-03 -1.628178e-03 -1.695310e-03 ......
## ASV0157     -5.190137e-04 -5.374013e-04 -5.561194e-04 -5.751400e-04 ......
## ASV0501      4.062595e-03  4.251127e-03  4.447937e-03  4.653332e-03 ......
## ASV10729    -4.742434e-03 -4.958955e-03 -5.184935e-03 -5.420753e-03 ......
## ASV1470      2.498325e-03  2.588093e-03  2.679904e-03  2.773704e-03 ......
## ASV0050     -3.585842e-03 -3.741802e-03 -3.903948e-03 -4.072480e-03 ......
## ASV0411     -6.553372e-04 -6.844561e-04 -7.148144e-04 -7.464626e-04 ......
## ASV0549      1.182178e-03  1.236888e-03  1.294076e-03  1.353850e-03 ......
## ASV0184      3.575277e-04  3.731506e-04  3.894010e-04  4.063000e-04 ......
## ASV0705      9.407690e-04  9.829911e-04  1.026981e-03  1.072801e-03 ......
## ASV1715      2.115099e-03  2.209363e-03  2.307552e-03  2.409806e-03 ......
## ASV0603      3.446139e-04  3.610131e-04  3.781977e-04  3.962063e-04 ......
## ASV0826      2.821627e-03  2.942728e-03  3.068488e-03  3.199044e-03 ......
## ASV0034     -1.131735e-03 -1.179638e-03 -1.229311e-03 -1.280796e-03 ......
## ASV0838      1.544481e-03  1.607543e-03  1.672674e-03  1.739896e-03 ......
## ASV0614     -1.320089e-03 -1.378349e-03 -1.438985e-03 -1.502081e-03 ......
## ASV0014     -2.064756e-03 -2.155487e-03 -2.249897e-03 -2.348110e-03 ......
## ASV0585     -1.883512e-04 -1.979356e-04 -2.080477e-04 -2.187193e-04 ......
## ASV0016     -2.166392e-03 -2.261647e-03 -2.360770e-03 -2.463891e-03 ......
## ASV5394     -2.130527e-03 -2.226198e-03 -2.325903e-03 -2.429788e-03 ......
## ASV0666      3.868933e-03  4.031884e-03  4.200794e-03  4.375805e-03 ......
## ASV2085      7.360320e-04  7.541813e-04  7.718339e-04  7.888693e-04 ......
## ASV0003     -1.501692e-03 -1.567579e-03 -1.636132e-03 -1.707439e-03 ......
## ASV0346      4.213608e-04  4.441905e-04  4.683060e-04  4.937794e-04 ......
## ASV0267     -1.575583e-04 -1.606010e-04 -1.633944e-04 -1.658950e-04 ......
## ASV0353      1.295605e-03  1.358930e-03  1.425330e-03  1.494947e-03 ......
## ASV2419      4.067680e-03  4.242470e-03  4.423976e-03  4.612394e-03 ......
## ASV0447      1.771510e-03  1.854503e-03  1.941277e-03  2.031990e-03 ......
## ASV0654      2.839135e-03  2.965936e-03  3.098027e-03  3.235597e-03 ......
## ASV0151      2.670892e-04  2.819963e-04  2.977951e-04  3.145417e-04 ......
## ASV0065     -1.119801e-03 -1.167012e-03 -1.215969e-03 -1.266716e-03 ......
## ASV0527      3.047598e-03  3.181946e-03  3.321762e-03  3.467231e-03 ......
## ASV4055     -7.523123e-04 -7.897338e-04 -8.290760e-04 -8.704422e-04 ......
## ASV0166     -1.460401e-03 -1.516806e-03 -1.574889e-03 -1.634662e-03 ......
## ASV0417     -1.120842e-03 -1.166439e-03 -1.213550e-03 -1.262194e-03 ......
## ASV0078     -7.965856e-04 -8.290316e-04 -8.625748e-04 -8.972343e-04 ......
## ASV0322     -8.810044e-04 -9.110286e-04 -9.416181e-04 -9.727481e-04 ......
## ASV0156     -1.879328e-03 -1.959608e-03 -2.043008e-03 -2.129630e-03 ......
## ASV0648     -5.975363e-03 -6.248850e-03 -6.534355e-03 -6.832363e-03 ......
## ASV0407     -1.792545e-04 -1.879610e-04 -1.970725e-04 -2.066052e-04 ......
## ASV2030     -7.837576e-04 -8.179293e-04 -8.535065e-04 -8.905452e-04 ......
## ASV0300      5.334997e-04  5.599170e-04  5.876399e-04  6.167299e-04 ......
## ASV1150     -3.572018e-05 -3.644184e-05 -3.711928e-05 -3.774505e-05 ......
## ASV0958      1.540568e-03  1.613982e-03  1.690879e-03  1.771422e-03 ......
## ASV0216     -1.671427e-03 -1.743169e-03 -1.817689e-03 -1.895073e-03 ......
## ASV0446      2.587020e-03  2.707337e-03  2.833068e-03  2.964436e-03 ......
## ASV0367     -1.913165e-03 -1.999765e-03 -2.090097e-03 -2.184307e-03 ......
## ASV0200     -1.055282e-03 -1.101578e-03 -1.149754e-03 -1.199874e-03 ......
## ASV0334     -5.861765e-04 -6.065488e-04 -6.272933e-04 -6.483867e-04 ......
## ASV1311      6.809517e-04  7.091266e-04  7.382854e-04  7.684476e-04 ......
## ASV0458      1.453167e-03  1.511816e-03  1.572361e-03  1.634825e-03 ......
## ASV1371      1.666063e-04  1.745042e-04  1.827613e-04  1.913913e-04 ......
## ASV0418      3.511027e-03  3.652063e-03  3.797717e-03  3.948058e-03 ......
## ASV0004      3.463308e-04  3.607224e-04  3.756246e-04  3.910482e-04 ......
## ASV1943      1.215125e-02  1.264993e-02  1.316595e-02  1.369968e-02 ......
## ASV1495     -6.494117e-04 -6.870671e-04 -7.270449e-04 -7.694917e-04 ......
## ASV0901     -2.395244e-03 -2.505540e-03 -2.620754e-03 -2.741093e-03 ......
## ASV0628      1.048002e-03  1.090493e-03  1.134369e-03  1.179644e-03 ......
## ASV0400      5.682980e-04  5.930885e-04  6.188481e-04  6.456042e-04 ......
## ASV0116     -6.692961e-04 -6.997363e-04 -7.315045e-04 -7.646542e-04 ......
## ASV0788      4.751815e-03  4.967607e-03  5.192734e-03  5.427560e-03 ......
## ASV0117      4.310360e-04  4.518828e-04  4.737428e-04  4.966645e-04 ......
## ASV3137     -8.896006e-06 -8.802401e-06 -8.656029e-06 -8.450163e-06 ......
## ASV0001      4.140488e-04  4.309851e-04  4.485041e-04  4.666174e-04 ......
## ASV1651      1.056256e-03  1.098696e-03  1.142523e-03  1.187759e-03 ......
## ASV1692      3.986059e-03  4.168818e-03  4.359626e-03  4.558810e-03 ......
## ASV0660      1.215019e-03  1.261266e-03  1.308703e-03  1.357305e-03 ......
## ASV0508     -3.714019e-05 -3.997812e-05 -4.303118e-05 -4.631456e-05 ......
## ASV1660     -1.184773e-03 -1.241897e-03 -1.301759e-03 -1.364483e-03 ......
## ASV0233      8.332151e-04  8.701104e-04  9.085318e-04  9.485344e-04 ......
## ASV1343     -2.689366e-03 -2.812734e-03 -2.941561e-03 -3.076072e-03 ......
## ASV0209      1.177738e-03  1.226601e-03  1.277187e-03  1.329534e-03 ......
## ASV0193     -1.517139e-03 -1.574239e-03 -1.632921e-03 -1.693187e-03 ......
## ASV0357      3.328182e-04  3.499632e-04  3.680295e-04  3.870683e-04 ......
## ASV0198      9.860059e-04  1.030544e-03  1.076966e-03  1.125341e-03 ......
## ASV0007      4.313965e-04  4.488625e-04  4.669144e-04  4.855624e-04 ......
## ASV1772     -6.321059e-04 -6.577047e-04 -6.841108e-04 -7.113259e-04 ......
## ASV0009      4.014521e-04  4.175478e-04  4.341697e-04  4.513258e-04 ......
## ASV0006     -6.387435e-05 -6.778405e-05 -7.193953e-05 -7.635554e-05 ......
## ASV0011     -8.436200e-04 -8.819620e-04 -9.219611e-04 -9.636814e-04 ......
## ASV0015      2.619428e-04  2.724378e-04  2.832672e-04  2.944341e-04 ......
## ASV0017      2.845332e-04  2.959450e-04  3.077235e-04  3.198727e-04 ......
## ASV0235     -1.070135e-03 -1.120468e-03 -1.173105e-03 -1.228143e-03 ......
## ASV0382      4.640196e-04  4.872986e-04  5.117262e-04  5.373528e-04 ......
## ASV2357      3.382545e-03  3.536338e-03  3.696814e-03  3.864237e-03 ......
## ASV0567     -8.801473e-04 -9.189085e-04 -9.592689e-04 -1.001287e-03 ......
## ASV0165      5.974757e-04  6.250118e-04  6.537684e-04  6.837949e-04 ......
## ASV0005      7.010602e-04  7.312249e-04  7.625559e-04  7.950878e-04 ......
## ASV0384     -1.311170e-05 -1.093027e-05 -8.406467e-06 -5.505363e-06 ......
## ASV0002      1.210158e-04  1.263025e-04  1.318011e-04  1.375185e-04 ......
## ASV3017      4.482445e-03  4.672529e-03  4.869731e-03  5.074243e-03 ......
## ASV0091      3.662812e-07  5.154766e-07  6.781282e-07  8.546926e-07 ......
## ASV0186     -1.867291e-03 -1.950459e-03 -2.037069e-03 -2.127240e-03 ......
## ASV0370      5.626875e-04  5.889703e-04  6.164594e-04  6.452084e-04 ......
## ASV0018      9.589181e-04  1.000380e-03  1.043465e-03  1.088222e-03 ......
## ASV1377      1.448718e-02  1.510733e-02  1.575106e-02  1.641905e-02 ......
## ASV0019      1.004991e-03  1.048505e-03  1.093727e-03  1.140709e-03 ......
## ASV0023     -3.173105e-04 -3.326556e-04 -3.487323e-04 -3.655732e-04 ......
## ASV2194      1.134848e-03  1.184755e-03  1.236735e-03  1.290864e-03 ......
## ASV1155      2.211893e-03  2.310967e-03  2.414181e-03  2.521683e-03 ......
## ASV0510     -1.508580e-03 -1.562072e-03 -1.616792e-03 -1.672722e-03 ......
## ASV2371     -2.382931e-03 -2.480400e-03 -2.581186e-03 -2.685348e-03 ......
## ASV0024     -4.243376e-04 -4.444918e-04 -4.655808e-04 -4.876449e-04 ......
## ASV2452      2.745131e-03  2.857185e-03  2.973058e-03  3.092822e-03 ......
## ASV2332     -3.254156e-03 -3.392832e-03 -3.536511e-03 -3.685288e-03 ......
## ASV2591      2.396036e-03  2.517666e-03  2.645584e-03  2.780109e-03 ......
## ASV0521      1.591541e-03  1.664676e-03  1.741035e-03  1.820746e-03 ......
## ASV5542      1.391450e-03  1.455291e-03  1.521914e-03  1.591423e-03 ......
## ASV0336     -4.678882e-04 -4.861226e-04 -5.049702e-04 -5.244497e-04 ......
## ASV10102     2.931243e-03  3.066856e-03  3.208541e-03  3.356547e-03 ......
## ASV16823    -3.967110e-03 -4.128703e-03 -4.295757e-03 -4.468367e-03 ......
## ASV3104      2.188829e-02  2.277968e-02  2.370117e-02  2.465330e-02 ......
## ASV0781      2.646031e-03  2.765383e-03  2.889831e-03  3.019569e-03 ......
## ASV10899     1.776143e-03  1.866731e-03  1.962061e-03  2.062381e-03 ......
## ASV11222    -6.927194e-03 -7.209281e-03 -7.500894e-03 -7.802203e-03 ......
## ASV11327    -6.229305e-03 -6.482918e-03 -6.745092e-03 -7.015978e-03 ......
## ASV12458    -6.924235e-03 -7.206080e-03 -7.497434e-03 -7.798464e-03 ......
## ASV1636      6.024909e-04  6.313257e-04  6.615168e-04  6.931235e-04 ......
## ASV1890     -4.447925e-03 -4.625620e-03 -4.809013e-03 -4.998175e-03 ......
## ASV2898      5.439983e-03  5.673487e-03  5.915929e-03  6.167563e-03 ......
## ASV8328      4.373241e-04  4.768654e-04  5.197658e-04  5.662852e-04 ......
## ASV0709     -6.073678e-03 -6.337771e-03 -6.612278e-03 -6.897522e-03 ......
## ASV0856      4.402116e-03  4.608648e-03  4.824658e-03  5.050556e-03 ......
## ASV0909     -1.212376e-04 -1.079209e-04 -9.248450e-05 -7.472933e-05 ......
## ASV0937     -3.590009e-03 -3.751525e-03 -3.919928e-03 -4.095484e-03 ......
## ASV11390    -9.805891e-03 -1.020494e-02 -1.061745e-02 -1.104366e-02 ......
## ASV11966     2.549837e-03  2.673170e-03  2.802447e-03  2.937942e-03 ......
## ASV12990     1.636073e-03  1.709159e-03  1.785278e-03  1.864534e-03 ......
## ASV14797     2.714354e-03  2.829534e-03  2.949010e-03  3.072894e-03 ......
## ASV14904    -1.391927e-02 -1.448571e-02 -1.507126e-02 -1.567625e-02 ......
## ASV15304     1.409314e-03  1.482265e-03  1.559098e-03  1.640017e-03 ......
## ASV16696    -4.923013e-03 -5.123329e-03 -5.330400e-03 -5.544344e-03 ......
## ASV1690      8.912867e-03  9.328139e-03  9.762055e-03  1.021537e-02 ......
## ASV2029      6.163795e-03  6.429999e-03  6.706543e-03  6.993734e-03 ......
## ASV2834      1.010887e-02  1.056195e-02  1.103406e-02  1.152589e-02 ......
## ASV4003      6.323169e-03  6.629515e-03  6.950775e-03  7.287667e-03 ......
## ASV4064      3.771454e-03  3.937843e-03  4.110999e-03  4.291148e-03 ......
## ASV4294      2.311400e-03  2.430361e-03  2.555685e-03  2.687720e-03 ......
## ASV4609      1.122804e-03  1.169521e-03  1.217975e-03  1.268218e-03 ......
## ASV6283     -4.606393e-03 -4.793874e-03 -4.987684e-03 -5.187933e-03 ......
## ASV6491     -6.567549e-03 -6.834792e-03 -7.111051e-03 -7.396486e-03 ......
## ASV7453      3.241957e-03  3.399319e-03  3.564267e-03  3.737147e-03 ......
## ASV7959      9.369416e-04  9.907492e-04  1.047804e-03  1.108302e-03 ......
## ASV8219      6.768703e-02  7.044117e-02  7.328823e-02  7.622985e-02 ......
## ASV8547     -5.888434e-03 -6.127979e-03 -6.375601e-03 -6.631444e-03 ......
## ASV9319      2.719047e-03  2.845436e-03  2.977530e-03  3.115570e-03 ......
## ASV9382     -1.135696e-02 -1.181892e-02 -1.229647e-02 -1.278986e-02 ......
## ASV11516    -7.657629e-03 -7.969051e-03 -8.290968e-03 -8.623566e-03 ......
## ASV14377    -5.558243e-03 -5.784238e-03 -6.017846e-03 -6.259200e-03 ......
## ASV1867      4.941345e-03  5.166612e-03  5.401707e-03  5.647021e-03 ......
## ASV1895      8.205919e-04  8.554610e-04  8.915473e-04  9.288637e-04 ......
## ASV3168      2.615320e-03  2.725424e-03  2.839532e-03  2.957735e-03 ......
## ASV4449      1.709800e-02  1.784783e-02  1.862794e-02  1.943935e-02 ......
## ASV6596      3.475415e-03  3.647507e-03  3.828298e-03  4.018237e-03 ......
## ASV7492     -6.223777e-04 -6.360502e-04 -6.491279e-04 -6.614998e-04 ......
## ASV9854     -1.420582e-03 -1.475959e-03 -1.532996e-03 -1.591705e-03 ......
## ASV6296      1.247164e-01  1.297861e-01  1.350265e-01  1.404406e-01 ......
## ASV4201      1.606332e-03  1.695629e-03  1.790161e-03  1.890241e-03 ......
## ASV0552      3.215158e-03  3.361802e-03  3.514819e-03  3.674458e-03 ......
## ASV3671     -1.561900e-03 -1.626052e-03 -1.692489e-03 -1.761271e-03 ......
## ASV3529     -6.844197e-04 -7.036853e-04 -7.228538e-04 -7.418568e-04 ......
## ASV1060      1.242606e-03  1.299708e-03  1.359344e-03  1.421620e-03 ......
## ASV0239     -1.211934e-03 -1.258985e-03 -1.307381e-03 -1.357118e-03 ......
## ASV5711     -4.940399e-03 -5.151267e-03 -5.370161e-03 -5.597313e-03 ......
## ASV4152     -8.124320e-03 -8.478496e-03 -8.846741e-03 -9.229507e-03 ......
## ASV1461      3.640694e-03  3.789849e-03  3.944084e-03  4.103486e-03 ......
## ASV2877      1.879568e-03  1.956189e-03  2.035373e-03  2.117158e-03 ......
## ASV0012      2.711042e-04  2.832356e-04  2.958758e-04  3.090434e-04 ......
## ASV9823      4.954892e-04  5.074845e-04  5.192959e-04  5.308804e-04 ......
## ASV0008      2.882379e-04  3.009945e-04  3.142751e-04  3.280980e-04 ......
## ASV7832     -5.122074e-03 -5.349160e-03 -5.585624e-03 -5.831800e-03 ......
## ASV1915     -7.020343e-05 -7.004659e-05 -6.964721e-05 -6.898383e-05 ......
## ASV0055      8.050031e-06  6.426023e-06  4.554072e-06  2.409108e-06 ......
## ASV0032      5.310518e-04  5.534819e-04  5.767428e-04  6.008562e-04 ......
## ASV2977     -7.048966e-03 -7.351310e-03 -7.665203e-03 -7.990971e-03 ......
## ASV0466      5.097920e-03  5.302492e-03  5.513638e-03  5.731431e-03 ......
## ASV3866      3.696185e-03  3.864678e-03  4.040516e-03  4.223991e-03 ......
## ASV0040      9.728289e-04  1.016540e-03  1.062101e-03  1.109577e-03 ......
## ASV0496     -4.426817e-04 -4.703778e-04 -4.999170e-04 -5.314230e-04 ......
## ASV0052      1.229671e-03  1.283885e-03  1.340305e-03  1.399003e-03 ......
## ASV3828     -7.528606e-03 -7.857679e-03 -8.200003e-03 -8.556030e-03 ......
## ASV1930      2.379905e-03  2.484721e-03  2.593758e-03  2.707151e-03 ......
## ASV2126      2.909094e-03  3.035277e-03  3.166420e-03  3.302679e-03 ......
## ASV0793      3.375937e-03  3.528335e-03  3.687210e-03  3.852802e-03 ......
## ASV0299     -2.666317e-04 -2.785025e-04 -2.908812e-04 -3.037897e-04 ......
## ASV0208      2.439754e-03  2.552034e-03  2.669272e-03  2.791670e-03 ......
## ASV0511     -1.316909e-03 -1.370651e-03 -1.426231e-03 -1.483686e-03 ......
## ASV1123     -4.143467e-03 -4.308695e-03 -4.479197e-03 -4.655041e-03 ......
## ASV0099     -1.107086e-04 -1.134801e-04 -1.161834e-04 -1.188010e-04 ......
## ASV0752     -1.407613e-03 -1.476298e-03 -1.548371e-03 -1.623998e-03 ......
## ASV0883      1.735667e-03  1.816029e-03  1.899978e-03  1.987659e-03 ......
## ASV0683      3.625865e-03  3.794340e-03  3.970410e-03  4.154395e-03 ......
## ASV4117     -8.603075e-03 -8.977246e-03 -9.366248e-03 -9.770556e-03 ......
## ASV2172      6.761411e-04  7.039025e-04  7.326256e-04  7.623295e-04 ......
## ASV0330     -1.007820e-03 -1.052551e-03 -1.099149e-03 -1.147684e-03 ......
## ASV0728      5.320616e-03  5.556586e-03  5.802254e-03  6.057951e-03 ......
## ASV0499      1.324129e-03  1.385818e-03  1.450313e-03  1.517736e-03 ......
## ASV0120     -2.208695e-03 -2.305952e-03 -2.407140e-03 -2.512386e-03 ......
## ASV1446      2.005211e-03  2.079380e-03  2.155301e-03  2.232923e-03 ......
## ASV17171    -3.947718e-03 -4.122464e-03 -4.304425e-03 -4.493859e-03 ......
## ASV0533      3.858807e-04  4.046529e-04  4.243427e-04  4.449942e-04 ......
## ASV2495     -1.518328e-03 -1.593853e-03 -1.673247e-03 -1.756714e-03 ......
## ASV5582      1.583400e-03  1.638962e-03  1.695588e-03  1.753218e-03 ......
## ASV1488      1.633589e-03  1.715652e-03  1.801707e-03  1.891921e-03 ......
## ASV0682      9.990912e-04  1.046641e-03  1.096439e-03  1.148589e-03 ......
## ASV0068     -1.053630e-03 -1.100782e-03 -1.149897e-03 -1.201041e-03 ......
## ASV1987     -4.060596e-03 -4.253588e-03 -4.455665e-03 -4.667243e-03 ......
## ASV0035     -2.032833e-04 -2.164695e-04 -2.305780e-04 -2.456749e-04 ......
## ASV7192     -2.870505e-03 -2.990468e-03 -3.114734e-03 -3.243398e-03 ......
## ASV0873      5.496534e-04  5.180691e-04  4.806579e-04  4.368824e-04 ......
## ASV4749     -1.541284e-04 -1.747529e-04 -1.974444e-04 -2.223801e-04 ......
## ASV2174      2.608206e-03  2.706833e-03  2.808338e-03  2.912755e-03 ......
## ASV1476     -1.847569e-03 -1.931730e-03 -2.019585e-03 -2.111286e-03 ......
## ASV0740     -6.409024e-03 -6.703226e-03 -7.010400e-03 -7.331068e-03 ......
## ASV0170     -8.171354e-04 -8.537337e-04 -8.918694e-04 -9.315985e-04 ......
## ASV2466     -6.100849e-03 -6.372374e-03 -6.655218e-03 -6.949792e-03 ......
## ASV1709      2.462795e-03  2.565410e-03  2.671739e-03  2.781875e-03 ......
## ASV6170     -1.406216e-02 -1.466640e-02 -1.529465e-02 -1.594777e-02 ......
## ASV3673      4.157547e-03  4.332238e-03  4.513594e-03  4.701832e-03 ......
## ASV1745      5.108937e-04  5.214086e-04  5.315715e-04  5.413302e-04 ......
## ASV0380     -2.918874e-03 -3.007156e-03 -3.096158e-03 -3.185722e-03 ......
## ASV0426      2.963088e-04  3.176079e-04  3.404126e-04  3.648223e-04 ......
## ASV0202      9.023086e-05  1.000723e-04  1.108135e-04  1.225257e-04 ......
## ASV6350     -4.471390e-03 -4.651081e-03 -4.837114e-03 -5.029677e-03 ......
## ASV0713     -2.011952e-03 -2.103093e-03 -2.198170e-03 -2.297335e-03 ......
## ASV1822      2.168908e-04  2.306529e-04  2.452625e-04  2.607659e-04 ......
## ASV4569      5.878636e-03  6.125861e-03  6.382433e-03  6.648641e-03 ......
## ASV0030     -5.533614e-04 -5.787519e-04 -6.052399e-04 -6.328657e-04 ......
## ASV0331      2.216885e-03  2.320968e-03  2.429838e-03  2.543705e-03 ......
## ASV2981      6.243599e-03  6.528286e-03  6.825239e-03  7.134918e-03 ......
## ASV0828     -1.477680e-03 -1.585330e-03 -1.700764e-03 -1.824512e-03 ......
## ASV2440      5.436568e-03  5.684262e-03  5.942681e-03  6.212238e-03 ......
## ASV3006     -2.539939e-02 -2.628070e-02 -2.718283e-02 -2.810578e-02 ......
## ASV3875      2.361267e-01  2.443185e-01  2.527038e-01  2.612825e-01 ......
## ASV4511      3.091223e-03  3.234814e-03  3.384907e-03  3.541781e-03 ......
## ASV4700     -9.337370e-03 -9.661250e-03 -9.992778e-03 -1.033195e-02 ......
## ASV5804     -2.192492e-01 -2.268529e-01 -2.346361e-01 -2.425987e-01 ......
## ASV6826      4.482524e-03  4.693858e-03  4.915009e-03  5.146416e-03 ......
## ASV7280      4.226538e-03  4.428346e-03  4.639457e-03  4.860254e-03 ......
## ASV7535     -9.335143e-03 -9.658896e-03 -9.990294e-03 -1.032933e-02 ......
## ASV0651     -2.073735e-03 -2.158222e-03 -2.245499e-03 -2.335600e-03 ......
## ASV0913      5.040797e-03  5.275069e-03  5.520002e-03  5.776064e-03 ......
## ASV10832    -9.959879e-03 -1.030524e-02 -1.065876e-02 -1.102042e-02 ......
## ASV1117     -1.083689e-02 -1.129104e-02 -1.176209e-02 -1.225054e-02 ......
## ASV11329     1.959351e-03  2.065266e-03  2.177053e-03  2.295032e-03 ......
## ASV13209     5.586139e-04  6.033802e-04  6.512024e-04  7.022364e-04 ......
## ASV1345      2.740576e-03  2.868749e-03  3.002387e-03  3.141657e-03 ......
## ASV1719     -1.402424e-02 -1.451051e-02 -1.500826e-02 -1.551748e-02 ......
## ASV1886      2.940837e-03  3.067912e-03  3.200132e-03  3.337690e-03 ......
## ASV2158      1.512345e-04  1.790469e-04  2.091873e-04  2.417715e-04 ......
## ASV2189      5.028918e-03  5.250910e-03  5.482038e-03  5.722627e-03 ......
## ASV2257      5.176225e-03  5.403354e-03  5.639981e-03  5.886487e-03 ......
## ASV2283      1.086106e-02  1.123747e-02  1.162276e-02  1.201692e-02 ......
## ASV2328      6.690431e-03  6.922267e-03  7.159564e-03  7.402320e-03 ......
## ASV2434     -6.899939e-03 -7.183645e-03 -7.477870e-03 -7.782957e-03 ......
## ASV2648      1.220889e-02  1.263174e-02  1.306454e-02  1.350727e-02 ......
## ASV2698      1.393058e-02  1.456400e-02  1.522521e-02  1.591536e-02 ......
## ASV2775      4.059380e-03  4.222043e-03  4.390128e-03  4.563740e-03 ......
## ASV3171      5.883598e-03  6.087278e-03  6.295741e-03  6.508983e-03 ......
## ASV3227      6.204021e-03  6.448323e-03  6.700402e-03  6.960379e-03 ......
## ASV3397      3.241198e-03  3.390412e-03  3.545805e-03  3.707551e-03 ......
## ASV3444      8.948679e-03  9.309959e-03  9.684152e-03  1.007165e-02 ......
## ASV3556      2.446463e-02  2.531111e-02  2.617744e-02  2.706358e-02 ......
## ASV3606     -5.749607e-02 -5.948512e-02 -6.152079e-02 -6.360301e-02 ......
## ASV4190      8.855882e-03  9.251804e-03  9.664544e-03  1.009476e-02 ......
## ASV4197      5.260200e-03  5.468405e-03  5.683435e-03  5.905421e-03 ......
## ASV4722      8.313584e-03  8.670866e-03  9.042115e-03  9.427776e-03 ......
## ASV4765      4.539271e-03  4.742840e-03  4.954494e-03  5.174447e-03 ......
## ASV4809      1.445027e-02  1.494992e-02  1.546127e-02  1.598429e-02 ......
## ASV4846      7.696772e-03  8.040761e-03  8.398994e-03  8.771959e-03 ......
## ASV4903     -4.305215e-05 -2.166092e-05  2.028627e-06  2.815693e-05 ......
## ASV4944     -5.917952e-03 -6.122573e-03 -6.331983e-03 -6.546175e-03 ......
## ASV5151     -7.315298e-04 -8.893220e-04 -1.062334e-03 -1.251627e-03 ......
## ASV5413     -1.301759e-02 -1.346768e-02 -1.392831e-02 -1.439947e-02 ......
## ASV5537     -1.398353e-02 -1.446694e-02 -1.496167e-02 -1.546770e-02 ......
## ASV5688      1.175230e-02  1.215851e-02  1.257423e-02  1.299944e-02 ......
## ASV5752      4.067120e-03  4.255664e-03  4.452174e-03  4.656892e-03 ......
## ASV6122     -1.505371e-02 -1.557401e-02 -1.610647e-02 -1.665109e-02 ......
## ASV6135      7.902020e-03  8.175090e-03  8.454545e-03  8.740376e-03 ......
## ASV6188     -4.797300e-02 -4.963053e-02 -5.132681e-02 -5.306177e-02 ......
## ASV6216      1.176100e-02  1.224081e-02  1.273758e-02  1.325175e-02 ......
## ASV6242      7.897867e-03  8.170641e-03  8.449783e-03  8.735283e-03 ......
## ASV6383      4.937719e-02  5.108229e-02  5.282718e-02  5.461179e-02 ......
## ASV6781      1.098779e-02  1.136716e-02  1.175538e-02  1.215244e-02 ......
## ASV6799     -2.086366e-02 -2.158389e-02 -2.232092e-02 -2.307471e-02 ......
## ASV7374     -4.426745e-03 -4.579536e-03 -4.735887e-03 -4.895794e-03 ......
## ASV7539     -5.905310e-03 -6.109101e-03 -6.317640e-03 -6.530918e-03 ......
## ASV8591     -1.502765e-02 -1.554617e-02 -1.607676e-02 -1.661941e-02 ......
## ASV8637      6.596498e-02  6.824068e-02  7.056935e-02  7.295091e-02 ......
## ASV12796    -8.704269e-03 -9.004507e-03 -9.311729e-03 -9.625926e-03 ......
## ASV1934      5.151025e-03  5.382810e-03  5.624471e-03  5.876383e-03 ......
## ASV22549     6.937248e-04  7.404328e-04  7.900738e-04  8.427980e-04 ......
## ASV29857    -3.376021e-03 -3.492464e-03 -3.611617e-03 -3.733475e-03 ......
## ASV3215      5.588327e-03  5.849895e-03  6.123545e-03  6.409820e-03 ......
## ASV3236     -8.701449e-03 -9.001513e-03 -9.308554e-03 -9.622563e-03 ......
## ASV3954     -8.699950e-03 -8.999914e-03 -9.306851e-03 -9.620749e-03 ......
## ASV4850      5.831378e-03  6.032404e-03  6.238102e-03  6.448462e-03 ......
## ASV5225      5.630484e-02  5.824554e-02  6.023130e-02  6.226207e-02 ......
## ASV5532     -3.007075e-03 -3.110706e-03 -3.216742e-03 -3.325180e-03 ......
## ASV7258      3.185551e-03  3.363317e-03  3.551251e-03  3.749921e-03 ......
## ASV9474     -6.485887e-04 -6.491283e-04 -6.478630e-04 -6.446365e-04 ......
## ASV11857    -1.129843e-02 -1.168784e-02 -1.208629e-02 -1.249379e-02 ......
## ASV1202     -7.174241e-03 -7.421467e-03 -7.674435e-03 -7.933138e-03 ......
## ASV14742     2.493116e-03  2.622780e-03  2.759302e-03  2.903037e-03 ......
## ASV16652     1.820791e-03  1.906371e-03  1.995571e-03  2.088494e-03 ......
## ASV2019      5.796484e-03  6.034709e-03  6.281476e-03  6.537010e-03 ......
## ASV2410     -1.341576e-02 -1.401419e-02 -1.463821e-02 -1.528885e-02 ......
## ASV2718      3.428112e-03  3.588057e-03  3.755157e-03  3.929695e-03 ......
## ASV2738      9.449422e-03  9.831388e-03  1.022634e-02  1.063454e-02 ......
## ASV2876      5.215270e-03  5.394927e-03  5.578755e-03  5.766745e-03 ......
## ASV3177      6.987759e-03  7.228437e-03  7.474698e-03  7.726535e-03 ......
## ASV4367      8.633688e-03  8.931008e-03  9.235223e-03  9.546322e-03 ......
## ASV4635      3.392799e-03  3.565810e-03  3.747324e-03  3.937695e-03 ......
## ASV4896      2.746053e-03  2.906289e-03  3.076084e-03  3.255990e-03 ......
## ASV4907      2.837704e-03  2.981592e-03  3.132772e-03  3.291598e-03 ......
## ASV5230     -6.722216e-03 -6.953828e-03 -7.190825e-03 -7.433200e-03 ......
## ASV6509     -7.169329e-03 -7.416306e-03 -7.669023e-03 -7.927473e-03 ......
## ASV7376     -5.128699e-03 -5.305349e-03 -5.486104e-03 -5.670957e-03 ......
## ASV8163     -7.641334e-03 -7.904487e-03 -8.173750e-03 -8.449116e-03 ......
## ASV8195     -6.717592e-03 -6.948895e-03 -7.185567e-03 -7.427601e-03 ......
## ASV8923      2.573519e-03  2.700893e-03  2.834394e-03  2.974282e-03 ......
## ASV9666     -3.140324e-03 -3.211678e-03 -3.281501e-03 -3.349497e-03 ......
## ASV1482      4.162620e-03  4.356279e-03  4.558590e-03  4.769899e-03 ......
## ASV2726      3.838680e-03  4.017857e-03  4.205035e-03  4.400528e-03 ......
## ASV3281     -2.798949e-02 -2.895337e-02 -2.993966e-02 -3.094832e-02 ......
## ASV4235     -2.798467e-02 -2.894824e-02 -2.993419e-02 -3.094249e-02 ......
## ASV4808      6.261481e-03  6.519828e-03  6.787703e-03  7.065397e-03 ......
## ASV4861     -1.523897e-02 -1.586255e-02 -1.650909e-02 -1.717932e-02 ......
## ASV5276      8.909858e-03  9.274444e-03  9.652077e-03  1.004311e-02 ......
## ASV5837      3.078242e-03  3.220634e-03  3.369503e-03  3.525137e-03 ......
## ASV7098      4.392388e-03  4.592619e-03  4.801699e-03  5.019997e-03 ......
## ASV8451     -4.760040e-03 -4.923741e-03 -5.091228e-03 -5.262495e-03 ......
## ASV8694     -2.795396e-02 -2.891516e-02 -2.989858e-02 -3.090419e-02 ......
## ASV0905     -1.435606e-03 -1.500641e-03 -1.568172e-03 -1.638241e-03 ......
## ASV2900      6.793105e-03  7.053355e-03  7.321795e-03  7.598597e-03 ......
## ASV3963     -6.802882e-03 -7.055711e-03 -7.316009e-03 -7.583913e-03 ......
## ASV0041     -1.338935e-03 -1.400919e-03 -1.465646e-03 -1.533225e-03 ......
## ASV1865      4.047251e-03  4.242021e-03  4.445912e-03  4.659313e-03 ......
## ASV1140      2.233291e-03  2.336635e-03  2.444402e-03  2.556741e-03 ......
## ASV1179      2.257383e-03  2.358064e-03  2.462896e-03  2.572018e-03 ......
## ASV0279      3.379613e-03  3.526256e-03  3.678792e-03  3.837426e-03 ......
## ASV0043     -6.551101e-04 -6.893394e-04 -7.254472e-04 -7.635411e-04 ......
## ASV2097     -1.953681e-03 -2.033618e-03 -2.116533e-03 -2.202530e-03 ......
## ASV0309     -3.921305e-04 -4.085212e-04 -4.255233e-04 -4.431552e-04 ......
## ASV0607      5.409567e-03  5.654712e-03  5.910406e-03  6.177055e-03 ......
## ASV0025     -1.511948e-03 -1.580989e-03 -1.653017e-03 -1.728144e-03 ......
## ASV2284     -5.443609e-03 -5.655019e-03 -5.873270e-03 -6.098520e-03 ......
## ASV0556      1.594085e-03  1.672003e-03  1.753660e-03  1.839221e-03 ......
## ASV5040     -6.958063e-03 -7.407416e-03 -7.885178e-03 -8.392960e-03 ......
## ASV2924     -1.715025e-02 -1.778958e-02 -1.844752e-02 -1.912432e-02 ......
## ASV1331      4.742414e-03  4.952818e-03  5.171972e-03  5.400194e-03 ......
## ASV0506     -1.891666e-03 -1.959907e-03 -2.029768e-03 -2.101223e-03 ......
## ASV1514      7.177602e-03  7.494344e-03  7.823932e-03  8.166787e-03 ......
## ASV2144      6.841256e-03  7.143594e-03  7.458395e-03  7.786105e-03 ......
## ASV2265      4.514435e-03  4.714933e-03  4.923722e-03  5.141093e-03 ......
## ASV5156      3.042250e-03  3.141463e-03  3.242326e-03  3.344764e-03 ......
## ASV5534      8.616265e-04  8.834018e-04  9.049008e-04  9.260425e-04 ......
## ASV5747     -2.091827e-03 -2.261363e-03 -2.443273e-03 -2.638304e-03 ......
## ASV6657      3.363175e-03  3.499796e-03  3.641130e-03  3.787283e-03 ......
## ASV0658     -2.423058e-03 -2.514126e-03 -2.607726e-03 -2.703864e-03 ......
## ASV0716      4.532372e-03  4.719141e-03  4.912427e-03  5.112365e-03 ......
## ASV1657      8.487861e-03  8.814112e-03  9.150070e-03  9.495825e-03 ......
## ASV1885      6.819151e-03  7.049469e-03  7.284075e-03  7.522793e-03 ......
## ASV2333      4.004756e-03  4.176833e-03  4.355586e-03  4.541220e-03 ......
## ASV3375      3.001788e-03  3.121015e-03  3.244237e-03  3.371549e-03 ......
## ASV4317      2.859674e-03  2.989895e-03  3.125911e-03  3.267977e-03 ......
## ASV9599     -8.782615e-04 -9.494279e-04 -1.025787e-03 -1.107653e-03 ......
## ASV0175     -4.299831e-03 -4.479535e-03 -4.665687e-03 -4.858428e-03 ......
## ASV1032      1.746938e-03  1.813835e-03  1.882719e-03  1.953611e-03 ......
## ASV1235      2.949372e-03  3.043905e-03  3.139632e-03  3.236418e-03 ......
## ASV1262      4.485262e-03  4.678642e-03  4.879550e-03  5.088217e-03 ......
## ASV1320      2.823934e-03  2.964854e-03  3.112840e-03  3.268233e-03 ......
## ASV13797     2.559482e-03  2.667000e-03  2.778574e-03  2.894328e-03 ......
## ASV1491      4.143757e-03  4.351029e-03  4.568342e-03  4.796112e-03 ......
## ASV15014    -6.826819e-04 -7.379739e-04 -7.972974e-04 -8.608953e-04 ......
## ASV1510      5.451700e-03  5.707644e-03  5.975019e-03  6.254259e-03 ......
## ASV1551      1.790989e-02  1.871016e-02  1.954387e-02  2.041221e-02 ......
## ASV1919      2.685101e-03  2.857822e-03  3.041363e-03  3.236310e-03 ......
## ASV2114      3.123938e-03  3.250497e-03  3.381576e-03  3.517312e-03 ......
## ASV21486    -5.859355e-04 -6.333639e-04 -6.842472e-04 -7.387930e-04 ......
## ASV2448      3.281856e-03  3.418406e-03  3.559924e-03  3.706541e-03 ......
## ASV2589      5.999750e-03  6.233844e-03  6.475345e-03  6.724380e-03 ......
## ASV2608      4.197661e-03  4.375931e-03  4.561013e-03  4.753114e-03 ......
## ASV2786      8.600658e-03  8.983893e-03  9.383593e-03  9.800446e-03 ......
## ASV2827      2.944624e-03  3.066992e-03  3.193745e-03  3.324986e-03 ......
## ASV2872      1.253004e-02  1.302895e-02  1.354384e-02  1.407491e-02 ......
## ASV3125      2.441084e-03  2.538303e-03  2.638737e-03  2.742451e-03 ......
## ASV3247      5.399338e-03  5.617673e-03  5.843428e-03  6.076758e-03 ......
## ASV3451     -1.815617e-03 -1.962584e-03 -2.120257e-03 -2.289281e-03 ......
## ASV3465     -1.509466e-04 -1.784271e-04 -2.085582e-04 -2.415294e-04 ......
## ASV3809      7.220433e-03  7.508259e-03  7.805538e-03  8.112439e-03 ......
## ASV4006      3.551366e-03  3.695332e-03  3.844185e-03  3.998024e-03 ......
## ASV4046      5.218054e-03  5.430214e-03  5.649728e-03  5.876766e-03 ......
## ASV4938     -7.412199e-05 -1.120493e-04 -1.539580e-04 -2.001269e-04 ......
## ASV5435     -3.079350e-03 -3.328479e-03 -3.595743e-03 -3.882229e-03 ......
## ASV5605      2.685882e-03  2.771020e-03  2.857138e-03  2.944103e-03 ......
## ASV5635     -1.026871e-03 -1.109923e-03 -1.199017e-03 -1.294516e-03 ......
## ASV5743      2.521557e-03  2.626921e-03  2.736182e-03  2.849453e-03 ......
## ASV6627     -1.065609e-03 -1.151780e-03 -1.244220e-03 -1.343302e-03 ......
## ASV6785     -1.185969e-03 -1.281853e-03 -1.384708e-03 -1.494952e-03 ......
## ASV7368      3.249897e-03  3.395343e-03  3.546986e-03  3.705067e-03 ......
## ASV9118      1.002147e-03  1.035272e-03  1.069007e-03  1.103335e-03 ......
## ASV9135      1.762245e-03  1.811944e-03  1.861658e-03  1.911261e-03 ......
## ASV9435      2.307861e-03  2.387285e-03  2.468269e-03  2.550753e-03 ......
## ASV9671     -1.520435e-03 -1.643318e-03 -1.775130e-03 -1.916406e-03 ......
## ASV0387     -4.276440e-03 -4.441913e-03 -4.612362e-03 -4.787833e-03 ......
## ASV0454     -7.003182e-03 -7.284338e-03 -7.574773e-03 -7.874642e-03 ......
## ASV0751     -1.886269e-03 -1.953268e-03 -2.021784e-03 -2.091789e-03 ......
## ASV1081      4.440829e-03  4.633553e-03  4.833775e-03  5.041713e-03 ......
## ASV1332      7.721641e-03  8.044195e-03  8.378389e-03  8.724502e-03 ......
## ASV2659      8.799737e-03  9.185081e-03  9.585632e-03  1.000184e-02 ......
## ASV2979      3.678013e-03  3.822597e-03  3.971685e-03  4.125331e-03 ......
## ASV4184      4.970777e-03  5.144161e-03  5.321195e-03  5.501779e-03 ......
## ASV6198      1.703796e-03  1.772743e-03  1.844190e-03  1.918221e-03 ......
## ASV7454      1.799111e-03  1.869229e-03  1.941494e-03  2.015930e-03 ......
## ASV8198      1.287964e-03  1.319597e-03  1.350672e-03  1.381050e-03 ......
## ASV0855      4.797012e-03  5.007657e-03  5.226834e-03  5.454835e-03 ......
## ASV10092     2.071420e-03  2.154237e-03  2.239837e-03  2.328279e-03 ......
## ASV1532      4.429397e-03  4.635409e-03  4.850747e-03  5.075810e-03 ......
## ASV2553      7.662480e-03  8.000331e-03  8.351986e-03  8.717923e-03 ......
## ASV2741      1.086544e-02  1.137066e-02  1.189840e-02  1.244954e-02 ......
## ASV4095      6.720510e-03  7.045996e-03  7.386546e-03  7.742745e-03 ......
## ASV5295      1.993008e-03  2.064524e-03  2.137727e-03  2.212589e-03 ......
## ASV5787     -6.248246e-04 -6.752851e-04 -7.294080e-04 -7.874121e-04 ......
## ASV9455      2.853333e-03  2.971585e-03  3.094203e-03  3.221322e-03 ......
## ASV10879     2.660806e-03  2.775047e-03  2.893816e-03  3.017275e-03 ......
## ASV3997      3.699015e-03  3.874278e-03  4.057433e-03  4.248778e-03 ......
## ASV6760      6.160043e-04  6.161137e-04  6.142888e-04  6.103457e-04 ......
## ASV6990      2.623375e-03  2.727656e-03  2.835432e-03  2.946784e-03 ......
## ASV9560      1.603275e-03  1.662163e-03  1.722685e-03  1.784860e-03 ......
## ASV0220     -4.137003e-04 -4.315581e-04 -4.501153e-04 -4.693935e-04 ......
## ASV2518      1.748711e-03  1.825951e-03  1.906349e-03  1.990017e-03 ......
## ASV3615      4.317480e-03  4.501272e-03  4.692062e-03  4.890053e-03 ......
## ASV0075     -2.233742e-05 -2.383597e-05 -2.542800e-05 -2.711830e-05 ......
## ASV8070      6.471367e-05  5.730964e-05  4.886262e-05  3.929038e-05 ......
## ASV1658      1.652416e-03  1.718271e-03  1.786310e-03  1.856575e-03 ......
## ASV0773      3.092438e-03  3.219271e-03  3.350571e-03  3.486445e-03 ......
## ASV0799      2.982275e-04  3.063200e-04  3.142994e-04  3.221246e-04 ......
## ASV1839     -2.162329e-03 -2.252087e-03 -2.344976e-03 -2.441052e-03 ......
## ASV0265      2.711875e-03  2.839460e-03  2.972885e-03  3.112397e-03 ......
## ASV3741      8.540287e-04  8.848159e-04  9.162398e-04  9.482674e-04 ......
## ASV0847      3.589987e-03  3.749137e-03  3.914850e-03  4.087359e-03 ......
## ASV1026      4.628148e-03  4.826668e-03  5.032779e-03  5.246697e-03 ......
## ASV1222     -1.031492e-03 -1.061195e-03 -1.090988e-03 -1.120804e-03 ......
## ASV0729     -7.831773e-05 -8.199945e-05 -8.585428e-05 -8.989049e-05 ......
## ASV0143     -1.128087e-03 -1.173724e-03 -1.220922e-03 -1.269715e-03 ......
## ASV1328      6.698950e-04  7.061500e-04  7.444102e-04  7.847802e-04 ......
## ASV9078     -1.591797e-03 -1.682617e-03 -1.778674e-03 -1.880249e-03 ......
## ASV0027     -1.421848e-03 -1.486479e-03 -1.553880e-03 -1.624152e-03 ......
## ASV0546     -1.519354e-03 -1.579565e-03 -1.641783e-03 -1.706053e-03 ......
## ASV1136      3.889533e-03  4.060030e-03  4.237469e-03  4.422096e-03 ......
## ASV3081      2.066748e-03  2.159657e-03  2.256607e-03  2.357769e-03 ......
## ASV0531      7.090504e-04  7.475111e-04  7.881095e-04  8.309613e-04 ......
## ASV2525      2.937618e-03  3.058567e-03  3.183792e-03  3.313394e-03 ......
## ASV1083     -5.101620e-04 -5.256259e-04 -5.412427e-04 -5.569921e-04 ......
## ASV0424     -4.460120e-04 -4.663440e-04 -4.875468e-04 -5.096514e-04 ......
## ASV0644      4.387074e-04  4.741325e-04  5.121282e-04  5.528479e-04 ......
## ASV6007     -4.421137e-04 -4.781584e-04 -5.168672e-04 -5.584059e-04 ......
## ASV0564      1.509151e-03  1.579824e-03  1.653658e-03  1.730776e-03 ......
## ASV1938      4.126531e-03  4.277858e-03  4.433027e-03  4.592007e-03 ......
## ASV6516     -7.166772e-03 -7.487956e-03 -7.822754e-03 -8.171686e-03 ......
## ASV0503     -2.600773e-03 -2.698473e-03 -2.798862e-03 -2.901945e-03 ......
## ASV6913     -1.393307e-02 -1.453525e-02 -1.516169e-02 -1.581327e-02 ......
## ASV0164     -1.798748e-03 -1.881090e-03 -1.967057e-03 -2.056797e-03 ......
## ASV1576      4.961397e-03  5.178711e-03  5.404987e-03  5.640563e-03 ......
## ASV1725      2.616705e-03  2.741991e-03  2.873041e-03  3.010086e-03 ......
## ASV4501      1.119687e-03  1.153936e-03  1.188411e-03  1.223034e-03 ......
## ASV10678    -6.569534e-03 -6.860940e-03 -7.164402e-03 -7.480350e-03 ......
## ASV0944      1.091679e-03  1.144194e-03  1.199241e-03  1.256942e-03 ......
## ASV2292      5.169873e-03  5.387729e-03  5.613663e-03  5.847891e-03 ......
## ASV1090      2.101522e-03  2.191906e-03  2.285831e-03  2.383411e-03 ......
## ASV9117     -1.256108e-03 -1.296208e-03 -1.336911e-03 -1.378177e-03 ......
## ASV0285     -2.979332e-03 -3.139956e-03 -3.309313e-03 -3.487854e-03 ......
## ASV0463     -1.386510e-03 -1.438749e-03 -1.492385e-03 -1.547409e-03 ......
## ASV3199      1.739409e-03  1.803806e-03  1.869902e-03  1.937695e-03 ......
## ASV0150     -3.624882e-04 -3.825892e-04 -4.038018e-04 -4.261819e-04 ......
## ASV6583     -1.451683e-03 -1.506711e-03 -1.563571e-03 -1.622328e-03 ......
## ASV0392      1.356489e-04  1.398042e-04  1.439853e-04  1.481832e-04 ......
## ASV14007    -2.311866e-03 -2.408298e-03 -2.508180e-03 -2.611588e-03 ......
## ASV0177     -1.076522e-03 -1.120661e-03 -1.166329e-03 -1.213557e-03 ......
## ASV6448     -1.995200e-03 -2.101561e-03 -2.213618e-03 -2.331657e-03 ......
## ASV5399     -1.141541e-02 -1.197587e-02 -1.256350e-02 -1.317952e-02 ......
## ASV0277     -2.311302e-04 -2.397734e-04 -2.485993e-04 -2.575945e-04 ......
## ASV2599      5.443668e-04  5.132816e-04  4.771598e-04  4.356217e-04 ......
## ASV13465    -5.737042e-04 -5.851739e-04 -5.961683e-04 -6.066156e-04 ......
## ASV2412      6.248703e-04  6.528563e-04  6.820249e-04  7.124204e-04 ......
## ASV0423     -1.482852e-04 -1.489372e-04 -1.491003e-04 -1.487130e-04 ......
## ASV5187      2.710962e-03  2.795588e-03  2.881239e-03  2.967799e-03 ......
## ASV0701     -2.150564e-03 -2.248291e-03 -2.350253e-03 -2.456614e-03 ......
## ASV4248      1.259546e-03  1.322843e-03  1.389280e-03  1.459002e-03 ......
## ASV0519      2.065531e-03  2.161472e-03  2.261673e-03  2.366299e-03 ......
## ASV0764      5.544132e-04  5.806163e-04  6.079961e-04  6.365968e-04 ......
## ASV5385     -1.833643e-03 -1.918679e-03 -2.007569e-03 -2.100484e-03 ......
## ASV3021     -2.669383e-03 -2.762259e-03 -2.857293e-03 -2.954474e-03 ......
## ASV4119     -7.830651e-03 -8.175750e-03 -8.535387e-03 -8.910152e-03 ......
## ASV2534     -4.772952e-04 -5.085492e-04 -5.418042e-04 -5.771760e-04 ......
## ASV1061      2.206037e-03  2.319610e-03  2.439186e-03  2.565085e-03 ......
## ASV0670     -5.388093e-04 -5.628316e-04 -5.878432e-04 -6.138766e-04 ......
## ASV1384      2.513201e-03  2.637270e-03  2.767292e-03  2.903523e-03 ......
## ASV1981      5.789070e-03  6.057397e-03  6.337691e-03  6.630436e-03 ......
## ASV9632     -8.375341e-04 -8.533534e-04 -8.684574e-04 -8.827528e-04 ......
## ASV4564      1.661450e-03  1.735157e-03  1.811846e-03  1.891609e-03 ......
## ASV5289     -1.129091e-03 -1.186466e-03 -1.246865e-03 -1.310452e-03 ......
## ASV0516      3.916141e-03  4.089019e-03  4.268905e-03  4.456027e-03 ......
## ASV1463     -5.482292e-03 -5.724283e-03 -5.976204e-03 -6.238407e-03 ......
## ASV0969      1.845788e-04  1.905779e-04  1.966264e-04  2.027083e-04 ......
## ASV1113     -1.262617e-03 -1.319190e-03 -1.378152e-03 -1.439590e-03 ......
## ASV1234     -1.783196e-03 -1.883684e-03 -1.990199e-03 -2.103113e-03 ......
## ASV3814     -1.368602e-03 -1.461037e-03 -1.559512e-03 -1.664376e-03 ......
## ASV1000      2.430866e-03  2.532328e-03  2.637415e-03  2.746205e-03 ......
## ASV0079     -3.226488e-04 -3.408014e-04 -3.600135e-04 -3.803463e-04 ......
## ASV0145      3.634835e-04  3.728850e-04  3.822276e-04  3.914852e-04 ......
## ASV0457     -3.197380e-03 -3.333792e-03 -3.475396e-03 -3.622341e-03 ......
## ASV1485      2.802097e-04  2.942021e-04  3.089115e-04  3.243752e-04 ......
## ASV0535      1.120472e-03  1.179170e-03  1.240941e-03  1.305935e-03 ......
## ASV0259     -1.805169e-03 -1.883451e-03 -1.964761e-03 -2.049183e-03 ......
## ASV0570      6.176615e-04  6.495136e-04  6.830511e-04  7.183627e-04 ......
## ASV0906      2.015209e-03  2.098603e-03  2.184951e-03  2.274320e-03 ......
## ASV1748      1.410375e-03  1.426587e-03  1.439763e-03  1.449514e-03 ......
## ASV5520     -3.107124e-03 -3.269907e-03 -3.441197e-03 -3.621400e-03 ......
## ASV2288     -6.898620e-03 -7.205133e-03 -7.524365e-03 -7.856771e-03 ......
## ASV1887     -1.719562e-03 -1.816267e-03 -1.918224e-03 -2.025675e-03 ......
## ASV0374     -2.392721e-04 -2.463071e-04 -2.533785e-04 -2.604723e-04 ......
## ASV0823      3.842992e-03  4.000284e-03  4.163143e-03  4.331711e-03 ......
## ASV0717      3.036257e-04  3.172827e-04  3.315124e-04  3.463350e-04 ......
## ASV0431     -8.447711e-04 -8.843962e-04 -9.258390e-04 -9.691781e-04 ......
## ASV1030      9.681093e-03  1.013351e-02  1.060650e-02  1.110092e-02 ......
## ASV1082     -1.242491e-03 -1.299121e-03 -1.358209e-03 -1.419849e-03 ......
## ASV2684      3.311448e-04  3.546081e-04  3.794846e-04  4.058301e-04 ......
## ASV0051      1.182788e-03  1.236718e-03  1.293017e-03  1.351779e-03 ......
## ASV0513     -3.397617e-04 -3.526706e-04 -3.659190e-04 -3.795016e-04 ......
## ASV0581      2.140469e-03  2.236246e-03  2.336007e-03  2.439890e-03 ......
## ASV7282      8.567393e-04  9.080888e-04  9.627039e-04  1.020798e-03 ......
## ASV3009     -1.827467e-03 -1.909077e-03 -1.994092e-03 -2.082633e-03 ......
## ASV2106      2.519882e-03  2.658635e-03  2.805232e-03  2.960109e-03 ......
## ASV1012      1.581412e-03  1.654412e-03  1.730582e-03  1.810036e-03 ......
## ASV0921      1.641133e-03  1.721176e-03  1.805173e-03  1.893322e-03 ......
## ASV0010     -9.259644e-04 -9.681465e-04 -1.012148e-03 -1.058037e-03 ......
## ASV1178      4.334908e-04  4.538766e-04  4.751406e-04  4.973091e-04 ......
## ASV2848     -2.388761e-03 -2.491874e-03 -2.599148e-03 -2.710734e-03 ......
## ASV0586      6.272760e-03  6.568219e-03  6.877427e-03  7.201007e-03 ......
## ASV4225     -7.109779e-03 -7.294791e-03 -7.479117e-03 -7.662320e-03 ......
## ASV2156     -3.485172e-03 -3.646038e-03 -3.814084e-03 -3.989609e-03 ......
## ASV9778     -2.474583e-03 -2.586555e-03 -2.703349e-03 -2.825153e-03 ......
## ASV0493     -4.902415e-03 -5.113255e-03 -5.332390e-03 -5.560097e-03 ......
## ASV3770     -8.531620e-04 -9.084134e-04 -9.671650e-04 -1.029615e-03 ......
## ASV0470      3.529117e-03  3.688795e-03  3.855366e-03  4.029106e-03 ......
## ASV0262     -1.659019e-03 -1.745069e-03 -1.835630e-03 -1.930931e-03 ......
## ASV0998      9.359674e-04  9.795144e-04  1.025039e-03  1.072626e-03 ......
## ASV7708     -3.990947e-04 -4.134350e-04 -4.280692e-04 -4.429817e-04 ......
## ASV0453     -3.608473e-04 -3.773183e-04 -3.945533e-04 -4.125910e-04 ......
## ASV0044      1.459587e-03  1.524156e-03  1.591371e-03  1.661323e-03 ......
## ASV5490      7.600450e-04  7.872210e-04  8.148827e-04  8.429840e-04 ......
## ASV2638     -4.380387e-04 -4.549470e-04 -4.725346e-04 -4.908475e-04 ......
## ASV0829      5.001132e-03  5.217195e-03  5.441317e-03  5.673672e-03 ......
## ASV0601      1.751440e-03  1.834755e-03  1.921973e-03  2.013266e-03 ......
## ASV0234      1.457611e-04  1.536949e-04  1.620917e-04  1.709803e-04 ......
## ASV0133      2.586269e-03  2.703106e-03  2.824940e-03  2.951959e-03 ......
## ASV0323      8.896428e-04  9.331795e-04  9.788814e-04  1.026858e-03 ......
## ASV0854     -5.789380e-04 -6.044071e-04 -6.309132e-04 -6.584922e-04 ......
## ASV0110      1.640921e-03  1.715999e-03  1.794380e-03  1.876198e-03 ......
## ASV0816     -1.660742e-04 -1.739116e-04 -1.821074e-04 -1.906764e-04 ......
## ASV1031     -5.622752e-04 -5.846968e-04 -6.079003e-04 -6.319097e-04 ......
## ASV0144     -7.766286e-04 -8.138202e-04 -8.528043e-04 -8.936677e-04 ......
## ASV0020     -3.781741e-04 -3.975968e-04 -4.180655e-04 -4.396396e-04 ......
## ASV0962     -9.548150e-04 -9.968148e-04 -1.040503e-03 -1.085932e-03 ......
## ASV0794      1.920348e-03  2.014957e-03  2.114142e-03  2.218105e-03 ......
## ASV7117     -1.645677e-03 -1.716548e-03 -1.790185e-03 -1.866674e-03 ......
## ASV1008     -8.483612e-04 -8.892666e-04 -9.321445e-04 -9.770885e-04 ......
## ASV0096      2.098030e-03  2.193799e-03  2.293758e-03  2.398077e-03 ......
## ASV0128     -3.551308e-03 -3.720868e-03 -3.898502e-03 -4.084587e-03 ......
## ASV5232      3.319365e-03  3.480644e-03  3.649684e-03  3.826839e-03 ......
## ASV0031     -2.498052e-04 -2.614061e-04 -2.735227e-04 -2.861754e-04 ......
## ASV1744     -3.418902e-03 -3.581133e-03 -3.751173e-03 -3.929412e-03 ......
## ASV0289      9.434577e-04  9.864436e-04  1.031317e-03  1.078155e-03 ......
## ASV7413     -6.922810e-04 -7.346394e-04 -7.796131e-04 -8.273515e-04 ......
## ASV0822     -4.001980e-03 -4.170830e-03 -4.345965e-03 -4.527557e-03 ......
## ASV8111     -6.643678e-03 -6.928840e-03 -7.225374e-03 -7.533690e-03 ......
## ASV0687      9.210678e-04  9.645868e-04  1.010098e-03  1.057684e-03 ......
## ASV0112     -3.391383e-04 -3.554454e-04 -3.725295e-04 -3.904259e-04 ......
## ASV0987      1.148309e-03  1.203691e-03  1.261752e-03  1.322620e-03 ......
## ASV5332     -5.137123e-04 -5.264351e-04 -5.392436e-04 -5.521451e-04 ......
## ASV1129     -2.043487e-03 -2.137244e-03 -2.235178e-03 -2.337465e-03 ......
## ASV1274     -5.584901e-04 -5.835629e-04 -6.097026e-04 -6.369502e-04 ......
## ASV0119      1.358550e-03  1.420408e-03  1.484960e-03  1.552314e-03 ......
## ASV0890     -8.215379e-05 -8.691582e-05 -9.200081e-05 -9.743449e-05 ......
## ASV0848     -2.522506e-03 -2.637431e-03 -2.757384e-03 -2.882572e-03 ......
## ASV5944     -1.087882e-02 -1.135758e-02 -1.185583e-02 -1.237426e-02 ......
## ASV19741    -3.990418e-03 -4.167940e-03 -4.352867e-03 -4.545471e-03 ......
## ASV0504     -4.900995e-03 -5.109474e-03 -5.325929e-03 -5.550605e-03 ......
## ASV2146     -3.461298e-03 -3.603402e-03 -3.750642e-03 -3.903163e-03 ......
## ASV0089     -8.520386e-04 -8.899643e-04 -9.294504e-04 -9.705492e-04 ......
## ASV2301     -1.411815e-03 -1.477177e-03 -1.545470e-03 -1.616814e-03 ......
## ASV2982     -2.065624e-02 -2.134333e-02 -2.204444e-02 -2.275936e-02 ......
## ASV0891     -1.619013e-03 -1.691749e-03 -1.767568e-03 -1.846586e-03 ......
## ASV0093      1.755160e-03  1.832996e-03  1.914053e-03  1.998446e-03 ......
## ASV0042      6.254273e-04  6.539981e-04  6.838265e-04  7.149643e-04 ......
## ASV0980      1.887336e-03  1.962638e-03  2.040308e-03  2.120363e-03 ......
## ASV0069     -9.525454e-04 -9.957362e-04 -1.040780e-03 -1.087746e-03 ......
## ASV1364     -7.127729e-04 -7.437235e-04 -7.758912e-04 -8.093134e-04 ......
## ASV0524     -3.724635e-03 -3.898536e-03 -4.080374e-03 -4.270494e-03 ......
## ASV0435      5.060102e-03  5.293076e-03  5.536421e-03  5.790568e-03 ......
## ASV0517     -9.946790e-04 -1.040181e-03 -1.087687e-03 -1.137278e-03 ......
## ASV3167     -7.796695e-03 -8.196597e-03 -8.617185e-03 -9.059492e-03 ......
## ASV4280     -4.513827e-03 -4.717834e-03 -4.930653e-03 -5.152635e-03 ......
## ASV1158      1.733291e-03  1.819381e-03  1.909546e-03  2.003945e-03 ......
## ASV2214      1.457254e-03  1.520586e-03  1.586673e-03  1.655655e-03 ......
## ASV0544     -2.529571e-03 -2.649714e-03 -2.775512e-03 -2.907226e-03 ......
## ASV5326     -3.624673e-04 -3.804808e-04 -3.994227e-04 -4.193436e-04 ......
## ASV3765     -1.900325e-03 -1.985181e-03 -2.073577e-03 -2.165637e-03 ......
## ASV4646     -1.454782e-04 -1.631687e-04 -1.823790e-04 -2.032095e-04 ......
## ASV0090      1.279746e-04  1.321194e-04  1.363015e-04  1.405111e-04 ......
## ASV3680      2.939783e-03  3.055700e-03  3.175201e-03  3.298316e-03 ......
## ASV0111      3.167312e-04  3.298506e-04  3.434336e-04  3.574903e-04 ......
## ASV0768      5.012060e-04  5.258907e-04  5.518176e-04  5.790507e-04 ......
## ASV4862     -1.965369e-04 -1.992469e-04 -2.015049e-04 -2.032416e-04 ......
## ASV1742     -2.708286e-03 -2.825350e-03 -2.947079e-03 -3.073632e-03 ......
## ASV3701     -8.997961e-04 -9.311477e-04 -9.632055e-04 -9.959571e-04 ......
## ASV2386     -5.398815e-03 -5.648822e-03 -5.909878e-03 -6.182410e-03 ......
## ASV0375     -3.665200e-03 -3.825063e-03 -3.991417e-03 -4.164495e-03 ......
## ASV2796      1.198507e-03  1.246486e-03  1.296175e-03  1.347632e-03 ......
## ASV1369      2.774449e-03  2.892915e-03  3.016291e-03  3.144795e-03 ......
## ASV10272    -4.196986e-03 -4.382674e-03 -4.575922e-03 -4.776978e-03 ......
## ASV10354    -6.249158e-03 -6.525575e-03 -6.813238e-03 -7.112517e-03 ......
## ASV1067      2.027462e-03  2.116050e-03  2.208209e-03  2.304061e-03 ......
## ASV1900      3.432729e-03  3.590569e-03  3.755408e-03  3.927533e-03 ......
## ASV4079     -1.668790e-03 -1.752583e-03 -1.840562e-03 -1.932919e-03 ......
## ASV4149      6.272585e-03  6.525955e-03  6.787755e-03  7.058129e-03 ......
## ASV5140     -6.248111e-03 -6.524428e-03 -6.811983e-03 -7.111144e-03 ......
## ASV10782     3.538861e-04  3.809105e-04  4.101133e-04  4.416710e-04 ......
## ASV4273     -4.719727e-04 -4.827921e-04 -4.930937e-04 -5.027671e-04 ......
## ASV8121      2.846386e-03  2.975487e-03  3.110221e-03  3.250819e-03 ......
## ASV8438     -7.107823e-03 -7.422124e-03 -7.749205e-03 -8.089486e-03 ......
## ASV9390     -7.106161e-03 -7.420312e-03 -7.747230e-03 -8.087335e-03 ......
## ASV1340      5.854165e-03  6.122910e-03  6.403500e-03  6.696408e-03 ......
## ASV2650     -1.310231e-02 -1.367376e-02 -1.426781e-02 -1.488514e-02 ......
## ASV4674      3.501497e-03  3.654529e-03  3.813632e-03  3.978990e-03 ......
## ASV10492     7.438513e-06  3.883431e-06 -1.705496e-07 -4.772488e-06 ......
## ASV11430    -5.421650e-03 -5.661257e-03 -5.910595e-03 -6.169983e-03 ......
## ASV12135    -5.420382e-03 -5.659875e-03 -5.909089e-03 -6.168343e-03 ......
## ASV14970    -6.664576e-03 -6.958970e-03 -7.265308e-03 -7.583980e-03 ......
## ASV1954      8.136439e-03  8.499213e-03  8.877048e-03  9.270472e-03 ......
## ASV2613      5.107555e-03  5.332623e-03  5.566845e-03  5.810531e-03 ......
## ASV2757      3.030711e-03  3.154046e-03  3.281585e-03  3.413413e-03 ......
## ASV2909     -9.863624e-03 -1.032592e-02 -1.080949e-02 -1.131528e-02 ......
## ASV2954     -3.609429e-04 -3.769892e-04 -3.936860e-04 -4.110540e-04 ......
## ASV2969      2.499321e-03  2.614772e-03  2.735392e-03  2.861397e-03 ......
## ASV3410      9.085223e-04  9.523788e-04  9.983825e-04  1.046641e-03 ......
## ASV3575      1.625827e-03  1.696302e-03  1.769608e-03  1.845845e-03 ......
## ASV4275      4.078807e-03  4.247731e-03  4.422605e-03  4.603554e-03 ......
## ASV4652      9.491902e-04  9.940595e-04  1.041022e-03  1.090170e-03 ......
## ASV4761      2.943689e-03  3.064325e-03  3.189055e-03  3.317945e-03 ......
## ASV6003      2.378080e-03  2.493261e-03  2.614072e-03  2.740790e-03 ......
## ASV6110     -1.529727e-02 -1.597333e-02 -1.667686e-02 -1.740874e-02 ......
## ASV7427      2.606192e-03  2.717859e-03  2.833803e-03  2.954147e-03 ......
## ASV8092     -5.015792e-03 -5.237429e-03 -5.468064e-03 -5.707994e-03 ......
## ASV8169     -1.529130e-02 -1.596683e-02 -1.666977e-02 -1.740101e-02 ......
## ASV9693      2.578830e-03  2.691549e-03  2.808728e-03  2.930501e-03 ......
## ASV10913     1.791910e-03  1.874932e-03  1.961686e-03  2.052329e-03 ......
## ASV1979      1.499690e-03  1.562720e-03  1.628009e-03  1.695602e-03 ......
## ASV3772      3.102278e-03  3.233847e-03  3.370375e-03  3.512005e-03 ......
## ASV0113     -4.381273e-04 -4.582656e-04 -4.792860e-04 -5.012226e-04 ......
## ASV1800     -5.814798e-04 -6.082085e-04 -6.360825e-04 -6.651412e-04 ......
## ASV2335     -1.161950e-02 -1.212870e-02 -1.265889e-02 -1.321088e-02 ......
## ASV0692     -8.773310e-05 -9.235079e-05 -9.723835e-05 -1.024142e-04 ......
## ASV1120      4.427191e-04  4.637984e-04  4.858827e-04  5.090204e-04 ......
## ASV1434     -2.145254e-03 -2.243208e-03 -2.345454e-03 -2.452165e-03 ......
## ASV0076     -1.000613e-03 -1.045860e-03 -1.093038e-03 -1.142218e-03 ......
## ASV0361      3.605983e-03  3.771898e-03  3.945191e-03  4.126167e-03 ......
## ASV2231     -1.251459e-03 -1.315635e-03 -1.383206e-03 -1.454352e-03 ......
## ASV2018     -2.880082e-04 -3.011940e-04 -3.149693e-04 -3.293602e-04 ......
## ASV1529      1.596206e-03  1.672189e-03  1.751771e-03  1.835119e-03 ......
## ASV0841     -5.330453e-04 -5.566752e-04 -5.812806e-04 -6.068959e-04 ......
## ASV2556     -9.888624e-03 -1.033435e-02 -1.079902e-02 -1.128333e-02 ......
## ASV2777      2.988813e-03  3.103023e-03  3.220438e-03  3.341055e-03 ......
## ASV0355      2.457868e-03  2.568440e-03  2.683727e-03  2.803910e-03 ......
## ASV5169     -2.921273e-03 -3.050952e-03 -3.185954e-03 -3.326458e-03 ......
## ASV3091      2.837214e-03  2.969904e-03  3.108686e-03  3.253829e-03 ......
## ASV2435      1.106699e-03  1.155368e-03  1.205992e-03  1.258633e-03 ......
## ASV6822     -6.009563e-03 -6.275326e-03 -6.551900e-03 -6.839641e-03 ......
## ASV12605    -5.967466e-03 -6.240484e-03 -6.525467e-03 -6.822890e-03 ......
## ASV0286     -1.417420e-03 -1.481606e-03 -1.548617e-03 -1.618574e-03 ......
## ASV0074     -5.692999e-04 -5.955216e-04 -6.229019e-04 -6.514874e-04 ......
## ASV2485     -2.937416e-04 -3.117907e-04 -3.310821e-04 -3.517076e-04 ......
## ASV1233     -4.495719e-03 -4.702982e-03 -4.919534e-03 -5.145769e-03 ......
## ASV0356     -1.153801e-03 -1.204458e-03 -1.257202e-03 -1.312113e-03 ......
## ASV2918     -4.901428e-03 -5.119393e-03 -5.346434e-03 -5.582883e-03 ......
## ASV1427     -6.605449e-04 -6.936292e-04 -7.284409e-04 -7.650758e-04 ......
## ASV1409      1.128394e-03  1.182139e-03  1.238430e-03  1.297385e-03 ......
## ASV0770      3.205804e-04  3.333495e-04  3.465100e-04  3.600626e-04 ......
## ASV1403     -3.034969e-03 -3.171000e-03 -3.312762e-03 -3.460467e-03 ......
## ASV0314     -1.019307e-03 -1.062272e-03 -1.106774e-03 -1.152842e-03 ......
## ASV0187     -3.201187e-04 -3.351247e-04 -3.507955e-04 -3.671554e-04 ......
## ASV0313     -1.469153e-03 -1.532949e-03 -1.599238e-03 -1.668093e-03 ......
## ASV1087      3.455781e-03  3.611532e-03  3.773932e-03  3.943237e-03 ......
## ASV1970     -5.197454e-04 -5.426243e-04 -5.664148e-04 -5.911440e-04 ......
## ASV0754      3.830248e-03  4.004881e-03  4.187146e-03  4.377347e-03 ......
## ASV3775     -9.258987e-04 -9.689013e-04 -1.013852e-03 -1.060834e-03 ......
## ASV0132     -6.580997e-04 -6.879211e-04 -7.190294e-04 -7.514749e-04 ......
## ASV2329      1.657047e-04  1.599795e-04  1.530941e-04  1.449527e-04 ......
## ASV0561      9.084150e-04  9.444645e-04  9.815746e-04  1.019738e-03 ......
## ASV0130     -1.993142e-03 -2.083657e-03 -2.178071e-03 -2.276534e-03 ......
## ASV0226      2.484865e-03  2.595697e-03  2.711132e-03  2.831332e-03 ......
## ASV12648    -3.432867e-03 -3.583412e-03 -3.740175e-03 -3.903391e-03 ......
## ASV0204      2.391977e-03  2.498724e-03  2.609910e-03  2.725691e-03 ......
## ASV0767     -1.239370e-03 -1.301066e-03 -1.365934e-03 -1.434145e-03 ......
## ASV0335     -2.215780e-03 -2.313695e-03 -2.415581e-03 -2.521567e-03 ......
## ASV5901     -4.632939e-04 -4.825366e-04 -5.025117e-04 -5.232448e-04 ......
## ASV0596      5.111738e-05  5.734926e-05  6.419091e-05  7.169446e-05 ......
## ASV9271      1.988120e-03  2.089578e-03  2.196159e-03  2.308100e-03 ......
## ASV0904      1.489910e-03  1.560042e-03  1.633422e-03  1.710193e-03 ......
## ASV15270    -1.067079e-03 -1.122681e-03 -1.181109e-03 -1.242486e-03 ......
## ASV0990     -8.170211e-04 -8.550309e-04 -8.947679e-04 -9.363069e-04 ......
## ASV0155     -1.662541e-03 -1.737278e-03 -1.815172e-03 -1.896337e-03 ......
## ASV0086     -3.331152e-04 -3.482066e-04 -3.639470e-04 -3.803611e-04 ......
## ASV2581     -1.419566e-04 -1.468235e-04 -1.517437e-04 -1.567034e-04 ......
## ASV1579     -1.405130e-03 -1.471784e-03 -1.541566e-03 -1.614620e-03 ......
## ASV7730     -1.502770e-04 -1.611634e-04 -1.726709e-04 -1.848136e-04 ......
## ASV0897      2.171143e-04  2.278869e-04  2.392025e-04  2.510883e-04 ......
## ASV1975      9.338977e-03  9.762010e-03  1.020333e-02  1.066365e-02 ......
## 
##  .....suppressing 68 columns in show(); maybe adjust 'options(max.print= *, width = *)'
##  ..............................

stats:glm

1000

library(stats)

logreg_1000 <- stats::glm(as.factor(Clade) ~ . ,
                          data = lr_clr_df_1000[,-1],
                          family = "binomial")
summary(logreg_1000)
## 
## Call:
## stats::glm(formula = as.factor(Clade) ~ ., family = "binomial", 
##     data = lr_clr_df_1000[, -1])
## 
## Coefficients: (765 not defined because of singularities)
##               Estimate Std. Error    z value Pr(>|z|)    
## (Intercept) -1.288e+34  8.363e+18 -1.540e+15   <2e-16 ***
## ASV1236      1.024e+38  4.426e+22  2.314e+15   <2e-16 ***
## ASV0421      7.110e+37  1.895e+21  3.752e+16   <2e-16 ***
## ASV0691     -1.214e+39  1.057e+23 -1.148e+16   <2e-16 ***
## ASV0899      2.877e+37  2.571e+22  1.119e+15   <2e-16 ***
## ASV1004      3.517e+38  4.225e+22  8.324e+15   <2e-16 ***
## ASV1041      1.338e+38  3.947e+22  3.390e+15   <2e-16 ***
## ASV1058      2.498e+38  3.593e+22  6.952e+15   <2e-16 ***
## ASV12542    -4.340e+37  1.551e+23 -2.798e+14   <2e-16 ***
## ASV1294      2.494e+38  2.047e+22  1.218e+16   <2e-16 ***
## ASV13113     8.339e+36  5.073e+20  1.644e+16   <2e-16 ***
## ASV1318      2.471e+37  3.732e+21  6.619e+15   <2e-16 ***
## ASV2269      5.895e+39  3.584e+23  1.645e+16   <2e-16 ***
## ASV2542     -4.536e+37  3.407e+21 -1.331e+16   <2e-16 ***
## ASV2660     -4.874e+38  1.161e+23 -4.200e+15   <2e-16 ***
## ASV2737     -5.395e+38  1.727e+23 -3.125e+15   <2e-16 ***
## ASV2840      1.762e+37  1.291e+22  1.365e+15   <2e-16 ***
## ASV3053      2.135e+39  1.677e+24  1.273e+15   <2e-16 ***
## ASV3077     -6.557e+38  9.289e+22 -7.059e+15   <2e-16 ***
## ASV3134     -1.019e+37  7.464e+20 -1.366e+16   <2e-16 ***
## ASV3140     -2.041e+38  1.943e+22 -1.050e+16   <2e-16 ***
## ASV3579     -2.615e+36  1.838e+21 -1.423e+15   <2e-16 ***
## ASV6119             NA         NA         NA       NA    
## ASV7557             NA         NA         NA       NA    
## ASV8422             NA         NA         NA       NA    
## ASV1086             NA         NA         NA       NA    
## ASV1310     -2.838e+38  1.477e+22 -1.922e+16   <2e-16 ***
## ASV15750     1.277e+38  4.382e+22  2.914e+15   <2e-16 ***
## ASV16905            NA         NA         NA       NA    
## ASV2033      2.173e+38  8.651e+21  2.512e+16   <2e-16 ***
## ASV2089             NA         NA         NA       NA    
## ASV2127      1.934e+37  1.415e+22  1.367e+15   <2e-16 ***
## ASV2725     -4.149e+37  2.119e+22 -1.958e+15   <2e-16 ***
## ASV2804             NA         NA         NA       NA    
## ASV3075     -1.411e+38  6.252e+21 -2.256e+16   <2e-16 ***
## ASV3327      3.796e+37  1.624e+22  2.338e+15   <2e-16 ***
## ASV3342      8.216e+37  4.341e+21  1.893e+16   <2e-16 ***
## ASV3532      1.945e+38  2.131e+22  9.129e+15   <2e-16 ***
## ASV3600     -2.793e+37  9.223e+21 -3.028e+15   <2e-16 ***
## ASV4013     -4.767e+38  1.679e+23 -2.839e+15   <2e-16 ***
## ASV4136      1.909e+36  6.303e+22  3.029e+13   <2e-16 ***
## ASV4195             NA         NA         NA       NA    
## ASV4407             NA         NA         NA       NA    
## ASV4717             NA         NA         NA       NA    
## ASV6794             NA         NA         NA       NA    
## ASV8324             NA         NA         NA       NA    
## ASV8981      6.958e+37  3.856e+21  1.805e+16   <2e-16 ***
## ASV9859     -5.776e+37  4.555e+21 -1.268e+16   <2e-16 ***
## ASV0936     -2.450e+38  1.675e+22 -1.463e+16   <2e-16 ***
## ASV12683            NA         NA         NA       NA    
## ASV1293      3.468e+37  6.409e+21  5.412e+15   <2e-16 ***
## ASV13055            NA         NA         NA       NA    
## ASV17063            NA         NA         NA       NA    
## ASV2228             NA         NA         NA       NA    
## ASV2769      1.648e+37  1.082e+23  1.523e+14   <2e-16 ***
## ASV2803     -6.102e+38  2.216e+22 -2.753e+16   <2e-16 ***
## ASV2896     -1.307e+36  6.667e+20 -1.960e+15   <2e-16 ***
## ASV3062             NA         NA         NA       NA    
## ASV3107      4.930e+36  6.459e+20  7.632e+15   <2e-16 ***
## ASV3265      2.195e+38  2.259e+22  9.714e+15   <2e-16 ***
## ASV3666             NA         NA         NA       NA    
## ASV4497      7.858e+38  7.320e+22  1.073e+16   <2e-16 ***
## ASV6914             NA         NA         NA       NA    
## ASV0576      1.416e+38  1.171e+22  1.209e+16   <2e-16 ***
## ASV0673      6.569e+37  3.161e+22  2.078e+15   <2e-16 ***
## ASV0772     -9.348e+37  2.127e+22 -4.395e+15   <2e-16 ***
## ASV0862      9.086e+38  6.182e+22  1.470e+16   <2e-16 ***
## ASV0898             NA         NA         NA       NA    
## ASV0910     -8.264e+36  1.216e+21 -6.798e+15   <2e-16 ***
## ASV0964             NA         NA         NA       NA    
## ASV10059    -2.008e+37  9.305e+20 -2.158e+16   <2e-16 ***
## ASV10263            NA         NA         NA       NA    
## ASV1088     -1.309e+38  5.357e+21 -2.443e+16   <2e-16 ***
## ASV1101             NA         NA         NA       NA    
## ASV1183     -4.149e+37  2.163e+21 -1.919e+16   <2e-16 ***
## ASV11956            NA         NA         NA       NA    
## ASV12774            NA         NA         NA       NA    
## ASV1321             NA         NA         NA       NA    
## ASV13793            NA         NA         NA       NA    
## ASV14482            NA         NA         NA       NA    
## ASV15483            NA         NA         NA       NA    
## ASV2062             NA         NA         NA       NA    
## ASV2132      1.803e+36  5.881e+20  3.065e+15   <2e-16 ***
## ASV2413             NA         NA         NA       NA    
## ASV2490             NA         NA         NA       NA    
## ASV2594      3.563e+37  1.596e+21  2.232e+16   <2e-16 ***
## ASV2822             NA         NA         NA       NA    
## ASV2863             NA         NA         NA       NA    
## ASV2910             NA         NA         NA       NA    
## ASV2980     -9.393e+38  6.143e+22 -1.529e+16   <2e-16 ***
## ASV3307             NA         NA         NA       NA    
## ASV3474             NA         NA         NA       NA    
## ASV3502      6.558e+37  5.077e+21  1.292e+16   <2e-16 ***
## ASV4236             NA         NA         NA       NA    
## ASV4842             NA         NA         NA       NA    
## ASV4894             NA         NA         NA       NA    
## ASV5290             NA         NA         NA       NA    
## ASV5501     -1.991e+38  4.168e+22 -4.777e+15   <2e-16 ***
## ASV5795             NA         NA         NA       NA    
## ASV5987             NA         NA         NA       NA    
## ASV6267             NA         NA         NA       NA    
## ASV6862             NA         NA         NA       NA    
## ASV7145             NA         NA         NA       NA    
## ASV7673             NA         NA         NA       NA    
## ASV7789             NA         NA         NA       NA    
## ASV7809             NA         NA         NA       NA    
## ASV8002             NA         NA         NA       NA    
## ASV8205      5.085e+37  2.745e+21  1.853e+16   <2e-16 ***
## ASV9155             NA         NA         NA       NA    
## ASV9221     -5.699e+37  5.216e+21 -1.093e+16   <2e-16 ***
## ASV9311             NA         NA         NA       NA    
## ASV9557             NA         NA         NA       NA    
## ASV9936             NA         NA         NA       NA    
## ASV1445     -3.061e+37  1.052e+22 -2.910e+15   <2e-16 ***
## ASV4232      3.577e+36  4.082e+20  8.763e+15   <2e-16 ***
## ASV6479     -2.869e+37  1.937e+21 -1.481e+16   <2e-16 ***
## ASV0142      1.095e+38  1.157e+22  9.463e+15   <2e-16 ***
## ASV0378     -1.451e+38  7.674e+21 -1.891e+16   <2e-16 ***
## ASV1122     -3.809e+37  1.168e+22 -3.260e+15   <2e-16 ***
## ASV0123      3.023e+37  1.271e+22  2.379e+15   <2e-16 ***
## ASV2064      2.134e+38  1.434e+22  1.488e+16   <2e-16 ***
## ASV4459     -1.091e+38  5.030e+21 -2.170e+16   <2e-16 ***
## ASV0448      5.514e+36  4.265e+20  1.293e+16   <2e-16 ***
## ASV0397      2.975e+37  7.627e+20  3.901e+16   <2e-16 ***
## ASV0485      2.182e+37  1.937e+21  1.126e+16   <2e-16 ***
## ASV1566             NA         NA         NA       NA    
## ASV1365     -1.280e+38  8.600e+21 -1.489e+16   <2e-16 ***
## ASV1065      9.217e+37  7.106e+21  1.297e+16   <2e-16 ***
## ASV0722      5.134e+36  3.956e+21  1.298e+15   <2e-16 ***
## ASV12660            NA         NA         NA       NA    
## ASV0223      8.402e+36  4.058e+20  2.071e+16   <2e-16 ***
## ASV0229      4.373e+37  9.283e+21  4.711e+15   <2e-16 ***
## ASV0877     -8.335e+36  4.455e+21 -1.871e+15   <2e-16 ***
## ASV0983     -7.332e+37  4.541e+21 -1.615e+16   <2e-16 ***
## ASV0626             NA         NA         NA       NA    
## ASV4146     -9.667e+37  7.302e+21 -1.324e+16   <2e-16 ***
## ASV4175      2.547e+37  7.547e+21  3.375e+15   <2e-16 ***
## ASV2082      1.194e+38  1.287e+22  9.275e+15   <2e-16 ***
## ASV2272     -4.011e+36  9.680e+20 -4.143e+15   <2e-16 ***
## ASV2245     -8.718e+37  7.061e+21 -1.235e+16   <2e-16 ***
## ASV0590             NA         NA         NA       NA    
## ASV0217      1.332e+37  5.036e+20  2.644e+16   <2e-16 ***
## ASV0416      9.422e+37  4.921e+21  1.915e+16   <2e-16 ***
## ASV1056     -6.089e+36  1.899e+21 -3.206e+15   <2e-16 ***
## ASV7777     -2.828e+35  3.524e+19 -8.027e+15   <2e-16 ***
## ASV0455      1.360e+37  9.123e+20  1.491e+16   <2e-16 ***
## ASV0604             NA         NA         NA       NA    
## ASV6100      2.054e+36  2.570e+20  7.994e+15   <2e-16 ***
## ASV11359            NA         NA         NA       NA    
## ASV6604     -1.088e+37  6.176e+20 -1.762e+16   <2e-16 ***
## ASV5004     -2.397e+37  5.634e+21 -4.255e+15   <2e-16 ***
## ASV1483      2.367e+37  4.211e+21  5.621e+15   <2e-16 ***
## ASV9773     -3.750e+34  2.983e+18 -1.257e+16   <2e-16 ***
## ASV4059      2.837e+37  3.643e+21  7.787e+15   <2e-16 ***
## ASV1193      2.533e+37  1.265e+21  2.003e+16   <2e-16 ***
## ASV4610             NA         NA         NA       NA    
## ASV0742             NA         NA         NA       NA    
## ASV1502     -7.507e+37  5.530e+21 -1.357e+16   <2e-16 ***
## ASV0195      1.767e+37  1.937e+21  9.122e+15   <2e-16 ***
## ASV1213     -5.878e+37  5.089e+21 -1.155e+16   <2e-16 ***
## ASV1648     -7.475e+36  2.926e+21 -2.555e+15   <2e-16 ***
## ASV6984     -4.045e+37  1.520e+21 -2.661e+16   <2e-16 ***
## ASV0396      1.781e+35  7.231e+20  2.463e+14   <2e-16 ***
## ASV4297             NA         NA         NA       NA    
## ASV2622     -2.489e+37  1.719e+21 -1.448e+16   <2e-16 ***
## ASV3512     -2.045e+36  4.062e+20 -5.036e+15   <2e-16 ***
## ASV2411             NA         NA         NA       NA    
## ASV2291             NA         NA         NA       NA    
## ASV0807     -2.261e+37  1.502e+21 -1.505e+16   <2e-16 ***
## ASV1292     -1.988e+37  1.213e+21 -1.639e+16   <2e-16 ***
## ASV1035             NA         NA         NA       NA    
## ASV0070      1.059e+35  1.539e+19  6.882e+15   <2e-16 ***
## ASV0255      4.556e+36  3.898e+20  1.169e+16   <2e-16 ***
## ASV0057      4.126e+36  2.372e+20  1.739e+16   <2e-16 ***
## ASV0077     -5.617e+35  1.191e+20 -4.716e+15   <2e-16 ***
## ASV0625      3.369e+37  1.629e+21  2.068e+16   <2e-16 ***
## ASV2464             NA         NA         NA       NA    
## ASV1315     -1.959e+37  1.566e+21 -1.251e+16   <2e-16 ***
## ASV2673     -6.098e+36  5.105e+20 -1.195e+16   <2e-16 ***
## ASV2161      2.883e+37  1.812e+21  1.591e+16   <2e-16 ***
## ASV0337     -5.602e+36  3.933e+20 -1.424e+16   <2e-16 ***
## ASV7680     -5.037e+37  2.606e+21 -1.933e+16   <2e-16 ***
## ASV0611     -4.503e+36  4.314e+20 -1.044e+16   <2e-16 ***
## ASV3118     -1.223e+38  1.074e+22 -1.138e+16   <2e-16 ***
## ASV1284      3.351e+36  2.997e+20  1.118e+16   <2e-16 ***
## ASV0889             NA         NA         NA       NA    
## ASV4649     -4.528e+37  2.587e+21 -1.750e+16   <2e-16 ***
## ASV1108      7.837e+36  2.367e+21  3.311e+15   <2e-16 ***
## ASV0738     -7.993e+36  5.564e+20 -1.436e+16   <2e-16 ***
## ASV0473      1.898e+36  1.918e+20  9.896e+15   <2e-16 ***
## ASV0598             NA         NA         NA       NA    
## ASV0429     -3.054e+37  2.478e+21 -1.233e+16   <2e-16 ***
## ASV1549     -1.529e+36  2.122e+20 -7.204e+15   <2e-16 ***
## ASV1203     -1.640e+37  1.353e+21 -1.212e+16   <2e-16 ***
## ASV4532      6.531e+36  4.831e+20  1.352e+16   <2e-16 ***
## ASV0274      1.609e+37  6.816e+20  2.360e+16   <2e-16 ***
## ASV0163      1.761e+37  1.836e+21  9.591e+15   <2e-16 ***
## ASV1298      1.728e+35  8.059e+20  2.145e+14   <2e-16 ***
## ASV9424      7.313e+37  4.239e+21  1.725e+16   <2e-16 ***
## ASV0412     -6.623e+37  8.254e+21 -8.024e+15   <2e-16 ***
## ASV0284      3.522e+37  1.627e+21  2.164e+16   <2e-16 ***
## ASV0620             NA         NA         NA       NA    
## ASV0153     -3.630e+36  4.115e+20 -8.822e+15   <2e-16 ***
## ASV0498     -1.296e+37  1.091e+21 -1.189e+16   <2e-16 ***
## ASV0097      2.914e+36  4.176e+20  6.976e+15   <2e-16 ***
## ASV0104     -9.662e+36  6.073e+20 -1.591e+16   <2e-16 ***
## ASV1282      5.958e+37  3.199e+21  1.862e+16   <2e-16 ***
## ASV3883     -2.974e+37  1.546e+21 -1.924e+16   <2e-16 ***
## ASV0801      7.240e+37  4.005e+21  1.808e+16   <2e-16 ***
## ASV1611     -4.028e+37  2.238e+21 -1.800e+16   <2e-16 ***
## ASV0227     -1.018e+37  7.162e+20 -1.422e+16   <2e-16 ***
## ASV0833             NA         NA         NA       NA    
## ASV0718     -2.274e+37  6.617e+20 -3.437e+16   <2e-16 ***
## ASV1139             NA         NA         NA       NA    
## ASV0766      1.680e+37  3.541e+21  4.745e+15   <2e-16 ***
## ASV2091      2.604e+37  1.827e+21  1.425e+16   <2e-16 ***
## ASV1238      5.942e+37  4.569e+21  1.301e+16   <2e-16 ***
## ASV9193             NA         NA         NA       NA    
## ASV0290      3.269e+37  1.295e+21  2.524e+16   <2e-16 ***
## ASV0231     -1.859e+37  1.643e+21 -1.131e+16   <2e-16 ***
## ASV0185     -9.323e+35  1.175e+20 -7.938e+15   <2e-16 ***
## ASV2330             NA         NA         NA       NA    
## ASV3119     -1.786e+35  6.412e+19 -2.786e+15   <2e-16 ***
## ASV2368      1.453e+36  2.313e+20  6.284e+15   <2e-16 ***
## ASV0122     -2.332e+36  2.666e+20 -8.749e+15   <2e-16 ***
## ASV1044      2.267e+36  4.767e+20  4.755e+15   <2e-16 ***
## ASV0160     -1.036e+36  1.387e+20 -7.467e+15   <2e-16 ***
## ASV0326     -4.935e+34  8.651e+18 -5.705e+15   <2e-16 ***
## ASV1388      1.098e+37  5.467e+20  2.008e+16   <2e-16 ***
## ASV0792             NA         NA         NA       NA    
## ASV0036      2.466e+36  2.958e+20  8.337e+15   <2e-16 ***
## ASV2125     -3.381e+37  2.364e+20 -1.430e+17   <2e-16 ***
## ASV1075      3.328e+35  5.454e+19  6.103e+15   <2e-16 ***
## ASV0390      1.123e+36  1.404e+20  7.997e+15   <2e-16 ***
## ASV3790     -2.602e+35  1.913e+20 -1.360e+15   <2e-16 ***
## ASV1535      4.452e+36  5.559e+20  8.009e+15   <2e-16 ***
## ASV0263             NA         NA         NA       NA    
## ASV0675      1.084e+36  1.176e+20  9.213e+15   <2e-16 ***
## ASV3348     -3.341e+35  3.274e+20 -1.021e+15   <2e-16 ***
## ASV0058     -8.929e+35  9.675e+19 -9.228e+15   <2e-16 ***
## ASV4142             NA         NA         NA       NA    
## ASV0059      8.725e+35  8.087e+19  1.079e+16   <2e-16 ***
## ASV0013     -1.483e+36  1.227e+20 -1.209e+16   <2e-16 ***
## ASV0033      1.438e+36  5.005e+20  2.873e+15   <2e-16 ***
## ASV4354             NA         NA         NA       NA    
## ASV0022     -2.846e+36  1.822e+20 -1.562e+16   <2e-16 ***
## ASV0134     -2.484e+37  9.924e+20 -2.503e+16   <2e-16 ***
## ASV0415      3.102e+37  1.030e+21  3.013e+16   <2e-16 ***
## ASV10103            NA         NA         NA       NA    
## ASV1613     -9.886e+36  1.415e+21 -6.988e+15   <2e-16 ***
## ASV0135     -3.503e+35  4.439e+19 -7.893e+15   <2e-16 ***
## ASV0469             NA         NA         NA       NA    
## ASV0471     -1.199e+37  1.023e+21 -1.172e+16   <2e-16 ***
## ASV0451      6.160e+35  8.455e+19  7.286e+15   <2e-16 ***
## ASV0747      9.397e+36  7.406e+20  1.269e+16   <2e-16 ***
## ASV1314     -2.326e+35  2.861e+19 -8.129e+15   <2e-16 ***
## ASV0425             NA         NA         NA       NA    
## ASV0559      4.886e+37  1.982e+21  2.465e+16   <2e-16 ***
## ASV0148      8.356e+34  1.598e+19  5.228e+15   <2e-16 ***
## ASV0129      5.785e+35  4.789e+19  1.208e+16   <2e-16 ***
## ASV1072      1.438e+36  1.612e+20  8.924e+15   <2e-16 ***
## ASV2390             NA         NA         NA       NA    
## ASV0548      8.543e+36  7.800e+20  1.095e+16   <2e-16 ***
## ASV0168      8.974e+34  1.148e+19  7.819e+15   <2e-16 ***
## ASV0066      1.351e+33  8.744e+17  1.545e+15   <2e-16 ***
## ASV0468     -8.917e+33  5.606e+18 -1.591e+15   <2e-16 ***
## ASV0172      1.147e+36  9.969e+19  1.151e+16   <2e-16 ***
## ASV0236      2.468e+37  4.424e+20  5.578e+16   <2e-16 ***
## ASV0250      1.872e+35  2.488e+19  7.527e+15   <2e-16 ***
## ASV0338     -4.599e+36  4.192e+20 -1.097e+16   <2e-16 ***
## ASV0450     -2.960e+35  4.399e+19 -6.730e+15   <2e-16 ***
## ASV0377             NA         NA         NA       NA    
## ASV1022      1.599e+35  1.427e+19  1.120e+16   <2e-16 ***
## ASV6174             NA         NA         NA       NA    
## ASV0786             NA         NA         NA       NA    
## ASV0053     -5.722e+35  7.946e+19 -7.200e+15   <2e-16 ***
## ASV0697     -1.742e+36  1.421e+20 -1.226e+16   <2e-16 ***
## ASV0785     -7.239e+35  9.908e+19 -7.307e+15   <2e-16 ***
## ASV1967     -1.044e+35  1.347e+19 -7.748e+15   <2e-16 ***
## ASV0385     -3.900e+36  5.089e+20 -7.662e+15   <2e-16 ***
## ASV0295     -1.183e+35  1.142e+19 -1.036e+16   <2e-16 ***
## ASV0072     -1.392e+35  1.934e+19 -7.198e+15   <2e-16 ***
## ASV0157      1.076e+36  1.069e+20  1.006e+16   <2e-16 ***
## ASV0501      6.524e+36  5.663e+20  1.152e+16   <2e-16 ***
## ASV10729     7.784e+36  4.460e+20  1.745e+16   <2e-16 ***
## ASV1470             NA         NA         NA       NA    
## ASV0050      1.041e+37  4.694e+20  2.218e+16   <2e-16 ***
## ASV0411     -1.631e+35  2.094e+19 -7.790e+15   <2e-16 ***
## ASV0549     -3.438e+36  4.081e+20 -8.426e+15   <2e-16 ***
## ASV0184      1.117e+34  6.522e+18  1.713e+15   <2e-16 ***
## ASV0705      9.729e+35  1.192e+20  8.162e+15   <2e-16 ***
## ASV1715      3.131e+36  4.839e+20  6.469e+15   <2e-16 ***
## ASV0603      5.862e+34  1.673e+19  3.503e+15   <2e-16 ***
## ASV0826     -2.826e+37  8.451e+20 -3.344e+16   <2e-16 ***
## ASV0034      1.855e+35  2.101e+19  8.827e+15   <2e-16 ***
## ASV0838      1.286e+37  1.051e+21  1.224e+16   <2e-16 ***
## ASV0614     -1.232e+36  1.062e+20 -1.160e+16   <2e-16 ***
## ASV0014     -1.937e+36  5.937e+20 -3.262e+15   <2e-16 ***
## ASV0585             NA         NA         NA       NA    
## ASV0016      1.934e+36  7.272e+20  2.660e+15   <2e-16 ***
## ASV5394      3.265e+35  1.180e+20  2.767e+15   <2e-16 ***
## ASV0666             NA         NA         NA       NA    
## ASV2085             NA         NA         NA       NA    
## ASV0003      1.679e+36  2.203e+20  7.623e+15   <2e-16 ***
## ASV0346      2.786e+36  5.059e+20  5.506e+15   <2e-16 ***
## ASV0267     -5.355e+36  5.906e+20 -9.068e+15   <2e-16 ***
## ASV0353     -1.281e+36  1.280e+20 -1.001e+16   <2e-16 ***
## ASV2419      1.590e+37  1.395e+21  1.139e+16   <2e-16 ***
## ASV0447             NA         NA         NA       NA    
## ASV0654             NA         NA         NA       NA    
## ASV0151      1.600e+36  2.598e+20  6.159e+15   <2e-16 ***
## ASV0065      2.256e+35  3.067e+19  7.356e+15   <2e-16 ***
## ASV0527      3.114e+36  9.700e+19  3.210e+16   <2e-16 ***
## ASV4055             NA         NA         NA       NA    
## ASV0166             NA         NA         NA       NA    
## ASV0417      4.866e+35  5.229e+19  9.306e+15   <2e-16 ***
## ASV0078     -5.905e+33  3.820e+18 -1.546e+15   <2e-16 ***
## ASV0322             NA         NA         NA       NA    
## ASV0156     -4.705e+34  1.548e+19 -3.040e+15   <2e-16 ***
## ASV0648             NA         NA         NA       NA    
## ASV0407     -7.655e+34  1.024e+19 -7.477e+15   <2e-16 ***
## ASV2030             NA         NA         NA       NA    
## ASV0300      3.354e+33  3.515e+18  9.541e+14   <2e-16 ***
## ASV1150     -2.182e+35  3.140e+19 -6.949e+15   <2e-16 ***
## ASV0958     -2.016e+37  6.862e+19 -2.938e+17   <2e-16 ***
## ASV0216             NA         NA         NA       NA    
## ASV0446      6.844e+34  8.616e+19  7.944e+14   <2e-16 ***
## ASV0367             NA         NA         NA       NA    
## ASV0200             NA         NA         NA       NA    
## ASV0334             NA         NA         NA       NA    
## ASV1311             NA         NA         NA       NA    
## ASV0458             NA         NA         NA       NA    
## ASV1371             NA         NA         NA       NA    
## ASV0418             NA         NA         NA       NA    
## ASV0004      4.799e+33  3.094e+18  1.551e+15   <2e-16 ***
## ASV1943             NA         NA         NA       NA    
## ASV1495             NA         NA         NA       NA    
## ASV0901             NA         NA         NA       NA    
## ASV0628             NA         NA         NA       NA    
## ASV0400             NA         NA         NA       NA    
## ASV0116             NA         NA         NA       NA    
## ASV0788             NA         NA         NA       NA    
## ASV0117             NA         NA         NA       NA    
## ASV3137             NA         NA         NA       NA    
## ASV0001             NA         NA         NA       NA    
## ASV1651             NA         NA         NA       NA    
## ASV1692             NA         NA         NA       NA    
## ASV0660             NA         NA         NA       NA    
## ASV0508             NA         NA         NA       NA    
## ASV1660             NA         NA         NA       NA    
## ASV0233             NA         NA         NA       NA    
## ASV1343             NA         NA         NA       NA    
## ASV0209             NA         NA         NA       NA    
## ASV0193             NA         NA         NA       NA    
## ASV0357             NA         NA         NA       NA    
## ASV0198             NA         NA         NA       NA    
## ASV0007             NA         NA         NA       NA    
## ASV1772             NA         NA         NA       NA    
## ASV0009             NA         NA         NA       NA    
## ASV0006             NA         NA         NA       NA    
## ASV0011             NA         NA         NA       NA    
## ASV0015             NA         NA         NA       NA    
## ASV0017             NA         NA         NA       NA    
## ASV0235             NA         NA         NA       NA    
## ASV0382             NA         NA         NA       NA    
## ASV2357             NA         NA         NA       NA    
## ASV0567             NA         NA         NA       NA    
## ASV0165             NA         NA         NA       NA    
## ASV0005             NA         NA         NA       NA    
## ASV0384             NA         NA         NA       NA    
## ASV0002             NA         NA         NA       NA    
## ASV3017             NA         NA         NA       NA    
## ASV0091             NA         NA         NA       NA    
## ASV0186             NA         NA         NA       NA    
## ASV0370             NA         NA         NA       NA    
## ASV0018             NA         NA         NA       NA    
## ASV1377             NA         NA         NA       NA    
## ASV0019             NA         NA         NA       NA    
## ASV0023             NA         NA         NA       NA    
## ASV2194             NA         NA         NA       NA    
## ASV1155             NA         NA         NA       NA    
## ASV0510             NA         NA         NA       NA    
## ASV2371             NA         NA         NA       NA    
## ASV0024             NA         NA         NA       NA    
## ASV2452             NA         NA         NA       NA    
## ASV2332             NA         NA         NA       NA    
## ASV2591             NA         NA         NA       NA    
## ASV0521             NA         NA         NA       NA    
## ASV5542             NA         NA         NA       NA    
## ASV0336             NA         NA         NA       NA    
## ASV10102            NA         NA         NA       NA    
## ASV16823            NA         NA         NA       NA    
## ASV3104             NA         NA         NA       NA    
## ASV0781             NA         NA         NA       NA    
## ASV10899            NA         NA         NA       NA    
## ASV11222            NA         NA         NA       NA    
## ASV11327            NA         NA         NA       NA    
## ASV12458            NA         NA         NA       NA    
## ASV1636             NA         NA         NA       NA    
## ASV1890             NA         NA         NA       NA    
## ASV2898             NA         NA         NA       NA    
## ASV8328             NA         NA         NA       NA    
## ASV0709             NA         NA         NA       NA    
## ASV0856             NA         NA         NA       NA    
## ASV0909             NA         NA         NA       NA    
## ASV0937             NA         NA         NA       NA    
## ASV11390            NA         NA         NA       NA    
## ASV11966            NA         NA         NA       NA    
## ASV12990            NA         NA         NA       NA    
## ASV14797            NA         NA         NA       NA    
## ASV14904            NA         NA         NA       NA    
## ASV15304            NA         NA         NA       NA    
## ASV16696            NA         NA         NA       NA    
## ASV1690             NA         NA         NA       NA    
## ASV2029             NA         NA         NA       NA    
## ASV2834             NA         NA         NA       NA    
## ASV4003             NA         NA         NA       NA    
## ASV4064             NA         NA         NA       NA    
## ASV4294             NA         NA         NA       NA    
## ASV4609             NA         NA         NA       NA    
## ASV6283             NA         NA         NA       NA    
## ASV6491             NA         NA         NA       NA    
## ASV7453             NA         NA         NA       NA    
## ASV7959             NA         NA         NA       NA    
## ASV8219             NA         NA         NA       NA    
## ASV8547             NA         NA         NA       NA    
## ASV9319             NA         NA         NA       NA    
## ASV9382             NA         NA         NA       NA    
## ASV11516            NA         NA         NA       NA    
## ASV14377            NA         NA         NA       NA    
## ASV1867             NA         NA         NA       NA    
## ASV1895             NA         NA         NA       NA    
## ASV3168             NA         NA         NA       NA    
## ASV4449             NA         NA         NA       NA    
## ASV6596             NA         NA         NA       NA    
## ASV7492             NA         NA         NA       NA    
## ASV9854             NA         NA         NA       NA    
## ASV6296             NA         NA         NA       NA    
## ASV4201             NA         NA         NA       NA    
## ASV0552             NA         NA         NA       NA    
## ASV3671             NA         NA         NA       NA    
## ASV3529             NA         NA         NA       NA    
## ASV1060             NA         NA         NA       NA    
## ASV0239             NA         NA         NA       NA    
## ASV5711             NA         NA         NA       NA    
## ASV4152             NA         NA         NA       NA    
## ASV1461             NA         NA         NA       NA    
## ASV2877             NA         NA         NA       NA    
## ASV0012             NA         NA         NA       NA    
## ASV9823             NA         NA         NA       NA    
## ASV0008             NA         NA         NA       NA    
## ASV7832             NA         NA         NA       NA    
## ASV1915             NA         NA         NA       NA    
## ASV0055             NA         NA         NA       NA    
## ASV0032             NA         NA         NA       NA    
## ASV2977             NA         NA         NA       NA    
## ASV0466             NA         NA         NA       NA    
## ASV3866             NA         NA         NA       NA    
## ASV0040             NA         NA         NA       NA    
## ASV0496             NA         NA         NA       NA    
## ASV0052             NA         NA         NA       NA    
## ASV3828      6.303e+33  5.110e+18  1.233e+15   <2e-16 ***
## ASV1930             NA         NA         NA       NA    
## ASV2126             NA         NA         NA       NA    
## ASV0793             NA         NA         NA       NA    
## ASV0299             NA         NA         NA       NA    
## ASV0208             NA         NA         NA       NA    
## ASV0511             NA         NA         NA       NA    
## ASV1123             NA         NA         NA       NA    
## ASV0099             NA         NA         NA       NA    
## ASV0752             NA         NA         NA       NA    
## ASV0883             NA         NA         NA       NA    
## ASV0683      1.498e+37  1.117e+21  1.341e+16   <2e-16 ***
## ASV4117             NA         NA         NA       NA    
## ASV2172             NA         NA         NA       NA    
## ASV0330             NA         NA         NA       NA    
## ASV0728             NA         NA         NA       NA    
## ASV0499             NA         NA         NA       NA    
## ASV0120             NA         NA         NA       NA    
## ASV1446             NA         NA         NA       NA    
## ASV17171            NA         NA         NA       NA    
## ASV0533             NA         NA         NA       NA    
## ASV2495             NA         NA         NA       NA    
## ASV5582             NA         NA         NA       NA    
## ASV1488             NA         NA         NA       NA    
## ASV0682             NA         NA         NA       NA    
## ASV0068             NA         NA         NA       NA    
## ASV1987             NA         NA         NA       NA    
## ASV0035             NA         NA         NA       NA    
## ASV7192             NA         NA         NA       NA    
## ASV0873             NA         NA         NA       NA    
## ASV4749             NA         NA         NA       NA    
## ASV2174             NA         NA         NA       NA    
## ASV1476             NA         NA         NA       NA    
## ASV0740             NA         NA         NA       NA    
## ASV0170             NA         NA         NA       NA    
## ASV2466             NA         NA         NA       NA    
## ASV1709             NA         NA         NA       NA    
## ASV6170             NA         NA         NA       NA    
## ASV3673             NA         NA         NA       NA    
## ASV1745             NA         NA         NA       NA    
## ASV0380             NA         NA         NA       NA    
## ASV0426             NA         NA         NA       NA    
## ASV0202             NA         NA         NA       NA    
## ASV6350             NA         NA         NA       NA    
## ASV0713             NA         NA         NA       NA    
## ASV1822             NA         NA         NA       NA    
## ASV4569             NA         NA         NA       NA    
## ASV0030             NA         NA         NA       NA    
## ASV0331             NA         NA         NA       NA    
## ASV2981             NA         NA         NA       NA    
## ASV0828             NA         NA         NA       NA    
## ASV2440             NA         NA         NA       NA    
## ASV3006             NA         NA         NA       NA    
## ASV3875             NA         NA         NA       NA    
## ASV4511             NA         NA         NA       NA    
## ASV4700             NA         NA         NA       NA    
## ASV5804             NA         NA         NA       NA    
## ASV6826             NA         NA         NA       NA    
## ASV7280             NA         NA         NA       NA    
## ASV7535             NA         NA         NA       NA    
## ASV0651             NA         NA         NA       NA    
## ASV0913             NA         NA         NA       NA    
## ASV10832            NA         NA         NA       NA    
## ASV1117             NA         NA         NA       NA    
## ASV11329            NA         NA         NA       NA    
## ASV13209            NA         NA         NA       NA    
## ASV1345             NA         NA         NA       NA    
## ASV1719             NA         NA         NA       NA    
## ASV1886             NA         NA         NA       NA    
## ASV2158             NA         NA         NA       NA    
## ASV2189             NA         NA         NA       NA    
## ASV2257             NA         NA         NA       NA    
## ASV2283             NA         NA         NA       NA    
## ASV2328             NA         NA         NA       NA    
## ASV2434             NA         NA         NA       NA    
## ASV2648             NA         NA         NA       NA    
## ASV2698             NA         NA         NA       NA    
## ASV2775             NA         NA         NA       NA    
## ASV3171             NA         NA         NA       NA    
## ASV3227             NA         NA         NA       NA    
## ASV3397             NA         NA         NA       NA    
## ASV3444             NA         NA         NA       NA    
## ASV3556             NA         NA         NA       NA    
## ASV3606             NA         NA         NA       NA    
## ASV4190             NA         NA         NA       NA    
## ASV4197             NA         NA         NA       NA    
## ASV4722             NA         NA         NA       NA    
## ASV4765             NA         NA         NA       NA    
## ASV4809             NA         NA         NA       NA    
## ASV4846             NA         NA         NA       NA    
## ASV4903             NA         NA         NA       NA    
## ASV4944             NA         NA         NA       NA    
## ASV5151             NA         NA         NA       NA    
## ASV5413             NA         NA         NA       NA    
## ASV5537             NA         NA         NA       NA    
## ASV5688             NA         NA         NA       NA    
## ASV5752             NA         NA         NA       NA    
## ASV6122             NA         NA         NA       NA    
## ASV6135             NA         NA         NA       NA    
## ASV6188             NA         NA         NA       NA    
## ASV6216             NA         NA         NA       NA    
## ASV6242             NA         NA         NA       NA    
## ASV6383             NA         NA         NA       NA    
## ASV6781             NA         NA         NA       NA    
## ASV6799             NA         NA         NA       NA    
## ASV7374             NA         NA         NA       NA    
## ASV7539             NA         NA         NA       NA    
## ASV8591             NA         NA         NA       NA    
## ASV8637             NA         NA         NA       NA    
## ASV12796            NA         NA         NA       NA    
## ASV1934             NA         NA         NA       NA    
## ASV22549            NA         NA         NA       NA    
## ASV29857            NA         NA         NA       NA    
## ASV3215             NA         NA         NA       NA    
## ASV3236             NA         NA         NA       NA    
## ASV3954             NA         NA         NA       NA    
## ASV4850             NA         NA         NA       NA    
## ASV5225             NA         NA         NA       NA    
## ASV5532             NA         NA         NA       NA    
## ASV7258             NA         NA         NA       NA    
## ASV9474             NA         NA         NA       NA    
## ASV11857            NA         NA         NA       NA    
## ASV1202             NA         NA         NA       NA    
## ASV14742            NA         NA         NA       NA    
## ASV16652            NA         NA         NA       NA    
## ASV2019             NA         NA         NA       NA    
## ASV2410             NA         NA         NA       NA    
## ASV2718             NA         NA         NA       NA    
## ASV2738             NA         NA         NA       NA    
## ASV2876             NA         NA         NA       NA    
## ASV3177             NA         NA         NA       NA    
## ASV4367             NA         NA         NA       NA    
## ASV4635             NA         NA         NA       NA    
## ASV4896             NA         NA         NA       NA    
## ASV4907             NA         NA         NA       NA    
## ASV5230             NA         NA         NA       NA    
## ASV6509             NA         NA         NA       NA    
## ASV7376             NA         NA         NA       NA    
## ASV8163             NA         NA         NA       NA    
## ASV8195             NA         NA         NA       NA    
## ASV8923             NA         NA         NA       NA    
## ASV9666             NA         NA         NA       NA    
## ASV1482             NA         NA         NA       NA    
## ASV2726             NA         NA         NA       NA    
## ASV3281             NA         NA         NA       NA    
## ASV4235             NA         NA         NA       NA    
## ASV4808             NA         NA         NA       NA    
## ASV4861             NA         NA         NA       NA    
## ASV5276             NA         NA         NA       NA    
## ASV5837             NA         NA         NA       NA    
## ASV7098             NA         NA         NA       NA    
## ASV8451             NA         NA         NA       NA    
## ASV8694             NA         NA         NA       NA    
## ASV0905             NA         NA         NA       NA    
## ASV2900             NA         NA         NA       NA    
## ASV3963             NA         NA         NA       NA    
## ASV0041             NA         NA         NA       NA    
## ASV1865             NA         NA         NA       NA    
## ASV1140             NA         NA         NA       NA    
## ASV1179             NA         NA         NA       NA    
## ASV0279             NA         NA         NA       NA    
## ASV0043             NA         NA         NA       NA    
## ASV2097             NA         NA         NA       NA    
## ASV0309             NA         NA         NA       NA    
## ASV0607             NA         NA         NA       NA    
## ASV0025             NA         NA         NA       NA    
## ASV2284             NA         NA         NA       NA    
## ASV0556             NA         NA         NA       NA    
## ASV5040             NA         NA         NA       NA    
## ASV2924             NA         NA         NA       NA    
## ASV1331             NA         NA         NA       NA    
## ASV0506             NA         NA         NA       NA    
## ASV1514             NA         NA         NA       NA    
## ASV2144             NA         NA         NA       NA    
## ASV2265             NA         NA         NA       NA    
## ASV5156             NA         NA         NA       NA    
## ASV5534             NA         NA         NA       NA    
## ASV5747             NA         NA         NA       NA    
## ASV6657             NA         NA         NA       NA    
## ASV0658             NA         NA         NA       NA    
## ASV0716             NA         NA         NA       NA    
## ASV1657             NA         NA         NA       NA    
## ASV1885             NA         NA         NA       NA    
## ASV2333             NA         NA         NA       NA    
## ASV3375             NA         NA         NA       NA    
## ASV4317             NA         NA         NA       NA    
## ASV9599             NA         NA         NA       NA    
## ASV0175             NA         NA         NA       NA    
## ASV1032             NA         NA         NA       NA    
## ASV1235             NA         NA         NA       NA    
## ASV1262             NA         NA         NA       NA    
## ASV1320             NA         NA         NA       NA    
## ASV13797            NA         NA         NA       NA    
## ASV1491             NA         NA         NA       NA    
## ASV15014            NA         NA         NA       NA    
## ASV1510             NA         NA         NA       NA    
## ASV1551             NA         NA         NA       NA    
## ASV1919             NA         NA         NA       NA    
## ASV2114      1.923e+37  1.314e+21  1.463e+16   <2e-16 ***
## ASV21486            NA         NA         NA       NA    
## ASV2448             NA         NA         NA       NA    
## ASV2589             NA         NA         NA       NA    
## ASV2608             NA         NA         NA       NA    
## ASV2786             NA         NA         NA       NA    
## ASV2827             NA         NA         NA       NA    
## ASV2872             NA         NA         NA       NA    
## ASV3125             NA         NA         NA       NA    
## ASV3247             NA         NA         NA       NA    
## ASV3451             NA         NA         NA       NA    
## ASV3465             NA         NA         NA       NA    
## ASV3809             NA         NA         NA       NA    
## ASV4006             NA         NA         NA       NA    
## ASV4046             NA         NA         NA       NA    
## ASV4938             NA         NA         NA       NA    
## ASV5435             NA         NA         NA       NA    
## ASV5605             NA         NA         NA       NA    
## ASV5635             NA         NA         NA       NA    
## ASV5743             NA         NA         NA       NA    
## ASV6627             NA         NA         NA       NA    
## ASV6785             NA         NA         NA       NA    
## ASV7368             NA         NA         NA       NA    
## ASV9118             NA         NA         NA       NA    
## ASV9135             NA         NA         NA       NA    
## ASV9435             NA         NA         NA       NA    
## ASV9671             NA         NA         NA       NA    
## ASV0387             NA         NA         NA       NA    
## ASV0454             NA         NA         NA       NA    
## ASV0751             NA         NA         NA       NA    
## ASV1081             NA         NA         NA       NA    
## ASV1332             NA         NA         NA       NA    
## ASV2659             NA         NA         NA       NA    
## ASV2979             NA         NA         NA       NA    
## ASV4184             NA         NA         NA       NA    
## ASV6198             NA         NA         NA       NA    
## ASV7454             NA         NA         NA       NA    
## ASV8198             NA         NA         NA       NA    
## ASV0855             NA         NA         NA       NA    
## ASV10092            NA         NA         NA       NA    
## ASV1532             NA         NA         NA       NA    
## ASV2553             NA         NA         NA       NA    
## ASV2741             NA         NA         NA       NA    
## ASV4095             NA         NA         NA       NA    
## ASV5295             NA         NA         NA       NA    
## ASV5787             NA         NA         NA       NA    
## ASV9455             NA         NA         NA       NA    
## ASV10879            NA         NA         NA       NA    
## ASV3997             NA         NA         NA       NA    
## ASV6760             NA         NA         NA       NA    
## ASV6990             NA         NA         NA       NA    
## ASV9560             NA         NA         NA       NA    
## ASV0220             NA         NA         NA       NA    
## ASV2518             NA         NA         NA       NA    
## ASV3615             NA         NA         NA       NA    
## ASV0075             NA         NA         NA       NA    
## ASV8070             NA         NA         NA       NA    
## ASV1658             NA         NA         NA       NA    
## ASV0773             NA         NA         NA       NA    
## ASV0799             NA         NA         NA       NA    
## ASV1839             NA         NA         NA       NA    
## ASV0265             NA         NA         NA       NA    
## ASV3741             NA         NA         NA       NA    
## ASV0847             NA         NA         NA       NA    
## ASV1026             NA         NA         NA       NA    
## ASV1222             NA         NA         NA       NA    
## ASV0729             NA         NA         NA       NA    
## ASV0143             NA         NA         NA       NA    
## ASV1328             NA         NA         NA       NA    
## ASV9078             NA         NA         NA       NA    
## ASV0027             NA         NA         NA       NA    
## ASV0546             NA         NA         NA       NA    
## ASV1136             NA         NA         NA       NA    
## ASV3081             NA         NA         NA       NA    
## ASV0531             NA         NA         NA       NA    
## ASV2525             NA         NA         NA       NA    
## ASV1083             NA         NA         NA       NA    
## ASV0424             NA         NA         NA       NA    
## ASV0644             NA         NA         NA       NA    
## ASV6007             NA         NA         NA       NA    
## ASV0564             NA         NA         NA       NA    
## ASV1938             NA         NA         NA       NA    
## ASV6516             NA         NA         NA       NA    
## ASV0503             NA         NA         NA       NA    
## ASV6913             NA         NA         NA       NA    
## ASV0164             NA         NA         NA       NA    
## ASV1576             NA         NA         NA       NA    
## ASV1725             NA         NA         NA       NA    
## ASV4501             NA         NA         NA       NA    
## ASV10678            NA         NA         NA       NA    
## ASV0944             NA         NA         NA       NA    
## ASV2292             NA         NA         NA       NA    
## ASV1090             NA         NA         NA       NA    
## ASV9117             NA         NA         NA       NA    
## ASV0285             NA         NA         NA       NA    
## ASV0463             NA         NA         NA       NA    
## ASV3199             NA         NA         NA       NA    
## ASV0150             NA         NA         NA       NA    
## ASV6583             NA         NA         NA       NA    
## ASV0392             NA         NA         NA       NA    
## ASV14007            NA         NA         NA       NA    
## ASV0177             NA         NA         NA       NA    
## ASV6448             NA         NA         NA       NA    
## ASV5399             NA         NA         NA       NA    
## ASV0277             NA         NA         NA       NA    
## ASV2599             NA         NA         NA       NA    
## ASV13465            NA         NA         NA       NA    
## ASV2412             NA         NA         NA       NA    
## ASV0423             NA         NA         NA       NA    
## ASV5187             NA         NA         NA       NA    
## ASV0701             NA         NA         NA       NA    
## ASV4248             NA         NA         NA       NA    
## ASV0519     -3.661e+37  1.749e+21 -2.093e+16   <2e-16 ***
## ASV0764             NA         NA         NA       NA    
## ASV5385             NA         NA         NA       NA    
## ASV3021             NA         NA         NA       NA    
## ASV4119             NA         NA         NA       NA    
## ASV2534             NA         NA         NA       NA    
## ASV1061             NA         NA         NA       NA    
## ASV0670             NA         NA         NA       NA    
## ASV1384             NA         NA         NA       NA    
## ASV1981             NA         NA         NA       NA    
## ASV9632             NA         NA         NA       NA    
## ASV4564             NA         NA         NA       NA    
## ASV5289             NA         NA         NA       NA    
## ASV0516             NA         NA         NA       NA    
## ASV1463             NA         NA         NA       NA    
## ASV0969             NA         NA         NA       NA    
## ASV1113             NA         NA         NA       NA    
## ASV1234             NA         NA         NA       NA    
## ASV3814             NA         NA         NA       NA    
## ASV1000             NA         NA         NA       NA    
## ASV0079             NA         NA         NA       NA    
## ASV0145             NA         NA         NA       NA    
## ASV0457             NA         NA         NA       NA    
## ASV1485             NA         NA         NA       NA    
## ASV0535             NA         NA         NA       NA    
## ASV0259             NA         NA         NA       NA    
## ASV0570             NA         NA         NA       NA    
## ASV0906             NA         NA         NA       NA    
## ASV1748             NA         NA         NA       NA    
## ASV5520             NA         NA         NA       NA    
## ASV2288             NA         NA         NA       NA    
## ASV1887             NA         NA         NA       NA    
## ASV0374             NA         NA         NA       NA    
## ASV0823             NA         NA         NA       NA    
## ASV0717             NA         NA         NA       NA    
## ASV0431             NA         NA         NA       NA    
## ASV1030             NA         NA         NA       NA    
## ASV1082             NA         NA         NA       NA    
## ASV2684             NA         NA         NA       NA    
## ASV0051             NA         NA         NA       NA    
## ASV0513             NA         NA         NA       NA    
## ASV0581             NA         NA         NA       NA    
## ASV7282             NA         NA         NA       NA    
## ASV3009     -2.263e+36  2.047e+20 -1.106e+16   <2e-16 ***
## ASV2106             NA         NA         NA       NA    
## ASV1012             NA         NA         NA       NA    
## ASV0921             NA         NA         NA       NA    
## ASV0010             NA         NA         NA       NA    
## ASV1178             NA         NA         NA       NA    
## ASV2848             NA         NA         NA       NA    
## ASV0586             NA         NA         NA       NA    
## ASV4225             NA         NA         NA       NA    
## ASV2156             NA         NA         NA       NA    
## ASV9778             NA         NA         NA       NA    
## ASV0493             NA         NA         NA       NA    
## ASV3770             NA         NA         NA       NA    
## ASV0470             NA         NA         NA       NA    
## ASV0262             NA         NA         NA       NA    
## ASV0998             NA         NA         NA       NA    
## ASV7708             NA         NA         NA       NA    
## ASV0453             NA         NA         NA       NA    
## ASV0044             NA         NA         NA       NA    
## ASV5490             NA         NA         NA       NA    
## ASV2638             NA         NA         NA       NA    
## ASV0829             NA         NA         NA       NA    
## ASV0601             NA         NA         NA       NA    
## ASV0234             NA         NA         NA       NA    
## ASV0133             NA         NA         NA       NA    
## ASV0323             NA         NA         NA       NA    
## ASV0854             NA         NA         NA       NA    
## ASV0110             NA         NA         NA       NA    
## ASV0816             NA         NA         NA       NA    
## ASV1031             NA         NA         NA       NA    
## ASV0144             NA         NA         NA       NA    
## ASV0020             NA         NA         NA       NA    
## ASV0962             NA         NA         NA       NA    
## ASV0794             NA         NA         NA       NA    
## ASV7117             NA         NA         NA       NA    
## ASV1008             NA         NA         NA       NA    
## ASV0096             NA         NA         NA       NA    
## ASV0128             NA         NA         NA       NA    
## ASV5232             NA         NA         NA       NA    
## ASV0031             NA         NA         NA       NA    
## ASV1744             NA         NA         NA       NA    
## ASV0289             NA         NA         NA       NA    
## ASV7413             NA         NA         NA       NA    
## ASV0822             NA         NA         NA       NA    
## ASV8111             NA         NA         NA       NA    
## ASV0687             NA         NA         NA       NA    
## ASV0112             NA         NA         NA       NA    
## ASV0987             NA         NA         NA       NA    
## ASV5332             NA         NA         NA       NA    
## ASV1129             NA         NA         NA       NA    
## ASV1274             NA         NA         NA       NA    
## ASV0119             NA         NA         NA       NA    
## ASV0890             NA         NA         NA       NA    
## ASV0848             NA         NA         NA       NA    
## ASV5944             NA         NA         NA       NA    
## ASV19741            NA         NA         NA       NA    
## ASV0504             NA         NA         NA       NA    
## ASV2146             NA         NA         NA       NA    
## ASV0089             NA         NA         NA       NA    
## ASV2301             NA         NA         NA       NA    
## ASV2982             NA         NA         NA       NA    
## ASV0891             NA         NA         NA       NA    
## ASV0093             NA         NA         NA       NA    
## ASV0042             NA         NA         NA       NA    
## ASV0980             NA         NA         NA       NA    
## ASV0069             NA         NA         NA       NA    
## ASV1364             NA         NA         NA       NA    
## ASV0524             NA         NA         NA       NA    
## ASV0435             NA         NA         NA       NA    
## ASV0517             NA         NA         NA       NA    
## ASV3167             NA         NA         NA       NA    
## ASV4280             NA         NA         NA       NA    
## ASV1158             NA         NA         NA       NA    
## ASV2214             NA         NA         NA       NA    
## ASV0544             NA         NA         NA       NA    
## ASV5326             NA         NA         NA       NA    
## ASV3765             NA         NA         NA       NA    
## ASV4646             NA         NA         NA       NA    
## ASV0090             NA         NA         NA       NA    
## ASV3680             NA         NA         NA       NA    
## ASV0111             NA         NA         NA       NA    
## ASV0768             NA         NA         NA       NA    
## ASV4862             NA         NA         NA       NA    
## ASV1742             NA         NA         NA       NA    
## ASV3701             NA         NA         NA       NA    
## ASV2386             NA         NA         NA       NA    
## ASV0375             NA         NA         NA       NA    
## ASV2796             NA         NA         NA       NA    
## ASV1369             NA         NA         NA       NA    
## ASV10272            NA         NA         NA       NA    
## ASV10354            NA         NA         NA       NA    
## ASV1067             NA         NA         NA       NA    
## ASV1900             NA         NA         NA       NA    
## ASV4079             NA         NA         NA       NA    
## ASV4149             NA         NA         NA       NA    
## ASV5140             NA         NA         NA       NA    
## ASV10782            NA         NA         NA       NA    
## ASV4273             NA         NA         NA       NA    
## ASV8121             NA         NA         NA       NA    
## ASV8438             NA         NA         NA       NA    
## ASV9390             NA         NA         NA       NA    
## ASV1340             NA         NA         NA       NA    
## ASV2650             NA         NA         NA       NA    
## ASV4674             NA         NA         NA       NA    
## ASV10492            NA         NA         NA       NA    
## ASV11430            NA         NA         NA       NA    
## ASV12135            NA         NA         NA       NA    
## ASV14970            NA         NA         NA       NA    
## ASV1954             NA         NA         NA       NA    
## ASV2613             NA         NA         NA       NA    
## ASV2757             NA         NA         NA       NA    
## ASV2909             NA         NA         NA       NA    
## ASV2954             NA         NA         NA       NA    
## ASV2969             NA         NA         NA       NA    
## ASV3410             NA         NA         NA       NA    
## ASV3575             NA         NA         NA       NA    
## ASV4275             NA         NA         NA       NA    
## ASV4652             NA         NA         NA       NA    
## ASV4761             NA         NA         NA       NA    
## ASV6003             NA         NA         NA       NA    
## ASV6110             NA         NA         NA       NA    
## ASV7427             NA         NA         NA       NA    
## ASV8092             NA         NA         NA       NA    
## ASV8169             NA         NA         NA       NA    
## ASV9693             NA         NA         NA       NA    
## ASV10913            NA         NA         NA       NA    
## ASV1979             NA         NA         NA       NA    
## ASV3772             NA         NA         NA       NA    
## ASV0113             NA         NA         NA       NA    
## ASV1800             NA         NA         NA       NA    
## ASV2335             NA         NA         NA       NA    
## ASV0692             NA         NA         NA       NA    
## ASV1120             NA         NA         NA       NA    
## ASV1434             NA         NA         NA       NA    
## ASV0076             NA         NA         NA       NA    
## ASV0361             NA         NA         NA       NA    
## ASV2231             NA         NA         NA       NA    
## ASV2018             NA         NA         NA       NA    
## ASV1529             NA         NA         NA       NA    
## ASV0841             NA         NA         NA       NA    
## ASV2556             NA         NA         NA       NA    
## ASV2777             NA         NA         NA       NA    
## ASV0355             NA         NA         NA       NA    
## ASV5169             NA         NA         NA       NA    
## ASV3091             NA         NA         NA       NA    
## ASV2435             NA         NA         NA       NA    
## ASV6822             NA         NA         NA       NA    
## ASV12605            NA         NA         NA       NA    
## ASV0286             NA         NA         NA       NA    
## ASV0074             NA         NA         NA       NA    
## ASV2485             NA         NA         NA       NA    
## ASV1233             NA         NA         NA       NA    
## ASV0356             NA         NA         NA       NA    
## ASV2918             NA         NA         NA       NA    
## ASV1427             NA         NA         NA       NA    
## ASV1409             NA         NA         NA       NA    
## ASV0770             NA         NA         NA       NA    
## ASV1403             NA         NA         NA       NA    
## ASV0314             NA         NA         NA       NA    
## ASV0187             NA         NA         NA       NA    
## ASV0313             NA         NA         NA       NA    
## ASV1087             NA         NA         NA       NA    
## ASV1970             NA         NA         NA       NA    
## ASV0754             NA         NA         NA       NA    
## ASV3775             NA         NA         NA       NA    
## ASV0132             NA         NA         NA       NA    
## ASV2329             NA         NA         NA       NA    
## ASV0561             NA         NA         NA       NA    
## ASV0130             NA         NA         NA       NA    
## ASV0226             NA         NA         NA       NA    
## ASV12648            NA         NA         NA       NA    
## ASV0204             NA         NA         NA       NA    
## ASV0767             NA         NA         NA       NA    
## ASV0335             NA         NA         NA       NA    
## ASV5901             NA         NA         NA       NA    
## ASV0596             NA         NA         NA       NA    
## ASV9271             NA         NA         NA       NA    
## ASV0904             NA         NA         NA       NA    
## ASV15270            NA         NA         NA       NA    
## ASV0990             NA         NA         NA       NA    
## ASV0155             NA         NA         NA       NA    
## ASV0086             NA         NA         NA       NA    
## ASV2581             NA         NA         NA       NA    
## ASV1579             NA         NA         NA       NA    
## ASV7730             NA         NA         NA       NA    
## ASV0897             NA         NA         NA       NA    
## ASV1975             NA         NA         NA       NA    
## ---
## Signif. codes:  0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1
## 
## (Dispersion parameter for binomial family taken to be 1)
## 
##     Null deviance:  385.39  on 277  degrees of freedom
## Residual deviance: 9443.44  on  42  degrees of freedom
## AIC: 9915.4
## 
## Number of Fisher Scoring iterations: 5
pchisq(logreg_1000$null.deviance, logreg_1000$df.null, lower.tail = FALSE)
## [1] 1.735332e-05
  • The above statistical test indicates that there is evidence for the alternative hypothesis that the model with predictors is much better than the null model with the intercept.
# Bad fit in notes example had a p-value of 0.9995629 from Ressler
# good fit would be the opposite
pchisq(logreg_1000$deviance, logreg_1000$df.residual, lower.tail = FALSE)
## [1] 0

Using top 500 ASVs to see if the model improves

# lr_clr_df %>% 
#   select(1:502) -> lr_clr_df_500 # because of id column and response column


lr_data[,1:502] -> lr_data_500
 
  
bind_cols(lr_data_500[,1:2], 
          lr_data_500[,-c(1,2)] %>% clr()
            ) -> lr_clr_df_500

dim(lr_clr_df_500)
## [1] 278 502
head(lr_clr_df_500)
## # A tibble: 6 × 502
##   sample_id  Clade ASV1236 ASV0421 ASV0691 ASV0899 ASV1004 ASV1041 ASV1058
##   <chr>      <dbl>   <dbl>   <dbl>   <dbl>   <dbl>   <dbl>   <dbl>   <dbl>
## 1 SKAU-R2-23     1    0      0       0       0      0        0       0    
## 2 SWAJ-R4-3      0    0      0       0       0      0        0       0    
## 3 SYAN-R3-19     1    0      0       0       0      0        0       0    
## 4 PMAQ-R2-19     0    0      0       0       0      0        0       0    
## 5 SDOG-R3-6      0    0      0       0       0      0        0       0    
## 6 PDOG-R2-22     0    1.38   0.912   0.421   0.556  0.0158  -0.341  -0.187
## # ℹ 493 more variables: ASV12542 <dbl>, ASV1294 <dbl>, ASV13113 <dbl>,
## #   ASV1318 <dbl>, ASV2269 <dbl>, ASV2542 <dbl>, ASV2660 <dbl>, ASV2737 <dbl>,
## #   ASV2840 <dbl>, ASV3053 <dbl>, ASV3077 <dbl>, ASV3134 <dbl>, ASV3140 <dbl>,
## #   ASV3579 <dbl>, ASV6119 <dbl>, ASV7557 <dbl>, ASV8422 <dbl>, ASV1086 <dbl>,
## #   ASV1310 <dbl>, ASV15750 <dbl>, ASV16905 <dbl>, ASV2033 <dbl>,
## #   ASV2089 <dbl>, ASV2127 <dbl>, ASV2725 <dbl>, ASV2804 <dbl>, ASV3075 <dbl>,
## #   ASV3327 <dbl>, ASV3342 <dbl>, ASV3532 <dbl>, ASV3600 <dbl>, …

Logistic with Reduced 500 ASVs

glmnet::glmnet

y = as.factor(lr_clr_df_500$Clade)
x = as.matrix(lr_clr_df_500[,-c(1,2)])

glimpse(y)
##  Factor w/ 2 levels "0","1": 2 1 2 1 1 1 1 1 2 1 ...
dim(x)
## [1] 278 500
library(glmnet)
lr_model_500 <- glmnet(x, y, 
                        family = "binomial", 
                        #alpha = 1 ,# lasso L1 norm
                        alpha = 0 # ridge L2 norm
                )
lr_model_500
## 
## Call:  glmnet(x = x, y = y, family = "binomial", alpha = 0) 
## 
##      Df  %Dev  Lambda
## 1   500  0.00 171.800
## 2   500  0.65 164.000
## 3   500  0.68 156.500
## 4   500  0.72 149.400
## 5   500  0.75 142.600
## 6   500  0.78 136.200
## 7   500  0.82 130.000
## 8   500  0.86 124.100
## 9   500  0.90 118.400
## 10  500  0.94 113.000
## 11  500  0.98 107.900
## 12  500  1.03 103.000
## 13  500  1.07  98.320
## 14  500  1.12  93.850
## 15  500  1.17  89.580
## 16  500  1.23  85.510
## 17  500  1.28  81.620
## 18  500  1.34  77.910
## 19  500  1.40  74.370
## 20  500  1.46  70.990
## 21  500  1.53  67.770
## 22  500  1.60  64.690
## 23  500  1.67  61.750
## 24  500  1.74  58.940
## 25  500  1.82  56.260
## 26  500  1.90  53.700
## 27  500  1.98  51.260
## 28  500  2.07  48.930
## 29  500  2.16  46.710
## 30  500  2.26  44.580
## 31  500  2.35  42.560
## 32  500  2.46  40.620
## 33  500  2.56  38.780
## 34  500  2.67  37.020
## 35  500  2.79  35.330
## 36  500  2.91  33.730
## 37  500  3.03  32.190
## 38  500  3.16  30.730
## 39  500  3.29  29.330
## 40  500  3.43  28.000
## 41  500  3.57  26.730
## 42  500  3.71  25.510
## 43  500  3.87  24.350
## 44  500  4.03  23.250
## 45  500  4.19  22.190
## 46  500  4.36  21.180
## 47  500  4.53  20.220
## 48  500  4.71  19.300
## 49  500  4.90  18.420
## 50  500  5.09  17.590
## 51  500  5.29  16.790
## 52  500  5.49  16.020
## 53  500  5.70  15.290
## 54  500  5.92  14.600
## 55  500  6.15  13.940
## 56  500  6.38  13.300
## 57  500  6.61  12.700
## 58  500  6.86  12.120
## 59  500  7.11  11.570
## 60  500  7.36  11.040
## 61  500  7.63  10.540
## 62  500  7.90  10.060
## 63  500  8.16   9.606
## 64  500  8.44   9.169
## 65  500  8.74   8.752
## 66  500  9.03   8.354
## 67  500  9.34   7.975
## 68  500  9.65   7.612
## 69  500  9.97   7.266
## 70  500 10.30   6.936
## 71  500 10.64   6.621
## 72  500 10.98   6.320
## 73  500 11.33   6.033
## 74  500 11.68   5.758
## 75  500 12.05   5.497
## 76  500 12.42   5.247
## 77  500 12.80   5.008
## 78  500 13.18   4.781
## 79  500 13.57   4.563
## 80  500 13.97   4.356
## 81  500 14.38   4.158
## 82  500 14.79   3.969
## 83  500 15.21   3.789
## 84  500 15.64   3.616
## 85  500 16.07   3.452
## 86  500 16.51   3.295
## 87  500 16.96   3.145
## 88  500 17.41   3.002
## 89  500 17.87   2.866
## 90  500 18.34   2.736
## 91  500 18.81   2.611
## 92  500 19.29   2.493
## 93  500 19.77   2.379
## 94  500 20.26   2.271
## 95  500 20.75   2.168
## 96  500 21.25   2.069
## 97  500 21.76   1.975
## 98  500 22.27   1.886
## 99  500 22.79   1.800
## 100 500 23.31   1.718
summary(lr_model_500)
##            Length Class     Mode     
## a0           100  -none-    numeric  
## beta       50000  dgCMatrix S4       
## df           100  -none-    numeric  
## dim            2  -none-    numeric  
## lambda       100  -none-    numeric  
## dev.ratio    100  -none-    numeric  
## nulldev        1  -none-    numeric  
## npasses        1  -none-    numeric  
## jerr           1  -none-    numeric  
## offset         1  -none-    logical  
## classnames     2  -none-    character
## call           5  -none-    call     
## nobs           1  -none-    numeric
plot(lr_model_500)

#plot(lr_model_500, xlim = c(0, 50), ylim = c(-0.02, 0.02))

Cross-Validation

cv_results_500 <- cv.glmnet(x, y,
                        family = "binomial",
                        nfolds = 10)
plot(cv_results_500)

best_lambda_500 <- lr_model_500$lambda.min

# Refit the model with the selected lambda
best_model_500 <- glmnet(x, y, family = "binomial", alpha = 0, lambda = best_lambda_500)

coefficients(best_model_500)
## 501 x 100 sparse Matrix of class "dgCMatrix"
##   [[ suppressing 100 column names 's0', 's1', 's2' ... ]]
##                                                                    
## (Intercept) -1.249001e-16  7.230358e-03  7.573680e-03  7.929354e-03
## ASV1236      2.487736e-37  1.463110e-03  1.532663e-03  1.603685e-03
## ASV0421      2.256405e-38  1.443794e-04  1.512077e-04  1.588388e-04
## ASV0691     -2.053902e-37 -1.184307e-03 -1.240601e-03 -1.296807e-03
## ASV0899      2.141697e-37  1.262958e-03  1.323022e-03  1.384483e-03
## ASV1004      4.960527e-37  2.922185e-03  3.061099e-03  3.203124e-03
## ASV1041     -2.046369e-37 -1.204711e-03 -1.261847e-03 -1.320366e-03
## ASV1058      3.102249e-37  1.826193e-03  1.912922e-03  2.001604e-03
## ASV12542     1.226446e-37  7.171132e-04  7.512680e-04  7.858314e-04
## ASV1294      2.883128e-37  1.698038e-03  1.778655e-03  1.861164e-03
## ASV13113     8.911866e-38  5.392071e-04  5.648677e-04  5.918199e-04
## ASV1318      2.876637e-37  1.693994e-03  1.774347e-03  1.856655e-03
## ASV2269     -4.993241e-37 -2.938835e-03 -3.077379e-03 -3.220177e-03
## ASV2542      2.317035e-37  1.386484e-03  1.452256e-03  1.520778e-03
## ASV2660     -1.997156e-37 -1.173354e-03 -1.228690e-03 -1.285566e-03
## ASV2737      7.166447e-38  4.155459e-04  4.355030e-04  4.553414e-04
## ASV2840      2.714301e-37  1.584306e-03  1.659334e-03  1.735538e-03
## ASV3053      1.377147e-36  8.061227e-03  8.442035e-03  8.830942e-03
## ASV3077      8.757045e-38  5.130382e-04  5.373373e-04  5.621007e-04
## ASV3134      1.443337e-37  8.688657e-04  9.101903e-04  9.533946e-04
## ASV3140      2.022261e-37  1.203838e-03  1.260835e-03  1.320019e-03
## ASV3579      6.644802e-38  4.061470e-04  4.255919e-04  4.460977e-04
## ASV6119     -1.366643e-37 -8.043544e-04 -8.422099e-04 -8.812870e-04
## ASV7557     -2.777344e-37 -1.634640e-03 -1.711449e-03 -1.790852e-03
## ASV8422      7.020134e-38  4.107460e-04  4.304933e-04  4.503067e-04
## ASV1086     -1.179996e-38 -6.733132e-05 -7.055854e-05 -7.369918e-05
## ASV1310      1.328433e-37  7.820533e-04  8.191971e-04  8.571729e-04
## ASV15750    -1.897072e-38 -1.100230e-04 -1.150947e-04 -1.203567e-04
## ASV16905    -5.711172e-38 -3.361378e-04 -3.519328e-04 -3.682600e-04
## ASV2033      2.302796e-37  1.382955e-03  1.448850e-03  1.517448e-03
## ASV2089      1.203196e-37  7.083884e-04  7.416680e-04  7.760912e-04
## ASV2127      3.905460e-37  2.298912e-03  2.407907e-03  2.519534e-03
## ASV2725      3.164200e-37  1.854292e-03  1.942307e-03  2.031907e-03
## ASV2804     -1.182307e-37 -6.958605e-04 -7.285275e-04 -7.623248e-04
## ASV3075      2.531982e-37  1.501481e-03  1.572816e-03  1.646310e-03
## ASV3327      3.424690e-37  2.047582e-03  2.145166e-03  2.246269e-03
## ASV3342      2.961100e-37  1.766850e-03  1.850597e-03  1.937666e-03
## ASV3532     -3.300146e-37 -1.962344e-03 -2.054883e-03 -2.151232e-03
## ASV3600      1.527807e-37  9.094804e-04  9.527511e-04  9.974474e-04
## ASV4013      2.900367e-37  1.716052e-03  1.797531e-03  1.881309e-03
## ASV4136      3.172587e-37  1.860046e-03  1.947995e-03  2.037938e-03
## ASV4195      1.206964e-36  7.103729e-03  7.436558e-03  7.781518e-03
## ASV4407     -4.663522e-37 -2.744770e-03 -2.873165e-03 -3.006434e-03
## ASV4717      8.506359e-38  4.915469e-04  5.154315e-04  5.388225e-04
## ASV6794      1.975909e-37  1.152569e-03  1.207509e-03  1.262924e-03
## ASV8324     -2.392925e-37 -1.408383e-03 -1.474284e-03 -1.542664e-03
## ASV8981     -8.352057e-39 -4.426868e-05 -4.614359e-05 -4.803271e-05
## ASV9859      7.364704e-38  4.523909e-04  4.741369e-04  4.971056e-04
## ASV0936      2.228490e-37  1.330932e-03  1.393841e-03  1.459488e-03
## ASV12683     6.041569e-40  1.425662e-06  1.778646e-06  1.737172e-06
## ASV1293      1.555205e-37  9.143034e-04  9.575095e-04  1.001843e-03
## ASV13055    -5.436579e-39 -2.863881e-05 -2.958808e-05 -3.079128e-05
## ASV17063    -1.241828e-37 -7.308914e-04 -7.648828e-04 -8.003506e-04
## ASV2228      1.012776e-37  5.960806e-04  6.237582e-04  6.526799e-04
## ASV2769      1.316397e-38  8.300106e-05  8.731841e-05  9.164733e-05
## ASV2803      1.125761e-37  6.553723e-04  6.867086e-04  7.181488e-04
## ASV2896      8.363712e-38  5.000113e-04  5.238930e-04  5.485832e-04
## ASV3062      9.679797e-38  5.878085e-04  6.162170e-04  6.457210e-04
## ASV3107      1.568591e-37  9.359311e-04  9.804783e-04  1.026589e-03
## ASV3265      2.228976e-37  1.309662e-03  1.371569e-03  1.435018e-03
## ASV3666      2.400919e-39  1.334049e-05  1.432574e-05  1.493994e-05
## ASV4497      7.580134e-38  4.467574e-04  4.681643e-04  4.898883e-04
## ASV6914     -9.734870e-39 -6.102543e-05 -6.366593e-05 -6.682414e-05
## ASV0576     -2.743255e-37 -1.593636e-03 -1.669158e-03 -1.745420e-03
## ASV0673      2.900369e-37  1.714445e-03  1.795632e-03  1.879238e-03
## ASV0772      1.338351e-37  7.925904e-04  8.302808e-04  8.690117e-04
## ASV0862      6.088647e-39  5.090383e-05  5.333672e-05  5.662393e-05
## ASV0898      9.946095e-38  5.989665e-04  6.274025e-04  6.572056e-04
## ASV0910      1.169851e-37  6.994155e-04  7.326333e-04  7.671623e-04
## ASV0964     -1.025694e-37 -5.982967e-04 -6.267623e-04 -6.555049e-04
## ASV10059     8.090263e-38  4.887691e-04  5.121472e-04  5.365449e-04
## ASV10263    -1.890019e-37 -1.112391e-03 -1.164591e-03 -1.218597e-03
## ASV1088      2.104846e-37  1.253932e-03  1.313475e-03  1.375157e-03
## ASV1101      2.708230e-37  1.592160e-03  1.667505e-03  1.744687e-03
## ASV1183      6.943282e-38  4.128824e-04  4.323342e-04  4.526033e-04
## ASV11956     7.183437e-38  4.166133e-04  4.365471e-04  4.564495e-04
## ASV12774     6.039882e-39  3.109980e-05  3.268507e-05  3.395460e-05
## ASV1321      2.999660e-37  1.797893e-03  1.883460e-03  1.972451e-03
## ASV13793    -1.303199e-37 -7.670116e-04 -8.029863e-04 -8.402204e-04
## ASV14482     9.146381e-39  5.177452e-05  5.435880e-05  5.676294e-05
## ASV15483     5.138747e-38  3.069552e-04  3.216649e-04  3.368064e-04
## ASV2062      2.465653e-37  1.457710e-03  1.526585e-03  1.597681e-03
## ASV2132      1.960660e-37  1.170330e-03  1.226003e-03  1.283687e-03
## ASV2413      1.928046e-37  1.135153e-03  1.188761e-03  1.243870e-03
## ASV2490      6.044612e-37  3.535343e-03  3.702192e-03  3.872612e-03
## ASV2594      7.224511e-38  4.293504e-04  4.497035e-04  4.707606e-04
## ASV2822     -3.438221e-37 -2.023601e-03 -2.118813e-03 -2.217071e-03
## ASV2863      3.691454e-37  2.165241e-03  2.266918e-03  2.371611e-03
## ASV2910      1.341449e-37  7.886411e-04  8.260423e-04  8.642782e-04
## ASV2980      1.470464e-37  8.703498e-04  9.113833e-04  9.538976e-04
## ASV3307      2.736224e-37  1.610433e-03  1.685972e-03  1.764146e-03
## ASV3474      1.702363e-37  1.023809e-03  1.072548e-03  1.123404e-03
## ASV3502      1.850029e-37  1.098767e-03  1.150861e-03  1.204721e-03
## ASV4236      2.853685e-37  1.667402e-03  1.745495e-03  1.825714e-03
## ASV4842     -2.808639e-38 -1.696588e-04 -1.777450e-04 -1.862407e-04
## ASV4894     -1.303199e-37 -7.670113e-04 -8.030663e-04 -8.403055e-04
## ASV5290      9.977313e-38  5.949107e-04  6.232675e-04  6.525590e-04
## ASV5501      6.181106e-38  3.667380e-04  3.840667e-04  4.020066e-04
## ASV5795      6.687574e-38  3.991943e-04  4.181489e-04  4.378147e-04
## ASV5987     -3.639689e-37 -2.142177e-03 -2.242998e-03 -2.347014e-03
## ASV6267     -4.101457e-37 -2.413954e-03 -2.527386e-03 -2.644584e-03
## ASV6862      1.673295e-37  9.787335e-04  1.024940e-03  1.072122e-03
## ASV7145      7.508590e-38  4.365964e-04  4.570309e-04  4.779158e-04
## ASV7673     -1.303199e-37 -7.670111e-04 -8.030433e-04 -8.402803e-04
## ASV7789      5.783507e-38  3.543060e-04  3.713142e-04  3.892490e-04
## ASV7809      1.757340e-39  1.580454e-05  1.673353e-05  1.778828e-05
## ASV8002     -1.645936e-37 -9.687325e-04 -1.014213e-03 -1.061242e-03
## ASV8205      6.668736e-38  3.969001e-04  4.158856e-04  4.353895e-04
## ASV9155     -4.257445e-38 -2.491214e-04 -2.607313e-04 -2.727482e-04
## ASV9221      1.231155e-38  8.180940e-05  8.599872e-05  9.047087e-05
## ASV9311     -2.640533e-37 -1.554112e-03 -1.626993e-03 -1.702434e-03
## ASV9557     -1.804719e-37 -1.062186e-03 -1.111918e-03 -1.163472e-03
## ASV9936     -3.639689e-37 -2.142176e-03 -2.242314e-03 -2.346273e-03
## ASV1445      2.135517e-37  1.272034e-03  1.332463e-03  1.395013e-03
## ASV4232      7.778344e-38  4.695706e-04  4.919761e-04  5.153997e-04
## ASV6479      2.320402e-38  1.500966e-04  1.575118e-04  1.655191e-04
## ASV0142     -1.578646e-37 -9.267364e-04 -9.704482e-04 -1.015296e-03
## ASV0378      6.612904e-38  3.996131e-04  4.186946e-04  4.386577e-04
## ASV1122      2.054769e-37  1.226596e-03  1.284824e-03  1.345276e-03
## ASV0123     -1.396268e-37 -8.192738e-04 -8.578535e-04 -8.974746e-04
## ASV2064      7.388904e-38  4.285596e-04  4.487405e-04  4.691962e-04
## ASV4459     -1.114934e-38 -6.308509e-05 -6.590210e-05 -6.883594e-05
## ASV0448      5.279280e-38  3.192338e-04  3.344890e-04  3.504475e-04
## ASV0397      1.231244e-37  7.299771e-04  7.645961e-04  8.003188e-04
## ASV0485      1.447589e-37  8.547848e-04  8.951634e-04  9.368023e-04
## ASV1566      2.112454e-37  1.251630e-03  1.310918e-03  1.372107e-03
## ASV1365      1.784911e-37  1.061585e-03  1.111986e-03  1.164099e-03
## ASV1065      2.543300e-37  1.511342e-03  1.582767e-03  1.656884e-03
## ASV0722     -1.286640e-38 -7.719078e-05 -8.094111e-05 -8.476776e-05
## ASV12660    -1.520279e-37 -8.903256e-04 -9.322547e-04 -9.752425e-04
## ASV0223      3.987436e-38  2.356668e-04  2.467827e-04  2.582761e-04
## ASV0229      5.909607e-38  3.529198e-04  3.696309e-04  3.870359e-04
## ASV0877      2.709244e-38  1.568353e-04  1.645104e-04  1.719975e-04
## ASV0983      1.443019e-37  8.509497e-04  8.910979e-04  9.324839e-04
## ASV0626      1.069392e-38  7.289410e-05  7.678054e-05  8.086968e-05
## ASV4146      7.018615e-39  4.151662e-05  4.374779e-05  4.578268e-05
## ASV4175     -1.721376e-37 -1.027050e-03 -1.075432e-03 -1.126010e-03
## ASV2082     -6.886168e-38 -4.283149e-04 -4.492945e-04 -4.713425e-04
## ASV2272      8.243704e-38  4.905654e-04  5.138670e-04  5.379655e-04
## ASV2245     -1.222952e-37 -7.311238e-04 -7.655222e-04 -8.015989e-04
## ASV0590     -6.226416e-38 -3.938630e-04 -4.131619e-04 -4.337626e-04
## ASV0217     -2.467240e-41  1.339699e-05  1.435210e-05  1.573859e-05
## ASV0416      1.022443e-37  5.911662e-04  6.187600e-04  6.468749e-04
## ASV1056      1.166672e-37  7.004618e-04  7.339129e-04  7.686572e-04
## ASV7777     -1.685134e-37 -1.003358e-03 -1.050450e-03 -1.099744e-03
## ASV0455      3.043615e-38  1.808809e-04  1.893311e-04  1.981965e-04
## ASV0604      7.589291e-38  4.575182e-04  4.795244e-04  5.023255e-04
## ASV6100     -1.147947e-37 -6.861864e-04 -7.185141e-04 -7.523714e-04
## ASV11359    -2.493585e-37 -1.485498e-03 -1.555238e-03 -1.628250e-03
## ASV6604      3.353780e-38  2.018193e-04  2.115230e-04  2.215616e-04
## ASV5004     -8.938067e-38 -5.310547e-04 -5.558352e-04 -5.818549e-04
## ASV1483     -3.871356e-38 -2.297429e-04 -2.403053e-04 -2.515376e-04
## ASV9773     -1.118380e-37 -6.671445e-04 -6.985275e-04 -7.313681e-04
## ASV4059     -4.627373e-39 -1.756683e-05 -1.792067e-05 -1.823591e-05
## ASV1193      1.371693e-37  8.136857e-04  8.522776e-04  8.921136e-04
## ASV4610     -2.860207e-38 -1.548438e-04 -1.616953e-04 -1.684791e-04
## ASV0742     -1.865581e-38 -9.910372e-05 -1.032411e-04 -1.074527e-04
## ASV1502     -2.642974e-39 -2.329354e-05 -2.429901e-05 -2.583092e-05
## ASV0195      5.522991e-39  2.812831e-05  2.929936e-05  3.042629e-05
## ASV1213      1.021583e-37  5.948943e-04  6.223120e-04  6.508035e-04
## ASV1648     -1.033114e-37 -6.171668e-04 -6.461190e-04 -6.765420e-04
## ASV6984     -9.658686e-38 -5.771515e-04 -6.041988e-04 -6.326545e-04
## ASV0396     -8.034235e-39 -4.236190e-05 -4.432414e-05 -4.612056e-05
## ASV4297      1.458189e-37  8.530452e-04  8.934451e-04  9.345828e-04
## ASV2622      2.222363e-37  1.308347e-03  1.370090e-03  1.433605e-03
## ASV3512      7.742848e-38  4.741364e-04  4.970795e-04  5.211016e-04
## ASV2411      1.429132e-37  8.590270e-04  8.996739e-04  9.423115e-04
## ASV2291     -5.259632e-38 -3.353697e-04 -3.523668e-04 -3.700822e-04
## ASV0807      2.019113e-37  1.197978e-03  1.254793e-03  1.313458e-03
## ASV1292      5.260610e-38  3.041582e-04  3.181740e-04  3.326248e-04
## ASV1035      1.910905e-37  1.121293e-03  1.173809e-03  1.228025e-03
## ASV0070     -6.717654e-40  7.815653e-07  8.764265e-07  1.168480e-06
## ASV0255      1.878239e-38  1.089702e-04  1.139941e-04  1.191901e-04
## ASV0057     -5.375019e-38 -3.130531e-04 -3.277379e-04 -3.427506e-04
## ASV0077     -1.226748e-38 -6.969763e-05 -7.296237e-05 -7.621129e-05
## ASV0625      1.106794e-37  6.482927e-04  6.786492e-04  7.099303e-04
## ASV2464      7.574062e-37  4.425745e-03  4.632815e-03  4.845823e-03
## ASV1315      1.852940e-37  1.115459e-03  1.168617e-03  1.224096e-03
## ASV2673      1.587187e-37  9.559326e-04  1.001518e-03  1.049089e-03
## ASV2161      6.737911e-38  4.051060e-04  4.245017e-04  4.446316e-04
## ASV0337     -3.937361e-38 -2.350015e-04 -2.462519e-04 -2.578392e-04
## ASV7680     -2.563213e-37 -1.532316e-03 -1.604390e-03 -1.679983e-03
## ASV0611      1.429891e-37  8.547201e-04  8.953520e-04  9.375461e-04
## ASV3118     -1.447142e-37 -8.737759e-04 -9.149547e-04 -9.585148e-04
## ASV1284      6.892387e-38  3.779544e-04  3.946359e-04  4.114370e-04
## ASV0889      1.122835e-37  6.619902e-04  6.933899e-04  7.255900e-04
## ASV4649     -5.498583e-38 -3.271355e-04 -3.424530e-04 -3.585053e-04
## ASV1108     -1.069249e-37 -6.484139e-04 -6.791240e-04 -7.116065e-04
## ASV0738      5.575283e-38  3.456115e-04  3.621400e-04  3.798475e-04
## ASV0473     -9.838163e-39 -6.455051e-05 -6.791654e-05 -7.141922e-05
## ASV0598     -2.732378e-38 -1.719092e-04 -1.803882e-04 -1.893474e-04
## ASV0429      8.435277e-38  4.954548e-04  5.187945e-04  5.427815e-04
## ASV1549      1.462435e-37  8.813309e-04  9.232720e-04  9.671513e-04
## ASV1203      1.215512e-37  7.183730e-04  7.520381e-04  7.870386e-04
## ASV4532      6.312191e-39  3.479334e-05  3.647707e-05  3.804723e-05
## ASV0274      1.919434e-38  1.177399e-04  1.233509e-04  1.293179e-04
## ASV0163     -9.654467e-38 -5.646735e-04 -5.910525e-04 -6.182524e-04
## ASV1298      1.163196e-38  6.582687e-05  6.866742e-05  7.170660e-05
## ASV9424     -1.979031e-37 -1.184641e-03 -1.240492e-03 -1.299024e-03
## ASV0412      2.121998e-37  1.250738e-03  1.309651e-03  1.370441e-03
## ASV0284      4.776264e-38  2.743042e-04  2.869733e-04  2.999085e-04
## ASV0620     -3.805121e-38 -2.362331e-04 -2.474398e-04 -2.595529e-04
## ASV0153     -1.955205e-37 -1.178042e-03 -1.234464e-03 -1.293131e-03
## ASV0498      7.037437e-38  4.211623e-04  4.410366e-04  4.618384e-04
## ASV0097      3.845139e-38  2.316478e-04  2.426316e-04  2.541582e-04
## ASV0104     -2.841211e-37 -1.683265e-03 -1.763082e-03 -1.845380e-03
## ASV1282      1.007173e-37  5.906649e-04  6.186857e-04  6.472497e-04
## ASV3883     -7.187674e-38 -4.394211e-04 -4.602827e-04 -4.824736e-04
## ASV0801      3.760145e-38  2.250749e-04  2.354671e-04  2.465699e-04
## ASV1611     -1.758382e-37 -1.056140e-03 -1.106072e-03 -1.158448e-03
## ASV0227     -2.801017e-38 -1.767251e-04 -1.853696e-04 -1.945910e-04
## ASV0833      6.076003e-38  3.627451e-04  3.799307e-04  3.978087e-04
## ASV0718      2.732113e-37  1.627699e-03  1.704635e-03  1.784672e-03
## ASV1139      4.099438e-38  2.315783e-04  2.421104e-04  2.528084e-04
## ASV0766     -3.558707e-38 -2.180584e-04 -2.283344e-04 -2.393652e-04
## ASV2091      2.321535e-37  1.360213e-03  1.424209e-03  1.489886e-03
## ASV1238     -2.004915e-37 -1.200648e-03 -1.257052e-03 -1.316389e-03
## ASV9193     -1.465827e-38 -9.832895e-05 -1.028894e-04 -1.082876e-04
## ASV0290      3.259335e-38  1.858275e-04  1.945680e-04  2.032742e-04
## ASV0231      8.351338e-38  4.924152e-04  5.155187e-04  5.394514e-04
## ASV0185      4.297712e-38  2.658654e-04  2.786276e-04  2.922255e-04
## ASV2330      9.855876e-38  5.747612e-04  6.017663e-04  6.293737e-04
## ASV3119     -3.916122e-38 -2.416953e-04 -2.532771e-04 -2.656079e-04
## ASV2368     -1.010761e-37 -6.093636e-04 -6.381468e-04 -6.684842e-04
## ASV0122     -5.149139e-38 -3.043439e-04 -3.188158e-04 -3.336630e-04
## ASV1044      1.266487e-37  7.605964e-04  7.967528e-04  8.344835e-04
## ASV0160     -5.728985e-38 -3.343060e-04 -3.499582e-04 -3.660236e-04
## ASV0326      1.419877e-38  8.483459e-05  8.892509e-05  9.311489e-05
## ASV1388      2.661082e-37  1.575669e-03  1.650190e-03  1.727169e-03
## ASV0792      2.012867e-37  1.183614e-03  1.239071e-03  1.296425e-03
## ASV0036     -5.858506e-38 -3.531615e-04 -3.700859e-04 -3.876831e-04
## ASV2125      1.892306e-37  1.122677e-03  1.175791e-03  1.230754e-03
## ASV1075     -2.883794e-39 -1.703759e-05 -1.778007e-05 -1.860677e-05
## ASV0390      9.693699e-38  5.840434e-04  6.117017e-04  6.407636e-04
## ASV3790     -1.407895e-37 -8.411432e-04 -8.808344e-04 -9.223117e-04
## ASV1535     -3.762637e-38 -2.315193e-04 -2.425484e-04 -2.543186e-04
## ASV0263      1.743826e-37  1.037556e-03  1.086346e-03  1.137272e-03
## ASV0675      2.570800e-37  1.540279e-03  1.613279e-03  1.689482e-03
## ASV3348      1.987912e-38  1.211834e-04  1.270920e-04  1.332075e-04
## ASV0058     -7.891385e-38 -4.668307e-04 -4.888627e-04 -5.116433e-04
## ASV4142      1.126786e-37  6.625684e-04  6.935596e-04  7.256603e-04
## ASV0059     -6.393267e-38 -3.774386e-04 -3.952055e-04 -4.135802e-04
## ASV0013     -1.114941e-37 -6.628337e-04 -6.942073e-04 -7.267301e-04
## ASV0033     -5.109579e-38 -3.076555e-04 -3.223457e-04 -3.376527e-04
## ASV4354     -6.571066e-38 -3.904904e-04 -4.088786e-04 -4.280248e-04
## ASV0022     -4.319647e-38 -2.600019e-04 -2.723832e-04 -2.853120e-04
## ASV0134     -3.987205e-38 -2.427574e-04 -2.543763e-04 -2.665949e-04
## ASV0415      5.535393e-39  3.589496e-05  3.760332e-05  3.951705e-05
## ASV10103    -2.427975e-37 -1.455483e-03 -1.523921e-03 -1.595922e-03
## ASV1613      1.905729e-37  1.121165e-03  1.173826e-03  1.228191e-03
## ASV0135     -2.519496e-38 -1.467436e-04 -1.535952e-04 -1.606303e-04
## ASV0469     -2.434666e-37 -1.437605e-03 -1.505082e-03 -1.575070e-03
## ASV0471      1.457385e-37  8.658694e-04  9.066789e-04  9.491206e-04
## ASV0451     -1.973660e-38 -1.260963e-04 -1.323736e-04 -1.390394e-04
## ASV0747      8.198660e-38  4.891168e-04  5.122936e-04  5.363826e-04
## ASV1314     -7.984945e-38 -4.817774e-04 -5.046420e-04 -5.286550e-04
## ASV0425     -3.063841e-37 -1.798405e-03 -1.882781e-03 -1.969769e-03
## ASV0559     -7.382613e-38 -4.371852e-04 -4.578798e-04 -4.792479e-04
## ASV0148     -1.931395e-38 -1.088920e-04 -1.139150e-04 -1.189401e-04
## ASV0129      1.191198e-38  8.197871e-05  8.609986e-05  9.072092e-05
## ASV1072      2.141224e-38  1.234709e-04  1.292125e-04  1.350631e-04
## ASV2390      1.593036e-37  9.302376e-04  9.739339e-04  1.018677e-03
## ASV0548      1.005460e-37  5.966859e-04  6.249110e-04  6.541314e-04
## ASV0168     -5.242578e-38 -3.093973e-04 -3.239474e-04 -3.390039e-04
## ASV0066     -5.861555e-38 -3.468855e-04 -3.632677e-04 -3.802021e-04
## ASV0468     -3.053753e-38 -1.818375e-04 -1.903694e-04 -1.993007e-04
## ASV0172     -1.903764e-38 -1.095500e-04 -1.146270e-04 -1.198056e-04
## ASV0236     -9.992333e-39 -4.488775e-05 -4.660596e-05 -4.802511e-05
## ASV0250      7.571720e-38  4.628165e-04  4.849753e-04  5.083625e-04
## ASV0338      3.718700e-38  2.245425e-04  2.352380e-04  2.464362e-04
## ASV0450     -5.731817e-39 -3.734207e-05 -3.920731e-05 -4.121702e-05
## ASV0377      7.345460e-38  4.342218e-04  4.546515e-04  4.758185e-04
## ASV1022     -3.307092e-39 -1.918509e-05 -2.012309e-05 -2.104068e-05
## ASV6174     -9.332835e-40 -6.886196e-06 -7.217684e-06 -7.624210e-06
## ASV0786     -7.141770e-39 -4.892823e-05 -5.140045e-05 -5.414716e-05
## ASV0053     -7.786690e-38 -4.637098e-04 -4.856406e-04 -5.084320e-04
## ASV0697     -4.907666e-38 -2.884571e-04 -3.020043e-04 -3.159803e-04
## ASV0785      1.016768e-37  6.012013e-04  6.295188e-04  6.588368e-04
## ASV1967     -1.019087e-37 -6.003672e-04 -6.287024e-04 -6.578718e-04
## ASV0385      3.188691e-38  1.931104e-04  2.023293e-04  2.119921e-04
## ASV0295      3.862899e-39  2.741194e-05  2.881195e-05  3.039618e-05
## ASV0072     -7.988702e-38 -4.705554e-04 -4.926491e-04 -5.154958e-04
## ASV0157     -1.300473e-38 -7.072020e-05 -7.389205e-05 -7.700492e-05
## ASV0501      1.676473e-37  9.994465e-04  1.046677e-03  1.095848e-03
## ASV10729    -2.094782e-37 -1.251596e-03 -1.310647e-03 -1.372364e-03
## ASV1470      1.144144e-37  6.668228e-04  6.979273e-04  7.299179e-04
## ASV0050     -1.854993e-37 -1.097961e-03 -1.149643e-03 -1.203241e-03
## ASV0411     -4.009871e-38 -2.411076e-04 -2.525557e-04 -2.645307e-04
## ASV0549      6.511330e-38  3.900188e-04  4.085314e-04  4.278235e-04
## ASV0184      2.252827e-38  1.332424e-04  1.394758e-04  1.459728e-04
## ASV0705      4.510978e-38  2.657024e-04  2.781793e-04  2.910781e-04
## ASV1715      9.267972e-38  5.516787e-04  5.776847e-04  6.047799e-04
## ASV0603      1.411258e-38  8.468011e-05  8.865414e-05  9.284869e-05
## ASV0826      1.582171e-37  9.378959e-04  9.820845e-04  1.027947e-03
## ASV0034     -5.148868e-38 -3.035497e-04 -3.177633e-04 -3.325123e-04
## ASV0838      4.178937e-38  2.335519e-04  2.439219e-04  2.545458e-04
## ASV0614     -4.340930e-38 -2.570851e-04 -2.692118e-04 -2.817717e-04
## ASV0014     -1.144131e-37 -6.791490e-04 -7.111195e-04 -7.443738e-04
## ASV0585      1.826093e-38  9.647831e-05  1.006176e-04  1.046908e-04
## ASV0016     -1.195252e-37 -7.095329e-04 -7.428818e-04 -7.776211e-04
## ASV5394     -8.850160e-38 -5.276811e-04 -5.526070e-04 -5.785732e-04
## ASV0666      2.009595e-37  1.181210e-03  1.236316e-03  1.293511e-03
## ASV2085      5.439281e-38  3.028759e-04  3.164214e-04  3.301607e-04
## ASV0003     -8.157635e-38 -4.841364e-04 -5.068479e-04 -5.305414e-04
## ASV0346      3.905374e-38  2.359203e-04  2.471928e-04  2.589691e-04
## ASV0267     -2.173813e-39 -9.116255e-06 -9.356982e-06 -9.591180e-06
## ASV0353      6.309995e-38  3.788903e-04  3.968319e-04  4.156171e-04
## ASV2419      1.769784e-37  1.047329e-03  1.096401e-03  1.147500e-03
## ASV0447      9.216880e-38  5.542351e-04  5.805225e-04  6.080454e-04
## ASV0654      1.412624e-37  8.390911e-04  8.786045e-04  9.197196e-04
## ASV0151      1.665659e-38  1.034543e-04  1.085482e-04  1.138710e-04
## ASV0065     -5.519710e-38 -3.267339e-04 -3.420816e-04 -3.580309e-04
## ASV0527      1.350566e-37  8.009143e-04  8.384945e-04  8.776610e-04
## ASV4055     -1.974189e-38 -1.203416e-04 -1.261262e-04 -1.321956e-04
## ASV0166     -6.955998e-38 -4.089450e-04 -4.279609e-04 -4.477605e-04
## ASV0417     -2.956752e-38 -1.715149e-04 -1.794565e-04 -1.876376e-04
## ASV0078     -4.090211e-38 -2.411236e-04 -2.523936e-04 -2.641067e-04
## ASV0322     -8.960153e-39 -4.992202e-05 -5.219113e-05 -5.445354e-05
## ASV0156     -9.370606e-38 -5.596779e-04 -5.861120e-04 -6.137043e-04
## ASV0648     -2.023777e-37 -1.211286e-03 -1.268517e-03 -1.328362e-03
## ASV0407     -1.479131e-38 -8.934823e-05 -9.358334e-05 -9.804143e-05
## ASV2030     -3.536766e-38 -2.075585e-04 -2.174554e-04 -2.275109e-04
## ASV0300      2.357716e-38  1.423480e-04  1.491425e-04  1.562439e-04
## ASV1150      4.764031e-39  2.995171e-05  3.143174e-05  3.299024e-05
## ASV0958      7.274455e-38  4.393959e-04  4.603056e-04  4.822347e-04
## ASV0216     -8.582464e-38 -5.066608e-04 -5.303022e-04 -5.549537e-04
## ASV0446      1.246175e-37  7.461772e-04  7.814285e-04  8.183083e-04
## ASV0367     -8.263763e-38 -4.926016e-04 -5.158270e-04 -5.400581e-04
## ASV0200     -4.922115e-38 -2.932591e-04 -3.071086e-04 -3.215282e-04
## ASV0334     -3.027654e-38 -1.727622e-04 -1.805530e-04 -1.886264e-04
## ASV1311      3.526997e-38  2.039794e-04  2.132884e-04  2.229713e-04
## ASV0458      5.285389e-38  3.038410e-04  3.179124e-04  3.322596e-04
## ASV1371      7.091460e-39  4.371276e-05  4.582620e-05  4.805383e-05
## ASV0418      1.145543e-37  6.721964e-04  7.033733e-04  7.358468e-04
## ASV0004      1.669304e-38  9.775465e-05  1.023122e-04  1.070265e-04
## ASV1943      3.422200e-37  1.952453e-03  2.045305e-03  2.136935e-03
## ASV1495     -1.685522e-38 -1.112390e-04 -1.169275e-04 -1.229938e-04
## ASV0901     -9.122558e-38 -5.470751e-04 -5.730404e-04 -6.001376e-04
## ASV0628      5.273977e-38  3.072057e-04  3.213758e-04  3.360889e-04
## ASV0400      3.109193e-38  1.830940e-04  1.916298e-04  2.005104e-04
## ASV0116     -2.688359e-38 -1.611194e-04 -1.687463e-04 -1.767198e-04
## ASV0788      2.370229e-37  1.421841e-03  1.489192e-03  1.559622e-03
## ASV0117      1.692961e-38  1.027255e-04  1.076397e-04  1.127914e-04
## ASV3137     -5.849273e-39 -3.444460e-05 -3.604253e-05 -3.771272e-05
## ASV0001      1.801421e-38  1.053356e-04  1.102138e-04  1.152822e-04
## ASV1651      5.087798e-38  2.983952e-04  3.122584e-04  3.266676e-04
## ASV1692      1.977247e-37  1.185435e-03  1.241582e-03  1.300267e-03
## ASV0660      7.736619e-38  4.492691e-04  4.699192e-04  4.913552e-04
## ASV0508      3.992253e-39  2.292393e-05  2.398614e-05  2.506736e-05
## ASV1660     -3.744589e-38 -2.298139e-04 -2.409097e-04 -2.525737e-04
## ASV0233      6.222044e-38  3.705611e-04  3.879957e-04  4.062027e-04
## ASV1343     -1.129694e-37 -6.764917e-04 -7.085014e-04 -7.419475e-04
## ASV0209      6.012786e-38  3.518096e-04  3.681367e-04  3.850787e-04
## ASV0193     -6.970993e-38 -4.089923e-04 -4.278996e-04 -4.476470e-04
## ASV0357      2.289726e-38  1.420846e-04  1.489842e-04  1.562818e-04
## ASV0198      5.180974e-38  3.061923e-04  3.205042e-04  3.354184e-04
## ASV0007      1.612598e-38  9.384932e-05  9.816925e-05  1.026593e-04
## ASV1772     -2.435500e-38 -1.411582e-04 -1.476780e-04 -1.543975e-04
## ASV0009      1.352346e-38  7.830943e-05  8.188994e-05  8.561368e-05
## ASV0006     -1.303931e-38 -7.892340e-05 -8.271296e-05 -8.666274e-05
## ASV0011     -4.678327e-38 -2.797744e-04 -2.929771e-04 -3.067865e-04
## ASV0015      1.022283e-38  5.918028e-05  6.190726e-05  6.472250e-05
## ASV0017      1.150885e-38  6.664414e-05  6.970346e-05  7.287401e-05
## ASV0235     -4.295050e-38 -2.574590e-04 -2.696528e-04 -2.823945e-04
## ASV0382      3.355335e-38  2.013564e-04  2.109169e-04  2.208925e-04
## ASV2357      1.411664e-37  8.436719e-04  8.834541e-04  9.250672e-04
## ASV0567     -2.716272e-38 -1.626457e-04 -1.703384e-04 -1.783808e-04
## ASV0165      2.354019e-38  1.407231e-04  1.473723e-04  1.543154e-04
## ASV0005      3.483563e-38  2.067897e-04  2.164879e-04  2.266101e-04
## ASV0384     -5.354142e-39 -2.849546e-05 -2.970407e-05 -3.091708e-05
## ASV0002      6.720599e-39  3.943301e-05  4.127994e-05  4.318682e-05
## ASV3017      1.904511e-37  1.117894e-03  1.169777e-03  1.223801e-03
## ASV0091     -4.777808e-39 -2.810281e-05 -2.942548e-05 -3.078931e-05
## ASV0186     -6.984215e-38 -4.153868e-04 -4.349010e-04 -4.552776e-04
## ASV0370      3.767172e-38  2.228121e-04  2.331389e-04  2.439929e-04
## ASV0018      4.449896e-38  2.644329e-04  2.768324e-04  2.897905e-04
## ASV1377      4.584658e-37  2.697920e-03  2.823411e-03  2.954170e-03
## ASV0019      4.664424e-38  2.772830e-04  2.902663e-04  3.038576e-04
## ASV0023     -2.842536e-38 -1.704610e-04 -1.785763e-04 -1.870203e-04
## ASV2194      4.524708e-38  2.722966e-04  2.852289e-04  2.987659e-04
## ASV1155      1.928985e-37  1.130853e-03  1.184678e-03  1.239375e-03
## ASV0510     -5.361231e-38 -3.115241e-04 -3.253373e-04 -3.401732e-04
## ASV2371     -1.159767e-37 -6.806846e-04 -7.128385e-04 -7.457802e-04
## ASV0024     -3.550268e-38 -2.126955e-04 -2.227836e-04 -2.333058e-04
## ASV2452      1.193634e-37  6.957898e-04  7.277183e-04  7.610563e-04
## ASV2332     -3.302952e-37 -1.944731e-03 -2.036378e-03 -2.130801e-03
## ASV2591      7.517177e-38  4.679331e-04  4.900016e-04  5.140271e-04
## ASV0521      7.224752e-38  4.326109e-04  4.530586e-04  4.744433e-04
## ASV5542      6.885571e-38  4.136592e-04  4.328314e-04  4.533111e-04
## ASV0336     -6.841714e-39 -4.508153e-05 -4.736662e-05 -4.981735e-05
## ASV10102     1.277817e-37  7.654269e-04  8.014724e-04  8.393075e-04
## ASV16823    -2.126026e-37 -1.238139e-03 -1.296324e-03 -1.355722e-03
## ASV3104      1.100052e-36  6.406398e-03  6.706984e-03  7.014284e-03
## ASV0781      1.459523e-37  8.667192e-04  9.072450e-04  9.496789e-04
## ASV10899     7.610161e-38  4.725408e-04  4.952506e-04  5.195021e-04
## ASV11222    -3.742099e-37 -2.179294e-03 -2.281447e-03 -2.385978e-03
## ASV11327    -3.359744e-37 -1.956621e-03 -2.048190e-03 -2.142029e-03
## ASV12458    -3.742099e-37 -2.179294e-03 -2.281122e-03 -2.385628e-03
## ASV1636      2.047571e-37  1.207908e-03  1.263819e-03  1.322495e-03
## ASV1890     -1.778896e-37 -1.023608e-03 -1.071256e-03 -1.119688e-03
## ASV2898      2.744464e-37  1.618574e-03  1.693954e-03  1.772593e-03
## ASV8328      1.630693e-38  1.300952e-04  1.370880e-04  1.452445e-04
## ASV0709     -3.018119e-37 -1.789316e-03 -1.872633e-03 -1.960042e-03
## ASV0856      2.392674e-37  1.441905e-03  1.510201e-03  1.581953e-03
## ASV0909      5.978058e-38  3.800739e-04  3.991164e-04  4.191287e-04
## ASV0937     -1.730826e-37 -1.033981e-03 -1.083013e-03 -1.134025e-03
## ASV11390    -5.340841e-37 -3.110357e-03 -3.255460e-03 -3.404605e-03
## ASV11966     1.144392e-37  6.959099e-04  7.289987e-04  7.639523e-04
## ASV12990     9.064135e-38  5.343952e-04  5.588719e-04  5.847845e-04
## ASV14797     1.359248e-37  7.971642e-04  8.339242e-04  8.723911e-04
## ASV14904    -7.663994e-37 -4.463297e-03 -4.671413e-03 -4.885431e-03
## ASV15304     6.870890e-38  4.247617e-04  4.450823e-04  4.667712e-04
## ASV16696    -2.648059e-37 -1.542156e-03 -1.613973e-03 -1.687915e-03
## ASV1690      4.046539e-37  2.443585e-03  2.559658e-03  2.681510e-03
## ASV2029      2.982529e-37  1.764179e-03  1.846491e-03  1.932491e-03
## ASV2834      3.638902e-37  2.172698e-03  2.275059e-03  2.382103e-03
## ASV4003      2.850101e-37  1.731167e-03  1.813661e-03  1.900553e-03
## ASV4064      1.713067e-37  1.026027e-03  1.074330e-03  1.125036e-03
## ASV4294      9.553152e-38  5.890072e-04  6.173414e-04  6.473637e-04
## ASV4609      1.010452e-37  5.985321e-04  6.255660e-04  6.547000e-04
## ASV6283     -2.475375e-37 -1.441589e-03 -1.508756e-03 -1.577882e-03
## ASV6491     -3.547982e-37 -2.066246e-03 -2.162363e-03 -2.261430e-03
## ASV7453      1.508363e-37  9.194136e-04  9.631182e-04  1.009401e-03
## ASV7959      4.836774e-38  3.080012e-04  3.229840e-04  3.391742e-04
## ASV8219      3.066233e-36  1.785688e-02  1.868674e-02  1.954285e-02
## ASV8547     -3.176539e-37 -1.849928e-03 -1.935762e-03 -2.024441e-03
## ASV9319      1.259264e-37  7.580346e-04  7.938387e-04  8.315055e-04
## ASV9382     -6.215338e-37 -3.619639e-03 -3.787417e-03 -3.960919e-03
## ASV11516    -4.151348e-37 -2.417629e-03 -2.529513e-03 -2.645383e-03
## ASV14377    -2.997498e-37 -1.745659e-03 -1.826317e-03 -1.909970e-03
## ASV1867      2.145502e-37  1.284238e-03  1.344794e-03  1.408235e-03
## ASV1895      1.164068e-37  6.795162e-04  7.107382e-04  7.433377e-04
## ASV3168      1.438969e-37  8.448594e-04  8.839174e-04  9.247297e-04
## ASV4449      7.679383e-37  4.551731e-03  4.765102e-03  4.987610e-03
## ASV6596      1.469135e-37  8.970217e-04  9.400955e-04  9.853805e-04
## ASV7492     -4.126145e-38 -2.195226e-04 -2.288157e-04 -2.381842e-04
## ASV9854     -6.526089e-38 -3.774400e-04 -3.948614e-04 -4.128207e-04
## ASV6296      5.030017e-36  2.929341e-02  3.064401e-02  3.204754e-02
## ASV4201      1.026169e-38  8.685832e-05  9.205550e-05  9.773181e-05
## ASV0552      1.490937e-37  8.910832e-04  9.330883e-04  9.770376e-04
## ASV3671     -1.031427e-37 -6.079324e-04 -6.363295e-04 -6.658759e-04
## ASV3529     -3.652550e-38 -1.956160e-04 -2.038236e-04 -2.122475e-04
## ASV1060      3.860869e-38  2.327750e-04  2.438620e-04  2.554597e-04
## ASV0239     -5.819015e-38 -3.383358e-04 -3.539004e-04 -3.700723e-04
## ASV5711     -2.531677e-37 -1.491145e-03 -1.560504e-03 -1.632871e-03
## ASV4152     -3.481160e-37 -2.070563e-03 -2.167781e-03 -2.269375e-03
## ASV1461      1.863685e-37  1.086678e-03  1.136580e-03  1.188668e-03
## ASV2877      9.571357e-38  5.602152e-04  5.860947e-04  6.130690e-04
## ASV0012      1.577765e-38  9.374731e-05  9.815665e-05  1.027518e-04
## ASV9823      2.618292e-38  1.481888e-04  1.547834e-04  1.616280e-04
## ASV0008      1.694051e-38  1.004372e-04  1.051412e-04  1.100513e-04
## ASV7832     -2.042507e-37 -1.215887e-03 -1.272950e-03 -1.332673e-03
## ASV1915     -2.742264e-38 -1.599494e-04 -1.672642e-04 -1.749424e-04
## ASV0055     -1.641800e-38 -1.010925e-04 -1.059864e-04 -1.111361e-04
## ASV0032      9.506820e-39  5.425627e-05  5.667882e-05  5.921232e-05
## ASV2977     -2.898514e-37 -1.722051e-03 -1.802712e-03 -1.887086e-03
## ASV0466      2.465106e-37  1.437289e-03  1.503298e-03  1.572196e-03
## ASV3866      1.550424e-37  9.297521e-04  9.737214e-04  1.019752e-03
## ASV0040      5.692295e-38  3.394567e-04  3.554210e-04  3.721224e-04
## ASV0496     -7.945464e-39 -5.877123e-05 -6.206889e-05 -6.559183e-05
## ASV0052      4.771170e-38  2.847273e-04  2.981012e-04  3.121180e-04
## ASV3828     -1.786474e-37 -1.039703e-03 -1.087322e-03 -1.137072e-03
## ASV1930      8.869797e-38  5.223070e-04  5.466210e-04  5.719488e-04
## ASV2126      1.488711e-37  8.809534e-04  9.220631e-04  9.650255e-04
## ASV0793      1.763401e-37  1.056054e-03  1.105941e-03  1.158146e-03
## ASV0299     -3.419418e-39 -2.041398e-05 -2.136851e-05 -2.237839e-05
## ASV0208      1.289910e-37  7.690081e-04  8.051568e-04  8.429800e-04
## ASV0511     -5.723011e-38 -3.328807e-04 -3.481098e-04 -3.640139e-04
## ASV1123     -1.722502e-37 -1.003009e-03 -1.048982e-03 -1.096989e-03
## ASV0099      4.206423e-39  2.626790e-05  2.756051e-05  2.892067e-05
## ASV0752     -8.851137e-38 -5.345677e-04 -5.600220e-04 -5.866925e-04
## ASV0883      1.219672e-37  7.354348e-04  7.703855e-04  8.070123e-04
## ASV0683      1.611531e-37  9.679840e-04  1.013888e-03  1.061901e-03
## ASV4117     -2.629175e-37 -1.565843e-03 -1.639411e-03 -1.716355e-03
## ASV2172      1.953326e-38  1.114450e-04  1.164520e-04  1.216528e-04
## ASV0330     -4.861720e-38 -2.906564e-04 -3.043633e-04 -3.187047e-04
## ASV0728      2.444617e-37  1.453258e-03  1.521328e-03  1.592557e-03
## ASV0499      6.251727e-38  3.758752e-04  3.937051e-04  4.123694e-04
## ASV0120     -1.082089e-37 -6.436764e-04 -6.738477e-04 -7.054201e-04
## ASV1446      9.369347e-38  5.353076e-04  5.594454e-04  5.845024e-04
## ASV17171    -2.104844e-37 -1.248307e-03 -1.306675e-03 -1.367725e-03
## ASV0533      1.439625e-38  8.796235e-05  9.221258e-05  9.665868e-05
## ASV2495     -4.590535e-38 -2.831938e-04 -2.970048e-04 -3.114800e-04
## ASV5582      1.059913e-37  6.115437e-04  6.392715e-04  6.682151e-04
## ASV1488      3.822586e-38  2.248424e-04  2.352144e-04  2.460959e-04
## ASV0682      4.525921e-38  2.727429e-04  2.857058e-04  2.992824e-04
## ASV0068     -8.159729e-38 -4.860482e-04 -5.088733e-04 -5.327535e-04
## ASV1987     -1.945158e-37 -1.176091e-03 -1.232145e-03 -1.290894e-03
## ASV0035     -1.160925e-38 -7.597101e-05 -7.987604e-05 -8.399370e-05
## ASV7192     -1.300117e-37 -7.667848e-04 -8.024248e-04 -8.396821e-04
## ASV0873      5.556373e-38  1.849835e-04  1.868486e-04  1.879830e-04
## ASV4749      7.244538e-39  2.036600e-05  2.019215e-05  1.991972e-05
## ASV2174      9.567079e-38  5.541191e-04  5.793604e-04  6.057076e-04
## ASV1476     -8.748873e-38 -5.259464e-04 -5.508902e-04 -5.770109e-04
## ASV0740     -2.484042e-37 -1.494086e-03 -1.564987e-03 -1.639208e-03
## ASV0170     -5.002364e-38 -2.979915e-04 -3.119876e-04 -3.266305e-04
## ASV2466     -2.282574e-37 -1.358984e-03 -1.422773e-03 -1.489521e-03
## ASV1709      8.767156e-38  5.134136e-04  5.370921e-04  5.618503e-04
## ASV6170     -3.509325e-37 -2.102768e-03 -2.202137e-03 -2.306152e-03
## ASV3673      1.705017e-37  1.025392e-03  1.074025e-03  1.124955e-03
## ASV1745     -4.242094e-38 -2.586888e-04 -2.711346e-04 -2.841809e-04
##                                                                    
## (Intercept)  8.301571e-03  8.690993e-03  9.098390e-03  9.524565e-03
## ASV1236      1.677899e-03  1.755447e-03  1.836467e-03  1.921104e-03
## ASV0421      1.668480e-04  1.752816e-04  1.841623e-04  1.935154e-04
## ASV0691     -1.355487e-03 -1.416672e-03 -1.480457e-03 -1.546936e-03
## ASV0899      1.448726e-03  1.515870e-03  1.586036e-03  1.659352e-03
## ASV1004      3.351604e-03  3.506771e-03  3.668909e-03  3.838310e-03
## ASV1041     -1.381507e-03 -1.445396e-03 -1.512147e-03 -1.581879e-03
## ASV1058      2.094315e-03  2.191194e-03  2.292418e-03  2.398169e-03
## ASV12542     8.219628e-04  8.596917e-04  8.990848e-04  9.402090e-04
## ASV1294      1.947415e-03  2.037549e-03  2.131730e-03  2.230128e-03
## ASV13113     6.200654e-04  6.496611e-04  6.806725e-04  7.131675e-04
## ASV1318      1.942678e-03  2.032574e-03  2.126503e-03  2.224637e-03
## ASV2269     -3.369228e-03 -3.524991e-03 -3.687728e-03 -3.857732e-03
## ASV2542      1.592493e-03  1.667557e-03  1.746122e-03  1.828349e-03
## ASV2660     -1.344956e-03 -1.407007e-03 -1.471824e-03 -1.539522e-03
## ASV2737      4.760918e-04  4.977397e-04  5.203232e-04  5.438779e-04
## ASV2840      1.815140e-03  1.898245e-03  1.984993e-03  2.075529e-03
## ASV3053      9.237311e-03  9.661694e-03  1.010483e-02  1.056748e-02
## ASV3077      5.879968e-04  6.150422e-04  6.432861e-04  6.727773e-04
## ASV3134      9.986508e-04  1.046048e-03  1.095686e-03  1.147672e-03
## ASV3140      1.381905e-03  1.446649e-03  1.514374e-03  1.585214e-03
## ASV3579      4.676198e-04  4.901911e-04  5.138654e-04  5.386978e-04
## ASV6119     -9.220760e-04 -9.647007e-04 -1.009234e-03 -1.055755e-03
## ASV7557     -1.873733e-03 -1.960343e-03 -2.050830e-03 -2.145356e-03
## ASV8422      4.710377e-04  4.926869e-04  5.152939e-04  5.388975e-04
## ASV1086     -7.699646e-05 -8.042909e-05 -8.400358e-05 -8.772467e-05
## ASV1310      8.968751e-04  9.383619e-04  9.817089e-04  1.026994e-03
## ASV15750    -1.258283e-04 -1.315376e-04 -1.374920e-04 -1.437008e-04
## ASV16905    -3.853032e-04 -4.031130e-04 -4.217202e-04 -4.411579e-04
## ASV2033      1.589292e-03  1.664515e-03  1.743275e-03  1.825737e-03
## ASV2089      8.120216e-04  8.495698e-04  8.888001e-04  9.297830e-04
## ASV2127      2.636215e-03  2.758141e-03  2.885534e-03  3.018621e-03
## ASV2725      2.125545e-03  2.223348e-03  2.325487e-03  2.432139e-03
## ASV2804     -7.976039e-04 -8.344699e-04 -8.729860e-04 -9.132212e-04
## ASV3075      1.723202e-03  1.803614e-03  1.887702e-03  1.975626e-03
## ASV3327      2.352117e-03  2.462897e-03  2.578835e-03  2.700165e-03
## ASV3342      2.028752e-03  2.124065e-03  2.223795e-03  2.328139e-03
## ASV3532     -2.251955e-03 -2.357319e-03 -2.467523e-03 -2.582781e-03
## ASV3600      1.044226e-03  1.093164e-03  1.144357e-03  1.197907e-03
## ASV4013      1.968935e-03  2.060546e-03  2.156318e-03  2.256427e-03
## ASV4136      2.131895e-03  2.230038e-03  2.332539e-03  2.439576e-03
## ASV4195      8.141603e-03  8.517878e-03  8.910992e-03  9.321649e-03
## ASV4407     -3.145544e-03 -3.290908e-03 -3.442776e-03 -3.601420e-03
## ASV4717      5.632933e-04  5.888148e-04  6.154300e-04  6.431800e-04
## ASV6794      1.320844e-03  1.381313e-03  1.444434e-03  1.510313e-03
## ASV8324     -1.614045e-03 -1.688635e-03 -1.766562e-03 -1.847966e-03
## ASV8981     -4.996651e-05 -5.196024e-05 -5.401262e-05 -5.612316e-05
## ASV9859      5.212204e-04  5.465244e-04  5.730789e-04  6.009479e-04
## ASV0936      1.528148e-03  1.600001e-03  1.675187e-03  1.753857e-03
## ASV12683     1.714293e-06  1.678857e-06  1.631064e-06  1.569333e-06
## ASV1293      1.048167e-03  1.096566e-03  1.147127e-03  1.199941e-03
## ASV13055    -3.200385e-05 -3.325190e-05 -3.453340e-05 -3.584762e-05
## ASV17063    -8.373735e-04 -8.760592e-04 -9.164748e-04 -9.586924e-04
## ASV2228      6.828695e-04  7.144147e-04  7.473704e-04  7.817951e-04
## ASV2769      9.622185e-05  1.010322e-04  1.060927e-04  1.114170e-04
## ASV2803      7.510109e-04  7.853108e-04  8.211070e-04  8.584580e-04
## ASV2896      5.744400e-04  6.015025e-04  6.298266e-04  6.594699e-04
## ASV3062      6.766757e-04  7.091216e-04  7.431329e-04  7.787858e-04
## ASV3107      1.074858e-03  1.125367e-03  1.178217e-03  1.233514e-03
## ASV3265      1.501325e-03  1.570599e-03  1.642963e-03  1.718544e-03
## ASV3666      1.560353e-05  1.629269e-05  1.700939e-05  1.775439e-05
## ASV4497      5.126186e-04  5.363738e-04  5.611983e-04  5.871373e-04
## ASV6914     -7.011746e-05 -7.357941e-05 -7.721775e-05 -8.104195e-05
## ASV0576     -1.825064e-03 -1.908175e-03 -1.994888e-03 -2.085343e-03
## ASV0673      1.966663e-03  2.058055e-03  2.153586e-03  2.253433e-03
## ASV0772      9.095347e-04  9.519054e-04  9.962050e-04  1.042517e-03
## ASV0862      6.009915e-05  6.381431e-05  6.778587e-05  7.203328e-05
## ASV0898      6.884056e-04  7.210823e-04  7.553043e-04  7.911439e-04
## ASV0910      8.033070e-04  8.411359e-04  8.807261e-04  9.221575e-04
## ASV0964     -6.855565e-04 -7.169275e-04 -7.496724e-04 -7.838456e-04
## ASV10059     5.621160e-04  5.889059e-04  6.169732e-04  6.463789e-04
## ASV10263    -1.274993e-03 -1.333923e-03 -1.395490e-03 -1.459805e-03
## ASV1088      1.439707e-03  1.507242e-03  1.577899e-03  1.651815e-03
## ASV1101      1.825358e-03  1.909642e-03  1.997691e-03  2.089661e-03
## ASV1183      4.737944e-04  4.959611e-04  5.191461e-04  5.433943e-04
## ASV11956     4.772485e-04  4.989491e-04  5.215871e-04  5.451984e-04
## ASV12774     3.527923e-05  3.663838e-05  3.803210e-05  3.945925e-05
## ASV1321      2.065642e-03  2.163199e-03  2.265325e-03  2.372229e-03
## ASV13793    -8.791040e-04 -9.197345e-04 -9.621835e-04 -1.006527e-03
## ASV14482     5.928580e-05  6.191135e-05  6.464388e-05  6.748689e-05
## ASV15483     3.526652e-04  3.692614e-04  3.866291e-04  4.048032e-04
## ASV2062      1.672020e-03  1.749735e-03  1.830971e-03  1.915879e-03
## ASV2132      1.344062e-03  1.407241e-03  1.473349e-03  1.542519e-03
## ASV2413      1.301480e-03  1.361681e-03  1.424582e-03  1.490296e-03
## ASV2490      4.050642e-03  4.236551e-03  4.430657e-03  4.633291e-03
## ASV2594      4.927999e-04  5.158531e-04  5.399656e-04  5.651844e-04
## ASV2822     -2.319689e-03 -2.426919e-03 -2.538949e-03 -2.655982e-03
## ASV2863      2.480970e-03  2.595202e-03  2.714508e-03  2.839095e-03
## ASV2910      9.042481e-04  9.460089e-04  9.896360e-04  1.035207e-03
## ASV2980      9.983319e-04  1.044790e-03  1.093358e-03  1.144127e-03
## ASV3307      1.845788e-03  1.931098e-03  2.020225e-03  2.113331e-03
## ASV3474      1.176672e-03  1.232454e-03  1.290868e-03  1.352037e-03
## ASV3502      1.261066e-03  1.319997e-03  1.381628e-03  1.446079e-03
## ASV4236      1.909509e-03  1.996997e-03  2.088328e-03  2.183655e-03
## ASV4842     -1.951028e-04 -2.043867e-04 -2.141107e-04 -2.242953e-04
## ASV4894     -8.791979e-04 -9.198377e-04 -9.622969e-04 -1.006652e-03
## ASV5290      6.832169e-04  7.152947e-04  7.488565e-04  7.839688e-04
## ASV5501      4.207898e-04  4.404331e-04  4.609751e-04  4.824552e-04
## ASV5795      4.584045e-04  4.799496e-04  5.024935e-04  5.260814e-04
## ASV5987     -2.455650e-03 -2.569167e-03 -2.687766e-03 -2.811662e-03
## ASV6267     -2.766984e-03 -2.894882e-03 -3.028507e-03 -3.168096e-03
## ASV6862      1.121417e-03  1.172893e-03  1.226641e-03  1.282751e-03
## ASV7145      4.997413e-04  5.225186e-04  5.462862e-04  5.710826e-04
## ASV7673     -8.791707e-04 -9.198080e-04 -9.622645e-04 -1.006616e-03
## ASV7789      4.080752e-04  4.278245e-04  4.485439e-04  4.702822e-04
## ASV7809      1.892925e-05  2.015151e-05  2.146179e-05  2.286698e-05
## ASV8002     -1.110358e-03 -1.161680e-03 -1.215300e-03 -1.271313e-03
## ASV8205      4.558090e-04  4.771708e-04  4.995173e-04  5.228925e-04
## ASV9155     -2.852844e-04 -2.983754e-04 -3.120433e-04 -3.263113e-04
## ASV9221      9.520716e-05  1.002087e-04  1.054922e-04  1.110751e-04
## ASV9311     -1.781221e-03 -1.863547e-03 -1.949558e-03 -2.039408e-03
## ASV9557     -1.217313e-03 -1.273571e-03 -1.332347e-03 -1.393746e-03
## ASV9936     -2.454841e-03 -2.568282e-03 -2.686800e-03 -2.810605e-03
## ASV1445      1.460472e-03  1.528955e-03  1.600599e-03  1.675543e-03
## ASV4232      5.399460e-04  5.656615e-04  5.926022e-04  6.208265e-04
## ASV6479      1.739644e-04  1.828642e-04  1.922452e-04  2.021353e-04
## ASV0142     -1.062162e-03 -1.111121e-03 -1.162258e-03 -1.215664e-03
## ASV0378      4.595680e-04  4.814759e-04  5.044290e-04  5.284772e-04
## ASV1122      1.408548e-03  1.474758e-03  1.544038e-03  1.616527e-03
## ASV0123     -9.388763e-04 -9.821237e-04 -1.027293e-03 -1.074463e-03
## ASV2064      4.905549e-04  5.128377e-04  5.360803e-04  5.603191e-04
## ASV4459     -7.187421e-05 -7.503529e-05 -7.832275e-05 -8.174044e-05
## ASV0448      3.671641e-04  3.846792e-04  4.030310e-04  4.222593e-04
## ASV0397      8.376788e-04  8.767469e-04  9.175977e-04  9.603089e-04
## ASV0485      9.803331e-04  1.025835e-03  1.073393e-03  1.123094e-03
## ASV1566      1.436107e-03  1.503027e-03  1.572996e-03  1.646144e-03
## ASV1365      1.218627e-03  1.275664e-03  1.335323e-03  1.397719e-03
## ASV1065      1.734410e-03  1.815498e-03  1.900304e-03  1.988994e-03
## ASV0722     -8.878193e-05 -9.298512e-05 -9.738626e-05 -1.019946e-04
## ASV12660    -1.020145e-03 -1.067042e-03 -1.116015e-03 -1.167148e-03
## ASV0223      2.702904e-04  2.828501e-04  2.959787e-04  3.097008e-04
## ASV0229      4.052476e-04  4.243059e-04  4.442492e-04  4.651175e-04
## ASV0877      1.798192e-04  1.879778e-04  1.964863e-04  2.053575e-04
## ASV0983      9.757436e-04  1.020955e-03  1.068201e-03  1.117568e-03
## ASV0626      8.519757e-05  8.977576e-05  9.462018e-05  9.974784e-05
## ASV4146      4.792089e-05  5.015610e-05  5.249252e-05  5.493436e-05
## ASV4175     -1.178921e-03 -1.234284e-03 -1.292209e-03 -1.352812e-03
## ASV2082     -4.945172e-04 -5.188640e-04 -5.444455e-04 -5.713274e-04
## ASV2272      5.631855e-04  5.895690e-04  6.171681e-04  6.460368e-04
## ASV2245     -8.393434e-04 -8.788444e-04 -9.201817e-04 -9.634384e-04
## ASV0590     -4.554364e-04 -4.782376e-04 -5.022287e-04 -5.274757e-04
## ASV0217      1.724989e-05  1.890435e-05  2.071523e-05  2.269700e-05
## ASV0416      6.762066e-04  7.067968e-04  7.386928e-04  7.719428e-04
## ASV1056      8.050423e-04  8.431387e-04  8.830259e-04  9.247867e-04
## ASV7777     -1.151300e-03 -1.205236e-03 -1.261655e-03 -1.320670e-03
## ASV0455      2.074659e-04  2.171607e-04  2.272996e-04  2.379022e-04
## ASV0604      5.262144e-04  5.512372e-04  5.774476e-04  6.049017e-04
## ASV6100     -7.878001e-04 -8.248782e-04 -8.636808e-04 -9.042862e-04
## ASV11359    -1.704619e-03 -1.784514e-03 -1.868092e-03 -1.955517e-03
## ASV6604      2.320782e-04  2.430922e-04  2.546268e-04  2.667066e-04
## ASV5004     -6.090616e-04 -6.375166e-04 -6.672750e-04 -6.983942e-04
## ASV1483     -2.632744e-04 -2.755474e-04 -2.883799e-04 -3.017961e-04
## ASV9773     -7.657274e-04 -8.016786e-04 -8.392935e-04 -8.786465e-04
## ASV4059     -1.850781e-05 -1.873680e-05 -1.891574e-05 -1.903668e-05
## ASV1193      9.337816e-04  9.773567e-04  1.022922e-03  1.070566e-03
## ASV4610     -1.755059e-04 -1.827750e-04 -1.902902e-04 -1.980540e-04
## ASV0742     -1.117961e-04 -1.162743e-04 -1.208870e-04 -1.256335e-04
## ASV1502     -2.746038e-05 -2.920483e-05 -3.107314e-05 -3.307492e-05
## ASV0195      3.158219e-05  3.276593e-05  3.397646e-05  3.521240e-05
## ASV1213      6.805403e-04  7.115755e-04  7.439602e-04  7.777468e-04
## ASV1648     -7.083737e-04 -7.416849e-04 -7.765429e-04 -8.130176e-04
## ASV6984     -6.624295e-04 -6.935894e-04 -7.261971e-04 -7.603183e-04
## ASV0396     -4.797821e-05 -4.989295e-05 -5.186465e-05 -5.389297e-05
## ASV4297      9.775618e-04  1.022444e-03  1.069306e-03  1.118228e-03
## ASV2622      1.499993e-03  1.569365e-03  1.641847e-03  1.717569e-03
## ASV3512      5.463058e-04  5.727468e-04  6.004870e-04  6.295919e-04
## ASV2411      9.869559e-04  1.033704e-03  1.082654e-03  1.133909e-03
## ASV2291     -3.887378e-04 -4.083782e-04 -4.290589e-04 -4.508390e-04
## ASV0807      1.374821e-03  1.438993e-03  1.506099e-03  1.576266e-03
## ASV1292      3.477000e-04  3.634215e-04  3.798137e-04  3.969012e-04
## ASV1035      1.284676e-03  1.343853e-03  1.405661e-03  1.470210e-03
## ASV0070      1.495790e-06  1.864277e-06  2.278292e-06  2.742581e-06
## ASV0255      1.246108e-04  1.302654e-04  1.361628e-04  1.423123e-04
## ASV0057     -3.584258e-04 -3.747867e-04 -3.918601e-04 -4.096739e-04
## ASV0077     -7.959570e-05 -8.311827e-05 -8.678343e-05 -9.059567e-05
## ASV0625      7.426074e-04  7.767341e-04  8.123699e-04  8.495758e-04
## ASV2464      5.068327e-03  5.300654e-03  5.543206e-03  5.796391e-03
## ASV1315      1.282202e-03  1.343058e-03  1.406791e-03  1.473538e-03
## ASV2673      1.098916e-03  1.151102e-03  1.205760e-03  1.263004e-03
## ASV2161      4.657163e-04  4.877966e-04  5.109191e-04  5.351326e-04
## ASV0337     -2.699682e-04 -2.826604e-04 -2.959415e-04 -3.098379e-04
## ASV7680     -1.759088e-03 -1.841875e-03 -1.928510e-03 -2.019169e-03
## ASV0611      9.817116e-04  1.027935e-03  1.076309e-03  1.126933e-03
## ASV3118     -1.004135e-03 -1.051924e-03 -1.101985e-03 -1.154426e-03
## ASV1284      4.288515e-04  4.468907e-04  4.655656e-04  4.848860e-04
## ASV0889      7.592570e-04  7.944441e-04  8.312160e-04  8.696397e-04
## ASV4649     -3.752951e-04 -3.928579e-04 -4.112278e-04 -4.304406e-04
## ASV1108     -7.456424e-04 -7.813128e-04 -8.186970e-04 -8.578778e-04
## ASV0738      3.984376e-04  4.179600e-04  4.384634e-04  4.599992e-04
## ASV0473     -7.511292e-05 -7.900937e-05 -8.312049e-05 -8.745906e-05
## ASV0598     -1.987660e-04 -2.086710e-04 -2.190891e-04 -2.300487e-04
## ASV0429      5.678454e-04  5.940287e-04  6.213778e-04  6.499405e-04
## ASV1549      1.013112e-03  1.061251e-03  1.111673e-03  1.164484e-03
## ASV1203      8.236281e-04  8.618760e-04  9.018533e-04  9.436340e-04
## ASV4532      3.968088e-05  4.137597e-05  4.313398e-05  4.495634e-05
## ASV0274      1.355758e-04  1.421407e-04  1.490280e-04  1.562540e-04
## ASV0163     -6.466617e-04 -6.763271e-04 -7.072995e-04 -7.396314e-04
## ASV1298      7.486872e-05  7.815824e-05  8.157925e-05  8.513578e-05
## ASV9424     -1.360289e-03 -1.424415e-03 -1.491534e-03 -1.561782e-03
## ASV0412      1.433986e-03  1.500396e-03  1.569792e-03  1.642301e-03
## ASV0284      3.133943e-04  3.274477e-04  3.420888e-04  3.573382e-04
## ASV0620     -2.722679e-04 -2.856216e-04 -2.996472e-04 -3.143801e-04
## ASV0153     -1.354584e-03 -1.418950e-03 -1.486368e-03 -1.556980e-03
## ASV0498      4.836094e-04  5.063955e-04  5.302431e-04  5.552004e-04
## ASV0097      2.662307e-04  2.788750e-04  2.921182e-04  3.059885e-04
## ASV0104     -1.931449e-03 -2.021446e-03 -2.115541e-03 -2.213912e-03
## ASV1282      6.770957e-04  7.082703e-04  7.408284e-04  7.748262e-04
## ASV3883     -5.057419e-04 -5.301450e-04 -5.557393e-04 -5.825841e-04
## ASV0801      2.581840e-04  2.703389e-04  2.830592e-04  2.963703e-04
## ASV1611     -1.213287e-03 -1.270706e-03 -1.330825e-03 -1.393769e-03
## ASV0227     -2.042853e-04 -2.144810e-04 -2.252055e-04 -2.364878e-04
## ASV0833      4.165167e-04  4.360930e-04  4.565767e-04  4.780087e-04
## ASV0718      1.868418e-03  1.956035e-03  2.047695e-03  2.143581e-03
## ASV1139      2.639387e-04  2.755135e-04  2.875461e-04  3.000496e-04
## ASV0766     -2.509301e-04 -2.630609e-04 -2.757857e-04 -2.891342e-04
## ASV2091      1.558500e-03  1.630160e-03  1.704993e-03  1.783126e-03
## ASV1238     -1.378498e-03 -1.443511e-03 -1.511560e-03 -1.582785e-03
## ASV9193     -1.139840e-04 -1.200026e-04 -1.263634e-04 -1.330879e-04
## ASV0290      2.123471e-04  2.217954e-04  2.316318e-04  2.418694e-04
## ASV0231      5.644681e-04  5.906127e-04  6.179331e-04  6.464787e-04
## ASV0185      3.065003e-04  3.214886e-04  3.372274e-04  3.537558e-04
## ASV2330      6.582021e-04  6.882957e-04  7.197049e-04  7.524815e-04
## ASV3119     -2.785499e-04 -2.921356e-04 -3.063981e-04 -3.213725e-04
## ASV2368     -7.002598e-04 -7.335433e-04 -7.684062e-04 -8.049230e-04
## ASV0122     -3.491884e-04 -3.654188e-04 -3.823847e-04 -4.001174e-04
## ASV1044      8.739917e-04  9.153593e-04  9.586727e-04  1.004022e-03
## ASV0160     -3.827994e-04 -4.003125e-04 -4.185924e-04 -4.376694e-04
## ASV0326      9.750052e-05  1.020902e-04  1.068933e-04  1.119193e-04
## ASV1388      1.807665e-03  1.891829e-03  1.979819e-03  2.071800e-03
## ASV0792      1.356358e-03  1.418976e-03  1.484390e-03  1.552716e-03
## ASV0036     -4.061160e-04 -4.254237e-04 -4.456473e-04 -4.668300e-04
## ASV2125      1.288241e-03  1.348359e-03  1.411224e-03  1.476955e-03
## ASV1075     -1.947045e-05 -2.037334e-05 -2.131714e-05 -2.230365e-05
## ASV0390      6.712021e-04  7.030830e-04  7.364743e-04  7.714472e-04
## ASV3790     -9.657192e-04 -1.011145e-03 -1.058681e-03 -1.108422e-03
## ASV1535     -2.666695e-04 -2.796310e-04 -2.932341e-04 -3.075118e-04
## ASV0263      1.190547e-03  1.246275e-03  1.304566e-03  1.365532e-03
## ASV0675      1.769255e-03  1.852763e-03  1.940176e-03  2.031674e-03
## ASV3348      1.396208e-04  1.463460e-04  1.533983e-04  1.607941e-04
## ASV0058     -5.354625e-04 -5.603645e-04 -5.863958e-04 -6.136050e-04
## ASV4142      7.591955e-04  7.942308e-04  8.308283e-04  8.690526e-04
## ASV0059     -4.327884e-04 -4.528652e-04 -4.738478e-04 -4.957747e-04
## ASV0013     -7.607525e-04 -7.963398e-04 -8.335610e-04 -8.724884e-04
## ASV0033     -3.536846e-04 -3.704752e-04 -3.880602e-04 -4.064767e-04
## ASV4354     -4.480561e-04 -4.690086e-04 -4.909232e-04 -5.138426e-04
## ASV0022     -2.988524e-04 -3.130330e-04 -3.278838e-04 -3.434363e-04
## ASV0134     -2.794035e-04 -2.928325e-04 -3.069124e-04 -3.216751e-04
## ASV0415      4.153173e-05  4.365443e-05  4.589135e-05  4.824907e-05
## ASV10103    -1.671292e-03 -1.750191e-03 -1.832782e-03 -1.919234e-03
## ASV1613      1.285004e-03  1.344364e-03  1.406378e-03  1.471156e-03
## ASV0135     -1.679742e-04 -1.756390e-04 -1.836374e-04 -1.919822e-04
## ASV0469     -1.648234e-03 -1.724709e-03 -1.804637e-03 -1.888163e-03
## ASV0471      9.935132e-04  1.039943e-03  1.088501e-03  1.139280e-03
## ASV0451     -1.460559e-04 -1.534434e-04 -1.612229e-04 -1.694167e-04
## ASV0747      5.615896e-04  5.879648e-04  6.155609e-04  6.444328e-04
## ASV1314     -5.538089e-04 -5.801587e-04 -6.077611e-04 -6.366756e-04
## ASV0425     -2.060655e-03 -2.155595e-03 -2.254756e-03 -2.358311e-03
## ASV0559     -5.015963e-04 -5.249649e-04 -5.493983e-04 -5.749428e-04
## ASV0148     -1.241670e-04 -1.296017e-04 -1.352501e-04 -1.411182e-04
## ASV0129      9.561099e-05  1.007876e-04  1.062694e-04  1.120764e-04
## ASV1072      1.411646e-04  1.475255e-04  1.541550e-04  1.610630e-04
## ASV2390      1.065401e-03  1.114181e-03  1.165099e-03  1.218240e-03
## ASV0548      6.846942e-04  7.166568e-04  7.500807e-04  7.850296e-04
## ASV0168     -3.547425e-04 -3.711925e-04 -3.883840e-04 -4.063486e-04
## ASV0066     -3.979093e-04 -4.164220e-04 -4.357748e-04 -4.560041e-04
## ASV0468     -2.086446e-04 -2.184196e-04 -2.286449e-04 -2.393406e-04
## ASV0172     -1.252041e-04 -1.308309e-04 -1.366940e-04 -1.428017e-04
## ASV0236     -4.943609e-05 -5.083203e-05 -5.220460e-05 -5.354443e-05
## ASV0250      5.328918e-04  5.586192e-04  5.856047e-04  6.139112e-04
## ASV0338      2.581662e-04  2.704535e-04  2.833245e-04  2.968067e-04
## ASV0450     -4.333452e-05 -4.556730e-05 -4.792215e-05 -5.040630e-05
## ASV0377      4.979499e-04  5.210854e-04  5.452682e-04  5.705431e-04
## ASV1022     -2.199809e-05 -2.299665e-05 -2.403786e-05 -2.512328e-05
## ASV6174     -8.060284e-06 -8.524194e-06 -9.018097e-06 -9.544198e-06
## ASV0786     -5.704847e-05 -6.011776e-05 -6.336562e-05 -6.680344e-05
## ASV0053     -5.322774e-04 -5.572236e-04 -5.833195e-04 -6.106165e-04
## ASV0697     -3.305844e-04 -3.458424e-04 -3.617817e-04 -3.784303e-04
## ASV0785      6.894900e-04  7.215347e-04  7.550309e-04  7.900408e-04
## ASV1967     -6.883678e-04 -7.202381e-04 -7.535412e-04 -7.883377e-04
## ASV0385      2.221174e-04  2.327272e-04  2.438448e-04  2.554946e-04
## ASV0295      3.207547e-05  3.385656e-05  3.574632e-05  3.775212e-05
## ASV0072     -5.393724e-04 -5.643225e-04 -5.903911e-04 -6.176252e-04
## ASV0157     -8.022816e-05 -8.356298e-05 -8.701079e-05 -9.057272e-05
## ASV0501      1.147304e-03  1.201141e-03  1.257465e-03  1.316389e-03
## ASV10729    -1.436955e-03 -1.504550e-03 -1.575283e-03 -1.649299e-03
## ASV1470      7.633158e-04  7.981759e-04  8.345560e-04  8.725156e-04
## ASV0050     -1.259283e-03 -1.317875e-03 -1.379128e-03 -1.443154e-03
## ASV0411     -2.770695e-04 -2.901998e-04 -3.039491e-04 -3.183462e-04
## ASV0549      4.480193e-04  4.691599e-04  4.912886e-04  5.144508e-04
## ASV0184      1.527666e-04  1.598692e-04  1.672940e-04  1.750550e-04
## ASV0705      3.045599e-04  3.186477e-04  3.333671e-04  3.487445e-04
## ASV1715      6.331264e-04  6.627797e-04  6.937980e-04  7.262419e-04
## ASV0603      9.724035e-05  1.018385e-04  1.066529e-04  1.116935e-04
## ASV0826      1.075910e-03  1.126064e-03  1.178504e-03  1.233329e-03
## ASV0034     -3.479271e-04 -3.640363e-04 -3.808692e-04 -3.984563e-04
## ASV0838      2.655819e-04  2.770408e-04  2.889328e-04  3.012681e-04
## ASV0614     -2.949073e-04 -3.086419e-04 -3.230015e-04 -3.380132e-04
## ASV0014     -7.791543e-04 -8.155278e-04 -8.535643e-04 -8.933366e-04
## ASV0585      1.088923e-04  1.132203e-04  1.176742e-04  1.222526e-04
## ASV0016     -8.139544e-04 -8.519519e-04 -8.916865e-04 -9.332344e-04
## ASV5394     -6.057433e-04 -6.341709e-04 -6.639126e-04 -6.950271e-04
## ASV0666      1.353272e-03  1.415706e-03  1.480924e-03  1.549041e-03
## ASV2085      3.444301e-04  3.592429e-04  3.746126e-04  3.905520e-04
## ASV0003     -5.553211e-04 -5.812350e-04 -6.083327e-04 -6.366659e-04
## ASV0346      2.713066e-04  2.842317e-04  2.977722e-04  3.119575e-04
## ASV0267     -9.814350e-06 -1.002610e-05 -1.022381e-05 -1.040455e-05
## ASV0353      4.352868e-04  4.558815e-04  4.774440e-04  5.000192e-04
## ASV2419      1.200926e-03  1.256782e-03  1.315171e-03  1.376204e-03
## ASV0447      6.368663e-04  6.670464e-04  6.986492e-04  7.317409e-04
## ASV0654      9.627250e-04  1.007703e-03  1.054741e-03  1.103929e-03
## ASV0151      1.194635e-04  1.253384e-04  1.315105e-04  1.379958e-04
## ASV0065     -3.747070e-04 -3.921419e-04 -4.103685e-04 -4.294208e-04
## ASV0527      9.186209e-04  9.614523e-04  1.006237e-03  1.053060e-03
## ASV4055     -1.385603e-04 -1.452349e-04 -1.522348e-04 -1.595763e-04
## ASV0166     -4.684480e-04 -4.900610e-04 -5.126377e-04 -5.362181e-04
## ASV0417     -1.961738e-04 -2.050789e-04 -2.143670e-04 -2.240527e-04
## ASV0078     -2.763479e-04 -2.891402e-04 -3.025070e-04 -3.164722e-04
## ASV0322     -5.680309e-05 -5.924092e-05 -6.176897e-05 -6.438905e-05
## ASV0156     -6.425812e-04 -6.728004e-04 -7.044228e-04 -7.375119e-04
## ASV0648     -1.391005e-03 -1.456571e-03 -1.525196e-03 -1.597019e-03
## ASV0407     -1.027118e-04 -1.076047e-04 -1.127308e-04 -1.181011e-04
## ASV2030     -2.380289e-04 -2.490190e-04 -2.605017e-04 -2.724976e-04
## ASV0300      1.636840e-04  1.714782e-04  1.796433e-04  1.881970e-04
## ASV1150      3.462869e-05  3.635139e-05  3.816291e-05  4.006808e-05
## ASV0958      5.052090e-04  5.292783e-04  5.544947e-04  5.809129e-04
## ASV0216     -5.807225e-04 -6.076570e-04 -6.358070e-04 -6.652241e-04
## ASV0446      8.569114e-04  8.973178e-04  9.396098e-04  9.838736e-04
## ASV0367     -5.654115e-04 -5.919378e-04 -6.196894e-04 -6.487213e-04
## ASV0200     -3.366150e-04 -3.523990e-04 -3.689113e-04 -3.861844e-04
## ASV0334     -1.970351e-04 -2.057907e-04 -2.149048e-04 -2.243892e-04
## ASV1311      2.330719e-04  2.436048e-04  2.545861e-04  2.660322e-04
## ASV0458      3.472231e-04  3.628188e-04  3.790697e-04  3.959991e-04
## ASV1371      5.039140e-05  5.284470e-05  5.541961e-05  5.812233e-05
## ASV0418      7.697709e-04  8.052054e-04  8.422127e-04  8.808571e-04
## ASV0004      1.119504e-04  1.170925e-04  1.224618e-04  1.280674e-04
## ASV1943      2.232515e-03  2.332076e-03  2.435756e-03  2.543698e-03
## ASV1495     -1.293953e-04 -1.361528e-04 -1.432880e-04 -1.508239e-04
## ASV0901     -6.285070e-04 -6.582076e-04 -6.893010e-04 -7.218515e-04
## ASV0628      3.514472e-04  3.674758e-04  3.842011e-04  4.016500e-04
## ASV0400      2.097910e-04  2.194881e-04  2.296192e-04  2.402022e-04
## ASV0116     -1.850666e-04 -1.938045e-04 -2.029514e-04 -2.125260e-04
## ASV0788      1.633363e-03  1.710564e-03  1.791387e-03  1.875999e-03
## ASV0117      1.181914e-04  1.238513e-04  1.297835e-04  1.360013e-04
## ASV3137     -3.945820e-05 -4.128204e-05 -4.318755e-05 -4.517813e-05
## ASV0001      1.205752e-04  1.261017e-04  1.318711e-04  1.378932e-04
## ASV1651      3.417196e-04  3.574410e-04  3.738591e-04  3.910026e-04
## ASV1692      1.361705e-03  1.426023e-03  1.493354e-03  1.563836e-03
## ASV0660      5.137240e-04  5.370607e-04  5.614023e-04  5.867870e-04
## ASV0508      2.619495e-05  2.737008e-05  2.859446e-05  2.986982e-05
## ASV1660     -2.648101e-04 -2.776482e-04 -2.911184e-04 -3.052524e-04
## ASV0233      4.252519e-04  4.451803e-04  4.660273e-04  4.878337e-04
## ASV1343     -7.769589e-04 -8.136072e-04 -8.519674e-04 -8.921181e-04
## ASV0209      4.027732e-04  4.212498e-04  4.405401e-04  4.606768e-04
## ASV0193     -4.682757e-04 -4.898219e-04 -5.123233e-04 -5.358187e-04
## ASV0357      1.639462e-04  1.719968e-04  1.804538e-04  1.893387e-04
## ASV0198      3.510105e-04  3.673091e-04  3.843447e-04  4.021486e-04
## ASV0007      1.073460e-04  1.122370e-04  1.173401e-04  1.226635e-04
## ASV1772     -1.614067e-04 -1.687169e-04 -1.763390e-04 -1.842845e-04
## ASV0009      8.949844e-05  9.355015e-05  9.777510e-05  1.021797e-04
## ASV0006     -9.080197e-05 -9.513942e-05 -9.968464e-05 -1.044476e-04
## ASV0011     -3.212396e-04 -3.363662e-04 -3.521967e-04 -3.687634e-04
## ASV0015      6.765923e-05  7.072214e-05  7.391596e-05  7.724557e-05
## ASV0017      7.618138e-05  7.963096e-05  8.322811e-05  8.697832e-05
## ASV0235     -2.957335e-04 -3.096972e-04 -3.243144e-04 -3.396149e-04
## ASV0382      2.313368e-04  2.422709e-04  2.537173e-04  2.656995e-04
## ASV2357      9.686186e-04  1.014197e-03  1.061893e-03  1.111804e-03
## ASV0567     -1.868002e-04 -1.956137e-04 -2.048394e-04 -2.144963e-04
## ASV0165      1.615824e-04  1.691877e-04  1.771466e-04  1.854752e-04
## ASV0005      2.371963e-04  2.482672e-04  2.598439e-04  2.719486e-04
## ASV0384     -3.216869e-05 -3.345907e-05 -3.478813e-05 -3.615559e-05
## ASV0002      4.517896e-05  4.725994e-05  4.943346e-05  5.170331e-05
## ASV3017      1.280235e-03  1.339183e-03  1.400748e-03  1.465037e-03
## ASV0091     -3.221452e-05 -3.370385e-05 -3.526001e-05 -3.688581e-05
## ASV0186     -4.765925e-04 -4.988876e-04 -5.222063e-04 -5.465939e-04
## ASV0370      2.553382e-04  2.671977e-04  2.795936e-04  2.925487e-04
## ASV0018      3.033439e-04  3.175194e-04  3.323443e-04  3.478471e-04
## ASV1377      3.090808e-03  3.233572e-03  3.382718e-03  3.538512e-03
## ASV0019      3.180738e-04  3.329428e-04  3.484936e-04  3.647561e-04
## ASV0023     -1.958610e-04 -2.051165e-04 -2.148058e-04 -2.249489e-04
## ASV2194      3.129435e-04  3.277916e-04  3.433418e-04  3.596269e-04
## ASV1155      1.296554e-03  1.356284e-03  1.418673e-03  1.483830e-03
## ASV0510     -3.556404e-04 -3.717751e-04 -3.886023e-04 -4.061480e-04
## ASV2371     -7.802117e-04 -8.161818e-04 -8.537548e-04 -8.929971e-04
## ASV0024     -2.443210e-04 -2.558516e-04 -2.679214e-04 -2.805550e-04
## ASV2452      7.958546e-04  8.321738e-04  8.700737e-04  9.096159e-04
## ASV2332     -2.229512e-03 -2.332667e-03 -2.440453e-03 -2.553066e-03
## ASV2591      5.392359e-04  5.657105e-04  5.935164e-04  6.227228e-04
## ASV0521      4.968282e-04  5.202594e-04  5.447846e-04  5.704540e-04
## ASV5542      4.747422e-04  4.971779e-04  5.206644e-04  5.452497e-04
## ASV0336     -5.240307e-05 -5.513169e-05 -5.801182e-05 -6.105261e-05
## ASV10102     8.789102e-04  9.203634e-04  9.637519e-04  1.009164e-03
## ASV16823    -1.417759e-03 -1.482515e-03 -1.550101e-03 -1.620626e-03
## ASV3104      7.335229e-03  7.670242e-03  8.019884e-03  8.384734e-03
## ASV0781      9.940573e-04  1.040469e-03  1.089003e-03  1.139752e-03
## ASV10899     5.449618e-04  5.717004e-04  5.997845e-04  6.292848e-04
## ASV11222    -2.495145e-03 -2.609098e-03 -2.728027e-03 -2.852127e-03
## ASV11327    -2.240028e-03 -2.342322e-03 -2.449081e-03 -2.560482e-03
## ASV12458    -2.494763e-03 -2.608680e-03 -2.727570e-03 -2.851628e-03
## ASV1636      1.383811e-03  1.447888e-03  1.514846e-03  1.584803e-03
## ASV1890     -1.170212e-03 -1.222883e-03 -1.277781e-03 -1.334986e-03
## ASV2898      1.854785e-03  1.940682e-03  2.030441e-03  2.124223e-03
## ASV8328      1.539283e-04  1.631894e-04  1.730700e-04  1.836155e-04
## ASV0709     -2.051437e-03 -2.146999e-03 -2.246908e-03 -2.351354e-03
## ASV0856      1.657099e-03  1.735804e-03  1.818236e-03  1.904569e-03
## ASV0909      4.401909e-04  4.623591e-04  4.856954e-04  5.102656e-04
## ASV0937     -1.187418e-03 -1.243298e-03 -1.301777e-03 -1.362974e-03
## ASV11390    -3.560344e-03 -3.722907e-03 -3.892564e-03 -4.069596e-03
## ASV11966     8.005860e-04  8.389863e-04  8.792390e-04  9.214340e-04
## ASV12990     6.118550e-04  6.401401e-04  6.696906e-04  7.005591e-04
## ASV14797     9.125693e-04  9.545321e-04  9.983526e-04  1.044106e-03
## ASV14904    -5.108904e-03 -5.342167e-03 -5.585611e-03 -5.839636e-03
## ASV15304     4.895329e-04  5.134268e-04  5.385109e-04  5.648462e-04
## ASV16696    -1.765120e-03 -1.845707e-03 -1.929811e-03 -2.017571e-03
## ASV1690      2.809146e-03  2.942848e-03  3.082902e-03  3.229608e-03
## ASV2029      2.022404e-03  2.116399e-03  2.214653e-03  2.317348e-03
## ASV2834      2.494122e-03  2.611341e-03  2.733994e-03  2.862327e-03
## ASV4003      1.991625e-03  2.087086e-03  2.187148e-03  2.292038e-03
## ASV4064      1.178111e-03  1.233665e-03  1.291811e-03  1.352668e-03
## ASV4294      6.788699e-04  7.119388e-04  7.466505e-04  7.830891e-04
## ASV4609      6.851466e-04  7.169731e-04  7.502383e-04  7.850037e-04
## ASV6283     -1.650057e-03 -1.725393e-03 -1.804018e-03 -1.886060e-03
## ASV6491     -2.364863e-03 -2.472828e-03 -2.585503e-03 -2.703074e-03
## ASV7453      1.057921e-03  1.108791e-03  1.162127e-03  1.218050e-03
## ASV7959      3.562068e-04  3.741315e-04  3.929978e-04  4.128584e-04
## ASV8219      2.043667e-02  2.136963e-02  2.234330e-02  2.335928e-02
## ASV8547     -2.117025e-03 -2.213662e-03 -2.314516e-03 -2.419751e-03
## ASV9319      8.709508e-04  9.122592e-04  9.555177e-04  1.000817e-03
## ASV9382     -4.142054e-03 -4.331121e-03 -4.528435e-03 -4.734320e-03
## ASV11516    -2.766349e-03 -2.892611e-03 -3.024379e-03 -3.161870e-03
## ASV14377    -1.997301e-03 -2.088454e-03 -2.183583e-03 -2.282842e-03
## ASV1867      1.474639e-03  1.544142e-03  1.616886e-03  1.693019e-03
## ASV1895      7.773706e-04  8.128941e-04  8.499671e-04  8.886500e-04
## ASV3168      9.673626e-04  1.011892e-03  1.058396e-03  1.106954e-03
## ASV4449      5.220303e-03  5.463629e-03  5.718051e-03  5.984054e-03
## ASV6596      1.032870e-03  1.082673e-03  1.134904e-03  1.189685e-03
## ASV7492     -2.478579e-04 -2.578382e-04 -2.681259e-04 -2.787205e-04
## ASV9854     -4.315582e-04 -4.511036e-04 -4.714880e-04 -4.927431e-04
## ASV6296      3.351272e-02  3.504204e-02  3.663802e-02  3.830329e-02
## ASV4201      1.037986e-04  1.102851e-04  1.172231e-04  1.246469e-04
## ASV0552      1.023034e-03  1.071169e-03  1.121542e-03  1.174252e-03
## ASV3671     -6.967598e-04 -7.290388e-04 -7.627727e-04 -7.980235e-04
## ASV3529     -2.209543e-04 -2.299474e-04 -2.392290e-04 -2.488008e-04
## ASV1060      2.676085e-04  2.803343e-04  2.936647e-04  3.076282e-04
## ASV0239     -3.869501e-04 -4.045618e-04 -4.229359e-04 -4.421017e-04
## ASV5711     -1.708501e-03 -1.787535e-03 -1.870118e-03 -1.956397e-03
## ASV4152     -2.375652e-03 -2.486823e-03 -2.603104e-03 -2.724722e-03
## ASV1461      1.243043e-03  1.299799e-03  1.359028e-03  1.420827e-03
## ASV2877      6.412393e-04  6.706541e-04  7.013638e-04  7.334203e-04
## ASV0012      1.075583e-04  1.125855e-04  1.178431e-04  1.233415e-04
## ASV9823      1.687485e-04  1.761535e-04  1.838513e-04  1.918504e-04
## ASV0008      1.151861e-04  1.205555e-04  1.261697e-04  1.320394e-04
## ASV7832     -1.395156e-03 -1.460524e-03 -1.528907e-03 -1.600440e-03
## ASV1915     -1.829600e-04 -1.913313e-04 -2.000705e-04 -2.091927e-04
## ASV0055     -1.165407e-04 -1.222131e-04 -1.281670e-04 -1.344169e-04
## ASV0032      6.185089e-05  6.459819e-05  6.745785e-05  7.043354e-05
## ASV2977     -1.975341e-03 -2.067646e-03 -2.164183e-03 -2.265136e-03
## ASV0466      1.644122e-03  1.719196e-03  1.797545e-03  1.879295e-03
## ASV3866      1.067942e-03  1.118391e-03  1.171204e-03  1.226489e-03
## ASV0040      3.895978e-04  4.078821e-04  4.270118e-04  4.470246e-04
## ASV0496     -6.933581e-05 -7.331605e-05 -7.754910e-05 -8.205276e-05
## ASV0052      3.267852e-04  3.421322e-04  3.581897e-04  3.749895e-04
## ASV3828     -1.189002e-03 -1.243200e-03 -1.299755e-03 -1.358758e-03
## ASV1930      5.984157e-04  6.260697e-04  6.549604e-04  6.851392e-04
## ASV2126      1.009944e-03  1.056904e-03  1.105993e-03  1.157303e-03
## ASV0793      1.212794e-03  1.269995e-03  1.329867e-03  1.392533e-03
## ASV0299     -2.343605e-05 -2.454389e-05 -2.570434e-05 -2.692002e-05
## ASV0208      8.825554e-04  9.239617e-04  9.672811e-04  1.012599e-03
## ASV0511     -3.806117e-04 -3.979303e-04 -4.159974e-04 -4.348418e-04
## ASV1123     -1.147100e-03 -1.199398e-03 -1.253969e-03 -1.310901e-03
## ASV0099      3.035020e-05  3.185291e-05  3.343278e-05  3.509402e-05
## ASV0752     -6.146325e-04 -6.439022e-04 -6.745649e-04 -7.066866e-04
## ASV0883      8.453767e-04  8.855609e-04  9.276506e-04  9.717356e-04
## ASV0683      1.112174e-03  1.164813e-03  1.219926e-03  1.277630e-03
## ASV4117     -1.796857e-03 -1.881078e-03 -1.969185e-03 -2.061350e-03
## ASV2172      1.270687e-04  1.327067e-04  1.385741e-04  1.446783e-04
## ASV0330     -3.337146e-04 -3.494233e-04 -3.658629e-04 -3.830663e-04
## ASV0728      1.667061e-03  1.744985e-03  1.826481e-03  1.911705e-03
## ASV0499      4.319145e-04  4.523814e-04  4.738132e-04  4.962550e-04
## ASV0120     -7.384467e-04 -7.729921e-04 -8.091235e-04 -8.469109e-04
## ASV1446      6.106046e-04  6.377888e-04  6.660917e-04  6.955508e-04
## ASV17171    -1.431573e-03 -1.498342e-03 -1.568160e-03 -1.641162e-03
## ASV0533      1.013217e-04  1.062122e-04  1.113417e-04  1.167220e-04
## ASV2495     -3.266766e-04 -3.426322e-04 -3.593862e-04 -3.769805e-04
## ASV5582      6.983959e-04  7.298601e-04  7.626546e-04  7.968276e-04
## ASV1488      2.574652e-04  2.693426e-04  2.817494e-04  2.947071e-04
## ASV0682      3.135028e-04  3.283970e-04  3.439970e-04  3.603360e-04
## ASV0068     -5.577372e-04 -5.838739e-04 -6.112150e-04 -6.398140e-04
## ASV1987     -1.352447e-03 -1.416936e-03 -1.484503e-03 -1.555293e-03
## ASV0035     -8.833732e-05 -9.292043e-05 -9.775747e-05 -1.028639e-04
## ASV7192     -8.786240e-04 -9.193226e-04 -9.618527e-04 -1.006292e-03
## ASV0873      1.884542e-04  1.881706e-04  1.870273e-04  1.849089e-04
## ASV4749      1.951806e-05  1.897068e-05  1.825901e-05  1.736260e-05
## ASV2174      6.331926e-04  6.618586e-04  6.917503e-04  7.229131e-04
## ASV1476     -6.043654e-04 -6.330115e-04 -6.630099e-04 -6.944240e-04
## ASV0740     -1.716934e-03 -1.798330e-03 -1.883566e-03 -1.972822e-03
## ASV0170     -3.419503e-04 -3.579775e-04 -3.747435e-04 -3.922815e-04
## ASV2466     -1.559354e-03 -1.632409e-03 -1.708831e-03 -1.788770e-03
## ASV1709      5.877123e-04  6.147244e-04  6.429342e-04  6.723909e-04
## ASV6170     -2.415039e-03 -2.529022e-03 -2.648337e-03 -2.773226e-03
## ASV3673      1.178289e-03  1.234139e-03  1.292624e-03  1.353867e-03
## ASV1745     -2.978610e-04 -3.122063e-04 -3.272495e-04 -3.430253e-04
##                                                                    
## (Intercept)  9.970352e-03  1.043662e-02  1.092427e-02  1.143425e-02
## ASV1236      2.009509e-03  2.101836e-03  2.198246e-03  2.298906e-03
## ASV0421      2.033679e-04  2.137484e-04  2.246874e-04  2.362172e-04
## ASV0691     -1.616207e-03 -1.688369e-03 -1.763524e-03 -1.841772e-03
## ASV0899      1.735949e-03  1.815966e-03  1.899542e-03  1.986825e-03
## ASV1004      4.015278e-03  4.200127e-03  4.393183e-03  4.594781e-03
## ASV1041     -1.654716e-03 -1.730786e-03 -1.810219e-03 -1.893153e-03
## ASV1058      2.508636e-03  2.624014e-03  2.744503e-03  2.870314e-03
## ASV12542     9.831337e-04  1.027930e-03  1.074671e-03  1.123434e-03
## ASV1294      2.332919e-03  2.440286e-03  2.552417e-03  2.669507e-03
## ASV13113     7.472172e-04  7.828964e-04  8.202833e-04  8.594599e-04
## ASV1318      2.327149e-03  2.434221e-03  2.546042e-03  2.662804e-03
## ASV2269     -4.035304e-03 -4.220756e-03 -4.414410e-03 -4.616599e-03
## ASV2542      1.914404e-03  2.004462e-03  2.098703e-03  2.197319e-03
## ASV2660     -1.610220e-03 -1.684039e-03 -1.761106e-03 -1.841551e-03
## ASV2737      5.684405e-04  5.940488e-04  6.207415e-04  6.485580e-04
## ASV2840      2.170002e-03  2.268564e-03  2.371374e-03  2.478591e-03
## ASV3053      1.105043e-02  1.155449e-02  1.208049e-02  1.262928e-02
## ASV3077      7.035662e-04  7.357051e-04  7.692475e-04  8.042488e-04
## ASV3134      1.202116e-03  1.259131e-03  1.318840e-03  1.381368e-03
## ASV3140      1.659307e-03  1.736796e-03  1.817830e-03  1.902565e-03
## ASV3579      5.647460e-04  5.920711e-04  6.207370e-04  6.508111e-04
## ASV6119     -1.104347e-03 -1.155095e-03 -1.208086e-03 -1.263413e-03
## ASV7557     -2.244088e-03 -2.347200e-03 -2.454870e-03 -2.567283e-03
## ASV8422      5.635379e-04  5.892565e-04  6.160959e-04  6.441003e-04
## ASV1086     -9.159723e-05 -9.562618e-05 -9.981649e-05 -1.041731e-04
## ASV1310      1.074297e-03  1.123703e-03  1.175297e-03  1.229168e-03
## ASV15750    -1.501735e-04 -1.569197e-04 -1.639492e-04 -1.712721e-04
## ASV16905    -4.614605e-04 -4.826638e-04 -5.048044e-04 -5.279203e-04
## ASV2033      1.912072e-03  2.002458e-03  2.097084e-03  2.196143e-03
## ASV2089      9.725912e-04  1.017300e-03  1.063987e-03  1.112733e-03
## ASV2127      3.157640e-03  3.302835e-03  3.454461e-03  3.612779e-03
## ASV2725      2.543487e-03  2.659719e-03  2.781030e-03  2.907620e-03
## ASV2804     -9.552467e-04 -9.991362e-04 -1.044966e-03 -1.092814e-03
## ASV3075      2.067553e-03  2.163659e-03  2.264123e-03  2.369133e-03
## ASV3327      2.827133e-03  2.959994e-03  3.099013e-03  3.244467e-03
## ASV3342      2.437306e-03  2.551510e-03  2.670977e-03  2.795942e-03
## ASV3532     -2.703318e-03 -2.829364e-03 -2.961161e-03 -3.098959e-03
## ASV3600      1.253919e-03  1.312500e-03  1.373765e-03  1.437831e-03
## ASV4013      2.361061e-03  2.470413e-03  2.584682e-03  2.704076e-03
## ASV4136      2.551333e-03  2.668001e-03  2.789777e-03  2.916862e-03
## ASV4195      9.750573e-03  1.019852e-02  1.066626e-02  1.115460e-02
## ASV4407     -3.767120e-03 -3.940165e-03 -4.120857e-03 -4.309504e-03
## ASV4717      6.721066e-04  7.022527e-04  7.336623e-04  7.663800e-04
## ASV6794      1.579060e-03  1.650786e-03  1.725606e-03  1.803639e-03
## ASV8324     -1.932991e-03 -2.021786e-03 -2.114504e-03 -2.211303e-03
## ASV8981     -5.829098e-05 -6.051485e-05 -6.279313e-05 -6.512372e-05
## ASV9859      6.301983e-04  6.609011e-04  6.931308e-04  7.269661e-04
## ASV0936      1.836168e-03  1.922284e-03  2.012374e-03  2.106615e-03
## ASV12683     1.491981e-06  1.397166e-06  1.282867e-06  1.146879e-06
## ASV1293      1.255099e-03  1.312698e-03  1.372837e-03  1.435618e-03
## ASV13055    -3.719349e-05 -3.856971e-05 -3.997462e-05 -4.140626e-05
## ASV17063    -1.002787e-03 -1.048834e-03 -1.096915e-03 -1.147110e-03
## ASV2228      8.177496e-04  8.552967e-04  8.945012e-04  9.354300e-04
## ASV2769      1.170196e-04  1.229161e-04  1.291227e-04  1.356568e-04
## ASV2803      8.974243e-04  9.380678e-04  9.804522e-04  1.024643e-03
## ASV2896      6.904925e-04  7.229571e-04  7.569292e-04  7.924773e-04
## ASV3062      8.161604e-04  8.553408e-04  8.964151e-04  9.394760e-04
## ASV3107      1.291368e-03  1.351894e-03  1.415211e-03  1.481444e-03
## ASV3265      1.797474e-03  1.879890e-03  1.965932e-03  2.055747e-03
## ASV3666      1.852848e-05  1.933240e-05  2.016690e-05  2.103266e-05
## ASV4497      6.142377e-04  6.425478e-04  6.721180e-04  7.030001e-04
## ASV6914     -8.506203e-05 -8.928855e-05 -9.373269e-05 -9.840630e-05
## ASV0576     -2.179682e-03 -2.278051e-03 -2.380601e-03 -2.487485e-03
## ASV0673      2.357779e-03  2.466814e-03  2.580737e-03  2.699752e-03
## ASV0772      1.090929e-03  1.141530e-03  1.194415e-03  1.249680e-03
## ASV0862      7.657750e-05  8.144118e-05  8.664875e-05  9.222661e-05
## ASV0898      8.286770e-04  8.679827e-04  9.091440e-04  9.522473e-04
## ASV0910      9.655137e-04  1.010882e-03  1.058353e-03  1.108022e-03
## ASV0964     -8.195031e-04 -8.567023e-04 -8.955024e-04 -9.359641e-04
## ASV10059     6.771867e-04  7.094635e-04  7.432793e-04  7.787076e-04
## ASV10263    -1.526982e-03 -1.597139e-03 -1.670396e-03 -1.746880e-03
## ASV1088      1.729137e-03  1.810018e-03  1.894614e-03  1.983092e-03
## ASV1101      2.185712e-03  2.286013e-03  2.390735e-03  2.500057e-03
## ASV1183      5.687526e-04  5.952698e-04  6.229964e-04  6.519852e-04
## ASV11956     5.698199e-04  5.954892e-04  6.222450e-04  6.501269e-04
## ASV12774     4.091839e-05  4.240776e-05  4.392522e-05  4.546824e-05
## ASV1321      2.484132e-03  2.601263e-03  2.723861e-03  2.852176e-03
## ASV13793    -1.052843e-03 -1.101214e-03 -1.151722e-03 -1.204455e-03
## ASV14482     7.044392e-05  7.351856e-05  7.671439e-05  8.003504e-05
## ASV15483     4.238200e-04  4.437177e-04  4.645358e-04  4.863155e-04
## ASV2062      2.004617e-03  2.097346e-03  2.194235e-03  2.295459e-03
## ASV2132      1.614889e-03  1.690603e-03  1.769809e-03  1.852663e-03
## ASV2413      1.558941e-03  1.630637e-03  1.705510e-03  1.783690e-03
## ASV2490      4.844794e-03  5.065517e-03  5.295821e-03  5.536079e-03
## ASV2594      5.915585e-04  6.191386e-04  6.479780e-04  6.781315e-04
## ASV2822     -2.778223e-03 -2.905888e-03 -3.039197e-03 -3.178381e-03
## ASV2863      2.969179e-03  3.104981e-03  3.246730e-03  3.394662e-03
## ASV2910      1.082802e-03  1.132504e-03  1.184399e-03  1.238575e-03
## ASV2980      1.197191e-03  1.252649e-03  1.310603e-03  1.371157e-03
## ASV3307      2.210579e-03  2.312140e-03  2.418190e-03  2.528910e-03
## ASV3474      1.416089e-03  1.483159e-03  1.553386e-03  1.626919e-03
## ASV3502      1.513471e-03  1.583935e-03  1.657603e-03  1.734614e-03
## ASV4236      2.283134e-03  2.386929e-03  2.495206e-03  2.608137e-03
## ASV4842     -2.349619e-04 -2.461329e-04 -2.578318e-04 -2.700828e-04
## ASV4894     -1.052980e-03 -1.101364e-03 -1.151887e-03 -1.204636e-03
## ASV5290      8.207009e-04  8.591251e-04  8.993165e-04  9.413535e-04
## ASV5501      5.049147e-04  5.283961e-04  5.529439e-04  5.786043e-04
## ASV5795      5.507600e-04  5.765782e-04  6.035871e-04  6.318396e-04
## ASV5987     -2.941072e-03 -3.076223e-03 -3.217352e-03 -3.364700e-03
## ASV6267     -3.313898e-03 -3.466167e-03 -3.625169e-03 -3.791177e-03
## ASV6862      1.341319e-03  1.402441e-03  1.466219e-03  1.532755e-03
## ASV7145      5.969477e-04  6.239222e-04  6.520483e-04  6.813690e-04
## ASV7673     -1.052942e-03 -1.101322e-03 -1.151842e-03 -1.204587e-03
## ASV7789      4.930909e-04  5.170241e-04  5.421388e-04  5.684951e-04
## ASV7809      2.437454e-05  2.599252e-05  2.772963e-05  2.959529e-05
## ASV8002     -1.329819e-03 -1.390920e-03 -1.454722e-03 -1.521335e-03
## ASV8205      5.473420e-04  5.729135e-04  5.996563e-04  6.276221e-04
## ASV9155     -3.412032e-04 -3.567436e-04 -3.729579e-04 -3.898720e-04
## ASV9221      1.169760e-04  1.232148e-04  1.298127e-04  1.367925e-04
## ASV9311     -2.133256e-03 -2.231267e-03 -2.333610e-03 -2.440461e-03
## ASV9557     -1.457876e-03 -1.524851e-03 -1.594785e-03 -1.667799e-03
## ASV9936     -2.939917e-03 -3.074963e-03 -3.215975e-03 -3.363196e-03
## ASV1445      1.753936e-03  1.835930e-03  1.921684e-03  2.011364e-03
## ASV4232      6.503957e-04  6.813738e-04  7.138281e-04  7.478290e-04
## ASV6479      2.125647e-04  2.235650e-04  2.351701e-04  2.474161e-04
## ASV0142     -1.271432e-03 -1.329657e-03 -1.390437e-03 -1.453876e-03
## ASV0378      5.536727e-04  5.800704e-04  6.077274e-04  6.367040e-04
## ASV1122      1.692369e-03  1.771716e-03  1.854723e-03  1.941554e-03
## ASV0123     -1.123716e-03 -1.175136e-03 -1.228808e-03 -1.284824e-03
## ASV2064      5.855912e-04  6.119349e-04  6.393890e-04  6.679932e-04
## ASV4459     -8.529222e-05 -8.898191e-05 -9.281334e-05 -9.679027e-05
## ASV0448      4.424063e-04  4.635157e-04  4.856337e-04  5.088083e-04
## ASV0397      1.004961e-03  1.051638e-03  1.100428e-03  1.151419e-03
## ASV0485      1.175029e-03  1.229293e-03  1.285983e-03  1.345200e-03
## ASV1566      1.722610e-03  1.802535e-03  1.886069e-03  1.973364e-03
## ASV1365      1.462973e-03  1.531211e-03  1.602562e-03  1.677163e-03
## ASV1065      2.081736e-03  2.178708e-03  2.280095e-03  2.386088e-03
## ASV0722     -1.068198e-04 -1.118720e-04 -1.171617e-04 -1.227000e-04
## ASV12660    -1.220530e-03 -1.276249e-03 -1.334400e-03 -1.395077e-03
## ASV0223      3.240415e-04  3.390273e-04  3.546854e-04  3.710440e-04
## ASV0229      4.869527e-04  5.097981e-04  5.336994e-04  5.587037e-04
## ASV0877      2.146047e-04  2.242415e-04  2.342814e-04  2.447386e-04
## ASV0983      1.169145e-03  1.223023e-03  1.279299e-03  1.338071e-03
## ASV0626      1.051769e-04  1.109269e-04  1.170185e-04  1.234739e-04
## ASV4146      5.748595e-05  6.015177e-05  6.293639e-05  6.584453e-05
## ASV4175     -1.416213e-03 -1.482536e-03 -1.551911e-03 -1.624475e-03
## ASV2082     -5.995791e-04 -6.292742e-04 -6.604904e-04 -6.933097e-04
## ASV2272      6.762315e-04  7.078109e-04  7.408361e-04  7.753706e-04
## ASV2245     -1.008701e-03 -1.056061e-03 -1.105611e-03 -1.157450e-03
## ASV0590     -5.540489e-04 -5.820225e-04 -6.114754e-04 -6.424913e-04
## ASV0217      2.486548e-05  2.723786e-05  2.983289e-05  3.267094e-05
## ASV0416      8.065962e-04  8.427035e-04  8.803161e-04  9.194863e-04
## ASV1056      9.685081e-04  1.014280e-03  1.062198e-03  1.112361e-03
## ASV7777     -1.382396e-03 -1.446951e-03 -1.514461e-03 -1.585055e-03
## ASV0455      2.489888e-04  2.605804e-04  2.726989e-04  2.853672e-04
## ASV0604      6.336580e-04  6.637781e-04  6.953260e-04  7.283692e-04
## ASV6100     -9.467760e-04 -9.912354e-04 -1.037753e-03 -1.086422e-03
## ASV11359    -2.046960e-03 -2.142598e-03 -2.242617e-03 -2.347209e-03
## ASV6604      2.793569e-04  2.926045e-04  3.064773e-04  3.210045e-04
## ASV5004     -7.309336e-04 -7.649552e-04 -8.005235e-04 -8.377053e-04
## ASV1483     -3.158214e-04 -3.304819e-04 -3.458050e-04 -3.618188e-04
## ASV9773     -9.198158e-04 -9.628822e-04 -1.007930e-03 -1.055048e-03
## ASV4059     -1.909079e-05 -1.906833e-05 -1.895850e-05 -1.874938e-05
## ASV1193      1.120377e-03  1.172449e-03  1.226881e-03  1.283774e-03
## ASV4610     -2.060688e-04 -2.143359e-04 -2.228561e-04 -2.316290e-04
## ASV0742     -1.305124e-04 -1.355216e-04 -1.406582e-04 -1.459183e-04
## ASV1502     -3.522056e-05 -3.752129e-05 -3.998926e-05 -4.263759e-05
## ASV0195      3.647209e-05  3.775354e-05  3.905441e-05  4.037195e-05
## ASV1213      8.129892e-04  8.497430e-04  8.880650e-04  9.280132e-04
## ASV1648     -8.511821e-04 -8.911124e-04 -9.328879e-04 -9.765915e-04
## ASV6984     -7.960213e-04 -8.333777e-04 -8.724618e-04 -9.133514e-04
## ASV0396     -5.597728e-05 -5.811665e-05 -6.030979e-05 -6.255504e-05
## ASV4297      1.169293e-03  1.222585e-03  1.278191e-03  1.336202e-03
## ASV2622      1.796666e-03  1.879278e-03  1.965548e-03  2.055626e-03
## ASV3512      6.601306e-04  6.921756e-04  7.258034e-04  7.610945e-04
## ASV2411      1.187575e-03  1.243765e-03  1.302596e-03  1.364190e-03
## ASV2291     -4.737811e-04 -4.979519e-04 -5.234220e-04 -5.502665e-04
## ASV0807      1.649628e-03  1.726322e-03  1.806494e-03  1.890292e-03
## ASV1292      4.147096e-04  4.332647e-04  4.525929e-04  4.727211e-04
## ASV1035      1.537609e-03  1.607976e-03  1.681430e-03  1.758094e-03
## ASV0070      3.262348e-06  3.843293e-06  4.491659e-06  5.214277e-06
## ASV0255      1.487229e-04  1.554044e-04  1.623663e-04  1.696186e-04
## ASV0057     -4.282568e-04 -4.476380e-04 -4.678476e-04 -4.889166e-04
## ASV0077     -9.455946e-05 -9.867929e-05 -1.029596e-04 -1.074048e-04
## ASV0625      8.884150e-04  9.289526e-04  9.712557e-04  1.015393e-03
## ASV2464      6.060635e-03  6.336373e-03  6.624055e-03  6.924143e-03
## ASV1315      1.543438e-03  1.616641e-03  1.693300e-03  1.773577e-03
## ASV2673      1.322956e-03  1.385745e-03  1.451502e-03  1.520367e-03
## ASV2161      5.604882e-04  5.870390e-04  6.148410e-04  6.439523e-04
## ASV0337     -3.243773e-04 -3.395886e-04 -3.555018e-04 -3.721483e-04
## ASV7680     -2.114034e-03 -2.213294e-03 -2.317147e-03 -2.425800e-03
## ASV0611      1.179908e-03  1.235340e-03  1.293341e-03  1.354026e-03
## ASV3118     -1.209360e-03 -1.266904e-03 -1.327183e-03 -1.390326e-03
## ASV1284      5.048604e-04  5.254955e-04  5.467965e-04  5.687665e-04
## ASV0889      9.097850e-04  9.517239e-04  9.955311e-04  1.041284e-03
## ASV4649     -4.505336e-04 -4.715454e-04 -4.935162e-04 -5.164879e-04
## ASV1108     -8.989422e-04 -9.419815e-04 -9.870914e-04 -1.034372e-03
## ASV0738      4.826217e-04  5.063882e-04  5.313592e-04  5.575985e-04
## ASV0473     -9.203868e-05 -9.687379e-05 -1.019798e-04 -1.073730e-04
## ASV0598     -2.415796e-04 -2.537136e-04 -2.664844e-04 -2.799277e-04
## ASV0429      6.797665e-04  7.109069e-04  7.434145e-04  7.773437e-04
## ASV1549      1.219796e-03  1.277729e-03  1.338405e-03  1.401953e-03
## ASV1203      9.872945e-04  1.032914e-03  1.080575e-03  1.130363e-03
## ASV4532      4.684440e-05  4.879947e-05  5.082274e-05  5.291533e-05
## ASV0274      1.638356e-04  1.717907e-04  1.801383e-04  1.888980e-04
## ASV0163     -7.733770e-04 -8.085923e-04 -8.453346e-04 -8.836632e-04
## ASV1298      8.883191e-05  9.267171e-05  9.665923e-05  1.007985e-04
## ASV9424     -1.635302e-03 -1.712242e-03 -1.792759e-03 -1.877014e-03
## ASV0412      1.718052e-03  1.797181e-03  1.879828e-03  1.966138e-03
## ASV0284      3.732169e-04  3.897458e-04  4.069464e-04  4.248403e-04
## ASV0620     -3.298574e-04 -3.461185e-04 -3.632048e-04 -3.811601e-04
## ASV0153     -1.630937e-03 -1.708396e-03 -1.789523e-03 -1.874488e-03
## ASV0498      5.813176e-04  6.086472e-04  6.372439e-04  6.671648e-04
## ASV0097      3.205154e-04  3.357297e-04  3.516638e-04  3.683514e-04
## ASV0104     -2.316743e-03 -2.424226e-03 -2.536559e-03 -2.653950e-03
## ASV1282      8.103222e-04  8.473763e-04  8.860507e-04  9.264089e-04
## ASV3883     -6.107417e-04 -6.402776e-04 -6.712605e-04 -7.037629e-04
## ASV0801      3.102991e-04  3.248734e-04  3.401223e-04  3.560759e-04
## ASV1611     -1.459670e-03 -1.528664e-03 -1.600893e-03 -1.676508e-03
## ASV0227     -2.483588e-04 -2.608508e-04 -2.739986e-04 -2.878387e-04
## ASV0833      5.004315e-04  5.238894e-04  5.484287e-04  5.740974e-04
## ASV0718      2.243880e-03  2.348788e-03  2.458509e-03  2.573255e-03
## ASV1139      3.130370e-04  3.265213e-04  3.405149e-04  3.550301e-04
## ASV0766     -3.031378e-04 -3.178291e-04 -3.332427e-04 -3.494148e-04
## ASV2091      1.864693e-03  1.949832e-03  2.038683e-03  2.131392e-03
## ASV1238     -1.657333e-03 -1.735353e-03 -1.817006e-03 -1.902455e-03
## ASV9193     -1.401990e-04 -1.477213e-04 -1.556808e-04 -1.641057e-04
## ASV0290      2.525210e-04  2.635998e-04  2.751190e-04  2.870918e-04
## ASV0231      6.763011e-04  7.074533e-04  7.399905e-04  7.739695e-04
## ASV0185      3.711150e-04  3.893487e-04  4.085028e-04  4.286257e-04
## ASV2330      7.866789e-04  8.223519e-04  8.595568e-04  8.983514e-04
## ASV3119     -3.370956e-04 -3.536062e-04 -3.709453e-04 -3.891561e-04
## ASV2368     -8.431722e-04 -8.832354e-04 -9.251986e-04 -9.691514e-04
## ASV0122     -4.186498e-04 -4.380159e-04 -4.582507e-04 -4.793909e-04
## ASV1044      1.051502e-03  1.101212e-03  1.153254e-03  1.207736e-03
## ASV0160     -4.575749e-04 -4.783408e-04 -5.000004e-04 -5.225873e-04
## ASV0326      1.171784e-04  1.226809e-04  1.284379e-04  1.344606e-04
## ASV1388      2.167945e-03  2.268431e-03  2.373444e-03  2.483173e-03
## ASV0792      1.624075e-03  1.698589e-03  1.776388e-03  1.857603e-03
## ASV0036     -4.890171e-04 -5.122559e-04 -5.365959e-04 -5.620888e-04
## ASV2125      1.545677e-03  1.617520e-03  1.692618e-03  1.771110e-03
## ASV1075     -2.333473e-05 -2.441232e-05 -2.553844e-05 -2.671520e-05
## ASV0390      8.080762e-04  8.464393e-04  8.866182e-04  9.286981e-04
## ASV3790     -1.160468e-03 -1.214923e-03 -1.271895e-03 -1.331497e-03
## ASV1535     -3.224985e-04 -3.382305e-04 -3.547463e-04 -3.720862e-04
## ASV0263      1.429292e-03  1.495969e-03  1.565691e-03  1.638591e-03
## ASV0675      2.127444e-03  2.227681e-03  2.332590e-03  2.442384e-03
## ASV3348      1.685503e-04  1.766847e-04  1.852163e-04  1.941645e-04
## ASV0058     -6.420426e-04 -6.717606e-04 -7.028133e-04 -7.352567e-04
## ASV4142      9.089702e-04  9.506500e-04  9.941630e-04  1.039582e-03
## ASV0059     -5.186855e-04 -5.426218e-04 -5.676261e-04 -5.937428e-04
## ASV0013     -9.131971e-04 -9.557651e-04 -1.000274e-03 -1.046807e-03
## ASV0033     -4.257637e-04 -4.459622e-04 -4.671146e-04 -4.892656e-04
## ASV4354     -5.378111e-04 -5.628749e-04 -5.890819e-04 -6.164822e-04
## ASV0022     -3.597232e-04 -3.767789e-04 -3.946394e-04 -4.133421e-04
## ASV0134     -3.371541e-04 -3.533849e-04 -3.704045e-04 -3.882516e-04
## ASV0415      5.073455e-05  5.335522e-05  5.611893e-05  5.903403e-05
## ASV10103    -2.009724e-03 -2.104437e-03 -2.203566e-03 -2.307313e-03
## ASV1613      1.538813e-03  1.609465e-03  1.683236e-03  1.760250e-03
## ASV0135     -2.006869e-04 -2.097650e-04 -2.192307e-04 -2.290982e-04
## ASV0469     -1.975442e-03 -2.066630e-03 -2.161891e-03 -2.261395e-03
## ASV0471      1.192377e-03  1.247893e-03  1.305934e-03  1.366608e-03
## ASV0451     -1.780486e-04 -1.871436e-04 -1.967285e-04 -2.068317e-04
## ASV0747      6.746374e-04  7.062344e-04  7.392856e-04  7.738556e-04
## ASV1314     -6.669644e-04 -6.986927e-04 -7.319287e-04 -7.667440e-04
## ASV0425     -2.466440e-03 -2.579326e-03 -2.697162e-03 -2.820144e-03
## ASV0559     -6.016468e-04 -6.295602e-04 -6.587352e-04 -6.892258e-04
## ASV0148     -1.472121e-04 -1.535374e-04 -1.600998e-04 -1.669048e-04
## ASV0129      1.182299e-04  1.247529e-04  1.316699e-04  1.390073e-04
## ASV1072      1.682591e-04  1.757534e-04  1.835559e-04  1.916769e-04
## ASV2390      1.273692e-03  1.331544e-03  1.391888e-03  1.454819e-03
## ASV0548      8.215700e-04  8.597710e-04  8.997043e-04  9.414442e-04
## ASV0168     -4.251189e-04 -4.447286e-04 -4.652127e-04 -4.866074e-04
## ASV0066     -4.771473e-04 -4.992433e-04 -5.223324e-04 -5.464566e-04
## ASV0468     -2.505276e-04 -2.622276e-04 -2.744633e-04 -2.872581e-04
## ASV0172     -1.491626e-04 -1.557852e-04 -1.626782e-04 -1.698503e-04
## ASV0236     -5.484101e-05 -5.608251e-05 -5.725572e-05 -5.834585e-05
## ASV0250      6.436048e-04  6.747552e-04  7.074356e-04  7.417230e-04
## ASV0338      3.109289e-04  3.257213e-04  3.412153e-04  3.574438e-04
## ASV0450     -5.302746e-05 -5.579385e-05 -5.871419e-05 -6.179781e-05
## ASV0377      5.969566e-04  6.245569e-04  6.533939e-04  6.835196e-04
## ASV1022     -2.625446e-05 -2.743298e-05 -2.866044e-05 -2.993844e-05
## ASV6174     -1.010489e-05 -1.070275e-05 -1.134058e-05 -1.202143e-05
## ASV0786     -7.044337e-05 -7.429841e-05 -7.838247e-05 -8.271040e-05
## ASV0053     -6.391678e-04 -6.690288e-04 -7.002572e-04 -7.329132e-04
## ASV0697     -3.958178e-04 -4.139741e-04 -4.329307e-04 -4.527198e-04
## ASV0785      8.266288e-04  8.648620e-04  9.048096e-04  9.465435e-04
## ASV1967     -8.246902e-04 -8.626637e-04 -9.023254e-04 -9.437450e-04
## ASV0385      2.677021e-04  2.804939e-04  2.938981e-04  3.079440e-04
## ASV0295      3.988188e-05  4.214410e-05  4.454793e-05  4.710319e-05
## ASV0072     -6.460731e-04 -6.757850e-04 -7.068126e-04 -7.392094e-04
## ASV0157     -9.424959e-05 -9.804181e-05 -1.019494e-04 -1.059719e-04
## ASV0501      1.378028e-03  1.442503e-03  1.509939e-03  1.580469e-03
## ASV10729    -1.726745e-03 -1.807775e-03 -1.892550e-03 -1.981238e-03
## ASV1470      9.121159e-04  9.534197e-04  9.964914e-04  1.041397e-03
## ASV0050     -1.510075e-03 -1.580012e-03 -1.653094e-03 -1.729453e-03
## ASV0411     -3.334215e-04 -3.492064e-04 -3.657339e-04 -3.830384e-04
## ASV0549      5.386936e-04  5.640666e-04  5.906211e-04  6.184109e-04
## ASV0184      1.831665e-04  1.916436e-04  2.005018e-04  2.097573e-04
## ASV0705      3.648072e-04  3.815836e-04  3.991027e-04  4.173948e-04
## ASV1715      7.601744e-04  7.956613e-04  8.327708e-04  8.715738e-04
## ASV0603      1.169709e-04  1.224960e-04  1.282805e-04  1.343364e-04
## ASV0826      1.290643e-03  1.350554e-03  1.413171e-03  1.478612e-03
## ASV0034     -4.168292e-04 -4.360203e-04 -4.560634e-04 -4.769935e-04
## ASV0838      3.140565e-04  3.273070e-04  3.410281e-04  3.552273e-04
## ASV0614     -3.537051e-04 -3.701066e-04 -3.872477e-04 -4.051602e-04
## ASV0014     -9.349202e-04 -9.783937e-04 -1.023839e-03 -1.071340e-03
## ASV0585      1.269534e-04  1.317738e-04  1.367101e-04  1.417574e-04
## ASV0016     -9.766743e-04 -1.022089e-03 -1.069562e-03 -1.119184e-03
## ASV5394     -7.275757e-04 -7.616224e-04 -7.972336e-04 -8.344784e-04
## ASV0666      1.620177e-03  1.694455e-03  1.772001e-03  1.852947e-03
## ASV2085      4.070736e-04  4.241889e-04  4.419090e-04  4.602435e-04
## ASV0003     -6.662883e-04 -6.972558e-04 -7.296262e-04 -7.634598e-04
## ASV0346      3.268181e-04  3.423860e-04  3.586949e-04  3.757797e-04
## ASV0267     -1.056510e-05 -1.070184e-05 -1.081076e-05 -1.088739e-05
## ASV0353      5.236540e-04  5.483974e-04  5.743006e-04  6.014169e-04
## ASV2419      1.439994e-03  1.506657e-03  1.576315e-03  1.649095e-03
## ASV0447      7.663908e-04  8.026713e-04  8.406582e-04  8.804306e-04
## ASV0654      1.155361e-03  1.209135e-03  1.265352e-03  1.324117e-03
## ASV0151      1.448108e-04  1.519732e-04  1.595017e-04  1.674159e-04
## ASV0065     -4.493343e-04 -4.701457e-04 -4.918932e-04 -5.146162e-04
## ASV0527      1.102010e-03  1.153179e-03  1.206661e-03  1.262555e-03
## ASV4055     -1.672764e-04 -1.753530e-04 -1.838252e-04 -1.927127e-04
## ASV0166     -5.608435e-04 -5.865564e-04 -6.134008e-04 -6.414220e-04
## ASV0417     -2.341507e-04 -2.446761e-04 -2.556446e-04 -2.670718e-04
## ASV0078     -3.310609e-04 -3.462988e-04 -3.622128e-04 -3.788303e-04
## ASV0322     -6.710281e-05 -6.991170e-05 -7.281698e-05 -7.581962e-05
## ASV0156     -7.721338e-04 -8.083577e-04 -8.462554e-04 -8.859019e-04
## ASV0648     -1.672185e-03 -1.750847e-03 -1.833162e-03 -1.919297e-03
## ASV0407     -1.237274e-04 -1.296218e-04 -1.357971e-04 -1.422667e-04
## ASV2030     -2.850284e-04 -2.981166e-04 -3.117853e-04 -3.260587e-04
## ASV0300      1.971577e-04  2.065447e-04  2.163782e-04  2.266795e-04
## ASV1150      4.207200e-05  4.418010e-05  4.639808e-05  4.873202e-05
## ASV0958      6.085901e-04  6.375865e-04  6.679649e-04  6.997912e-04
## ASV0216     -6.959622e-04 -7.280768e-04 -7.616256e-04 -7.966685e-04
## ASV0446      1.030199e-03  1.078680e-03  1.129414e-03  1.182503e-03
## ASV0367     -6.790906e-04 -7.108566e-04 -7.440815e-04 -7.788295e-04
## ASV0200     -4.042521e-04 -4.231497e-04 -4.429139e-04 -4.635828e-04
## ASV0334     -2.342558e-04 -2.445166e-04 -2.551835e-04 -2.662685e-04
## ASV1311      2.779600e-04  2.903866e-04  3.033294e-04  3.168060e-04
## ASV0458      4.136307e-04  4.319884e-04  4.510967e-04  4.709802e-04
## ASV1371      6.095937e-05  6.393759e-05  6.706421e-05  7.034684e-05
## ASV0418      9.212050e-04  9.633252e-04  1.007288e-03  1.053168e-03
## ASV0004      1.339187e-04  1.400257e-04  1.463982e-04  1.530467e-04
## ASV1943      2.656043e-03  2.772937e-03  2.894525e-03  3.020955e-03
## ASV1495     -1.587852e-04 -1.671982e-04 -1.760911e-04 -1.854937e-04
## ASV0901     -7.559262e-04 -7.915953e-04 -8.289322e-04 -8.680134e-04
## ASV0628      4.198503e-04  4.388305e-04  4.586197e-04  4.792477e-04
## ASV0400      2.512560e-04  2.627998e-04  2.748536e-04  2.874380e-04
## ASV0116     -2.225481e-04 -2.330382e-04 -2.440176e-04 -2.555087e-04
## ASV0788      1.964574e-03  2.057296e-03  2.154354e-03  2.255948e-03
## ASV0117      1.425186e-04  1.493498e-04  1.565104e-04  1.640162e-04
## ASV3137     -4.725731e-05 -4.942874e-05 -5.169619e-05 -5.406357e-05
## ASV0001      1.441780e-04  1.507357e-04  1.575769e-04  1.647126e-04
## ASV1651      4.089007e-04  4.275836e-04  4.470827e-04  4.674301e-04
## ASV1692      1.637614e-03  1.714841e-03  1.795672e-03  1.880275e-03
## ASV0660      6.132537e-04  6.408420e-04  6.695928e-04  6.995475e-04
## ASV0508      3.119795e-05  3.258063e-05  3.401969e-05  3.551696e-05
## ASV1660     -3.200840e-04 -3.356483e-04 -3.519825e-04 -3.691257e-04
## ASV0233      5.106422e-04  5.344970e-04  5.594444e-04  5.855323e-04
## ASV1343     -9.341409e-04 -9.781214e-04 -1.024149e-03 -1.072316e-03
## ASV0209      4.816937e-04  5.036253e-04  5.265073e-04  5.503765e-04
## ASV0193     -5.603483e-04 -5.859538e-04 -6.126777e-04 -6.405642e-04
## ASV0357      1.986744e-04  2.084849e-04  2.187955e-04  2.296331e-04
## ASV0198      4.207535e-04  4.401933e-04  4.605031e-04  4.817190e-04
## ASV0007      1.282158e-04  1.340055e-04  1.400415e-04  1.463329e-04
## ASV1772     -1.925651e-04 -2.011926e-04 -2.101791e-04 -2.195366e-04
## ASV0009      1.067706e-04  1.115545e-04  1.165383e-04  1.217289e-04
## ASV0006     -1.094388e-04 -1.146692e-04 -1.201504e-04 -1.258943e-04
## ASV0011     -3.860994e-04 -4.042397e-04 -4.232205e-04 -4.430796e-04
## ASV0015      8.071592e-05  8.433209e-05  8.809925e-05  9.202266e-05
## ASV0017      9.088722e-05  9.496055e-05  9.920415e-05  1.036240e-04
## ASV0235     -3.556303e-04 -3.723931e-04 -3.899375e-04 -4.082990e-04
## ASV0382      2.782421e-04  2.913707e-04  3.051120e-04  3.194938e-04
## ASV2357      1.164030e-03  1.218675e-03  1.275848e-03  1.335662e-03
## ASV0567     -2.246042e-04 -2.351839e-04 -2.462570e-04 -2.578460e-04
## ASV0165      1.941901e-04  2.033088e-04  2.128494e-04  2.228309e-04
## ASV0005      2.846043e-04  2.978347e-04  3.116647e-04  3.261200e-04
## ASV0384     -3.756099e-05 -3.900364e-05 -4.048258e-05 -4.199657e-05
## ASV0002      5.407343e-05  5.654788e-05  5.913088e-05  6.182675e-05
## ASV3017      1.532160e-03  1.602233e-03  1.675371e-03  1.751698e-03
## ASV0091     -3.858419e-05 -4.035819e-05 -4.221093e-05 -4.414569e-05
## ASV0186     -5.720971e-04 -5.987650e-04 -6.266484e-04 -6.557999e-04
## ASV0370      3.060866e-04  3.202321e-04  3.350105e-04  3.504483e-04
## ASV0018      3.640575e-04  3.810063e-04  3.987256e-04  4.172486e-04
## ASV1377      3.701229e-03  3.871152e-03  4.048574e-03  4.233800e-03
## ASV0019      3.817614e-04  3.995420e-04  4.181317e-04  4.375654e-04
## ASV0023     -2.355668e-04 -2.466813e-04 -2.583152e-04 -2.704922e-04
## ASV2194      3.766814e-04  3.945416e-04  4.132451e-04  4.328314e-04
## ASV1155      1.551870e-03  1.622909e-03  1.697069e-03  1.774477e-03
## ASV0510     -4.244388e-04 -4.435018e-04 -4.633647e-04 -4.840556e-04
## ASV2371     -9.339774e-04 -9.767665e-04 -1.021438e-03 -1.068067e-03
## ASV0024     -2.937783e-04 -3.076182e-04 -3.221028e-04 -3.372615e-04
## ASV2452      9.508634e-04  9.938813e-04  1.038736e-03  1.085496e-03
## ASV2332     -2.670709e-03 -2.793590e-03 -2.921926e-03 -3.055943e-03
## ASV2591      6.534026e-04  6.856328e-04  7.194944e-04  7.550729e-04
## ASV0521      5.973198e-04  6.254366e-04  6.548613e-04  6.856531e-04
## ASV5542      5.709841e-04  5.979201e-04  6.261124e-04  6.556179e-04
## ASV0336     -6.426380e-05 -6.765577e-05 -7.123961e-05 -7.502712e-05
## ASV10102     1.056692e-03  1.106432e-03  1.158485e-03  1.212955e-03
## ASV16823    -1.694206e-03 -1.770959e-03 -1.851007e-03 -1.934476e-03
## ASV3104      8.765385e-03  9.162449e-03  9.576556e-03  1.000835e-02
## ASV0781      1.192813e-03  1.248287e-03  1.306277e-03  1.366892e-03
## ASV10899     6.602755e-04  6.928351e-04  7.270465e-04  7.629971e-04
## ASV11222    -2.981602e-03 -3.116659e-03 -3.257512e-03 -3.404381e-03
## ASV11327    -2.676707e-03 -2.797942e-03 -2.924378e-03 -3.056214e-03
## ASV12458    -2.981056e-03 -3.116063e-03 -3.256861e-03 -3.403670e-03
## ASV1636      1.657887e-03  1.734226e-03  1.813955e-03  1.897212e-03
## ASV1890     -1.394582e-03 -1.456652e-03 -1.521283e-03 -1.588561e-03
## ASV2898      2.222199e-03  2.324543e-03  2.431434e-03  2.543060e-03
## ASV8328      1.948749e-04  2.069011e-04  2.197509e-04  2.334857e-04
## ASV0709     -2.460531e-03 -2.574642e-03 -2.693896e-03 -2.818512e-03
## ASV0856      1.994986e-03  2.089679e-03  2.188849e-03  2.292704e-03
## ASV0909      5.361395e-04  5.633913e-04  5.920995e-04  6.223478e-04
## ASV0937     -1.427012e-03 -1.494020e-03 -1.564132e-03 -1.637488e-03
## ASV11390    -4.254290e-03 -4.446943e-03 -4.647859e-03 -4.857351e-03
## ASV11966     9.656659e-04  1.012034e-03  1.060641e-03  1.111597e-03
## ASV12990     7.327997e-04  7.664687e-04  8.016240e-04  8.383253e-04
## ASV14797     1.091871e-03  1.141727e-03  1.193758e-03  1.248048e-03
## ASV14904    -6.104655e-03 -6.381094e-03 -6.669390e-03 -6.969990e-03
## ASV15304     5.924973e-04  6.215318e-04  6.520213e-04  6.840410e-04
## ASV16696    -2.109127e-03 -2.204629e-03 -2.304226e-03 -2.408073e-03
## ASV1690      3.383279e-03  3.544245e-03  3.712847e-03  3.889446e-03
## ASV2029      2.424674e-03  2.536827e-03  2.654012e-03  2.776439e-03
## ASV2834      2.996593e-03  3.137060e-03  3.284004e-03  3.437714e-03
## ASV4003      2.401988e-03  2.517247e-03  2.638073e-03  2.764739e-03
## ASV4064      1.416358e-03  1.483012e-03  1.552762e-03  1.625749e-03
## ASV4294      8.213434e-04  8.615069e-04  9.036781e-04  9.479607e-04
## ASV4609      8.213326e-04  8.592908e-04  8.989464e-04  9.403700e-04
## ASV6283     -1.971653e-03 -2.060934e-03 -2.154044e-03 -2.251128e-03
## ASV6491     -2.825733e-03 -2.953677e-03 -3.087107e-03 -3.226230e-03
## ASV7453      1.276685e-03  1.338167e-03  1.402635e-03  1.470236e-03
## ASV7959      4.337690e-04  4.557887e-04  4.789802e-04  5.034099e-04
## ASV8219      2.441922e-02  2.552482e-02  2.667783e-02  2.788003e-02
## ASV8547     -2.529538e-03 -2.644054e-03 -2.763479e-03 -2.887998e-03
## ASV9319      1.048254e-03  1.097926e-03  1.149938e-03  1.204400e-03
## ASV9382     -4.949111e-03 -5.173152e-03 -5.406796e-03 -5.650407e-03
## ASV11516    -3.305308e-03 -3.454922e-03 -3.610947e-03 -3.773626e-03
## ASV14377    -2.386393e-03 -2.494402e-03 -2.607039e-03 -2.724478e-03
## ASV1867      1.772694e-03  1.856073e-03  1.943323e-03  2.034620e-03
## ASV1895      9.290050e-04  9.710956e-04  1.014987e-03  1.060747e-03
## ASV3168      1.157650e-03  1.210569e-03  1.265799e-03  1.323430e-03
## ASV4449      6.262141e-03  6.552834e-03  6.856677e-03  7.174233e-03
## ASV6596      1.247141e-03  1.307407e-03  1.370623e-03  1.436935e-03
## ASV7492     -2.896206e-04 -3.008230e-04 -3.123230e-04 -3.241143e-04
## ASV9854     -5.149018e-04 -5.379976e-04 -5.620648e-04 -5.871386e-04
## ASV6296      4.004055e-02  4.185258e-02  4.374223e-02  4.571242e-02
## ASV4201      1.325935e-04  1.411028e-04  1.502179e-04  1.599852e-04
## ASV0552      1.229406e-03  1.287114e-03  1.347490e-03  1.410654e-03
## ASV3671     -8.348556e-04 -8.733358e-04 -9.135335e-04 -9.555205e-04
## ASV3529     -2.586631e-04 -2.688155e-04 -2.792562e-04 -2.899821e-04
## ASV1060      3.222549e-04  3.375761e-04  3.536249e-04  3.704357e-04
## ASV0239     -4.620893e-04 -4.829297e-04 -5.046544e-04 -5.272958e-04
## ASV5711     -2.046529e-03 -2.140674e-03 -2.238998e-03 -2.341672e-03
## ASV4152     -2.851912e-03 -2.984921e-03 -3.124003e-03 -3.269424e-03
## ASV1461      1.485296e-03  1.552537e-03  1.622655e-03  1.695757e-03
## ASV2877      7.668769e-04  8.017886e-04  8.382120e-04  8.762053e-04
## ASV0012      1.290909e-04  1.351026e-04  1.413878e-04  1.479585e-04
## ASV9823      2.001591e-04  2.087853e-04  2.177371e-04  2.270221e-04
## ASV0008      1.381756e-04  1.445899e-04  1.512942e-04  1.583009e-04
## ASV7832     -1.675261e-03 -1.753519e-03 -1.835365e-03 -1.920958e-03
## ASV1915     -2.187132e-04 -2.286480e-04 -2.390135e-04 -2.498268e-04
## ASV0055     -1.409779e-04 -1.478661e-04 -1.550984e-04 -1.626925e-04
## ASV0032      7.352896e-05  7.674782e-05  8.009385e-05  8.357075e-05
## ASV2977     -2.370700e-03 -2.481077e-03 -2.596475e-03 -2.717114e-03
## ASV0466      1.964579e-03  2.053532e-03  2.146294e-03  2.243007e-03
## ASV3866      1.284361e-03  1.344937e-03  1.408342e-03  1.474705e-03
## ASV0040      4.679601e-04  4.898593e-04  5.127651e-04  5.367221e-04
## ASV0496     -8.684615e-05 -9.194986e-05 -9.738604e-05 -1.031785e-04
## ASV0052      3.925649e-04  4.109506e-04  4.301827e-04  4.502986e-04
## ASV3828     -1.420306e-03 -1.484494e-03 -1.551424e-03 -1.621198e-03
## ASV1930      7.166592e-04  7.495752e-04  7.839439e-04  8.198238e-04
## ASV2126      1.210928e-03  1.266968e-03  1.325523e-03  1.386701e-03
## ASV0793      1.458120e-03  1.526760e-03  1.598594e-03  1.673764e-03
## ASV0299     -2.819363e-05 -2.952809e-05 -3.092643e-05 -3.239191e-05
## ASV0208      1.060005e-03  1.109593e-03  1.161458e-03  1.215701e-03
## ASV0511     -4.544927e-04 -4.749801e-04 -4.963348e-04 -5.185880e-04
## ASV1123     -1.370286e-03 -1.432217e-03 -1.496789e-03 -1.564100e-03
## ASV0099      3.684111e-05  3.867878e-05  4.061207e-05  4.264632e-05
## ASV0752     -7.403365e-04 -7.755870e-04 -8.125139e-04 -8.511967e-04
## ASV0883      1.017910e-03  1.066272e-03  1.116924e-03  1.169974e-03
## ASV0683      1.338044e-03  1.401292e-03  1.467507e-03  1.536824e-03
## ASV4117     -2.157755e-03 -2.258589e-03 -2.364047e-03 -2.474334e-03
## ASV2172      1.510266e-04  1.576262e-04  1.644844e-04  1.716085e-04
## ASV0330     -4.010682e-04 -4.199048e-04 -4.396135e-04 -4.602338e-04
## ASV0728      2.000820e-03  2.093996e-03  2.191409e-03  2.293242e-03
## ASV0499      5.197538e-04  5.443588e-04  5.701215e-04  5.970955e-04
## ASV0120     -8.864269e-04 -9.277473e-04 -9.709507e-04 -1.016119e-03
## ASV1446      7.262040e-04  7.580893e-04  7.912451e-04  8.257098e-04
## ASV17171    -1.717485e-03 -1.797274e-03 -1.880680e-03 -1.967857e-03
## ASV0533      1.223656e-04  1.282857e-04  1.344962e-04  1.410116e-04
## ASV2495     -3.954591e-04 -4.148685e-04 -4.352581e-04 -4.566796e-04
## ASV5582      8.324277e-04  8.695049e-04  9.081097e-04  9.482933e-04
## ASV1488      3.082384e-04  3.223666e-04  3.371155e-04  3.525100e-04
## ASV0682      3.774487e-04  3.953715e-04  4.141424e-04  4.338013e-04
## ASV0068     -6.697266e-04 -7.010110e-04 -7.337274e-04 -7.679386e-04
## ASV1987     -1.629461e-03 -1.707167e-03 -1.788580e-03 -1.873877e-03
## ASV0035     -1.082561e-04 -1.139517e-04 -1.199695e-04 -1.263294e-04
## ASV7192     -1.052720e-03 -1.101221e-03 -1.151880e-03 -1.204788e-03
## ASV0873      1.816885e-04  1.772263e-04  1.713688e-04  1.639479e-04
## ASV4749      1.625891e-05  1.492311e-05  1.332791e-05  1.144329e-05
## ASV2174      7.553936e-04  7.892393e-04  8.244989e-04  8.612216e-04
## ASV1476     -7.273201e-04 -7.617676e-04 -7.978392e-04 -8.356107e-04
## ASV0740     -2.066287e-03 -2.164155e-03 -2.266632e-03 -2.373933e-03
## ASV0170     -4.106255e-04 -4.298114e-04 -4.498762e-04 -4.708587e-04
## ASV2466     -1.872382e-03 -1.959830e-03 -2.051284e-03 -2.146919e-03
## ASV1709      7.031455e-04  7.352509e-04  7.687614e-04  8.037336e-04
## ASV6170     -2.903947e-03 -3.040766e-03 -3.183960e-03 -3.333821e-03
## ASV3673      1.417996e-03  1.485146e-03  1.555457e-03  1.629077e-03
## ASV1745     -3.595700e-04 -3.769218e-04 -3.951207e-04 -4.142090e-04
##                                                                    
## (Intercept)  1.196753e-02  1.252513e-02  1.310810e-02  1.371755e-02
## ASV1236      2.403986e-03  2.513664e-03  2.628122e-03  2.747547e-03
## ASV0421      2.483719e-04  2.611882e-04  2.747046e-04  2.889624e-04
## ASV0691     -1.923220e-03 -2.007971e-03 -2.096133e-03 -2.187813e-03
## ASV0899      2.077965e-03  2.173119e-03  2.272447e-03  2.376116e-03
## ASV1004      4.805268e-03  5.025004e-03  5.254357e-03  5.493709e-03
## ASV1041     -1.979728e-03 -2.070088e-03 -2.164383e-03 -2.262765e-03
## ASV1058      3.001662e-03  3.138768e-03  3.281862e-03  3.431180e-03
## ASV12542     1.174294e-03  1.227333e-03  1.282632e-03  1.340274e-03
## ASV1294      2.791758e-03  2.919377e-03  3.052580e-03  3.191586e-03
## ASV13113     9.005123e-04  9.435306e-04  9.886093e-04  1.035848e-03
## ASV1318      2.784709e-03  2.911962e-03  3.044778e-03  3.183376e-03
## ASV2269     -4.827665e-03 -5.047963e-03 -5.277859e-03 -5.517727e-03
## ASV2542      2.300505e-03  2.408469e-03  2.521426e-03  2.639598e-03
## ASV2660     -1.925508e-03 -2.013115e-03 -2.104516e-03 -2.199855e-03
## ASV2737      6.775387e-04  7.077247e-04  7.391580e-04  7.718813e-04
## ASV2840      2.590382e-03  2.706917e-03  2.828367e-03  2.954911e-03
## ASV3053      1.320175e-02  1.379881e-02  1.442138e-02  1.507042e-02
## ASV3077      8.407660e-04  8.788578e-04  9.185845e-04  9.600079e-04
## ASV3134      1.446848e-03  1.515416e-03  1.587218e-03  1.662405e-03
## ASV3140      1.991163e-03  2.083790e-03  2.180622e-03  2.281840e-03
## ASV3579      6.823641e-04  7.154706e-04  7.502090e-04  7.866617e-04
## ASV6119     -1.321168e-03 -1.381449e-03 -1.444355e-03 -1.509990e-03
## ASV7557     -2.684630e-03 -2.807108e-03 -2.934918e-03 -3.068270e-03
## ASV8422      6.733148e-04  7.037860e-04  7.355617e-04  7.686911e-04
## ASV1086     -1.087012e-04 -1.134056e-04 -1.182914e-04 -1.233635e-04
## ASV1310      1.285409e-03  1.344113e-03  1.405380e-03  1.469309e-03
## ASV15750    -1.788984e-04 -1.868387e-04 -1.951033e-04 -2.037027e-04
## ASV16905    -5.520507e-04 -5.772361e-04 -6.035181e-04 -6.309397e-04
## ASV2033      2.299842e-03  2.408392e-03  2.522017e-03  2.640947e-03
## ASV2089      1.163621e-03  1.216735e-03  1.272166e-03  1.330002e-03
## ASV2127      3.778059e-03  3.950581e-03  4.130632e-03  4.318508e-03
## ASV2725      3.039695e-03  3.177467e-03  3.321154e-03  3.470980e-03
## ASV2804     -1.142762e-03 -1.194893e-03 -1.249294e-03 -1.306053e-03
## ASV3075      2.478885e-03  2.593581e-03  2.713432e-03  2.838656e-03
## ASV3327      3.396647e-03  3.555853e-03  3.722400e-03  3.896614e-03
## ASV3342      2.926647e-03  3.063348e-03  3.206308e-03  3.355803e-03
## ASV3532     -3.243019e-03 -3.393613e-03 -3.551020e-03 -3.715534e-03
## ASV3600      1.504822e-03  1.574864e-03  1.648092e-03  1.724641e-03
## ASV4013      2.828810e-03  2.959106e-03  3.095195e-03  3.237316e-03
## ASV4136      3.049466e-03  3.187804e-03  3.332096e-03  3.482571e-03
## ASV4195      1.166436e-02  1.219640e-02  1.275159e-02  1.333085e-02
## ASV4407     -4.506425e-03 -4.711950e-03 -4.926419e-03 -5.150179e-03
## ASV4717      8.004513e-04  8.359225e-04  8.728406e-04  9.112530e-04
## ASV6794      1.885006e-03  1.969833e-03  2.058247e-03  2.150380e-03
## ASV8324     -2.312349e-03 -2.417810e-03 -2.527860e-03 -2.642678e-03
## ASV8981     -6.750403e-05 -6.993088e-05 -7.240046e-05 -7.490828e-05
## ASV9859      7.624899e-04  7.997896e-04  8.389573e-04  8.800904e-04
## ASV0936      2.205194e-03  2.308300e-03  2.416136e-03  2.528908e-03
## ASV12683     9.867904e-07  7.999712e-07  5.835566e-07  3.344292e-07
## ASV1293      1.501148e-03  1.569534e-03  1.640889e-03  1.715329e-03
## ASV13055    -4.286224e-05 -4.433976e-05 -4.583554e-05 -4.734579e-05
## ASV17063    -1.199506e-03 -1.254189e-03 -1.311249e-03 -1.370780e-03
## ASV2228      9.781521e-04  1.022739e-03  1.069264e-03  1.117802e-03
## ASV2769      1.425367e-04  1.497819e-04  1.574129e-04  1.654517e-04
## ASV2803      1.070706e-03  1.118711e-03  1.168728e-03  1.220827e-03
## ASV2896      8.296726e-04  8.685895e-04  9.093056e-04  9.519018e-04
## ASV3062      9.846205e-04  1.031951e-03  1.081573e-03  1.133601e-03
## ASV3107      1.550723e-03  1.623182e-03  1.698962e-03  1.778210e-03
## ASV3265      2.149484e-03  2.247298e-03  2.349346e-03  2.455794e-03
## ASV3666      2.193036e-05  2.286061e-05  2.382396e-05  2.482090e-05
## ASV4497      7.352478e-04  7.689165e-04  8.040635e-04  8.407479e-04
## ASV6914     -1.033219e-04 -1.084927e-04 -1.139328e-04 -1.196570e-04
## ASV0576     -2.598861e-03 -2.714888e-03 -2.835730e-03 -2.961554e-03
## ASV0673      2.824070e-03  2.953912e-03  3.089503e-03  3.231077e-03
## ASV0772      1.307426e-03  1.367758e-03  1.430783e-03  1.496614e-03
## ASV0862      9.820325e-05  1.046094e-04  1.114782e-04  1.188456e-04
## ASV0898      9.973832e-04  1.044646e-03  1.094136e-03  1.145955e-03
## ASV0910      1.159987e-03  1.214352e-03  1.271223e-03  1.330713e-03
## ASV0964     -9.781496e-04 -1.022123e-03 -1.067948e-03 -1.115693e-03
## ASV10059     8.158250e-04  8.547122e-04  8.954533e-04  9.381367e-04
## ASV10263    -1.826721e-03 -1.910052e-03 -1.997010e-03 -2.087739e-03
## ASV1088      2.075621e-03  2.172382e-03  2.273559e-03  2.379346e-03
## ASV1101      2.614162e-03  2.733239e-03  2.857483e-03  2.987094e-03
## ASV1183      6.822909e-04  7.139705e-04  7.470829e-04  7.816895e-04
## ASV11956     6.791751e-04  7.094309e-04  7.409359e-04  7.737329e-04
## ASV12774     4.703380e-05  4.861839e-05  5.021796e-05  5.182782e-05
## ASV1321      2.986469e-03  3.127012e-03  3.274089e-03  3.427997e-03
## ASV13793    -1.259501e-03 -1.316954e-03 -1.376908e-03 -1.439460e-03
## ASV14482     8.348411e-05  8.706523e-05  9.078197e-05  9.463792e-05
## ASV15483     5.091000e-04  5.329339e-04  5.578639e-04  5.839386e-04
## ASV2062      2.401200e-03  2.511643e-03  2.626984e-03  2.747423e-03
## ASV2132      1.939328e-03  2.029973e-03  2.124773e-03  2.223911e-03
## ASV2413      1.865311e-03  1.950512e-03  2.039434e-03  2.132226e-03
## ASV2490      5.786671e-03  6.047992e-03  6.320444e-03  6.604439e-03
## ASV2594      7.096567e-04  7.426130e-04  7.770627e-04  8.130700e-04
## ASV2822     -3.323675e-03 -3.475324e-03 -3.633577e-03 -3.798694e-03
## ASV2863      3.549021e-03  3.710058e-03  3.878029e-03  4.053200e-03
## ASV2910      1.295123e-03  1.354138e-03  1.415717e-03  1.479960e-03
## ASV2980      1.434420e-03  1.500507e-03  1.569534e-03  1.641622e-03
## ASV3307      2.644490e-03  2.765121e-03  2.891004e-03  3.022345e-03
## ASV3474      1.703910e-03  1.784521e-03  1.868917e-03  1.957276e-03
## ASV3502      1.815112e-03  1.899246e-03  1.987171e-03  2.079049e-03
## ASV4236      2.725898e-03  2.848669e-03  2.976635e-03  3.109985e-03
## ASV4842     -2.829113e-04 -2.963439e-04 -3.104081e-04 -3.251327e-04
## ASV4894     -1.259701e-03 -1.317173e-03 -1.377149e-03 -1.439725e-03
## ASV5290      9.853174e-04  1.031293e-03  1.079369e-03  1.129636e-03
## ASV5501      6.054253e-04  6.334567e-04  6.627503e-04  6.933598e-04
## ASV5795      6.613909e-04  6.922987e-04  7.246226e-04  7.584250e-04
## ASV5987     -3.518517e-03 -3.679062e-03 -3.846600e-03 -4.021406e-03
## ASV6267     -3.964471e-03 -4.145343e-03 -4.334092e-03 -4.531026e-03
## ASV6862      1.602156e-03  1.674530e-03  1.749990e-03  1.828652e-03
## ASV7145      7.119284e-04  7.437718e-04  7.769454e-04  8.114966e-04
## ASV7673     -1.259647e-03 -1.317115e-03 -1.377085e-03 -1.439656e-03
## ASV7789      5.961561e-04  6.251883e-04  6.556618e-04  6.876504e-04
## ASV7809      3.159968e-05  3.375381e-05  3.606957e-05  3.855980e-05
## ASV8002     -1.590871e-03 -1.663449e-03 -1.739186e-03 -1.818208e-03
## ASV8205      6.568644e-04  6.874390e-04  7.194037e-04  7.528189e-04
## ASV9155     -4.075128e-04 -4.259076e-04 -4.450847e-04 -4.650726e-04
## ASV9221      1.441784e-04  1.519963e-04  1.602740e-04  1.690411e-04
## ASV9311     -2.552001e-03 -2.668418e-03 -2.789904e-03 -2.916657e-03
## ASV9557     -1.744016e-03 -1.823565e-03 -1.906577e-03 -1.993188e-03
## ASV9936     -3.516876e-03 -3.677271e-03 -3.844646e-03 -4.019275e-03
## ASV1445      2.105142e-03  2.203197e-03  2.305715e-03  2.412891e-03
## ASV4232      7.834504e-04  8.207697e-04  8.598678e-04  9.008297e-04
## ASV6479      2.603413e-04  2.739866e-04  2.883955e-04  3.036144e-04
## ASV0142     -1.520078e-03 -1.589152e-03 -1.661208e-03 -1.736362e-03
## ASV0378      6.670631e-04  6.988706e-04  7.321956e-04  7.671103e-04
## ASV1122      2.032379e-03  2.127374e-03  2.226726e-03  2.330624e-03
## ASV0123     -1.343274e-03 -1.404255e-03 -1.467864e-03 -1.534200e-03
## ASV2064      6.977882e-04  7.288150e-04  7.611154e-04  7.947318e-04
## ASV4459     -1.009164e-04 -1.051953e-04 -1.096305e-04 -1.142254e-04
## ASV0448      5.330903e-04  5.585323e-04  5.851900e-04  6.131213e-04
## ASV0397      1.204707e-03  1.260388e-03  1.318563e-03  1.379337e-03
## ASV0485      1.407048e-03  1.471637e-03  1.539078e-03  1.609486e-03
## ASV1566      2.064579e-03  2.159881e-03  2.259438e-03  2.363429e-03
## ASV1365      1.755154e-03  1.836682e-03  1.921898e-03  2.010960e-03
## ASV1065      2.496885e-03  2.612693e-03  2.733725e-03  2.860206e-03
## ASV0722     -1.284986e-04 -1.345694e-04 -1.409253e-04 -1.475793e-04
## ASV12660    -1.458379e-03 -1.524408e-03 -1.593268e-03 -1.665066e-03
## ASV0223      3.881326e-04  4.059813e-04  4.246216e-04  4.440861e-04
## ASV0229      5.848604e-04  6.122208e-04  6.408384e-04  6.707689e-04
## ASV0877      2.556271e-04  2.669612e-04  2.787551e-04  2.910235e-04
## ASV0983      1.399441e-03  1.463514e-03  1.530399e-03  1.600209e-03
## ASV0626      1.303171e-04  1.375734e-04  1.452700e-04  1.534361e-04
## ASV4146      6.888097e-05  7.205065e-05  7.535854e-05  7.880972e-05
## ASV4175     -1.700367e-03 -1.779735e-03 -1.862732e-03 -1.949515e-03
## ASV2082     -7.278193e-04 -7.641112e-04 -8.022827e-04 -8.424371e-04
## ASV2272      8.114806e-04  8.492348e-04  8.887049e-04  9.299650e-04
## ASV2245     -1.211681e-03 -1.268410e-03 -1.327748e-03 -1.389810e-03
## ASV0590     -6.751591e-04 -7.095728e-04 -7.458325e-04 -7.840444e-04
## ASV0217      3.577423e-05  3.916687e-05  4.287513e-05  4.692751e-05
## ASV0416      9.602671e-04  1.002712e-03  1.046876e-03  1.092814e-03
## ASV1056      1.164871e-03  1.219836e-03  1.277369e-03  1.337588e-03
## ASV7777     -1.658869e-03 -1.736043e-03 -1.816722e-03 -1.901059e-03
## ASV0455      2.986088e-04  3.124483e-04  3.269111e-04  3.420237e-04
## ASV0604      7.629778e-04  7.992255e-04  8.371891e-04  8.769492e-04
## ASV6100     -1.137339e-03 -1.190603e-03 -1.246321e-03 -1.304601e-03
## ASV11359    -2.456573e-03 -2.570919e-03 -2.690461e-03 -2.815425e-03
## ASV6604      3.362166e-04  3.521455e-04  3.688244e-04  3.862883e-04
## ASV5004     -8.765702e-04 -9.171904e-04 -9.596408e-04 -1.003999e-03
## ASV1483     -3.785528e-04 -3.960371e-04 -4.143035e-04 -4.333844e-04
## ASV9773     -1.104328e-03 -1.155863e-03 -1.209755e-03 -1.266106e-03
## ASV4059     -1.842780e-05 -1.797928e-05 -1.738785e-05 -1.663596e-05
## ASV1193      1.343231e-03  1.405364e-03  1.470283e-03  1.538107e-03
## ASV4610     -2.406535e-04 -2.499270e-04 -2.594461e-04 -2.692056e-04
## ASV0742     -1.512971e-04 -1.567885e-04 -1.623853e-04 -1.680789e-04
## ASV1502     -4.548049e-05 -4.853328e-05 -5.181254e-05 -5.533618e-05
## ASV0195      4.170300e-05  4.304391e-05  4.439051e-05  4.573806e-05
## ASV1213      9.696473e-04  1.013028e-03  1.058218e-03  1.105280e-03
## ASV1648     -1.022309e-03 -1.070131e-03 -1.120150e-03 -1.172465e-03
## ASV6984     -9.561274e-04 -1.000874e-03 -1.047679e-03 -1.096635e-03
## ASV0396     -6.485032e-05 -6.719306e-05 -6.958018e-05 -7.200806e-05
## ASV4297      1.396711e-03  1.459810e-03  1.525599e-03  1.594177e-03
## ASV2622      2.149666e-03  2.247826e-03  2.350271e-03  2.457169e-03
## ASV3512      7.981339e-04  8.370107e-04  8.778191e-04  9.206582e-04
## ASV2411      1.428675e-03  1.496184e-03  1.566857e-03  1.640841e-03
## ASV2291     -5.785652e-04 -6.084029e-04 -6.398696e-04 -6.730612e-04
## ASV0807      1.977871e-03  2.069393e-03  2.165023e-03  2.264934e-03
## ASV1292      4.936767e-04  5.154873e-04  5.381809e-04  5.617858e-04
## ASV1035      1.838095e-03  1.921564e-03  2.008635e-03  2.099448e-03
## ASV0070      6.018618e-06  6.912852e-06  7.905906e-06  9.007529e-06
## ASV0255      1.771712e-04  1.850344e-04  1.932184e-04  2.017336e-04
## ASV0057     -5.108764e-04 -5.337593e-04 -5.575982e-04 -5.824267e-04
## ASV0077     -1.120193e-04 -1.168072e-04 -1.217726e-04 -1.269196e-04
## ASV0625      1.061436e-03  1.109458e-03  1.159533e-03  1.211738e-03
## ASV2464      7.237113e-03  7.563454e-03  7.903667e-03  8.258266e-03
## ASV1315      1.857641e-03  1.945668e-03  2.037845e-03  2.134363e-03
## ASV2673      1.592486e-03  1.668011e-03  1.747101e-03  1.829923e-03
## ASV2161      6.744341e-04  7.063501e-04  7.397669e-04  7.747542e-04
## ASV0337     -3.895606e-04 -4.077728e-04 -4.268200e-04 -4.467392e-04
## ASV7680     -2.539467e-03 -2.658372e-03 -2.782749e-03 -2.912841e-03
## ASV0611      1.417516e-03  1.483936e-03  1.553419e-03  1.626099e-03
## ASV3118     -1.456468e-03 -1.525750e-03 -1.598322e-03 -1.674339e-03
## ASV1284      5.914061e-04  6.147134e-04  6.386835e-04  6.633080e-04
## ASV0889      1.089062e-03  1.138948e-03  1.191028e-03  1.245389e-03
## ASV4649     -5.405040e-04 -5.656097e-04 -5.918520e-04 -6.192795e-04
## ASV1108     -1.083930e-03 -1.135874e-03 -1.190321e-03 -1.247392e-03
## ASV0738      5.851737e-04  6.141560e-04  6.446208e-04  6.766477e-04
## ASV0473     -1.130709e-04 -1.190921e-04 -1.254561e-04 -1.321840e-04
## ASV0598     -2.940813e-04 -3.089855e-04 -3.246829e-04 -3.412188e-04
## ASV0429      8.127507e-04  8.496932e-04  8.882304e-04  9.284233e-04
## ASV1549      1.468507e-03  1.538210e-03  1.611209e-03  1.687658e-03
## ASV1203      1.182366e-03  1.236674e-03  1.293383e-03  1.352589e-03
## ASV4532      5.507822e-05  5.731226e-05  5.961816e-05  6.199646e-05
## ASV0274      1.980907e-04  2.077383e-04  2.178639e-04  2.284915e-04
## ASV0163     -9.236390e-04 -9.653242e-04 -1.008783e-03 -1.054081e-03
## ASV1298      1.050935e-04  1.095482e-04  1.141664e-04  1.189519e-04
## ASV9424     -1.965177e-03 -2.057424e-03 -2.153939e-03 -2.254915e-03
## ASV0412      2.056260e-03  2.150348e-03  2.248564e-03  2.351070e-03
## ASV0284      4.434491e-04  4.627947e-04  4.828986e-04  5.037827e-04
## ASV0620     -4.000308e-04 -4.198656e-04 -4.407161e-04 -4.626370e-04
## ASV0153     -1.963474e-03 -2.056667e-03 -2.154265e-03 -2.256475e-03
## ASV0498      6.984691e-04  7.312187e-04  7.654780e-04  8.013141e-04
## ASV0097      3.858280e-04  4.041306e-04  4.232977e-04  4.433700e-04
## ASV0104     -2.776611e-03 -2.904764e-03 -3.038639e-03 -3.178472e-03
## ASV1282      9.685169e-04  1.012442e-03  1.058253e-03  1.106022e-03
## ASV3883     -7.378608e-04 -7.736341e-04 -8.111669e-04 -8.505475e-04
## ASV0801      3.727659e-04  3.902250e-04  4.084874e-04  4.275886e-04
## ASV1611     -1.755665e-03 -1.838526e-03 -1.925262e-03 -2.016050e-03
## ASV0227     -3.024098e-04 -3.177530e-04 -3.339119e-04 -3.509325e-04
## ASV0833      6.009457e-04  6.290255e-04  6.583912e-04  6.890990e-04
## ASV0718      2.693247e-03  2.818716e-03  2.949900e-03  3.087047e-03
## ASV1139      3.700784e-04  3.856711e-04  4.018185e-04  4.185301e-04
## ASV0766     -3.663837e-04 -3.841895e-04 -4.028742e-04 -4.224822e-04
## ASV2091      2.228109e-03  2.328988e-03  2.434187e-03  2.543868e-03
## ASV1238     -1.991875e-03 -2.085445e-03 -2.183353e-03 -2.285795e-03
## ASV9193     -1.730261e-04 -1.824740e-04 -1.924838e-04 -2.030925e-04
## ASV0290      2.995313e-04  3.124506e-04  3.258628e-04  3.397805e-04
## ASV0231      8.094491e-04  8.464902e-04  8.851555e-04  9.255096e-04
## ASV0185      4.497687e-04  4.719859e-04  4.953345e-04  5.198747e-04
## ASV2330      9.387948e-04  9.809477e-04  1.024872e-03  1.070631e-03
## ASV3119     -4.082843e-04 -4.283778e-04 -4.494875e-04 -4.716670e-04
## ASV2368     -1.015188e-03 -1.063407e-03 -1.113910e-03 -1.166807e-03
## ASV0122     -5.014742e-04 -5.245397e-04 -5.486278e-04 -5.737805e-04
## ASV1044      1.264771e-03  1.324476e-03  1.386974e-03  1.452394e-03
## ASV0160     -5.461366e-04 -5.706836e-04 -5.962649e-04 -6.229177e-04
## ASV0326      1.407609e-04  1.473511e-04  1.542440e-04  1.614530e-04
## ASV1388      2.597819e-03  2.717587e-03  2.842689e-03  2.973346e-03
## ASV0792      1.942372e-03  2.030833e-03  2.123133e-03  2.219421e-03
## ASV0036     -5.887890e-04 -6.167530e-04 -6.460401e-04 -6.767123e-04
## ASV2125      1.853142e-03  1.938864e-03  2.028431e-03  2.122006e-03
## ASV1075     -2.794480e-05 -2.922954e-05 -3.057181e-05 -3.197410e-05
## ASV0390      9.727685e-04  1.018923e-03  1.067259e-03  1.117880e-03
## ASV3790     -1.393846e-03 -1.459065e-03 -1.527281e-03 -1.598627e-03
## ASV1535     -3.902929e-04 -4.094111e-04 -4.294882e-04 -4.505742e-04
## ASV0263      1.714806e-03  1.794481e-03  1.877765e-03  1.964811e-03
## ASV0675      2.557283e-03  2.677521e-03  2.803339e-03  2.934989e-03
## ASV3348      2.035503e-04  2.133954e-04  2.237227e-04  2.345562e-04
## ASV0058     -7.691491e-04 -8.045506e-04 -8.415234e-04 -8.801320e-04
## ASV4142      1.086984e-03  1.136445e-03  1.188045e-03  1.241867e-03
## ASV0059     -6.210177e-04 -6.494980e-04 -6.792326e-04 -7.102721e-04
## ASV0013     -1.095453e-03 -1.146302e-03 -1.199450e-03 -1.254994e-03
## ASV0033     -5.124618e-04 -5.367521e-04 -5.621872e-04 -5.888206e-04
## ASV4354     -6.451277e-04 -6.750724e-04 -7.063726e-04 -7.390865e-04
## ASV0022     -4.329264e-04 -4.534333e-04 -4.749058e-04 -4.973885e-04
## ASV0134     -4.069674e-04 -4.265946e-04 -4.471783e-04 -4.687661e-04
## ASV0415      6.210936e-05  6.535434e-05  6.877892e-05  7.239371e-05
## ASV10103    -2.415888e-03 -2.529509e-03 -2.648406e-03 -2.772817e-03
## ASV1613      1.840638e-03  1.924533e-03  2.012074e-03  2.103401e-03
## ASV0135     -2.393823e-04 -2.500979e-04 -2.612604e-04 -2.728853e-04
## ASV0469     -2.365317e-03 -2.473838e-03 -2.587146e-03 -2.705435e-03
## ASV0471      1.430029e-03  1.496314e-03  1.565586e-03  1.637971e-03
## ASV0451     -2.174834e-04 -2.287155e-04 -2.405622e-04 -2.530597e-04
## ASV0747      8.100115e-04  8.478232e-04  8.873634e-04  9.287075e-04
## ASV1314     -8.032134e-04 -8.414152e-04 -8.814316e-04 -9.233484e-04
## ASV0425     -2.948474e-03 -3.082361e-03 -3.222020e-03 -3.367671e-03
## ASV0559     -7.210880e-04 -7.543803e-04 -7.891629e-04 -8.254987e-04
## ASV0148     -1.739575e-04 -1.812628e-04 -1.888252e-04 -1.966487e-04
## ASV0129      1.467933e-04  1.550584e-04  1.638351e-04  1.731583e-04
## ASV1072      2.001265e-04  2.089153e-04  2.180534e-04  2.275514e-04
## ASV2390      1.520433e-03  1.588830e-03  1.660111e-03  1.734380e-03
## ASV0548      9.850681e-04  1.030656e-03  1.078291e-03  1.128060e-03
## ASV0168     -5.089502e-04 -5.322798e-04 -5.566361e-04 -5.820605e-04
## ASV0066     -5.716590e-04 -5.979845e-04 -6.254795e-04 -6.541920e-04
## ASV0468     -3.006365e-04 -3.146241e-04 -3.292472e-04 -3.445333e-04
## ASV0172     -1.773104e-04 -1.850674e-04 -1.931300e-04 -2.015071e-04
## ASV0236     -5.933642e-05 -6.020910e-05 -6.094350e-05 -6.151706e-05
## ASV0250      7.776985e-04  8.154474e-04  8.550595e-04  8.966294e-04
## ASV0338      3.744414e-04  3.922439e-04  4.108890e-04  4.304158e-04
## ASV0450     -6.505464e-05 -6.849525e-05 -7.213092e-05 -7.597367e-05
## ASV0377      7.149873e-04  7.478526e-04  7.821729e-04  8.180074e-04
## ASV1022     -3.126858e-05 -3.265247e-05 -3.409169e-05 -3.558780e-05
## ASV6174     -1.274858e-05 -1.352560e-05 -1.435637e-05 -1.524507e-05
## ASV0786     -8.729808e-05 -9.216249e-05 -9.732180e-05 -1.027954e-04
## ASV0053     -7.670590e-04 -8.027596e-04 -8.400825e-04 -8.790976e-04
## ASV0697     -4.733746e-04 -4.949295e-04 -5.174200e-04 -5.408824e-04
## ASV0785      9.901382e-04  1.035671e-03  1.083220e-03  1.132870e-03
## ASV1967     -9.869944e-04 -1.032148e-03 -1.079283e-03 -1.128478e-03
## ASV0385      3.226622e-04  3.380850e-04  3.542460e-04  3.711804e-04
## ASV0295      4.982043e-05  5.271102e-05  5.578716e-05  5.906198e-05
## ASV0072     -7.730307e-04 -8.083334e-04 -8.451763e-04 -8.836198e-04
## ASV0157     -1.101082e-04 -1.143567e-04 -1.187151e-04 -1.231801e-04
## ASV0501      1.654228e-03  1.731357e-03  1.812004e-03  1.896323e-03
## ASV10729    -2.074014e-03 -2.171060e-03 -2.272565e-03 -2.378728e-03
## ASV1470      1.088204e-03  1.136982e-03  1.187801e-03  1.240733e-03
## ASV0050     -1.809227e-03 -1.892558e-03 -1.979593e-03 -2.070484e-03
## ASV0411     -4.011561e-04 -4.201245e-04 -4.399830e-04 -4.607726e-04
## ASV0549      6.474920e-04  6.779230e-04  7.097647e-04  7.430808e-04
## ASV0184      2.194267e-04  2.295275e-04  2.400776e-04  2.510956e-04
## ASV0705      4.364912e-04  4.564238e-04  4.772259e-04  4.989316e-04
## ASV1715      9.121442e-04  9.545587e-04  9.988970e-04  1.045242e-03
## ASV0603      1.406762e-04  1.473133e-04  1.542615e-04  1.615351e-04
## ASV0826      1.546996e-03  1.618446e-03  1.693093e-03  1.771069e-03
## ASV0034     -4.988465e-04 -5.216596e-04 -5.454713e-04 -5.703210e-04
## ASV0838      3.699113e-04  3.850856e-04  4.007544e-04  4.169205e-04
## ASV0614     -4.238765e-04 -4.434304e-04 -4.638572e-04 -4.851929e-04
## ASV0014     -1.120986e-03 -1.172867e-03 -1.227078e-03 -1.283717e-03
## ASV0585      1.469100e-04  1.521608e-04  1.575012e-04  1.629213e-04
## ASV0016     -1.171045e-03 -1.225242e-03 -1.281872e-03 -1.341040e-03
## ASV5394     -8.734290e-04 -9.141601e-04 -9.567498e-04 -1.001279e-03
## ASV0666      1.937428e-03  2.025584e-03  2.117557e-03  2.213496e-03
## ASV2085      4.792012e-04  4.987894e-04  5.190140e-04  5.398789e-04
## ASV0003     -7.988191e-04 -8.357687e-04 -8.743759e-04 -9.147103e-04
## ASV0346      3.936771e-04  4.124258e-04  4.320657e-04  4.526390e-04
## ASV0267     -1.092678e-05 -1.092346e-05 -1.087136e-05 -1.076380e-05
## ASV0353      6.298023e-04  6.595149e-04  6.906157e-04  7.231683e-04
## ASV2419      1.725128e-03  1.804548e-03  1.887496e-03  1.974118e-03
## ASV0447      9.220711e-04  9.656660e-04  1.011306e-03  1.059084e-03
## ASV0654      1.385541e-03  1.449737e-03  1.516822e-03  1.586919e-03
## ASV0151      1.757367e-04  1.844861e-04  1.936876e-04  2.033657e-04
## ASV0065     -5.383556e-04 -5.631538e-04 -5.890548e-04 -6.161039e-04
## ASV0527      1.320965e-03  1.381996e-03  1.445758e-03  1.512366e-03
## ASV4055     -2.020366e-04 -2.118188e-04 -2.220827e-04 -2.328527e-04
## ASV0166     -6.706669e-04 -7.011837e-04 -7.330221e-04 -7.662330e-04
## ASV0417     -2.789738e-04 -2.913671e-04 -3.042682e-04 -3.176938e-04
## ASV0078     -3.961800e-04 -4.142911e-04 -4.331940e-04 -4.529201e-04
## ASV0322     -7.892033e-05 -8.211945e-05 -8.541694e-05 -8.881228e-05
## ASV0156     -9.273755e-04 -9.707575e-04 -1.016133e-03 -1.063590e-03
## ASV0648     -2.009424e-03 -2.103722e-03 -2.202379e-03 -2.305590e-03
## ASV0407     -1.490446e-04 -1.561455e-04 -1.635849e-04 -1.713789e-04
## ASV2030     -3.409618e-04 -3.565206e-04 -3.727619e-04 -3.897135e-04
## ASV0300      2.374706e-04  2.487748e-04  2.606164e-04  2.730207e-04
## ASV1150      5.118832e-05  5.377377e-05  5.649557e-05  5.936133e-05
## ASV0958      7.331343e-04  7.680665e-04  8.046636e-04  8.430049e-04
## ASV0216     -8.332672e-04 -8.714858e-04 -9.113905e-04 -9.530498e-04
## ASV0446      1.238054e-03  1.296177e-03  1.356989e-03  1.420608e-03
## ASV0367     -8.151679e-04 -8.531664e-04 -8.928975e-04 -9.344367e-04
## ASV0200     -4.851962e-04 -5.077952e-04 -5.314228e-04 -5.561235e-04
## ASV0334     -2.777835e-04 -2.897404e-04 -3.021507e-04 -3.150261e-04
## ASV1311      3.308346e-04  3.454331e-04  3.606200e-04  3.764136e-04
## ASV0458      4.916639e-04  5.131728e-04  5.355321e-04  5.587670e-04
## ASV1371      7.379345e-05  7.741248e-05  8.121276e-05  8.520361e-05
## ASV0418      1.101038e-03  1.150977e-03  1.203064e-03  1.257381e-03
## ASV0004      1.599818e-04  1.672145e-04  1.747559e-04  1.826177e-04
## ASV1943      3.152376e-03  3.288935e-03  3.430782e-03  3.578064e-03
## ASV1495     -1.954383e-04 -2.059590e-04 -2.170924e-04 -2.288777e-04
## ASV0901     -9.089189e-04 -9.517321e-04 -9.965403e-04 -1.043434e-03
## ASV0628      5.007451e-04  5.231430e-04  5.464731e-04  5.707677e-04
## ASV0400      3.005742e-04  3.142841e-04  3.285903e-04  3.435159e-04
## ASV0116     -2.675349e-04 -2.801206e-04 -2.932910e-04 -3.070728e-04
## ASV0788      2.362286e-03  2.473585e-03  2.590072e-03  2.711984e-03
## ASV0117      1.718841e-04  1.801317e-04  1.887775e-04  1.978408e-04
## ASV3137     -5.653488e-05 -5.911429e-05 -6.180607e-05 -6.461463e-05
## ASV0001      1.721539e-04  1.799122e-04  1.879994e-04  1.964274e-04
## ASV1651      4.886588e-04  5.108030e-04  5.338976e-04  5.579785e-04
## ASV1692      1.968820e-03  2.061487e-03  2.158465e-03  2.259947e-03
## ASV0660      7.307483e-04  7.632380e-04  7.970603e-04  8.322591e-04
## ASV0508      3.707432e-05  3.869363e-05  4.037678e-05  4.212564e-05
## ASV1660     -3.871190e-04 -4.060056e-04 -4.258312e-04 -4.466435e-04
## ASV0233      6.128107e-04  6.413314e-04  6.711485e-04  7.023181e-04
## ASV1343     -1.122720e-03 -1.175462e-03 -1.230648e-03 -1.288388e-03
## ASV0209      5.752706e-04  6.012282e-04  6.282890e-04  6.564937e-04
## ASV0193     -6.696585e-04 -7.000073e-04 -7.316584e-04 -7.646609e-04
## ASV0357      2.410262e-04  2.530047e-04  2.656006e-04  2.788475e-04
## ASV0198      5.038788e-04  5.270212e-04  5.511867e-04  5.764167e-04
## ASV0007      1.528888e-04  1.597188e-04  1.668325e-04  1.742396e-04
## ASV1772     -2.292775e-04 -2.394142e-04 -2.499590e-04 -2.609244e-04
## ASV0009      1.271335e-04  1.327592e-04  1.386133e-04  1.447033e-04
## ASV0006     -1.319137e-04 -1.382219e-04 -1.448326e-04 -1.517606e-04
## ASV0011     -4.638566e-04 -4.855925e-04 -5.083301e-04 -5.321140e-04
## ASV0015      9.610766e-05  1.003597e-04  1.047842e-04  1.093867e-04
## ASV0017      1.082262e-04  1.130168e-04  1.180021e-04  1.231884e-04
## ASV0235     -4.275150e-04 -4.476240e-04 -4.686666e-04 -4.906848e-04
## ASV0382      3.345452e-04  3.502964e-04  3.667791e-04  3.840260e-04
## ASV2357      1.398236e-03  1.463694e-03  1.532163e-03  1.603777e-03
## ASV0567     -2.699746e-04 -2.826674e-04 -2.959503e-04 -3.098499e-04
## ASV0165      2.332729e-04  2.441961e-04  2.556218e-04  2.675723e-04
## ASV0005      3.412272e-04  3.570141e-04  3.735093e-04  3.907426e-04
## ASV0384     -4.354406e-05 -4.512312e-05 -4.673144e-05 -4.836625e-05
## ASV0002      6.463996e-05  6.757511e-05  7.063696e-05  7.383037e-05
## ASV3017      1.831337e-03  1.914417e-03  2.001071e-03  2.091433e-03
## ASV0091     -4.616583e-05 -4.827486e-05 -5.047637e-05 -5.277413e-05
## ASV0186     -6.862744e-04 -7.181289e-04 -7.514224e-04 -7.862163e-04
## ASV0370      3.665726e-04  3.834118e-04  4.009949e-04  4.193522e-04
## ASV0018      4.366099e-04  4.568453e-04  4.779921e-04  5.000888e-04
## ASV1377      4.427140e-03  4.628919e-03  4.839468e-03  5.059129e-03
## ASV0019      4.578794e-04  4.791116e-04  5.013011e-04  5.244884e-04
## ASV0023     -2.832371e-04 -2.965759e-04 -3.105355e-04 -3.251442e-04
## ASV2194      4.533420e-04  4.748199e-04  4.973104e-04  5.208609e-04
## ASV1155      1.855260e-03  1.939554e-03  2.027495e-03  2.119226e-03
## ASV0510     -5.056032e-04 -5.280366e-04 -5.513852e-04 -5.756788e-04
## ASV2371     -1.116733e-03 -1.167516e-03 -1.220498e-03 -1.275766e-03
## ASV0024     -3.531248e-04 -3.697247e-04 -3.870945e-04 -4.052689e-04
## ASV2452      1.134230e-03  1.185009e-03  1.237907e-03  1.292997e-03
## ASV2332     -3.195871e-03 -3.341951e-03 -3.494430e-03 -3.653564e-03
## ASV2591      7.924581e-04  8.317450e-04  8.730333e-04  9.164284e-04
## ASV0521      7.178742e-04  7.515889e-04  7.868647e-04  8.237718e-04
## ASV5542      6.864962e-04  7.188091e-04  7.526212e-04  7.879998e-04
## ASV0336     -7.903088e-05 -8.326431e-05 -8.774172e-05 -9.247839e-05
## ASV10102     1.269952e-03  1.329588e-03  1.391984e-03  1.457262e-03
## ASV16823    -2.021492e-03 -2.112189e-03 -2.206699e-03 -2.305162e-03
## ASV3104      1.045850e-02  1.092768e-02  1.141658e-02  1.192592e-02
## ASV0781      1.430244e-03  1.496449e-03  1.565629e-03  1.637910e-03
## ASV10899     8.007792e-04  8.404902e-04  8.822330e-04  9.261164e-04
## ASV11222    -3.557492e-03 -3.717074e-03 -3.883366e-03 -4.056609e-03
## ASV11327    -3.193651e-03 -3.336896e-03 -3.486162e-03 -3.641666e-03
## ASV12458    -3.556716e-03 -3.716227e-03 -3.882442e-03 -4.055601e-03
## ASV1636      1.984142e-03  2.074891e-03  2.169614e-03  2.268467e-03
## ASV1890     -1.658576e-03 -1.731417e-03 -1.807175e-03 -1.885940e-03
## ASV2898      2.659614e-03  2.781295e-03  2.908309e-03  3.040868e-03
## ASV8328      2.481714e-04  2.638794e-04  2.806862e-04  2.986744e-04
## ASV0709     -2.948715e-03 -3.084739e-03 -3.226826e-03 -3.375226e-03
## ASV0856      2.401464e-03  2.515358e-03  2.634625e-03  2.759515e-03
## ASV0909      6.542247e-04  6.878246e-04  7.232474e-04  7.605995e-04
## ASV0937     -1.714236e-03 -1.794526e-03 -1.878518e-03 -1.966377e-03
## ASV11390    -5.075740e-03 -5.303356e-03 -5.540534e-03 -5.787619e-03
## ASV11966     1.165017e-03  1.221019e-03  1.279729e-03  1.341280e-03
## ASV12990     8.766343e-04  9.166143e-04  9.583308e-04  1.001851e-03
## ASV14797     1.304685e-03  1.363760e-03  1.425364e-03  1.489594e-03
## ASV14904    -7.283357e-03 -7.609961e-03 -7.950286e-03 -8.304826e-03
## ASV15304     7.176701e-04  7.529923e-04  7.900954e-04  8.290721e-04
## ASV16696    -2.516330e-03 -2.629160e-03 -2.746728e-03 -2.869207e-03
## ASV1690      4.074417e-03  4.268152e-03  4.471061e-03  4.683573e-03
## ASV2029      2.904327e-03  3.037904e-03  3.177402e-03  3.323066e-03
## ASV2834      3.598490e-03  3.766645e-03  3.942505e-03  4.126408e-03
## ASV4003      2.897528e-03  3.036741e-03  3.182692e-03  3.335711e-03
## ASV4064      1.702118e-03  1.782023e-03  1.865621e-03  1.953077e-03
## ASV4294      9.944643e-04  1.043304e-03  1.094602e-03  1.148486e-03
## ASV4609      9.836345e-04  1.028815e-03  1.075990e-03  1.125239e-03
## ASV6283     -2.352336e-03 -2.457818e-03 -2.567732e-03 -2.682238e-03
## ASV6491     -3.371261e-03 -3.522417e-03 -3.679921e-03 -3.844003e-03
## ASV7453      1.541123e-03  1.615459e-03  1.693413e-03  1.775162e-03
## ASV7959      5.291484e-04  5.562701e-04  5.848545e-04  6.149854e-04
## ASV8219      2.913327e-02  3.043943e-02  3.180045e-02  3.321830e-02
## ASV8547     -3.017803e-03 -3.153088e-03 -3.294054e-03 -3.440904e-03
## ASV9319      1.261424e-03  1.321129e-03  1.383640e-03  1.449086e-03
## ASV9382     -5.904356e-03 -6.169025e-03 -6.444806e-03 -6.732098e-03
## ASV11516    -3.943207e-03 -4.119946e-03 -4.304102e-03 -4.495944e-03
## ASV14377    -2.846899e-03 -2.974485e-03 -3.107425e-03 -3.245911e-03
## ASV1867      2.130145e-03  2.230090e-03  2.334651e-03  2.444035e-03
## ASV1895      1.108443e-03  1.158144e-03  1.209923e-03  1.263851e-03
## ASV3168      1.383556e-03  1.446272e-03  1.511677e-03  1.579870e-03
## ASV4449      7.506089e-03  7.852851e-03  8.215150e-03  8.593640e-03
## ASV6596      1.506500e-03  1.579479e-03  1.656044e-03  1.736375e-03
## ASV7492     -3.361882e-04 -3.485342e-04 -3.611391e-04 -3.739870e-04
## ASV9854     -6.132551e-04 -6.404509e-04 -6.687636e-04 -6.982313e-04
## ASV6296      4.776617e-02  4.990656e-02  5.213673e-02  5.445991e-02
## ASV4201      1.704551e-04  1.816816e-04  1.937230e-04  2.066425e-04
## ASV0552      1.476731e-03  1.545850e-03  1.618147e-03  1.693762e-03
## ASV3671     -9.993714e-04 -1.045163e-03 -1.092976e-03 -1.142893e-03
## ASV3529     -3.009888e-04 -3.122700e-04 -3.238177e-04 -3.356220e-04
## ASV1060      3.880445e-04  4.064893e-04  4.258096e-04  4.460470e-04
## ASV0239     -5.508869e-04 -5.754615e-04 -6.010539e-04 -6.276991e-04
## ASV5711     -2.448875e-03 -2.560790e-03 -2.677607e-03 -2.799523e-03
## ASV4152     -3.421461e-03 -3.580399e-03 -3.746537e-03 -3.920185e-03
## ASV1461      1.771953e-03  1.851355e-03  1.934079e-03  2.020241e-03
## ASV2877      9.158281e-04  9.571416e-04  1.000208e-03  1.045093e-03
## ASV0012      1.548269e-04  1.620059e-04  1.695087e-04  1.773492e-04
## ASV9823      2.366474e-04  2.466201e-04  2.569465e-04  2.676322e-04
## ASV0008      1.656229e-04  1.732735e-04  1.812666e-04  1.896165e-04
## ASV7832     -2.010463e-03 -2.104053e-03 -2.201905e-03 -2.304207e-03
## ASV1915     -2.611053e-04 -2.728672e-04 -2.851312e-04 -2.979166e-04
## ASV0055     -1.706673e-04 -1.790425e-04 -1.878390e-04 -1.970788e-04
## ASV0032      8.718223e-05  9.093193e-05  9.482346e-05  9.886032e-05
## ASV2977     -2.843218e-03 -2.975024e-03 -3.112776e-03 -3.256726e-03
## ASV0466      2.343817e-03  2.448874e-03  2.558330e-03  2.672341e-03
## ASV3866      1.544162e-03  1.616852e-03  1.692924e-03  1.772531e-03
## ASV0040      5.617765e-04  5.879768e-04  6.153730e-04  6.440175e-04
## ASV0496     -1.093530e-04 -1.159370e-04 -1.229602e-04 -1.304547e-04
## ASV0052      4.713376e-04  4.933404e-04  5.163492e-04  5.404082e-04
## ASV3828     -1.693921e-03 -1.769701e-03 -1.848648e-03 -1.930874e-03
## ASV1930      8.572753e-04  8.963603e-04  9.371429e-04  9.796888e-04
## ASV2126      1.450611e-03  1.517366e-03  1.587083e-03  1.659885e-03
## ASV0793      1.752424e-03  1.834729e-03  1.920846e-03  2.010943e-03
## ASV0299     -3.392795e-05 -3.553821e-05 -3.722655e-05 -3.899711e-05
## ASV0208      1.272428e-03  1.331747e-03  1.393772e-03  1.458621e-03
## ASV0511     -5.417719e-04 -5.659190e-04 -5.910623e-04 -6.172354e-04
## ASV1123     -1.634252e-03 -1.707346e-03 -1.783488e-03 -1.862783e-03
## ASV0099      4.478720e-05  4.704073e-05  4.941330e-05  5.191174e-05
## ASV0752     -8.917183e-04 -9.341657e-04 -9.786299e-04 -1.025206e-03
## ASV0883      1.225535e-03  1.283724e-03  1.344664e-03  1.408485e-03
## ASV0683      1.609388e-03  1.685345e-03  1.764854e-03  1.848075e-03
## ASV4117     -2.589662e-03 -2.710253e-03 -2.836337e-03 -2.968154e-03
## ASV2172      1.790055e-04  1.866824e-04  1.946459e-04  2.029025e-04
## ASV0330     -4.818064e-04 -5.043739e-04 -5.279809e-04 -5.526734e-04
## ASV0728      2.399685e-03  2.510936e-03  2.627198e-03  2.748683e-03
## ASV0499      6.253373e-04  6.549053e-04  6.858612e-04  7.182689e-04
## ASV0120     -1.063337e-03 -1.112692e-03 -1.164277e-03 -1.218186e-03
## ASV1446      8.615219e-04  8.987195e-04  9.373406e-04  9.774226e-04
## ASV17171    -2.058969e-03 -2.154182e-03 -2.253673e-03 -2.357620e-03
## ASV0533      1.478472e-04  1.550190e-04  1.625441e-04  1.704402e-04
## ASV2495     -4.791881e-04 -5.028417e-04 -5.277019e-04 -5.538336e-04
## ASV5582      9.901075e-04  1.033605e-03  1.078837e-03  1.125859e-03
## ASV1488      3.685755e-04  3.853382e-04  4.028251e-04  4.210638e-04
## ASV0682      4.543899e-04  4.759517e-04  4.985322e-04  5.221792e-04
## ASV0068     -8.037100e-04 -8.411094e-04 -8.802071e-04 -9.210766e-04
## ASV1987     -1.963243e-03 -2.056870e-03 -2.154963e-03 -2.257732e-03
## ASV0035     -1.330530e-04 -1.401631e-04 -1.476842e-04 -1.556425e-04
## ASV7192     -1.260035e-03 -1.317718e-03 -1.377935e-03 -1.440788e-03
## ASV0873      1.547792e-04  1.436610e-04  1.303725e-04  1.146731e-04
## ASV4749      9.236319e-06  6.670836e-06  3.707204e-06  3.020069e-07
## ASV2174      8.994575e-04  9.392575e-04  9.806730e-04  1.023756e-03
## ASV1476     -8.751618e-04 -9.165756e-04 -9.599391e-04 -1.005343e-03
## ASV0740     -2.486282e-03 -2.603914e-03 -2.727072e-03 -2.856014e-03
## ASV0170     -4.927989e-04 -5.157387e-04 -5.397216e-04 -5.647926e-04
## ASV2466     -2.246919e-03 -2.351475e-03 -2.460786e-03 -2.575058e-03
## ASV1709      8.402255e-04  8.782975e-04  9.180113e-04  9.594312e-04
## ASV6170     -3.490652e-03 -3.654770e-03 -3.826503e-03 -4.006197e-03
## ASV3673      1.706158e-03  1.786862e-03  1.871357e-03  1.959817e-03
## ASV1745     -4.342308e-04 -4.552329e-04 -4.772642e-04 -5.003762e-04
##                                                                    
## (Intercept)  1.435460e-02  1.502044e-02  1.571630e-02  1.644345e-02
## ASV1236      2.872135e-03  3.002082e-03  3.137596e-03  3.278884e-03
## ASV0421      3.040053e-04  3.198799e-04  3.366354e-04  3.543245e-04
## ASV0691     -2.283118e-03 -2.382156e-03 -2.485035e-03 -2.591863e-03
## ASV0899      2.484296e-03  2.597164e-03  2.714900e-03  2.837690e-03
## ASV1004      5.743453e-03  6.003993e-03  6.275744e-03  6.559135e-03
## ASV1041     -2.365394e-03 -2.472429e-03 -2.584038e-03 -2.700390e-03
## ASV1058      3.586967e-03  3.749471e-03  3.918952e-03  4.095673e-03
## ASV12542     1.400347e-03  1.462937e-03  1.528134e-03  1.596030e-03
## ASV1294      3.336626e-03  3.487932e-03  3.645746e-03  3.810317e-03
## ASV13113     1.085349e-03  1.137223e-03  1.191583e-03  1.248548e-03
## ASV1318      3.327982e-03  3.478830e-03  3.636159e-03  3.800215e-03
## ASV2269     -5.767954e-03 -6.028939e-03 -6.301088e-03 -6.584820e-03
## ASV2542      2.763221e-03  2.892536e-03  3.027798e-03  3.169270e-03
## ASV2660     -2.299283e-03 -2.402955e-03 -2.511029e-03 -2.623667e-03
## ASV2737      8.059378e-04  8.413715e-04  8.782266e-04  9.165480e-04
## ASV2840      3.086729e-03  3.224005e-03  3.366925e-03  3.515679e-03
## ASV3053      1.574691e-02  1.645185e-02  1.718625e-02  1.795117e-02
## ASV3077      1.003192e-03  1.048201e-03  1.095102e-03  1.143963e-03
## ASV3134      1.741134e-03  1.823570e-03  1.909886e-03  2.000263e-03
## ASV3140      2.387631e-03  2.498192e-03  2.613723e-03  2.734435e-03
## ASV3579      8.249156e-04  8.650619e-04  9.071967e-04  9.514211e-04
## ASV6119     -1.578458e-03 -1.649869e-03 -1.724334e-03 -1.801967e-03
## ASV7557     -3.207378e-03 -3.352462e-03 -3.503749e-03 -3.661472e-03
## ASV8422      8.032243e-04  8.392130e-04  8.767100e-04  9.157690e-04
## ASV1086     -1.286269e-04 -1.340864e-04 -1.397468e-04 -1.456126e-04
## ASV1310      1.536005e-03  1.605575e-03  1.678127e-03  1.753774e-03
## ASV15750    -2.126478e-04 -2.219491e-04 -2.316175e-04 -2.416635e-04
## ASV16905    -6.595448e-04 -6.893790e-04 -7.204886e-04 -7.529215e-04
## ASV2033      2.765427e-03  2.895709e-03  3.032056e-03  3.174744e-03
## ASV2089      1.390338e-03  1.453270e-03  1.518896e-03  1.587317e-03
## ASV2127      4.514516e-03  4.718969e-03  4.932190e-03  5.154510e-03
## ASV2725      3.627173e-03  3.789970e-03  3.959610e-03  4.136339e-03
## ASV2804     -1.365262e-03 -1.427015e-03 -1.491407e-03 -1.558538e-03
## ASV3075      2.969479e-03  3.106135e-03  3.248868e-03  3.397930e-03
## ASV3327      4.078835e-03  4.269418e-03  4.468733e-03  4.677161e-03
## ASV3342      3.512118e-03  3.675551e-03  3.846411e-03  4.025020e-03
## ASV3532     -3.887457e-03 -4.067104e-03 -4.254801e-03 -4.450886e-03
## ASV3600      1.804657e-03  1.888287e-03  1.975686e-03  2.067015e-03
## ASV4013      3.385713e-03  3.540643e-03  3.702367e-03  3.871158e-03
## ASV4136      3.639460e-03  3.803004e-03  3.973447e-03  4.151041e-03
## ASV4195      1.393510e-02  1.456530e-02  1.522243e-02  1.590750e-02
## ASV4407     -5.383592e-03 -5.627025e-03 -5.880858e-03 -6.145479e-03
## ASV4717      9.512078e-04  9.927535e-04  1.035939e-03  1.080813e-03
## ASV6794      2.246364e-03  2.346336e-03  2.450437e-03  2.558807e-03
## ASV8324     -2.762449e-03 -2.887361e-03 -3.017610e-03 -3.153395e-03
## ASV8981     -7.744905e-05 -8.001667e-05 -8.260406e-05 -8.520312e-05
## ASV9859      9.232914e-04  9.686684e-04  1.016336e-03  1.066414e-03
## ASV0936      2.646834e-03  2.770137e-03  2.899052e-03  3.033822e-03
## ASV12683     4.920164e-08 -2.758021e-07 -6.445657e-07 -1.061400e-06
## ASV1293      1.792972e-03  1.873940e-03  1.958358e-03  2.046355e-03
## ASV13055    -4.886610e-05 -5.039147e-05 -5.191617e-05 -5.343370e-05
## ASV17063    -1.432875e-03 -1.497634e-03 -1.565157e-03 -1.635546e-03
## ASV2228      1.168431e-03  1.221231e-03  1.276283e-03  1.333672e-03
## ASV2769      1.739212e-04  1.828460e-04  1.922521e-04  2.021669e-04
## ASV2803      1.275082e-03  1.331565e-03  1.390353e-03  1.451522e-03
## ASV2896      9.964626e-04  1.043076e-03  1.091833e-03  1.142831e-03
## ASV3062      1.188151e-03  1.245348e-03  1.305322e-03  1.368208e-03
## ASV3107      1.861079e-03  1.947725e-03  2.038315e-03  2.133020e-03
## ASV3265      2.566809e-03  2.682562e-03  2.803232e-03  2.928998e-03
## ASV3666      2.585185e-05  2.691711e-05  2.801690e-05  2.915130e-05
## ASV4497      8.790304e-04  9.189739e-04  9.606430e-04  1.004104e-03
## ASV6914     -1.256810e-04 -1.320214e-04 -1.386959e-04 -1.457231e-04
## ASV0576     -3.092528e-03 -3.228823e-03 -3.370614e-03 -3.518074e-03
## ASV0673      3.378878e-03  3.533154e-03  3.694162e-03  3.862169e-03
## ASV0772      1.565368e-03  1.637162e-03  1.712123e-03  1.790378e-03
## ASV0862      1.267500e-04  1.352332e-04  1.443400e-04  1.541189e-04
## ASV0898      1.200211e-03  1.257017e-03  1.316491e-03  1.378756e-03
## ASV0910      1.392939e-03  1.458020e-03  1.526084e-03  1.597262e-03
## ASV0964     -1.165425e-03 -1.217213e-03 -1.271128e-03 -1.327241e-03
## ASV10059     9.828548e-04  1.029704e-03  1.078787e-03  1.130208e-03
## ASV10263    -2.182383e-03 -2.281094e-03 -2.384024e-03 -2.491332e-03
## ASV1088      2.489945e-03  2.605563e-03  2.726420e-03  2.852740e-03
## ASV1101      3.122279e-03  3.263248e-03  3.410219e-03  3.563414e-03
## ASV1183      8.178540e-04  8.556423e-04  8.951228e-04  9.363666e-04
## ASV11956     8.078651e-04  8.433760e-04  8.803100e-04  9.187115e-04
## ASV12774     5.344261e-05  5.505625e-05  5.666183e-05  5.825157e-05
## ASV1321      3.589044e-03  3.757553e-03  3.933859e-03  4.118314e-03
## ASV13793    -1.504712e-03 -1.572766e-03 -1.643730e-03 -1.717711e-03
## ASV14482     9.863657e-05  1.027814e-04  1.070758e-04  1.115231e-04
## ASV15483     6.112085e-04  6.397261e-04  6.695462e-04  7.007255e-04
## ASV2062      2.873166e-03  3.004429e-03  3.141431e-03  3.284401e-03
## ASV2132      2.327578e-03  2.435970e-03  2.549295e-03  2.667765e-03
## ASV2413      2.229038e-03  2.330027e-03  2.435354e-03  2.545182e-03
## ASV2490      6.900400e-03  7.208758e-03  7.529955e-03  7.864440e-03
## ASV2594      8.507020e-04  8.900283e-04  9.311211e-04  9.740556e-04
## ASV2822     -3.970942e-03 -4.150592e-03 -4.337928e-03 -4.533235e-03
## ASV2863      4.235843e-03  4.426236e-03  4.624666e-03  4.831424e-03
## ASV2910      1.546968e-03  1.616848e-03  1.689709e-03  1.765660e-03
## ASV2980      1.716897e-03  1.795487e-03  1.877528e-03  1.963156e-03
## ASV3307      3.159353e-03  3.302247e-03  3.451249e-03  3.606589e-03
## ASV3474      2.049779e-03  2.146617e-03  2.247992e-03  2.354110e-03
## ASV3502      2.175046e-03  2.275336e-03  2.380096e-03  2.489514e-03
## ASV4236      3.248911e-03  3.393610e-03  3.544282e-03  3.701130e-03
## ASV4842     -3.405474e-04 -3.566833e-04 -3.735725e-04 -3.912486e-04
## ASV4894     -1.505003e-03 -1.573087e-03 -1.644082e-03 -1.718099e-03
## ASV5290      1.182190e-03  1.237130e-03  1.294558e-03  1.354582e-03
## ASV5501      7.253411e-04  7.587521e-04  7.936530e-04  8.301061e-04
## ASV5795      7.937706e-04  8.307267e-04  8.693633e-04  9.097531e-04
## ASV5987     -4.203761e-03 -4.393955e-03 -4.592287e-03 -4.799060e-03
## ASV6267     -4.736463e-03 -4.950729e-03 -5.174159e-03 -5.407097e-03
## ASV6862      1.910631e-03  1.996050e-03  2.085030e-03  2.177697e-03
## ASV7145      8.474734e-04  8.849251e-04  9.239018e-04  9.644542e-04
## ASV7673     -1.504928e-03 -1.573006e-03 -1.643994e-03 -1.718003e-03
## ASV7789      7.212318e-04  7.564879e-04  7.935050e-04  8.323739e-04
## ASV7809      4.123839e-05  4.412033e-05  4.722179e-05  5.056024e-05
## ASV8002     -1.900642e-03 -1.986617e-03 -2.076270e-03 -2.169737e-03
## ASV8205      7.877470e-04  8.242531e-04  8.624045e-04  9.022714e-04
## ASV9155     -4.859010e-04 -5.075997e-04 -5.301994e-04 -5.537313e-04
## ASV9221      1.783294e-04  1.881728e-04  1.986075e-04  2.096724e-04
## ASV9311     -3.048882e-03 -3.186788e-03 -3.330591e-03 -3.480512e-03
## ASV9557     -2.083535e-03 -2.177764e-03 -2.276021e-03 -2.378457e-03
## ASV9936     -4.201438e-03 -4.391423e-03 -4.589528e-03 -4.796055e-03
## ASV1445      2.524924e-03  2.642025e-03  2.764409e-03  2.892302e-03
## ASV4232      9.437446e-04  9.887056e-04  1.035811e-03  1.085162e-03
## ASV6479      3.196926e-04  3.366827e-04  3.546409e-04  3.736268e-04
## ASV0142     -1.814730e-03 -1.896434e-03 -1.981597e-03 -2.070347e-03
## ASV0378      8.036906e-04  8.420157e-04  8.821687e-04  9.242365e-04
## ASV1122      2.439269e-03  2.552868e-03  2.671636e-03  2.795799e-03
## ASV0123     -1.603368e-03 -1.675472e-03 -1.750621e-03 -1.828925e-03
## ASV2064      8.297069e-04  8.660837e-04  9.039057e-04  9.432162e-04
## ASV4459     -1.189832e-04 -1.239069e-04 -1.289993e-04 -1.342629e-04
## ASV0448      6.423871e-04  6.730509e-04  7.051796e-04  7.388429e-04
## ASV0397      1.442817e-03  1.509116e-03  1.578348e-03  1.650635e-03
## ASV0485      1.682981e-03  1.759686e-03  1.839729e-03  1.923240e-03
## ASV1566      2.472036e-03  2.585448e-03  2.703863e-03  2.827480e-03
## ASV1365      2.104032e-03  2.201282e-03  2.302888e-03  2.409029e-03
## ASV1065      2.992364e-03  3.130439e-03  3.274678e-03  3.425338e-03
## ASV0722     -1.545455e-04 -1.618384e-04 -1.694730e-04 -1.774654e-04
## ASV12660    -1.739911e-03 -1.817917e-03 -1.899197e-03 -1.983871e-03
## ASV0223      4.644082e-04  4.856228e-04  5.077657e-04  5.308739e-04
## ASV0229      7.020704e-04  7.348032e-04  7.690300e-04  8.048162e-04
## ASV0877      3.037805e-04  3.170406e-04  3.308179e-04  3.451266e-04
## ASV0983      1.673059e-03  1.749068e-03  1.828359e-03  1.911059e-03
## ASV0626      1.621028e-04  1.713033e-04  1.810734e-04  1.914511e-04
## ASV4146      8.240931e-05  8.616247e-05  9.007437e-05  9.415018e-05
## ASV4175     -2.040251e-03 -2.135111e-03 -2.234273e-03 -2.337921e-03
## ASV2082     -8.846835e-04 -9.291376e-04 -9.759220e-04 -1.025166e-03
## ASV2272      9.730925e-04  1.018168e-03  1.065273e-03  1.114497e-03
## ASV2245     -1.454717e-03 -1.522594e-03 -1.593572e-03 -1.667784e-03
## ASV0590     -8.243213e-04 -8.667829e-04 -9.115565e-04 -9.587770e-04
## ASV0217      5.135499e-05  5.619120e-05  6.147260e-05  6.723876e-05
## ASV0416      1.140581e-03  1.190232e-03  1.241822e-03  1.295407e-03
## ASV1056      1.400614e-03  1.466576e-03  1.535606e-03  1.607845e-03
## ASV7777     -1.989210e-03 -2.081340e-03 -2.177617e-03 -2.278218e-03
## ASV0455      3.578133e-04  3.743084e-04  3.915382e-04  4.095331e-04
## ASV0604      9.185898e-04  9.621990e-04  1.007869e-03  1.055695e-03
## ASV6100     -1.365557e-03 -1.429308e-03 -1.495977e-03 -1.565691e-03
## ASV11359    -2.946044e-03 -3.082559e-03 -3.225222e-03 -3.374293e-03
## ASV6604      4.045735e-04  4.237181e-04  4.437617e-04  4.647459e-04
## ASV5004     -1.050346e-03 -1.098765e-03 -1.149342e-03 -1.202168e-03
## ASV1483     -4.533136e-04 -4.741260e-04 -4.958577e-04 -5.185461e-04
## ASV9773     -1.325024e-03 -1.386619e-03 -1.451008e-03 -1.518312e-03
## ASV4059     -1.570434e-05 -1.457183e-05 -1.321523e-05 -1.160917e-05
## ASV1193      1.608956e-03  1.682956e-03  1.760238e-03  1.840934e-03
## ASV4610     -2.791988e-04 -2.894176e-04 -2.998517e-04 -3.104889e-04
## ASV0742     -1.738590e-04 -1.797139e-04 -1.856300e-04 -1.915914e-04
## ASV1502     -5.912354e-05 -6.319551e-05 -6.757462e-05 -7.228522e-05
## ASV0195      4.708120e-05  4.841389e-05  4.972934e-05  5.101996e-05
## ASV1213      1.154278e-03  1.205278e-03  1.258346e-03  1.313549e-03
## ASV1648     -1.227176e-03 -1.284389e-03 -1.344215e-03 -1.406767e-03
## ASV6984     -1.147836e-03 -1.201381e-03 -1.257376e-03 -1.315926e-03
## ASV0396     -7.447242e-05 -7.696831e-05 -7.949005e-05 -8.203114e-05
## ASV4297      1.665645e-03  1.740109e-03  1.817673e-03  1.898448e-03
## ASV2622      2.568695e-03  2.685027e-03  2.806349e-03  2.932850e-03
## ASV3512      9.656325e-04  1.012852e-03  1.062433e-03  1.114498e-03
## ASV2411      1.718286e-03  1.799352e-03  1.884205e-03  1.973019e-03
## ASV2291     -7.080794e-04 -7.450325e-04 -7.840356e-04 -8.252110e-04
## ASV0807      2.369306e-03  2.478324e-03  2.592179e-03  2.711070e-03
## ASV1292      5.863306e-04  6.118437e-04  6.383540e-04  6.658900e-04
## ASV1035      2.194144e-03  2.292871e-03  2.395778e-03  2.503018e-03
## ASV0070      1.022836e-05  1.158002e-05  1.307516e-05  1.472757e-05
## ASV0255      2.105904e-04  2.197994e-04  2.293708e-04  2.393152e-04
## ASV0057     -6.082789e-04 -6.351892e-04 -6.631930e-04 -6.923255e-04
## ASV0077     -1.322519e-04 -1.377729e-04 -1.434861e-04 -1.493943e-04
## ASV0625      1.266153e-03  1.322857e-03  1.381933e-03  1.443465e-03
## ASV2464      8.627777e-03  9.012738e-03  9.413699e-03  9.831222e-03
## ASV1315      2.235424e-03  2.341240e-03  2.452031e-03  2.568027e-03
## ASV2673      1.916650e-03  2.007465e-03  2.102558e-03  2.202128e-03
## ASV2161      8.113849e-04  8.497351e-04  8.898844e-04  9.319158e-04
## ASV0337     -4.675686e-04 -4.893478e-04 -5.121184e-04 -5.359231e-04
## ASV7680     -3.048899e-03 -3.191188e-03 -3.339981e-03 -3.495563e-03
## ASV0611      1.702119e-03  1.781628e-03  1.864779e-03  1.951733e-03
## ASV3118     -1.753962e-03 -1.837362e-03 -1.924717e-03 -2.016213e-03
## ASV1284      6.885748e-04  7.144679e-04  7.409662e-04  7.680436e-04
## ASV0889      1.302124e-03  1.361324e-03  1.423088e-03  1.487515e-03
## ASV4649     -6.479430e-04 -6.778948e-04 -7.091895e-04 -7.418835e-04
## ASV1108     -1.307215e-03 -1.369924e-03 -1.435659e-03 -1.504567e-03
## ASV0738      7.103210e-04  7.457294e-04  7.829673e-04  8.221338e-04
## ASV0473     -1.392982e-04 -1.468223e-04 -1.547817e-04 -1.632031e-04
## ASV0598     -3.586412e-04 -3.770013e-04 -3.963532e-04 -4.167546e-04
## ASV0429      9.703346e-04  1.014028e-03  1.059570e-03  1.107027e-03
## ASV1549      1.767718e-03  1.851559e-03  1.939358e-03  2.031298e-03
## ASV1203      1.414393e-03  1.478900e-03  1.546215e-03  1.616449e-03
## ASV4532      6.444749e-05  6.697139e-05  6.956805e-05  7.223712e-05
## ASV0274      2.396468e-04  2.513564e-04  2.636484e-04  2.765525e-04
## ASV0163     -1.101286e-03 -1.150466e-03 -1.201691e-03 -1.255033e-03
## ASV1298      1.239083e-04  1.290391e-04  1.343478e-04  1.398374e-04
## ASV9424     -2.360550e-03 -2.471054e-03 -2.586643e-03 -2.707544e-03
## ASV0412      2.458037e-03  2.569640e-03  2.686059e-03  2.807479e-03
## ASV0284      5.254682e-04  5.479765e-04  5.713282e-04  5.955437e-04
## ASV0620     -4.856859e-04 -5.099236e-04 -5.354146e-04 -5.622268e-04
## ASV0153     -2.363512e-03 -2.475601e-03 -2.592978e-03 -2.715890e-03
## ASV0498      8.387966e-04  8.779981e-04  9.189940e-04  9.618628e-04
## ASV0097      4.643897e-04  4.864012e-04  5.094506e-04  5.335865e-04
## ASV0104     -3.324511e-03 -3.477009e-03 -3.636227e-03 -3.802439e-03
## ASV1282      1.155821e-03  1.207725e-03  1.261810e-03  1.318153e-03
## ASV3883     -8.918689e-04 -9.352286e-04 -9.807292e-04 -1.028479e-03
## ASV0801      4.475658e-04  4.684574e-04  4.903034e-04  5.131455e-04
## ASV1611     -2.111076e-03 -2.210534e-03 -2.314626e-03 -2.423563e-03
## ASV0227     -3.688638e-04 -3.877578e-04 -4.076692e-04 -4.286566e-04
## ASV0833      7.212076e-04  7.547779e-04  7.898731e-04  8.265590e-04
## ASV0718      3.230417e-03  3.380276e-03  3.536904e-03  3.700590e-03
## ASV1139      4.358145e-04  4.536793e-04  4.721304e-04  4.911725e-04
## ASV0766     -4.430602e-04 -4.646572e-04 -4.873246e-04 -5.111166e-04
## ASV2091      2.658197e-03  2.777344e-03  2.901483e-03  3.030791e-03
## ASV1238     -2.392975e-03 -2.505108e-03 -2.622416e-03 -2.745130e-03
## ASV9193     -2.143394e-04 -2.262669e-04 -2.389204e-04 -2.523482e-04
## ASV0290      3.542163e-04  3.691824e-04  3.846904e-04  4.007518e-04
## ASV0231      9.676192e-04  1.011553e-03  1.057382e-03  1.105178e-03
## ASV0185      5.456704e-04  5.727889e-04  6.013015e-04  6.312833e-04
## ASV2330      1.118289e-03  1.167911e-03  1.219565e-03  1.273317e-03
## ASV3119     -4.949728e-04 -5.194645e-04 -5.452051e-04 -5.722612e-04
## ASV2368     -1.222210e-03 -1.280237e-03 -1.341012e-03 -1.404665e-03
## ASV0122     -6.000410e-04 -6.274539e-04 -6.560653e-04 -6.859228e-04
## ASV1044      1.520869e-03  1.592539e-03  1.667551e-03  1.746056e-03
## ASV0160     -6.506799e-04 -6.795903e-04 -7.096882e-04 -7.410135e-04
## ASV0326      1.689917e-04  1.768747e-04  1.851169e-04  1.937336e-04
## ASV1388      3.109786e-03  3.252244e-03  3.400963e-03  3.556194e-03
## ASV0792      2.319849e-03  2.424575e-03  2.533760e-03  2.647570e-03
## ASV0036     -7.088344e-04 -7.424741e-04 -7.777023e-04 -8.145930e-04
## ASV2125      2.219754e-03  2.321850e-03  2.428472e-03  2.539806e-03
## ASV1075     -3.343904e-05 -3.496934e-05 -3.656786e-05 -3.823759e-05
## ASV0390      1.170891e-03  1.226406e-03  1.284542e-03  1.345421e-03
## ASV3790     -1.673241e-03 -1.751267e-03 -1.832854e-03 -1.918158e-03
## ASV1535     -4.727215e-04 -4.959856e-04 -5.204251e-04 -5.461016e-04
## ASV0263      2.055782e-03  2.150844e-03  2.250169e-03  2.353937e-03
## ASV0675      3.072734e-03  3.216847e-03  3.367615e-03  3.525335e-03
## ASV3348      2.459212e-04  2.578442e-04  2.703533e-04  2.834775e-04
## ASV0058     -9.204428e-04 -9.625246e-04 -1.006448e-03 -1.052287e-03
## ASV4142      1.297995e-03  1.356516e-03  1.417517e-03  1.481089e-03
## ASV0059     -7.426683e-04 -7.764750e-04 -8.117474e-04 -8.485423e-04
## ASV0013     -1.313036e-03 -1.373681e-03 -1.437040e-03 -1.503224e-03
## ASV0033     -6.167078e-04 -6.459071e-04 -6.764791e-04 -7.084874e-04
## ASV4354     -7.732749e-04 -8.090007e-04 -8.463293e-04 -8.853287e-04
## ASV0022     -5.209285e-04 -5.455745e-04 -5.713779e-04 -5.983919e-04
## ASV0134     -4.914075e-04 -5.151549e-04 -5.400632e-04 -5.661902e-04
## ASV0415      7.620992e-05  8.023946e-05  8.449497e-05  8.898982e-05
## ASV10103    -2.902991e-03 -3.039188e-03 -3.181677e-03 -3.330740e-03
## ASV1613      2.198662e-03  2.298004e-03  2.401583e-03  2.509555e-03
## ASV0135     -2.849883e-04 -2.975856e-04 -3.106933e-04 -3.243279e-04
## ASV0469     -2.828905e-03 -2.957761e-03 -3.092217e-03 -3.232492e-03
## ASV0471      1.713601e-03  1.792611e-03  1.875143e-03  1.961342e-03
## ASV0451     -2.662465e-04 -2.801635e-04 -2.948544e-04 -3.103653e-04
## ASV0747      9.719342e-04  1.017125e-03  1.064365e-03  1.113742e-03
## ASV1314     -9.672557e-04 -1.013248e-03 -1.061423e-03 -1.111885e-03
## ASV0425     -3.519540e-03 -3.677859e-03 -3.842867e-03 -4.014805e-03
## ASV0559     -8.634527e-04 -9.030922e-04 -9.444871e-04 -9.877098e-04
## ASV0148     -2.047369e-04 -2.130927e-04 -2.217185e-04 -2.306155e-04
## ASV0129      1.830656e-04  1.935972e-04  2.047963e-04  2.167095e-04
## ASV1072      2.374195e-04  2.476678e-04  2.583066e-04  2.693455e-04
## ASV2390      1.811743e-03  1.892306e-03  1.976178e-03  2.063472e-03
## ASV0548      1.180051e-03  1.234357e-03  1.291074e-03  1.350300e-03
## ASV0168     -6.085954e-04 -6.362849e-04 -6.651742e-04 -6.953098e-04
## ASV0066     -6.841715e-04 -7.154692e-04 -7.481379e-04 -7.822320e-04
## ASV0468     -3.605111e-04 -3.772102e-04 -3.946614e-04 -4.128967e-04
## ASV0172     -2.102074e-04 -2.192395e-04 -2.286119e-04 -2.383328e-04
## ASV0236     -6.190475e-05 -6.207895e-05 -6.200914e-05 -6.166170e-05
## ASV0250      9.402565e-04  9.860456e-04  1.034107e-03  1.084557e-03
## ASV0338      4.508656e-04  4.722809e-04  4.947066e-04  5.181892e-04
## ASV0450     -8.003634e-05 -8.433259e-05 -8.887701e-05 -9.368514e-05
## ASV0377      8.554172e-04  8.944657e-04  9.352179e-04  9.777411e-04
## ASV1022     -3.714233e-05 -3.875676e-05 -4.043250e-05 -4.217088e-05
## ASV6174     -1.619628e-05 -1.721493e-05 -1.830641e-05 -1.947653e-05
## ASV0786     -1.086040e-04 -1.147699e-04 -1.213167e-04 -1.282697e-04
## ASV0053     -9.198777e-04 -9.624983e-04 -1.007038e-03 -1.053577e-03
## ASV0697     -5.653542e-04 -5.908739e-04 -6.174812e-04 -6.452165e-04
## ASV0785      1.184704e-03  1.238811e-03  1.295281e-03  1.354208e-03
## ASV1967     -1.179816e-03 -1.233380e-03 -1.289259e-03 -1.347541e-03
## ASV0385      3.889252e-04  4.075189e-04  4.270020e-04  4.474167e-04
## ASV0295      6.254959e-05  6.626518e-05  7.022506e-05  7.444681e-05
## ASV0072     -9.237262e-04 -9.655595e-04 -1.009185e-03 -1.054671e-03
## ASV0157     -1.277479e-04 -1.324133e-04 -1.371704e-04 -1.420119e-04
## ASV0501      1.984472e-03  2.076617e-03  2.172929e-03  2.273587e-03
## ASV10729    -2.489752e-03 -2.605853e-03 -2.727252e-03 -2.854180e-03
## ASV1470      1.295852e-03  1.353231e-03  1.412946e-03  1.475073e-03
## ASV0050     -2.165389e-03 -2.264470e-03 -2.367896e-03 -2.475838e-03
## ASV0411     -4.825363e-04 -5.053188e-04 -5.291671e-04 -5.541299e-04
## ASV0549      7.779374e-04  8.144037e-04  8.525515e-04  8.924557e-04
## ASV0184      2.626008e-04  2.746132e-04  2.871535e-04  3.002429e-04
## ASV0705      5.215760e-04  5.451950e-04  5.698259e-04  5.955065e-04
## ASV1715      1.093679e-03  1.144298e-03  1.197191e-03  1.252454e-03
## ASV0603      1.691494e-04  1.771201e-04  1.854640e-04  1.941983e-04
## ASV0826      1.852511e-03  1.937565e-03  2.026376e-03  2.119097e-03
## ASV0034     -5.962495e-04 -6.232988e-04 -6.515118e-04 -6.809330e-04
## ASV0838      4.335849e-04  4.507466e-04  4.684027e-04  4.865476e-04
## ASV0614     -5.074752e-04 -5.307430e-04 -5.550365e-04 -5.803970e-04
## ASV0014     -1.342886e-03 -1.404690e-03 -1.469238e-03 -1.536643e-03
## ASV0585      1.684096e-04  1.739525e-04  1.795346e-04  1.851381e-04
## ASV0016     -1.402849e-03 -1.467411e-03 -1.534840e-03 -1.605252e-03
## ASV5394     -1.047832e-03 -1.096496e-03 -1.147362e-03 -1.200524e-03
## ASV0666      2.313552e-03  2.417881e-03  2.526643e-03  2.640001e-03
## ASV2085      5.613863e-04  5.835360e-04  6.063252e-04  6.297485e-04
## ASV0003     -9.568439e-04 -1.000851e-03 -1.046810e-03 -1.094799e-03
## ASV0346      4.741897e-04  4.967637e-04  5.204092e-04  5.451765e-04
## ASV0267     -1.059339e-05 -1.035201e-05 -1.003071e-05 -9.619673e-06
## ASV0353      7.572388e-04  7.928966e-04  8.302139e-04  8.692660e-04
## ASV2419      2.064561e-03  2.158983e-03  2.257542e-03  2.360403e-03
## ASV0447      1.109100e-03  1.161455e-03  1.216258e-03  1.273619e-03
## ASV0654      1.660155e-03  1.736660e-03  1.816570e-03  1.900027e-03
## ASV0151      2.135466e-04  2.242580e-04  2.355293e-04  2.473914e-04
## ASV0065     -6.443480e-04 -6.738357e-04 -7.046169e-04 -7.367434e-04
## ASV0527      1.581939e-03  1.654597e-03  1.730468e-03  1.809683e-03
## ASV4055     -2.441545e-04 -2.560155e-04 -2.684642e-04 -2.815308e-04
## ASV0166     -8.008690e-04 -8.369838e-04 -8.746329e-04 -9.138726e-04
## ASV0417     -3.316611e-04 -3.461870e-04 -3.612888e-04 -3.769837e-04
## ASV0078     -4.735013e-04 -4.949708e-04 -5.173626e-04 -5.407116e-04
## ASV0322     -9.230446e-05 -9.589187e-05 -9.957224e-05 -1.033425e-04
## ASV0156     -1.113220e-03 -1.165119e-03 -1.219388e-03 -1.276128e-03
## ASV0648     -2.413559e-03 -2.526498e-03 -2.644627e-03 -2.768176e-03
## ASV0407     -1.795443e-04 -1.880989e-04 -1.970613e-04 -2.064508e-04
## ASV2030     -4.074045e-04 -4.258646e-04 -4.451250e-04 -4.652177e-04
## ASV0300      2.860143e-04  2.996251e-04  3.138822e-04  3.288160e-04
## ASV1150      6.237910e-05  6.555742e-05  6.890533e-05  7.243238e-05
## ASV0958      8.831735e-04  9.252564e-04  9.693446e-04  1.015534e-03
## ASV0216     -9.965344e-04 -1.041917e-03 -1.089274e-03 -1.138683e-03
## ASV0446      1.487161e-03  1.556779e-03  1.629596e-03  1.705756e-03
## ASV0367     -9.778624e-04 -1.023256e-03 -1.070702e-03 -1.120289e-03
## ASV0200     -5.819438e-04 -6.089316e-04 -6.371370e-04 -6.666116e-04
## ASV0334     -3.283776e-04 -3.422161e-04 -3.565520e-04 -3.713951e-04
## ASV1311      3.928323e-04  4.098947e-04  4.276192e-04  4.460239e-04
## ASV0458      5.829026e-04  6.079639e-04  6.339756e-04  6.609620e-04
## ASV1371      8.939484e-05  9.379673e-05  9.842015e-05  1.032765e-04
## ASV0418      1.314011e-03  1.373041e-03  1.434559e-03  1.498654e-03
## ASV0004      1.908115e-04  1.993495e-04  2.082439e-04  2.175073e-04
## ASV1943      3.730929e-03  3.889521e-03  4.053983e-03  4.224456e-03
## ASV1495     -2.413567e-04 -2.545741e-04 -2.685778e-04 -2.834188e-04
## ASV0901     -1.092509e-03 -1.143864e-03 -1.197603e-03 -1.253832e-03
## ASV0628      5.960594e-04  6.223815e-04  6.497675e-04  6.782512e-04
## ASV0400      3.590848e-04  3.753214e-04  3.922508e-04  4.098988e-04
## ASV0116     -3.214936e-04 -3.365822e-04 -3.523687e-04 -3.688845e-04
## ASV0788      2.839567e-03  2.973079e-03  3.112789e-03  3.258977e-03
## ASV0117      2.073420e-04  2.173024e-04  2.277444e-04  2.386915e-04
## ASV3137     -6.754449e-05 -7.060033e-05 -7.378692e-05 -7.710917e-05
## ASV0001      2.052085e-04  2.143551e-04  2.238802e-04  2.337965e-04
## ASV1651      5.830827e-04  6.092477e-04  6.365123e-04  6.649158e-04
## ASV1692      2.366140e-03  2.477254e-03  2.593513e-03  2.715147e-03
## ASV0660      8.688787e-04  9.069640e-04  9.465597e-04  9.877107e-04
## ASV0508      4.394209e-05  4.582801e-05  4.778523e-05  4.981558e-05
## ASV1660     -4.684930e-04 -4.914328e-04 -5.155186e-04 -5.408092e-04
## ASV0233      7.348983e-04  7.689496e-04  8.045350e-04  8.417193e-04
## ASV1343     -1.348796e-03 -1.411993e-03 -1.478102e-03 -1.547255e-03
## ASV0209      6.858836e-04  7.165013e-04  7.483899e-04  7.815934e-04
## ASV0193     -7.990652e-04 -8.349228e-04 -8.722863e-04 -9.112097e-04
## ASV0357      2.927810e-04  3.074391e-04  3.228615e-04  3.390909e-04
## ASV0198      6.027541e-04  6.302433e-04  6.589300e-04  6.888613e-04
## ASV0007      1.819501e-04  1.899741e-04  1.983218e-04  2.070034e-04
## ASV1772     -2.723227e-04 -2.841661e-04 -2.964667e-04 -3.092363e-04
## ASV0009      1.510364e-04  1.576202e-04  1.644622e-04  1.715696e-04
## ASV0006     -1.590210e-04 -1.666299e-04 -1.746041e-04 -1.829612e-04
## ASV0011     -5.569907e-04 -5.830085e-04 -6.102177e-04 -6.386707e-04
## ASV0015      1.141728e-04  1.191481e-04  1.243181e-04  1.296884e-04
## ASV0017      1.285820e-04  1.341892e-04  1.400166e-04  1.460703e-04
## ASV0235     -5.137226e-04 -5.378257e-04 -5.630419e-04 -5.894208e-04
## ASV0382      4.020712e-04  4.209504e-04  4.407006e-04  4.613601e-04
## ASV2357      1.678676e-03  1.757003e-03  1.838911e-03  1.924556e-03
## ASV0567     -3.243945e-04 -3.396134e-04 -3.555372e-04 -3.721978e-04
## ASV0165      2.800707e-04  2.931412e-04  3.068087e-04  3.210994e-04
## ASV0005      4.087447e-04  4.275475e-04  4.471839e-04  4.676880e-04
## ASV0384     -5.002432e-05 -5.170185e-05 -5.339445e-05 -5.509708e-05
## ASV0002      7.716036e-05  8.063210e-05  8.425085e-05  8.802205e-05
## ASV3017      2.185643e-03  2.283842e-03  2.386178e-03  2.492798e-03
## ASV0091     -5.517199e-05 -5.767397e-05 -6.028419e-05 -6.300695e-05
## ASV0186     -8.225741e-04 -8.605617e-04 -9.002474e-04 -9.417018e-04
## ASV0370      4.385145e-04  4.585141e-04  4.793839e-04  5.011579e-04
## ASV0018      5.231753e-04  5.472932e-04  5.724853e-04  5.987959e-04
## ASV1377      5.288253e-03  5.527202e-03  5.776347e-03  6.036069e-03
## ASV0019      5.487159e-04  5.740269e-04  6.004669e-04  6.280825e-04
## ASV0023     -3.404314e-04 -3.564278e-04 -3.731652e-04 -3.906771e-04
## ASV2194      5.455209e-04  5.713420e-04  5.983784e-04  6.266867e-04
## ASV1155      2.214893e-03  2.314647e-03  2.418641e-03  2.527036e-03
## ASV0510     -6.009473e-04 -6.272208e-04 -6.545295e-04 -6.829036e-04
## ASV2371     -1.333408e-03 -1.393514e-03 -1.456177e-03 -1.521494e-03
## ASV0024     -4.242841e-04 -4.441777e-04 -4.649890e-04 -4.867590e-04
## ASV2452      1.350354e-03  1.410053e-03  1.472172e-03  1.536789e-03
## ASV2332     -3.819618e-03 -3.992863e-03 -4.173579e-03 -4.362056e-03
## ASV2591      9.620410e-04  1.009988e-03  1.060392e-03  1.113382e-03
## ASV0521      8.623833e-04  9.027754e-04  9.450277e-04  9.892228e-04
## ASV5542      8.250147e-04  8.637387e-04  9.042476e-04  9.466201e-04
## ASV0336     -9.749057e-05 -1.027956e-04 -1.084121e-04 -1.143596e-04
## ASV10102     1.525551e-03  1.596985e-03  1.671703e-03  1.749851e-03
## ASV16823    -2.407717e-03 -2.514509e-03 -2.625684e-03 -2.741391e-03
## ASV3104      1.245643e-02  1.300885e-02  1.358393e-02  1.418245e-02
## ASV0781      1.713420e-03  1.792294e-03  1.874672e-03  1.960697e-03
## ASV10899     9.722549e-04  1.020770e-03  1.071789e-03  1.125448e-03
## ASV11222    -4.237051e-03 -4.424943e-03 -4.620543e-03 -4.824113e-03
## ASV11327    -3.803629e-03 -3.972279e-03 -4.147845e-03 -4.330562e-03
## ASV12458    -4.235951e-03 -4.423743e-03 -4.619236e-03 -4.822688e-03
## ASV1636      2.371612e-03  2.479217e-03  2.591453e-03  2.708497e-03
## ASV1890     -1.967807e-03 -2.052867e-03 -2.141212e-03 -2.232936e-03
## ASV2898      3.179191e-03  3.323503e-03  3.474036e-03  3.631028e-03
## ASV8328      3.179328e-04  3.385571e-04  3.606504e-04  3.843234e-04
## ASV0709     -3.530199e-03 -3.692012e-03 -3.860940e-03 -4.037269e-03
## ASV0856      2.890290e-03  3.027222e-03  3.170599e-03  3.320716e-03
## ASV0909      7.999937e-04  8.415500e-04  8.853960e-04  9.316672e-04
## ASV0937     -2.058277e-03 -2.154398e-03 -2.254926e-03 -2.360058e-03
## ASV11390    -6.044963e-03 -6.312926e-03 -6.591872e-03 -6.882175e-03
## ASV11966     1.405809e-03  1.473461e-03  1.544387e-03  1.618747e-03
## ASV12990     1.047243e-03  1.094579e-03  1.143930e-03  1.195370e-03
## ASV14797     1.556547e-03  1.626321e-03  1.699020e-03  1.774747e-03
## ASV14904    -8.674087e-03 -9.058582e-03 -9.458838e-03 -9.875387e-03
## ASV15304     8.700199e-04  9.130417e-04  9.582456e-04  1.005746e-03
## ASV16696    -2.996769e-03 -3.129594e-03 -3.267862e-03 -3.411758e-03
## ASV1690      4.906136e-03  5.139217e-03  5.383305e-03  5.638910e-03
## ASV2029      3.475145e-03  3.633898e-03  3.799593e-03  3.972504e-03
## ASV2834      4.318707e-03  4.519767e-03  4.729969e-03  4.949709e-03
## ASV4003      3.496143e-03  3.664352e-03  3.840720e-03  4.025646e-03
## ASV4064      2.044563e-03  2.140258e-03  2.240348e-03  2.345027e-03
## ASV4294      1.205090e-03  1.264559e-03  1.327041e-03  1.392694e-03
## ASV4609      1.176645e-03  1.230293e-03  1.286273e-03  1.344673e-03
## ASV6283     -2.801497e-03 -2.925678e-03 -3.054949e-03 -3.189482e-03
## ASV6491     -4.014896e-03 -4.192838e-03 -4.378072e-03 -4.570845e-03
## ASV7453      1.860893e-03  1.950802e-03  2.045095e-03  2.143986e-03
## ASV7959      6.467521e-04  6.802490e-04  7.155764e-04  7.528406e-04
## ASV8219      3.469500e-02  3.623261e-02  3.783322e-02  3.949897e-02
## ASV8547     -3.593847e-03 -3.753097e-03 -3.918870e-03 -4.091388e-03
## ASV9319      1.517603e-03  1.589331e-03  1.664419e-03  1.743021e-03
## ASV9382     -7.031309e-03 -7.342855e-03 -7.667162e-03 -8.004661e-03
## ASV11516    -4.695742e-03 -4.903775e-03 -5.120326e-03 -5.345683e-03
## ASV14377    -3.390140e-03 -3.540311e-03 -3.696630e-03 -3.859303e-03
## ASV1867      2.558458e-03  2.678143e-03  2.803324e-03  2.934242e-03
## ASV1895      1.320001e-03  1.378448e-03  1.439267e-03  1.502533e-03
## ASV3168      1.650956e-03  1.725039e-03  1.802227e-03  1.882628e-03
## ASV4449      8.988999e-03  9.401929e-03  9.833156e-03  1.028343e-02
## ASV6596      1.820662e-03  1.909103e-03  2.001909e-03  2.099300e-03
## ASV7492     -3.870592e-04 -4.003335e-04 -4.137844e-04 -4.273823e-04
## ASV9854     -7.288928e-04 -7.607877e-04 -7.939561e-04 -8.284384e-04
## ASV6296      5.687940e-02  5.939855e-02  6.202078e-02  6.474957e-02
## ASV4201      2.205078e-04  2.353922e-04  2.513745e-04  2.685396e-04
## ASV0552      1.772841e-03  1.855537e-03  1.942007e-03  2.032418e-03
## ASV3671     -1.195000e-03 -1.249385e-03 -1.306140e-03 -1.365361e-03
## ASV3529     -3.476708e-04 -3.599495e-04 -3.724409e-04 -3.851251e-04
## ASV1060      4.672447e-04  4.894485e-04  5.127058e-04  5.370666e-04
## ASV0239     -6.554325e-04 -6.842900e-04 -7.143081e-04 -7.455234e-04
## ASV5711     -2.926739e-03 -3.059465e-03 -3.197915e-03 -3.342312e-03
## ASV4152     -4.101666e-03 -4.291311e-03 -4.489469e-03 -4.696499e-03
## ASV1461      2.109961e-03  2.203359e-03  2.300557e-03  2.401681e-03
## ASV2877      1.091860e-03  1.140577e-03  1.191312e-03  1.244134e-03
## ASV0012      1.855416e-04  1.941008e-04  2.030422e-04  2.123817e-04
## ASV9823      2.786825e-04  2.901015e-04  3.018925e-04  3.140578e-04
## ASV0008      1.983381e-04  2.074468e-04  2.169586e-04  2.268898e-04
## ASV7832     -2.411152e-03 -2.522943e-03 -2.639787e-03 -2.761904e-03
## ASV1915     -3.112431e-04 -3.251314e-04 -3.396025e-04 -3.546781e-04
## ASV0055     -2.067851e-04 -2.169824e-04 -2.276965e-04 -2.389546e-04
## ASV0032      1.030459e-04  1.073836e-04  1.118765e-04  1.165275e-04
## ASV2977     -3.407138e-03 -3.564284e-03 -3.728447e-03 -3.899920e-03
## ASV0466      2.791067e-03  2.914667e-03  3.043305e-03  3.177148e-03
## ASV3866      1.855833e-03  1.942996e-03  2.034196e-03  2.129613e-03
## ASV0040      6.739644e-04  7.052703e-04  7.379936e-04  7.721952e-04
## ASV0496     -1.384547e-04 -1.469973e-04 -1.561223e-04 -1.658725e-04
## ASV0052      5.655633e-04  5.918618e-04  6.193535e-04  6.480895e-04
## ASV3828     -2.016496e-03 -2.105629e-03 -2.198392e-03 -2.294908e-03
## ASV1930      1.024065e-03  1.070342e-03  1.118589e-03  1.168881e-03
## ASV2126      1.735896e-03  1.815247e-03  1.898072e-03  1.984508e-03
## ASV0793      2.105201e-03  2.203804e-03  2.306947e-03  2.414830e-03
## ASV0299     -4.085428e-05 -4.280277e-05 -4.484760e-05 -4.699415e-05
## ASV0208      1.526417e-03  1.597287e-03  1.671363e-03  1.748784e-03
## ASV0511     -6.444724e-04 -6.728074e-04 -7.022751e-04 -7.329102e-04
## ASV1123     -1.945342e-03 -2.031273e-03 -2.120690e-03 -2.213706e-03
## ASV0099      5.454326e-05  5.731558e-05  6.023689e-05  6.331592e-05
## ASV0752     -1.073994e-03 -1.125097e-03 -1.178625e-03 -1.234691e-03
## ASV0883      1.475319e-03  1.545309e-03  1.618600e-03  1.695347e-03
## ASV0683      1.935179e-03  2.026342e-03  2.121750e-03  2.221594e-03
## ASV4117     -3.105951e-03 -3.249990e-03 -3.400537e-03 -3.557874e-03
## ASV2172      2.114583e-04  2.203191e-04  2.294904e-04  2.389769e-04
## ASV0330     -5.784997e-04 -6.055099e-04 -6.337562e-04 -6.632929e-04
## ASV0728      2.875613e-03  3.008213e-03  3.146720e-03  3.291377e-03
## ASV0499      7.521954e-04  7.877108e-04  8.248881e-04  8.638036e-04
## ASV0120     -1.274517e-03 -1.333373e-03 -1.394859e-03 -1.459085e-03
## ASV1446      1.019002e-03  1.062115e-03  1.106796e-03  1.153078e-03
## ASV17171    -2.466214e-03 -2.579648e-03 -2.698125e-03 -2.821854e-03
## ASV0533      1.787260e-04  1.874212e-04  1.965466e-04  2.061238e-04
## ASV2495     -5.813057e-04 -6.101909e-04 -6.405664e-04 -6.725138e-04
## ASV5582      1.174721e-03  1.225477e-03  1.278180e-03  1.332880e-03
## ASV1488      4.400826e-04  4.599107e-04  4.805778e-04  5.021141e-04
## ASV0682      5.469423e-04  5.728738e-04  6.000280e-04  6.284618e-04
## ASV0068     -9.637936e-04 -1.008437e-03 -1.055089e-03 -1.103834e-03
## ASV1987     -2.365401e-03 -2.478201e-03 -2.596377e-03 -2.720182e-03
## ASV0035     -1.640661e-04 -1.729848e-04 -1.824309e-04 -1.924386e-04
## ASV7192     -1.506381e-03 -1.574824e-03 -1.646227e-03 -1.720705e-03
## ASV0873      9.630001e-05  7.496700e-05  5.036257e-05  2.214805e-05
## ASV4749     -3.592283e-06 -8.027645e-06 -1.306088e-05 -1.875403e-05
## ASV2174      1.068559e-03  1.115134e-03  1.163533e-03  1.213810e-03
## ASV1476     -1.052884e-03 -1.102660e-03 -1.154776e-03 -1.209340e-03
## ASV0740     -2.991006e-03 -3.132328e-03 -3.280272e-03 -3.435143e-03
## ASV0170     -5.909987e-04 -6.183886e-04 -6.470128e-04 -6.769237e-04
## ASV2466     -2.694505e-03 -2.819352e-03 -2.949828e-03 -3.086175e-03
## ASV1709      1.002623e-03  1.047655e-03  1.094597e-03  1.143522e-03
## ASV6170     -4.194210e-03 -4.390916e-03 -4.596705e-03 -4.811984e-03
## ASV3673      2.052426e-03  2.149376e-03  2.250866e-03  2.357106e-03
## ASV1745     -5.246229e-04 -5.500613e-04 -5.767512e-04 -6.047554e-04
##                                                                    
## (Intercept)  1.720319e-02  1.799690e-02  1.882599e-02  1.969190e-02
## ASV1236      3.426164e-03  3.579656e-03  3.739587e-03  3.906188e-03
## ASV0421      3.730031e-04  3.927303e-04  4.135694e-04  4.355873e-04
## ASV0691     -2.702747e-03 -2.817791e-03 -2.937098e-03 -3.060771e-03
## ASV0899      2.965725e-03  3.099201e-03  3.238317e-03  3.383277e-03
## ASV1004      6.854603e-03  7.162598e-03  7.483580e-03  7.818021e-03
## ASV1041     -2.821659e-03 -2.948023e-03 -3.079663e-03 -3.216763e-03
## ASV1058      4.279906e-03  4.471928e-03  4.672026e-03  4.880491e-03
## ASV12542     1.666718e-03  1.740293e-03  1.816850e-03  1.896488e-03
## ASV1294      3.981898e-03  4.160752e-03  4.347146e-03  4.541353e-03
## ASV13113     1.308245e-03  1.370805e-03  1.436364e-03  1.505069e-03
## ASV1318      3.971251e-03  4.149525e-03  4.335303e-03  4.528855e-03
## ASV2269     -6.880564e-03 -7.188759e-03 -7.509852e-03 -7.844303e-03
## ASV2542      3.317226e-03  3.471953e-03  3.633749e-03  3.802922e-03
## ASV2660     -2.741035e-03 -2.863301e-03 -2.990640e-03 -3.123226e-03
## ASV2737      9.563808e-04  9.977704e-04  1.040762e-03  1.085402e-03
## ASV2840      3.670459e-03  3.831459e-03  3.998875e-03  4.172904e-03
## ASV3053      1.874767e-02  1.957683e-02  2.043975e-02  2.133755e-02
## ASV3077      1.194854e-03  1.247845e-03  1.303010e-03  1.360422e-03
## ASV3134      2.094888e-03  2.193960e-03  2.297683e-03  2.406274e-03
## ASV3140      2.860545e-03  2.992279e-03  3.129869e-03  3.273557e-03
## ASV3579      9.978414e-04  1.046570e-03  1.097724e-03  1.151428e-03
## ASV6119     -1.882886e-03 -1.967210e-03 -2.055063e-03 -2.146568e-03
## ASV7557     -3.825867e-03 -3.997179e-03 -4.175655e-03 -4.361551e-03
## ASV8422      9.564451e-04  9.987944e-04  1.042874e-03  1.088742e-03
## ASV1086     -1.516885e-04 -1.579786e-04 -1.644871e-04 -1.712179e-04
## ASV1310      1.832633e-03  1.914821e-03  2.000458e-03  2.089669e-03
## ASV15750    -2.520979e-04 -2.629313e-04 -2.741739e-04 -2.858360e-04
## ASV16905    -7.867266e-04 -8.219538e-04 -8.586544e-04 -8.968805e-04
## ASV2033      3.324060e-03  3.480303e-03  3.643784e-03  3.814828e-03
## ASV2089      1.658638e-03  1.732964e-03  1.810404e-03  1.891068e-03
## ASV2127      5.386268e-03  5.627815e-03  5.879505e-03  6.141704e-03
## ASV2725      4.320407e-03  4.512070e-03  4.711588e-03  4.919225e-03
## ASV2804     -1.628508e-03 -1.701422e-03 -1.777385e-03 -1.856505e-03
## ASV3075      3.553582e-03  3.716093e-03  3.885744e-03  4.062822e-03
## ASV3327      4.895104e-03  5.122974e-03  5.361204e-03  5.610242e-03
## ASV3342      4.211710e-03  4.406830e-03  4.610737e-03  4.823807e-03
## ASV3532     -4.655711e-03 -4.869637e-03 -5.093040e-03 -5.326310e-03
## ASV3600      2.162439e-03  2.262131e-03  2.366270e-03  2.475041e-03
## ASV4013      4.047293e-03  4.231062e-03  4.422760e-03  4.622694e-03
## ASV4136      4.336042e-03  4.528712e-03  4.729317e-03  4.938131e-03
## ASV4195      1.662154e-02  1.736560e-02  1.814077e-02  1.894814e-02
## ASV4407     -6.421286e-03 -6.708687e-03 -7.008098e-03 -7.319942e-03
## ASV4717      1.127424e-03  1.175821e-03  1.226053e-03  1.278167e-03
## ASV6794      2.671590e-03  2.788935e-03  2.910987e-03  3.037899e-03
## ASV8324     -3.294920e-03 -3.442394e-03 -3.596030e-03 -3.756047e-03
## ASV8981     -8.780462e-05 -9.039810e-05 -9.297171e-05 -9.551213e-05
## ASV9859      1.119030e-03  1.174319e-03  1.232422e-03  1.293489e-03
## ASV0936      3.174699e-03  3.321945e-03  3.475831e-03  3.636639e-03
## ASV12683    -1.530964e-06 -2.058284e-06 -2.648774e-06 -3.308256e-06
## ASV1293      2.138061e-03  2.233612e-03  2.333143e-03  2.436797e-03
## ASV13055    -5.493672e-05 -5.641697e-05 -5.786518e-05 -5.927098e-05
## ASV17063    -1.708907e-03 -1.785348e-03 -1.864979e-03 -1.947913e-03
## ASV2228      1.393483e-03  1.455805e-03  1.520727e-03  1.588340e-03
## ASV2769      2.126197e-04  2.236413e-04  2.352644e-04  2.475237e-04
## ASV2803      1.515147e-03  1.581308e-03  1.650081e-03  1.721547e-03
## ASV2896      1.196168e-03  1.251948e-03  1.310280e-03  1.371276e-03
## ASV3062      1.434149e-03  1.503296e-03  1.575806e-03  1.651845e-03
## ASV3107      2.232017e-03  2.335493e-03  2.443638e-03  2.556653e-03
## ASV3265      3.060047e-03  3.196567e-03  3.338750e-03  3.486795e-03
## ASV3666      3.032024e-05  3.152353e-05  3.276074e-05  3.403128e-05
## ASV4497      1.049425e-03  1.096677e-03  1.145930e-03  1.197260e-03
## ASV6914     -1.531228e-04 -1.609158e-04 -1.691242e-04 -1.777715e-04
## ASV0576     -3.671381e-03 -3.830711e-03 -3.996243e-03 -4.168155e-03
## ASV0673      4.037447e-03  4.220278e-03  4.410951e-03  4.609762e-03
## ASV0772      1.872059e-03  1.957304e-03  2.046252e-03  2.139050e-03
## ASV0862      1.646219e-04  1.759051e-04  1.880290e-04  2.010586e-04
## ASV0898      1.443940e-03  1.512176e-03  1.583605e-03  1.658372e-03
## ASV0910      1.671690e-03  1.749511e-03  1.830873e-03  1.915929e-03
## ASV0964     -1.385623e-03 -1.446348e-03 -1.509490e-03 -1.575123e-03
## ASV10059     1.184080e-03  1.240518e-03  1.299644e-03  1.361585e-03
## ASV10263    -2.603180e-03 -2.719733e-03 -2.841161e-03 -2.967637e-03
## ASV1088      2.984758e-03  3.122719e-03  3.266876e-03  3.417492e-03
## ASV1101      3.723060e-03  3.889391e-03  4.062642e-03  4.243058e-03
## ASV1183      9.794470e-04  1.024440e-03  1.071425e-03  1.120482e-03
## ASV11956     9.586255e-04  1.000097e-03  1.043171e-03  1.087892e-03
## ASV12774     5.981671e-05  6.134744e-05  6.283281e-05  6.426064e-05
## ASV1321      4.311281e-03  4.513142e-03  4.724291e-03  4.945143e-03
## ASV13793    -1.794822e-03 -1.875176e-03 -1.958890e-03 -2.046083e-03
## ASV14482     1.161266e-04  1.208892e-04  1.258140e-04  1.309039e-04
## ASV15483     7.333233e-04  7.674007e-04  8.030217e-04  8.402524e-04
## ASV2062      3.433574e-03  3.589192e-03  3.751503e-03  3.920764e-03
## ASV2132      2.791602e-03  2.921037e-03  3.056309e-03  3.197666e-03
## ASV2413      2.659682e-03  2.779027e-03  2.903396e-03  3.032969e-03
## ASV2490      8.212671e-03  8.575112e-03  8.952236e-03  9.344520e-03
## ASV2594      1.018910e-03  1.065764e-03  1.114703e-03  1.165814e-03
## ASV2822     -4.736810e-03 -4.948955e-03 -5.169979e-03 -5.400196e-03
## ASV2863      5.046810e-03  5.271129e-03  5.504693e-03  5.747819e-03
## ASV2910      1.844816e-03  1.927293e-03  2.013210e-03  2.102689e-03
## ASV2980      2.052514e-03  2.145749e-03  2.243011e-03  2.344456e-03
## ASV3307      3.768500e-03  3.937222e-03  4.113000e-03  4.296084e-03
## ASV3474      2.465189e-03  2.581457e-03  2.703150e-03  2.830516e-03
## ASV3502      2.603780e-03  2.723093e-03  2.847660e-03  2.977691e-03
## ASV4236      3.864361e-03  4.034184e-03  4.210809e-03  4.394450e-03
## ASV4842     -4.097462e-04 -4.291011e-04 -4.493504e-04 -4.705326e-04
## ASV4894     -1.795248e-03 -1.875644e-03 -1.959405e-03 -2.046649e-03
## ASV5290      1.417311e-03  1.482861e-03  1.551351e-03  1.622904e-03
## ASV5501      8.681759e-04  9.079297e-04  9.494367e-04  9.927691e-04
## ASV5795      9.519715e-04  9.960971e-04  1.042211e-03  1.090398e-03
## ASV5987     -5.014588e-03 -5.239191e-03 -5.473196e-03 -5.716938e-03
## ASV6267     -5.649893e-03 -5.902910e-03 -6.166514e-03 -6.441082e-03
## ASV6862      2.274179e-03  2.374606e-03  2.479111e-03  2.587827e-03
## ASV7145      1.006634e-03  1.050494e-03  1.096086e-03  1.143465e-03
## ASV7673     -1.795145e-03 -1.875533e-03 -1.959285e-03 -2.046520e-03
## ASV7789      8.731904e-04  9.160554e-04  9.610752e-04  1.008362e-03
## ASV7809      5.415450e-05  5.802490e-05  6.219331e-05  6.668331e-05
## ASV8002     -2.267160e-03 -2.368684e-03 -2.474455e-03 -2.584626e-03
## ASV8205      9.439263e-04  9.874446e-04  1.032904e-03  1.080386e-03
## ASV9155     -5.782269e-04 -6.037185e-04 -6.302384e-04 -6.578194e-04
## ASV9221      2.214090e-04  2.338617e-04  2.470782e-04  2.611091e-04
## ASV9311     -3.636777e-03 -3.799618e-03 -3.969273e-03 -4.145982e-03
## ASV9557     -2.485226e-03 -2.596486e-03 -2.712401e-03 -2.833133e-03
## ASV9936     -5.011316e-03 -5.235629e-03 -5.469321e-03 -5.712724e-03
## ASV1445      3.025937e-03  3.165556e-03  3.311409e-03  3.463756e-03
## ASV4232      1.136868e-03  1.191040e-03  1.247797e-03  1.307262e-03
## ASV6479      3.937041e-04  4.149407e-04  4.374089e-04  4.611857e-04
## ASV0142     -2.162811e-03 -2.259124e-03 -2.359419e-03 -2.463834e-03
## ASV0378      9.683101e-04  1.014485e-03  1.062860e-03  1.113541e-03
## ASV1122      2.925589e-03  3.061247e-03  3.203025e-03  3.351183e-03
## ASV0123     -1.910498e-03 -1.995456e-03 -2.083915e-03 -2.175995e-03
## ASV2064      9.840587e-04  1.026476e-03  1.070512e-03  1.116207e-03
## ASV4459     -1.397000e-04 -1.453126e-04 -1.511021e-04 -1.570699e-04
## ASV0448      7.741139e-04  8.110691e-04  8.497886e-04  8.903562e-04
## ASV0397      1.726099e-03  1.804868e-03  1.887074e-03  1.972853e-03
## ASV0485      2.010354e-03  2.101209e-03  2.195949e-03  2.294720e-03
## ASV1566      2.956510e-03  3.091168e-03  3.231674e-03  3.378259e-03
## ASV1365      2.519896e-03  2.635683e-03  2.756590e-03  2.882826e-03
## ASV1065      3.582684e-03  3.746990e-03  3.918541e-03  4.097629e-03
## ASV0722     -1.858321e-04 -1.945906e-04 -2.037592e-04 -2.133568e-04
## ASV12660    -2.072058e-03 -2.163881e-03 -2.259465e-03 -2.358937e-03
## ASV0223      5.549855e-04  5.801401e-04  6.063782e-04  6.337414e-04
## ASV0229      8.422298e-04  8.813413e-04  9.222242e-04  9.649548e-04
## ASV0877      3.599801e-04  3.753919e-04  3.913746e-04  4.079404e-04
## ASV0983      1.997296e-03  2.087203e-03  2.180918e-03  2.278579e-03
## ASV0626      2.024770e-04  2.141946e-04  2.266505e-04  2.398943e-04
## ASV4146      9.839500e-05  1.028138e-04  1.074116e-04  1.121930e-04
## ASV4175     -2.446249e-03 -2.559456e-03 -2.677748e-03 -2.801340e-03
## ASV2082     -1.077008e-03 -1.131594e-03 -1.189077e-03 -1.249623e-03
## ASV2272      1.165928e-03  1.219659e-03  1.275787e-03  1.334412e-03
## ASV2245     -1.745372e-03 -1.826483e-03 -1.911267e-03 -1.999881e-03
## ASV0590     -1.008588e-03 -1.061142e-03 -1.116601e-03 -1.175137e-03
## ASV0217      7.353255e-05  8.040041e-05  8.789258e-05  9.606343e-05
## ASV0416      1.351042e-03  1.408781e-03  1.468676e-03  1.530781e-03
## ASV1056      1.683435e-03  1.762530e-03  1.845285e-03  1.931866e-03
## ASV7777     -2.383326e-03 -2.493131e-03 -2.607827e-03 -2.727620e-03
## ASV0455      4.283245e-04  4.479448e-04  4.684275e-04  4.898073e-04
## ASV0604      1.105778e-03  1.158222e-03  1.213138e-03  1.270640e-03
## ASV6100     -1.638585e-03 -1.714798e-03 -1.794474e-03 -1.877763e-03
## ASV11359    -3.530042e-03 -3.692749e-03 -3.862703e-03 -4.040204e-03
## ASV6604      4.867140e-04  5.097110e-04  5.337844e-04  5.589832e-04
## ASV5004     -1.257335e-03 -1.314939e-03 -1.375080e-03 -1.437861e-03
## ASV1483     -5.422297e-04 -5.669482e-04 -5.927426e-04 -6.196552e-04
## ASV9773     -1.588655e-03 -1.662168e-03 -1.738986e-03 -1.819247e-03
## ASV4059     -9.725853e-06 -7.534930e-06 -5.003258e-06 -2.094691e-06
## ASV1193      1.925185e-03  2.013133e-03  2.104927e-03  2.200718e-03
## ASV4610     -3.213146e-04 -3.323119e-04 -3.434612e-04 -3.547400e-04
## ASV0742     -1.975805e-04 -2.035769e-04 -2.095577e-04 -2.154974e-04
## ASV1502     -7.735354e-05 -8.280788e-05 -8.867875e-05 -9.499901e-05
## ASV0195      5.227729e-05  5.349191e-05  5.465339e-05  5.575018e-05
## ASV1213      1.370955e-03  1.430631e-03  1.492647e-03  1.557070e-03
## ASV1648     -1.472165e-03 -1.540532e-03 -1.611998e-03 -1.686696e-03
## ASV6984     -1.377144e-03 -1.441146e-03 -1.508055e-03 -1.577996e-03
## ASV0396     -8.458421e-05 -8.714094e-05 -8.969199e-05 -9.222692e-05
## ASV4297      1.982542e-03  2.070069e-03  2.161141e-03  2.255874e-03
## ASV2622      3.064725e-03  3.202171e-03  3.345392e-03  3.494597e-03
## ASV3512      1.169175e-03  1.226601e-03  1.286918e-03  1.350279e-03
## ASV2411      2.065973e-03  2.163257e-03  2.265067e-03  2.371608e-03
## ASV2291     -8.686888e-04 -9.146074e-04 -9.631140e-04 -1.014365e-03
## ASV0807      2.835202e-03  2.964786e-03  3.100040e-03  3.241191e-03
## ASV1292      6.944801e-04  7.241525e-04  7.549351e-04  7.868550e-04
## ASV1035      2.614751e-03  2.731135e-03  2.852337e-03  2.978524e-03
## ASV0070      1.655229e-05  1.856565e-05  2.078545e-05  2.323103e-05
## ASV0255      2.496428e-04  2.603637e-04  2.714879e-04  2.830251e-04
## ASV0057     -7.226226e-04 -7.541203e-04 -7.868547e-04 -8.208620e-04
## ASV0077     -1.555001e-04 -1.618057e-04 -1.683128e-04 -1.750225e-04
## ASV0625      1.507538e-03  1.574240e-03  1.643660e-03  1.715886e-03
## ASV2464      1.026588e-02  1.071825e-02  1.118893e-02  1.167851e-02
## ASV1315      2.689469e-03  2.816608e-03  2.949707e-03  3.089040e-03
## ASV2673      2.306382e-03  2.415539e-03  2.529823e-03  2.649473e-03
## ASV2161      9.759162e-04  1.021976e-03  1.070191e-03  1.120659e-03
## ASV0337     -5.608067e-04 -5.868155e-04 -6.139975e-04 -6.424027e-04
## ASV7680     -3.658229e-03 -3.828289e-03 -4.006060e-03 -4.191877e-03
## ASV0611      2.042657e-03  2.137723e-03  2.237113e-03  2.341015e-03
## ASV3118     -2.112043e-03 -2.212412e-03 -2.317532e-03 -2.427625e-03
## ASV1284      7.956684e-04  8.238025e-04  8.524008e-04  8.814105e-04
## ASV0889      1.554707e-03  1.624770e-03  1.697813e-03  1.773945e-03
## ASV4649     -7.760353e-04 -8.117056e-04 -8.489569e-04 -8.878544e-04
## ASV1108     -1.576803e-03 -1.652529e-03 -1.731915e-03 -1.815139e-03
## ASV0738      8.633344e-04  9.066801e-04  9.522886e-04  1.000284e-03
## ASV0473     -1.721151e-04 -1.815481e-04 -1.915342e-04 -2.021077e-04
## ASV0598     -4.382667e-04 -4.609546e-04 -4.848873e-04 -5.101385e-04
## ASV0429      1.156467e-03  1.207961e-03  1.261579e-03  1.317394e-03
## ASV1549      2.127574e-03  2.228386e-03  2.333945e-03  2.444473e-03
## ASV1203      1.689715e-03  1.766131e-03  1.845815e-03  1.928892e-03
## ASV4532      7.497795e-05  7.778960e-05  8.067078e-05  8.361984e-05
## ASV0274      2.900996e-04  3.043225e-04  3.192553e-04  3.349340e-04
## ASV0163     -1.310565e-03 -1.368360e-03 -1.428495e-03 -1.491044e-03
## ASV1298      1.455109e-04  1.513711e-04  1.574205e-04  1.636613e-04
## ASV9424     -2.833992e-03 -2.966233e-03 -3.104523e-03 -3.249125e-03
## ASV0412      2.934090e-03  3.066089e-03  3.203676e-03  3.347056e-03
## ASV0284      6.206424e-04  6.466432e-04  6.735639e-04  7.014211e-04
## ASV0620     -5.904321e-04 -6.201065e-04 -6.513303e-04 -6.841884e-04
## ASV0153     -2.844593e-03 -2.979356e-03 -3.120461e-03 -3.268200e-03
## ASV0498      1.006686e-03  1.053547e-03  1.102536e-03  1.153741e-03
## ASV0097      5.588594e-04  5.853221e-04  6.130301e-04  6.420409e-04
## ASV0104     -3.975923e-03 -4.156967e-03 -4.345870e-03 -4.542937e-03
## ASV1282      1.376833e-03  1.437931e-03  1.501529e-03  1.567708e-03
## ASV3883     -1.078590e-03 -1.131184e-03 -1.186383e-03 -1.244321e-03
## ASV0801      5.370270e-04  5.619928e-04  5.880896e-04  6.153658e-04
## ASV1611     -2.537565e-03 -2.656861e-03 -2.781691e-03 -2.912305e-03
## ASV0227     -4.507816e-04 -4.741099e-04 -4.987109e-04 -5.246583e-04
## ASV0833      8.649037e-04  9.049780e-04  9.468552e-04  9.906114e-04
## ASV0718      3.871633e-03  4.050346e-03  4.237050e-03  4.432081e-03
## ASV1139      5.108085e-04  5.310395e-04  5.518641e-04  5.732788e-04
## ASV0766     -5.360902e-04 -5.623050e-04 -5.898241e-04 -6.187134e-04
## ASV2091      3.165449e-03  3.305641e-03  3.451554e-03  3.603377e-03
## ASV1238     -2.873493e-03 -3.007756e-03 -3.148183e-03 -3.295047e-03
## ASV9193     -2.666026e-04 -2.817393e-04 -2.978180e-04 -3.149028e-04
## ASV0290      4.173771e-04  4.345763e-04  4.523587e-04  4.707325e-04
## ASV0231      1.155016e-03  1.206973e-03  1.261127e-03  1.317559e-03
## ASV0185      6.628139e-04  6.959774e-04  7.308627e-04  7.675638e-04
## ASV2330      1.329236e-03  1.387391e-03  1.447851e-03  1.510687e-03
## ASV3119     -6.007029e-04 -6.306045e-04 -6.620440e-04 -6.951043e-04
## ASV2368     -1.471331e-03 -1.541152e-03 -1.614278e-03 -1.690862e-03
## ASV0122     -7.170754e-04 -7.495736e-04 -7.834693e-04 -8.188160e-04
## ASV1044      1.828213e-03  1.914189e-03  2.004156e-03  2.098294e-03
## ASV0160     -7.736069e-04 -8.075092e-04 -8.427619e-04 -8.794067e-04
## ASV0326      2.027411e-04  2.121559e-04  2.219953e-04  2.322772e-04
## ASV1388      3.718197e-03  3.887237e-03  4.063589e-03  4.247537e-03
## ASV0792      2.766173e-03  2.889745e-03  3.018460e-03  3.152500e-03
## ASV0036     -8.532234e-04 -8.936744e-04 -9.360303e-04 -9.803792e-04
## ASV2125      2.656042e-03  2.777378e-03  2.904019e-03  3.036174e-03
## ASV1075     -3.998165e-05 -4.180332e-05 -4.370605e-05 -4.569345e-05
## ASV0390      1.409172e-03  1.475928e-03  1.545830e-03  1.619024e-03
## ASV3790     -2.007340e-03 -2.100569e-03 -2.198019e-03 -2.299871e-03
## ASV1535     -5.730802e-04 -6.014295e-04 -6.312218e-04 -6.625335e-04
## ASV0263      2.462333e-03  2.575551e-03  2.693789e-03  2.817252e-03
## ASV0675      3.690316e-03  3.862881e-03  4.043367e-03  4.232124e-03
## ASV3348      2.972479e-04  3.116967e-04  3.268579e-04  3.427673e-04
## ASV0058     -1.100115e-03 -1.150012e-03 -1.202056e-03 -1.256330e-03
## ASV4142      1.547325e-03  1.616319e-03  1.688167e-03  1.762967e-03
## ASV0059     -8.869183e-04 -9.269352e-04 -9.686548e-04 -1.012140e-03
## ASV0013     -1.572352e-03 -1.644545e-03 -1.719929e-03 -1.798633e-03
## ASV0033     -7.419982e-04 -7.770808e-04 -8.138072e-04 -8.522529e-04
## ASV4354     -9.260692e-04 -9.686239e-04 -1.013069e-03 -1.059482e-03
## ASV0022     -6.266724e-04 -6.562776e-04 -6.872682e-04 -7.197076e-04
## ASV0134     -5.935963e-04 -6.223453e-04 -6.525040e-04 -6.841426e-04
## ASV0415      9.373821e-05  9.875516e-05  1.040566e-04  1.096593e-04
## ASV10103    -3.486671e-03 -3.649775e-03 -3.820371e-03 -3.998790e-03
## ASV1613      2.622082e-03  2.739327e-03  2.861461e-03  2.988653e-03
## ASV0135     -3.385057e-04 -3.532435e-04 -3.685577e-04 -3.844650e-04
## ASV0469     -3.378811e-03 -3.531408e-03 -3.690520e-03 -3.856393e-03
## ASV0471      2.051359e-03  2.145350e-03  2.243476e-03  2.345905e-03
## ASV0451     -3.267455e-04 -3.440474e-04 -3.623266e-04 -3.816424e-04
## ASV0747      1.165347e-03  1.219275e-03  1.275624e-03  1.334496e-03
## ASV1314     -1.164741e-03 -1.220105e-03 -1.278095e-03 -1.338836e-03
## ASV0425     -4.193923e-03 -4.380474e-03 -4.574716e-03 -4.776912e-03
## ASV0559     -1.032835e-03 -1.079941e-03 -1.129107e-03 -1.180418e-03
## ASV0148     -2.397847e-04 -2.492254e-04 -2.589363e-04 -2.689146e-04
## ASV0129      2.293866e-04  2.428810e-04  2.572503e-04  2.725561e-04
## ASV1072      2.807942e-04  2.926618e-04  3.049572e-04  3.176886e-04
## ASV2390      2.154297e-03  2.248768e-03  2.346997e-03  2.449100e-03
## ASV0548      1.412138e-03  1.476693e-03  1.544075e-03  1.614395e-03
## ASV0168     -7.267395e-04 -7.595127e-04 -7.936799e-04 -8.292928e-04
## ASV0066     -8.178077e-04 -8.549226e-04 -8.936362e-04 -9.340095e-04
## ASV0468     -4.319493e-04 -4.518535e-04 -4.726450e-04 -4.943608e-04
## ASV0172     -2.484102e-04 -2.588516e-04 -2.696643e-04 -2.808551e-04
## ASV0236     -6.099964e-05 -5.998228e-05 -5.856498e-05 -5.669882e-05
## ASV0250      1.137517e-03  1.193117e-03  1.251491e-03  1.312784e-03
## ASV0338      5.427774e-04  5.685217e-04  5.954750e-04  6.236923e-04
## ASV0450     -9.877359e-05 -1.041600e-04 -1.098634e-04 -1.159037e-04
## ASV0377      1.022104e-03  1.068379e-03  1.116638e-03  1.166956e-03
## ASV1022     -4.397314e-05 -4.584040e-05 -4.777362e-05 -4.977361e-05
## ASV6174     -2.073165e-05 -2.207863e-05 -2.352495e-05 -2.507874e-05
## ASV0786     -1.356559e-04 -1.435043e-04 -1.518457e-04 -1.607129e-04
## ASV0053     -1.102201e-03 -1.152996e-03 -1.206054e-03 -1.261466e-03
## ASV0697     -6.741216e-04 -7.042391e-04 -7.356124e-04 -7.682863e-04
## ASV0785      1.415687e-03  1.479818e-03  1.546703e-03  1.616445e-03
## ASV1967     -1.408318e-03 -1.471687e-03 -1.537743e-03 -1.606588e-03
## ASV0385      4.688073e-04  4.912200e-04  5.147032e-04  5.393074e-04
## ASV0295      7.894928e-05  8.375279e-05  8.887917e-05  9.435186e-05
## ASV0072     -1.102086e-03 -1.151500e-03 -1.202986e-03 -1.256618e-03
## ASV0157     -1.469292e-04 -1.519123e-04 -1.569495e-04 -1.620274e-04
## ASV0501      2.378775e-03  2.488686e-03  2.603518e-03  2.723476e-03
## ASV10729    -2.986878e-03 -3.125596e-03 -3.270592e-03 -3.422136e-03
## ASV1470      1.539689e-03  1.606872e-03  1.676699e-03  1.749249e-03
## ASV0050     -2.588477e-03 -2.705994e-03 -2.828580e-03 -2.956429e-03
## ASV0411     -5.802582e-04 -6.076053e-04 -6.362267e-04 -6.661803e-04
## ASV0549      9.341944e-04  9.778488e-04  1.023503e-03  1.071246e-03
## ASV0184      3.139036e-04  3.281584e-04  3.430308e-04  3.585452e-04
## ASV0705      6.222757e-04  6.501734e-04  6.792403e-04  7.095178e-04
## ASV1715      1.310187e-03  1.370491e-03  1.433474e-03  1.499246e-03
## ASV0603      2.033412e-04  2.129118e-04  2.229300e-04  2.334169e-04
## ASV0826      2.215887e-03  2.316909e-03  2.422329e-03  2.532322e-03
## ASV0034     -7.116076e-04 -7.435823e-04 -7.769047e-04 -8.116235e-04
## ASV0838      5.051730e-04  5.242675e-04  5.438163e-04  5.638009e-04
## ASV0614     -6.068677e-04 -6.344926e-04 -6.633174e-04 -6.933893e-04
## ASV0014     -1.607020e-03 -1.680491e-03 -1.757179e-03 -1.837213e-03
## ASV0585      1.907431e-04  1.963266e-04  2.018632e-04  2.073240e-04
## ASV0016     -1.678770e-03 -1.755518e-03 -1.835628e-03 -1.919232e-03
## ASV5394     -1.256080e-03 -1.314131e-03 -1.374784e-03 -1.438146e-03
## ASV0666      2.758123e-03  2.881180e-03  3.009347e-03  3.142802e-03
## ASV2085      6.537970e-04  6.784586e-04  7.037172e-04  7.295523e-04
## ASV0003     -1.144902e-03 -1.197204e-03 -1.251792e-03 -1.308758e-03
## ASV0346      5.711180e-04  5.982886e-04  6.267457e-04  6.565491e-04
## ASV0267     -9.108116e-06 -8.484224e-06 -7.735062e-06 -6.846488e-06
## ASV0353      9.101314e-04  9.528922e-04  9.976336e-04  1.044445e-03
## ASV2419      2.467736e-03  2.579716e-03  2.696525e-03  2.818347e-03
## ASV0447      1.333656e-03  1.396491e-03  1.462249e-03  1.531064e-03
## ASV0654      1.987175e-03  2.078164e-03  2.173150e-03  2.272293e-03
## ASV0151      2.598772e-04  2.730215e-04  2.868612e-04  3.014355e-04
## ASV0065     -7.702684e-04 -8.052468e-04 -8.417351e-04 -8.797915e-04
## ASV0527      1.892376e-03  1.978688e-03  2.068761e-03  2.162745e-03
## ASV4055     -2.952473e-04 -3.096473e-04 -3.247664e-04 -3.406419e-04
## ASV0166     -9.547609e-04 -9.973570e-04 -1.041721e-03 -1.087915e-03
## ASV0417     -3.932889e-04 -4.102215e-04 -4.277984e-04 -4.460365e-04
## ASV0078     -5.650534e-04 -5.904247e-04 -6.168630e-04 -6.444064e-04
## ASV0322     -1.071989e-04 -1.111364e-04 -1.151493e-04 -1.192303e-04
## ASV0156     -1.335449e-03 -1.397461e-03 -1.462282e-03 -1.530032e-03
## ASV0648     -2.897385e-03 -3.032502e-03 -3.173786e-03 -3.321506e-03
## ASV0407     -2.162878e-04 -2.265937e-04 -2.373909e-04 -2.487026e-04
## ASV2030     -4.861761e-04 -5.080348e-04 -5.308295e-04 -5.545974e-04
## ASV0300      3.444583e-04  3.608424e-04  3.780032e-04  3.959771e-04
## ASV1150      7.614872e-05  8.006505e-05  8.419273e-05  8.854377e-05
## ASV0958      1.063924e-03  1.114620e-03  1.167731e-03  1.223372e-03
## ASV0216     -1.190223e-03 -1.243978e-03 -1.300032e-03 -1.358474e-03
## ASV0446      1.785404e-03  1.868695e-03  1.955787e-03  2.046845e-03
## ASV0367     -1.172108e-03 -1.226252e-03 -1.282821e-03 -1.341915e-03
## ASV0200     -6.974093e-04 -7.295856e-04 -7.631984e-04 -7.983072e-04
## ASV0334     -3.867547e-04 -4.026394e-04 -4.190570e-04 -4.360142e-04
## ASV1311      4.651270e-04  4.849460e-04  5.054982e-04  5.268002e-04
## ASV0458      6.889470e-04  7.179536e-04  7.480044e-04  7.791206e-04
## ASV1371      1.083777e-04  1.137363e-04  1.193656e-04  1.252795e-04
## ASV0418      1.565419e-03  1.634947e-03  1.707334e-03  1.782678e-03
## ASV0004      2.271525e-04  2.371926e-04  2.476406e-04  2.585101e-04
## ASV1943      4.401074e-03  4.583971e-03  4.773271e-03  4.969095e-03
## ASV1495     -2.991518e-04 -3.158354e-04 -3.335320e-04 -3.523085e-04
## ASV0901     -1.312665e-03 -1.374220e-03 -1.438618e-03 -1.505987e-03
## ASV0628      7.078667e-04  7.386479e-04  7.706291e-04  8.038442e-04
## ASV0400      4.282915e-04  4.474558e-04  4.674191e-04  4.882093e-04
## ASV0116     -3.861621e-04 -4.042357e-04 -4.231408e-04 -4.429142e-04
## ASV0788      3.411937e-03  3.571972e-03  3.739402e-03  3.914557e-03
## ASV0117      2.501683e-04  2.622006e-04  2.748154e-04  2.880413e-04
## ASV3137     -8.057213e-05 -8.418094e-05 -8.794087e-05 -9.185729e-05
## ASV0001      2.441174e-04  2.548561e-04  2.660262e-04  2.776412e-04
## ASV1651      6.944986e-04  7.253016e-04  7.573665e-04  7.907359e-04
## ASV1692      2.842398e-03  2.975517e-03  3.114765e-03  3.260415e-03
## ASV0660      1.030462e-03  1.074857e-03  1.120941e-03  1.168757e-03
## ASV0508      5.192084e-05  5.410275e-05  5.636300e-05  5.870319e-05
## ASV1660     -5.673663e-04 -5.952548e-04 -6.245432e-04 -6.553031e-04
## ASV0233      8.805703e-04  9.211578e-04  9.635546e-04  1.007836e-03
## ASV1343     -1.619585e-03 -1.695235e-03 -1.774350e-03 -1.857083e-03
## ASV0209      8.161566e-04  8.521249e-04  8.895441e-04  9.284609e-04
## ASV0193     -9.517476e-04 -9.939559e-04 -1.037891e-03 -1.083611e-03
## ASV0357      3.561720e-04  3.741525e-04  3.930829e-04  4.130167e-04
## ASV0198      7.200858e-04  7.526533e-04  7.866153e-04  8.220246e-04
## ASV0007      2.160292e-04  2.254098e-04  2.351554e-04  2.452764e-04
## ASV1772     -3.224861e-04 -3.362273e-04 -3.504701e-04 -3.652243e-04
## ASV0009      1.789500e-04  1.866107e-04  1.945589e-04  2.028017e-04
## ASV0006     -1.917196e-04 -2.008986e-04 -2.105184e-04 -2.206003e-04
## ASV0011     -6.684219e-04 -6.995280e-04 -7.320477e-04 -7.660423e-04
## ASV0015      1.352645e-04  1.410519e-04  1.470559e-04  1.532818e-04
## ASV0017      1.523569e-04  1.588825e-04  1.656533e-04  1.726756e-04
## ASV0235     -6.170141e-04 -6.458758e-04 -6.760617e-04 -7.076302e-04
## ASV0382      4.829690e-04  5.055687e-04  5.292022e-04  5.539141e-04
## ASV2357      2.014101e-03  2.107715e-03  2.205575e-03  2.307865e-03
## ASV0567     -3.896286e-04 -4.078645e-04 -4.269419e-04 -4.468988e-04
## ASV0165      3.360404e-04  3.516597e-04  3.679866e-04  3.850514e-04
## ASV0005      4.890951e-04  5.114414e-04  5.347645e-04  5.591030e-04
## ASV0384     -5.680396e-05 -5.850853e-05 -6.020334e-05 -6.188000e-05
## ASV0002      9.195124e-05  9.604411e-05  1.003065e-04  1.047443e-04
## ASV3017      2.603855e-03  2.719504e-03  2.839901e-03  2.965208e-03
## ASV0091     -6.584666e-05 -6.880790e-05 -7.189539e-05 -7.511403e-05
## ASV0186     -9.849981e-04 -1.030212e-03 -1.077421e-03 -1.126707e-03
## ASV0370      5.238710e-04  5.475592e-04  5.722595e-04  5.980095e-04
## ASV0018      6.262709e-04  6.549578e-04  6.849055e-04  7.161647e-04
## ASV1377      6.306756e-03  6.588809e-03  6.882634e-03  7.188647e-03
## ASV0019      6.569221e-04  6.870358e-04  7.184752e-04  7.512938e-04
## ASV0023     -4.089981e-04 -4.281644e-04 -4.482136e-04 -4.691850e-04
## ASV2194      6.563260e-04  6.873584e-04  7.198484e-04  7.538637e-04
## ASV1155      2.639993e-03  2.757680e-03  2.880270e-03  3.007936e-03
## ASV0510     -7.123731e-04 -7.429676e-04 -7.747164e-04 -8.076485e-04
## ASV2371     -1.589561e-03 -1.660480e-03 -1.734353e-03 -1.811285e-03
## ASV0024     -5.095302e-04 -5.333470e-04 -5.582555e-04 -5.843037e-04
## ASV2452      1.603981e-03  1.673828e-03  1.746407e-03  1.821798e-03
## ASV2332     -4.558591e-03 -4.763488e-03 -4.977063e-03 -5.199638e-03
## ASV2591      1.169095e-03  1.227673e-03  1.289267e-03  1.354035e-03
## ASV0521      1.035447e-03  1.083789e-03  1.134344e-03  1.187208e-03
## ASV5542      9.909380e-04  1.037286e-03  1.085753e-03  1.136431e-03
## ASV0336     -1.206594e-04 -1.273337e-04 -1.344065e-04 -1.419033e-04
## ASV10102     1.831580e-03  1.917047e-03  2.006414e-03  2.099851e-03
## ASV16823    -2.861780e-03 -2.987007e-03 -3.117226e-03 -3.252595e-03
## ASV3104      1.480519e-02  1.545293e-02  1.612649e-02  1.682668e-02
## ASV0781      2.050519e-03  2.144292e-03  2.242174e-03  2.344329e-03
## ASV10899     1.181889e-03  1.241262e-03  1.303728e-03  1.369454e-03
## ASV11222    -5.035919e-03 -5.256231e-03 -5.485321e-03 -5.723467e-03
## ASV11327    -4.520669e-03 -4.718407e-03 -4.924022e-03 -5.137763e-03
## ASV12458    -5.034366e-03 -5.254539e-03 -5.483480e-03 -5.721463e-03
## ASV1636      2.830529e-03  2.957735e-03  3.090305e-03  3.228434e-03
## ASV1890     -2.328131e-03 -2.426888e-03 -2.529298e-03 -2.635450e-03
## ASV2898      3.794724e-03  3.965375e-03  4.143238e-03  4.328578e-03
## ASV8328      4.096954e-04  4.368944e-04  4.660582e-04  4.973348e-04
## ASV0709     -4.221293e-03 -4.413314e-03 -4.613643e-03 -4.822602e-03
## ASV0856      3.477886e-03  3.642433e-03  3.814697e-03  3.995032e-03
## ASV0909      9.805076e-04  1.032070e-03  1.086518e-03  1.144023e-03
## ASV0937     -2.469997e-03 -2.584955e-03 -2.705153e-03 -2.830821e-03
## ASV11390    -7.184213e-03 -7.498368e-03 -7.825031e-03 -8.164594e-03
## ASV11966     1.696706e-03  1.778440e-03  1.864131e-03  1.953970e-03
## ASV12990     1.248976e-03  1.304824e-03  1.362993e-03  1.423564e-03
## ASV14797     1.853607e-03  1.935710e-03  2.021165e-03  2.110082e-03
## ASV14904    -1.030877e-02 -1.075955e-02 -1.122827e-02 -1.171549e-02
## ASV15304     1.055662e-03  1.108120e-03  1.163254e-03  1.221203e-03
## ASV16696    -3.561468e-03 -3.717184e-03 -3.879098e-03 -4.047404e-03
## ASV1690      5.906564e-03  6.186821e-03  6.480262e-03  6.787489e-03
## ASV2029      4.152917e-03  4.341124e-03  4.537426e-03  4.742133e-03
## ASV2834      5.179397e-03  5.419460e-03  5.670339e-03  5.932494e-03
## ASV4003      4.219551e-03  4.422875e-03  4.636082e-03  4.859657e-03
## ASV4064      2.454497e-03  2.568966e-03  2.688651e-03  2.813780e-03
## ASV4294      1.461687e-03  1.534194e-03  1.610402e-03  1.690505e-03
## ASV4609      1.405587e-03  1.469111e-03  1.535343e-03  1.604383e-03
## ASV6283     -3.329454e-03 -3.475042e-03 -3.626427e-03 -3.783791e-03
## ASV6491     -4.771408e-03 -4.980016e-03 -5.196926e-03 -5.422401e-03
## ASV7453      2.247701e-03  2.356477e-03  2.470561e-03  2.590215e-03
## ASV7959      7.921542e-04  8.336369e-04  8.774154e-04  9.236240e-04
## ASV8219      4.123202e-02  4.303458e-02  4.490888e-02  4.685718e-02
## ASV8547     -4.270874e-03 -4.457556e-03 -4.651665e-03 -4.853434e-03
## ASV9319      1.825297e-03  1.911415e-03  2.001551e-03  2.095886e-03
## ASV9382     -8.355790e-03 -8.720996e-03 -9.100728e-03 -9.495442e-03
## ASV11516    -5.580139e-03 -5.823991e-03 -6.077538e-03 -6.341086e-03
## ASV14377    -4.028542e-03 -4.204560e-03 -4.387576e-03 -4.577806e-03
## ASV1867      3.071151e-03  3.214312e-03  3.363998e-03  3.520494e-03
## ASV1895      1.568322e-03  1.636711e-03  1.707774e-03  1.781588e-03
## ASV3168      1.966356e-03  2.053521e-03  2.144240e-03  2.238628e-03
## ASV4449      1.075354e-02  1.124429e-02  1.175651e-02  1.229106e-02
## ASV6596      2.201507e-03  2.308774e-03  2.421357e-03  2.539526e-03
## ASV7492     -4.410933e-04 -4.548792e-04 -4.686964e-04 -4.824960e-04
## ASV9854     -8.642758e-04 -9.015097e-04 -9.401820e-04 -9.803347e-04
## ASV6296      6.758846e-02  7.054104e-02  7.361094e-02  7.680182e-02
## ASV4201      2.869792e-04  3.067915e-04  3.280827e-04  3.509668e-04
## ASV0552      2.126939e-03  2.225749e-03  2.329032e-03  2.436979e-03
## ASV3671     -1.427146e-03 -1.491596e-03 -1.558816e-03 -1.628916e-03
## ASV3529     -3.979789e-04 -4.109760e-04 -4.240863e-04 -4.372760e-04
## ASV1060      5.625833e-04  5.893105e-04  6.173056e-04  6.466287e-04
## ASV0239     -7.779727e-04 -8.116932e-04 -8.467220e-04 -8.830961e-04
## ASV5711     -3.492882e-03 -3.649861e-03 -3.813490e-03 -3.984017e-03
## ASV4152     -4.912773e-03 -5.138678e-03 -5.374613e-03 -5.620994e-03
## ASV1461      2.506855e-03  2.616206e-03  2.729861e-03  2.847946e-03
## ASV2877      1.299113e-03  1.356320e-03  1.415826e-03  1.477705e-03
## ASV0012      2.221358e-04  2.323215e-04  2.429566e-04  2.540594e-04
## ASV9823      3.265985e-04  3.395141e-04  3.528026e-04  3.664605e-04
## ASV0008      2.372575e-04  2.480794e-04  2.593736e-04  2.711590e-04
## ASV7832     -2.889520e-03 -3.022870e-03 -3.162199e-03 -3.307761e-03
## ASV1915     -3.703808e-04 -3.867335e-04 -4.037602e-04 -4.214853e-04
## ASV0055     -2.507855e-04 -2.632194e-04 -2.762883e-04 -2.900260e-04
## ASV0032      1.213395e-04  1.263149e-04  1.314560e-04  1.367646e-04
## ASV2977     -4.079006e-03 -4.266020e-03 -4.461287e-03 -4.665141e-03
## ASV0466      3.316363e-03  3.461120e-03  3.611587e-03  3.767938e-03
## ASV3866      2.229437e-03  2.333864e-03  2.443100e-03  2.557359e-03
## ASV0040      8.079384e-04  8.452885e-04  8.843138e-04  9.250845e-04
## ASV0496     -1.762938e-04 -1.874357e-04 -1.993514e-04 -2.120980e-04
## ASV0052      6.781234e-04  7.095104e-04  7.423080e-04  7.765758e-04
## ASV3828     -2.395297e-03 -2.499686e-03 -2.608198e-03 -2.720962e-03
## ASV1930      1.221290e-03  1.275892e-03  1.332765e-03  1.391988e-03
## ASV2126      2.074698e-03  2.168788e-03  2.266931e-03  2.369281e-03
## ASV0793      2.527664e-03  2.645667e-03  2.769065e-03  2.898096e-03
## ASV0299     -4.924822e-05 -5.161601e-05 -5.410421e-05 -5.672004e-05
## ASV0208      1.829692e-03  1.914235e-03  2.002568e-03  2.094848e-03
## ASV0511     -7.647474e-04 -7.978215e-04 -8.321670e-04 -8.678181e-04
## ASV1123     -2.310434e-03 -2.410992e-03 -2.515495e-03 -2.624059e-03
## ASV0099      6.656196e-05  6.998494e-05  7.359542e-05  7.740468e-05
## ASV0752     -1.293415e-03 -1.354921e-03 -1.419339e-03 -1.486805e-03
## ASV0883      1.775709e-03  1.859854e-03  1.947958e-03  2.040201e-03
## ASV0683      2.326076e-03  2.435405e-03  2.549799e-03  2.669485e-03
## ASV4117     -3.722291e-03 -3.894088e-03 -4.073580e-03 -4.261091e-03
## ASV2172      2.487827e-04  2.589115e-04  2.693660e-04  2.801479e-04
## ASV0330     -6.941764e-04 -7.264655e-04 -7.602213e-04 -7.955072e-04
## ASV0728      3.442437e-03  3.600159e-03  3.764814e-03  3.936678e-03
## ASV0499      9.045371e-04  9.471715e-04  9.917939e-04  1.038495e-03
## ASV0120     -1.526163e-03 -1.596210e-03 -1.669348e-03 -1.745702e-03
## ASV1446      1.200992e-03  1.250569e-03  1.301835e-03  1.354815e-03
## ASV17171    -2.951052e-03 -3.085944e-03 -3.226762e-03 -3.373747e-03
## ASV0533      2.161758e-04  2.267267e-04  2.378018e-04  2.494276e-04
## ASV2495     -7.061195e-04 -7.414751e-04 -7.786776e-04 -8.178299e-04
## ASV5582      1.389629e-03  1.448477e-03  1.509472e-03  1.572660e-03
## ASV1488      5.245507e-04  5.479192e-04  5.722514e-04  5.975801e-04
## ASV0682      6.582348e-04  6.894089e-04  7.220490e-04  7.562231e-04
## ASV0068     -1.154759e-03 -1.207957e-03 -1.263520e-03 -1.321547e-03
## ASV1987     -2.849883e-03 -2.985759e-03 -3.128101e-03 -3.277214e-03
## ASV0035     -2.030448e-04 -2.142888e-04 -2.262128e-04 -2.388621e-04
## ASV7192     -1.798378e-03 -1.879366e-03 -1.963795e-03 -2.051792e-03
## ASV0873     -1.004428e-05 -4.661334e-05 -8.799132e-05 -1.346459e-04
## ASV4749     -2.517476e-05 -3.239685e-05 -4.050067e-05 -4.957369e-05
## ASV2174      1.266015e-03  1.320202e-03  1.376419e-03  1.434717e-03
## ASV1476     -1.266468e-03 -1.326279e-03 -1.388896e-03 -1.454452e-03
## ASV0740     -3.597258e-03 -3.766951e-03 -3.944568e-03 -4.130471e-03
## ASV0170     -7.081758e-04 -7.408254e-04 -7.749310e-04 -8.105531e-04
## ASV2466     -3.228643e-03 -3.377490e-03 -3.532986e-03 -3.695409e-03
## ASV1709      1.194503e-03  1.247617e-03  1.302944e-03  1.360564e-03
## ASV6170     -5.037175e-03 -5.272719e-03 -5.519076e-03 -5.776722e-03
## ASV3673      2.468312e-03  2.584713e-03  2.706546e-03  2.834060e-03
## ASV1745     -6.341400e-04 -6.649746e-04 -6.973322e-04 -7.312896e-04
##                                                                    
## (Intercept)  2.059616e-02  2.154032e-02  2.252598e-02  2.355480e-02
## ASV1236      4.079697e-03  4.260354e-03  4.448405e-03  4.644103e-03
## ASV0421      4.588552e-04  4.834488e-04  5.094483e-04  5.369391e-04
## ASV0691     -3.188907e-03 -3.321600e-03 -3.458942e-03 -3.601018e-03
## ASV0899      3.534291e-03  3.691572e-03  3.855336e-03  4.025804e-03
## ASV1004      8.166402e-03  8.529214e-03  8.906960e-03  9.300149e-03
## ASV1041     -3.359511e-03 -3.508096e-03 -3.662713e-03 -3.823555e-03
## ASV1058      5.097620e-03  5.323718e-03  5.559095e-03  5.804066e-03
## ASV12542     1.979304e-03  2.065399e-03  2.154873e-03  2.247827e-03
## ASV1294      4.743653e-03  4.954334e-03  5.173685e-03  5.402006e-03
## ASV13113     1.577069e-03  1.652523e-03  1.731598e-03  1.814467e-03
## ASV1318      4.730459e-03  4.940398e-03  5.158958e-03  5.386434e-03
## ASV2269     -8.192577e-03 -8.555149e-03 -8.932501e-03 -9.325124e-03
## ASV2542      3.979795e-03  4.164702e-03  4.357992e-03  4.560026e-03
## ASV2660     -3.261239e-03 -3.404860e-03 -3.554275e-03 -3.709670e-03
## ASV2737      1.131734e-03  1.179804e-03  1.229657e-03  1.281336e-03
## ASV2840      4.353742e-03  4.541587e-03  4.736636e-03  4.939085e-03
## ASV3053      2.227136e-02  2.324232e-02  2.425159e-02  2.530033e-02
## ASV3077      1.420155e-03  1.482286e-03  1.546891e-03  1.614049e-03
## ASV3134      2.519956e-03  2.638966e-03  2.763549e-03  2.893960e-03
## ASV3140      3.423592e-03  3.580231e-03  3.743741e-03  3.914396e-03
## ASV3579      1.207812e-03  1.267013e-03  1.329176e-03  1.394454e-03
## ASV6119     -2.241855e-03 -2.341051e-03 -2.444290e-03 -2.551705e-03
## ASV7557     -4.555123e-03 -4.756637e-03 -4.966358e-03 -5.184559e-03
## ASV8422      1.136456e-03  1.186078e-03  1.237667e-03  1.291284e-03
## ASV1086     -1.781747e-04 -1.853607e-04 -1.927789e-04 -2.004321e-04
## ASV1310      2.182580e-03  2.279319e-03  2.380016e-03  2.484806e-03
## ASV15750    -2.979274e-04 -3.104577e-04 -3.234361e-04 -3.368711e-04
## ASV16905    -9.366854e-04 -9.781230e-04 -1.021249e-03 -1.066118e-03
## ASV2033      3.993774e-03  4.180974e-03  4.376795e-03  4.581617e-03
## ASV2089      1.975070e-03  2.062524e-03  2.153548e-03  2.248260e-03
## ASV2127      6.414784e-03  6.699123e-03  6.995110e-03  7.303138e-03
## ASV2725      5.135249e-03  5.359931e-03  5.593544e-03  5.836367e-03
## ASV2804     -1.938892e-03 -2.024659e-03 -2.113918e-03 -2.206785e-03
## ASV3075      4.247628e-03  4.440469e-03  4.641666e-03  4.851547e-03
## ASV3327      5.870553e-03  6.142619e-03  6.426942e-03  6.724042e-03
## ASV3342      5.046424e-03  5.278992e-03  5.521925e-03  5.775655e-03
## ASV3532     -5.569849e-03 -5.824073e-03 -6.089411e-03 -6.366307e-03
## ASV3600      2.588635e-03  2.707252e-03  2.831096e-03  2.960379e-03
## ASV4013      4.831175e-03  5.048526e-03  5.275078e-03  5.511168e-03
## ASV4136      5.155429e-03  5.381493e-03  5.616608e-03  5.861063e-03
## ASV4195      1.978883e-02  2.066399e-02  2.157478e-02  2.252236e-02
## ASV4407     -7.644653e-03 -7.982670e-03 -8.334442e-03 -8.700421e-03
## ASV4717      1.332211e-03  1.388232e-03  1.446274e-03  1.506382e-03
## ASV6794      3.169821e-03  3.306907e-03  3.449310e-03  3.597186e-03
## ASV8324     -3.922666e-03 -4.096112e-03 -4.276617e-03 -4.464411e-03
## ASV8981     -9.800442e-05 -1.004319e-04 -1.027758e-04 -1.050157e-04
## ASV9859      1.357678e-03  1.425156e-03  1.496100e-03  1.570695e-03
## ASV0936      3.804660e-03  3.980197e-03  4.163564e-03  4.355083e-03
## ASV12683    -4.042982e-06 -4.859652e-06 -5.765430e-06 -6.767965e-06
## ASV1293      2.544714e-03  2.657041e-03  2.773924e-03  2.895514e-03
## ASV13055    -6.062280e-05 -6.190778e-05 -6.311162e-05 -6.421853e-05
## ASV17063    -2.034264e-03 -2.124149e-03 -2.217685e-03 -2.314994e-03
## ASV2228      1.658737e-03  1.732015e-03  1.808268e-03  1.887595e-03
## ASV2769      2.604558e-04  2.740996e-04  2.884961e-04  3.036888e-04
## ASV2803      1.795783e-03  1.872868e-03  1.952882e-03  2.035901e-03
## ASV2896      1.435053e-03  1.501735e-03  1.571448e-03  1.644326e-03
## ASV3062      1.731584e-03  1.815207e-03  1.902904e-03  1.994875e-03
## ASV3107      2.674745e-03  2.798129e-03  2.927029e-03  3.061675e-03
## ASV3265      3.640900e-03  3.801269e-03  3.968109e-03  4.141627e-03
## ASV3666      3.533431e-05  3.666874e-05  3.803318e-05  3.942592e-05
## ASV4497      1.250740e-03  1.306449e-03  1.364464e-03  1.424867e-03
## ASV6914     -1.868825e-04 -1.964834e-04 -2.066020e-04 -2.172675e-04
## ASV0576     -4.346623e-03 -4.531824e-03 -4.723932e-03 -4.923118e-03
## ASV0673      4.817016e-03  5.033026e-03  5.258112e-03  5.492600e-03
## ASV0772      2.235847e-03  2.336797e-03  2.442059e-03  2.551795e-03
## ASV0862      2.150637e-04  2.301194e-04  2.463063e-04  2.637110e-04
## ASV0898      1.736629e-03  1.818535e-03  1.904252e-03  1.993955e-03
## ASV0910      2.004839e-03  2.097768e-03  2.194891e-03  2.296384e-03
## ASV0964     -1.643320e-03 -1.714157e-03 -1.787708e-03 -1.864047e-03
## ASV10059     1.426476e-03  1.494455e-03  1.565668e-03  1.640268e-03
## ASV10263    -3.099336e-03 -3.236438e-03 -3.379125e-03 -3.527582e-03
## ASV1088      3.574840e-03  3.739204e-03  3.910877e-03  4.090165e-03
## ASV1101      4.430883e-03  4.626368e-03  4.829767e-03  5.041339e-03
## ASV1183      1.171697e-03  1.225155e-03  1.280948e-03  1.339167e-03
## ASV11956     1.134305e-03  1.182454e-03  1.232383e-03  1.284136e-03
## ASV12774     6.561738e-05  6.688803e-05  6.805605e-05  6.910315e-05
## ASV1321      5.176126e-03  5.417686e-03  5.670290e-03  5.934421e-03
## ASV13793    -2.136876e-03 -2.231393e-03 -2.329760e-03 -2.432103e-03
## ASV14482     1.361614e-04  1.415891e-04  1.471894e-04  1.529643e-04
## ASV15483     8.791615e-04  9.198202e-04  9.623024e-04  1.006685e-03
## ASV2062      4.097238e-03  4.281197e-03  4.472916e-03  4.672681e-03
## ASV2132      3.345366e-03  3.499675e-03  3.660870e-03  3.829236e-03
## ASV2413      3.167934e-03  3.308481e-03  3.454804e-03  3.607101e-03
## ASV2490      9.752449e-03  1.017651e-02  1.061720e-02  1.107500e-02
## ASV2594      1.219186e-03  1.274914e-03  1.333094e-03  1.393828e-03
## ASV2822     -5.639930e-03 -5.889506e-03 -6.149258e-03 -6.419523e-03
## ASV2863      6.000830e-03  6.264053e-03  6.537820e-03  6.822469e-03
## ASV2910      2.195853e-03  2.292829e-03  2.393744e-03  2.498729e-03
## ASV2980      2.450244e-03  2.560539e-03  2.675510e-03  2.795328e-03
## ASV3307      4.486730e-03  4.685197e-03  4.891748e-03  5.106652e-03
## ASV3474      2.963812e-03  3.103309e-03  3.249285e-03  3.402034e-03
## ASV3502      3.113406e-03  3.255031e-03  3.402799e-03  3.556951e-03
## ASV4236      4.585322e-03  4.783638e-03  4.989614e-03  5.203465e-03
## ASV4842     -4.926871e-04 -5.158547e-04 -5.400772e-04 -5.653977e-04
## ASV4894     -2.137499e-03 -2.232079e-03 -2.330514e-03 -2.432933e-03
## ASV5290      1.697648e-03  1.775715e-03  1.857242e-03  1.942370e-03
## ASV5501      1.038001e-03  1.085211e-03  1.134478e-03  1.185885e-03
## ASV5795      1.140745e-03  1.193343e-03  1.248286e-03  1.305671e-03
## ASV5987     -5.970758e-03 -6.235003e-03 -6.510025e-03 -6.796183e-03
## ASV6267     -6.726999e-03 -7.024653e-03 -7.334442e-03 -7.656769e-03
## ASV6862      2.700891e-03  2.818438e-03  2.940609e-03  3.067543e-03
## ASV7145      1.192683e-03  1.243797e-03  1.296861e-03  1.351929e-03
## ASV7673     -2.137359e-03 -2.231928e-03 -2.330352e-03 -2.432759e-03
## ASV7789      1.058034e-03  1.110215e-03  1.165036e-03  1.222636e-03
## ASV7809      7.152030e-05  7.673160e-05  8.234658e-05  8.839682e-05
## ASV8002     -2.699350e-03 -2.818784e-03 -2.943086e-03 -3.072420e-03
## ASV8205      1.129975e-03  1.181756e-03  1.235820e-03  1.292260e-03
## ASV9155     -6.864946e-04 -7.162971e-04 -7.472603e-04 -7.794175e-04
## ASV9221      2.760088e-04  2.918356e-04  3.086514e-04  3.265228e-04
## ASV9311     -4.329994e-03 -4.521559e-03 -4.720933e-03 -4.928375e-03
## ASV9557     -2.958853e-03 -3.089731e-03 -3.225941e-03 -3.367662e-03
## ASV9936     -5.966177e-03 -6.230025e-03 -6.504619e-03 -6.790314e-03
## ASV1445      3.622866e-03  3.789017e-03  3.962497e-03  4.143602e-03
## ASV4232      1.369566e-03  1.434843e-03  1.503238e-03  1.574900e-03
## ASV6479      4.863533e-04  5.129991e-04  5.412164e-04  5.711045e-04
## ASV0142     -2.572509e-03 -2.685586e-03 -2.803209e-03 -2.925524e-03
## ASV0378      1.166636e-03  1.222259e-03  1.280530e-03  1.341574e-03
## ASV1122      3.505992e-03  3.667732e-03  3.836694e-03  4.013177e-03
## ASV0123     -2.271819e-03 -2.371509e-03 -2.475192e-03 -2.582992e-03
## ASV2064      1.163605e-03  1.212744e-03  1.263664e-03  1.316403e-03
## ASV4459     -1.632167e-04 -1.695427e-04 -1.760476e-04 -1.827306e-04
## ASV0448      9.328596e-04  9.773905e-04  1.024045e-03  1.072923e-03
## ASV0397      2.062344e-03  2.155692e-03  2.253044e-03  2.354554e-03
## ASV0485      2.397672e-03  2.504959e-03  2.616740e-03  2.733176e-03
## ASV1566      3.531156e-03  3.690609e-03  3.856866e-03  4.030182e-03
## ASV1365      3.014607e-03  3.152153e-03  3.295693e-03  3.445463e-03
## ASV1065      4.284557e-03  4.479638e-03  4.683195e-03  4.895559e-03
## ASV0722     -2.234036e-04 -2.339204e-04 -2.449293e-04 -2.564532e-04
## ASV12660    -2.462426e-03 -2.570063e-03 -2.681981e-03 -2.798313e-03
## ASV0223      6.622729e-04  6.920168e-04  7.230186e-04  7.553249e-04
## ASV0229      1.009612e-03  1.056279e-03  1.105039e-03  1.155983e-03
## ASV0877      4.251007e-04  4.428660e-04  4.612454e-04  4.802472e-04
## ASV0983      2.380330e-03  2.486317e-03  2.596688e-03  2.711596e-03
## ASV0626      2.539788e-04  2.689606e-04  2.849000e-04  3.018613e-04
## ASV4146      1.171624e-04  1.223241e-04  1.276817e-04  1.332386e-04
## ASV4175     -2.930454e-03 -3.065320e-03 -3.206177e-03 -3.353271e-03
## ASV2082     -1.313404e-03 -1.380604e-03 -1.451419e-03 -1.526056e-03
## ASV2272      1.395638e-03  1.459572e-03  1.526327e-03  1.596016e-03
## ASV2245     -2.092491e-03 -2.189264e-03 -2.290376e-03 -2.396010e-03
## ASV0590     -1.236933e-03 -1.302184e-03 -1.371095e-03 -1.443886e-03
## ASV0217      1.049717e-04  1.146809e-04  1.252594e-04  1.367811e-04
## ASV0416      1.595144e-03  1.661816e-03  1.730842e-03  1.802266e-03
## ASV1056      2.022441e-03  2.117190e-03  2.216297e-03  2.319954e-03
## ASV7777     -2.852719e-03 -2.983343e-03 -3.119717e-03 -3.262075e-03
## ASV0455      5.121197e-04  5.354016e-04  5.596907e-04  5.850260e-04
## ASV0604      1.330847e-03  1.393884e-03  1.459881e-03  1.528973e-03
## ASV6100     -1.964821e-03 -2.055812e-03 -2.150902e-03 -2.250268e-03
## ASV11359    -4.225563e-03 -4.419099e-03 -4.621145e-03 -4.832041e-03
## ASV6604      5.853588e-04  6.129648e-04  6.418570e-04  6.720937e-04
## ASV5004     -1.503387e-03 -1.571768e-03 -1.643117e-03 -1.717551e-03
## ASV1483     -6.477295e-04 -6.770102e-04 -7.075435e-04 -7.393765e-04
## ASV9773     -1.903098e-03 -1.990689e-03 -2.082175e-03 -2.177718e-03
## ASV4059      1.230152e-06  5.014133e-06  9.303857e-06  1.414994e-05
## ASV1193      2.300666e-03  2.404931e-03  2.513681e-03  2.627087e-03
## ASV4610     -3.661226e-04 -3.775800e-04 -3.890797e-04 -4.005850e-04
## ASV0742     -2.213673e-04 -2.271353e-04 -2.327659e-04 -2.382197e-04
## ASV1502     -1.018040e-04 -1.091319e-04 -1.170235e-04 -1.255230e-04
## ASV0195      5.676955e-05  5.769748e-05  5.851858e-05  5.921598e-05
## ASV1213      1.623969e-03  1.693413e-03  1.765467e-03  1.840201e-03
## ASV1648     -1.764765e-03 -1.846350e-03 -1.931601e-03 -2.020674e-03
## ASV6984     -1.651099e-03 -1.727503e-03 -1.807348e-03 -1.890782e-03
## ASV0396     -9.473409e-05 -9.720062e-05 -9.961228e-05 -1.019534e-04
## ASV4297      2.354384e-03  2.456789e-03  2.563205e-03  2.673751e-03
## ASV2622      3.649998e-03  3.811812e-03  3.980261e-03  4.155568e-03
## ASV3512      1.416841e-03  1.486775e-03  1.560256e-03  1.637471e-03
## ASV2411      2.483096e-03  2.599751e-03  2.721808e-03  2.849509e-03
## ASV2291     -1.068527e-03 -1.125776e-03 -1.186300e-03 -1.250300e-03
## ASV0807      3.388469e-03  3.542115e-03  3.702374e-03  3.869500e-03
## ASV1292      8.199389e-04  8.542125e-04  8.897006e-04  9.264268e-04
## ASV1035      3.109868e-03  3.246542e-03  3.388724e-03  3.536593e-03
## ASV0070      2.592338e-05  2.888531e-05  3.214154e-05  3.571889e-05
## ASV0255      2.949844e-04  3.073748e-04  3.202046e-04  3.334815e-04
## ASV0057     -8.561783e-04 -8.928395e-04 -9.308809e-04 -9.703377e-04
## ASV0077     -1.819354e-04 -1.890515e-04 -1.963698e-04 -2.038887e-04
## ASV0625      1.791010e-03  1.869123e-03  1.950318e-03  2.034689e-03
## ASV2464      1.218761e-02  1.271684e-02  1.326681e-02  1.383816e-02
## ASV1315      3.234892e-03  3.387562e-03  3.547362e-03  3.714616e-03
## ASV2673      2.774736e-03  2.905870e-03  3.043145e-03  3.186841e-03
## ASV2161      1.173485e-03  1.228775e-03  1.286642e-03  1.347205e-03
## ASV0337     -6.720828e-04 -7.030914e-04 -7.354841e-04 -7.693186e-04
## ASV7680     -4.386083e-03 -4.589037e-03 -4.801111e-03 -5.022689e-03
## ASV0611      2.449623e-03  2.563140e-03  2.681776e-03  2.805751e-03
## ASV3118     -2.542923e-03 -2.663670e-03 -2.790119e-03 -2.922534e-03
## ASV1284      9.107706e-04  9.404108e-04  9.702509e-04  1.000200e-03
## ASV0889      1.853281e-03  1.935939e-03  2.022038e-03  2.111700e-03
## ASV4649     -9.284650e-04 -9.708583e-04 -1.015106e-03 -1.061282e-03
## ASV1108     -1.902387e-03 -1.993857e-03 -2.089753e-03 -2.190291e-03
## ASV0738      1.050799e-03  1.103971e-03  1.159949e-03  1.218887e-03
## ASV0473     -2.133049e-04 -2.251642e-04 -2.377266e-04 -2.510353e-04
## ASV0598     -5.367863e-04 -5.649136e-04 -5.946089e-04 -6.259659e-04
## ASV0429      1.375479e-03  1.435909e-03  1.498757e-03  1.564101e-03
## ASV1549      2.560198e-03  2.681362e-03  2.808215e-03  2.941019e-03
## ASV1203      2.015487e-03  2.105729e-03  2.199752e-03  2.297689e-03
## ASV4532      8.663477e-05  8.971311e-05  9.285198e-05  9.604802e-05
## ASV0274      3.513964e-04  3.686822e-04  3.868328e-04  4.058918e-04
## ASV0163     -1.556086e-03 -1.623698e-03 -1.693959e-03 -1.766948e-03
## ASV1298      1.700955e-04  1.767247e-04  1.835503e-04  1.905732e-04
## ASV9424     -3.400319e-03 -3.558390e-03 -3.723639e-03 -3.896377e-03
## ASV0412      3.496440e-03  3.652044e-03  3.814086e-03  3.982793e-03
## ASV0284      7.302303e-04  7.600051e-04  7.907577e-04  8.224980e-04
## ASV0620     -7.187704e-04 -7.551711e-04 -7.934906e-04 -8.338347e-04
## ASV0153     -3.422881e-03 -3.584823e-03 -3.754359e-03 -3.931839e-03
## ASV0498      1.207259e-03  1.263186e-03  1.321623e-03  1.382676e-03
## ASV0097      6.724150e-04  7.042155e-04  7.375081e-04  7.723616e-04
## ASV0104     -4.748483e-03 -4.962832e-03 -5.186316e-03 -5.419277e-03
## ASV1282      1.636553e-03  1.708147e-03  1.782576e-03  1.859923e-03
## ASV3883     -1.305135e-03 -1.368971e-03 -1.435980e-03 -1.506323e-03
## ASV0801      6.438717e-04  6.736594e-04  7.047831e-04  7.372987e-04
## ASV1611     -3.048963e-03 -3.191937e-03 -3.341508e-03 -3.497972e-03
## ASV0227     -5.520301e-04 -5.809091e-04 -6.113831e-04 -6.435449e-04
## ASV0833      1.036325e-03  1.084078e-03  1.133955e-03  1.186043e-03
## ASV0718      4.635785e-03  4.848520e-03  5.070658e-03  5.302583e-03
## ASV1139      5.952772e-04  6.178501e-04  6.409846e-04  6.646645e-04
## ASV0766     -6.490422e-04 -6.808834e-04 -7.143135e-04 -7.494127e-04
## ASV2091      3.761302e-03  3.925523e-03  4.096236e-03  4.273637e-03
## ASV1238     -3.448634e-03 -3.609241e-03 -3.777178e-03 -3.952768e-03
## ASV9193     -3.330625e-04 -3.523705e-04 -3.729059e-04 -3.947531e-04
## ASV0290      4.897049e-04  5.092820e-04  5.294687e-04  5.502684e-04
## ASV0231      1.376350e-03  1.437585e-03  1.501350e-03  1.567731e-03
## ASV0185      8.061799e-04  8.468161e-04  8.895834e-04  9.345992e-04
## ASV2330      1.575969e-03  1.643765e-03  1.714147e-03  1.787184e-03
## ASV3119     -7.298725e-04 -7.664407e-04 -8.049062e-04 -8.453717e-04
## ASV2368     -1.771070e-03 -1.855071e-03 -1.943043e-03 -2.035174e-03
## ASV0122     -8.556685e-04 -8.940832e-04 -9.341179e-04 -9.758318e-04
## ASV1044      2.196792e-03  2.299846e-03  2.407659e-03  2.520446e-03
## ASV0160     -9.174855e-04 -9.570404e-04 -9.981133e-04 -1.040746e-03
## ASV0326      2.430200e-04  2.542429e-04  2.659655e-04  2.782082e-04
## ASV1388      4.439370e-03  4.639387e-03  4.847895e-03  5.065207e-03
## ASV0792      3.292049e-03  3.437293e-03  3.588422e-03  3.745630e-03
## ASV0036     -1.026813e-03 -1.075428e-03 -1.126324e-03 -1.179605e-03
## ASV2125      3.174060e-03  3.317900e-03  3.467924e-03  3.624368e-03
## ASV1075     -4.776934e-05 -4.993771e-05 -5.220281e-05 -5.456911e-05
## ASV0390      1.695665e-03  1.775912e-03  1.859933e-03  1.947903e-03
## ASV3790     -2.406315e-03 -2.517544e-03 -2.633762e-03 -2.755179e-03
## ASV1535     -6.954451e-04 -7.300413e-04 -7.664118e-04 -8.046509e-04
## ASV0263      2.946154e-03  3.080716e-03  3.221163e-03  3.367731e-03
## ASV0675      4.429515e-03  4.635918e-03  4.851729e-03  5.077356e-03
## ASV3348      3.594622e-04  3.769822e-04  3.953684e-04  4.146644e-04
## ASV0058     -1.312918e-03 -1.371905e-03 -1.433382e-03 -1.497438e-03
## ASV4142      1.840818e-03  1.921820e-03  2.006076e-03  2.093687e-03
## ASV0059     -1.057456e-03 -1.104668e-03 -1.153845e-03 -1.205055e-03
## ASV0013     -1.880792e-03 -1.966543e-03 -2.056031e-03 -2.149401e-03
## ASV0033     -8.924966e-04 -9.346202e-04 -9.787093e-04 -1.024853e-03
## ASV4354     -1.107946e-03 -1.158544e-03 -1.211365e-03 -1.266498e-03
## ASV0022     -7.536621e-04 -7.892005e-04 -8.263950e-04 -8.653206e-04
## ASV0134     -7.173350e-04 -7.521585e-04 -7.886947e-04 -8.270288e-04
## ASV0415      1.155812e-04  1.218410e-04  1.284587e-04  1.354552e-04
## ASV10103    -4.185376e-03 -4.380488e-03 -4.584500e-03 -4.797799e-03
## ASV1613      3.121078e-03  3.258914e-03  3.402342e-03  3.551542e-03
## ASV0135     -4.009819e-04 -4.181246e-04 -4.359094e-04 -4.543521e-04
## ASV0469     -4.029279e-03 -4.209436e-03 -4.397128e-03 -4.592627e-03
## ASV0471      2.452807e-03  2.564361e-03  2.680749e-03  2.802160e-03
## ASV0451     -4.020577e-04 -4.236393e-04 -4.464585e-04 -4.705908e-04
## ASV0747      1.395997e-03  1.460235e-03  1.527325e-03  1.597381e-03
## ASV1314     -1.402457e-03 -1.469093e-03 -1.538887e-03 -1.611988e-03
## ASV0425     -4.987330e-03 -5.206239e-03 -5.433915e-03 -5.670634e-03
## ASV0559     -1.233957e-03 -1.289816e-03 -1.348085e-03 -1.408859e-03
## ASV0148     -2.791562e-04 -2.896555e-04 -3.004051e-04 -3.113957e-04
## ASV0129      2.888646e-04  3.062468e-04  3.247790e-04  3.445430e-04
## ASV1072      3.308637e-04  3.444894e-04  3.585719e-04  3.731163e-04
## ASV2390      2.555190e-03  2.665381e-03  2.779787e-03  2.898521e-03
## ASV0548      1.687770e-03  1.764319e-03  1.844165e-03  1.927435e-03
## ASV0168     -8.664047e-04 -9.050698e-04 -9.453438e-04 -9.872835e-04
## ASV0066     -9.761051e-04 -1.019987e-03 -1.065722e-03 -1.113376e-03
## ASV0468     -5.170392e-04 -5.407197e-04 -5.654435e-04 -5.912528e-04
## ASV0172     -2.924301e-04 -3.043947e-04 -3.167539e-04 -3.295115e-04
## ASV0236     -5.433021e-05 -5.140058e-05 -4.784595e-05 -4.359654e-05
## ASV0250      1.377144e-03  1.444731e-03  1.515712e-03  1.590261e-03
## ASV0338      6.532307e-04  6.841498e-04  7.165114e-04  7.503798e-04
## ASV0450     -1.223026e-04 -1.290828e-04 -1.362689e-04 -1.438868e-04
## ASV0377      1.219411e-03  1.274082e-03  1.331050e-03  1.390397e-03
## ASV1022     -5.184097e-05 -5.397604e-05 -5.617894e-05 -5.844943e-05
## ASV6174     -2.674879e-05 -2.854469e-05 -3.047683e-05 -3.255650e-05
## ASV0786     -1.701411e-04 -1.801677e-04 -1.908327e-04 -2.021785e-04
## ASV0053     -1.319331e-03 -1.379748e-03 -1.442820e-03 -1.508655e-03
## ASV0697     -8.023062e-04 -8.377183e-04 -8.745700e-04 -9.129092e-04
## ASV0785      1.689154e-03  1.764937e-03  1.843910e-03  1.926186e-03
## ASV1967     -1.678323e-03 -1.753054e-03 -1.830889e-03 -1.911938e-03
## ASV0385      5.650852e-04  5.920920e-04  6.203851e-04  6.500246e-04
## ASV0295      1.001961e-04  1.064390e-04  1.131096e-04  1.202393e-04
## ASV0072     -1.312471e-03 -1.370621e-03 -1.431146e-03 -1.494126e-03
## ASV0157     -1.671307e-04 -1.722417e-04 -1.773408e-04 -1.824056e-04
## ASV0501      2.848775e-03  2.979634e-03  3.116282e-03  3.258954e-03
## ASV10729    -3.580508e-03 -3.745998e-03 -3.918906e-03 -4.099545e-03
## ASV1470      1.824598e-03  1.902825e-03  1.984006e-03  2.068217e-03
## ASV0050     -3.089741e-03 -3.228720e-03 -3.373578e-03 -3.524529e-03
## ASV0411     -6.975267e-04 -7.303287e-04 -7.646522e-04 -8.005656e-04
## ASV0549      1.121168e-03  1.173364e-03  1.227934e-03  1.284980e-03
## ASV0184      3.747267e-04  3.916012e-04  4.091954e-04  4.275368e-04
## ASV0705      7.410482e-04  7.738746e-04  8.080407e-04  8.435907e-04
## ASV1715      1.567921e-03  1.639616e-03  1.714454e-03  1.792559e-03
## ASV0603      2.443942e-04  2.558850e-04  2.679135e-04  2.805048e-04
## ASV0826      2.647066e-03  2.766745e-03  2.891546e-03  3.021666e-03
## ASV0034     -8.477887e-04 -8.854508e-04 -9.246618e-04 -9.654741e-04
## ASV0838      5.841981e-04  6.049806e-04  6.261154e-04  6.475640e-04
## ASV0614     -7.247566e-04 -7.574693e-04 -7.915787e-04 -8.271375e-04
## ASV0014     -1.920725e-03 -2.007850e-03 -2.098729e-03 -2.193506e-03
## ASV0585      2.126767e-04  2.178856e-04  2.229106e-04  2.277075e-04
## ASV0016     -2.006469e-03 -2.097480e-03 -2.192413e-03 -2.291417e-03
## ASV5394     -1.504330e-03 -1.573454e-03 -1.645638e-03 -1.721008e-03
## ASV0666      3.281727e-03  3.426305e-03  3.576726e-03  3.733177e-03
## ASV2085      7.559391e-04  7.828470e-04  8.102404e-04  8.380769e-04
## ASV0003     -1.368194e-03 -1.430197e-03 -1.494867e-03 -1.562305e-03
## ASV0346      6.877613e-04  7.204474e-04  7.546756e-04  7.905165e-04
## ASV0267     -5.803061e-06 -4.587939e-06 -3.182777e-06 -1.567622e-06
## ASV0353      1.093419e-03  1.144651e-03  1.198244e-03  1.254301e-03
## ASV2419      2.945373e-03  3.077798e-03  3.215825e-03  3.359659e-03
## ASV0447      1.603073e-03  1.678420e-03  1.757255e-03  1.839733e-03
## ASV0654      2.375757e-03  2.483714e-03  2.596338e-03  2.713811e-03
## ASV0151      3.167857e-04  3.329556e-04  3.499918e-04  3.679435e-04
## ASV0065     -9.194757e-04 -9.608490e-04 -1.003975e-03 -1.048917e-03
## ASV0527      2.260791e-03  2.363059e-03  2.469708e-03  2.580907e-03
## ASV4055     -3.573135e-04 -3.748230e-04 -3.932146e-04 -4.125351e-04
## ASV0166     -1.136001e-03 -1.186044e-03 -1.238107e-03 -1.292255e-03
## ASV0417     -4.649522e-04 -4.845614e-04 -5.048797e-04 -5.259221e-04
## ASV0078     -6.730939e-04 -7.029654e-04 -7.340610e-04 -7.664219e-04
## ASV0322     -1.233711e-04 -1.275617e-04 -1.317905e-04 -1.360441e-04
## ASV0156     -1.600837e-03 -1.674827e-03 -1.752138e-03 -1.832910e-03
## ASV0648     -3.475943e-03 -3.637386e-03 -3.806138e-03 -3.982513e-03
## ASV0407     -2.605536e-04 -2.729694e-04 -2.859770e-04 -2.996046e-04
## ASV2030     -5.793770e-04 -6.052084e-04 -6.321331e-04 -6.601942e-04
## ASV0300      4.148019e-04  4.345176e-04  4.551655e-04  4.767890e-04
## ASV1150      9.313087e-05  9.796747e-05  1.030678e-04  1.084469e-04
## ASV0958      1.281663e-03  1.342730e-03  1.406706e-03  1.473728e-03
## ASV0216     -1.419393e-03 -1.482881e-03 -1.549035e-03 -1.617952e-03
## ASV0446      2.142042e-03  2.241557e-03  2.345573e-03  2.454285e-03
## ASV0367     -1.403641e-03 -1.468107e-03 -1.535426e-03 -1.605715e-03
## ASV0200     -8.349739e-04 -8.732626e-04 -9.132393e-04 -9.549723e-04
## ASV0334     -4.535170e-04 -4.715699e-04 -4.901764e-04 -5.093383e-04
## ASV1311      5.488682e-04  5.717173e-04  5.953618e-04  6.198149e-04
## ASV0458      8.113225e-04  8.446291e-04  8.790578e-04  9.146241e-04
## ASV1371      1.314925e-04  1.380199e-04  1.448778e-04  1.520828e-04
## ASV0418      1.861076e-03  1.942631e-03  2.027442e-03  2.115612e-03
## ASV0004      2.698145e-04  2.815676e-04  2.937831e-04  3.064749e-04
## ASV1943      5.171555e-03  5.380755e-03  5.596790e-03  5.819745e-03
## ASV1495     -3.722364e-04 -3.933923e-04 -4.158577e-04 -4.397202e-04
## ASV0901     -1.576460e-03 -1.650175e-03 -1.727278e-03 -1.807918e-03
## ASV0628      8.383269e-04  8.741104e-04  9.112276e-04  9.497104e-04
## ASV0400      5.098547e-04  5.323839e-04  5.558262e-04  5.802109e-04
## ASV0116     -4.635945e-04 -4.852218e-04 -5.078377e-04 -5.314856e-04
## ASV0788      4.097782e-03  4.289439e-03  4.489901e-03  4.699560e-03
## ASV0117      3.019078e-04  3.164463e-04  3.316894e-04  3.476713e-04
## ASV3137     -9.593570e-05 -1.001817e-04 -1.046009e-04 -1.091991e-04
## ASV0001      2.897150e-04  3.022612e-04  3.152938e-04  3.288265e-04
## ASV1651      8.254526e-04  8.615604e-04  8.991031e-04  9.381252e-04
## ASV1692      3.412750e-03  3.572067e-03  3.738673e-03  3.912887e-03
## ASV0660      1.218345e-03  1.269748e-03  1.323005e-03  1.378153e-03
## ASV0508      6.112486e-05  6.362945e-05  6.621830e-05  6.889261e-05
## ASV1660     -6.876102e-04 -7.215438e-04 -7.571874e-04 -7.946284e-04
## ASV0233      1.054079e-03  1.102364e-03  1.152776e-03  1.205399e-03
## ASV1343     -1.943594e-03 -2.034047e-03 -2.128614e-03 -2.227475e-03
## ASV0209      9.689220e-04  1.010975e-03  1.054666e-03  1.100044e-03
## ASV0193     -1.131175e-03 -1.180639e-03 -1.232066e-03 -1.285513e-03
## ASV0357      4.340107e-04  4.561251e-04  4.794237e-04  5.039745e-04
## ASV0198      8.589353e-04  8.974031e-04  9.374850e-04  9.792394e-04
## ASV0007      2.557832e-04  2.666859e-04  2.779946e-04  2.897192e-04
## ASV1772     -3.804987e-04 -3.963012e-04 -4.126385e-04 -4.295162e-04
## ASV0009      2.113460e-04  2.201984e-04  2.293653e-04  2.388529e-04
## ASV0006     -2.311664e-04 -2.422401e-04 -2.538456e-04 -2.660086e-04
## ASV0011     -8.015753e-04 -8.387127e-04 -8.775229e-04 -9.180769e-04
## ASV0015      1.597347e-04  1.664195e-04  1.733408e-04  1.805031e-04
## ASV0017      1.799551e-04  1.874976e-04  1.953088e-04  2.033938e-04
## ASV0235     -7.406419e-04 -7.751598e-04 -8.112495e-04 -8.489789e-04
## ASV0382      5.797507e-04  6.067598e-04  6.349910e-04  6.644953e-04
## ASV2357      2.414774e-03  2.526500e-03  2.643249e-03  2.765233e-03
## ASV0567     -4.677749e-04 -4.896116e-04 -5.124521e-04 -5.363419e-04
## ASV0165      4.028855e-04  4.215216e-04  4.409934e-04  4.613360e-04
## ASV0005      5.844966e-04  6.109866e-04  6.386148e-04  6.674248e-04
## ASV0384     -6.352907e-05 -6.513997e-05 -6.670086e-05 -6.819857e-05
## ASV0002      1.093635e-04  1.141705e-04  1.191713e-04  1.243725e-04
## ASV3017      3.095586e-03  3.231200e-03  3.372216e-03  3.518801e-03
## ASV0091     -7.846886e-05 -8.196510e-05 -8.560817e-05 -8.940363e-05
## ASV0186     -1.178153e-03 -1.231844e-03 -1.287869e-03 -1.346320e-03
## ASV0370      6.248481e-04  6.528151e-04  6.819509e-04  7.122970e-04
## ASV0018      7.487874e-04  7.828274e-04  8.183402e-04  8.553826e-04
## ASV1377      7.507272e-03  7.838942e-03  8.184094e-03  8.543174e-03
## ASV0019      7.855467e-04  8.212906e-04  8.585840e-04  8.974874e-04
## ASV0023     -4.911193e-04 -5.140591e-04 -5.380483e-04 -5.631331e-04
## ASV2194      7.894751e-04  8.267565e-04  8.657851e-04  9.066416e-04
## ASV1155      3.140859e-03  3.279223e-03  3.423215e-03  3.573026e-03
## ASV0510     -8.417917e-04 -8.771735e-04 -9.138199e-04 -9.517559e-04
## ASV2371     -1.891384e-03 -1.974761e-03 -2.061525e-03 -2.151792e-03
## ASV0024     -6.115416e-04 -6.400209e-04 -6.697956e-04 -7.009218e-04
## ASV2452      1.900078e-03  1.981325e-03  2.065614e-03  2.153022e-03
## ASV2332     -5.431543e-03 -5.673118e-03 -5.924710e-03 -6.186674e-03
## ASV2591      1.422144e-03  1.493767e-03  1.569088e-03  1.648300e-03
## ASV0521      1.242481e-03  1.300270e-03  1.360682e-03  1.423832e-03
## ASV5542      1.189413e-03  1.244799e-03  1.302691e-03  1.363194e-03
## ASV0336     -1.498512e-04 -1.582792e-04 -1.672179e-04 -1.767002e-04
## ASV10102     2.197535e-03  2.299648e-03  2.406380e-03  2.517928e-03
## ASV16823    -3.393273e-03 -3.539420e-03 -3.691197e-03 -3.848766e-03
## ASV3104      1.755432e-02  1.831024e-02  1.909526e-02  1.991023e-02
## ASV0781      2.450927e-03  2.562142e-03  2.678154e-03  2.799147e-03
## ASV10899     1.438617e-03  1.511405e-03  1.588015e-03  1.668656e-03
## ASV11222    -5.970948e-03 -6.228045e-03 -6.495041e-03 -6.772221e-03
## ASV11327    -5.359878e-03 -5.590620e-03 -5.830243e-03 -6.079001e-03
## ASV12458    -5.968768e-03 -6.225674e-03 -6.492464e-03 -6.769421e-03
## ASV1636      3.372321e-03  3.522168e-03  3.678183e-03  3.840576e-03
## ASV1890     -2.745431e-03 -2.859327e-03 -2.977220e-03 -3.099189e-03
## ASV2898      4.521664e-03  4.722771e-03  4.932181e-03  5.150180e-03
## ASV8328      5.308833e-04  5.668742e-04  6.054906e-04  6.469290e-04
## ASV0709     -5.040518e-03 -5.267731e-03 -5.504586e-03 -5.751439e-03
## ASV0856      4.183806e-03  4.381404e-03  4.588228e-03  4.804697e-03
## ASV0909      1.204769e-03  1.268951e-03  1.336777e-03  1.408466e-03
## ASV0937     -2.962200e-03 -3.099537e-03 -3.243094e-03 -3.393140e-03
## ASV11390    -8.517453e-03 -8.884010e-03 -9.264664e-03 -9.659822e-03
## ASV11966     2.048157e-03  2.146902e-03  2.250423e-03  2.358950e-03
## ASV12990     1.486616e-03  1.552234e-03  1.620500e-03  1.691498e-03
## ASV14797     2.202576e-03  2.298760e-03  2.398748e-03  2.502658e-03
## ASV14904    -1.222180e-02 -1.274776e-02 -1.329395e-02 -1.386094e-02
## ASV15304     1.282114e-03  1.346142e-03  1.413449e-03  1.484207e-03
## ASV16696    -4.222298e-03 -4.403980e-03 -4.592647e-03 -4.788500e-03
## ASV1690      7.109131e-03  7.445843e-03  7.798307e-03  8.167232e-03
## ASV2029      4.955563e-03  5.178044e-03  5.409912e-03  5.651510e-03
## ASV2834      6.206399e-03  6.492548e-03  6.791451e-03  7.103636e-03
## ASV4003      5.094110e-03  5.339976e-03  5.597817e-03  5.868221e-03
## ASV4064      2.944586e-03  3.081313e-03  3.224213e-03  3.373547e-03
## ASV4294      1.774710e-03  1.863234e-03  1.956306e-03  2.054167e-03
## ASV4609      1.676335e-03  1.751303e-03  1.829396e-03  1.910724e-03
## ASV6283     -3.947318e-03 -4.117194e-03 -4.293604e-03 -4.476738e-03
## ASV6491     -5.656702e-03 -5.900096e-03 -6.152850e-03 -6.415232e-03
## ASV7453      2.715710e-03  2.847331e-03  2.985378e-03  3.130162e-03
## ASV7959      9.724051e-04  1.023910e-03  1.078297e-03  1.135737e-03
## ASV8219      4.888174e-02  5.098486e-02  5.316885e-02  5.543602e-02
## ASV8547     -5.063099e-03 -5.280896e-03 -5.507065e-03 -5.741843e-03
## ASV9319      2.194611e-03  2.297924e-03  2.406033e-03  2.519151e-03
## ASV9382     -9.905600e-03 -1.033166e-02 -1.077410e-02 -1.123338e-02
## ASV11516    -6.614941e-03 -6.899412e-03 -7.194811e-03 -7.501449e-03
## ASV14377    -4.775474e-03 -4.980802e-03 -5.194013e-03 -5.415333e-03
## ASV1867      3.684093e-03  3.855102e-03  4.033838e-03  4.220631e-03
## ASV1895      1.858228e-03  1.937767e-03  2.020276e-03  2.105826e-03
## ASV3168      2.336802e-03  2.438880e-03  2.544979e-03  2.655220e-03
## ASV4449      1.284883e-02  1.343074e-02  1.403774e-02  1.467081e-02
## ASV6596      2.663564e-03  2.793769e-03  2.930454e-03  3.073950e-03
## ASV7492     -4.962234e-04 -5.098174e-04 -5.232100e-04 -5.363261e-04
## ASV9854     -1.022010e-03 -1.065251e-03 -1.110099e-03 -1.156597e-03
## ASV6296      8.011740e-02  8.356140e-02  8.713759e-02  9.084972e-02
## ASV4201      3.755662e-04  4.020127e-04  4.304477e-04  4.610232e-04
## ASV0552      2.549790e-03  2.667670e-03  2.790834e-03  2.919503e-03
## ASV3671     -1.702007e-03 -1.778205e-03 -1.857631e-03 -1.940408e-03
## ASV3529     -4.505069e-04 -4.637365e-04 -4.769174e-04 -4.899972e-04
## ASV1060      6.773426e-04  7.095134e-04  7.432101e-04  7.785050e-04
## ASV0239     -9.208525e-04 -9.600277e-04 -1.000658e-03 -1.042778e-03
## ASV5711     -4.161696e-03 -4.346788e-03 -4.539560e-03 -4.740287e-03
## ASV4152     -5.878250e-03 -6.146824e-03 -6.427175e-03 -6.719779e-03
## ASV1461      2.970590e-03  3.097920e-03  3.230060e-03  3.367135e-03
## ASV2877      1.542030e-03  1.608872e-03  1.678307e-03  1.750405e-03
## ASV0012      2.656486e-04  2.777438e-04  2.903652e-04  3.035335e-04
## ASV9823      3.804821e-04  3.948594e-04  4.095823e-04  4.246376e-04
## ASV0008      2.834547e-04  2.962810e-04  3.096582e-04  3.236077e-04
## ASV7832     -3.459819e-03 -3.618648e-03 -3.784531e-03 -3.957764e-03
## ASV1915     -4.399342e-04 -4.591330e-04 -4.791086e-04 -4.998888e-04
## ASV0055     -3.044679e-04 -3.196516e-04 -3.356167e-04 -3.524049e-04
## ASV0032      1.422424e-04  1.478904e-04  1.537095e-04  1.596997e-04
## ASV2977     -4.877933e-03 -5.100019e-03 -5.331772e-03 -5.573573e-03
## ASV0466      3.930341e-03  4.098969e-03  4.273991e-03  4.455575e-03
## ASV3866      2.676863e-03  2.801845e-03  2.932546e-03  3.069216e-03
## ASV0040      9.676739e-04  1.012157e-03  1.058614e-03  1.107124e-03
## ASV0496     -2.257369e-04 -2.403338e-04 -2.559595e-04 -2.726898e-04
## ASV0052      8.123755e-04  8.497711e-04  8.888289e-04  9.296175e-04
## ASV3828     -2.838105e-03 -2.959756e-03 -3.086043e-03 -3.217095e-03
## ASV1930      1.453640e-03  1.517801e-03  1.584555e-03  1.653982e-03
## ASV2126      2.475998e-03  2.587246e-03  2.703193e-03  2.824013e-03
## ASV0793      3.033004e-03  3.174045e-03  3.321484e-03  3.475596e-03
## ASV0299     -5.947131e-05 -6.236647e-05 -6.541469e-05 -6.862591e-05
## ASV0208      2.191243e-03  2.291923e-03  2.397066e-03  2.506854e-03
## ASV0511     -9.048086e-04 -9.431716e-04 -9.829395e-04 -1.024144e-03
## ASV1123     -2.736802e-03 -2.853840e-03 -2.975289e-03 -3.101263e-03
## ASV0099      8.142474e-05  8.566844e-05  9.014950e-05  9.488257e-05
## ASV0752     -1.557461e-03 -1.631456e-03 -1.708945e-03 -1.790089e-03
## ASV0883      2.136775e-03  2.237879e-03  2.343719e-03  2.454512e-03
## ASV0683      2.794702e-03  2.925694e-03  3.062720e-03  3.206046e-03
## ASV4117     -4.456959e-03 -4.661533e-03 -4.875176e-03 -5.098264e-03
## ASV2172      2.912579e-04  3.026958e-04  3.144598e-04  3.265468e-04
## ASV0330     -8.323892e-04 -8.709359e-04 -9.112183e-04 -9.533102e-04
## ASV0728      4.116037e-03  4.303187e-03  4.498431e-03  4.702081e-03
## ASV0499      1.087368e-03  1.138514e-03  1.192033e-03  1.248034e-03
## ASV0120     -1.825399e-03 -1.908573e-03 -1.995361e-03 -2.085904e-03
## ASV1446      1.409531e-03  1.466000e-03  1.524237e-03  1.584252e-03
## ASV17171    -3.527148e-03 -3.687223e-03 -3.854238e-03 -4.028468e-03
## ASV0533      2.616323e-04  2.744451e-04  2.878971e-04  3.020208e-04
## ASV2495     -8.590410e-04 -9.024263e-04 -9.481083e-04 -9.962168e-04
## ASV5582      1.638086e-03  1.705792e-03  1.775817e-03  1.848198e-03
## ASV1488      6.239379e-04  6.513582e-04  6.798745e-04  7.095203e-04
## ASV0682      7.920017e-04  8.294587e-04  8.686714e-04  9.097200e-04
## ASV0068     -1.382137e-03 -1.445396e-03 -1.511430e-03 -1.580349e-03
## ASV1987     -3.433417e-03 -3.597042e-03 -3.768439e-03 -3.947970e-03
## ASV0035     -2.522851e-04 -2.665336e-04 -2.816633e-04 -2.977338e-04
## ASV7192     -2.143489e-03 -2.239022e-03 -2.338528e-03 -2.442147e-03
## ASV0873     -1.870827e-04 -2.458476e-04 -3.115292e-04 -3.847616e-04
## ASV4749     -5.971104e-05 -7.101605e-05 -8.360092e-05 -9.758731e-05
## ASV2174      1.495144e-03  1.557747e-03  1.622569e-03  1.689654e-03
## ASV1476     -1.523082e-03 -1.594929e-03 -1.670143e-03 -1.748880e-03
## ASV0740     -4.325039e-03 -4.528665e-03 -4.741761e-03 -4.964756e-03
## ASV0170     -8.477544e-04 -8.865996e-04 -9.271559e-04 -9.694927e-04
## ASV2466     -3.865049e-03 -4.042204e-03 -4.227186e-03 -4.420316e-03
## ASV1709      1.420560e-03  1.483019e-03  1.548029e-03  1.615681e-03
## ASV6170     -6.046157e-03 -6.327896e-03 -6.622479e-03 -6.930464e-03
## ASV3673      2.967512e-03  3.107172e-03  3.253323e-03  3.406256e-03
## ASV1745     -7.669276e-04 -8.043309e-04 -8.435889e-04 -8.847952e-04
##                                                                    
## (Intercept)  2.462850e-02  2.574882e-02  2.691760e-02  2.813667e-02
## ASV1236      4.847701e-03  5.059458e-03  5.279637e-03  5.508503e-03
## ASV0421      5.660116e-04  5.967619e-04  6.292917e-04  6.637090e-04
## ASV0691     -3.747908e-03 -3.899686e-03 -4.056420e-03 -4.218167e-03
## ASV0899      4.203199e-03  4.387748e-03  4.579680e-03  4.779225e-03
## ASV1004      9.709299e-03  1.013494e-02  1.057760e-02  1.103782e-02
## ASV1041     -3.990819e-03 -4.164702e-03 -4.345402e-03 -4.533117e-03
## ASV1058      6.058952e-03  6.324079e-03  6.599776e-03  6.886379e-03
## ASV12542     2.344361e-03  2.444578e-03  2.548579e-03  2.656465e-03
## ASV1294      5.639597e-03  5.886766e-03  6.143825e-03  6.411090e-03
## ASV13113     1.901313e-03  1.992327e-03  2.087709e-03  2.187668e-03
## ASV1318      5.623123e-03  5.869328e-03  6.125354e-03  6.391512e-03
## ASV2269     -9.733512e-03 -1.015817e-02 -1.059959e-02 -1.105830e-02
## ASV2542      4.771179e-03  4.991843e-03  5.222421e-03  5.463335e-03
## ASV2660     -3.871233e-03 -4.039155e-03 -4.213627e-03 -4.394841e-03
## ASV2737      1.334885e-03  1.390345e-03  1.447758e-03  1.507164e-03
## ASV2840      5.149127e-03  5.366951e-03  5.592746e-03  5.826693e-03
## ASV3053      2.638971e-02  2.752091e-02  2.869509e-02  2.991343e-02
## ASV3077      1.683837e-03  1.756335e-03  1.831623e-03  1.909780e-03
## ASV3134      3.030468e-03  3.173352e-03  3.322905e-03  3.479430e-03
## ASV3140      4.092479e-03  4.278283e-03  4.472108e-03  4.674262e-03
## ASV3579      1.463004e-03  1.534997e-03  1.610608e-03  1.690024e-03
## ASV6119     -2.663432e-03 -2.779607e-03 -2.900368e-03 -3.025854e-03
## ASV7557     -5.411514e-03 -5.647501e-03 -5.892799e-03 -6.147690e-03
## ASV8422      1.346991e-03  1.404849e-03  1.464921e-03  1.527269e-03
## ASV1086     -2.083225e-04 -2.164520e-04 -2.248219e-04 -2.334332e-04
## ASV1310      2.593823e-03  2.707203e-03  2.825085e-03  2.947607e-03
## ASV15750    -3.507708e-04 -3.651426e-04 -3.799930e-04 -3.953279e-04
## ASV16905    -1.112787e-03 -1.161313e-03 -1.211755e-03 -1.264168e-03
## ASV2033      4.795837e-03  5.019868e-03  5.254139e-03  5.499095e-03
## ASV2089      2.346780e-03  2.449230e-03  2.555731e-03  2.666409e-03
## ASV2127      7.623605e-03  7.956917e-03  8.303484e-03  8.663721e-03
## ASV2725      6.088676e-03  6.350751e-03  6.622872e-03  6.905319e-03
## ASV2804     -2.303378e-03 -2.403814e-03 -2.508213e-03 -2.616694e-03
## ASV3075      5.070453e-03  5.298734e-03  5.536754e-03  5.784885e-03
## ASV3327      7.034458e-03  7.358748e-03  7.697491e-03  8.051286e-03
## ASV3342      6.040628e-03  6.317305e-03  6.606163e-03  6.907697e-03
## ASV3532     -6.655219e-03 -6.956621e-03 -7.270998e-03 -7.598855e-03
## ASV3600      3.095322e-03  3.236151e-03  3.383099e-03  3.536410e-03
## ASV4013      5.757143e-03  6.013358e-03  6.280174e-03  6.557961e-03
## ASV4136      6.115148e-03  6.379159e-03  6.653392e-03  6.938145e-03
## ASV4195      2.350794e-02  2.453272e-02  2.559790e-02  2.670471e-02
## ASV4407     -9.081066e-03 -9.476842e-03 -9.888215e-03 -1.031566e-02
## ASV4717      1.568599e-03  1.632964e-03  1.699518e-03  1.768295e-03
## ASV6794      3.750688e-03  3.909971e-03  4.075190e-03  4.246499e-03
## ASV8324     -4.659731e-03 -4.862815e-03 -5.073902e-03 -5.293233e-03
## ASV8981     -1.071283e-04 -1.090884e-04 -1.108679e-04 -1.124358e-04
## ASV9859      1.649139e-03  1.731640e-03  1.818418e-03  1.909703e-03
## ASV0936      4.555090e-03  4.763930e-03  4.981962e-03  5.209553e-03
## ASV12683    -7.875406e-06 -9.096410e-06 -1.044016e-05 -1.191636e-05
## ASV1293      3.021961e-03  3.153419e-03  3.290043e-03  3.431987e-03
## ASV13055    -6.521102e-05 -6.606986e-05 -6.677384e-05 -6.729971e-05
## ASV17063    -2.416195e-03 -2.521413e-03 -2.630770e-03 -2.744391e-03
## ASV2228      1.970094e-03  2.055865e-03  2.145009e-03  2.237627e-03
## ASV2769      3.197237e-04  3.366492e-04  3.545168e-04  3.733806e-04
## ASV2803      2.122003e-03  2.211265e-03  2.303760e-03  2.399561e-03
## ASV2896      1.720505e-03  1.800131e-03  1.883352e-03  1.970326e-03
## ASV3062      2.091329e-03  2.192485e-03  2.298575e-03  2.409839e-03
## ASV3107      3.202307e-03  3.349175e-03  3.502536e-03  3.662656e-03
## ASV3265      4.322034e-03  4.509544e-03  4.704369e-03  4.906725e-03
## ASV3666      4.084489e-05  4.228764e-05  4.375126e-05  4.523237e-05
## ASV4497      1.487738e-03  1.553162e-03  1.621222e-03  1.692004e-03
## ASV6914     -2.285111e-04 -2.403656e-04 -2.528655e-04 -2.660477e-04
## ASV0576     -5.129550e-03 -5.343394e-03 -5.564807e-03 -5.793945e-03
## ASV0673      5.736824e-03  5.991127e-03  6.255856e-03  6.531365e-03
## ASV0772      2.666173e-03  2.785365e-03  2.909548e-03  3.038901e-03
## ASV0862      2.824263e-04  3.025515e-04  3.241931e-04  3.474651e-04
## ASV0898      2.087821e-03  2.186035e-03  2.288792e-03  2.396293e-03
## ASV0910      2.402434e-03  2.513233e-03  2.628981e-03  2.749886e-03
## ASV0964     -1.943246e-03 -2.025379e-03 -2.110515e-03 -2.198725e-03
## ASV10059     1.718415e-03  1.800276e-03  1.886025e-03  1.975844e-03
## ASV10263    -3.681997e-03 -3.842558e-03 -4.009457e-03 -4.182886e-03
## ASV1088      4.277384e-03  4.472862e-03  4.676938e-03  4.889965e-03
## ASV1101      5.261342e-03  5.490040e-03  5.727698e-03  5.974580e-03
## ASV1183      1.399908e-03  1.463269e-03  1.529353e-03  1.598264e-03
## ASV11956     1.337753e-03  1.393276e-03  1.450744e-03  1.510195e-03
## ASV12774     7.000927e-05  7.075237e-05  7.130832e-05  7.165076e-05
## ASV1321      6.210581e-03  6.499294e-03  6.801103e-03  7.116572e-03
## ASV13793    -2.538552e-03 -2.649236e-03 -2.764288e-03 -2.883840e-03
## ASV14482     1.589158e-04  1.650457e-04  1.713553e-04  1.778461e-04
## ASV15483     1.053046e-03  1.101469e-03  1.152038e-03  1.204841e-03
## ASV2062      4.880783e-03  5.097520e-03  5.323196e-03  5.558123e-03
## ASV2132      4.005071e-03  4.188681e-03  4.380382e-03  4.580503e-03
## ASV2413      3.765574e-03  3.930426e-03  4.101866e-03  4.280105e-03
## ASV2490      1.155041e-02  1.204394e-02  1.255606e-02  1.308727e-02
## ASV2594      1.457219e-03  1.523377e-03  1.592413e-03  1.664443e-03
## ASV2822     -6.700644e-03 -6.992967e-03 -7.296841e-03 -7.612617e-03
## ASV2863      7.118339e-03  7.425773e-03  7.745118e-03  8.076720e-03
## ASV2910      2.607916e-03  2.721437e-03  2.839429e-03  2.962025e-03
## ASV2980      2.920171e-03  3.050220e-03  3.185661e-03  3.326681e-03
## ASV3307      5.330179e-03  5.562603e-03  5.804202e-03  6.055254e-03
## ASV3474      3.561860e-03  3.729081e-03  3.904026e-03  4.087041e-03
## ASV3502      3.717733e-03  3.885402e-03  4.060219e-03  4.242454e-03
## ASV4236      5.425403e-03  5.655641e-03  5.894387e-03  6.141846e-03
## ASV4842     -5.918603e-04 -6.195099e-04 -6.483925e-04 -6.785548e-04
## ASV4894     -2.539465e-03 -2.650242e-03 -2.765395e-03 -2.885058e-03
## ASV5290      2.031246e-03  2.124020e-03  2.220849e-03  2.321892e-03
## ASV5501      1.239518e-03  1.295466e-03  1.353820e-03  1.414677e-03
## ASV5795      1.365600e-03  1.428175e-03  1.493505e-03  1.561700e-03
## ASV5987     -7.093840e-03 -7.403363e-03 -7.725124e-03 -8.059496e-03
## ASV6267     -7.992043e-03 -8.340675e-03 -8.703084e-03 -9.079689e-03
## ASV6862      3.199379e-03  3.336259e-03  3.478323e-03  3.625711e-03
## ASV7145      1.409056e-03  1.468299e-03  1.529711e-03  1.593349e-03
## ASV7673     -2.539278e-03 -2.650042e-03 -2.765181e-03 -2.884830e-03
## ASV7789      1.283160e-03  1.346762e-03  1.413603e-03  1.483853e-03
## ASV7809      9.491623e-05  1.019412e-04  1.095108e-04  1.176667e-04
## ASV8002     -3.206948e-03 -3.346836e-03 -3.492253e-03 -3.643366e-03
## ASV8205      1.351171e-03  1.412653e-03  1.476809e-03  1.543745e-03
## ASV9155     -8.128017e-04 -8.474458e-04 -8.833823e-04 -9.206433e-04
## ASV9221      3.455207e-04  3.657211e-04  3.872047e-04  4.100582e-04
## ASV9311     -5.144148e-03 -5.368518e-03 -5.601754e-03 -5.844126e-03
## ASV9557     -3.515071e-03 -3.668350e-03 -3.827683e-03 -3.993253e-03
## ASV9936     -7.087473e-03 -7.396459e-03 -7.717641e-03 -8.051391e-03
## ASV1445      4.332640e-03  4.529928e-03  4.735794e-03  4.950574e-03
## ASV4232      1.649984e-03  1.728657e-03  1.811090e-03  1.897464e-03
## ASV6479      6.027692e-04  6.363231e-04  6.718862e-04  7.095861e-04
## ASV0142     -3.052679e-03 -3.184822e-03 -3.322103e-03 -3.464672e-03
## ASV0378      1.405521e-03  1.472508e-03  1.542676e-03  1.616176e-03
## ASV1122      4.197494e-03  4.389968e-03  4.590931e-03  4.800730e-03
## ASV0123     -2.695039e-03 -2.811461e-03 -2.932387e-03 -3.057947e-03
## ASV2064      1.370997e-03  1.427478e-03  1.485879e-03  1.546228e-03
## ASV4459     -1.895903e-04 -1.966246e-04 -2.038307e-04 -2.112051e-04
## ASV0448      1.124130e-03  1.177775e-03  1.233973e-03  1.292843e-03
## ASV0397      2.460377e-03  2.570675e-03  2.685612e-03  2.805356e-03
## ASV0485      2.854432e-03  2.980676e-03  3.112083e-03  3.248825e-03
## ASV1566      4.210818e-03  4.399044e-03  4.595134e-03  4.799369e-03
## ASV1365      3.601705e-03  3.764668e-03  3.934609e-03  4.111791e-03
## ASV1065      5.117072e-03  5.348087e-03  5.588967e-03  5.840083e-03
## ASV0722     -2.685163e-04 -2.811439e-04 -2.943625e-04 -3.081999e-04
## ASV12660    -2.919195e-03 -3.044763e-03 -3.175154e-03 -3.310503e-03
## ASV0223      7.889835e-04  8.240435e-04  8.605551e-04  8.985699e-04
## ASV0229      1.209202e-03  1.264791e-03  1.322849e-03  1.383478e-03
## ASV0877      4.998778e-04  5.201422e-04  5.410432e-04  5.625815e-04
## ASV0983      2.831195e-03  2.955643e-03  3.085099e-03  3.219726e-03
## ASV0626      3.199129e-04  3.391276e-04  3.595830e-04  3.813616e-04
## ASV4146      1.389973e-04  1.449599e-04  1.511276e-04  1.575004e-04
## ASV4175     -3.506857e-03 -3.667199e-03 -3.834569e-03 -4.009248e-03
## ASV2082     -1.604735e-03 -1.687688e-03 -1.775162e-03 -1.867418e-03
## ASV2272      1.668760e-03  1.744682e-03  1.823909e-03  1.906574e-03
## ASV2245     -2.506354e-03 -2.621604e-03 -2.741960e-03 -2.867632e-03
## ASV0590     -1.520789e-03 -1.602053e-03 -1.687939e-03 -1.778726e-03
## ASV0217      1.493256e-04  1.629785e-04  1.778319e-04  1.939847e-04
## ASV0416      1.876129e-03  1.952469e-03  2.031318e-03  2.112705e-03
## ASV1056      2.428361e-03  2.541726e-03  2.660264e-03  2.784200e-03
## ASV7777     -3.410658e-03 -3.565715e-03 -3.727504e-03 -3.896291e-03
## ASV0455      6.114476e-04  6.389965e-04  6.677149e-04  6.976461e-04
## ASV0604      1.601301e-03  1.677015e-03  1.756265e-03  1.839214e-03
## ASV6100     -2.354090e-03 -2.462559e-03 -2.575869e-03 -2.694224e-03
## ASV11359    -5.052142e-03 -5.281811e-03 -5.521423e-03 -5.771365e-03
## ASV6604      7.037354e-04  7.368454e-04  7.714894e-04  8.077358e-04
## ASV5004     -1.795191e-03 -1.876159e-03 -1.960585e-03 -2.048599e-03
## ASV1483     -7.725579e-04 -8.071375e-04 -8.431662e-04 -8.806962e-04
## ASV9773     -2.277486e-03 -2.381652e-03 -2.490393e-03 -2.603897e-03
## ASV4059      1.960729e-05  2.573544e-05  3.259881e-05  4.026708e-05
## ASV1193      2.745326e-03  2.868580e-03  2.997034e-03  3.130879e-03
## ASV4610     -4.120552e-04 -4.234453e-04 -4.347053e-04 -4.457804e-04
## ASV0742     -2.434533e-04 -2.484189e-04 -2.530639e-04 -2.573308e-04
## ASV1502     -1.346774e-04 -1.445377e-04 -1.551581e-04 -1.665969e-04
## ASV0195      5.977122e-05  6.016418e-05  6.037293e-05  6.037362e-05
## ASV1213      1.917678e-03  1.997963e-03  2.081119e-03  2.167205e-03
## ASV1648     -2.113731e-03 -2.210940e-03 -2.312475e-03 -2.418518e-03
## ASV6984     -1.977957e-03 -2.069034e-03 -2.164177e-03 -2.263558e-03
## ASV0396     -1.042067e-04 -1.063535e-04 -1.083731e-04 -1.102434e-04
## ASV4297      2.788546e-03  2.907707e-03  3.031352e-03  3.159597e-03
## ASV2622      4.337965e-03  4.527681e-03  4.724954e-03  4.930021e-03
## ASV3512      1.718619e-03  1.803906e-03  1.893553e-03  1.987790e-03
## ASV2411      2.983105e-03  3.122861e-03  3.269048e-03  3.421953e-03
## ASV2291     -1.317987e-03 -1.389586e-03 -1.465338e-03 -1.545495e-03
## ASV0807      4.043752e-03  4.225396e-03  4.414708e-03  4.611965e-03
## ASV1292      9.644133e-04  1.003681e-03  1.044248e-03  1.086132e-03
## ASV1035      3.690333e-03  3.850128e-03  4.016164e-03  4.188631e-03
## ASV0070      3.964639e-05  4.395548e-05  4.868013e-05  5.385708e-05
## ASV0255      3.472124e-04  3.614036e-04  3.760601e-04  3.911860e-04
## ASV0057     -1.011244e-03 -1.053634e-03 -1.097539e-03 -1.142991e-03
## ASV0077     -2.116057e-04 -2.195172e-04 -2.276186e-04 -2.359041e-04
## ASV0625      2.122329e-03  2.213331e-03  2.307788e-03  2.405795e-03
## ASV2464      1.443152e-02  1.504751e-02  1.568676e-02  1.634991e-02
## ASV1315      3.889664e-03  4.072858e-03  4.264568e-03  4.465175e-03
## ASV2673      3.337253e-03  3.494687e-03  3.659462e-03  3.831911e-03
## ASV2161      1.410586e-03  1.476912e-03  1.546319e-03  1.618945e-03
## ASV0337     -8.046543e-04 -8.415529e-04 -8.800781e-04 -9.202959e-04
## ASV7680     -5.254172e-03 -5.495973e-03 -5.748521e-03 -6.012261e-03
## ASV0611      2.935290e-03  3.070630e-03  3.212014e-03  3.359696e-03
## ASV3118     -3.061192e-03 -3.206383e-03 -3.358406e-03 -3.517577e-03
## ASV1284      1.030154e-03  1.059999e-03  1.089604e-03  1.118824e-03
## ASV0889      2.205050e-03  2.302217e-03  2.403330e-03  2.508523e-03
## ASV4649     -1.109463e-03 -1.159728e-03 -1.212157e-03 -1.266836e-03
## ASV1108     -2.295697e-03 -2.406208e-03 -2.522071e-03 -2.643548e-03
## ASV0738      1.280950e-03  1.346314e-03  1.415160e-03  1.487685e-03
## ASV0473     -2.651361e-04 -2.800775e-04 -2.959107e-04 -3.126899e-04
## ASV0598     -6.590845e-04 -6.940708e-04 -7.310376e-04 -7.701046e-04
## ASV0429      1.632015e-03  1.702576e-03  1.775861e-03  1.851945e-03
## ASV1549      3.080048e-03  3.225588e-03  3.377936e-03  3.537402e-03
## ASV1203      2.399680e-03  2.505866e-03  2.616390e-03  2.731399e-03
## ASV4532      9.929740e-05  1.025958e-04  1.059382e-04  1.093192e-04
## ASV0274      4.259049e-04  4.469198e-04  4.689867e-04  4.921576e-04
## ASV0163     -1.842743e-03 -1.921425e-03 -2.003073e-03 -2.087765e-03
## ASV1298      1.977941e-04  2.052133e-04  2.128308e-04  2.206462e-04
## ASV9424     -4.076926e-03 -4.265623e-03 -4.462818e-03 -4.668873e-03
## ASV0412      4.158391e-03  4.341116e-03  4.531203e-03  4.728892e-03
## ASV0284      8.552340e-04  8.889708e-04  9.237111e-04  9.594541e-04
## ASV0620     -8.763151e-04 -9.210498e-04 -9.681633e-04 -1.017787e-03
## ASV0153     -4.117625e-03 -4.312097e-03 -4.515650e-03 -4.728695e-03
## ASV0498      1.446453e-03  1.513064e-03  1.582627e-03  1.655259e-03
## ASV0097      8.088477e-04  8.470415e-04  8.870210e-04  9.288679e-04
## ASV0104     -5.662063e-03 -5.915034e-03 -6.178554e-03 -6.452999e-03
## ASV1282      1.940274e-03  2.023714e-03  2.110325e-03  2.200192e-03
## ASV3883     -1.580168e-03 -1.657692e-03 -1.739078e-03 -1.824520e-03
## ASV0801      7.712643e-04  8.067400e-04  8.437880e-04  8.824728e-04
## ASV1611     -3.661635e-03 -3.832816e-03 -4.011849e-03 -4.199078e-03
## ASV0227     -6.774930e-04 -7.133315e-04 -7.511707e-04 -7.911275e-04
## ASV0833      1.240432e-03  1.297216e-03  1.356490e-03  1.418354e-03
## ASV0718      5.544694e-03  5.797399e-03  6.061123e-03  6.336304e-03
## ASV1139      6.888693e-04  7.135742e-04  7.387494e-04  7.643600e-04
## ASV0766     -7.862653e-04 -8.249595e-04 -8.655881e-04 -9.082480e-04
## ASV2091      4.457923e-03  4.649292e-03  4.847940e-03  5.054065e-03
## ASV1238     -4.136346e-03 -4.328263e-03 -4.528883e-03 -4.738586e-03
## ASV9193     -4.180027e-04 -4.427517e-04 -4.691041e-04 -4.971712e-04
## ASV0290      5.716828e-04  5.937122e-04  6.163547e-04  6.396066e-04
## ASV0231      1.636817e-03  1.708699e-03  1.783468e-03  1.861217e-03
## ASV0185      9.819876e-04  1.031880e-03  1.084414e-03  1.139738e-03
## ASV2330      1.862944e-03  1.941495e-03  2.022902e-03  2.107232e-03
## ASV3119     -8.879454e-04 -9.327419e-04 -9.798817e-04 -1.029492e-03
## ASV2368     -2.131659e-03 -2.232703e-03 -2.338521e-03 -2.449336e-03
## ASV0122     -1.019286e-03 -1.064541e-03 -1.111662e-03 -1.160714e-03
## ASV1044      2.638428e-03  2.761835e-03  2.890908e-03  3.025899e-03
## ASV0160     -1.084981e-03 -1.130858e-03 -1.178419e-03 -1.227704e-03
## ASV0326      2.909920e-04  3.043385e-04  3.182699e-04  3.328090e-04
## ASV1388      5.291646e-03  5.527539e-03  5.773225e-03  6.029045e-03
## ASV0792      3.909109e-03  4.079058e-03  4.255674e-03  4.439158e-03
## ASV0036     -1.235380e-03 -1.293763e-03 -1.354873e-03 -1.418831e-03
## ASV2125      3.787474e-03  3.957490e-03  4.134673e-03  4.319282e-03
## ASV1075     -5.704134e-05 -5.962452e-05 -6.232401e-05 -6.514547e-05
## ASV0390      2.040005e-03  2.136432e-03  2.237383e-03  2.343067e-03
## ASV3790     -2.882013e-03 -3.014490e-03 -3.152844e-03 -3.297316e-03
## ASV1535     -8.448580e-04 -8.871381e-04 -9.316017e-04 -9.783651e-04
## ASV0263      3.520663e-03  3.680206e-03  3.846619e-03  4.020166e-03
## ASV0675      5.313224e-03  5.559777e-03  5.817472e-03  6.086788e-03
## ASV3348      4.349156e-04  4.561697e-04  4.784769e-04  5.018897e-04
## ASV0058     -1.564166e-03 -1.633661e-03 -1.706020e-03 -1.781340e-03
## ASV4142      2.184757e-03  2.279390e-03  2.377690e-03  2.479760e-03
## ASV0059     -1.258368e-03 -1.313856e-03 -1.371591e-03 -1.431647e-03
## ASV0013     -2.246807e-03 -2.348404e-03 -2.454353e-03 -2.564820e-03
## ASV0033     -1.073144e-03 -1.123680e-03 -1.176560e-03 -1.231891e-03
## ASV4354     -1.324037e-03 -1.384081e-03 -1.446729e-03 -1.512085e-03
## ASV0022     -9.060553e-04 -9.486807e-04 -9.932816e-04 -1.039946e-03
## ASV0134     -8.672507e-04 -9.094546e-04 -9.537392e-04 -1.000208e-03
## ASV0415      1.428527e-04  1.506746e-04  1.589453e-04  1.676908e-04
## ASV10103    -5.020789e-03 -5.253888e-03 -5.497532e-03 -5.752172e-03
## ASV1613      3.706701e-03  3.868003e-03  4.035636e-03  4.209788e-03
## ASV0135     -4.734680e-04 -4.932723e-04 -5.137792e-04 -5.350027e-04
## ASV0469     -4.796209e-03 -5.008156e-03 -5.228759e-03 -5.458312e-03
## ASV0471      2.928787e-03  3.060830e-03  3.198495e-03  3.341991e-03
## ASV0451     -4.961164e-04 -5.231206e-04 -5.516940e-04 -5.819326e-04
## ASV0747      1.670526e-03  1.746884e-03  1.826584e-03  1.909759e-03
## ASV1314     -1.688551e-03 -1.768740e-03 -1.852724e-03 -1.940681e-03
## ASV0425     -5.916677e-03 -6.172324e-03 -6.437858e-03 -6.713562e-03
## ASV0559     -1.472237e-03 -1.538321e-03 -1.607214e-03 -1.679026e-03
## ASV0148     -3.226159e-04 -3.340523e-04 -3.456887e-04 -3.575063e-04
## ASV0129      3.656265e-04  3.881235e-04  4.121349e-04  4.377687e-04
## ASV1072      3.881269e-04  4.036064e-04  4.195564e-04  4.359770e-04
## ASV2390      3.021692e-03  3.149409e-03  3.281778e-03  3.418902e-03
## ASV0548      2.014259e-03  2.104769e-03  2.199103e-03  2.297401e-03
## ASV0168     -1.030947e-03 -1.076393e-03 -1.123682e-03 -1.172876e-03
## ASV0066     -1.163019e-03 -1.214721e-03 -1.268553e-03 -1.324588e-03
## ASV0468     -6.181918e-04 -6.463056e-04 -6.756412e-04 -7.062470e-04
## ASV0172     -3.426704e-04 -3.562326e-04 -3.701987e-04 -3.845681e-04
## ASV0236     -3.857634e-05 -3.270265e-05 -2.588559e-05 -1.802761e-05
## ASV0250      1.668565e-03  1.750818e-03  1.837225e-03  1.928002e-03
## ASV0338      7.858218e-04  8.229064e-04  8.617054e-04  9.022930e-04
## ASV0450     -1.519644e-04 -1.605311e-04 -1.696186e-04 -1.792604e-04
## ASV0377      1.452208e-03  1.516570e-03  1.583569e-03  1.653297e-03
## ASV1022     -6.078692e-05 -6.319042e-05 -6.565844e-05 -6.818899e-05
## ASV6174     -3.479594e-05 -3.720843e-05 -3.980840e-05 -4.261146e-05
## ASV0786     -2.142503e-04 -2.270964e-04 -2.407679e-04 -2.553192e-04
## ASV0053     -1.577362e-03 -1.649055e-03 -1.723851e-03 -1.801870e-03
## ASV0697     -9.527847e-04 -9.942458e-04 -1.037343e-03 -1.082126e-03
## ASV0785      2.011884e-03  2.101125e-03  2.194032e-03  2.290729e-03
## ASV1967     -1.996313e-03 -2.084130e-03 -2.175506e-03 -2.270561e-03
## ASV0385      6.810732e-04  7.135960e-04  7.476611e-04  7.833392e-04
## ASV0295      1.278615e-04  1.360124e-04  1.447305e-04  1.540575e-04
## ASV0072     -1.559639e-03 -1.627767e-03 -1.698591e-03 -1.772193e-03
## ASV0157     -1.874109e-04 -1.923286e-04 -1.971273e-04 -2.017721e-04
## ASV0501      3.407895e-03  3.563356e-03  3.725596e-03  3.894883e-03
## ASV10729    -4.288238e-03 -4.485319e-03 -4.691135e-03 -4.906046e-03
## ASV1470      2.155532e-03  2.246024e-03  2.339762e-03  2.436816e-03
## ASV0050     -3.681794e-03 -3.845598e-03 -4.016171e-03 -4.193747e-03
## ASV0411     -8.381403e-04 -8.774507e-04 -9.185743e-04 -9.615918e-04
## ASV0549      1.344608e-03  1.406929e-03  1.472058e-03  1.540114e-03
## ASV0184      4.466538e-04  4.665758e-04  4.873327e-04  5.089557e-04
## ASV0705      8.805695e-04  9.190222e-04  9.589944e-04  1.000532e-03
## ASV1715      1.874062e-03  1.959095e-03  2.047796e-03  2.140308e-03
## ASV0603      2.936857e-04  3.074840e-04  3.219290e-04  3.370516e-04
## ASV0826      3.157303e-03  3.298661e-03  3.445951e-03  3.599388e-03
## ASV0034     -1.007941e-03 -1.052117e-03 -1.098057e-03 -1.145816e-03
## ASV0838      6.692816e-04  6.912164e-04  7.133092e-04  7.354922e-04
## ASV0614     -8.641999e-04 -9.028213e-04 -9.430589e-04 -9.849709e-04
## ASV0014     -2.292329e-03 -2.395351e-03 -2.502727e-03 -2.614618e-03
## ASV0585      2.322274e-04  2.364161e-04  2.402143e-04  2.435567e-04
## ASV0016     -2.394647e-03 -2.502263e-03 -2.614428e-03 -2.731308e-03
## ASV5394     -1.799693e-03 -1.881825e-03 -1.967544e-03 -2.056991e-03
## ASV0666      3.895852e-03  4.064944e-03  4.240648e-03  4.423161e-03
## ASV2085      8.663080e-04  8.948774e-04  9.237211e-04  9.527666e-04
## ASV0003     -1.632617e-03 -1.705908e-03 -1.782291e-03 -1.861877e-03
## ASV0346      8.280442e-04  8.673356e-04  9.084707e-04  9.515328e-04
## ASV0267      2.792057e-07  2.381225e-06  4.763913e-06  7.454834e-06
## ASV0353      1.312932e-03  1.374249e-03  1.438372e-03  1.505422e-03
## ASV2419      3.509510e-03  3.665595e-03  3.828135e-03  3.997354e-03
## ASV0447      1.926016e-03  2.016274e-03  2.110681e-03  2.209420e-03
## ASV0654      2.836316e-03  2.964046e-03  3.097195e-03  3.235964e-03
## ASV0151      3.868629e-04  4.068053e-04  4.278292e-04  4.499966e-04
## ASV0065     -1.095742e-03 -1.144517e-03 -1.195312e-03 -1.248197e-03
## ASV0527      2.696825e-03  2.817638e-03  2.943526e-03  3.074673e-03
## ASV4055     -4.328337e-04 -4.541628e-04 -4.765776e-04 -5.001366e-04
## ASV0166     -1.348556e-03 -1.407075e-03 -1.467881e-03 -1.531040e-03
## ASV0417     -5.477027e-04 -5.702350e-04 -5.935313e-04 -6.176029e-04
## ASV0078     -8.000895e-04 -8.351057e-04 -8.715130e-04 -9.093538e-04
## ASV0322     -1.403070e-04 -1.445613e-04 -1.487868e-04 -1.529605e-04
## ASV0156     -1.917290e-03 -2.005427e-03 -2.097479e-03 -2.193608e-03
## ASV0648     -4.166836e-03 -4.359445e-03 -4.560692e-03 -4.770939e-03
## ASV0407     -3.138817e-04 -3.288393e-04 -3.445099e-04 -3.609273e-04
## ASV2030     -6.894368e-04 -7.199074e-04 -7.516547e-04 -7.847296e-04
## ASV0300      4.994333e-04  5.231456e-04  5.479751e-04  5.739732e-04
## ASV1150      1.141205e-04  1.201056e-04  1.264198e-04  1.330817e-04
## ASV0958      1.543940e-03  1.617494e-03  1.694547e-03  1.775266e-03
## ASV0216     -1.689731e-03 -1.764477e-03 -1.842294e-03 -1.923291e-03
## ASV0446      2.567890e-03  2.686596e-03  2.810617e-03  2.940175e-03
## ASV0367     -1.679094e-03 -1.755689e-03 -1.835628e-03 -1.919044e-03
## ASV0200     -9.985323e-04 -1.043992e-03 -1.091427e-03 -1.140914e-03
## ASV0334     -5.290560e-04 -5.493282e-04 -5.701517e-04 -5.915212e-04
## ASV1311      6.450884e-04  6.711928e-04  6.981368e-04  7.259273e-04
## ASV0458      9.513419e-04  9.892225e-04  1.028275e-03  1.068505e-03
## ASV1371      1.596526e-04  1.676056e-04  1.759609e-04  1.847388e-04
## ASV0418      2.207246e-03  2.302447e-03  2.401320e-03  2.503969e-03
## ASV0004      3.196569e-04  3.333429e-04  3.475469e-04  3.622827e-04
## ASV1943      6.049691e-03  6.286690e-03  6.530786e-03  6.782010e-03
## ASV1495     -4.650732e-04 -4.920163e-04 -5.206563e-04 -5.511070e-04
## ASV0901     -1.892253e-03 -1.980446e-03 -2.072666e-03 -2.169090e-03
## ASV0628      9.895899e-04  1.030896e-03  1.073657e-03  1.117901e-03
## ASV0400      6.055676e-04  6.319262e-04  6.593163e-04  6.877680e-04
## ASV0116     -5.562107e-04 -5.820600e-04 -6.090824e-04 -6.373285e-04
## ASV0788      4.918821e-03  5.148109e-03  5.387863e-03  5.638542e-03
## ASV0117      3.644281e-04  3.819971e-04  4.004180e-04  4.197318e-04
## ASV3137     -1.139822e-04 -1.189561e-04 -1.241266e-04 -1.294998e-04
## ASV0001      3.428730e-04  3.574470e-04  3.725621e-04  3.882314e-04
## ASV1651      9.786714e-04  1.020787e-03  1.064516e-03  1.109904e-03
## ASV1692      4.095043e-03  4.285486e-03  4.484575e-03  4.692686e-03
## ASV0660      1.435226e-03  1.494258e-03  1.555278e-03  1.618312e-03
## ASV0508      7.165346e-05  7.450177e-05  7.743829e-05  8.046357e-05
## ASV1660     -8.339589e-04 -8.752755e-04 -9.186796e-04 -9.642774e-04
## ASV0233      1.260323e-03  1.317640e-03  1.377443e-03  1.439832e-03
## ASV1343     -2.330814e-03 -2.438825e-03 -2.551709e-03 -2.669673e-03
## ASV0209      1.147155e-03  1.196046e-03  1.246765e-03  1.299357e-03
## ASV0193     -1.341040e-03 -1.398709e-03 -1.458577e-03 -1.520706e-03
## ASV0357      5.298493e-04  5.571243e-04  5.858807e-04  6.162044e-04
## ASV0198      1.022726e-03  1.068006e-03  1.115141e-03  1.164196e-03
## ASV0007      3.018693e-04  3.144542e-04  3.274828e-04  3.409638e-04
## ASV1772     -4.469381e-04 -4.649062e-04 -4.834208e-04 -5.024797e-04
## ASV0009      2.486668e-04  2.588124e-04  2.692944e-04  2.801170e-04
## ASV0006     -2.787556e-04 -2.921146e-04 -3.061149e-04 -3.207870e-04
## ASV0011     -9.604485e-04 -1.004714e-03 -1.050953e-03 -1.099246e-03
## ASV0015      1.879104e-04  1.955666e-04  2.034750e-04  2.116385e-04
## ASV0017      2.117577e-04  2.204050e-04  2.293399e-04  2.385663e-04
## ASV0235     -8.884187e-04 -9.296423e-04 -9.727257e-04 -1.017748e-03
## ASV0382      6.953256e-04  7.275363e-04  7.611835e-04  7.963248e-04
## ASV2357      2.892673e-03  3.025798e-03  3.164846e-03  3.310062e-03
## ASV0567     -5.613279e-04 -5.874597e-04 -6.147886e-04 -6.433687e-04
## ASV0165      4.825857e-04  5.047798e-04  5.279573e-04  5.521582e-04
## ASV0005      6.974609e-04  7.287689e-04  7.613953e-04  7.953881e-04
## ASV0384     -6.961844e-05 -7.094424e-05 -7.215799e-05 -7.323983e-05
## ASV0002      1.297805e-04  1.354019e-04  1.412434e-04  1.473116e-04
## ASV3017      3.671123e-03  3.829352e-03  3.993656e-03  4.164205e-03
## ASV0091     -9.335730e-05 -9.747515e-05 -1.017634e-04 -1.062285e-04
## ASV0186     -1.407290e-03 -1.470876e-03 -1.537177e-03 -1.606294e-03
## ASV0370      7.438956e-04  7.767898e-04  8.110233e-04  8.466406e-04
## ASV0018      8.940133e-04  9.342925e-04  9.762820e-04  1.020045e-03
## ASV1377      8.916632e-03  9.304926e-03  9.708515e-03  1.012786e-02
## ASV0019      9.380626e-04  9.803734e-04  1.024485e-03  1.070466e-03
## ASV0023     -5.893609e-04 -6.167814e-04 -6.454461e-04 -6.754082e-04
## ASV2194      9.494106e-04  9.941803e-04  1.041043e-03  1.090094e-03
## ASV1155      3.728852e-03  3.890892e-03  4.059347e-03  4.234424e-03
## ASV0510     -9.910050e-04 -1.031589e-03 -1.073529e-03 -1.116841e-03
## ASV2371     -2.245678e-03 -2.343300e-03 -2.444777e-03 -2.550231e-03
## ASV0024     -7.334576e-04 -7.674633e-04 -8.030016e-04 -8.401373e-04
## ASV2452      2.243620e-03  2.337479e-03  2.434667e-03  2.535248e-03
## ASV2332     -6.459376e-03 -6.743185e-03 -7.038483e-03 -7.345655e-03
## ASV2591      1.731602e-03  1.819207e-03  1.911335e-03  2.008218e-03
## ASV0521      1.489838e-03  1.558821e-03  1.630909e-03  1.706233e-03
## ASV5542      1.426417e-03  1.492474e-03  1.561480e-03  1.633557e-03
## ASV0336     -1.867609e-04 -1.974371e-04 -2.087680e-04 -2.207957e-04
## ASV10102     2.634495e-03  2.756293e-03  2.883540e-03  3.016463e-03
## ASV16823    -4.012290e-03 -4.181929e-03 -4.357846e-03 -4.540201e-03
## ASV3104      2.075598e-02  2.163335e-02  2.254317e-02  2.348626e-02
## ASV0781      2.925313e-03  3.056845e-03  3.193947e-03  3.336822e-03
## ASV10899     1.753549e-03  1.842925e-03  1.937030e-03  2.036122e-03
## ASV11222    -7.059869e-03 -7.358268e-03 -7.667703e-03 -7.988454e-03
## ASV11327    -6.337149e-03 -6.604942e-03 -6.882633e-03 -7.170475e-03
## ASV12458    -7.056827e-03 -7.354966e-03 -7.664119e-03 -7.984567e-03
## ASV1636      4.009561e-03  4.185356e-03  4.368181e-03  4.558259e-03
## ASV1890     -3.225310e-03 -3.355656e-03 -3.490293e-03 -3.629285e-03
## ASV2898      5.377061e-03  5.613120e-03  5.858658e-03  6.113981e-03
## ASV8328      6.913996e-04  7.391281e-04  7.903556e-04  8.453405e-04
## ASV0709     -6.008654e-03 -6.276600e-03 -6.555658e-03 -6.846215e-03
## ASV0856      5.031246e-03  5.268328e-03  5.516417e-03  5.776005e-03
## ASV0909      1.484253e-03  1.564384e-03  1.649123e-03  1.738749e-03
## ASV0937     -3.549956e-03 -3.713835e-03 -3.885081e-03 -4.064012e-03
## ASV11390    -1.006988e-02 -1.049526e-02 -1.093634e-02 -1.139353e-02
## ASV11966     2.472721e-03  2.591988e-03  2.717012e-03  2.848064e-03
## ASV12990     1.765313e-03  1.842031e-03  1.921736e-03  2.004514e-03
## ASV14797     2.610606e-03  2.722708e-03  2.839082e-03  2.959844e-03
## ASV14904    -1.444932e-02 -1.505967e-02 -1.569256e-02 -1.634857e-02
## ASV15304     1.558595e-03  1.636800e-03  1.719022e-03  1.805468e-03
## ASV16696    -4.991739e-03 -5.202563e-03 -5.421172e-03 -5.647763e-03
## ASV1690      8.553357e-03  8.957446e-03  9.380298e-03  9.822738e-03
## ASV2029      5.903191e-03  6.165316e-03  6.438253e-03  6.722380e-03
## ASV2834      7.429650e-03  7.770058e-03  8.125444e-03  8.496410e-03
## ASV4003      6.151807e-03  6.449224e-03  6.761152e-03  7.088306e-03
## ASV4064      3.529588e-03  3.692615e-03  3.862920e-03  4.040802e-03
## ASV4294      2.157072e-03  2.265287e-03  2.379095e-03  2.498792e-03
## ASV4609      1.995400e-03  2.083537e-03  2.175252e-03  2.270665e-03
## ASV6283     -4.666781e-03 -4.863922e-03 -5.068348e-03 -5.280244e-03
## ASV6491     -6.687509e-03 -6.969950e-03 -7.262822e-03 -7.566391e-03
## ASV7453      3.282011e-03  3.441267e-03  3.608288e-03  3.783447e-03
## ASV7959      1.196409e-03  1.260503e-03  1.328218e-03  1.399768e-03
## ASV8219      5.778870e-02  6.022919e-02  6.275982e-02  6.538287e-02
## ASV8547     -5.985473e-03 -6.238191e-03 -6.500239e-03 -6.771852e-03
## ASV9319      2.637505e-03  2.761327e-03  2.890861e-03  3.026359e-03
## ASV9382     -1.170997e-02 -1.220434e-02 -1.271695e-02 -1.324827e-02
## ASV11516    -7.819638e-03 -8.149691e-03 -8.491919e-03 -8.846631e-03
## ASV14377    -5.644987e-03 -5.883199e-03 -6.130194e-03 -6.386194e-03
## ASV1867      4.415823e-03  4.619769e-03  4.832836e-03  5.055404e-03
## ASV1895      2.194485e-03  2.286318e-03  2.381385e-03  2.479744e-03
## ASV3168      2.769719e-03  2.888594e-03  3.011963e-03  3.139939e-03
## ASV4449      1.533096e-02  1.601923e-02  1.673669e-02  1.748445e-02
## ASV6596      3.224602e-03  3.382774e-03  3.548849e-03  3.723230e-03
## ASV7492     -5.490825e-04 -5.613877e-04 -5.731411e-04 -5.842326e-04
## ASV9854     -1.204787e-03 -1.254712e-03 -1.306412e-03 -1.359930e-03
## ASV6296      9.470157e-02  9.869690e-02  1.028395e-01  1.071330e-01
## ASV4201      4.939019e-04  5.292585e-04  5.672803e-04  6.081676e-04
## ASV0552      3.053907e-03  3.194282e-03  3.340874e-03  3.493938e-03
## ASV3671     -2.026665e-03 -2.116533e-03 -2.210149e-03 -2.307655e-03
## ASV3529     -5.029181e-04 -5.156164e-04 -5.280226e-04 -5.400605e-04
## ASV1060      8.154739e-04  8.541962e-04  8.947551e-04  9.372378e-04
## ASV0239     -1.086424e-03 -1.131629e-03 -1.178425e-03 -1.226844e-03
## ASV5711     -4.949248e-03 -5.166731e-03 -5.393028e-03 -5.628438e-03
## ASV4152     -7.025125e-03 -7.343720e-03 -7.676086e-03 -8.022763e-03
## ASV1461      3.509268e-03  3.656580e-03  3.809186e-03  3.967200e-03
## ASV2877      1.825240e-03  1.902884e-03  1.983408e-03  2.066880e-03
## ASV0012      3.172702e-04  3.315974e-04  3.465379e-04  3.621151e-04
## ASV9823      4.400094e-04  4.556785e-04  4.716217e-04  4.878123e-04
## ASV0008      3.381513e-04  3.533113e-04  3.691109e-04  3.855739e-04
## ASV7832     -4.138652e-03 -4.327513e-03 -4.524675e-03 -4.730481e-03
## ASV1915     -5.215025e-04 -5.439792e-04 -5.673499e-04 -5.916463e-04
## ASV0055     -3.700602e-04 -3.886290e-04 -4.081602e-04 -4.287052e-04
## ASV0032      1.658607e-04  1.721916e-04  1.786907e-04  1.853556e-04
## ASV2977     -5.825819e-03 -6.088915e-03 -6.363282e-03 -6.649351e-03
## ASV0466      4.643887e-03  4.839091e-03  5.041347e-03  5.250809e-03
## ASV3866      3.212117e-03  3.361521e-03  3.517709e-03  3.680977e-03
## ASV0040      1.157772e-03  1.210644e-03  1.265830e-03  1.323423e-03
## ASV0496     -2.906058e-04 -3.097948e-04 -3.303500e-04 -3.523710e-04
## ASV0052      9.722078e-04  1.016673e-03  1.063090e-03  1.111536e-03
## ASV3828     -3.353041e-03 -3.494009e-03 -3.640127e-03 -3.791521e-03
## ASV1930      1.726167e-03  1.801193e-03  1.879143e-03  1.960102e-03
## ASV2126      2.949882e-03  3.080981e-03  3.217496e-03  3.359615e-03
## ASV0793      3.636667e-03  3.804993e-03  3.980882e-03  4.164653e-03
## ASV0299     -7.201100e-05 -7.558175e-05 -7.935109e-05 -8.333313e-05
## ASV0208      2.621480e-03  2.741139e-03  2.866034e-03  2.996377e-03
## ASV0511     -1.066814e-03 -1.110980e-03 -1.156668e-03 -1.203904e-03
## ASV1123     -3.231878e-03 -3.367243e-03 -3.507469e-03 -3.652661e-03
## ASV0099      9.988330e-05  1.051684e-04  1.107558e-04  1.166647e-04
## ASV0752     -1.875056e-03 -1.964025e-03 -2.057177e-03 -2.154705e-03
## ASV0883      2.570483e-03  2.691867e-03  2.818907e-03  2.951858e-03
## ASV0683      3.355950e-03  3.512722e-03  3.676663e-03  3.848086e-03
## ASV4117     -5.331187e-03 -5.574350e-03 -5.828169e-03 -6.093078e-03
## ASV2172      3.389520e-04  3.516690e-04  3.646894e-04  3.780025e-04
## ASV0330     -9.972884e-04 -1.043232e-03 -1.091224e-03 -1.141350e-03
## ASV0728      4.914460e-03  5.135896e-03  5.366729e-03  5.607306e-03
## ASV0499      1.306629e-03  1.367933e-03  1.432067e-03  1.499159e-03
## ASV0120     -2.180346e-03 -2.278838e-03 -2.381531e-03 -2.488584e-03
## ASV1446      1.646050e-03  1.709629e-03  1.774985e-03  1.842104e-03
## ASV17171    -4.210198e-03 -4.399721e-03 -4.597341e-03 -4.803370e-03
## ASV0533      3.168503e-04  3.324215e-04  3.487721e-04  3.659416e-04
## ASV2495     -1.046889e-03 -1.100272e-03 -1.156519e-03 -1.215795e-03
## ASV5582      1.922967e-03  2.000152e-03  2.079776e-03  2.161858e-03
## ASV1488      7.403293e-04  7.723350e-04  8.055709e-04  8.400700e-04
## ASV0682      9.526885e-04  9.976645e-04  1.044739e-03  1.094007e-03
## ASV0068     -1.652270e-03 -1.727308e-03 -1.805584e-03 -1.887225e-03
## ASV1987     -4.136016e-03 -4.332973e-03 -4.539255e-03 -4.755295e-03
## ASV0035     -3.148088e-04 -3.329568e-04 -3.522511e-04 -3.727701e-04
## ASV7192     -2.550026e-03 -2.662310e-03 -2.779149e-03 -2.900697e-03
## ASV0873     -4.662265e-04 -5.566568e-04 -6.568385e-04 -7.676138e-04
## ASV4749     -1.131071e-04 -1.303030e-04 -1.493293e-04 -1.703529e-04
## ASV2174      1.759040e-03  1.830763e-03  1.904856e-03  1.981348e-03
## ASV1476     -1.831304e-03 -1.917586e-03 -2.007903e-03 -2.102444e-03
## ASV0740     -5.198097e-03 -5.442251e-03 -5.697702e-03 -5.964959e-03
## ASV0170     -1.013682e-03 -1.059796e-03 -1.107914e-03 -1.158112e-03
## ASV2466     -4.621928e-03 -4.832364e-03 -5.051983e-03 -5.281153e-03
## ASV1709      1.686067e-03  1.759286e-03  1.835434e-03  1.914616e-03
## ASV6170     -7.252434e-03 -7.588994e-03 -7.940770e-03 -8.308417e-03
## ASV3673      3.566279e-03  3.733710e-03  3.908880e-03  4.092137e-03
## ASV1745     -9.280483e-04 -9.734517e-04 -1.021114e-03 -1.071150e-03
##                                                                    
## (Intercept)  2.940797e-02  3.073345e-02  3.211512e-02  3.355505e-02
## ASV1236      5.746326e-03  5.993375e-03  6.249925e-03  6.516249e-03
## ASV0421      7.001281e-04  7.386699e-04  7.794626e-04  8.226414e-04
## ASV0691     -4.384980e-03 -4.556897e-03 -4.733950e-03 -4.916158e-03
## ASV0899      4.986616e-03  5.202087e-03  5.425871e-03  5.658202e-03
## ASV1004      1.151615e-02  1.201313e-02  1.252933e-02  1.306528e-02
## ASV1041     -4.728044e-03 -4.930379e-03 -5.140314e-03 -5.358041e-03
## ASV1058      7.184223e-03  7.493651e-03  7.815004e-03  8.148628e-03
## ASV12542     2.768335e-03  2.884289e-03  3.004425e-03  3.128839e-03
## ASV1294      6.688879e-03  6.977515e-03  7.277323e-03  7.588631e-03
## ASV13113     2.292424e-03  2.402207e-03  2.517257e-03  2.637826e-03
## ASV1318      6.668114e-03  6.955475e-03  7.253912e-03  7.563744e-03
## ASV2269     -1.153480e-02 -1.202960e-02 -1.254322e-02 -1.307616e-02
## ASV2542      5.715020e-03  5.977928e-03  6.252530e-03  6.539311e-03
## ASV2660     -4.582990e-03 -4.778265e-03 -4.980859e-03 -5.190960e-03
## ASV2737      1.568601e-03  1.632104e-03  1.697710e-03  1.765450e-03
## ASV2840      6.068969e-03  6.319744e-03  6.579179e-03  6.847427e-03
## ASV3053      3.117708e-02  3.248721e-02  3.384496e-02  3.525146e-02
## ASV3077      1.990887e-03  2.075024e-03  2.162271e-03  2.252707e-03
## ASV3134      3.643246e-03  3.814684e-03  3.994092e-03  4.181830e-03
## ASV3140      4.885065e-03  5.104843e-03  5.333931e-03  5.572674e-03
## ASV3579      1.773440e-03  1.861061e-03  1.953103e-03  2.049793e-03
## ASV6119     -3.156206e-03 -3.291562e-03 -3.432062e-03 -3.577846e-03
## ASV7557     -6.412458e-03 -6.687384e-03 -6.972752e-03 -7.268843e-03
## ASV8422      1.591956e-03  1.659044e-03  1.728594e-03  1.800669e-03
## ASV1086     -2.422864e-04 -2.513813e-04 -2.607173e-04 -2.702933e-04
## ASV1310      3.074912e-03  3.207139e-03  3.344431e-03  3.486929e-03
## ASV15750    -4.111518e-04 -4.274683e-04 -4.442799e-04 -4.615875e-04
## ASV16905    -1.318613e-03 -1.375147e-03 -1.433828e-03 -1.494714e-03
## ASV2033      5.755198e-03  6.022928e-03  6.302783e-03  6.595278e-03
## ASV2089      2.781386e-03  2.900786e-03  3.024735e-03  3.153355e-03
## ASV2127      9.038046e-03  9.426879e-03  9.830645e-03  1.024977e-02
## ASV2725      7.198371e-03  7.502304e-03  7.817393e-03  8.143907e-03
## ASV2804     -2.729377e-03 -2.846383e-03 -2.967833e-03 -3.093846e-03
## ASV3075      6.043513e-03  6.313034e-03  6.593858e-03  6.886405e-03
## ASV3327      8.420752e-03  8.806530e-03  9.209284e-03  9.629697e-03
## ASV3342      7.222416e-03  7.550847e-03  7.893535e-03  8.251040e-03
## ASV3532     -7.940708e-03 -8.297090e-03 -8.668549e-03 -9.055648e-03
## ASV3600      3.696331e-03  3.863120e-03  4.037041e-03  4.218368e-03
## ASV4013      6.847096e-03  7.147962e-03  7.460949e-03  7.786453e-03
## ASV4136      7.233717e-03  7.540407e-03  7.858515e-03  8.188338e-03
## ASV4195      2.785438e-02  2.904813e-02  3.028719e-02  3.157277e-02
## ASV4407     -1.075964e-02 -1.122063e-02 -1.169911e-02 -1.219555e-02
## ASV4717      1.839329e-03  1.912652e-03  1.988292e-03  2.066271e-03
## ASV6794      4.424049e-03  4.607991e-03  4.798473e-03  4.995641e-03
## ASV8324     -5.521052e-03 -5.757600e-03 -6.003120e-03 -6.257853e-03
## ASV8981     -1.137583e-04 -1.147981e-04 -1.155143e-04 -1.158624e-04
## ASV9859      2.005743e-03  2.106796e-03  2.213135e-03  2.325051e-03
## ASV0936      5.447085e-03  5.694948e-03  5.953546e-03  6.223295e-03
## ASV12683    -1.353527e-05 -1.530764e-05 -1.724477e-05 -1.935847e-05
## ASV1293      3.579408e-03  3.732462e-03  3.891307e-03  4.056097e-03
## ASV13055    -6.762199e-05 -6.771280e-05 -6.754169e-05 -6.707551e-05
## ASV17063    -2.862400e-03 -2.984922e-03 -3.112082e-03 -3.244003e-03
## ASV2228      2.333819e-03  2.433688e-03  2.537335e-03  2.644861e-03
## ASV2769      3.932976e-04  4.143283e-04  4.365360e-04  4.599875e-04
## ASV2803      2.498741e-03  2.601366e-03  2.707502e-03  2.817212e-03
## ASV2896      2.061213e-03  2.156184e-03  2.255414e-03  2.359086e-03
## ASV3062      2.526531e-03  2.648913e-03  2.777265e-03  2.911874e-03
## ASV3107      3.829812e-03  4.004290e-03  4.186385e-03  4.376403e-03
## ASV3265      5.116827e-03  5.334889e-03  5.561126e-03  5.795750e-03
## ASV3666      4.672705e-05  4.823079e-05  4.973845e-05  5.124418e-05
## ASV4497      1.765596e-03  1.842084e-03  1.921558e-03  2.004107e-03
## ASV6914     -2.799506e-04 -2.946152e-04 -3.100843e-04 -3.264035e-04
## ASV0576     -6.030953e-03 -6.275970e-03 -6.529128e-03 -6.790547e-03
## ASV0673      6.818014e-03  7.116168e-03  7.426199e-03  7.748481e-03
## ASV0772      3.173609e-03  3.313863e-03  3.459855e-03  3.611782e-03
## ASV0862      3.724889e-04  3.993946e-04  4.283206e-04  4.594144e-04
## ASV0898      2.508745e-03  2.626366e-03  2.749380e-03  2.878021e-03
## ASV0910      2.876162e-03  3.008030e-03  3.145721e-03  3.289474e-03
## ASV0964     -2.290077e-03 -2.384635e-03 -2.482462e-03 -2.583618e-03
## ASV10059     2.069924e-03  2.168464e-03  2.271673e-03  2.379766e-03
## ASV10263    -4.363038e-03 -4.550107e-03 -4.744286e-03 -4.945769e-03
## ASV1088      5.112308e-03  5.344344e-03  5.586464e-03  5.839074e-03
## ASV1101      6.230955e-03  6.497088e-03  6.773244e-03  7.059689e-03
## ASV1183      1.670109e-03  1.744998e-03  1.823047e-03  1.904370e-03
## ASV11956     1.571666e-03  1.635191e-03  1.700801e-03  1.768526e-03
## ASV12774     7.175092e-05  7.157751e-05  7.109653e-05  7.027113e-05
## ASV1321      7.446288e-03  7.790858e-03  8.150913e-03  8.527108e-03
## ASV13793    -3.008025e-03 -3.136975e-03 -3.270824e-03 -3.409705e-03
## ASV14482     1.845191e-04  1.913753e-04  1.984153e-04  2.056397e-04
## ASV15483     1.259968e-03  1.317514e-03  1.377575e-03  1.440250e-03
## ASV2062      5.802619e-03  6.057007e-03  6.321616e-03  6.596781e-03
## ASV2132      4.789381e-03  5.007367e-03  5.234819e-03  5.472110e-03
## ASV2413      4.465356e-03  4.657834e-03  4.857757e-03  5.065344e-03
## ASV2490      1.363807e-02  1.420891e-02  1.480029e-02  1.541266e-02
## ASV2594      1.739587e-03  1.817971e-03  1.899723e-03  1.984978e-03
## ASV2822     -7.940651e-03 -8.281295e-03 -8.634905e-03 -9.001835e-03
## ASV2863      8.420928e-03  8.778091e-03  9.148557e-03  9.532674e-03
## ASV2910      3.089364e-03  3.221581e-03  3.358816e-03  3.501205e-03
## ASV2980      3.473474e-03  3.626236e-03  3.785167e-03  3.950470e-03
## ASV3307      6.316038e-03  6.586835e-03  6.867925e-03  7.159589e-03
## ASV3474      4.278483e-03  4.478724e-03  4.688152e-03  4.907170e-03
## ASV3502      4.432383e-03  4.630291e-03  4.836470e-03  5.051219e-03
## ASV4236      6.398219e-03  6.663699e-03  6.938477e-03  7.222732e-03
## ASV4842     -7.100442e-04 -7.429085e-04 -7.771960e-04 -8.129550e-04
## ASV4894     -3.009365e-03 -3.138451e-03 -3.272450e-03 -3.411495e-03
## ASV5290      2.427316e-03  2.537290e-03  2.651991e-03  2.771598e-03
## ASV5501      1.478135e-03  1.544295e-03  1.613265e-03  1.685153e-03
## ASV5795      1.632877e-03  1.707152e-03  1.784649e-03  1.865493e-03
## ASV5987     -8.406854e-03 -8.767575e-03 -9.142037e-03 -9.530617e-03
## ASV6267     -9.470912e-03 -9.877177e-03 -1.029891e-02 -1.073653e-02
## ASV6862      3.778563e-03  3.937018e-03  4.101213e-03  4.271283e-03
## ASV7145      1.659266e-03  1.727518e-03  1.798158e-03  1.871240e-03
## ASV7673     -3.009122e-03 -3.138193e-03 -3.272175e-03 -3.411205e-03
## ASV7789      1.557692e-03  1.635308e-03  1.716900e-03  1.802678e-03
## ASV7809      1.264538e-04  1.359198e-04  1.461160e-04  1.570968e-04
## ASV8002     -3.800345e-03 -3.963360e-03 -4.132582e-03 -4.308180e-03
## ASV8205      1.613569e-03  1.686395e-03  1.762338e-03  1.841519e-03
## ASV9155     -9.592601e-04 -9.992632e-04 -1.040682e-03 -1.083546e-03
## ASV9221      4.343738e-04  4.602498e-04  4.877912e-04  5.171098e-04
## ASV9311     -6.095906e-03 -6.357368e-03 -6.628785e-03 -6.910429e-03
## ASV9557     -4.165247e-03 -4.343851e-03 -4.529250e-03 -4.721631e-03
## ASV9936     -8.398081e-03 -8.758086e-03 -9.131779e-03 -9.519536e-03
## ASV1445      5.174616e-03  5.408278e-03  5.651929e-03  5.905948e-03
## ASV4232      1.987970e-03  2.082806e-03  2.182181e-03  2.286314e-03
## ASV6479      7.495585e-04  7.919481e-04  8.369082e-04  8.846023e-04
## ASV0142     -3.612680e-03 -3.766278e-03 -3.925617e-03 -4.090846e-03
## ASV0378      1.693161e-03  1.773795e-03  1.858245e-03  1.946689e-03
## ASV1122      5.019719e-03  5.248268e-03  5.486757e-03  5.735577e-03
## ASV0123     -3.188270e-03 -3.323487e-03 -3.463726e-03 -3.609115e-03
## ASV2064      1.608549e-03  1.672863e-03  1.739189e-03  1.807538e-03
## ASV4459     -2.187435e-04 -2.264410e-04 -2.342916e-04 -2.422886e-04
## ASV0448      1.354510e-03  1.419106e-03  1.486764e-03  1.557628e-03
## ASV0397      2.930081e-03  3.059963e-03  3.195182e-03  3.335923e-03
## ASV0485      3.391083e-03  3.539038e-03  3.692875e-03  3.852779e-03
## ASV1566      5.012037e-03  5.233430e-03  5.463848e-03  5.703594e-03
## ASV1365      4.296483e-03  4.488961e-03  4.689509e-03  4.898416e-03
## ASV1065      6.101817e-03  6.374563e-03  6.658722e-03  6.954707e-03
## ASV0722     -3.226854e-04 -3.378498e-04 -3.537253e-04 -3.703458e-04
## ASV12660    -3.450950e-03 -3.596630e-03 -3.747679e-03 -3.904234e-03
## ASV0223      9.381404e-04  9.793204e-04  1.022165e-03  1.066730e-03
## ASV0229      1.446784e-03  1.512877e-03  1.581870e-03  1.653881e-03
## ASV0877      5.847553e-04  6.075598e-04  6.309872e-04  6.550260e-04
## ASV0983      3.359686e-03  3.505145e-03  3.656270e-03  3.813229e-03
## ASV0626      4.045507e-04  4.292434e-04  4.555381e-04  4.835390e-04
## ASV4146      1.640773e-04  1.708560e-04  1.778326e-04  1.850012e-04
## ASV4175     -4.191527e-03 -4.381704e-03 -4.580088e-03 -4.786996e-03
## ASV2082     -1.964734e-03 -2.067404e-03 -2.175740e-03 -2.290071e-03
## ASV2272      1.992813e-03  2.082767e-03  2.176581e-03  2.274406e-03
## ASV2245     -2.998835e-03 -3.135793e-03 -3.278735e-03 -3.427898e-03
## ASV0590     -1.874710e-03 -1.976204e-03 -2.083541e-03 -2.197075e-03
## ASV0217      2.115432e-04  2.306212e-04  2.513407e-04  2.738322e-04
## ASV0416      2.196656e-03  2.283187e-03  2.372312e-03  2.464035e-03
## ASV1056      2.913766e-03  3.049203e-03  3.190762e-03  3.338700e-03
## ASV7777     -4.072350e-03 -4.255965e-03 -4.447427e-03 -4.647037e-03
## ASV0455      7.288342e-04  7.613245e-04  7.951633e-04  8.303976e-04
## ASV0604      1.926027e-03  2.016877e-03  2.111945e-03  2.211418e-03
## ASV6100     -2.817834e-03 -2.946918e-03 -3.081703e-03 -3.222422e-03
## ASV11359    -6.032034e-03 -6.303838e-03 -6.587198e-03 -6.882544e-03
## ASV6604      8.456559e-04  8.853236e-04  9.268160e-04  9.702130e-04
## ASV5004     -2.140335e-03 -2.235935e-03 -2.335539e-03 -2.439294e-03
## ASV1483     -9.197810e-04 -9.604752e-04 -1.002834e-03 -1.046915e-03
## ASV9773     -2.722353e-03 -2.845960e-03 -2.974922e-03 -3.109450e-03
## ASV4059      4.881548e-05  5.832521e-05  6.888372e-05  8.058513e-05
## ASV1193      3.270311e-03  3.415531e-03  3.566741e-03  3.724153e-03
## ASV4610     -4.566103e-04 -4.671292e-04 -4.772655e-04 -4.869413e-04
## ASV0742     -2.611569e-04 -2.644736e-04 -2.672066e-04 -2.692752e-04
## ASV1502     -1.789165e-04 -1.921836e-04 -2.064695e-04 -2.218501e-04
## ASV0195      6.014039e-05  5.964522e-05  5.885784e-05  5.774559e-05
## ASV1213      2.256281e-03  2.348400e-03  2.443615e-03  2.541973e-03
## ASV1648     -2.529257e-03 -2.644885e-03 -2.765606e-03 -2.891629e-03
## ASV6984     -2.367356e-03 -2.475754e-03 -2.588946e-03 -2.707130e-03
## ASV0396     -1.119402e-04 -1.134374e-04 -1.147070e-04 -1.157187e-04
## ASV4297      3.292557e-03  3.430344e-03  3.573069e-03  3.720841e-03
## ASV2622      5.143123e-03  5.364502e-03  5.594403e-03  5.833072e-03
## ASV3512      2.086861e-03  2.191025e-03  2.300551e-03  2.415727e-03
## ASV2411      3.581871e-03  3.749111e-03  3.923993e-03  4.106850e-03
## ASV2291     -1.630329e-03 -1.720123e-03 -1.815183e-03 -1.915828e-03
## ASV0807      4.817456e-03  5.031474e-03  5.254316e-03  5.486288e-03
## ASV1292      1.129348e-03  1.173907e-03  1.219819e-03  1.267090e-03
## ASV1035      4.367717e-03  4.553615e-03  4.746516e-03  4.946613e-03
## ASV0070      5.952596e-05  6.572953e-05  7.251387e-05  7.992857e-05
## ASV0255      4.067842e-04  4.228559e-04  4.394009e-04  4.564172e-04
## ASV0057     -1.190019e-03 -1.238651e-03 -1.288915e-03 -1.340832e-03
## ASV0077     -2.443665e-04 -2.529975e-04 -2.617872e-04 -2.707239e-04
## ASV0625      2.507443e-03  2.612823e-03  2.722026e-03  2.835140e-03
## ASV2464      1.703759e-02  1.775041e-02  1.848899e-02  1.925396e-02
## ASV1315      4.675082e-03  4.894702e-03  5.124470e-03  5.364836e-03
## ASV2673      4.012381e-03  4.201233e-03  4.398845e-03  4.605607e-03
## ASV2161      1.694935e-03  1.774442e-03  1.857623e-03  1.944643e-03
## ASV0337     -9.622744e-04 -1.006084e-03 -1.051796e-03 -1.099487e-03
## ASV7680     -6.287653e-03 -6.575171e-03 -6.875307e-03 -7.188571e-03
## ASV0611      3.513938e-03  3.675012e-03  3.843200e-03  4.018793e-03
## ASV3118     -3.684223e-03 -3.858686e-03 -4.041322e-03 -4.232503e-03
## ASV1284      1.147498e-03  1.175449e-03  1.202478e-03  1.228368e-03
## ASV0889      2.617930e-03  2.731690e-03  2.849942e-03  2.972828e-03
## ASV4649     -1.323850e-03 -1.383288e-03 -1.445241e-03 -1.509803e-03
## ASV1108     -2.770910e-03 -2.904442e-03 -3.044445e-03 -3.191230e-03
## ASV0738      1.564093e-03  1.644602e-03  1.729442e-03  1.818855e-03
## ASV0473     -3.304721e-04 -3.493177e-04 -3.692900e-04 -3.904556e-04
## ASV0598     -8.113993e-04 -8.550571e-04 -9.012216e-04 -9.500457e-04
## ASV0429      1.930904e-03  2.012814e-03  2.097747e-03  2.185776e-03
## ASV1549      3.704312e-03  3.879001e-03  4.061823e-03  4.253143e-03
## ASV1203      2.851040e-03  2.975464e-03  3.104825e-03  3.239276e-03
## ASV4532      1.127329e-04  1.161725e-04  1.196310e-04  1.231004e-04
## ASV0274      5.164874e-04  5.420330e-04  5.688540e-04  5.970123e-04
## ASV0163     -2.175581e-03 -2.266598e-03 -2.360893e-03 -2.458542e-03
## ASV1298      2.286589e-04  2.368679e-04  2.452720e-04  2.538701e-04
## ASV9424     -4.884164e-03 -5.109083e-03 -5.344036e-03 -5.589444e-03
## ASV0412      4.934428e-03  5.148057e-03  5.370029e-03  5.600594e-03
## ASV0284      9.961959e-04  1.033929e-03  1.072640e-03  1.112314e-03
## ASV0620     -1.070060e-03 -1.125128e-03 -1.183146e-03 -1.244277e-03
## ASV0153     -4.951662e-03 -5.184997e-03 -5.429166e-03 -5.684653e-03
## ASV0498      1.731083e-03  1.810225e-03  1.892814e-03  1.978985e-03
## ASV0097      9.726672e-04  1.018508e-03  1.066482e-03  1.116685e-03
## ASV0104     -6.738750e-03 -7.036196e-03 -7.345732e-03 -7.667763e-03
## ASV1282      2.293394e-03  2.390013e-03  2.490124e-03  2.593804e-03
## ASV3883     -1.914223e-03 -2.008398e-03 -2.107268e-03 -2.211067e-03
## ASV0801      9.228608e-04  9.650210e-04  1.009024e-03  1.054945e-03
## ASV1611     -4.394863e-03 -4.599580e-03 -4.813616e-03 -5.037376e-03
## ASV0227     -8.333254e-04 -8.778949e-04 -9.249740e-04 -9.747086e-04
## ASV0833      1.482910e-03  1.550264e-03  1.620523e-03  1.693800e-03
## ASV0718      6.623394e-03  6.922859e-03  7.235178e-03  7.560846e-03
## ASV1139      7.903652e-04  8.167179e-04  8.433645e-04  8.702437e-04
## ASV0766     -9.530410e-04 -1.000074e-03 -1.049457e-03 -1.101309e-03
## ASV2091      5.267860e-03  5.489518e-03  5.719226e-03  5.957171e-03
## ASV1238     -4.957766e-03 -5.186837e-03 -5.426224e-03 -5.676376e-03
## ASV9193     -5.270721e-04 -5.589344e-04 -5.928946e-04 -6.290986e-04
## ASV0290      6.634620e-04  6.879127e-04  7.129481e-04  7.385549e-04
## ASV0231      1.942040e-03  2.026030e-03  2.113284e-03  2.203896e-03
## ASV0185      1.198005e-03  1.259379e-03  1.324034e-03  1.392150e-03
## ASV2330      2.194545e-03  2.284904e-03  2.378365e-03  2.474984e-03
## ASV3119     -1.081708e-03 -1.136670e-03 -1.194529e-03 -1.255440e-03
## ASV2368     -2.565385e-03 -2.686912e-03 -2.814175e-03 -2.947443e-03
## ASV0122     -1.211761e-03 -1.264871e-03 -1.320112e-03 -1.377555e-03
## ASV1044      3.167066e-03  3.314682e-03  3.469028e-03  3.630397e-03
## ASV0160     -1.278751e-03 -1.331600e-03 -1.386286e-03 -1.442845e-03
## ASV0326      3.479793e-04  3.638048e-04  3.803099e-04  3.975198e-04
## ASV1388      6.295350e-03  6.572497e-03  6.860849e-03  7.160772e-03
## ASV0792      4.629708e-03  4.827527e-03  5.032813e-03  5.245767e-03
## ASV0036     -1.485766e-03 -1.555812e-03 -1.629107e-03 -1.705795e-03
## ASV2125      4.511586e-03  4.711858e-03  4.920376e-03  5.137426e-03
## ASV1075     -6.809499e-05 -7.117903e-05 -7.440455e-05 -7.777901e-05
## ASV0390      2.453703e-03  2.569518e-03  2.690753e-03  2.817654e-03
## ASV3790     -3.448159e-03 -3.605630e-03 -3.769998e-03 -3.941541e-03
## ASV1535     -1.027551e-03 -1.079289e-03 -1.133714e-03 -1.190970e-03
## ASV0263      4.201120e-03  4.389760e-03  4.586375e-03  4.791259e-03
## ASV0675      6.368218e-03  6.662277e-03  6.969495e-03  7.290426e-03
## ASV3348      5.264631e-04  5.522547e-04  5.793250e-04  6.077371e-04
## ASV0058     -1.859722e-03 -1.941269e-03 -2.026082e-03 -2.114268e-03
## ASV4142      2.585705e-03  2.695628e-03  2.809631e-03  2.927814e-03
## ASV0059     -1.494100e-03 -1.559023e-03 -1.626494e-03 -1.696589e-03
## ASV0013     -2.679975e-03 -2.799992e-03 -2.925050e-03 -3.055333e-03
## ASV0033     -1.289780e-03 -1.350342e-03 -1.413694e-03 -1.479959e-03
## ASV4354     -1.580257e-03 -1.651356e-03 -1.725498e-03 -1.802801e-03
## ASV0022     -1.088767e-03 -1.139838e-03 -1.193261e-03 -1.249137e-03
## ASV0134     -1.048971e-03 -1.100142e-03 -1.153840e-03 -1.210192e-03
## ASV0415      1.769381e-04  1.867157e-04  1.970535e-04  2.079827e-04
## ASV10103    -6.018278e-03 -6.296337e-03 -6.586853e-03 -6.890349e-03
## ASV1613      4.390647e-03  4.578402e-03  4.773239e-03  4.975344e-03
## ASV0135     -5.569558e-04 -5.796505e-04 -6.030980e-04 -6.273083e-04
## ASV0469     -5.697114e-03 -5.945470e-03 -6.203693e-03 -6.472096e-03
## ASV0471      3.491537e-03  3.647352e-03  3.809665e-03  3.978710e-03
## ASV0451     -6.139383e-04 -6.478194e-04 -6.836902e-04 -7.216723e-04
## ASV0747      1.996544e-03  2.087082e-03  2.181518e-03  2.280000e-03
## ASV1314     -2.032799e-03 -2.129272e-03 -2.230304e-03 -2.336108e-03
## ASV0425     -6.999721e-03 -7.296615e-03 -7.604526e-03 -7.923731e-03
## ASV0559     -1.753869e-03 -1.831858e-03 -1.913112e-03 -1.997757e-03
## ASV0148     -3.694833e-04 -3.815947e-04 -3.938120e-04 -4.061029e-04
## ASV0129      4.651406e-04  4.943744e-04  5.256027e-04  5.589674e-04
## ASV1072      4.528664e-04  4.702210e-04  4.880352e-04  5.063009e-04
## ASV2390      3.560879e-03  3.707803e-03  3.859762e-03  4.016837e-03
## ASV0548      2.399807e-03  2.506467e-03  2.617533e-03  2.733156e-03
## ASV0168     -1.224035e-03 -1.277224e-03 -1.332505e-03 -1.389944e-03
## ASV0066     -1.382901e-03 -1.443566e-03 -1.506660e-03 -1.572259e-03
## ASV0468     -7.381730e-04 -7.714708e-04 -8.061936e-04 -8.423963e-04
## ASV0172     -3.993387e-04 -4.145066e-04 -4.300662e-04 -4.460101e-04
## ASV0236     -9.023003e-06  1.242705e-06  1.289326e-05  2.606228e-05
## ASV0250      2.023376e-03  2.123588e-03  2.228889e-03  2.339545e-03
## ASV0338      9.447460e-04  9.891437e-04  1.035568e-03  1.084103e-03
## ASV0450     -1.894922e-04 -2.003523e-04 -2.118811e-04 -2.241218e-04
## ASV0377      1.725844e-03  1.801301e-03  1.879764e-03  1.961325e-03
## ASV1022     -7.077945e-05 -7.342652e-05 -7.612613e-05 -7.887333e-05
## ASV6174     -4.563455e-05 -4.889598e-05 -5.241559e-05 -5.621485e-05
## ASV0786     -2.708082e-04 -2.872961e-04 -3.048479e-04 -3.235324e-04
## ASV0053     -1.883238e-03 -1.968081e-03 -2.056530e-03 -2.148720e-03
## ASV0697     -1.128647e-03 -1.176957e-03 -1.227108e-03 -1.279152e-03
## ASV0785      2.391345e-03  2.496009e-03  2.604851e-03  2.718006e-03
## ASV1967     -2.369416e-03 -2.472196e-03 -2.579027e-03 -2.690036e-03
## ASV0385      8.207040e-04  8.598319e-04  9.008025e-04  9.436983e-04
## ASV0295      1.640376e-04  1.747187e-04  1.861515e-04  1.983909e-04
## ASV0072     -1.848655e-03 -1.928060e-03 -2.010490e-03 -2.096026e-03
## ASV0157     -2.062241e-04 -2.104405e-04 -2.143738e-04 -2.179718e-04
## ASV0501      4.071492e-03  4.255707e-03  4.447820e-03  4.648131e-03
## ASV10729    -5.130422e-03 -5.364646e-03 -5.609116e-03 -5.864240e-03
## ASV1470      2.537249e-03  2.641123e-03  2.748495e-03  2.859418e-03
## ASV0050     -4.378566e-03 -4.570871e-03 -4.770906e-03 -4.978924e-03
## ASV0411     -1.006587e-03 -1.053648e-03 -1.102864e-03 -1.154332e-03
## ASV0549      1.611220e-03  1.685505e-03  1.763099e-03  1.844141e-03
## ASV0184      5.314766e-04  5.549284e-04  5.793448e-04  6.047608e-04
## ASV0705      1.043680e-03  1.088486e-03  1.134994e-03  1.183249e-03
## ASV1715      2.236775e-03  2.337347e-03  2.442178e-03  2.551426e-03
## ASV0603      3.528842e-04  3.694608e-04  3.868175e-04  4.049922e-04
## ASV0826      3.759192e-03  3.925587e-03  4.098804e-03  4.279077e-03
## ASV0034     -1.195450e-03 -1.247015e-03 -1.300567e-03 -1.356163e-03
## ASV0838      7.576888e-04  7.798126e-04  8.017662e-04  8.234408e-04
## ASV0614     -1.028617e-03 -1.074058e-03 -1.121357e-03 -1.170577e-03
## ASV0014     -2.731187e-03 -2.852603e-03 -2.979036e-03 -3.110662e-03
## ASV0585      2.463717e-04  2.485811e-04  2.500996e-04  2.508342e-04
## ASV0016     -2.853074e-03 -2.979903e-03 -3.111973e-03 -3.249467e-03
## ASV5394     -2.150313e-03 -2.247661e-03 -2.349190e-03 -2.455059e-03
## ASV0666      4.612679e-03  4.809401e-03  5.013523e-03  5.225240e-03
## ASV2085      9.819321e-04  1.011126e-03  1.040246e-03  1.069179e-03
## ASV0003     -1.944784e-03 -2.031128e-03 -2.121031e-03 -2.214617e-03
## ASV0346      9.966086e-04  1.043788e-03  1.093165e-03  1.144835e-03
## ASV0267      1.048376e-05  1.388280e-05  1.768652e-05  2.193209e-05
## ASV0353      1.575528e-03  1.648821e-03  1.725439e-03  1.805526e-03
## ASV2419      4.173483e-03  4.356754e-03  4.547407e-03  4.745683e-03
## ASV0447      2.312679e-03  2.420657e-03  2.533557e-03  2.651591e-03
## ASV0654      3.380560e-03  3.531191e-03  3.688073e-03  3.851426e-03
## ASV0151      4.733731e-04  4.980283e-04  5.240357e-04  5.514732e-04
## ASV0065     -1.303243e-03 -1.360525e-03 -1.420116e-03 -1.482092e-03
## ASV0527      3.211267e-03  3.353502e-03  3.501573e-03  3.655683e-03
## ASV4055     -5.249019e-04 -5.509389e-04 -5.783173e-04 -6.071107e-04
## ASV0166     -1.596619e-03 -1.664687e-03 -1.735311e-03 -1.808558e-03
## ASV0417     -6.424599e-04 -6.681110e-04 -6.945632e-04 -7.218219e-04
## ASV0078     -9.486711e-04 -9.895074e-04 -1.031906e-03 -1.075908e-03
## ASV0322     -1.570563e-04 -1.610445e-04 -1.648922e-04 -1.685620e-04
## ASV0156     -2.293983e-03 -2.398778e-03 -2.508173e-03 -2.622354e-03
## ASV0648     -4.990562e-03 -5.219953e-03 -5.459516e-03 -5.709668e-03
## ASV0407     -3.781273e-04 -3.961470e-04 -4.150256e-04 -4.348039e-04
## ASV2030     -8.191850e-04 -8.550762e-04 -8.924612e-04 -9.314006e-04
## ASV0300      6.011934e-04  6.296914e-04  6.595253e-04  6.907555e-04
## ASV1150      1.401111e-04  1.475288e-04  1.553565e-04  1.636174e-04
## ASV0958      1.859824e-03  1.948402e-03  2.041190e-03  2.138385e-03
## ASV0216     -2.007578e-03 -2.095268e-03 -2.186479e-03 -2.281327e-03
## ASV0446      3.075499e-03  3.216826e-03  3.364403e-03  3.518482e-03
## ASV0367     -2.006074e-03 -2.096861e-03 -2.191550e-03 -2.290291e-03
## ASV0200     -1.192532e-03 -1.246365e-03 -1.302496e-03 -1.361012e-03
## ASV0334     -6.134293e-04 -6.358662e-04 -6.588198e-04 -6.822750e-04
## ASV1311      7.545691e-04  7.840648e-04  8.144142e-04  8.456143e-04
## ASV0458      1.109917e-03  1.152509e-03  1.196279e-03  1.241218e-03
## ASV1371      1.939600e-04  2.036465e-04  2.138210e-04  2.245071e-04
## ASV0418      2.610501e-03  2.721019e-03  2.835627e-03  2.954430e-03
## ASV0004      3.775639e-04  3.934040e-04  4.098163e-04  4.268139e-04
## ASV1943      7.040375e-03  7.305878e-03  7.578494e-03  7.858181e-03
## ASV1495     -5.834900e-04 -6.179349e-04 -6.545803e-04 -6.935737e-04
## ASV0901     -2.269904e-03 -2.375298e-03 -2.485473e-03 -2.600635e-03
## ASV0628      1.163651e-03  1.210932e-03  1.259764e-03  1.310165e-03
## ASV0400      7.173108e-04  7.479743e-04  7.797874e-04  8.127787e-04
## ASV0116     -6.668512e-04 -6.977053e-04 -7.299478e-04 -7.636378e-04
## ASV0788      5.900624e-03  6.174603e-03  6.460997e-03  6.760340e-03
## ASV0117      4.399817e-04  4.612128e-04  4.834724e-04  5.068099e-04
## ASV3137     -1.350817e-04 -1.408784e-04 -1.468957e-04 -1.531398e-04
## ASV0001      4.044679e-04  4.212845e-04  4.386932e-04  4.567060e-04
## ASV1651      1.156996e-03  1.205836e-03  1.256468e-03  1.308936e-03
## ASV1692      4.910205e-03  5.137536e-03  5.375097e-03  5.623323e-03
## ASV0660      1.683382e-03  1.750506e-03  1.819696e-03  1.890960e-03
## ASV0508      8.357796e-05  8.678157e-05  9.007428e-05  9.345567e-05
## ASV1660     -1.012180e-03 -1.062505e-03 -1.115374e-03 -1.170916e-03
## ASV0233      1.504906e-03  1.572769e-03  1.643528e-03  1.717292e-03
## ASV1343     -2.792935e-03 -2.921718e-03 -3.056255e-03 -3.196788e-03
## ASV0209      1.353867e-03  1.410340e-03  1.468819e-03  1.529345e-03
## ASV0193     -1.585153e-03 -1.651976e-03 -1.721233e-03 -1.792978e-03
## ASV0357      6.481867e-04  6.819244e-04  7.175203e-04  7.550835e-04
## ASV0198      1.215234e-03  1.268323e-03  1.323529e-03  1.380921e-03
## ASV0007      3.549052e-04  3.693145e-04  3.841985e-04  3.995635e-04
## ASV1772     -5.220782e-04 -5.422085e-04 -5.628599e-04 -5.840178e-04
## ASV0009      2.912838e-04  3.027979e-04  3.146612e-04  3.268752e-04
## ASV0006     -3.361629e-04 -3.522761e-04 -3.691616e-04 -3.868558e-04
## ASV0011     -1.149680e-03 -1.202342e-03 -1.257322e-03 -1.314716e-03
## ASV0015      2.200595e-04  2.287398e-04  2.376805e-04  2.468823e-04
## ASV0017      2.480874e-04  2.579058e-04  2.680237e-04  2.784423e-04
## ASV0235     -1.064790e-03 -1.113938e-03 -1.165279e-03 -1.218904e-03
## ASV0382      8.330195e-04  8.713282e-04  9.113131e-04  9.530375e-04
## ASV2357      3.461703e-03  3.620031e-03  3.785320e-03  3.957852e-03
## ASV0567     -6.732562e-04 -7.045101e-04 -7.371918e-04 -7.713658e-04
## ASV0165      5.774238e-04  6.037970e-04  6.313216e-04  6.600433e-04
## ASV0005      8.307962e-04  8.676696e-04  9.060590e-04  9.460165e-04
## ASV0384     -7.416790e-05 -7.491814e-05 -7.546414e-05 -7.577698e-05
## ASV0002      1.536136e-04  1.601560e-04  1.669460e-04  1.739905e-04
## ASV3017      4.341165e-03  4.524703e-03  4.714983e-03  4.912167e-03
## ASV0091     -1.108772e-04 -1.157165e-04 -1.207535e-04 -1.259960e-04
## ASV0186     -1.678332e-03 -1.753397e-03 -1.831599e-03 -1.913048e-03
## ASV0370      8.836867e-04  9.222074e-04  9.622486e-04  1.003857e-03
## ASV0018      1.065647e-03  1.113154e-03  1.162634e-03  1.214156e-03
## ASV1377      1.056343e-02  1.101570e-02  1.148512e-02  1.197217e-02
## ASV0019      1.118383e-03  1.168308e-03  1.220313e-03  1.274472e-03
## ASV0023     -7.067232e-04 -7.394485e-04 -7.736436e-04 -8.093700e-04
## ASV2194      1.141435e-03  1.195171e-03  1.251412e-03  1.310272e-03
## ASV1155      4.416331e-03  4.605281e-03  4.801489e-03  5.005172e-03
## ASV0510     -1.161543e-03 -1.207646e-03 -1.255162e-03 -1.304098e-03
## ASV2371     -2.659785e-03 -2.773562e-03 -2.891687e-03 -3.014286e-03
## ASV0024     -8.789378e-04 -9.194726e-04 -9.618141e-04 -1.006037e-03
## ASV2452      2.639284e-03  2.746830e-03  2.857938e-03  2.972653e-03
## ASV2332     -7.665097e-03 -7.997209e-03 -8.342402e-03 -8.701090e-03
## ASV2591      2.110095e-03  2.217219e-03  2.329854e-03  2.448272e-03
## ASV0521      1.784930e-03  1.867142e-03  1.953016e-03  2.042703e-03
## ASV5542      1.708829e-03  1.787423e-03  1.869471e-03  1.955110e-03
## ASV0336     -2.335645e-04 -2.471215e-04 -2.615167e-04 -2.768030e-04
## ASV10102     3.155296e-03  3.300281e-03  3.451668e-03  3.609714e-03
## ASV16823    -4.729152e-03 -4.924857e-03 -5.127470e-03 -5.337144e-03
## ASV3104      2.446346e-02  2.547556e-02  2.652337e-02  2.760767e-02
## ASV0781      3.485684e-03  3.640748e-03  3.802236e-03  3.970375e-03
## ASV10899     2.140473e-03  2.250371e-03  2.366117e-03  2.488030e-03
## ASV11222    -8.320801e-03 -8.665019e-03 -9.021380e-03 -9.390151e-03
## ASV11327    -7.468717e-03 -7.777606e-03 -8.097385e-03 -8.428294e-03
## ASV12458    -8.316587e-03 -8.660453e-03 -9.016436e-03 -9.384799e-03
## ASV1636      4.755817e-03  4.961081e-03  5.174281e-03  5.395647e-03
## ASV1890     -3.772689e-03 -3.920554e-03 -4.072926e-03 -4.229842e-03
## ASV2898      6.379397e-03  6.655220e-03  6.941763e-03  7.239344e-03
## ASV8328      9.043586e-04  9.677049e-04  1.035694e-03  1.108662e-03
## ASV0709     -7.148663e-03 -7.463404e-03 -7.790845e-03 -8.131397e-03
## ASV0856      6.047602e-03  6.331741e-03  6.628975e-03  6.939877e-03
## ASV0909      1.833557e-03  1.933862e-03  2.039994e-03  2.152306e-03
## ASV0937     -4.250957e-03 -4.446260e-03 -4.650275e-03 -4.863376e-03
## ASV11390    -1.186724e-02 -1.235783e-02 -1.286572e-02 -1.339126e-02
## ASV11966     2.985430e-03  3.129406e-03  3.280302e-03  3.438439e-03
## ASV12990     2.090450e-03  2.179630e-03  2.272137e-03  2.368053e-03
## ASV14797     3.085110e-03  3.214996e-03  3.349614e-03  3.489077e-03
## ASV14904    -1.702826e-02 -1.773220e-02 -1.846093e-02 -1.921500e-02
## ASV15304     1.896354e-03  1.991909e-03  2.092372e-03  2.197992e-03
## ASV16696    -5.882533e-03 -6.125675e-03 -6.377380e-03 -6.637835e-03
## ASV1690      1.028562e-02  1.076984e-02  1.127632e-02  1.180600e-02
## ASV2029      7.018081e-03  7.325747e-03  7.645777e-03  7.978578e-03
## ASV2834      8.883578e-03  9.287592e-03  9.709110e-03  1.014881e-02
## ASV4003      7.431436e-03  7.791325e-03  8.168801e-03  8.564725e-03
## ASV4064      4.226573e-03  4.420553e-03  4.623073e-03  4.834475e-03
## ASV4294      2.624691e-03  2.757122e-03  2.896428e-03  3.042976e-03
## ASV4609      2.369895e-03  2.473065e-03  2.580300e-03  2.691725e-03
## ASV6283     -5.499794e-03 -5.727181e-03 -5.962584e-03 -6.206179e-03
## ASV6491     -7.880920e-03 -8.206670e-03 -8.543896e-03 -8.892851e-03
## ASV7453      3.967135e-03  4.159760e-03  4.361746e-03  4.573537e-03
## ASV7959      1.475377e-03  1.555281e-03  1.639731e-03  1.728992e-03
## ASV8219      6.810063e-02  7.091533e-02  7.382921e-02  7.684444e-02
## ASV8547     -7.053266e-03 -7.344713e-03 -7.646423e-03 -7.958621e-03
## ASV9319      3.168085e-03  3.316312e-03  3.471326e-03  3.633421e-03
## ASV9382     -1.379876e-02 -1.436887e-02 -1.495905e-02 -1.556975e-02
## ASV11516    -9.214133e-03 -9.594728e-03 -9.988714e-03 -1.039638e-02
## ASV14377    -6.651420e-03 -6.926090e-03 -7.210418e-03 -7.504615e-03
## ASV1867      5.287868e-03  5.530636e-03  5.784129e-03  6.048783e-03
## ASV1895      2.581446e-03  2.686540e-03  2.795066e-03  2.907057e-03
## ASV3168      3.272637e-03  3.410166e-03  3.552634e-03  3.700145e-03
## ASV4449      1.826363e-02  1.907541e-02  1.992099e-02  2.080161e-02
## ASV6596      3.906338e-03  4.098618e-03  4.300535e-03  4.512580e-03
## ASV7492     -5.945419e-04 -6.039381e-04 -6.122784e-04 -6.194083e-04
## ASV9854     -1.415305e-03 -1.472578e-03 -1.531787e-03 -1.592972e-03
## ASV6296      1.115812e-01  1.161876e-01  1.209560e-01  1.258898e-01
## ASV4201      6.521349e-04  6.994115e-04  7.502424e-04  8.048893e-04
## ASV0552      3.653736e-03  3.820539e-03  3.994626e-03  4.176287e-03
## ASV3671     -2.409198e-03 -2.514927e-03 -2.625001e-03 -2.739582e-03
## ASV3529     -5.516475e-04 -5.626938e-04 -5.731022e-04 -5.827681e-04
## ASV1060      9.817356e-04  1.028344e-03  1.077164e-03  1.128301e-03
## ASV0239     -1.276916e-03 -1.328669e-03 -1.382129e-03 -1.437320e-03
## ASV5711     -5.873267e-03 -6.127825e-03 -6.392429e-03 -6.667402e-03
## ASV4152     -8.384306e-03 -8.761287e-03 -9.154297e-03 -9.563943e-03
## ASV1461      4.130732e-03  4.299885e-03  4.474757e-03  4.655440e-03
## ASV2877      2.153369e-03  2.242940e-03  2.335656e-03  2.431579e-03
## ASV0012      3.783532e-04  3.952769e-04  4.129118e-04  4.312841e-04
## ASV9823      5.042189e-04  5.208055e-04  5.375308e-04  5.543478e-04
## ASV0008      4.027245e-04  4.205878e-04  4.391893e-04  4.585554e-04
## ASV7832     -4.945283e-03 -5.169447e-03 -5.403353e-03 -5.647394e-03
## ASV1915     -6.169017e-04 -6.431504e-04 -6.704281e-04 -6.987723e-04
## ASV0055     -4.503185e-04 -4.730571e-04 -4.969814e-04 -5.221548e-04
## ASV0032      1.921833e-04  1.991696e-04  2.063097e-04  2.135976e-04
## ASV2977     -6.947567e-03 -7.258386e-03 -7.582277e-03 -7.919724e-03
## ASV0466      5.467627e-03  5.691944e-03  5.923897e-03  6.163613e-03
## ASV3866      3.851627e-03  4.029978e-03  4.216358e-03  4.411109e-03
## ASV0040      1.383518e-03  1.446215e-03  1.511614e-03  1.579821e-03
## ASV0496     -3.759648e-04 -4.012453e-04 -4.283343e-04 -4.573618e-04
## ASV0052      1.162092e-03  1.214842e-03  1.269871e-03  1.327270e-03
## ASV3828     -3.948315e-03 -4.110631e-03 -4.278589e-03 -4.452307e-03
## ASV1930      2.044150e-03  2.131373e-03  2.221849e-03  2.315659e-03
## ASV2126      3.507532e-03  3.661443e-03  3.821550e-03  3.988056e-03
## ASV0793      4.356636e-03  4.557173e-03  4.766618e-03  4.985338e-03
## ASV0299     -8.754332e-05 -9.199862e-05 -9.671764e-05 -1.017208e-04
## ASV0208      3.132383e-03  3.274279e-03  3.422295e-03  3.576670e-03
## ASV0511     -1.252711e-03 -1.303110e-03 -1.355119e-03 -1.408755e-03
## ASV1123     -3.802924e-03 -3.958357e-03 -4.119054e-03 -4.285105e-03
## ASV0099      1.229154e-04  1.295298e-04  1.365315e-04  1.439455e-04
## ASV0752     -2.256808e-03 -2.363694e-03 -2.475581e-03 -2.592695e-03
## ASV0883      3.090985e-03  3.236564e-03  3.388879e-03  3.548228e-03
## ASV0683      4.027314e-03  4.214686e-03  4.410551e-03  4.615273e-03
## ASV4117     -6.369526e-03 -6.657977e-03 -6.958910e-03 -7.272823e-03
## ASV2172      3.915955e-04  4.054528e-04  4.195562e-04  4.338845e-04
## ASV0330     -1.193698e-03 -1.248360e-03 -1.305431e-03 -1.365010e-03
## ASV0728      5.857982e-03  6.119122e-03  6.391098e-03  6.674289e-03
## ASV0499      1.569340e-03  1.642747e-03  1.719521e-03  1.799812e-03
## ASV0120     -2.600156e-03 -2.716413e-03 -2.837523e-03 -2.963659e-03
## ASV1446      1.910967e-03  1.981546e-03  2.053804e-03  2.127698e-03
## ASV17171    -5.018132e-03 -5.241959e-03 -5.475195e-03 -5.718195e-03
## ASV0533      3.839717e-04  4.029058e-04  4.227898e-04  4.436716e-04
## ASV2495     -1.278274e-03 -1.344138e-03 -1.413584e-03 -1.486819e-03
## ASV5582      2.246411e-03  2.333440e-03  2.422945e-03  2.514918e-03
## ASV1488      8.758649e-04  9.129873e-04  9.514683e-04  9.913378e-04
## ASV0682      1.145568e-03  1.199525e-03  1.255986e-03  1.315061e-03
## ASV0068     -1.972356e-03 -2.061110e-03 -2.153621e-03 -2.250026e-03
## ASV1987     -4.981544e-03 -5.218471e-03 -5.466566e-03 -5.726341e-03
## ASV0035     -3.945980e-04 -4.178249e-04 -4.425473e-04 -4.688684e-04
## ASV7192     -3.027109e-03 -3.158542e-03 -3.295158e-03 -3.437117e-03
## ASV0873     -8.898839e-04 -1.024612e-03 -1.172825e-03 -1.335619e-03
## ASV4749     -1.935538e-04 -2.191260e-04 -2.472786e-04 -2.782365e-04
## ASV2174      2.060261e-03  2.141615e-03  2.225422e-03  2.311689e-03
## ASV1476     -2.201404e-03 -2.304988e-03 -2.413408e-03 -2.526889e-03
## ASV0740     -6.244548e-03 -6.537019e-03 -6.842944e-03 -7.162918e-03
## ASV0170     -1.210474e-03 -1.265081e-03 -1.322021e-03 -1.381382e-03
## ASV2466     -5.520254e-03 -5.769682e-03 -6.029842e-03 -6.301156e-03
## ASV1709      1.996936e-03  2.082503e-03  2.171429e-03  2.263831e-03
## ASV6170     -8.692610e-03 -9.094052e-03 -9.513473e-03 -9.951628e-03
## ASV3673      4.283839e-03  4.484362e-03  4.694096e-03  4.913446e-03
## ASV1745     -1.123678e-03 -1.178826e-03 -1.236724e-03 -1.297512e-03
##                                                                    
## (Intercept)  3.505534e-02  3.661815e-02  3.824567e-02  3.994015e-02
## ASV1236      6.792624e-03  7.079326e-03  7.376630e-03  7.684813e-03
## ASV0421      8.683494e-04  9.167376e-04  9.679650e-04  1.022199e-03
## ASV0691     -5.103527e-03 -5.296051e-03 -5.493710e-03 -5.696469e-03
## ASV0899      5.899311e-03  6.149431e-03  6.408788e-03  6.677607e-03
## ASV1004      1.362156e-02  1.419872e-02  1.479730e-02  1.541787e-02
## ASV1041     -5.583745e-03 -5.817608e-03 -6.059804e-03 -6.310501e-03
## ASV1058      8.494867e-03  8.854069e-03  9.226577e-03  9.612737e-03
## ASV12542     3.257624e-03  3.390874e-03  3.528677e-03  3.671120e-03
## ASV1294      7.911766e-03  8.247058e-03  8.594836e-03  8.955430e-03
## ASV13113     2.764178e-03  2.896589e-03  3.035348e-03  3.180755e-03
## ASV1318      7.885287e-03  8.218862e-03  8.564785e-03  8.923372e-03
## ASV2269     -1.362893e-02 -1.420202e-02 -1.479593e-02 -1.541115e-02
## ASV2542      6.838774e-03  7.151441e-03  7.477853e-03  7.818569e-03
## ASV2660     -5.408756e-03 -5.634434e-03 -5.868175e-03 -6.110158e-03
## ASV2737      1.835354e-03  1.907450e-03  1.981764e-03  2.058317e-03
## ASV2840      7.124632e-03  7.410924e-03  7.706422e-03  8.011230e-03
## ASV3053      3.670780e-02  3.821508e-02  3.977435e-02  4.138662e-02
## ASV3077      2.346413e-03  2.443466e-03  2.543943e-03  2.647923e-03
## ASV3134      4.378274e-03  4.583818e-03  4.798871e-03  5.023860e-03
## ASV3140      5.821423e-03  6.080539e-03  6.350392e-03  6.631358e-03
## ASV3579      2.151369e-03  2.258080e-03  2.370189e-03  2.487971e-03
## ASV6119     -3.729050e-03 -3.885812e-03 -4.048266e-03 -4.216544e-03
## ASV7557     -7.575937e-03 -7.894310e-03 -8.224234e-03 -8.565977e-03
## ASV8422      1.875329e-03  1.952635e-03  2.032646e-03  2.115422e-03
## ASV1086     -2.801074e-04 -2.901575e-04 -3.004406e-04 -3.109533e-04
## ASV1310      3.634774e-03  3.788108e-03  3.947070e-03  4.111799e-03
## ASV15750    -4.793906e-04 -4.976868e-04 -5.164723e-04 -5.357409e-04
## ASV16905    -1.557862e-03 -1.623330e-03 -1.691173e-03 -1.761447e-03
## ASV2033      6.900948e-03  7.220346e-03  7.554045e-03  7.902637e-03
## ASV2089      3.286770e-03  3.425101e-03  3.568468e-03  3.716990e-03
## ASV2127      1.068467e-02  1.113578e-02  1.160352e-02  1.208831e-02
## ASV2725      8.482114e-03  8.832273e-03  9.194637e-03  9.569453e-03
## ASV2804     -3.224541e-03 -3.360037e-03 -3.500448e-03 -3.645889e-03
## ASV3075      7.191110e-03  7.508419e-03  7.838793e-03  8.182704e-03
## ASV3327      1.006847e-02  1.052635e-02  1.100406e-02  1.150240e-02
## ASV3342      8.623941e-03  9.012835e-03  9.418335e-03  9.841073e-03
## ASV3532     -9.458968e-03 -9.879103e-03 -1.031667e-02 -1.077228e-02
## ASV3600      4.407380e-03  4.604366e-03  4.809622e-03  5.023453e-03
## ASV4013      8.124876e-03  8.476624e-03  8.842107e-03  9.221741e-03
## ASV4136      8.530173e-03  8.884314e-03  9.251052e-03  9.630673e-03
## ASV4195      3.290609e-02  3.428835e-02  3.572072e-02  3.720437e-02
## ASV4407     -1.271041e-02 -1.324415e-02 -1.379722e-02 -1.437008e-02
## ASV4717      2.146612e-03  2.229330e-03  2.314438e-03  2.401945e-03
## ASV6794      5.199639e-03  5.410605e-03  5.628675e-03  5.853980e-03
## ASV8324     -6.522037e-03 -6.795910e-03 -7.079704e-03 -7.373648e-03
## ASV8981     -1.157939e-04 -1.152558e-04 -1.141905e-04 -1.125357e-04
## ASV9859      2.442847e-03  2.566847e-03  2.697392e-03  2.834840e-03
## ASV0936      6.504619e-03  6.797957e-03  7.103757e-03  7.422480e-03
## ASV12683    -2.166102e-05 -2.416516e-05 -2.688405e-05 -2.983122e-05
## ASV1293      4.226989e-03  4.404136e-03  4.587690e-03  4.777802e-03
## ASV13055    -6.627816e-05 -6.511048e-05 -6.352999e-05 -6.149073e-05
## ASV17063    -3.380809e-03 -3.522621e-03 -3.669559e-03 -3.821740e-03
## ASV2228      2.756365e-03  2.871946e-03  2.991701e-03  3.115726e-03
## ASV2769      4.847533e-04  5.109071e-04  5.385263e-04  5.676924e-04
## ASV2803      2.930555e-03  3.047585e-03  3.168354e-03  3.292906e-03
## ASV2896      2.467391e-03  2.580528e-03  2.698702e-03  2.822131e-03
## ASV3062      3.053044e-03  3.201093e-03  3.356350e-03  3.519162e-03
## ASV3107      4.574660e-03  4.781483e-03  4.997210e-03  5.222188e-03
## ASV3265      6.038973e-03  6.291001e-03  6.552039e-03  6.822287e-03
## ASV3666      5.274137e-05  5.422257e-05  5.567944e-05  5.710264e-05
## ASV4497      2.089821e-03  2.178789e-03  2.271104e-03  2.366854e-03
## ASV6914     -3.436204e-04 -3.617853e-04 -3.809510e-04 -4.011729e-04
## ASV0576     -7.060336e-03 -7.338595e-03 -7.625409e-03 -7.920850e-03
## ASV0673      8.083393e-03  8.431319e-03  8.792642e-03  9.167752e-03
## ASV0772      3.769848e-03  3.934257e-03  4.105219e-03  4.282947e-03
## ASV0862      4.928330e-04  5.287431e-04  5.673217e-04  6.087561e-04
## ASV0898      3.012530e-03  3.153157e-03  3.300160e-03  3.453807e-03
## ASV0910      3.439534e-03  3.596157e-03  3.759604e-03  3.930149e-03
## ASV0964     -2.688158e-03 -2.796136e-03 -2.907600e-03 -3.022592e-03
## ASV10059     2.492971e-03  2.611523e-03  2.735670e-03  2.865667e-03
## ASV10263    -5.154746e-03 -5.371409e-03 -5.595945e-03 -5.828537e-03
## ASV1088      6.102593e-03  6.377455e-03  6.664108e-03  6.963018e-03
## ASV1101      7.356683e-03  7.664487e-03  7.983353e-03  8.313531e-03
## ASV1183      1.989088e-03  2.077324e-03  2.169203e-03  2.264854e-03
## ASV11956     1.838393e-03  1.910426e-03  1.984645e-03  2.061067e-03
## ASV12774     6.906142e-05  6.742433e-05  6.531345e-05  6.267885e-05
## ASV1321      8.920122e-03  9.330656e-03  9.759439e-03  1.020722e-02
## ASV13793    -3.553750e-03 -3.703089e-03 -3.857850e-03 -4.018161e-03
## ASV14482     2.130490e-04  2.206434e-04  2.284233e-04  2.363890e-04
## ASV15483     1.505643e-03  1.573859e-03  1.645006e-03  1.719197e-03
## ASV2062      6.882843e-03  7.180147e-03  7.489043e-03  7.809886e-03
## ASV2132      5.719622e-03  5.977749e-03  6.246897e-03  6.527480e-03
## ASV2413      5.280816e-03  5.504395e-03  5.736302e-03  5.976761e-03
## ASV2490      1.604647e-02  1.670215e-02  1.738014e-02  1.808084e-02
## ASV2594      2.073874e-03  2.166555e-03  2.263170e-03  2.363873e-03
## ASV2822     -9.382437e-03 -9.777059e-03 -1.018605e-02 -1.060974e-02
## ASV2863      9.930786e-03  1.034324e-02  1.077036e-02  1.121249e-02
## ASV2910      3.648885e-03  3.801992e-03  3.960663e-03  4.125030e-03
## ASV2980      4.122351e-03  4.301020e-03  4.486687e-03  4.679567e-03
## ASV3307      7.462104e-03  7.775745e-03  8.100784e-03  8.437489e-03
## ASV3474      5.136196e-03  5.375665e-03  5.626027e-03  5.887750e-03
## ASV3502      5.274843e-03  5.507657e-03  5.749980e-03  6.002141e-03
## ASV4236      7.516636e-03  7.820351e-03  8.134030e-03  8.457810e-03
## ASV4842     -8.502338e-04 -8.890805e-04 -9.295423e-04 -9.716659e-04
## ASV4894     -3.555721e-03 -3.705260e-03 -3.860242e-03 -4.020796e-03
## ASV5290      2.896298e-03  3.026279e-03  3.161736e-03  3.302871e-03
## ASV5501      1.760073e-03  1.838143e-03  1.919485e-03  2.004225e-03
## ASV5795      1.949814e-03  2.037746e-03  2.129425e-03  2.224993e-03
## ASV5987     -9.933688e-03 -1.035162e-02 -1.078479e-02 -1.123355e-02
## ASV6267     -1.119046e-02 -1.166111e-02 -1.214890e-02 -1.265424e-02
## ASV6862      4.447360e-03  4.629576e-03  4.818056e-03  5.012925e-03
## ASV7145      1.946817e-03  2.024942e-03  2.105666e-03  2.189041e-03
## ASV7673     -3.555415e-03 -3.704938e-03 -3.859904e-03 -4.020444e-03
## ASV7789      1.892861e-03  1.987680e-03  2.087380e-03  2.192215e-03
## ASV7809      1.689203e-04  1.816486e-04  1.953474e-04  2.100865e-04
## ASV8002     -4.490324e-03 -4.679181e-03 -4.874919e-03 -5.077700e-03
## ASV8205      1.924061e-03  2.010091e-03  2.099739e-03  2.193141e-03
## ASV9155     -1.127880e-03 -1.173712e-03 -1.221065e-03 -1.269960e-03
## ASV9221      5.483244e-04  5.815618e-04  6.169566e-04  6.546517e-04
## ASV9311     -7.202572e-03 -7.505485e-03 -7.819434e-03 -8.144682e-03
## ASV9557     -4.921178e-03 -5.128076e-03 -5.342506e-03 -5.564647e-03
## ASV9936     -9.921727e-03 -1.033872e-02 -1.077089e-02 -1.121858e-02
## ASV1445      6.170723e-03  6.446655e-03  6.734154e-03  7.033640e-03
## ASV4232      2.395435e-03  2.509787e-03  2.629621e-03  2.755203e-03
## ASV6479      9.352037e-04  9.888966e-04  1.045876e-03  1.106350e-03
## ASV0142     -4.262114e-03 -4.439568e-03 -4.623353e-03 -4.813611e-03
## ASV0378      2.039311e-03  2.136300e-03  2.237857e-03  2.344187e-03
## ASV1122      5.995133e-03  6.265842e-03  6.548132e-03  6.842445e-03
## ASV0123     -3.759781e-03 -3.915848e-03 -4.077441e-03 -4.244678e-03
## ASV2064      1.877919e-03  1.950332e-03  2.024775e-03  2.101236e-03
## ASV4459     -2.504246e-04 -2.586912e-04 -2.670794e-04 -2.755792e-04
## ASV0448      1.631846e-03  1.709571e-03  1.790964e-03  1.876191e-03
## ASV0397      3.482371e-03  3.634719e-03  3.793161e-03  3.957892e-03
## ASV0485      4.018942e-03  4.191554e-03  4.370809e-03  4.556903e-03
## ASV1566      5.952979e-03  6.212316e-03  6.481925e-03  6.762129e-03
## ASV1365      5.115976e-03  5.342491e-03  5.578266e-03  5.823613e-03
## ASV1065      7.262939e-03  7.583849e-03  7.917878e-03  8.265475e-03
## ASV0722     -3.877469e-04 -4.059663e-04 -4.250434e-04 -4.450198e-04
## ASV12660    -4.066426e-03 -4.234389e-03 -4.408252e-03 -4.588141e-03
## ASV0223      1.113073e-03  1.161251e-03  1.211325e-03  1.263355e-03
## ASV0229      1.729031e-03  1.807446e-03  1.889256e-03  1.974593e-03
## ASV0877      6.796606e-04  7.048711e-04  7.306325e-04  7.569146e-04
## ASV0983      3.976191e-03  4.145324e-03  4.320797e-03  4.502779e-03
## ASV0626      5.133567e-04  5.451075e-04  5.789147e-04  6.149079e-04
## ASV4146      1.923542e-04  1.998812e-04  2.075693e-04  2.154026e-04
## ASV4175     -5.002754e-03 -5.227699e-03 -5.462176e-03 -5.706539e-03
## ASV2082     -2.410747e-03 -2.538139e-03 -2.672638e-03 -2.814660e-03
## ASV2272      2.376396e-03  2.482711e-03  2.593517e-03  2.708983e-03
## ASV2245     -3.583527e-03 -3.745874e-03 -3.915197e-03 -4.091764e-03
## ASV0590     -2.317177e-03 -2.444245e-03 -2.578698e-03 -2.720977e-03
## ASV0217      2.982350e-04  3.246979e-04  3.533796e-04  3.844486e-04
## ASV0416      2.558356e-03  2.655263e-03  2.754740e-03  2.856757e-03
## ASV1056      3.493287e-03  3.654800e-03  3.823525e-03  3.999759e-03
## ASV7777     -4.855105e-03 -5.071951e-03 -5.297903e-03 -5.533299e-03
## ASV0455      8.670755e-04  9.052457e-04  9.449579e-04  9.862623e-04
## ASV0604      2.315490e-03  2.424363e-03  2.538248e-03  2.657360e-03
## ASV6100     -3.369320e-03 -3.522648e-03 -3.682667e-03 -3.849647e-03
## ASV11359    -7.190318e-03 -7.510972e-03 -7.844969e-03 -8.192784e-03
## ASV6604      1.015598e-03  1.063056e-03  1.112677e-03  1.164554e-03
## ASV5004     -2.547352e-03 -2.659865e-03 -2.776993e-03 -2.898897e-03
## ASV1483     -1.092775e-03 -1.140474e-03 -1.190071e-03 -1.241626e-03
## ASV9773     -3.249761e-03 -3.396079e-03 -3.548637e-03 -3.707672e-03
## ASV4059      9.353058e-05  1.078286e-04  1.235956e-04  1.409560e-04
## ASV1193      3.887978e-03  4.058435e-03  4.235746e-03  4.420136e-03
## ASV4610     -4.960724e-04 -5.045677e-04 -5.123293e-04 -5.192522e-04
## ASV0742     -2.705923e-04 -2.710637e-04 -2.705882e-04 -2.690569e-04
## ASV1502     -2.384067e-04 -2.562254e-04 -2.753981e-04 -2.960223e-04
## ASV0195      5.627328e-05  5.440310e-05  5.209448e-05  4.930399e-05
## ASV1213      2.643520e-03  2.748295e-03  2.856331e-03  2.967659e-03
## ASV1648     -3.023171e-03 -3.160457e-03 -3.303720e-03 -3.453203e-03
## ASV6984     -2.830514e-03 -2.959313e-03 -3.093749e-03 -3.234054e-03
## ASV0396     -1.164405e-04 -1.168378e-04 -1.168742e-04 -1.165111e-04
## ASV4297      3.873762e-03  4.031933e-03  4.195450e-03  4.364404e-03
## ASV2622      6.080755e-03  6.337697e-03  6.604146e-03  6.880347e-03
## ASV3512      2.536853e-03  2.664248e-03  2.798246e-03  2.939201e-03
## ASV2411      4.298027e-03  4.497884e-03  4.706793e-03  4.925141e-03
## ASV2291     -2.022399e-03 -2.135255e-03 -2.254779e-03 -2.381371e-03
## ASV0807      5.727701e-03  5.978870e-03  6.240115e-03  6.511762e-03
## ASV1292      1.315724e-03  1.365720e-03  1.417073e-03  1.469777e-03
## ASV1035      5.154098e-03  5.369164e-03  5.592002e-03  5.822804e-03
## ASV0070      8.802698e-05  9.686639e-05  1.065083e-04  1.170187e-04
## ASV0255      4.739007e-04  4.918451e-04  5.102417e-04  5.290790e-04
## ASV0057     -1.394426e-03 -1.449715e-03 -1.506714e-03 -1.565435e-03
## ASV0077     -2.797945e-04 -2.889841e-04 -2.982757e-04 -3.076503e-04
## ASV0625      2.952250e-03  3.073441e-03  3.198793e-03  3.328384e-03
## ASV2464      2.004589e-02  2.086540e-02  2.171304e-02  2.258938e-02
## ASV1315      5.616269e-03  5.879257e-03  6.154305e-03  6.441939e-03
## ASV2673      4.821929e-03  5.048234e-03  5.284963e-03  5.532576e-03
## ASV2161      2.035674e-03  2.130895e-03  2.230493e-03  2.334661e-03
## ASV0337     -1.149234e-03 -1.201114e-03 -1.255211e-03 -1.311609e-03
## ASV7680     -7.515486e-03 -7.856594e-03 -8.212455e-03 -8.583645e-03
## ASV0611      4.202095e-03  4.393416e-03  4.593080e-03  4.801421e-03
## ASV3118     -4.432614e-03 -4.642058e-03 -4.861253e-03 -5.090634e-03
## ASV1284      1.252881e-03  1.275755e-03  1.296702e-03  1.315411e-03
## ASV0889      3.100492e-03  3.233080e-03  3.370738e-03  3.513617e-03
## ASV4649     -1.577072e-03 -1.647145e-03 -1.720124e-03 -1.796115e-03
## ASV1108     -3.345125e-03 -3.506472e-03 -3.675630e-03 -3.852974e-03
## ASV0738      1.913097e-03  2.012439e-03  2.117165e-03  2.227577e-03
## ASV0473     -4.128847e-04 -4.366505e-04 -4.618301e-04 -4.885039e-04
## ASV0598     -1.001691e-03 -1.056331e-03 -1.114147e-03 -1.175332e-03
## ASV0429      2.276973e-03  2.371406e-03  2.469141e-03  2.570241e-03
## ASV1549      4.453343e-03  4.662820e-03  4.881988e-03  5.111275e-03
## ASV1203      3.378974e-03  3.524074e-03  3.674736e-03  3.831117e-03
## ASV4532      1.265725e-04  1.300383e-04  1.334883e-04  1.369126e-04
## ASV0274      6.265726e-04  6.576018e-04  6.901697e-04  7.243484e-04
## ASV0163     -2.559620e-03 -2.664199e-03 -2.772351e-03 -2.884144e-03
## ASV1298      2.626606e-04  2.716422e-04  2.808136e-04  2.901740e-04
## ASV9424     -5.845743e-03 -6.113387e-03 -6.392845e-03 -6.684604e-03
## ASV0412      5.840008e-03  6.088523e-03  6.346397e-03  6.613886e-03
## ASV0284      1.152930e-03  1.194459e-03  1.236871e-03  1.280126e-03
## ASV0620     -1.308691e-03 -1.376569e-03 -1.448100e-03 -1.523486e-03
## ASV0153     -5.951960e-03 -6.231612e-03 -6.524152e-03 -6.830145e-03
## ASV0498      2.068872e-03  2.162617e-03  2.260361e-03  2.362250e-03
## ASV0097      1.169219e-03  1.224188e-03  1.281700e-03  1.341869e-03
## ASV0104     -8.002695e-03 -8.350944e-03 -8.712928e-03 -9.089070e-03
## ASV1282      2.701122e-03  2.812146e-03  2.926938e-03  3.045557e-03
## ASV3883     -2.320038e-03 -2.434437e-03 -2.554528e-03 -2.680591e-03
## ASV0801      1.102858e-03  1.152842e-03  1.204978e-03  1.259349e-03
## ASV1611     -5.271281e-03 -5.515766e-03 -5.771285e-03 -6.038306e-03
## ASV0227     -1.027253e-03 -1.082769e-03 -1.141428e-03 -1.203411e-03
## ASV0833      1.770209e-03  1.849867e-03  1.932896e-03  2.019418e-03
## ASV0718      7.900372e-03  8.254279e-03  8.623104e-03  9.007402e-03
## ASV1139      8.972866e-04  9.244160e-04  9.515454e-04  9.785787e-04
## ASV0766     -1.155750e-03 -1.212908e-03 -1.272916e-03 -1.335912e-03
## ASV2091      6.203531e-03  6.458483e-03  6.722193e-03  6.994822e-03
## ASV1238     -5.937756e-03 -6.210847e-03 -6.496153e-03 -6.794197e-03
## ASV9193     -6.677025e-04 -7.088730e-04 -7.527885e-04 -7.996391e-04
## ASV0290      7.647170e-04  7.914158e-04  8.186295e-04  8.463331e-04
## ASV0231      2.297962e-03  2.395578e-03  2.496840e-03  2.601842e-03
## ASV0185      1.463922e-03  1.539551e-03  1.619253e-03  1.703253e-03
## ASV2330      2.574812e-03  2.677898e-03  2.784283e-03  2.894009e-03
## ASV3119     -1.319572e-03 -1.387097e-03 -1.458200e-03 -1.533075e-03
## ASV2368     -3.087000e-03 -3.233139e-03 -3.386169e-03 -3.546416e-03
## ASV0122     -1.437269e-03 -1.499325e-03 -1.563797e-03 -1.630756e-03
## ASV1044      3.799094e-03  3.975435e-03  4.159750e-03  4.352379e-03
## ASV0160     -1.501312e-03 -1.561717e-03 -1.624092e-03 -1.688465e-03
## ASV0326      4.154600e-04  4.341565e-04  4.536357e-04  4.739243e-04
## ASV1388      7.472641e-03  7.796834e-03  8.133732e-03  8.483723e-03
## ASV0792      5.466586e-03  5.695466e-03  5.932601e-03  6.178180e-03
## ASV0036     -1.786026e-03 -1.869954e-03 -1.957742e-03 -2.049555e-03
## ASV2125      5.363296e-03  5.598281e-03  5.842681e-03  6.096799e-03
## ASV1075     -8.131042e-05 -8.500744e-05 -8.887940e-05 -9.293641e-05
## ASV0390      2.950484e-03  3.089512e-03  3.235024e-03  3.387314e-03
## ASV3790     -4.120543e-03 -4.307302e-03 -4.502121e-03 -4.705315e-03
## ASV1535     -1.251207e-03 -1.314583e-03 -1.381265e-03 -1.451427e-03
## ASV0263      5.004716e-03  5.227056e-03  5.458598e-03  5.699666e-03
## ASV0675      7.625641e-03  7.975732e-03  8.341311e-03  8.723013e-03
## ASV3348      6.375571e-04  6.688542e-04  7.017005e-04  7.361714e-04
## ASV0058     -2.205931e-03 -2.301179e-03 -2.400119e-03 -2.502860e-03
## ASV4142      3.050277e-03  3.177116e-03  3.308425e-03  3.444297e-03
## ASV0059     -1.769384e-03 -1.844958e-03 -1.923388e-03 -2.004750e-03
## ASV0013     -3.191028e-03 -3.332328e-03 -3.479429e-03 -3.632531e-03
## ASV0033     -1.549264e-03 -1.621741e-03 -1.697527e-03 -1.776763e-03
## ASV4354     -1.883389e-03 -1.967388e-03 -2.054931e-03 -2.146154e-03
## ASV0022     -1.307575e-03 -1.368685e-03 -1.432584e-03 -1.499391e-03
## ASV0134     -1.269329e-03 -1.331390e-03 -1.396520e-03 -1.464869e-03
## ASV0415      2.195359e-04  2.317471e-04  2.446517e-04  2.582867e-04
## ASV10103    -7.207368e-03 -7.538471e-03 -7.884240e-03 -8.245276e-03
## ASV1613      5.184902e-03  5.402091e-03  5.627091e-03  5.860073e-03
## ASV0135     -6.522902e-04 -6.780510e-04 -7.045967e-04 -7.319314e-04
## ASV0469     -6.750999e-03 -7.040727e-03 -7.341609e-03 -7.653975e-03
## ASV0471      4.154723e-03  4.337950e-03  4.528639e-03  4.727044e-03
## ASV0451     -7.618939e-04 -8.044912e-04 -8.496076e-04 -8.973951e-04
## ASV0747      2.382682e-03  2.489720e-03  2.601278e-03  2.717519e-03
## ASV1314     -2.446907e-03 -2.562934e-03 -2.684433e-03 -2.811658e-03
## ASV0425     -8.254506e-03 -8.597119e-03 -8.951837e-03 -9.318916e-03
## ASV0559     -2.085918e-03 -2.177730e-03 -2.273327e-03 -2.372853e-03
## ASV0148     -4.184310e-04 -4.307556e-04 -4.430312e-04 -4.552073e-04
## ASV0129      5.946200e-04  6.327225e-04  6.734477e-04  7.169803e-04
## ASV1072      5.250076e-04  5.441421e-04  5.636881e-04  5.836259e-04
## ASV2390      4.179103e-03  4.346628e-03  4.519468e-03  4.697670e-03
## ASV0548      2.853493e-03  2.978703e-03  3.108948e-03  3.244391e-03
## ASV0168     -1.449606e-03 -1.511556e-03 -1.575860e-03 -1.642585e-03
## ASV0066     -1.640442e-03 -1.711287e-03 -1.784872e-03 -1.861275e-03
## ASV0468     -8.801354e-04 -9.194692e-04 -9.604577e-04 -1.003163e-03
## ASV0172     -4.623285e-04 -4.790094e-04 -4.960383e-04 -5.133979e-04
## ASV0236      4.089384e-05  5.754311e-05  7.617694e-05  9.697453e-05
## ASV0250      2.455835e-03  2.578052e-03  2.706506e-03  2.841520e-03
## ASV0338      1.134836e-03  1.187855e-03  1.243253e-03  1.301123e-03
## ASV0450     -2.371202e-04 -2.509251e-04 -2.655884e-04 -2.811650e-04
## ASV0377      2.046081e-03  2.134127e-03  2.225561e-03  2.320479e-03
## ASV1022     -8.166224e-05 -8.448584e-05 -8.733594e-05 -9.020300e-05
## ASV6174     -6.031691e-05 -6.474680e-05 -6.953150e-05 -7.470006e-05
## ASV0786     -3.434224e-04 -3.645948e-04 -3.871307e-04 -4.111159e-04
## ASV0053     -2.244790e-03 -2.344880e-03 -2.449136e-03 -2.557707e-03
## ASV0697     -1.333142e-03 -1.389129e-03 -1.447167e-03 -1.507307e-03
## ASV0785      2.835608e-03  2.957793e-03  3.084697e-03  3.216459e-03
## ASV1967     -2.805353e-03 -2.925110e-03 -3.049439e-03 -3.178475e-03
## ASV0385      9.886048e-04  1.035611e-03  1.084807e-03  1.136290e-03
## ASV0295      2.114951e-04  2.255266e-04  2.405522e-04  2.566429e-04
## ASV0072     -2.184749e-03 -2.276740e-03 -2.372076e-03 -2.470836e-03
## ASV0157     -2.211770e-04 -2.239265e-04 -2.261513e-04 -2.277761e-04
## ASV0501      4.856946e-03  5.074581e-03  5.301359e-03  5.537610e-03
## ASV10729    -6.130441e-03 -6.408156e-03 -6.697832e-03 -6.999934e-03
## ASV1470      2.973938e-03  3.092098e-03  3.213931e-03  3.339468e-03
## ASV0050     -5.195176e-03 -5.419918e-03 -5.653408e-03 -5.895907e-03
## ASV0411     -1.208149e-03 -1.264417e-03 -1.323243e-03 -1.384738e-03
## ASV0549      1.928773e-03  2.017140e-03  2.109394e-03  2.205692e-03
## ASV0184      6.312122e-04  6.587359e-04  6.873699e-04  7.171535e-04
## ASV0705      1.233297e-03  1.285181e-03  1.338944e-03  1.394628e-03
## ASV1715      2.665252e-03  2.783822e-03  2.907306e-03  3.035877e-03
## ASV0603      4.240247e-04  4.439573e-04  4.648343e-04  4.867030e-04
## ASV0826      4.466645e-03  4.661752e-03  4.864645e-03  5.075576e-03
## ASV0034     -1.413859e-03 -1.473711e-03 -1.535775e-03 -1.600105e-03
## ASV0838      8.447150e-04  8.654535e-04  8.855064e-04  9.047079e-04
## ASV0614     -1.221783e-03 -1.275040e-03 -1.330417e-03 -1.387981e-03
## ASV0014     -3.247660e-03 -3.390211e-03 -3.538501e-03 -3.692718e-03
## ASV0585      2.506838e-04  2.495391e-04  2.472813e-04  2.437825e-04
## ASV0016     -3.392572e-03 -3.541478e-03 -3.696377e-03 -3.857467e-03
## ASV5394     -2.565435e-03 -2.680484e-03 -2.800381e-03 -2.925303e-03
## ASV0666      5.444748e-03  5.672238e-03  5.907901e-03  6.151923e-03
## ASV2085      1.097799e-03  1.125967e-03  1.153532e-03  1.180326e-03
## ASV0003     -2.312011e-03 -2.413341e-03 -2.518739e-03 -2.628335e-03
## ASV0346      1.198901e-03  1.255465e-03  1.314635e-03  1.376522e-03
## ASV0267      2.665938e-05  3.191109e-05  3.773288e-05  4.417344e-05
## ASV0353      1.889228e-03  1.976700e-03  2.068102e-03  2.163597e-03
## ASV2419      4.951828e-03  5.166089e-03  5.388719e-03  5.619972e-03
## ASV0447      2.774978e-03  2.903947e-03  3.038733e-03  3.179579e-03
## ASV0654      4.021473e-03  4.198442e-03  4.382566e-03  4.574080e-03
## ASV0151      5.804230e-04  6.109721e-04  6.432126e-04  6.772415e-04
## ASV0065     -1.546530e-03 -1.613507e-03 -1.683102e-03 -1.755393e-03
## ASV0527      3.816034e-03  3.982835e-03  4.156299e-03  4.336640e-03
## ASV4055     -6.373973e-04 -6.692600e-04 -7.027867e-04 -7.380709e-04
## ASV0166     -1.884494e-03 -1.963184e-03 -2.044693e-03 -2.129083e-03
## ASV0417     -7.498905e-04 -7.787703e-04 -8.084605e-04 -8.389575e-04
## ASV0078     -1.121557e-03 -1.168895e-03 -1.217960e-03 -1.268795e-03
## ASV0322     -1.720122e-04 -1.751962e-04 -1.780623e-04 -1.805527e-04
## ASV0156     -2.741515e-03 -2.865855e-03 -2.995581e-03 -3.130906e-03
## ASV0648     -5.970842e-03 -6.243486e-03 -6.528061e-03 -6.825046e-03
## ASV0407     -4.555248e-04 -4.772333e-04 -4.999763e-04 -5.238032e-04
## ASV2030     -9.719582e-04 -1.014201e-03 -1.058199e-03 -1.104027e-03
## ASV0300      7.234449e-04  7.576587e-04  7.934647e-04  8.309336e-04
## ASV1150      1.723356e-04  1.815364e-04  1.912467e-04  2.014942e-04
## ASV0958      2.240196e-03  2.346839e-03  2.458540e-03  2.575538e-03
## ASV0216     -2.379936e-03 -2.482429e-03 -2.588933e-03 -2.699579e-03
## ASV0446      3.679325e-03  3.847202e-03  4.022391e-03  4.205180e-03
## ASV0367     -2.393239e-03 -2.500552e-03 -2.612395e-03 -2.728935e-03
## ASV0200     -1.422002e-03 -1.485557e-03 -1.551770e-03 -1.620738e-03
## ASV0334     -7.062143e-04 -7.306170e-04 -7.554594e-04 -7.807146e-04
## ASV1311      8.776592e-04  9.105393e-04  9.442413e-04  9.787481e-04
## ASV0458      1.287315e-03  1.334552e-03  1.382908e-03  1.432355e-03
## ASV1371      2.357295e-04  2.475134e-04  2.598852e-04  2.728722e-04
## ASV0418      3.077528e-03  3.205023e-03  3.337013e-03  3.473594e-03
## ASV0004      4.444093e-04  4.626150e-04  4.814428e-04  5.009041e-04
## ASV1943      8.144870e-03  8.438473e-03  8.738877e-03  9.045941e-03
## ASV1495     -7.350725e-04 -7.792443e-04 -8.262675e-04 -8.763321e-04
## ASV0901     -2.721001e-03 -2.846795e-03 -2.978252e-03 -3.115612e-03
## ASV0628      1.362149e-03  1.415729e-03  1.470912e-03  1.527701e-03
## ASV0400      8.469761e-04  8.824066e-04  9.190964e-04  9.570701e-04
## ASV0116     -7.988368e-04 -8.356084e-04 -8.740189e-04 -9.141367e-04
## ASV0788      7.073190e-03  7.400126e-03  7.741749e-03  8.098683e-03
## ASV0117      5.312767e-04  5.569269e-04  5.838167e-04  6.120047e-04
## ASV3137     -1.596165e-04 -1.663317e-04 -1.732912e-04 -1.805004e-04
## ASV0001      4.753341e-04  4.945883e-04  5.144784e-04  5.350136e-04
## ASV1651      1.363283e-03  1.419549e-03  1.477778e-03  1.538007e-03
## ASV1692      5.882664e-03  6.153586e-03  6.436574e-03  6.732129e-03
## ASV0660      1.964299e-03  2.039707e-03  2.117171e-03  2.196669e-03
## ASV0508      9.692504e-05  1.004813e-04  1.041232e-04  1.078490e-04
## ASV1660     -1.229263e-03 -1.290556e-03 -1.354941e-03 -1.422571e-03
## ASV0233      1.794175e-03  1.874292e-03  1.957762e-03  2.044708e-03
## ASV1343     -3.343568e-03 -3.496853e-03 -3.656914e-03 -3.824028e-03
## ASV0209      1.591959e-03  1.656698e-03  1.723598e-03  1.792693e-03
## ASV0193     -1.867266e-03 -1.944147e-03 -2.023673e-03 -2.105889e-03
## ASV0357      7.947298e-04  8.365822e-04  8.807709e-04  9.274344e-04
## ASV0198      1.440567e-03  1.502538e-03  1.566905e-03  1.633740e-03
## ASV0007      4.154147e-04  4.317567e-04  4.485931e-04  4.659263e-04
## ASV1772     -6.056635e-04 -6.277738e-04 -6.503205e-04 -6.732698e-04
## ASV0009      3.394403e-04  3.523557e-04  3.656198e-04  3.792297e-04
## ASV0006     -4.053968e-04 -4.248246e-04 -4.451805e-04 -4.665080e-04
## ASV0011     -1.374619e-03 -1.437133e-03 -1.502360e-03 -1.570408e-03
## ASV0015      2.563449e-04  2.660672e-04  2.760472e-04  2.862820e-04
## ASV0017      2.891623e-04  3.001836e-04  3.115049e-04  3.231244e-04
## ASV0235     -1.274907e-03 -1.333385e-03 -1.394438e-03 -1.458171e-03
## ASV0382      9.965663e-04  1.041965e-03  1.089301e-03  1.138640e-03
## ASV2357      4.137921e-03  4.325829e-03  4.521888e-03  4.726421e-03
## ASV0567     -8.070995e-04 -8.444633e-04 -8.835313e-04 -9.243807e-04
## ASV0165      6.900085e-04  7.212655e-04  7.538635e-04  7.878534e-04
## ASV0005      9.875949e-04  1.030848e-03  1.075829e-03  1.122595e-03
## ASV0384     -7.582498e-05 -7.557359e-05 -7.498510e-05 -7.401847e-05
## ASV0002      1.812965e-04  1.888712e-04  1.967216e-04  2.048550e-04
## ASV3017      5.116413e-03  5.327875e-03  5.546703e-03  5.773040e-03
## ASV0091     -1.314518e-04 -1.371292e-04 -1.430370e-04 -1.491844e-04
## ASV0186     -1.997859e-03 -2.086148e-03 -2.178031e-03 -2.273628e-03
## ASV0370      1.047079e-03  1.091963e-03  1.138555e-03  1.186902e-03
## ASV0018      1.267791e-03  1.323612e-03  1.381691e-03  1.442104e-03
## ASV1377      1.247731e-02  1.300099e-02  1.354369e-02  1.410583e-02
## ASV0019      1.330860e-03  1.389553e-03  1.450631e-03  1.514172e-03
## ASV0023     -8.466915e-04 -8.856740e-04 -9.263857e-04 -9.688968e-04
## ASV2194      1.371871e-03  1.436334e-03  1.503791e-03  1.574379e-03
## ASV1155      5.216550e-03  5.435847e-03  5.663288e-03  5.899099e-03
## ASV0510     -1.354458e-03 -1.406243e-03 -1.459449e-03 -1.514070e-03
## ASV2371     -3.141485e-03 -3.273413e-03 -3.410197e-03 -3.551964e-03
## ASV0024     -1.052218e-03 -1.100437e-03 -1.150776e-03 -1.203321e-03
## ASV2452      3.091015e-03  3.213057e-03  3.338803e-03  3.468270e-03
## ASV2332     -9.073696e-03 -9.460647e-03 -9.862378e-03 -1.027933e-02
## ASV2591      2.572758e-03  2.703609e-03  2.841131e-03  2.985643e-03
## ASV0521      2.136362e-03  2.234155e-03  2.336250e-03  2.442824e-03
## ASV5542      2.044478e-03  2.137720e-03  2.234981e-03  2.336413e-03
## ASV0336     -2.930365e-04 -3.102766e-04 -3.285857e-04 -3.480303e-04
## ASV10102     3.774685e-03  3.946855e-03  4.126506e-03  4.313927e-03
## ASV16823    -5.554027e-03 -5.778264e-03 -6.009994e-03 -6.249354e-03
## ASV3104      2.872922e-02  2.988878e-02  3.108706e-02  3.232477e-02
## ASV0781      4.145398e-03  4.327540e-03  4.517045e-03  4.714158e-03
## ASV10899     2.616445e-03  2.751715e-03  2.894210e-03  3.044320e-03
## ASV11222    -9.771592e-03 -1.016596e-02 -1.057349e-02 -1.099444e-02
## ASV11327    -8.770564e-03 -9.124423e-03 -9.490092e-03 -9.867782e-03
## ASV12458    -9.765803e-03 -1.015970e-02 -1.056673e-02 -1.098713e-02
## ASV1636      5.625411e-03  5.863803e-03  6.111056e-03  6.367400e-03
## ASV1890     -4.391331e-03 -4.557416e-03 -4.728109e-03 -4.903414e-03
## ASV2898      7.548281e-03  7.868895e-03  8.201505e-03  8.546431e-03
## ASV8328      1.186966e-03  1.270988e-03  1.361133e-03  1.457832e-03
## ASV0709     -8.485478e-03 -8.853511e-03 -9.235921e-03 -9.633137e-03
## ASV0856      7.265044e-03  7.605094e-03  7.960669e-03  8.332432e-03
## ASV0909      2.271170e-03  2.396977e-03  2.530144e-03  2.671109e-03
## ASV0937     -5.085947e-03 -5.318389e-03 -5.561121e-03 -5.814576e-03
## ASV11390    -1.393483e-02 -1.449679e-02 -1.507749e-02 -1.567726e-02
## ASV11966     3.604154e-03  3.777793e-03  3.959721e-03  4.150314e-03
## ASV12990     2.467462e-03  2.570442e-03  2.677071e-03  2.787427e-03
## ASV14797     3.633495e-03  3.782976e-03  3.937623e-03  4.097539e-03
## ASV14904    -1.999495e-02 -2.080128e-02 -2.163450e-02 -2.249509e-02
## ASV15304     2.309031e-03  2.425760e-03  2.548466e-03  2.677443e-03
## ASV16696    -6.907223e-03 -7.185722e-03 -7.473505e-03 -7.770740e-03
## ASV1690      1.235987e-02  1.293894e-02  1.354426e-02  1.417692e-02
## ASV2029      8.324562e-03  8.684147e-03  9.057757e-03  9.445823e-03
## ASV2834      1.060741e-02  1.108560e-02  1.158415e-02  1.210379e-02
## ASV4003      8.980006e-03  9.415594e-03  9.872484e-03  1.035172e-02
## ASV4064      5.055111e-03  5.285344e-03  5.525546e-03  5.776101e-03
## ASV4294      3.197145e-03  3.359340e-03  3.529981e-03  3.709513e-03
## ASV4609      2.807469e-03  2.927660e-03  3.052429e-03  3.181908e-03
## ASV6283     -6.458139e-03 -6.718632e-03 -6.987821e-03 -7.265865e-03
## ASV6491     -9.253781e-03 -9.626926e-03 -1.001252e-02 -1.041079e-02
## ASV7453      4.795595e-03  5.028402e-03  5.272457e-03  5.528281e-03
## ASV7959      1.823342e-03  1.923075e-03  2.028500e-03  2.139944e-03
## ASV8219      7.996315e-02  8.318743e-02  8.651928e-02  8.996066e-02
## ASV8547     -8.281526e-03 -8.615353e-03 -8.960312e-03 -9.316601e-03
## ASV9319      3.802906e-03  3.980099e-03  4.165331e-03  4.358948e-03
## ASV9382     -1.620138e-02 -1.685438e-02 -1.752915e-02 -1.822608e-02
## ASV11516    -1.081803e-02 -1.125392e-02 -1.170433e-02 -1.216952e-02
## ASV14377    -7.808888e-03 -8.123438e-03 -8.448459e-03 -8.784140e-03
## ASV1867      6.325050e-03  6.613394e-03  6.914295e-03  7.228249e-03
## ASV1895      3.022540e-03  3.141533e-03  3.264044e-03  3.390069e-03
## ASV3168      3.852797e-03  4.010686e-03  4.173899e-03  4.342520e-03
## ASV4449      2.171853e-02  2.267305e-02  2.366652e-02  2.470030e-02
## ASV6596      4.735267e-03  4.969134e-03  5.214747e-03  5.472701e-03
## ASV7492     -6.251605e-04 -6.293542e-04 -6.317946e-04 -6.322723e-04
## ASV9854     -1.656170e-03 -1.721416e-03 -1.788746e-03 -1.858194e-03
## ASV6296      1.309925e-01  1.362675e-01  1.417179e-01  1.473470e-01
## ASV4201      8.636313e-04  9.267659e-04  9.946100e-04  1.067501e-03
## ASV0552      4.365817e-03  4.563524e-03  4.769721e-03  4.984734e-03
## ASV3671     -2.858837e-03 -2.982940e-03 -3.112074e-03 -3.246426e-03
## ASV3529     -5.915788e-04 -5.994135e-04 -6.061433e-04 -6.116303e-04
## ASV1060      1.181863e-03  1.237968e-03  1.296737e-03  1.358295e-03
## ASV0239     -1.494263e-03 -1.552979e-03 -1.613482e-03 -1.675786e-03
## ASV5711     -6.953072e-03 -7.249771e-03 -7.557838e-03 -7.877615e-03
## ASV4152     -9.990847e-03 -1.043565e-02 -1.089902e-02 -1.138162e-02
## ASV1461      4.842017e-03  5.034567e-03  5.233155e-03  5.437839e-03
## ASV2877      2.530766e-03  2.633269e-03  2.739139e-03  2.848420e-03
## ASV0012      4.504206e-04  4.703491e-04  4.910978e-04  5.126957e-04
## ASV9823      5.712036e-04  5.880383e-04  6.047852e-04  6.213696e-04
## ASV0008      4.787131e-04  4.996898e-04  5.215137e-04  5.442138e-04
## ASV7832     -5.901975e-03 -6.167518e-03 -6.444457e-03 -6.733243e-03
## ASV1915     -7.282219e-04 -7.588176e-04 -7.906022e-04 -8.236207e-04
## ASV0055     -5.486439e-04 -5.765190e-04 -6.058538e-04 -6.367259e-04
## ASV0032      2.210264e-04  2.285881e-04  2.362732e-04  2.440713e-04
## ASV2977     -8.271219e-03 -8.637271e-03 -9.018398e-03 -9.415132e-03
## ASV0466      6.411211e-03  6.666799e-03  6.930474e-03  7.202319e-03
## ASV3866      4.614586e-03  4.827156e-03  5.049201e-03  5.281116e-03
## ASV0040      1.650943e-03  1.725092e-03  1.802382e-03  1.882930e-03
## ASV0496     -4.884663e-04 -5.217954e-04 -5.575061e-04 -5.957652e-04
## ASV0052      1.387128e-03  1.449541e-03  1.514605e-03  1.582419e-03
## ASV3828     -4.631898e-03 -4.817473e-03 -5.009136e-03 -5.206991e-03
## ASV1930      2.412882e-03  2.513593e-03  2.617865e-03  2.725768e-03
## ASV2126      4.161168e-03  4.341099e-03  4.528060e-03  4.722270e-03
## ASV0793      5.213712e-03  5.452132e-03  5.701001e-03  5.960738e-03
## ASV0299     -1.070307e-04 -1.126720e-04 -1.186721e-04 -1.250611e-04
## ASV0208      3.737652e-03  3.905493e-03  4.080457e-03  4.262813e-03
## ASV0511     -1.464028e-03 -1.520949e-03 -1.579523e-03 -1.639752e-03
## ASV1123     -4.456595e-03 -4.633602e-03 -4.816197e-03 -5.004444e-03
## ASV0099      1.517986e-04  1.601196e-04  1.689391e-04  1.782902e-04
## ASV0752     -2.715269e-03 -2.843549e-03 -2.977788e-03 -3.118252e-03
## ASV0883      3.714921e-03  3.889277e-03  4.071627e-03  4.262317e-03
## ASV0683      4.829229e-03  5.052810e-03  5.286419e-03  5.530477e-03
## ASV4117     -7.600229e-03 -7.941658e-03 -8.297659e-03 -8.668800e-03
## ASV2172      4.484130e-04  4.631138e-04  4.779549e-04  4.929004e-04
## ASV0330     -1.427197e-03 -1.492099e-03 -1.559825e-03 -1.630487e-03
## ASV0728      6.969083e-03  7.275875e-03  7.595069e-03  7.927071e-03
## ASV0499      1.883773e-03  1.971565e-03  2.063354e-03  2.159312e-03
## ASV0120     -3.094996e-03 -3.231713e-03 -3.373993e-03 -3.522020e-03
## ASV1446      2.203171e-03  2.280159e-03  2.358585e-03  2.438358e-03
## ASV17171    -5.971323e-03 -6.234956e-03 -6.509482e-03 -6.795301e-03
## ASV0533      4.656015e-04  4.886321e-04  5.128185e-04  5.382186e-04
## ASV2495     -1.564060e-03 -1.645539e-03 -1.731502e-03 -1.822207e-03
## ASV5582      2.609343e-03  2.706195e-03  2.805439e-03  2.907032e-03
## ASV1488      1.032624e-03  1.075355e-03  1.119556e-03  1.165249e-03
## ASV0682      1.376867e-03  1.441525e-03  1.509161e-03  1.579905e-03
## ASV0068     -2.350467e-03 -2.455088e-03 -2.564036e-03 -2.677460e-03
## ASV1987     -5.998327e-03 -6.283078e-03 -6.581170e-03 -6.893202e-03
## ASV0035     -4.968989e-04 -5.267570e-04 -5.585694e-04 -5.924716e-04
## ASV7192     -3.584585e-03 -3.737726e-03 -3.896708e-03 -4.061699e-03
## ASV0873     -1.514157e-03 -1.709677e-03 -1.923490e-03 -2.156987e-03
## ASV4749     -3.122415e-04 -3.495530e-04 -3.904491e-04 -4.352277e-04
## ASV2174      2.400414e-03  2.491591e-03  2.585202e-03  2.681223e-03
## ASV1476     -2.645663e-03 -2.769975e-03 -2.900079e-03 -3.036242e-03
## ASV0740     -7.497560e-03 -7.847516e-03 -8.213455e-03 -8.596074e-03
## ASV0170     -1.443256e-03 -1.507736e-03 -1.574918e-03 -1.644903e-03
## ASV2466     -6.584058e-03 -6.878994e-03 -7.186427e-03 -7.506834e-03
## ASV1709      2.359829e-03  2.459547e-03  2.563117e-03  2.670672e-03
## ASV6170     -1.040930e-02 -1.088730e-02 -1.138648e-02 -1.190769e-02
## ASV3673      5.142835e-03  5.382701e-03  5.633499e-03  5.895703e-03
## ASV1745     -1.361335e-03 -1.428344e-03 -1.498701e-03 -1.572571e-03
##                                                                    
## (Intercept)  4.170387e-02  4.353915e-02  4.544834e-02  4.743384e-02
## ASV1236      8.004150e-03  8.334913e-03  8.677372e-03  9.031796e-03
## ASV0421      1.079617e-03  1.140404e-03  1.204754e-03  1.272872e-03
## ASV0691     -5.904277e-03 -6.117067e-03 -6.334755e-03 -6.557240e-03
## ASV0899      6.956108e-03  7.244507e-03  7.543013e-03  7.851826e-03
## ASV1004      1.606097e-02  1.672713e-02  1.741691e-02  1.813081e-02
## ASV1041     -6.569859e-03 -6.838026e-03 -7.115141e-03 -7.401330e-03
## ASV1058      1.001289e-02  1.042738e-02  1.085654e-02  1.130070e-02
## ASV12542     3.818285e-03  3.970252e-03  4.127096e-03  4.288889e-03
## ASV1294      9.329167e-03  9.716373e-03  1.011737e-02  1.053248e-02
## ASV13113     3.333128e-03  3.492795e-03  3.660103e-03  3.835411e-03
## ASV1318      9.294936e-03  9.679786e-03  1.007823e-02  1.049056e-02
## ASV2269     -1.604813e-02 -1.670736e-02 -1.738926e-02 -1.809426e-02
## ASV2542      8.174166e-03  8.545243e-03  8.932418e-03  9.336330e-03
## ASV2660     -6.360554e-03 -6.619533e-03 -6.887256e-03 -7.163877e-03
## ASV2737      2.137129e-03  2.218215e-03  2.301590e-03  2.387261e-03
## ASV2840      8.325438e-03  8.649117e-03  8.982322e-03  9.325086e-03
## ASV3053      4.305290e-02  4.477412e-02  4.655119e-02  4.838498e-02
## ASV3077      2.755480e-03  2.866688e-03  2.981620e-03  3.100348e-03
## ASV3134      5.259230e-03  5.505444e-03  5.762984e-03  6.032354e-03
## ASV3140      6.923821e-03  7.228173e-03  7.544813e-03  7.874147e-03
## ASV3579      2.611714e-03  2.741720e-03  2.878304e-03  3.021798e-03
## ASV6119     -4.390776e-03 -4.571085e-03 -4.757595e-03 -4.950421e-03
## ASV7557     -8.919800e-03 -9.285955e-03 -9.664688e-03 -1.005623e-02
## ASV8422      2.201019e-03  2.289495e-03  2.380903e-03  2.475298e-03
## ASV1086     -3.216918e-04 -3.326517e-04 -3.438283e-04 -3.552163e-04
## ASV1310      4.282431e-03  4.459100e-03  4.641937e-03  4.831071e-03
## ASV15750    -5.554846e-04 -5.756928e-04 -5.963525e-04 -6.174482e-04
## ASV16905    -1.834205e-03 -1.909499e-03 -1.987379e-03 -2.067895e-03
## ASV2033      8.266734e-03  8.646967e-03  9.043989e-03  9.458469e-03
## ASV2089      3.870780e-03  4.029952e-03  4.194615e-03  4.364871e-03
## ASV2127      1.259057e-02  1.311070e-02  1.364911e-02  1.420620e-02
## ASV2725      9.956958e-03  1.035738e-02  1.077093e-02  1.119782e-02
## ASV2804     -3.796471e-03 -3.952302e-03 -4.113487e-03 -4.280126e-03
## ASV3075      8.540640e-03  8.913104e-03  9.300611e-03  9.703695e-03
## ASV3327      1.202215e-02  1.256414e-02  1.312920e-02  1.371820e-02
## ASV3342      1.028170e-02  1.074089e-02  1.121932e-02  1.171770e-02
## ASV3532     -1.124659e-02 -1.174026e-02 -1.225397e-02 -1.278840e-02
## ASV3600      5.246172e-03  5.478099e-03  5.719563e-03  5.970900e-03
## ASV4013      9.615944e-03  1.002514e-02  1.044974e-02  1.089018e-02
## ASV4136      1.002346e-02  1.042969e-02  1.084963e-02  1.128354e-02
## ASV4195      3.874043e-02  4.032999e-02  4.197412e-02  4.367385e-02
## ASV4407     -1.496316e-02 -1.557688e-02 -1.621164e-02 -1.686785e-02
## ASV4717      2.491852e-03  2.584160e-03  2.678862e-03  2.775947e-03
## ASV6794      6.086648e-03  6.326800e-03  6.574553e-03  6.830017e-03
## ASV8324     -7.677964e-03 -7.992871e-03 -8.318577e-03 -8.655283e-03
## ASV8981     -1.102239e-04 -1.071821e-04 -1.033314e-04 -9.858701e-05
## ASV9859      2.979572e-03  3.131989e-03  3.292512e-03  3.461589e-03
## ASV0936      7.754594e-03  8.100582e-03  8.460933e-03  8.836149e-03
## ASV12683    -3.302049e-05 -3.646593e-05 -4.018171e-05 -4.418208e-05
## ASV1293      4.974617e-03  5.178281e-03  5.388934e-03  5.606709e-03
## ASV13055    -5.894310e-05 -5.583356e-05 -5.210455e-05 -4.769420e-05
## ASV17063    -3.979278e-03 -4.142284e-03 -4.310867e-03 -4.485129e-03
## ASV2228      3.244113e-03  3.376953e-03  3.514333e-03  3.656337e-03
## ASV2769      5.984903e-04  6.310091e-04  6.653415e-04  7.015845e-04
## ASV2803      3.421282e-03  3.553518e-03  3.689642e-03  3.829678e-03
## ASV2896      2.951036e-03  3.085653e-03  3.226223e-03  3.373000e-03
## ASV3062      3.689889e-03  3.868908e-03  4.056610e-03  4.253405e-03
## ASV3107      5.456778e-03  5.701351e-03  5.956289e-03  6.221987e-03
## ASV3265      7.101940e-03  7.391187e-03  7.690212e-03  7.999187e-03
## ASV3666      5.848179e-05  5.980535e-05  6.106054e-05  6.223330e-05
## ASV4497      2.466130e-03  2.569023e-03  2.675621e-03  2.786014e-03
## ASV6914     -4.225095e-04 -4.450217e-04 -4.687735e-04 -4.938318e-04
## ASV0576     -8.224974e-03 -8.537822e-03 -8.859418e-03 -9.189768e-03
## ASV0673      9.557036e-03  9.960884e-03  1.037969e-02  1.081383e-02
## ASV0772      4.467660e-03  4.659576e-03  4.858922e-03  5.065924e-03
## ASV0862      6.532448e-04  7.009972e-04  7.522342e-04  8.071884e-04
## ASV0898      3.614375e-03  3.782146e-03  3.957416e-03  4.140485e-03
## ASV0910      4.108072e-03  4.293663e-03  4.487220e-03  4.689051e-03
## ASV0964     -3.141151e-03 -3.263310e-03 -3.389094e-03 -3.518525e-03
## ASV10059     3.001782e-03  3.144295e-03  3.293493e-03  3.449680e-03
## ASV10263    -6.069367e-03 -6.318611e-03 -6.576440e-03 -6.843018e-03
## ASV1088      7.274664e-03  7.599543e-03  7.938169e-03  8.291074e-03
## ASV1101      8.655266e-03  9.008792e-03  9.374339e-03  9.752125e-03
## ASV1183      2.364409e-03  2.468003e-03  2.575774e-03  2.687862e-03
## ASV11956     2.139707e-03  2.220574e-03  2.303674e-03  2.389009e-03
## ASV12774     5.946692e-05  5.562023e-05  5.107737e-05  4.577280e-05
## ASV1321      1.067479e-02  1.116294e-02  1.167251e-02  1.220436e-02
## ASV13793    -4.184146e-03 -4.355924e-03 -4.533615e-03 -4.717329e-03
## ASV14482     2.445408e-04  2.528792e-04  2.614050e-04  2.701193e-04
## ASV15483     1.796546e-03  1.877172e-03  1.961193e-03  2.048735e-03
## ASV2062      8.143033e-03  8.488848e-03  8.847695e-03  9.219942e-03
## ASV2132      6.819928e-03  7.124679e-03  7.442184e-03  7.772902e-03
## ASV2413      6.225992e-03  6.484219e-03  6.751661e-03  7.028539e-03
## ASV2490      1.880462e-02  1.955185e-02  2.032288e-02  2.111801e-02
## ASV2594      2.468825e-03  2.578191e-03  2.692144e-03  2.810863e-03
## ASV2822     -1.104847e-02 -1.150256e-02 -1.197233e-02 -1.245808e-02
## ASV2863      1.166996e-02  1.214309e-02  1.263219e-02  1.313756e-02
## ASV2910      4.295225e-03  4.471379e-03  4.653618e-03  4.842067e-03
## ASV2980      4.879876e-03  5.087830e-03  5.303649e-03  5.527554e-03
## ASV3307      8.786123e-03  9.146941e-03  9.520190e-03  9.906113e-03
## ASV3474      6.161320e-03  6.447238e-03  6.746026e-03  7.058222e-03
## ASV3502      6.264474e-03  6.537321e-03  6.821029e-03  7.115955e-03
## ASV4236      8.791816e-03  9.136161e-03  9.490938e-03  9.856225e-03
## ASV4842     -1.015496e-03 -1.061077e-03 -1.108450e-03 -1.157655e-03
## ASV4894     -4.187048e-03 -4.359123e-03 -4.537139e-03 -4.721214e-03
## ASV5290      3.449886e-03  3.602991e-03  3.762399e-03  3.928328e-03
## ASV5501      2.092497e-03  2.184435e-03  2.280182e-03  2.379887e-03
## ASV5795      2.324593e-03  2.428376e-03  2.536492e-03  2.649097e-03
## ASV5987     -1.169826e-02 -1.217926e-02 -1.267691e-02 -1.319151e-02
## ASV6267     -1.317753e-02 -1.371915e-02 -1.427949e-02 -1.485891e-02
## ASV6862      5.214302e-03  5.422301e-03  5.637032e-03  5.858599e-03
## ASV7145      2.275119e-03  2.363949e-03  2.455580e-03  2.550064e-03
## ASV7673     -4.186682e-03 -4.358744e-03 -4.536750e-03 -4.720816e-03
## ASV7789      2.302456e-03  2.418384e-03  2.540296e-03  2.668502e-03
## ASV7809      2.259402e-04  2.429867e-04  2.613091e-04  2.809948e-04
## ASV8002     -5.287685e-03 -5.505032e-03 -5.729894e-03 -5.962420e-03
## ASV8205      2.290433e-03  2.391759e-03  2.497263e-03  2.607096e-03
## ASV9155     -1.320418e-03 -1.372456e-03 -1.426090e-03 -1.481330e-03
## ASV9221      6.947992e-04  7.375599e-04  7.831047e-04  8.316143e-04
## ASV9311     -8.481488e-03 -8.830106e-03 -9.190783e-03 -9.563757e-03
## ASV9557     -5.794676e-03 -6.032764e-03 -6.279080e-03 -6.533787e-03
## ASV9936     -1.168216e-02 -1.216196e-02 -1.265833e-02 -1.317159e-02
## ASV1445      7.345544e-03  7.670307e-03  8.008379e-03  8.360220e-03
## ASV4232      2.886814e-03  3.024744e-03  3.169303e-03  3.320812e-03
## ASV6479      1.170538e-03  1.238673e-03  1.311000e-03  1.387782e-03
## ASV0142     -5.010483e-03 -5.214104e-03 -5.424608e-03 -5.642121e-03
## ASV0378      2.455508e-03  2.572040e-03  2.694018e-03  2.821680e-03
## ASV1122      7.149235e-03  7.468969e-03  7.802126e-03  8.149198e-03
## ASV0123     -4.417677e-03 -4.596552e-03 -4.781413e-03 -4.972366e-03
## ASV2064      2.179698e-03  2.260134e-03  2.342511e-03  2.426784e-03
## ASV4459     -2.841802e-04 -2.928710e-04 -3.016400e-04 -3.104751e-04
## ASV0448      1.965427e-03  2.058852e-03  2.156654e-03  2.259027e-03
## ASV0397      4.129113e-03  4.307026e-03  4.491835e-03  4.683747e-03
## ASV0485      4.750031e-03  4.950393e-03  5.158186e-03  5.373611e-03
## ASV1566      7.053254e-03  7.355633e-03  7.669597e-03  7.995483e-03
## ASV1365      6.078849e-03  6.344293e-03  6.620269e-03  6.907105e-03
## ASV1065      8.627100e-03  9.003218e-03  9.394306e-03  9.800845e-03
## ASV0722     -4.659394e-04 -4.878483e-04 -5.107954e-04 -5.348321e-04
## ASV12660    -4.774181e-03 -4.966491e-03 -5.165188e-03 -5.370383e-03
## ASV0223      1.317402e-03  1.373529e-03  1.431798e-03  1.492275e-03
## ASV0229      2.063598e-03  2.156411e-03  2.253181e-03  2.354060e-03
## ASV0877      7.836807e-04  8.108879e-04  8.384856e-04  8.664155e-04
## ASV0983      4.691438e-03  4.886940e-03  5.089450e-03  5.299131e-03
## ASV0626      6.532236e-04  6.940053e-04  7.374036e-04  7.835763e-04
## ASV4146      2.233614e-04  2.314223e-04  2.395573e-04  2.477333e-04
## ASV4175     -5.961151e-03 -6.226384e-03 -6.502621e-03 -6.790252e-03
## ASV2082     -2.964642e-03 -3.123049e-03 -3.290372e-03 -3.467127e-03
## ASV2272      2.829284e-03  2.954602e-03  3.085121e-03  3.221033e-03
## ASV2245     -4.275848e-03 -4.467730e-03 -4.667698e-03 -4.876049e-03
## ASV0590     -2.871553e-03 -3.030921e-03 -3.199604e-03 -3.378153e-03
## ASV0217      4.180845e-04  4.544777e-04  4.938299e-04  5.363547e-04
## ASV0416      2.961277e-03  3.068250e-03  3.177617e-03  3.289305e-03
## ASV1056      4.183807e-03  4.375985e-03  4.576618e-03  4.786040e-03
## ASV7777     -5.778487e-03 -6.033825e-03 -6.299680e-03 -6.576432e-03
## ASV0455      1.029210e-03  1.073852e-03  1.120240e-03  1.168426e-03
## ASV0604      2.781925e-03  2.912176e-03  3.048355e-03  3.190709e-03
## ASV6100     -4.023867e-03 -4.205617e-03 -4.395197e-03 -4.592915e-03
## ASV11359    -8.554899e-03 -8.931808e-03 -9.324013e-03 -9.732025e-03
## ASV6604      1.218782e-03  1.275461e-03  1.334693e-03  1.396584e-03
## ASV5004     -3.025743e-03 -3.157701e-03 -3.294944e-03 -3.437651e-03
## ASV1483     -1.295201e-03 -1.350859e-03 -1.408661e-03 -1.468672e-03
## ASV9773     -3.873430e-03 -4.046163e-03 -4.226132e-03 -4.413605e-03
## ASV4059      1.600429e-04  1.809983e-04  2.039733e-04  2.291288e-04
## ASV1193      4.611835e-03  4.811076e-03  5.018096e-03  5.233133e-03
## ASV4610     -5.252240e-04 -5.301247e-04 -5.338268e-04 -5.361950e-04
## ASV0742     -2.663534e-04 -2.623530e-04 -2.569231e-04 -2.499224e-04
## ASV1502     -3.182013e-04 -3.420447e-04 -3.676681e-04 -3.951939e-04
## ASV0195      4.598518e-05  4.208853e-05  3.756129e-05  3.234742e-05
## ASV1213      3.082301e-03  3.200275e-03  3.321590e-03  3.446249e-03
## ASV1648     -3.609156e-03 -3.771839e-03 -3.941521e-03 -4.118481e-03
## ASV6984     -3.380468e-03 -3.533240e-03 -3.692629e-03 -3.858903e-03
## ASV0396     -1.157075e-04 -1.144207e-04 -1.126058e-04 -1.102160e-04
## ASV4297      4.538879e-03  4.718954e-03  4.904701e-03  5.096184e-03
## ASV2622      7.166543e-03  7.462976e-03  7.769886e-03  8.087508e-03
## ASV3512      3.087484e-03  3.243486e-03  3.407620e-03  3.580319e-03
## ASV2411      5.153329e-03  5.391770e-03  5.640897e-03  5.901152e-03
## ASV2291     -2.515458e-03 -2.657486e-03 -2.807930e-03 -2.967287e-03
## ASV0807      6.794140e-03  7.087580e-03  7.392418e-03  7.708992e-03
## ASV1292      1.523818e-03  1.579178e-03  1.635837e-03  1.693766e-03
## ASV1035      6.061759e-03  6.309056e-03  6.564880e-03  6.829416e-03
## ASV0070      1.284681e-04  1.409320e-04  1.544910e-04  1.692312e-04
## ASV0255      5.483425e-04  5.680145e-04  5.880734e-04  6.084940e-04
## ASV0057     -1.625889e-03 -1.688080e-03 -1.752008e-03 -1.817669e-03
## ASV0077     -3.170870e-04 -3.265626e-04 -3.360514e-04 -3.455257e-04
## ASV0625      3.462288e-03  3.600575e-03  3.743310e-03  3.890553e-03
## ASV2464      2.349495e-02  2.443029e-02  2.539588e-02  2.639220e-02
## ASV1315      6.742706e-03  7.057171e-03  7.385923e-03  7.729568e-03
## ASV2673      5.791549e-03  6.062377e-03  6.345574e-03  6.641671e-03
## ASV2161      2.443602e-03  2.557525e-03  2.676651e-03  2.801207e-03
## ASV0337     -1.370393e-03 -1.431652e-03 -1.495478e-03 -1.561964e-03
## ASV7680     -8.970758e-03 -9.374406e-03 -9.795221e-03 -1.023385e-02
## ASV0611      5.018784e-03  5.245526e-03  5.482015e-03  5.728632e-03
## ASV3118     -5.330654e-03 -5.581782e-03 -5.844505e-03 -6.119329e-03
## ASV1284      1.331540e-03  1.344720e-03  1.354550e-03  1.360596e-03
## ASV0889      3.661867e-03  3.815640e-03  3.975090e-03  4.140371e-03
## ASV4649     -1.875223e-03 -1.957559e-03 -2.043233e-03 -2.132362e-03
## ASV1108     -4.038894e-03 -4.233801e-03 -4.438120e-03 -4.652297e-03
## ASV0738      2.343992e-03  2.466744e-03  2.596184e-03  2.732685e-03
## ASV0473     -5.167557e-04 -5.466731e-04 -5.783467e-04 -6.118711e-04
## ASV0598     -1.240093e-03 -1.308647e-03 -1.381225e-03 -1.458069e-03
## ASV0429      2.674768e-03  2.782778e-03  2.894323e-03  3.009451e-03
## ASV1549      5.351129e-03  5.602013e-03  5.864408e-03  6.138815e-03
## ASV1203      3.993377e-03  4.161674e-03  4.336168e-03  4.517015e-03
## ASV4532      1.403007e-04  1.436417e-04  1.469246e-04  1.501379e-04
## ASV0274      7.602126e-04  7.978397e-04  8.373092e-04  8.787031e-04
## ASV0163     -2.999644e-03 -3.118917e-03 -3.242023e-03 -3.369021e-03
## ASV1298      2.997227e-04  3.094601e-04  3.193873e-04  3.295065e-04
## ASV9424     -6.989169e-03 -7.307062e-03 -7.638824e-03 -7.985016e-03
## ASV0412      6.891244e-03  7.178729e-03  7.476594e-03  7.785092e-03
## ASV0284      1.324180e-03  1.368979e-03  1.414464e-03  1.460567e-03
## ASV0620     -1.602935e-03 -1.686667e-03 -1.774915e-03 -1.867921e-03
## ASV0153     -7.150176e-03 -7.484853e-03 -7.834806e-03 -8.200687e-03
## ASV0498      2.468432e-03  2.579060e-03  2.694285e-03  2.814263e-03
## ASV0097      1.404811e-03  1.470650e-03  1.539512e-03  1.611529e-03
## ASV0104     -9.479797e-03 -9.885540e-03 -1.030673e-02 -1.074380e-02
## ASV1282      3.168054e-03  3.294475e-03  3.424856e-03  3.559226e-03
## ASV3883     -2.812914e-03 -2.951800e-03 -3.097563e-03 -3.250529e-03
## ASV0801      1.316042e-03  1.375146e-03  1.436752e-03  1.500955e-03
## ASV1611     -6.317319e-03 -6.608827e-03 -6.913355e-03 -7.231445e-03
## ASV0227     -1.268907e-03 -1.338118e-03 -1.411253e-03 -1.488532e-03
## ASV0833      2.109561e-03  2.203454e-03  2.301228e-03  2.403020e-03
## ASV0718      9.407738e-03  9.824694e-03  1.025887e-02  1.071087e-02
## ASV1139      1.005410e-03  1.031921e-03  1.057984e-03  1.083457e-03
## ASV0766     -1.402042e-03 -1.471455e-03 -1.544308e-03 -1.620765e-03
## ASV2091      7.276521e-03  7.567434e-03  7.867692e-03  8.177415e-03
## ASV1238     -7.105527e-03 -7.430709e-03 -7.770337e-03 -8.125025e-03
## ASV9193     -8.496279e-04 -9.029715e-04 -9.599006e-04 -1.020661e-03
## ASV0290      8.744988e-04  9.030956e-04  9.320892e-04  9.614423e-04
## ASV0231      2.710678e-03  2.823442e-03  2.940223e-03  3.061113e-03
## ASV0185      1.791790e-03  1.885115e-03  1.983491e-03  2.087197e-03
## ASV2330      3.007108e-03  3.123610e-03  3.243538e-03  3.366910e-03
## ASV3119     -1.611925e-03 -1.694964e-03 -1.782417e-03 -1.874520e-03
## ASV2368     -3.714216e-03 -3.889924e-03 -4.073911e-03 -4.266566e-03
## ASV0122     -1.700277e-03 -1.772435e-03 -1.847303e-03 -1.924957e-03
## ASV1044      4.553677e-03  4.764011e-03  4.983763e-03  5.213328e-03
## ASV0160     -1.754861e-03 -1.823303e-03 -1.893812e-03 -1.966406e-03
## ASV0326      4.950492e-04  5.170377e-04  5.399171e-04  5.637146e-04
## ASV1388      8.847194e-03  9.224536e-03  9.616142e-03  1.002241e-02
## ASV0792      6.432389e-03  6.695408e-03  6.967413e-03  7.248573e-03
## ASV0036     -2.145567e-03 -2.245957e-03 -2.350909e-03 -2.460614e-03
## ASV2125      6.360943e-03  6.635423e-03  6.920554e-03  7.216651e-03
## ASV1075     -9.718943e-05 -1.016504e-04 -1.063321e-04 -1.112488e-04
## ASV0390      3.546692e-03  3.713480e-03  3.888014e-03  4.070647e-03
## ASV3790     -4.917209e-03 -5.138136e-03 -5.368441e-03 -5.608476e-03
## ASV1535     -1.525252e-03 -1.602932e-03 -1.684670e-03 -1.770675e-03
## ASV0263      5.950595e-03  6.211723e-03  6.483398e-03  6.765975e-03
## ASV0675      9.121494e-03  9.537431e-03  9.971524e-03  1.042450e-02
## ASV3348      7.723457e-04  8.103052e-04  8.501354e-04  8.919252e-04
## ASV0058     -2.609509e-03 -2.720177e-03 -2.834972e-03 -2.954002e-03
## ASV4142      3.584819e-03  3.730075e-03  3.880147e-03  4.035109e-03
## ASV0059     -2.089121e-03 -2.176577e-03 -2.267194e-03 -2.361045e-03
## ASV0013     -3.791840e-03 -3.957563e-03 -4.129912e-03 -4.309105e-03
## ASV0033     -1.859596e-03 -1.946179e-03 -2.036668e-03 -2.131225e-03
## ASV4354     -2.241195e-03 -2.340202e-03 -2.443323e-03 -2.550714e-03
## ASV0022     -1.569230e-03 -1.642230e-03 -1.718523e-03 -1.798249e-03
## ASV0134     -1.536599e-03 -1.611874e-03 -1.690871e-03 -1.773770e-03
## ASV0415      2.726901e-04  2.879015e-04  3.039618e-04  3.209131e-04
## ASV10103    -8.622203e-03 -9.015663e-03 -9.426321e-03 -9.854864e-03
## ASV1613      6.101206e-03  6.350650e-03  6.608559e-03  6.875080e-03
## ASV0135     -7.600575e-04 -7.889755e-04 -8.186836e-04 -8.491778e-04
## ASV0469     -7.978161e-03 -8.314507e-03 -8.663353e-03 -9.025044e-03
## ASV0471      4.933425e-03  5.148047e-03  5.371178e-03  5.603092e-03
## ASV0451     -9.480139e-04 -1.001633e-03 -1.058430e-03 -1.118592e-03
## ASV0747      2.838612e-03  2.964731e-03  3.096052e-03  3.232754e-03
## ASV1314     -2.944875e-03 -3.084362e-03 -3.230410e-03 -3.383320e-03
## ASV0425     -9.698609e-03 -1.009116e-02 -1.049680e-02 -1.091575e-02
## ASV0559     -2.476454e-03 -2.584281e-03 -2.696493e-03 -2.813253e-03
## ASV0148     -4.672280e-04 -4.790314e-04 -4.905497e-04 -5.017086e-04
## ASV0129      7.635169e-04  8.132672e-04  8.664544e-04  9.233160e-04
## ASV1072      6.039325e-04  6.245808e-04  6.455399e-04  6.667741e-04
## ASV2390      4.881272e-03  5.070297e-03  5.264756e-03  5.464646e-03
## ASV0548      3.385200e-03  3.531542e-03  3.683589e-03  3.841512e-03
## ASV0168     -1.711797e-03 -1.783563e-03 -1.857950e-03 -1.935024e-03
## ASV0066     -1.940577e-03 -2.022855e-03 -2.108187e-03 -2.196652e-03
## ASV0468     -1.047648e-03 -1.093979e-03 -1.142223e-03 -1.192449e-03
## ASV0172     -5.310681e-04 -5.490256e-04 -5.672435e-04 -5.856918e-04
## ASV0236      1.201280e-04  1.458432e-04  1.743400e-04  2.058534e-04
## ASV0250      2.983437e-03  3.132616e-03  3.289432e-03  3.454283e-03
## ASV0338      1.361561e-03  1.424665e-03  1.490534e-03  1.559269e-03
## ASV0450     -2.977136e-04 -3.152959e-04 -3.339779e-04 -3.538292e-04
## ASV0377      2.418977e-03  2.521153e-03  2.627103e-03  2.736922e-03
## ASV1022     -9.307596e-05 -9.594212e-05 -9.878695e-05 -1.015939e-04
## ASV6174     -8.028375e-05 -8.631615e-05 -9.283330e-05 -9.987380e-05
## ASV0786     -4.366404e-04 -4.637990e-04 -4.926912e-04 -5.234214e-04
## ASV0053     -2.670742e-03 -2.788398e-03 -2.910833e-03 -3.038206e-03
## ASV0697     -1.569602e-03 -1.634104e-03 -1.700864e-03 -1.769932e-03
## ASV0785      3.353218e-03  3.495111e-03  3.642278e-03  3.794859e-03
## ASV1967     -3.312354e-03 -3.451211e-03 -3.595185e-03 -3.744415e-03
## ASV0385      1.190156e-03  1.246506e-03  1.305444e-03  1.367076e-03
## ASV0295      2.738748e-04  2.923288e-04  3.120912e-04  3.332535e-04
## ASV0072     -2.573093e-03 -2.678921e-03 -2.788389e-03 -2.901562e-03
## ASV0157     -2.287186e-04 -2.288895e-04 -2.281916e-04 -2.265194e-04
## ASV0501      5.783673e-03  6.039892e-03  6.306618e-03  6.584208e-03
## ASV10729    -7.314938e-03 -7.643334e-03 -7.985628e-03 -8.342336e-03
## ASV1470      3.468726e-03  3.601719e-03  3.738449e-03  3.878908e-03
## ASV0050     -6.147675e-03 -6.408973e-03 -6.680064e-03 -6.961210e-03
## ASV0411     -1.449015e-03 -1.516195e-03 -1.586401e-03 -1.659761e-03
## ASV0549      2.306194e-03  2.411068e-03  2.520484e-03  2.634618e-03
## ASV0184      7.481270e-04  7.803320e-04  8.138115e-04  8.486098e-04
## ASV0705      1.452273e-03  1.511919e-03  1.573601e-03  1.637354e-03
## ASV1715      3.169712e-03  3.308992e-03  3.453901e-03  3.604626e-03
## ASV0603      5.096129e-04  5.336169e-04  5.587707e-04  5.851334e-04
## ASV0826      5.294801e-03  5.522578e-03  5.759170e-03  6.004842e-03
## ASV0034     -1.666757e-03 -1.735782e-03 -1.807233e-03 -1.881161e-03
## ASV0838      9.228750e-04  9.398063e-04  9.552804e-04  9.690549e-04
## ASV0614     -1.447800e-03 -1.509946e-03 -1.574490e-03 -1.641501e-03
## ASV0014     -3.853052e-03 -4.019697e-03 -4.192849e-03 -4.372706e-03
## ASV0585      2.389045e-04  2.324986e-04  2.244055e-04  2.144540e-04
## ASV0016     -4.024946e-03 -4.199018e-03 -4.379887e-03 -4.567759e-03
## ASV5394     -3.055431e-03 -3.190952e-03 -3.332055e-03 -3.478936e-03
## ASV0666      6.404487e-03  6.665769e-03  6.935942e-03  7.215171e-03
## ASV2085      1.206167e-03  1.230857e-03  1.254182e-03  1.275909e-03
## ASV0003     -2.742265e-03 -2.860665e-03 -2.983672e-03 -3.111426e-03
## ASV0346      1.441242e-03  1.508913e-03  1.579656e-03  1.653598e-03
## ASV0267      5.128460e-05  5.912142e-05  6.774224e-05  7.720870e-05
## ASV0353      2.263357e-03  2.367559e-03  2.476384e-03  2.590024e-03
## ASV2419      5.860103e-03  6.109371e-03  6.368036e-03  6.636358e-03
## ASV0447      3.326738e-03  3.480471e-03  3.641047e-03  3.808743e-03
## ASV0654      4.773222e-03  4.980235e-03  5.195364e-03  5.418854e-03
## ASV0151      7.131612e-04  7.510800e-04  7.911117e-04  8.333766e-04
## ASV0065     -1.830461e-03 -1.908386e-03 -1.989248e-03 -2.073128e-03
## ASV0527      4.524075e-03  4.718826e-03  4.921115e-03  5.131169e-03
## ASV4055     -7.752115e-04 -8.143141e-04 -8.554903e-04 -8.988593e-04
## ASV0166     -2.216416e-03 -2.306752e-03 -2.400148e-03 -2.496657e-03
## ASV0417     -8.702552e-04 -9.023446e-04 -9.352136e-04 -9.688467e-04
## ASV0078     -1.321437e-03 -1.375924e-03 -1.432291e-03 -1.490573e-03
## ASV0322     -1.826033e-04 -1.841435e-04 -1.850948e-04 -1.853710e-04
## ASV0156     -3.272051e-03 -3.419241e-03 -3.572713e-03 -3.732707e-03
## ASV0648     -7.134933e-03 -7.458230e-03 -7.795462e-03 -8.147169e-03
## ASV0407     -5.487655e-04 -5.749173e-04 -6.023153e-04 -6.310187e-04
## ASV2030     -1.151763e-03 -1.201490e-03 -1.253295e-03 -1.307273e-03
## ASV0300      8.701383e-04  9.111545e-04  9.540607e-04  9.989380e-04
## ASV1150      2.123083e-04  2.237196e-04  2.357598e-04  2.484625e-04
## ASV0958      2.698078e-03  2.826421e-03  2.960835e-03  3.101603e-03
## ASV0216     -2.814501e-03 -2.933834e-03 -3.057718e-03 -3.186297e-03
## ASV0446      4.395862e-03  4.594742e-03  4.802130e-03  5.018348e-03
## ASV0367     -2.850345e-03 -2.976801e-03 -3.108485e-03 -3.245582e-03
## ASV0200     -1.692557e-03 -1.767327e-03 -1.845151e-03 -1.926132e-03
## ASV0334     -8.063525e-04 -8.323395e-04 -8.586385e-04 -8.852092e-04
## ASV1311      1.014038e-03  1.050084e-03  1.086856e-03  1.124315e-03
## ASV0458      1.482861e-03  1.534387e-03  1.586888e-03  1.640310e-03
## ASV1371      2.865023e-04  3.008043e-04  3.158079e-04  3.315432e-04
## ASV0418      3.614862e-03  3.760906e-03  3.911814e-03  4.067670e-03
## ASV0004      5.210096e-04  5.417695e-04  5.631934e-04  5.852898e-04
## ASV1943      9.359499e-03  9.679356e-03  1.000529e-02  1.033704e-02
## ASV1495     -9.296401e-04 -9.864063e-04 -1.046858e-03 -1.111239e-03
## ASV0901     -3.259130e-03 -3.409067e-03 -3.565695e-03 -3.729299e-03
## ASV0628      1.586097e-03  1.646094e-03  1.707680e-03  1.770840e-03
## ASV0400      9.963513e-04  1.036962e-03  1.078921e-03  1.122247e-03
## ASV0116     -9.560329e-04 -9.997814e-04 -1.045458e-03 -1.093143e-03
## ASV0788      8.471575e-03  8.861099e-03  9.267951e-03  9.692855e-03
## ASV0117      6.415523e-04  6.725232e-04  7.049840e-04  7.390038e-04
## ASV3137     -1.879649e-04 -1.956898e-04 -2.036803e-04 -2.119408e-04
## ASV0001      5.562024e-04  5.780521e-04  6.005691e-04  6.237587e-04
## ASV1651      1.600275e-03  1.664618e-03  1.731072e-03  1.799669e-03
## ASV1692      7.040771e-03  7.363036e-03  7.699480e-03  8.050679e-03
## ASV0660      2.278172e-03  2.361639e-03  2.447022e-03  2.534257e-03
## ASV0508      1.116564e-04  1.155429e-04  1.195055e-04  1.235406e-04
## ASV1660     -1.493603e-03 -1.568204e-03 -1.646546e-03 -1.728808e-03
## ASV0233      2.135254e-03  2.229529e-03  2.327663e-03  2.429791e-03
## ASV1343     -3.998485e-03 -4.180583e-03 -4.370631e-03 -4.568948e-03
## ASV0209      1.864014e-03  1.937587e-03  2.013438e-03  2.091587e-03
## ASV0193     -2.190838e-03 -2.278562e-03 -2.369097e-03 -2.462473e-03
## ASV0357      9.767194e-04  1.028781e-03  1.083785e-03  1.141906e-03
## ASV0198      1.703116e-03  1.775107e-03  1.849787e-03  1.927231e-03
## ASV0007      4.837577e-04  5.020875e-04  5.209144e-04  5.402359e-04
## ASV1772     -6.965815e-04 -7.202087e-04 -7.440968e-04 -7.681830e-04
## ASV0009      3.931812e-04  4.074690e-04  4.220860e-04  4.370237e-04
## ASV0006     -4.888521e-04 -5.122599e-04 -5.367804e-04 -5.624644e-04
## ASV0011     -1.641386e-03 -1.715409e-03 -1.792593e-03 -1.873058e-03
## ASV0015      2.967676e-04  3.074990e-04  3.184698e-04  3.296725e-04
## ASV0017      3.350388e-04  3.472441e-04  3.597348e-04  3.725046e-04
## ASV0235     -1.524690e-03 -1.594106e-03 -1.666533e-03 -1.742088e-03
## ASV0382      1.190052e-03  1.243604e-03  1.299365e-03  1.357402e-03
## ASV2357      4.939762e-03  5.162256e-03  5.394256e-03  5.636131e-03
## ASV0567     -9.670926e-04 -1.011752e-03 -1.058448e-03 -1.107274e-03
## ASV0165      8.232870e-04  8.602177e-04  8.986999e-04  9.387894e-04
## ASV0005      1.171200e-03  1.221701e-03  1.274154e-03  1.328616e-03
## ASV0384     -7.262910e-05 -7.076857e-05 -6.838442e-05 -6.541988e-05
## ASV0002      2.132785e-04  2.219993e-04  2.310247e-04  2.403618e-04
## ASV3017      6.007023e-03  6.248783e-03  6.498440e-03  6.756110e-03
## ASV0091     -1.555810e-04 -1.622372e-04 -1.691638e-04 -1.763723e-04
## ASV0186     -2.373061e-03 -2.476453e-03 -2.583926e-03 -2.695607e-03
## ASV0370      1.237053e-03  1.289054e-03  1.342952e-03  1.398795e-03
## ASV0018      1.504925e-03  1.570232e-03  1.638101e-03  1.708611e-03
## ASV1377      1.468787e-02  1.529023e-02  1.591332e-02  1.655756e-02
## ASV0019      1.580258e-03  1.648970e-03  1.720392e-03  1.794608e-03
## ASV0023     -1.013280e-03 -1.059610e-03 -1.107965e-03 -1.158422e-03
## ASV2194      1.648241e-03  1.725523e-03  1.806382e-03  1.890978e-03
## ASV1155      6.143510e-03  6.396751e-03  6.659055e-03  6.930656e-03
## ASV0510     -1.570095e-03 -1.627509e-03 -1.686292e-03 -1.746420e-03
## ASV2371     -3.698843e-03 -3.850959e-03 -4.008441e-03 -4.171413e-03
## ASV0024     -1.258158e-03 -1.315379e-03 -1.375075e-03 -1.437342e-03
## ASV2452      3.601464e-03  3.738383e-03  3.879013e-03  4.023329e-03
## ASV2332     -1.071194e-02 -1.116067e-02 -1.162597e-02 -1.210830e-02
## ASV2591      3.137474e-03  3.296966e-03  3.464468e-03  3.640344e-03
## ASV0521      2.554054e-03  2.670129e-03  2.791239e-03  2.917584e-03
## ASV5542      2.442170e-03  2.552411e-03  2.667296e-03  2.786991e-03
## ASV0336     -3.686800e-04 -3.906085e-04 -4.138933e-04 -4.386160e-04
## ASV10102     4.509418e-03  4.713282e-03  4.925834e-03  5.147395e-03
## ASV16823    -6.496474e-03 -6.751476e-03 -7.014479e-03 -7.285594e-03
## ASV3104      3.360256e-02  3.492109e-02  3.628096e-02  3.768272e-02
## ASV0781      4.919130e-03  5.132218e-03  5.353682e-03  5.583786e-03
## ASV10899     3.202454e-03  3.369042e-03  3.544535e-03  3.729406e-03
## ASV11222    -1.142902e-02 -1.187745e-02 -1.233994e-02 -1.281669e-02
## ASV11327    -1.025770e-02 -1.066003e-02 -1.107497e-02 -1.150269e-02
## ASV12458    -1.142114e-02 -1.186895e-02 -1.233078e-02 -1.280682e-02
## ASV1636      6.633065e-03  6.908280e-03  7.193270e-03  7.488259e-03
## ASV1890     -5.083325e-03 -5.267828e-03 -5.456897e-03 -5.650496e-03
## ASV2898      8.903991e-03  9.274502e-03  9.658279e-03  1.005563e-02
## ASV8328      1.561543e-03  1.672752e-03  1.791973e-03  1.919751e-03
## ASV0709     -1.004559e-02 -1.047372e-02 -1.091795e-02 -1.137872e-02
## ASV0856      8.721072e-03  9.127301e-03  9.551855e-03  9.995494e-03
## ASV0909      2.820334e-03  2.978307e-03  3.145541e-03  3.322576e-03
## ASV0937     -6.079205e-03 -6.355477e-03 -6.643882e-03 -6.944925e-03
## ASV11390    -1.629643e-02 -1.693531e-02 -1.759418e-02 -1.827332e-02
## ASV11966     4.349961e-03  4.559068e-03  4.778054e-03  5.007353e-03
## ASV12990     2.901582e-03  3.019607e-03  3.141570e-03  3.267535e-03
## ASV14797     4.262822e-03  4.433564e-03  4.609854e-03  4.791779e-03
## ASV14904    -2.338351e-02 -2.430021e-02 -2.524560e-02 -2.622009e-02
## ASV15304     2.813003e-03  2.955467e-03  3.105169e-03  3.262458e-03
## ASV16696    -8.077585e-03 -8.394194e-03 -8.720711e-03 -9.057273e-03
## ASV1690      1.483802e-02  1.552871e-02  1.625015e-02  1.700354e-02
## ASV2029      9.848778e-03  1.026706e-02  1.070112e-02  1.115140e-02
## ASV2834      1.264532e-02  1.320952e-02  1.379722e-02  1.440924e-02
## ASV4003      1.085440e-02  1.138167e-02  1.193473e-02  1.251485e-02
## ASV4064      6.037404e-03  6.309858e-03  6.593877e-03  6.889888e-03
## ASV4294      3.898399e-03  4.097128e-03  4.306212e-03  4.526187e-03
## ASV4609      3.316232e-03  3.455536e-03  3.599958e-03  3.749635e-03
## ASV6283     -7.552913e-03 -7.849113e-03 -8.154601e-03 -8.469507e-03
## ASV6491     -1.082194e-02 -1.124620e-02 -1.168374e-02 -1.213477e-02
## ASV7453      5.796416e-03  6.077422e-03  6.371882e-03  6.680398e-03
## ASV7959      2.257749e-03  2.382276e-03  2.513903e-03  2.653028e-03
## ASV8219      9.351345e-02  9.717945e-02  1.009603e-01  1.048578e-01
## ASV8547     -9.684417e-03 -1.006394e-02 -1.045535e-02 -1.085882e-02
## ASV9319      4.561305e-03  4.772773e-03  4.993736e-03  5.224591e-03
## ASV9382     -1.894555e-02 -1.968793e-02 -2.045355e-02 -2.124275e-02
## ASV11516    -1.264975e-02 -1.314526e-02 -1.365627e-02 -1.418300e-02
## ASV14377    -9.130662e-03 -9.488197e-03 -9.856911e-03 -1.023696e-02
## ASV1867      7.555766e-03  7.897372e-03  8.253608e-03  8.625030e-03
## ASV1895      3.519597e-03  3.652601e-03  3.789041e-03  3.928865e-03
## ASV3168      4.516623e-03  4.696275e-03  4.881536e-03  5.072455e-03
## ASV4449      2.577581e-02  2.689448e-02  2.805779e-02  2.926727e-02
## ASV6596      5.743617e-03  6.028148e-03  6.326977e-03  6.640819e-03
## ASV7492     -6.305623e-04 -6.264238e-04 -6.195994e-04 -6.098143e-04
## ASV9854     -1.929792e-03 -2.003571e-03 -2.079559e-03 -2.157785e-03
## ASV6296      1.531578e-01  1.591532e-01  1.653360e-01  1.717086e-01
## ASV4201      1.145797e-03  1.229879e-03  1.320152e-03  1.417044e-03
## ASV0552      5.208893e-03  5.442541e-03  5.686026e-03  5.939708e-03
## ASV3671     -3.386192e-03 -3.531574e-03 -3.682786e-03 -3.840048e-03
## ASV3529     -6.157282e-04 -6.182818e-04 -6.191269e-04 -6.180907e-04
## ASV1060      1.422778e-03  1.490323e-03  1.561078e-03  1.635196e-03
## ASV0239     -1.739900e-03 -1.805831e-03 -1.873582e-03 -1.943149e-03
## ASV5711     -8.209452e-03 -8.553700e-03 -8.910715e-03 -9.280859e-03
## ASV4152     -1.188414e-02 -1.240731e-02 -1.295184e-02 -1.351849e-02
## ASV1461      5.648666e-03  5.865673e-03  6.088882e-03  6.318304e-03
## ASV2877      2.961152e-03  3.077369e-03  3.197100e-03  3.320366e-03
## ASV0012      5.351725e-04  5.585588e-04  5.828855e-04  6.081846e-04
## ASV9823      6.377084e-04  6.537097e-04  6.692720e-04  6.842835e-04
## ASV0008      5.678195e-04  5.923609e-04  6.178688e-04  6.443745e-04
## ASV7832     -7.034339e-03 -7.348227e-03 -7.675402e-03 -8.016375e-03
## ASV1915     -8.579201e-04 -8.935503e-04 -9.305639e-04 -9.690165e-04
## ASV0055     -6.692169e-04 -7.034121e-04 -7.394015e-04 -7.772791e-04
## ASV0032      2.519706e-04  2.599578e-04  2.680183e-04  2.761359e-04
## ASV2977     -9.828016e-03 -1.025761e-02 -1.070446e-02 -1.116917e-02
## ASV0466      7.482403e-03  7.770782e-03  8.067493e-03  8.372558e-03
## ASV3866      5.523313e-03  5.776215e-03  6.040264e-03  6.315916e-03
## ASV0040      1.966858e-03  2.054288e-03  2.145349e-03  2.240171e-03
## ASV0496     -6.367500e-04 -6.806484e-04 -7.276596e-04 -7.779941e-04
## ASV0052      1.653086e-03  1.726711e-03  1.803401e-03  1.883268e-03
## ASV3828     -5.411132e-03 -5.621650e-03 -5.838632e-03 -6.062154e-03
## ASV1930      2.837368e-03  2.952729e-03  3.071908e-03  3.194957e-03
## ASV2126      4.923948e-03  5.133316e-03  5.350599e-03  5.576023e-03
## ASV0793      6.231773e-03  6.514551e-03  6.809527e-03  7.117175e-03
## ASV0299     -1.318721e-04 -1.391418e-04 -1.469107e-04 -1.552232e-04
## ASV0208      4.452839e-03  4.650821e-03  4.857053e-03  5.071839e-03
## ASV0511     -1.701632e-03 -1.765158e-03 -1.830316e-03 -1.897093e-03
## ASV1123     -5.198399e-03 -5.398109e-03 -5.603611e-03 -5.814935e-03
## ASV0099      1.882081e-04  1.987303e-04  2.098973e-04  2.217521e-04
## ASV0752     -3.265215e-03 -3.418962e-03 -3.579788e-03 -3.748002e-03
## ASV0883      4.461703e-03  4.670152e-03  4.888046e-03  5.115779e-03
## ASV0683      5.785417e-03  6.051689e-03  6.329755e-03  6.620096e-03
## ASV4117     -9.055664e-03 -9.458858e-03 -9.879004e-03 -1.031675e-02
## ASV2172      5.079099e-04  5.229384e-04  5.379360e-04  5.528472e-04
## ASV0330     -1.704201e-03 -1.781088e-03 -1.861272e-03 -1.944881e-03
## ASV0728      8.272298e-03  8.631171e-03  9.004116e-03  9.391565e-03
## ASV0499      2.259620e-03  2.364463e-03  2.474035e-03  2.588535e-03
## ASV0120     -3.675983e-03 -3.836072e-03 -4.002479e-03 -4.175399e-03
## ASV1446      2.519378e-03  2.601527e-03  2.684675e-03  2.768675e-03
## ASV17171    -7.092823e-03 -7.402473e-03 -7.724687e-03 -8.059916e-03
## ASV0533      5.648927e-04  5.929038e-04  6.223179e-04  6.532038e-04
## ASV2495     -1.917928e-03 -2.018954e-03 -2.125591e-03 -2.238158e-03
## ASV5582      3.010919e-03  3.117032e-03  3.225294e-03  3.335614e-03
## ASV1488      1.212455e-03  1.261193e-03  1.311477e-03  1.363320e-03
## ASV0682      1.653891e-03  1.731261e-03  1.812159e-03  1.896737e-03
## ASV0068     -2.795512e-03 -2.918349e-03 -3.046125e-03 -3.179001e-03
## ASV1987     -7.219797e-03 -7.561601e-03 -7.919287e-03 -8.293551e-03
## ASV0035     -6.286083e-04 -6.671342e-04 -7.082148e-04 -7.520266e-04
## ASV7192     -4.232869e-03 -4.410386e-03 -4.594420e-03 -4.785142e-03
## ASV0873     -2.411635e-03 -2.688984e-03 -2.990666e-03 -3.318399e-03
## ASV4749     -4.842073e-04 -5.377283e-04 -5.961534e-04 -6.598694e-04
## ASV2174      2.779618e-03  2.880343e-03  2.983342e-03  3.088546e-03
## ASV1476     -3.178742e-03 -3.327868e-03 -3.483924e-03 -3.647226e-03
## ASV0740     -8.996098e-03 -9.414277e-03 -9.851394e-03 -1.030826e-02
## ASV0170     -1.717792e-03 -1.793688e-03 -1.872699e-03 -1.954934e-03
## ASV2466     -7.840706e-03 -8.188548e-03 -8.550883e-03 -8.928246e-03
## ASV1709      2.782353e-03  2.898308e-03  3.018691e-03  3.143663e-03
## ASV6170     -1.245184e-02 -1.301987e-02 -1.361273e-02 -1.423142e-02
## ASV3673      6.169804e-03  6.456312e-03  6.755755e-03  7.068680e-03
## ASV1745     -1.650131e-03 -1.731563e-03 -1.817058e-03 -1.906818e-03
##                                                                    
## (Intercept)  4.949806e-02  5.164344e-02  5.387245e-02  5.618758e-02
## ASV1236      9.398448e-03  9.777588e-03  1.016947e-02  1.057435e-02
## ASV0421      1.344972e-03  1.421277e-03  1.502020e-03  1.587444e-03
## ASV0691     -6.784401e-03 -7.016100e-03 -7.252180e-03 -7.492464e-03
## ASV0899      8.171141e-03  8.501139e-03  8.841997e-03  9.193874e-03
## ASV1004      1.886935e-02  1.963304e-02  2.042236e-02  2.123778e-02
## ASV1041     -7.696704e-03 -8.001359e-03 -8.315375e-03 -8.638811e-03
## ASV1058      1.176019e-02  1.223533e-02  1.272643e-02  1.323381e-02
## ASV12542     4.455698e-03  4.627585e-03  4.804606e-03  4.986816e-03
## ASV1294      1.096202e-02  1.140630e-02  1.186563e-02  1.234030e-02
## ASV13113     4.019095e-03  4.211549e-03  4.413182e-03  4.624424e-03
## ASV1318      1.091708e-02  1.135807e-02  1.181381e-02  1.228457e-02
## ASV2269     -1.882277e-02 -1.957517e-02 -2.035181e-02 -2.115304e-02
## ASV2542      9.757638e-03  1.019703e-02  1.065519e-02  1.113287e-02
## ASV2660     -7.449543e-03 -7.744392e-03 -8.048554e-03 -8.362147e-03
## ASV2737      2.475237e-03  2.565520e-03  2.658110e-03  2.753003e-03
## ASV2840      9.677424e-03  1.003932e-02  1.041076e-02  1.079166e-02
## ASV3053      5.027628e-02  5.222585e-02  5.423439e-02  5.630255e-02
## ASV3077      3.222939e-03  3.349463e-03  3.479984e-03  3.614567e-03
## ASV3134      6.314076e-03  6.608695e-03  6.916778e-03  7.238913e-03
## ASV3140      8.216585e-03  8.572545e-03  8.942450e-03  9.326727e-03
## ASV3579      3.172547e-03  3.330912e-03  3.497270e-03  3.672016e-03
## ASV6119     -5.149673e-03 -5.355458e-03 -5.567873e-03 -5.787009e-03
## ASV7557     -1.046082e-02 -1.087865e-02 -1.130993e-02 -1.175484e-02
## ASV8422      2.572733e-03  2.673256e-03  2.776918e-03  2.883766e-03
## ASV1086     -3.668105e-04 -3.786054e-04 -3.905953e-04 -4.027749e-04
## ASV1310      5.026626e-03  5.228722e-03  5.437474e-03  5.652992e-03
## ASV15750    -6.389614e-04 -6.608707e-04 -6.831514e-04 -7.057755e-04
## ASV16905    -2.151092e-03 -2.237014e-03 -2.325701e-03 -2.417192e-03
## ASV2033      9.891101e-03  1.034260e-02  1.081368e-02  1.130512e-02
## ASV2089      4.540822e-03  4.722562e-03  4.910178e-03  5.103754e-03
## ASV2127      1.478236e-02  1.537797e-02  1.599340e-02  1.662900e-02
## ASV2725      1.163823e-02  1.209235e-02  1.256032e-02  1.304231e-02
## ASV2804     -4.452315e-03 -4.630144e-03 -4.813699e-03 -5.003057e-03
## ASV3075      1.012290e-02  1.055880e-02  1.101196e-02  1.148299e-02
## ASV3327      1.433203e-02  1.497161e-02  1.563784e-02  1.633171e-02
## ASV3342      1.223676e-02  1.277723e-02  1.333988e-02  1.392549e-02
## ASV3532     -1.334427e-02 -1.392230e-02 -1.452323e-02 -1.514784e-02
## ASV3600      6.232456e-03  6.504583e-03  6.787642e-03  7.082001e-03
## ASV4013      1.134687e-02  1.182025e-02  1.231073e-02  1.281872e-02
## ASV4136      1.173169e-02  1.219431e-02  1.267165e-02  1.316394e-02
## ASV4195      4.543014e-02  4.724391e-02  4.911604e-02  5.104731e-02
## ASV4407     -1.754588e-02 -1.824607e-02 -1.896876e-02 -1.971426e-02
## ASV4717      2.875397e-03  2.977193e-03  3.081308e-03  3.187711e-03
## ASV6794      7.093298e-03  7.364496e-03  7.643705e-03  7.931010e-03
## ASV8324     -9.003181e-03 -9.362453e-03 -9.733266e-03 -1.011578e-02
## ASV8981     -9.285767e-05 -8.604544e-05 -7.804540e-05 -6.874533e-05
## ASV9859      3.639690e-03  3.827310e-03  4.024972e-03  4.233226e-03
## ASV0936      9.226737e-03  9.633215e-03  1.005611e-02  1.049595e-02
## ASV12683    -4.848117e-05 -5.309290e-05 -5.803077e-05 -6.330776e-05
## ASV1293      5.831739e-03  6.064149e-03  6.304057e-03  6.551575e-03
## ASV13055    -4.253619e-05 -3.655953e-05 -2.968837e-05 -2.184186e-05
## ASV17063    -4.665168e-03 -4.851077e-03 -5.042942e-03 -5.240845e-03
## ASV2228      3.803043e-03  3.954527e-03  4.110860e-03  4.272105e-03
## ASV2769      7.398388e-04  7.802091e-04  8.228041e-04  8.677359e-04
## ASV2803      3.973643e-03  4.121545e-03  4.273388e-03  4.429167e-03
## ASV2896      3.526248e-03  3.686241e-03  3.853265e-03  4.027620e-03
## ASV3062      4.459717e-03  4.675988e-03  4.902678e-03  5.140262e-03
## ASV3107      6.498853e-03  6.787304e-03  7.087774e-03  7.400707e-03
## ASV3265      8.318282e-03  8.647653e-03  8.987448e-03  9.337805e-03
## ASV3666      6.330812e-05  6.426798e-05  6.509429e-05  6.576671e-05
## ASV4497      2.900287e-03  3.018529e-03  3.140822e-03  3.267252e-03
## ASV6914     -5.202666e-04 -5.481507e-04 -5.775602e-04 -6.085742e-04
## ASV0576     -9.528860e-03 -9.876662e-03 -1.023312e-02 -1.059816e-02
## ASV0673      1.126370e-02  1.172969e-02  1.221217e-02  1.271153e-02
## ASV0772      5.280814e-03  5.503826e-03  5.735197e-03  5.975168e-03
## ASV0862      8.661040e-04  9.292374e-04  9.968567e-04  1.069242e-03
## ASV0898      4.331665e-03  4.531273e-03  4.739637e-03  4.957092e-03
## ASV0910      4.899474e-03  5.118815e-03  5.347410e-03  5.585606e-03
## ASV0964     -3.651616e-03 -3.788373e-03 -3.928795e-03 -4.072871e-03
## ASV10059     3.613169e-03  3.784284e-03  3.963365e-03  4.150761e-03
## ASV10263    -7.118503e-03 -7.403046e-03 -7.696789e-03 -7.999865e-03
## ASV1088      8.658807e-03  9.041936e-03  9.441048e-03  9.856750e-03
## ASV1101      1.014236e-02  1.054524e-02  1.096095e-02  1.138966e-02
## ASV1183      2.804412e-03  2.925569e-03  3.051483e-03  3.182306e-03
## ASV11956     2.476578e-03  2.566373e-03  2.658384e-03  2.752596e-03
## ASV12774     3.963673e-05  3.259501e-05  2.456898e-05  1.547541e-05
## ASV1321      1.275937e-02  1.333845e-02  1.394255e-02  1.457264e-02
## ASV13793    -4.907176e-03 -5.103258e-03 -5.305673e-03 -5.514510e-03
## ASV14482     2.790235e-04  2.881197e-04  2.974108e-04  3.069003e-04
## ASV15483     2.139924e-03  2.234887e-03  2.333758e-03  2.436669e-03
## ASV2062      9.605961e-03  1.000612e-02  1.042080e-02  1.085038e-02
## ASV2132      8.117308e-03  8.475882e-03  8.849119e-03  9.237521e-03
## ASV2413      7.315069e-03  7.611467e-03  7.917947e-03  8.234719e-03
## ASV2490      2.193753e-02  2.278171e-02  2.365076e-02  2.454488e-02
## ASV2594      2.934533e-03  3.063347e-03  3.197505e-03  3.337214e-03
## ASV2822     -1.296012e-02 -1.347870e-02 -1.401412e-02 -1.456660e-02
## ASV2863      1.365950e-02  1.419830e-02  1.475423e-02  1.532755e-02
## ASV2910      5.036847e-03  5.238073e-03  5.445860e-03  5.660316e-03
## ASV2980      5.759764e-03  6.000500e-03  6.249985e-03  6.508438e-03
## ASV3307      1.030494e-02  1.071688e-02  1.114216e-02  1.158095e-02
## ASV3474      7.384383e-03  7.725084e-03  8.080921e-03  8.452507e-03
## ASV3502      7.422458e-03  7.740908e-03  8.071677e-03  8.415148e-03
## ASV4236      1.023208e-02  1.061855e-02  1.101565e-02  1.142337e-02
## ASV4842     -1.208727e-03 -1.261699e-03 -1.316601e-03 -1.373457e-03
## ASV4894     -4.911458e-03 -5.107978e-03 -5.310875e-03 -5.520245e-03
## ASV5290      4.101000e-03  4.280640e-03  4.467477e-03  4.661745e-03
## ASV5501      2.483702e-03  2.591788e-03  2.704312e-03  2.821449e-03
## ASV5795      2.766351e-03  2.888416e-03  3.015458e-03  3.147647e-03
## ASV5987     -1.372340e-02 -1.427287e-02 -1.484022e-02 -1.542570e-02
## ASV6267     -1.545776e-02 -1.607639e-02 -1.671512e-02 -1.737425e-02
## ASV6862      6.087101e-03  6.322631e-03  6.565275e-03  6.815112e-03
## ASV7145      2.647449e-03  2.747785e-03  2.851120e-03  2.957505e-03
## ASV7673     -4.911055e-03 -5.107574e-03 -5.310475e-03 -5.519854e-03
## ASV7789      2.803329e-03  2.945119e-03  3.094228e-03  3.251032e-03
## ASV7809      3.021362e-04  3.248300e-04  3.491782e-04  3.752874e-04
## ASV8002     -6.202753e-03 -6.451030e-03 -6.707382e-03 -6.971933e-03
## ASV8205      2.721410e-03  2.840364e-03  2.964117e-03  3.092835e-03
## ASV9155     -1.538187e-03 -1.596666e-03 -1.656771e-03 -1.718499e-03
## ASV9221      8.832797e-04  9.383029e-04  9.968969e-04  1.059287e-03
## ASV9311     -9.949261e-03 -1.034752e-02 -1.075873e-02 -1.118311e-02
## ASV9557     -6.797040e-03 -7.068992e-03 -7.349785e-03 -7.639556e-03
## ASV9936     -1.370205e-02 -1.425003e-02 -1.481580e-02 -1.539963e-02
## ASV1445      8.726301e-03  9.107101e-03  9.503107e-03  9.914815e-03
## ASV4232      3.479610e-03  3.646053e-03  3.820515e-03  4.003387e-03
## ASV6479      1.469293e-03  1.555824e-03  1.647683e-03  1.745193e-03
## ASV0142     -5.866767e-03 -6.098664e-03 -6.337925e-03 -6.584656e-03
## ASV0378      2.955275e-03  3.095061e-03  3.241303e-03  3.394276e-03
## ASV1122      8.510691e-03  8.887120e-03  9.279017e-03  9.686923e-03
## ASV0123     -5.169510e-03 -5.372943e-03 -5.582755e-03 -5.799029e-03
## ASV2064      2.512902e-03  2.600800e-03  2.690404e-03  2.781628e-03
## ASV4459     -3.193640e-04 -3.282942e-04 -3.372535e-04 -3.462303e-04
## ASV0448      2.366173e-03  2.478302e-03  2.595630e-03  2.718382e-03
## ASV0397      4.882969e-03  5.089713e-03  5.304187e-03  5.526604e-03
## ASV0485      5.596866e-03  5.828152e-03  6.067669e-03  6.315614e-03
## ASV1566      8.333629e-03  8.684375e-03  9.048060e-03  9.425026e-03
## ASV1365      7.205130e-03  7.514675e-03  7.836073e-03  8.169657e-03
## ASV1065      1.022333e-02  1.066225e-02  1.111812e-02  1.159144e-02
## ASV0722     -5.600126e-04 -5.863943e-04 -6.140379e-04 -6.430072e-04
## ASV12660    -5.582183e-03 -5.800688e-03 -6.025995e-03 -6.258192e-03
## ASV0223      1.555024e-03  1.620113e-03  1.687608e-03  1.757578e-03
## ASV0229      2.459203e-03  2.568771e-03  2.682932e-03  2.801855e-03
## ASV0877      8.946104e-04  9.229934e-04  9.514773e-04  9.799637e-04
## ASV0983      5.516142e-03  5.740641e-03  5.972781e-03  6.212711e-03
## ASV0626      8.326884e-04  8.849120e-04  9.404269e-04  9.994197e-04
## ASV4146      2.559116e-04  2.640473e-04  2.720881e-04  2.799742e-04
## ASV4175     -7.089674e-03 -7.401297e-03 -7.725534e-03 -8.062811e-03
## ASV2082     -3.653862e-03 -3.851154e-03 -4.059611e-03 -4.279872e-03
## ASV2272      3.362536e-03  3.509832e-03  3.663130e-03  3.822644e-03
## ASV2245     -5.093086e-03 -5.319117e-03 -5.554460e-03 -5.799438e-03
## ASV0590     -3.567152e-03 -3.767213e-03 -3.978982e-03 -4.203139e-03
## ASV0217      5.822778e-04  6.318370e-04  6.852832e-04  7.428797e-04
## ASV0416      3.403228e-03  3.519286e-03  3.637367e-03  3.757342e-03
## ASV1056      5.004595e-03  5.232636e-03  5.470526e-03  5.718636e-03
## ASV7777     -6.864469e-03 -7.164190e-03 -7.476005e-03 -7.800337e-03
## ASV0455      1.218463e-03  1.270402e-03  1.324297e-03  1.380198e-03
## ASV0604      3.339497e-03  3.494983e-03  3.657441e-03  3.827154e-03
## ASV6100     -4.799094e-03 -5.014063e-03 -5.238166e-03 -5.471757e-03
## ASV11359    -1.015636e-02 -1.059756e-02 -1.105614e-02 -1.153265e-02
## ASV6604      1.461243e-03  1.528783e-03  1.599319e-03  1.672972e-03
## ASV5004     -3.586004e-03 -3.740187e-03 -3.900392e-03 -4.066811e-03
## ASV1483     -1.530955e-03 -1.595575e-03 -1.662597e-03 -1.732085e-03
## ASV9773     -4.608856e-03 -4.812168e-03 -5.023832e-03 -5.244147e-03
## ASV4059      2.566355e-04  2.866744e-04  3.194370e-04  3.551254e-04
## ASV1193      5.456432e-03  5.688237e-03  5.928797e-03  6.178363e-03
## ASV4610     -5.370864e-04 -5.363501e-04 -5.338280e-04 -5.293539e-04
## ASV0742     -2.412012e-04 -2.306012e-04 -2.179551e-04 -2.030870e-04
## ASV1502     -4.247508e-04 -4.564745e-04 -4.905072e-04 -5.269983e-04
## ASV0195      2.638746e-05  1.961849e-05  1.197403e-05  3.383992e-06
## ASV1213      3.574246e-03  3.705569e-03  3.840195e-03  3.978093e-03
## ASV1648     -4.303009e-03 -4.495403e-03 -4.695975e-03 -4.905046e-03
## ASV6984     -4.032342e-03 -4.213234e-03 -4.401881e-03 -4.598594e-03
## ASV0396     -1.072028e-04 -1.035161e-04 -9.910463e-05 -9.391593e-05
## ASV4297      5.293459e-03  5.496575e-03  5.705569e-03  5.920471e-03
## ASV2622      8.416076e-03  8.755817e-03  9.106955e-03  9.469708e-03
## ASV3512      3.762041e-03  3.953264e-03  4.154493e-03  4.366258e-03
## ASV2411      6.172997e-03  6.456907e-03  6.753373e-03  7.062902e-03
## ASV2291     -3.136080e-03 -3.314861e-03 -3.504209e-03 -3.704729e-03
## ASV0807      8.037640e-03  8.378702e-03  8.732520e-03  9.099432e-03
## ASV1292      1.752934e-03  1.813302e-03  1.874828e-03  1.937462e-03
## ASV1035      7.102844e-03  7.385343e-03  7.677088e-03  7.978251e-03
## ASV0070      1.852443e-04  2.026278e-04  2.214853e-04  2.419268e-04
## ASV0255      6.292466e-04  6.502968e-04  6.716051e-04  6.931267e-04
## ASV0057     -1.885056e-03 -1.954153e-03 -2.024943e-03 -2.097399e-03
## ASV0077     -3.549550e-04 -3.643064e-04 -3.735446e-04 -3.826315e-04
## ASV0625      4.042359e-03  4.198778e-03  4.359852e-03  4.525618e-03
## ASV2464      2.741970e-02  2.847880e-02  2.956988e-02  3.069329e-02
## ASV1315      8.088737e-03  8.464082e-03  8.856278e-03  9.266019e-03
## ASV2673      6.951222e-03  7.274798e-03  7.612991e-03  7.966414e-03
## ASV2161      2.931429e-03  3.067564e-03  3.209868e-03  3.358607e-03
## ASV0337     -1.631206e-03 -1.703302e-03 -1.778352e-03 -1.856460e-03
## ASV7680     -1.069096e-02 -1.116723e-02 -1.166337e-02 -1.218011e-02
## ASV0611      5.985768e-03  6.253828e-03  6.533229e-03  6.824401e-03
## ASV3118     -6.406779e-03 -6.707397e-03 -7.021746e-03 -7.350406e-03
## ASV1284      1.362388e-03  1.359423e-03  1.351155e-03  1.337002e-03
## ASV0889      4.311639e-03  4.489051e-03  4.672764e-03  4.862939e-03
## ASV4649     -2.225063e-03 -2.321455e-03 -2.421661e-03 -2.525807e-03
## ASV1108     -4.876798e-03 -5.112106e-03 -5.358727e-03 -5.617185e-03
## ASV0738      2.876635e-03  3.028445e-03  3.188546e-03  3.357390e-03
## ASV0473     -6.473436e-04 -6.848650e-04 -7.245391e-04 -7.664721e-04
## ASV0598     -1.539440e-03 -1.625608e-03 -1.716863e-03 -1.813510e-03
## ASV0429      3.128204e-03  3.250621e-03  3.376733e-03  3.506563e-03
## ASV1549      6.425751e-03  6.725754e-03  7.039378e-03  7.367200e-03
## ASV1203      4.704373e-03  4.898397e-03  5.099239e-03  5.307050e-03
## ASV4532      1.532701e-04  1.563099e-04  1.592457e-04  1.620667e-04
## ASV0274      9.221057e-04  9.676032e-04  1.015284e-03  1.065237e-03
## ASV0163     -3.499966e-03 -3.634911e-03 -3.773906e-03 -3.916995e-03
## ASV1298      3.398217e-04  3.503385e-04  3.610651e-04  3.720125e-04
## ASV9424     -8.346218e-03 -8.723031e-03 -9.116076e-03 -9.525996e-03
## ASV0412      8.104472e-03  8.434983e-03  8.776867e-03  9.130365e-03
## ASV0284      1.507210e-03  1.554309e-03  1.601768e-03  1.649481e-03
## ASV0620     -1.965939e-03 -2.069236e-03 -2.178089e-03 -2.292791e-03
## ASV0153     -8.583171e-03 -8.982957e-03 -9.400764e-03 -9.837338e-03
## ASV0498      2.939151e-03  3.069106e-03  3.204287e-03  3.344854e-03
## ASV0097      1.686838e-03  1.765580e-03  1.847902e-03  1.933956e-03
## ASV0104     -1.119718e-02 -1.166730e-02 -1.215460e-02 -1.265950e-02
## ASV1282      3.697608e-03  3.840009e-03  3.986430e-03  4.136857e-03
## ASV3883     -3.411039e-03 -3.579443e-03 -3.756107e-03 -3.941408e-03
## ASV0801      1.567852e-03  1.637545e-03  1.710138e-03  1.785738e-03
## ASV1611     -7.563660e-03 -7.910579e-03 -8.272805e-03 -8.650958e-03
## ASV0227     -1.570190e-03 -1.656467e-03 -1.747620e-03 -1.843914e-03
## ASV0833      2.508966e-03  2.619206e-03  2.733883e-03  2.853141e-03
## ASV0718      1.118132e-02  1.167086e-02  1.218015e-02  1.270984e-02
## ASV1139      1.108187e-03  1.132006e-03  1.154731e-03  1.176168e-03
## ASV0766     -1.700993e-03 -1.785169e-03 -1.873473e-03 -1.966095e-03
## ASV2091      8.496710e-03  8.825672e-03  9.164378e-03  9.512893e-03
## ASV1238     -8.495417e-03 -8.882182e-03 -9.286017e-03 -9.707649e-03
## ASV9193     -1.085515e-03 -1.154741e-03 -1.228634e-03 -1.307509e-03
## ASV0290      9.911143e-04  1.021062e-03  1.051239e-03  1.081597e-03
## ASV0231      3.186197e-03  3.315560e-03  3.449284e-03  3.587446e-03
## ASV0185      2.196526e-03  2.311785e-03  2.433298e-03  2.561403e-03
## ASV2330      3.493736e-03  3.624021e-03  3.757763e-03  3.894951e-03
## ASV3119     -1.971522e-03 -2.073682e-03 -2.181273e-03 -2.294580e-03
## ASV2368     -4.468295e-03 -4.679522e-03 -4.900693e-03 -5.132273e-03
## ASV0122     -2.005472e-03 -2.088925e-03 -2.175390e-03 -2.264943e-03
## ASV1044      5.453115e-03  5.703549e-03  5.965068e-03  6.238128e-03
## ASV0160     -2.041100e-03 -2.117905e-03 -2.196831e-03 -2.277883e-03
## ASV0326      5.884573e-04  6.141724e-04  6.408863e-04  6.686253e-04
## ASV1388      1.044372e-02  1.088047e-02  1.133306e-02  1.180187e-02
## ASV0792      7.539048e-03  7.838992e-03  8.148550e-03  8.467856e-03
## ASV0036     -2.575270e-03 -2.695079e-03 -2.820250e-03 -2.950998e-03
## ASV2125      7.524034e-03  7.843020e-03  8.173932e-03  8.517088e-03
## ASV1075     -1.164158e-04 -1.218499e-04 -1.275694e-04 -1.335944e-04
## ASV0390      4.261743e-03  4.461684e-03  4.670868e-03  4.889710e-03
## ASV3790     -5.858607e-03 -6.119208e-03 -6.390662e-03 -6.673365e-03
## ASV1535     -1.861168e-03 -1.956381e-03 -2.056553e-03 -2.161937e-03
## ASV0263      7.059813e-03  7.365280e-03  7.682750e-03  8.012601e-03
## ASV0675      1.089709e-02  1.139008e-02  1.190426e-02  1.244044e-02
## ASV3348      9.357670e-04  9.817567e-04  1.029994e-03  1.080582e-03
## ASV0058     -3.077376e-03 -3.205199e-03 -3.337579e-03 -3.474618e-03
## ASV4142      4.195032e-03  4.359982e-03  4.530018e-03  4.705194e-03
## ASV0059     -2.458204e-03 -2.558742e-03 -2.662727e-03 -2.770227e-03
## ASV0013     -4.495359e-03 -4.688897e-03 -4.889944e-03 -5.098729e-03
## ASV0033     -2.230017e-03 -2.333217e-03 -2.441003e-03 -2.553557e-03
## ASV4354     -2.662535e-03 -2.778951e-03 -2.900132e-03 -3.026256e-03
## ASV0022     -1.881547e-03 -1.968567e-03 -2.059457e-03 -2.154376e-03
## ASV0134     -1.860764e-03 -1.952051e-03 -2.047842e-03 -2.148355e-03
## ASV0415      3.387987e-04  3.576629e-04  3.775512e-04  3.985098e-04
## ASV10103    -1.030200e-02 -1.076846e-02 -1.125500e-02 -1.176238e-02
## ASV1613      7.150349e-03  7.434493e-03  7.727627e-03  8.029854e-03
## ASV0135     -8.804520e-04 -9.124970e-04 -9.453014e-04 -9.788507e-04
## ASV0469     -9.399927e-03 -9.788350e-03 -1.019066e-02 -1.060722e-02
## ASV0471      5.844069e-03  6.094392e-03  6.354349e-03  6.624231e-03
## ASV0451     -1.182317e-03 -1.249812e-03 -1.321292e-03 -1.396987e-03
## ASV0747      3.375022e-03  3.523040e-03  3.676999e-03  3.837091e-03
## ASV1314     -3.543409e-03 -3.711008e-03 -3.886461e-03 -4.070126e-03
## ASV0425     -1.134822e-02 -1.179441e-02 -1.225451e-02 -1.272869e-02
## ASV0559     -2.934731e-03 -3.061104e-03 -3.192557e-03 -3.329280e-03
## ASV0148     -5.124267e-04 -5.226153e-04 -5.321781e-04 -5.410104e-04
## ASV0129      9.841043e-04  1.049087e-03  1.118550e-03  1.192792e-03
## ASV1072      6.882432e-04  7.099019e-04  7.316994e-04  7.535793e-04
## ASV2390      5.669948e-03  5.880626e-03  6.096626e-03  6.317876e-03
## ASV0548      4.005484e-03  4.175680e-03  4.352276e-03  4.535445e-03
## ASV0168     -2.014853e-03 -2.097500e-03 -2.183034e-03 -2.271518e-03
## ASV0066     -2.288324e-03 -2.383281e-03 -2.481594e-03 -2.583335e-03
## ASV0468     -1.244728e-03 -1.299134e-03 -1.355742e-03 -1.414630e-03
## ASV0172     -6.043362e-04 -6.231388e-04 -6.420570e-04 -6.610440e-04
## ASV0236      2.406337e-04  2.789475e-04  3.210779e-04  3.673252e-04
## ASV0250      3.627582e-03  3.809767e-03  4.001293e-03  4.202641e-03
## ASV0338      1.630972e-03  1.705747e-03  1.783699e-03  1.864931e-03
## ASV0450     -3.749236e-04 -3.973392e-04 -4.211586e-04 -4.464692e-04
## ASV0377      2.850704e-03  2.968542e-03  3.090528e-03  3.216749e-03
## ASV1022     -1.043441e-04 -1.070164e-04 -1.095867e-04 -1.120283e-04
## ASV6174     -1.074789e-04 -1.156927e-04 -1.245622e-04 -1.341371e-04
## ASV0786     -5.560989e-04 -5.908377e-04 -6.277570e-04 -6.669808e-04
## ASV0053     -3.170682e-03 -3.308426e-03 -3.451609e-03 -3.600400e-03
## ASV0697     -1.841361e-03 -1.915200e-03 -1.991498e-03 -2.070304e-03
## ASV0785      3.952990e-03  4.116810e-03  4.286454e-03  4.462058e-03
## ASV1967     -3.899040e-03 -4.059199e-03 -4.225033e-03 -4.396683e-03
## ASV0385      1.431512e-03  1.498862e-03  1.569242e-03  1.642767e-03
## ASV0295      3.559134e-04  3.801744e-04  4.061464e-04  4.339459e-04
## ASV0072     -3.018505e-03 -3.139274e-03 -3.263924e-03 -3.392503e-03
## ASV0157     -2.237589e-04 -2.197867e-04 -2.144695e-04 -2.076641e-04
## ASV0501      6.873026e-03  7.173440e-03  7.485823e-03  7.810553e-03
## ASV10729    -8.713992e-03 -9.101142e-03 -9.504346e-03 -9.924178e-03
## ASV1470      4.023079e-03  4.170932e-03  4.322425e-03  4.477504e-03
## ASV0050     -7.252671e-03 -7.554706e-03 -7.867570e-03 -8.191518e-03
## ASV0411     -1.736409e-03 -1.816483e-03 -1.900125e-03 -1.987485e-03
## ASV0549      2.753653e-03  2.877774e-03  3.007174e-03  3.142048e-03
## ASV0184      8.847727e-04  9.223476e-04  9.613837e-04  1.001932e-03
## ASV0705      1.703211e-03  1.771200e-03  1.841348e-03  1.913676e-03
## ASV1715      3.761359e-03  3.924292e-03  4.093622e-03  4.269549e-03
## ASV0603      6.127678e-04  6.417405e-04  6.721224e-04  7.039886e-04
## ASV0826      6.259863e-03  6.524504e-03  6.799036e-03  7.083735e-03
## ASV0034     -1.957615e-03 -2.036641e-03 -2.118284e-03 -2.202587e-03
## ASV0838      9.808645e-04  9.904195e-04  9.974045e-04  1.001476e-03
## ASV0614     -1.711054e-03 -1.783221e-03 -1.858074e-03 -1.935689e-03
## ASV0014     -4.559468e-03 -4.753336e-03 -4.954513e-03 -5.163202e-03
## ASV0585      2.024612e-04  1.882321e-04  1.715586e-04  1.522200e-04
## ASV0016     -4.762843e-03 -4.965350e-03 -5.175492e-03 -5.393481e-03
## ASV5394     -3.631791e-03 -3.790822e-03 -3.956234e-03 -4.128236e-03
## ASV0666      7.503615e-03  7.801426e-03  8.108745e-03  8.425704e-03
## ASV2085      1.295785e-03  1.313540e-03  1.328883e-03  1.341503e-03
## ASV0003     -3.244066e-03 -3.381735e-03 -3.524574e-03 -3.672726e-03
## ASV0346      1.730866e-03  1.811592e-03  1.895912e-03  1.983963e-03
## ASV0267      8.758577e-05  9.894176e-05  1.113482e-04  1.248799e-04
## ASV0353      2.708671e-03  2.832528e-03  2.961802e-03  3.096707e-03
## ASV2419      6.914597e-03  7.203015e-03  7.501870e-03  7.811423e-03
## ASV0447      3.983846e-03  4.166651e-03  4.357461e-03  4.556588e-03
## ASV0654      5.650956e-03  5.891920e-03  6.141996e-03  6.401436e-03
## ASV0151      8.780009e-04  9.251176e-04  9.748662e-04  1.027393e-03
## ASV0065     -2.160107e-03 -2.250265e-03 -2.343683e-03 -2.440440e-03
## ASV0527      5.349214e-03  5.575479e-03  5.810194e-03  6.053590e-03
## ASV4055     -9.445474e-04 -9.926892e-04 -1.043428e-03 -1.096915e-03
## ASV0166     -2.596334e-03 -2.699226e-03 -2.805379e-03 -2.914836e-03
## ASV0417     -1.003225e-03 -1.038326e-03 -1.074123e-03 -1.110585e-03
## ASV0078     -1.550800e-03 -1.613003e-03 -1.677208e-03 -1.743439e-03
## ASV0322     -1.848769e-04 -1.835083e-04 -1.811505e-04 -1.776784e-04
## ASV0156     -3.899474e-03 -4.073271e-03 -4.254364e-03 -4.443024e-03
## ASV0648     -8.513907e-03 -8.896248e-03 -9.294781e-03 -9.710110e-03
## ASV0407     -6.610897e-04 -6.925935e-04 -7.255980e-04 -7.601746e-04
## ASV2030     -1.363520e-03 -1.422144e-03 -1.483255e-03 -1.546973e-03
## ASV0300      1.045870e-03  1.094944e-03  1.146249e-03  1.199877e-03
## ASV1150      2.618621e-04  2.759947e-04  2.908975e-04  3.066092e-04
## ASV0958      3.249019e-03  3.403390e-03  3.565036e-03  3.734292e-03
## ASV0216     -3.319718e-03 -3.458133e-03 -3.601696e-03 -3.750568e-03
## ASV0446      5.243722e-03  5.478588e-03  5.723292e-03  5.978184e-03
## ASV0367     -3.388281e-03 -3.536778e-03 -3.691270e-03 -3.851961e-03
## ASV0200     -2.010376e-03 -2.097988e-03 -2.189079e-03 -2.283758e-03
## ASV0334     -9.120074e-04 -9.389857e-04 -9.660931e-04 -9.932755e-04
## ASV1311      1.162420e-03  1.201122e-03  1.240364e-03  1.280084e-03
## ASV0458      1.694595e-03  1.749676e-03  1.805478e-03  1.861917e-03
## ASV1371      3.480411e-04  3.653329e-04  3.834505e-04  4.024258e-04
## ASV0418      4.228554e-03  4.394542e-03  4.565703e-03  4.742104e-03
## ASV0004      6.080668e-04  6.315314e-04  6.556897e-04  6.805468e-04
## ASV1943      1.067433e-02  1.101685e-02  1.136423e-02  1.171611e-02
## ASV1495     -1.179804e-03 -1.252826e-03 -1.330592e-03 -1.413407e-03
## ASV0901     -3.900170e-03 -4.078616e-03 -4.264953e-03 -4.459511e-03
## ASV0628      1.835550e-03  1.901781e-03  1.969499e-03  2.038657e-03
## ASV0400      1.166956e-03  1.213059e-03  1.260566e-03  1.309484e-03
## ASV0116     -1.142917e-03 -1.194866e-03 -1.249076e-03 -1.305639e-03
## ASV0788      1.013656e-02  1.059985e-02  1.108352e-02  1.158840e-02
## ASV0117      7.746546e-04  8.120113e-04  8.511514e-04  8.921556e-04
## ASV3137     -2.204760e-04 -2.292896e-04 -2.383854e-04 -2.477662e-04
## ASV0001      6.476250e-04  6.721708e-04  6.973975e-04  7.233052e-04
## ASV1651      1.870441e-03  1.943415e-03  2.018618e-03  2.096074e-03
## ASV1692      8.417225e-03  8.799734e-03  9.198839e-03  9.615193e-03
## ASV0660      2.623273e-03  2.713982e-03  2.806284e-03  2.900065e-03
## ASV0508      1.276443e-04  1.318118e-04  1.360381e-04  1.403172e-04
## ASV1660     -1.815175e-03 -1.905839e-03 -2.001001e-03 -2.100865e-03
## ASV0233      2.536049e-03  2.646578e-03  2.761520e-03  2.881020e-03
## ASV1343     -4.775866e-03 -4.991727e-03 -5.216882e-03 -5.451698e-03
## ASV0209      2.172050e-03  2.254841e-03  2.339966e-03  2.427430e-03
## ASV0193     -2.558720e-03 -2.657858e-03 -2.759904e-03 -2.864868e-03
## ASV0357      1.203330e-03  1.268251e-03  1.336879e-03  1.409434e-03
## ASV0198      2.007515e-03  2.090715e-03  2.176907e-03  2.266170e-03
## ASV0007      5.600480e-04  5.803449e-04  6.011193e-04  6.223623e-04
## ASV1772     -7.923952e-04 -8.166513e-04 -8.408582e-04 -8.649105e-04
## ASV0009      4.522723e-04  4.678199e-04  4.836530e-04  4.997564e-04
## ASV0006     -5.893650e-04 -6.175370e-04 -6.470376e-04 -6.779260e-04
## ASV0011     -1.956928e-03 -2.044331e-03 -2.135397e-03 -2.230260e-03
## ASV0015      3.410982e-04  3.527365e-04  3.645757e-04  3.766024e-04
## ASV0017      3.855454e-04  3.988481e-04  4.124021e-04  4.261953e-04
## ASV0235     -1.820893e-03 -1.903072e-03 -1.988752e-03 -2.078067e-03
## ASV0382      1.417783e-03  1.480574e-03  1.545840e-03  1.613643e-03
## ASV2357      5.888258e-03  6.151026e-03  6.424838e-03  6.710106e-03
## ASV0567     -1.158327e-03 -1.211712e-03 -1.267537e-03 -1.325914e-03
## ASV0165      9.805431e-04  1.024019e-03  1.069276e-03  1.116374e-03
## ASV0005      1.385144e-03  1.443796e-03  1.504628e-03  1.567697e-03
## ASV0384     -6.181359e-05 -5.749937e-05 -5.240588e-05 -4.645640e-05
## ASV0002      2.500179e-04  2.600002e-04  2.703161e-04  2.809729e-04
## ASV3017      7.021893e-03  7.295883e-03  7.578161e-03  7.868794e-03
## ASV0091     -1.838751e-04 -1.916854e-04 -1.998172e-04 -2.082859e-04
## ASV0186     -2.811620e-03 -2.932092e-03 -3.057149e-03 -3.186916e-03
## ASV0370      1.456627e-03  1.516496e-03  1.578445e-03  1.642520e-03
## ASV0018      1.781842e-03  1.857872e-03  1.936781e-03  2.018649e-03
## ASV1377      1.722333e-02  1.791100e-02  1.862092e-02  1.935343e-02
## ASV0019      1.871701e-03  1.951759e-03  2.034867e-03  2.121111e-03
## ASV0023     -1.211065e-03 -1.265976e-03 -1.323242e-03 -1.382951e-03
## ASV2194      1.979481e-03  2.072065e-03  2.168914e-03  2.270218e-03
## ASV1155      7.211788e-03  7.502688e-03  7.803592e-03  8.114739e-03
## ASV0510     -1.807865e-03 -1.870593e-03 -1.934567e-03 -1.999745e-03
## ASV2371     -4.340001e-03 -4.514327e-03 -4.694513e-03 -4.880678e-03
## ASV0024     -1.502279e-03 -1.569985e-03 -1.640565e-03 -1.714123e-03
## ASV2452      4.171294e-03  4.322855e-03  4.477949e-03  4.636495e-03
## ASV2332     -1.260812e-02 -1.312590e-02 -1.366211e-02 -1.421723e-02
## ASV2591      3.824964e-03  4.018710e-03  4.221973e-03  4.435151e-03
## ASV0521      3.049368e-03  3.186801e-03  3.330101e-03  3.479491e-03
## ASV5542      2.911665e-03  3.041489e-03  3.176639e-03  3.317293e-03
## ASV0336     -4.648621e-04 -4.927216e-04 -5.222889e-04 -5.536626e-04
## ASV10102     5.378293e-03  5.618864e-03  5.869450e-03  6.130400e-03
## ASV16823    -7.564923e-03 -7.852562e-03 -8.148597e-03 -8.453106e-03
## ASV3104      3.912693e-02  4.061405e-02  4.214454e-02  4.371881e-02
## ASV0781      5.822800e-03  6.070996e-03  6.328652e-03  6.596050e-03
## ASV10899     3.924150e-03  4.129286e-03  4.345356e-03  4.572929e-03
## ASV11222    -1.330787e-02 -1.381365e-02 -1.433419e-02 -1.486963e-02
## ASV11327    -1.194335e-02 -1.239709e-02 -1.286406e-02 -1.334438e-02
## ASV12458    -1.329725e-02 -1.380224e-02 -1.432192e-02 -1.485645e-02
## ASV1636      7.793468e-03  8.109113e-03  8.435409e-03  8.772563e-03
## ASV1890     -5.848578e-03 -6.051086e-03 -6.257953e-03 -6.469098e-03
## ASV2898      1.046687e-02  1.089229e-02  1.133220e-02  1.178688e-02
## ASV8328      2.056664e-03  2.203320e-03  2.360362e-03  2.528470e-03
## ASV0709     -1.185645e-02 -1.235160e-02 -1.286457e-02 -1.339579e-02
## ASV0856      1.045900e-02  1.094320e-02  1.144890e-02  1.197699e-02
## ASV0909      3.509978e-03  3.708344e-03  3.918297e-03  4.140492e-03
## ASV0937     -7.259135e-03 -7.587061e-03 -7.929272e-03 -8.286363e-03
## ASV11390    -1.897299e-02 -1.969342e-02 -2.043483e-02 -2.119741e-02
## ASV11966     5.247413e-03  5.498697e-03  5.761682e-03  6.036861e-03
## ASV12990     3.397564e-03  3.531712e-03  3.670035e-03  3.812581e-03
## ASV14797     4.979416e-03  5.172840e-03  5.372118e-03  5.577314e-03
## ASV14904    -2.722403e-02 -2.825777e-02 -2.932162e-02 -3.041585e-02
## ASV15304     3.427694e-03  3.601251e-03  3.783516e-03  3.974888e-03
## ASV16696    -9.404006e-03 -9.761029e-03 -1.012845e-02 -1.050636e-02
## ASV1690      1.779012e-02  1.861115e-02  1.946789e-02  2.036165e-02
## ASV2029      1.161834e-02  1.210241e-02  1.260405e-02  1.312373e-02
## ASV2834      1.504643e-02  1.570966e-02  1.639980e-02  1.711775e-02
## ASV4003      1.312333e-02  1.376156e-02  1.443099e-02  1.513312e-02
## ASV4064      7.198323e-03  7.519628e-03  7.854255e-03  8.202667e-03
## ASV4294      4.757613e-03  5.001079e-03  5.257198e-03  5.526614e-03
## ASV4609      3.904709e-03  4.065324e-03  4.231623e-03  4.403755e-03
## ASV6283     -8.793954e-03 -9.128054e-03 -9.471911e-03 -9.825620e-03
## ASV6491     -1.259944e-02 -1.307793e-02 -1.357038e-02 -1.407693e-02
## ASV7453      7.003594e-03  7.342117e-03  7.696631e-03  8.067824e-03
## ASV7959      2.800068e-03  2.955459e-03  3.119660e-03  3.293147e-03
## ASV8219      1.088732e-01  1.130081e-01  1.172637e-01  1.216412e-01
## ASV8547     -1.127449e-02 -1.170251e-02 -1.214302e-02 -1.259613e-02
## ASV9319      5.465751e-03  5.717644e-03  5.980711e-03  6.255410e-03
## ASV9382     -2.205582e-02 -2.289306e-02 -2.375471e-02 -2.464102e-02
## ASV11516    -1.472565e-02 -1.528442e-02 -1.585946e-02 -1.645095e-02
## ASV14377    -1.062848e-02 -1.103162e-02 -1.144649e-02 -1.187322e-02
## ASV1867      9.012212e-03  9.415741e-03  9.836222e-03  1.027427e-02
## ASV1895      4.072001e-03  4.218366e-03  4.367856e-03  4.520348e-03
## ASV3168      5.269071e-03  5.471413e-03  5.679498e-03  5.893332e-03
## ASV4449      3.052445e-02  3.183093e-02  3.318834e-02  3.459833e-02
## ASV6596      6.970424e-03  7.316576e-03  7.680093e-03  8.061832e-03
## ASV7492     -5.967762e-04 -5.801742e-04 -5.596786e-04 -5.349406e-04
## ASV9854     -2.238275e-03 -2.321051e-03 -2.406136e-03 -2.493549e-03
## ASV6296      1.782737e-01  1.850334e-01  1.919897e-01  1.991447e-01
## ASV4201      1.521008e-03  1.632526e-03  1.752106e-03  1.880283e-03
## ASV0552      6.203952e-03  6.479132e-03  6.765632e-03  7.063839e-03
## ASV3671     -4.003591e-03 -4.173658e-03 -4.350500e-03 -4.534384e-03
## ASV3529     -6.149910e-04 -6.096374e-04 -6.018306e-04 -5.913630e-04
## ASV1060      1.712838e-03  1.794173e-03  1.879379e-03  1.968642e-03
## ASV0239     -2.014529e-03 -2.087710e-03 -2.162678e-03 -2.239414e-03
## ASV5711     -9.664496e-03 -1.006199e-02 -1.047372e-02 -1.090006e-02
## ASV4152     -1.410800e-02 -1.472116e-02 -1.535876e-02 -1.602161e-02
## ASV1461      6.553936e-03  6.795760e-03  7.043743e-03  7.297837e-03
## ASV2877      3.447182e-03  3.577553e-03  3.711478e-03  3.848948e-03
## ASV0012      6.344885e-04  6.618306e-04  6.902447e-04  7.197655e-04
## ASV9823      6.986214e-04  7.121513e-04  7.247264e-04  7.361867e-04
## ASV0008      6.719102e-04  7.005085e-04  7.302027e-04  7.610267e-04
## ASV7832     -8.371675e-03 -8.741846e-03 -9.127449e-03 -9.529060e-03
## ASV1915     -1.008967e-03 -1.050478e-03 -1.093616e-03 -1.138452e-03
## ASV0055     -8.171434e-04 -8.590979e-04 -9.032505e-04 -9.497144e-04
## ASV0032      2.842929e-04  2.924701e-04  3.006466e-04  3.087999e-04
## ASV2977     -1.165232e-02 -1.215450e-02 -1.267631e-02 -1.321839e-02
## ASV0466      8.685976e-03  9.007730e-03  9.337780e-03  9.676064e-03
## ASV3866      6.603643e-03  6.903934e-03  7.217296e-03  7.544251e-03
## ASV0040      2.338886e-03  2.441632e-03  2.548548e-03  2.659777e-03
## ASV0496     -8.318746e-04 -8.895359e-04 -9.512257e-04 -1.017204e-03
## ASV0052      1.966424e-03  2.052986e-03  2.143072e-03  2.236803e-03
## ASV3828     -6.292290e-03 -6.529104e-03 -6.772654e-03 -7.022990e-03
## ASV1930      3.321924e-03  3.452850e-03  3.587769e-03  3.726708e-03
## ASV2126      5.809818e-03  6.052214e-03  6.303445e-03  6.563743e-03
## ASV0793      7.437978e-03  7.772433e-03  8.121054e-03  8.484364e-03
## ASV0299     -1.641287e-04 -1.736814e-04 -1.839412e-04 -1.949740e-04
## ASV0208      5.295489e-03  5.528323e-03  5.770671e-03  6.022870e-03
## ASV0511     -1.965465e-03 -2.035407e-03 -2.106889e-03 -2.179873e-03
## ASV1123     -6.032098e-03 -6.255105e-03 -6.483954e-03 -6.718626e-03
## ASV0099      2.343409e-04  2.477129e-04  2.619208e-04  2.770206e-04
## ASV0752     -3.923922e-03 -4.107877e-03 -4.300210e-03 -4.501275e-03
## ASV0883      5.353756e-03  5.602395e-03  5.862128e-03  6.133398e-03
## ASV0683      6.923207e-03  7.239598e-03  7.569798e-03  7.914349e-03
## ASV4117     -1.077275e-02 -1.124771e-02 -1.174231e-02 -1.225730e-02
## ASV2172      5.676112e-04  5.821609e-04  5.964231e-04  6.103179e-04
## ASV0330     -2.032048e-03 -2.122909e-03 -2.217605e-03 -2.316282e-03
## ASV0728      9.793955e-03  1.021172e-02  1.064532e-02  1.109519e-02
## ASV0499      2.708171e-03  2.833158e-03  2.963718e-03  3.100081e-03
## ASV0120     -4.355028e-03 -4.541563e-03 -4.735202e-03 -4.936143e-03
## ASV1446      2.853363e-03  2.938560e-03  3.024065e-03  3.109659e-03
## ASV17171    -8.408622e-03 -8.771281e-03 -9.148385e-03 -9.540440e-03
## ASV0533      6.856334e-04  7.196813e-04  7.554255e-04  7.929470e-04
## ASV2495     -2.356997e-03 -2.482462e-03 -2.614931e-03 -2.754795e-03
## ASV5582      3.447888e-03  3.561999e-03  3.677814e-03  3.795187e-03
## ASV1488      1.416728e-03  1.471705e-03  1.528250e-03  1.586356e-03
## ASV0682      1.985150e-03  2.077559e-03  2.174131e-03  2.275038e-03
## ASV0068     -3.317137e-03 -3.460695e-03 -3.609838e-03 -3.764728e-03
## ASV1987     -8.685116e-03 -9.094730e-03 -9.523169e-03 -9.971233e-03
## ASV0035     -7.987579e-04 -8.486100e-04 -9.017970e-04 -9.585475e-04
## ASV7192     -4.982719e-03 -5.187319e-03 -5.399109e-03 -5.618254e-03
## ASV0873     -3.673985e-03 -4.059311e-03 -4.476353e-03 -4.927172e-03
## ASV4749     -7.292872e-04 -8.048437e-04 -8.870020e-04 -9.762527e-04
## ASV2174      3.195875e-03  3.305237e-03  3.416523e-03  3.529612e-03
## ASV1476     -3.818102e-03 -3.996896e-03 -4.183965e-03 -4.379683e-03
## ASV0740     -1.078571e-02 -1.128463e-02 -1.180592e-02 -1.235051e-02
## ASV0170     -2.040505e-03 -2.129528e-03 -2.222120e-03 -2.318399e-03
## ASV2466     -9.321191e-03 -9.730287e-03 -1.015612e-02 -1.059928e-02
## ASV1709      3.273394e-03  3.408063e-03  3.547861e-03  3.692987e-03
## ASV6170     -1.487697e-02 -1.555043e-02 -1.625290e-02 -1.698552e-02
## ASV3673      7.395655e-03  7.737267e-03  8.094123e-03  8.466853e-03
## ASV1745     -2.001051e-03 -2.099975e-03 -2.203819e-03 -2.312820e-03
##                                                                    
## (Intercept)  5.859132e-02  6.108619e-02  6.367468e-02  6.635932e-02
## ASV1236      1.099246e-02  1.142405e-02  1.186934e-02  1.232855e-02
## ASV0421      1.677802e-03  1.773356e-03  1.874379e-03  1.981151e-03
## ASV0691     -7.736756e-03 -7.984841e-03 -8.236485e-03 -8.491437e-03
## ASV0899      9.556920e-03  9.931270e-03  1.031705e-02  1.071435e-02
## ASV1004      2.207976e-02  2.294874e-02  2.384512e-02  2.476930e-02
## ASV1041     -8.971708e-03 -9.314084e-03 -9.665931e-03 -1.002722e-02
## ASV1058      1.375775e-02  1.429855e-02  1.485649e-02  1.543184e-02
## ASV12542     5.174260e-03  5.366982e-03  5.565019e-03  5.768403e-03
## ASV1294      1.283062e-02  1.333686e-02  1.385930e-02  1.439823e-02
## ASV13113     4.845719e-03  5.077534e-03  5.320352e-03  5.574679e-03
## ASV1318      1.277061e-02  1.327219e-02  1.378954e-02  1.432288e-02
## ASV2269     -2.197915e-02 -2.283041e-02 -2.370705e-02 -2.460928e-02
## ASV2542      1.163080e-02  1.214976e-02  1.269054e-02  1.325396e-02
## ASV2660     -8.685278e-03 -9.018045e-03 -9.360532e-03 -9.712809e-03
## ASV2737      2.850194e-03  2.949674e-03  3.051429e-03  3.155447e-03
## ASV2840      1.118196e-02  1.158154e-02  1.199026e-02  1.240796e-02
## ASV3053      5.843090e-02  6.061995e-02  6.287017e-02  6.518195e-02
## ASV3077      3.753273e-03  3.896162e-03  4.043292e-03  4.194720e-03
## ASV3134      7.575714e-03  7.927816e-03  8.295883e-03  8.680601e-03
## ASV3140      9.725808e-03  1.014013e-02  1.057012e-02  1.101623e-02
## ASV3579      3.855558e-03  4.048324e-03  4.250757e-03  4.463318e-03
## ASV6119     -6.012950e-03 -6.245768e-03 -6.485529e-03 -6.732288e-03
## ASV7557     -1.221354e-02 -1.268620e-02 -1.317292e-02 -1.367383e-02
## ASV8422      2.993846e-03  3.107201e-03  3.223876e-03  3.343910e-03
## ASV1086     -4.151390e-04 -4.276829e-04 -4.404025e-04 -4.532946e-04
## ASV1310      5.875382e-03  6.104740e-03  6.341160e-03  6.584725e-03
## ASV15750    -7.287114e-04 -7.519241e-04 -7.753743e-04 -7.990190e-04
## ASV16905    -2.511521e-03 -2.608719e-03 -2.708812e-03 -2.811823e-03
## ASV2033      1.181767e-02  1.235212e-02  1.290928e-02  1.348998e-02
## ASV2089      5.303363e-03  5.509075e-03  5.720947e-03  5.939031e-03
## ASV2127      1.728513e-02  1.796211e-02  1.866026e-02  1.937989e-02
## ASV2725      1.353843e-02  1.404879e-02  1.457348e-02  1.511257e-02
## ASV2804     -5.198292e-03 -5.399466e-03 -5.606638e-03 -5.819854e-03
## ASV3075      1.197251e-02  1.248114e-02  1.300956e-02  1.355843e-02
## ASV3327      1.705417e-02  1.780622e-02  1.858887e-02  1.940317e-02
## ASV3342      1.453486e-02  1.516879e-02  1.582814e-02  1.651374e-02
## ASV3532     -1.579689e-02 -1.647119e-02 -1.717155e-02 -1.789881e-02
## ASV3600      7.388036e-03  7.706131e-03  8.036677e-03  8.380071e-03
## ASV4013      1.334466e-02  1.388894e-02  1.445197e-02  1.503414e-02
## ASV4136      1.367139e-02  1.419422e-02  1.473261e-02  1.528676e-02
## ASV4195      5.303846e-02  5.509015e-02  5.720293e-02  5.937731e-02
## ASV4407     -2.048284e-02 -2.127476e-02 -2.209022e-02 -2.292943e-02
## ASV4717      3.296366e-03  3.407234e-03  3.520270e-03  3.635427e-03
## ASV6794      8.226496e-03  8.530236e-03  8.842303e-03  9.162761e-03
## ASV8324     -1.051013e-02 -1.091646e-02 -1.133487e-02 -1.176545e-02
## ASV8981     -5.802543e-05 -4.575803e-05 -3.180734e-05 -1.602918e-05
## ASV9859      4.452653e-03  4.683863e-03  4.927499e-03  5.184234e-03
## ASV0936      1.095327e-02  1.142863e-02  1.192256e-02  1.243561e-02
## ASV12683    -6.893606e-05 -7.492687e-05 -8.129017e-05 -8.803444e-05
## ASV1293      6.806810e-03  7.069859e-03  7.340812e-03  7.619750e-03
## ASV13055    -1.293393e-05 -2.873178e-06  8.437310e-06  2.110007e-05
## ASV17063    -5.444858e-03 -5.655046e-03 -5.871467e-03 -6.094170e-03
## ASV2228      4.438322e-03  4.609565e-03  4.785878e-03  4.967300e-03
## ASV2769      9.151208e-04  9.650782e-04  1.017731e-03  1.073205e-03
## ASV2803      4.588870e-03  4.752479e-03  4.919966e-03  5.091297e-03
## ASV2896      4.209614e-03  4.399574e-03  4.597835e-03  4.804750e-03
## ASV3062      5.389235e-03  5.650109e-03  5.923413e-03  6.209692e-03
## ASV3107      7.726560e-03  8.065804e-03  8.418923e-03  8.786415e-03
## ASV3265      9.698849e-03  1.007069e-02  1.045344e-02  1.084718e-02
## ASV3666      6.626315e-05  6.655957e-05  6.662998e-05  6.644630e-05
## ASV4497      3.397898e-03  3.532839e-03  3.672153e-03  3.815914e-03
## ASV6914     -6.412748e-04 -6.757474e-04 -7.120801e-04 -7.503644e-04
## ASV0576     -1.097169e-02 -1.135360e-02 -1.174374e-02 -1.214195e-02
## ASV0673      1.322813e-02  1.376234e-02  1.431451e-02  1.488502e-02
## ASV0772      6.223982e-03  6.481886e-03  6.749128e-03  7.025962e-03
## ASV0862      1.146685e-03  1.229489e-03  1.317969e-03  1.412450e-03
## ASV0898      5.183980e-03  5.420650e-03  5.667460e-03  5.924771e-03
## ASV0910      5.833757e-03  6.092228e-03  6.361395e-03  6.641641e-03
## ASV0964     -4.220585e-03 -4.371911e-03 -4.526814e-03 -4.685250e-03
## ASV10059     4.346837e-03  4.551968e-03  4.766544e-03  4.990967e-03
## ASV10263    -8.312396e-03 -8.634494e-03 -8.966262e-03 -9.307786e-03
## ASV1088      1.028967e-02  1.074045e-02  1.120978e-02  1.169833e-02
## ASV1101      1.183154e-02  1.228671e-02  1.275532e-02  1.323746e-02
## ASV1183      3.318195e-03  3.459306e-03  3.605801e-03  3.757844e-03
## ASV11956     2.848990e-03  2.947543e-03  3.048226e-03  3.151011e-03
## ASV12774     5.226443e-06 -6.270518e-06 -1.911280e-05 -3.340247e-05
## ASV1321      1.522970e-02  1.591477e-02  1.662888e-02  1.737313e-02
## ASV13793    -5.729853e-03 -5.951779e-03 -6.180355e-03 -6.415642e-03
## ASV14482     3.165929e-04  3.264945e-04  3.366122e-04  3.469548e-04
## ASV15483     2.543757e-03  2.655161e-03  2.771021e-03  2.891479e-03
## ASV2062      1.129523e-02  1.175573e-02  1.223225e-02  1.272518e-02
## ASV2132      9.641602e-03  1.006188e-02  1.049890e-02  1.095318e-02
## ASV2413      8.561991e-03  8.899965e-03  9.248844e-03  9.608825e-03
## ASV2490      2.546423e-02  2.640893e-02  2.737907e-02  2.837471e-02
## ASV2594      3.482691e-03  3.634160e-03  3.791855e-03  3.956020e-03
## ASV2822     -1.513639e-02 -1.572370e-02 -1.632872e-02 -1.695162e-02
## ASV2863      1.591852e-02  1.652736e-02  1.715432e-02  1.779959e-02
## ASV2910      5.881544e-03  6.109643e-03  6.344705e-03  6.586819e-03
## ASV2980      6.776080e-03  7.053130e-03  7.339805e-03  7.636322e-03
## ASV3307      1.203346e-02  1.249983e-02  1.298022e-02  1.347475e-02
## ASV3474      8.840472e-03  9.245469e-03  9.668166e-03  1.010925e-02
## ASV3502      8.771705e-03  9.141742e-03  9.525657e-03  9.923853e-03
## ASV4236      1.184170e-02  1.227059e-02  1.270997e-02  1.315974e-02
## ASV4842     -1.432287e-03 -1.493103e-03 -1.555915e-03 -1.620721e-03
## ASV4894     -5.736176e-03 -5.958750e-03 -6.188042e-03 -6.424117e-03
## ASV5290      4.863679e-03  5.073520e-03  5.291508e-03  5.517888e-03
## ASV5501      2.943379e-03  3.070294e-03  3.202393e-03  3.339883e-03
## ASV5795      3.285153e-03  3.428152e-03  3.576823e-03  3.731344e-03
## ASV5987     -1.602958e-02 -1.665209e-02 -1.729345e-02 -1.795385e-02
## ASV6267     -1.805406e-02 -1.875482e-02 -1.947676e-02 -2.022011e-02
## ASV6862      7.072216e-03  7.336650e-03  7.608475e-03  7.887741e-03
## ASV7145      3.066990e-03  3.179627e-03  3.295468e-03  3.414567e-03
## ASV7673     -5.735801e-03 -5.958399e-03 -6.187725e-03 -6.423845e-03
## ASV7789      3.415923e-03  3.589308e-03  3.771615e-03  3.963290e-03
## ASV7809      4.032689e-04  4.332391e-04  4.653190e-04  4.996342e-04
## ASV8002     -7.244798e-03 -7.526085e-03 -7.815894e-03 -8.114312e-03
## ASV8205      3.226686e-03  3.365843e-03  3.510482e-03  3.660783e-03
## ASV9155     -1.781847e-03 -1.846806e-03 -1.913363e-03 -1.981501e-03
## ASV9221      1.125708e-03  1.196410e-03  1.271654e-03  1.351714e-03
## ASV9311     -1.162085e-02 -1.207211e-02 -1.253705e-02 -1.301584e-02
## ASV9557     -7.938431e-03 -8.246531e-03 -8.563963e-03 -8.890827e-03
## ASV9936     -1.600179e-02 -1.662250e-02 -1.726199e-02 -1.792046e-02
## ASV1445      1.034273e-02  1.078737e-02  1.124924e-02  1.172889e-02
## ASV4232      4.195081e-03  4.396030e-03  4.606688e-03  4.827530e-03
## ASV6479      1.848697e-03  1.958553e-03  2.075138e-03  2.198851e-03
## ASV0142     -6.838955e-03 -7.100917e-03 -7.370628e-03 -7.648164e-03
## ASV0378      3.554262e-03  3.721553e-03  3.896446e-03  4.079249e-03
## ASV1122      1.011139e-02  1.055299e-02  1.101230e-02  1.148991e-02
## ASV0123     -6.021843e-03 -6.251269e-03 -6.487372e-03 -6.730207e-03
## ASV2064      2.874373e-03  2.968529e-03  3.063970e-03  3.160556e-03
## ASV4459     -3.552135e-04 -3.641932e-04 -3.731610e-04 -3.821105e-04
## ASV0448      2.846789e-03  2.981091e-03  3.121536e-03  3.268377e-03
## ASV0397      5.757176e-03  5.996115e-03  6.243632e-03  6.499938e-03
## ASV0485      6.572186e-03  6.837582e-03  7.111998e-03  7.395627e-03
## ASV1566      9.815613e-03  1.022016e-02  1.063901e-02  1.107249e-02
## ASV1365      8.515758e-03  8.874706e-03  9.246830e-03  9.632453e-03
## ASV1065      1.208273e-02  1.259251e-02  1.312131e-02  1.366966e-02
## ASV0722     -6.733702e-04 -7.051983e-04 -7.385673e-04 -7.735573e-04
## ASV12660    -6.497363e-03 -6.743581e-03 -6.996917e-03 -7.257429e-03
## ASV0223      1.830092e-03  1.905219e-03  1.983032e-03  2.063604e-03
## ASV0229      2.925717e-03  3.054699e-03  3.188986e-03  3.328770e-03
## ASV0877      1.008342e-03  1.036487e-03  1.064262e-03  1.091512e-03
## ASV0983      6.460576e-03  6.716514e-03  6.980660e-03  7.253140e-03
## ASV0626      1.062084e-03  1.128622e-03  1.199239e-03  1.274151e-03
## ASV4146      2.876369e-04  2.949979e-04  3.019681e-04  3.084468e-04
## ASV4175     -8.413557e-03 -8.778212e-03 -9.157220e-03 -9.551033e-03
## ASV2082     -4.512613e-03 -4.758542e-03 -5.018406e-03 -5.292986e-03
## ASV2272      3.988595e-03  4.161209e-03  4.340720e-03  4.527367e-03
## ASV2245     -6.054380e-03 -6.319623e-03 -6.595508e-03 -6.882382e-03
## ASV0590     -4.440396e-03 -4.691505e-03 -4.957249e-03 -5.238454e-03
## ASV0217      8.049031e-04  8.716430e-04  9.434023e-04  1.020497e-03
## ASV0416      3.879065e-03  4.002377e-03  4.127101e-03  4.253041e-03
## ASV1056      5.977347e-03  6.247046e-03  6.528131e-03  6.821005e-03
## ASV7777     -8.137619e-03 -8.488295e-03 -8.852824e-03 -9.231677e-03
## ASV0455      1.438158e-03  1.498226e-03  1.560454e-03  1.624890e-03
## ASV0604      4.004409e-03  4.189506e-03  4.382749e-03  4.584451e-03
## ASV6100     -5.715204e-03 -5.968885e-03 -6.233193e-03 -6.508533e-03
## ASV11359    -1.202764e-02 -1.254165e-02 -1.307524e-02 -1.362897e-02
## ASV6604      1.749864e-03  1.830121e-03  1.913871e-03  2.001246e-03
## ASV5004     -4.239644e-03 -4.419092e-03 -4.605364e-03 -4.798669e-03
## ASV1483     -1.804106e-03 -1.878723e-03 -1.956003e-03 -2.036011e-03
## ASV9773     -5.473418e-03 -5.711962e-03 -5.960100e-03 -6.218165e-03
## ASV4059      3.939526e-04  4.361427e-04  4.819307e-04  5.315629e-04
## ASV1193      6.437186e-03  6.705522e-03  6.983628e-03  7.271760e-03
## ASV4610     -5.227549e-04 -5.138507e-04 -5.024547e-04 -4.883738e-04
## ASV0742     -1.858126e-04 -1.659385e-04 -1.432636e-04 -1.175781e-04
## ASV1502     -5.661038e-04 -6.079868e-04 -6.528171e-04 -7.007713e-04
## ASV0195     -6.225359e-06 -1.693145e-05 -2.881540e-05 -4.196202e-05
## ASV1213      4.119221e-03  4.263531e-03  4.410960e-03  4.561439e-03
## ASV1648     -5.122952e-03 -5.350037e-03 -5.586662e-03 -5.833200e-03
## ASV6984     -4.803697e-03 -5.017528e-03 -5.240437e-03 -5.472787e-03
## ASV0396     -8.789689e-05 -8.099407e-05 -7.315419e-05 -6.432460e-05
## ASV4297      6.141299e-03  6.368061e-03  6.600755e-03  6.839366e-03
## ASV2622      9.844287e-03  1.023090e-02  1.062974e-02  1.104100e-02
## ASV3512      4.589117e-03  4.823653e-03  5.070480e-03  5.330242e-03
## ASV2411      7.386016e-03  7.723254e-03  8.075170e-03  8.442333e-03
## ASV2291     -3.917057e-03 -4.141859e-03 -4.379828e-03 -4.631689e-03
## ASV0807      9.479776e-03  9.873889e-03  1.028210e-02  1.070475e-02
## ASV1292      2.001148e-03  2.065826e-03  2.131430e-03  2.197885e-03
## ASV1035      8.289000e-03  8.609499e-03  8.939910e-03  9.280389e-03
## ASV0070      2.640689e-04  2.880349e-04  3.139551e-04  3.419669e-04
## ASV0255      7.148106e-04  7.365993e-04  7.584287e-04  7.802269e-04
## ASV0057     -2.171490e-03 -2.247180e-03 -2.324423e-03 -2.403168e-03
## ASV0077     -3.915265e-04 -4.001864e-04 -4.085654e-04 -4.166154e-04
## ASV0625      4.696105e-03  4.871336e-03  5.051324e-03  5.236076e-03
## ASV2464      3.184937e-02  3.303839e-02  3.426060e-02  3.551621e-02
## ASV1315      9.694026e-03  1.014104e-02  1.060782e-02  1.109516e-02
## ASV2673      8.335700e-03  8.721503e-03  9.124498e-03  9.545382e-03
## ASV2161      3.514056e-03  3.676504e-03  3.846246e-03  4.023593e-03
## ASV0337     -1.937731e-03 -2.022272e-03 -2.110194e-03 -2.201608e-03
## ASV7680     -1.271817e-02 -1.327832e-02 -1.386134e-02 -1.446802e-02
## ASV0611      7.127787e-03  7.443842e-03  7.773036e-03  8.115851e-03
## ASV3118     -7.693980e-03 -8.053087e-03 -8.428368e-03 -8.820483e-03
## ASV1284      1.316337e-03  1.288490e-03  1.252745e-03  1.208340e-03
## ASV0889      5.059735e-03  5.263313e-03  5.473836e-03  5.691467e-03
## ASV4649     -2.634020e-03 -2.746430e-03 -2.863172e-03 -2.984381e-03
## ASV1108     -5.888026e-03 -6.171820e-03 -6.469155e-03 -6.780643e-03
## ASV0738      3.535453e-03  3.723233e-03  3.921252e-03  4.130056e-03
## ASV0473     -8.107731e-04 -8.575529e-04 -9.069244e-04 -9.590015e-04
## ASV0598     -1.915868e-03 -2.024278e-03 -2.139095e-03 -2.260695e-03
## ASV0429      3.640130e-03  3.777443e-03  3.918505e-03  4.063309e-03
## ASV1549      7.709814e-03  8.067833e-03  8.441893e-03  8.832646e-03
## ASV1203      5.521979e-03  5.744169e-03  5.973762e-03  6.210894e-03
## ASV4532      1.647625e-04  1.673235e-04  1.697410e-04  1.720078e-04
## ASV0274      1.117555e-03  1.172330e-03  1.229655e-03  1.289624e-03
## ASV0163     -4.064223e-03 -4.215628e-03 -4.371247e-03 -4.531114e-03
## ASV1298      3.831947e-04  3.946300e-04  4.063411e-04  4.183560e-04
## ASV9424     -9.953456e-03 -1.039914e-02 -1.086377e-02 -1.134806e-02
## ASV0412      9.495709e-03  9.873131e-03  1.026285e-02  1.066509e-02
## ASV0284      1.697332e-03  1.745192e-03  1.792924e-03  1.840374e-03
## ASV0620     -2.413644e-03 -2.540967e-03 -2.675088e-03 -2.816352e-03
## ASV0153     -1.029344e-02 -1.076988e-02 -1.126745e-02 -1.178699e-02
## ASV0498      3.490963e-03  3.642773e-03  3.800440e-03  3.964118e-03
## ASV0097      2.023899e-03  2.117893e-03  2.216107e-03  2.318712e-03
## ASV0104     -1.318243e-02 -1.372379e-02 -1.428402e-02 -1.486349e-02
## ASV1282      4.291265e-03  4.449613e-03  4.611845e-03  4.777889e-03
## ASV3883     -4.135737e-03 -4.339496e-03 -4.553101e-03 -4.776978e-03
## ASV0801      1.864456e-03  1.946408e-03  2.031713e-03  2.120494e-03
## ASV1611     -9.045681e-03 -9.457635e-03 -9.887506e-03 -1.033600e-02
## ASV0227     -1.945629e-03 -2.053056e-03 -2.166498e-03 -2.286272e-03
## ASV0833      2.977127e-03  3.105990e-03  3.239880e-03  3.378949e-03
## ASV0718      1.326062e-02  1.383318e-02  1.442823e-02  1.504647e-02
## ASV1139      1.196103e-03  1.214308e-03  1.230539e-03  1.244532e-03
## ASV0766     -2.063227e-03 -2.165071e-03 -2.271833e-03 -2.383725e-03
## ASV2091      9.871261e-03  1.023951e-02  1.061766e-02  1.100568e-02
## ASV1238     -1.014784e-02 -1.060737e-02 -1.108707e-02 -1.158781e-02
## ASV9193     -1.391701e-03 -1.481562e-03 -1.577467e-03 -1.679813e-03
## ASV0290      1.112084e-03  1.142647e-03  1.173232e-03  1.203782e-03
## ASV0231      3.730120e-03  3.877375e-03  4.029277e-03  4.185883e-03
## ASV0185      2.696457e-03  2.838832e-03  2.988920e-03  3.147130e-03
## ASV2330      4.035570e-03  4.179595e-03  4.326994e-03  4.477730e-03
## ASV3119     -2.413902e-03 -2.539551e-03 -2.671854e-03 -2.811151e-03
## ASV2368     -5.374750e-03 -5.628633e-03 -5.894455e-03 -6.172774e-03
## ASV0122     -2.357659e-03 -2.453614e-03 -2.552881e-03 -2.655535e-03
## ASV1044      6.523198e-03  6.820765e-03  7.131331e-03  7.455415e-03
## ASV0160     -2.361063e-03 -2.446371e-03 -2.533803e-03 -2.623354e-03
## ASV0326      6.974146e-04  7.272789e-04  7.582418e-04  7.903255e-04
## ASV1388      1.228729e-02  1.278968e-02  1.330944e-02  1.384691e-02
## ASV0792      8.797033e-03  9.136196e-03  9.485443e-03  9.844863e-03
## ASV0036     -3.087544e-03 -3.230113e-03 -3.378937e-03 -3.534252e-03
## ASV2125      8.872808e-03  9.241409e-03  9.623208e-03  1.001852e-02
## ASV1075     -1.399467e-04 -1.466503e-04 -1.537317e-04 -1.612193e-04
## ASV0390      5.118643e-03  5.358117e-03  5.608600e-03  5.870582e-03
## ASV3790     -6.967722e-03 -7.274148e-03 -7.593069e-03 -7.924922e-03
## ASV1535     -2.272794e-03 -2.389397e-03 -2.512030e-03 -2.640986e-03
## ASV0263      8.355219e-03  8.710994e-03  9.080322e-03  9.463602e-03
## ASV0675      1.299946e-02  1.358218e-02  1.418950e-02  1.482232e-02
## ASV3348      1.133627e-03  1.189240e-03  1.247534e-03  1.308627e-03
## ASV0058     -3.616419e-03 -3.763082e-03 -3.914705e-03 -4.071381e-03
## ASV4142      4.885557e-03  5.071148e-03  5.262001e-03  5.458143e-03
## ASV0059     -2.881306e-03 -2.996027e-03 -3.114447e-03 -3.236623e-03
## ASV0013     -5.315482e-03 -5.540437e-03 -5.773827e-03 -6.015889e-03
## ASV0033     -2.671066e-03 -2.793723e-03 -2.921725e-03 -3.055273e-03
## ASV4354     -3.157504e-03 -3.294064e-03 -3.436132e-03 -3.583907e-03
## ASV0022     -2.253482e-03 -2.356941e-03 -2.464921e-03 -2.577598e-03
## ASV0134     -2.253817e-03 -2.364467e-03 -2.480555e-03 -2.602340e-03
## ASV0415      4.205858e-04  4.438267e-04  4.682808e-04  4.939963e-04
## ASV10103    -1.229142e-02 -1.284294e-02 -1.341777e-02 -1.401678e-02
## ASV1613      8.341263e-03  8.661929e-03  8.991909e-03  9.331245e-03
## ASV0135     -1.013128e-03 -1.048111e-03 -1.083779e-03 -1.120102e-03
## ASV0469     -1.103838e-02 -1.148449e-02 -1.194591e-02 -1.242301e-02
## ASV0471      6.904335e-03  7.194963e-03  7.496418e-03  7.809011e-03
## ASV0451     -1.477132e-03 -1.561978e-03 -1.651783e-03 -1.746817e-03
## ASV0747      4.003508e-03  4.176448e-03  4.356108e-03  4.542687e-03
## ASV1314     -4.262379e-03 -4.463611e-03 -4.674227e-03 -4.894652e-03
## ASV0425     -1.321710e-02 -1.371989e-02 -1.423716e-02 -1.476904e-02
## ASV0559     -3.471474e-03 -3.619347e-03 -3.773118e-03 -3.933016e-03
## ASV0148     -5.489993e-04 -5.560226e-04 -5.619489e-04 -5.666371e-04
## ASV0129      1.272135e-03  1.356915e-03  1.447489e-03  1.544233e-03
## ASV1072      7.754790e-04  7.973297e-04  8.190556e-04  8.405741e-04
## ASV2390      6.544282e-03  6.775731e-03  7.012085e-03  7.253183e-03
## ASV0548      4.725365e-03  4.922210e-03  5.126154e-03  5.337373e-03
## ASV0168     -2.363017e-03 -2.457594e-03 -2.555313e-03 -2.656235e-03
## ASV0066     -2.688575e-03 -2.797379e-03 -2.909812e-03 -3.025934e-03
## ASV0468     -1.475876e-03 -1.539563e-03 -1.605776e-03 -1.674599e-03
## ASV0172     -6.800482e-04 -6.990128e-04 -7.178762e-04 -7.365710e-04
## ASV0236      4.180078e-04  4.734619e-04  5.340428e-04  6.001244e-04
## ASV0250      4.414312e-03  4.636831e-03  4.870749e-03  5.116640e-03
## ASV0338      1.949548e-03  2.037655e-03  2.129354e-03  2.224749e-03
## ASV0450     -4.733633e-04 -5.019382e-04 -5.322965e-04 -5.645466e-04
## ASV0377      3.347292e-03  3.482240e-03  3.621672e-03  3.765666e-03
## ASV1022     -1.143108e-04 -1.164007e-04 -1.182604e-04 -1.198482e-04
## ASV6174     -1.444703e-04 -1.556179e-04 -1.676387e-04 -1.805947e-04
## ASV0786     -7.086380e-04 -7.528622e-04 -7.997917e-04 -8.495693e-04
## ASV0053     -3.754974e-03 -3.915505e-03 -4.082172e-03 -4.255151e-03
## ASV0697     -2.151666e-03 -2.235632e-03 -2.322249e-03 -2.411562e-03
## ASV0785      4.643754e-03  4.831674e-03  5.025945e-03  5.226695e-03
## ASV1967     -4.574288e-03 -4.757990e-03 -4.947929e-03 -5.144244e-03
## ASV0385      1.719556e-03  1.799727e-03  1.883403e-03  1.970704e-03
## ASV0295      4.636961e-04  4.955276e-04  5.295780e-04  5.659928e-04
## ASV0072     -3.525054e-03 -3.661612e-03 -3.802207e-03 -3.946862e-03
## ASV0157     -1.992160e-04 -1.889598e-04 -1.767177e-04 -1.622996e-04
## ASV0501      8.148009e-03  8.498573e-03  8.862632e-03  9.240568e-03
## ASV10729    -1.036122e-02 -1.081609e-02 -1.128938e-02 -1.178173e-02
## ASV1470      4.636101e-03  4.798133e-03  4.963502e-03  5.132094e-03
## ASV0050     -8.526799e-03 -8.873657e-03 -9.232332e-03 -9.603055e-03
## ASV0411     -2.078717e-03 -2.173979e-03 -2.273438e-03 -2.377265e-03
## ASV0549      3.282598e-03  3.429030e-03  3.581555e-03  3.740388e-03
## ASV0184      1.044044e-03  1.087776e-03  1.133185e-03  1.180329e-03
## ASV0705      1.988204e-03  2.064946e-03  2.143910e-03  2.225103e-03
## ASV1715      4.452274e-03  4.642000e-03  4.838934e-03  5.043282e-03
## ASV0603      7.374193e-04  7.724997e-04  8.093206e-04  8.479788e-04
## ASV0826      7.378877e-03  7.684740e-03  8.001602e-03  8.329743e-03
## ASV0034     -2.289590e-03 -2.379329e-03 -2.471838e-03 -2.567148e-03
## ASV0838      1.002261e-03  9.993567e-04  9.923245e-04  9.806921e-04
## ASV0614     -2.016137e-03 -2.099495e-03 -2.185834e-03 -2.275230e-03
## ASV0014     -5.379608e-03 -5.603934e-03 -5.836384e-03 -6.077162e-03
## ASV0585      1.299820e-04  1.045969e-04  7.580302e-05  4.332512e-05
## ASV0016     -5.619530e-03 -5.853853e-03 -6.096663e-03 -6.348172e-03
## ASV5394     -4.307038e-03 -4.492854e-03 -4.685901e-03 -4.886397e-03
## ASV0666      8.752428e-03  9.089028e-03  9.435604e-03  9.792244e-03
## ASV2085      1.351066e-03  1.357217e-03  1.359577e-03  1.357743e-03
## ASV0003     -3.826335e-03 -3.985543e-03 -4.150493e-03 -4.321328e-03
## ASV0346      2.075886e-03  2.171824e-03  2.271921e-03  2.376324e-03
## ASV0267      1.396146e-04  1.556331e-04  1.730185e-04  1.918567e-04
## ASV0353      3.237464e-03  3.384299e-03  3.537445e-03  3.697141e-03
## ASV2419      8.131930e-03  8.463645e-03  8.806820e-03  9.161702e-03
## ASV0447      4.764353e-03  4.981085e-03  5.207122e-03  5.442808e-03
## ASV0654      6.670492e-03  6.949414e-03  7.238451e-03  7.537851e-03
## ASV0151      1.082853e-03  1.141406e-03  1.203220e-03  1.268472e-03
## ASV0065     -2.540615e-03 -2.644286e-03 -2.751530e-03 -2.862423e-03
## ASV0527      6.305899e-03  6.567350e-03  6.838176e-03  7.118605e-03
## ASV4055     -1.153314e-03 -1.212796e-03 -1.275546e-03 -1.341759e-03
## ASV0166     -3.027633e-03 -3.143806e-03 -3.263384e-03 -3.386391e-03
## ASV0417     -1.147677e-03 -1.185360e-03 -1.223589e-03 -1.262316e-03
## ASV0078     -1.811714e-03 -1.882052e-03 -1.954464e-03 -2.028958e-03
## ASV0322     -1.729550e-04 -1.668311e-04 -1.591443e-04 -1.497181e-04
## ASV0156     -4.639534e-03 -4.844182e-03 -5.057268e-03 -5.279096e-03
## ASV0648     -1.014286e-02 -1.059366e-02 -1.106316e-02 -1.155204e-02
## ASV0407     -7.963981e-04 -8.343467e-04 -8.741021e-04 -9.157500e-04
## ASV2030     -1.613425e-03 -1.682748e-03 -1.755085e-03 -1.830593e-03
## ASV0300      1.255922e-03  1.314481e-03  1.375655e-03  1.439546e-03
## ASV1150      3.231697e-04  3.406200e-04  3.590023e-04  3.783599e-04
## ASV0958      3.911506e-03  4.097040e-03  4.291272e-03  4.494595e-03
## ASV0216     -3.904914e-03 -4.064904e-03 -4.230714e-03 -4.402529e-03
## ASV0446      6.243622e-03  6.519973e-03  6.807610e-03  7.106911e-03
## ASV0367     -4.019055e-03 -4.192765e-03 -4.373304e-03 -4.560890e-03
## ASV0200     -2.382136e-03 -2.484326e-03 -2.590439e-03 -2.700590e-03
## ASV0334     -1.020475e-03 -1.047632e-03 -1.074683e-03 -1.101562e-03
## ASV1311      1.320213e-03  1.360671e-03  1.401375e-03  1.442227e-03
## ASV0458      1.918903e-03  1.976334e-03  2.034100e-03  2.092083e-03
## ASV1371      4.222911e-04  4.430784e-04  4.648198e-04  4.875468e-04
## ASV0418      4.923804e-03  5.110856e-03  5.303309e-03  5.501204e-03
## ASV0004      7.061067e-04  7.323724e-04  7.593457e-04  7.870273e-04
## ASV1943      1.207206e-02  1.243165e-02  1.279439e-02  1.315977e-02
## ASV1495     -1.501594e-03 -1.595491e-03 -1.695457e-03 -1.801870e-03
## ASV0901     -4.662630e-03 -4.874667e-03 -5.095987e-03 -5.326974e-03
## ASV0628      2.109206e-03  2.181086e-03  2.254227e-03  2.328553e-03
## ASV0400      1.359815e-03  1.411557e-03  1.464705e-03  1.519246e-03
## ASV0116     -1.364648e-03 -1.426201e-03 -1.490397e-03 -1.557340e-03
## ASV0788      1.211538e-02  1.266532e-02  1.323917e-02  1.383788e-02
## ASV0117      9.351074e-04  9.800933e-04  1.027203e-03  1.076528e-03
## ASV3137     -2.574347e-04 -2.673927e-04 -2.776414e-04 -2.881810e-04
## ASV0001      7.498924e-04  7.771560e-04  8.050913e-04  8.336920e-04
## ASV1651      2.175803e-03  2.257823e-03  2.342149e-03  2.428794e-03
## ASV1692      1.004947e-02  1.050237e-02  1.097460e-02  1.146691e-02
## ASV0660      2.995194e-03  3.091524e-03  3.188890e-03  3.287110e-03
## ASV0508      1.446427e-04  1.490073e-04  1.534029e-04  1.578208e-04
## ASV1660     -2.205645e-03 -2.315559e-03 -2.430834e-03 -2.551701e-03
## ASV0233      3.005226e-03  3.134289e-03  3.268363e-03  3.407601e-03
## ASV1343     -5.696551e-03 -5.951829e-03 -6.217934e-03 -6.495280e-03
## ASV0209      2.517230e-03  2.609357e-03  2.703800e-03  2.800538e-03
## ASV0193     -2.972754e-03 -3.083557e-03 -3.197265e-03 -3.313859e-03
## ASV0357      1.486147e-03  1.567265e-03  1.653049e-03  1.743773e-03
## ASV0198      2.358582e-03  2.454220e-03  2.553165e-03  2.655496e-03
## ASV0007      6.440628e-04  6.662082e-04  6.887836e-04  7.117725e-04
## ASV1772     -8.886899e-04 -9.120634e-04 -9.348824e-04 -9.569813e-04
## ASV0009      5.161129e-04  5.327033e-04  5.495065e-04  5.664993e-04
## ASV0006     -7.102633e-04 -7.441132e-04 -7.795412e-04 -8.166150e-04
## ASV0011     -2.329058e-03 -2.431932e-03 -2.539027e-03 -2.650489e-03
## ASV0015      3.888015e-04  4.011564e-04  4.136485e-04  4.262575e-04
## ASV0017      4.402140e-04  4.544430e-04  4.688654e-04  4.834628e-04
## ASV0235     -2.171151e-03 -2.268144e-03 -2.369188e-03 -2.474430e-03
## ASV0382      1.684044e-03  1.757099e-03  1.832862e-03  1.911380e-03
## ASV2357      7.007256e-03  7.316727e-03  7.638970e-03  7.974447e-03
## ASV0567     -1.386964e-03 -1.450811e-03 -1.517590e-03 -1.587438e-03
## ASV0165      1.165374e-03  1.216338e-03  1.269328e-03  1.324407e-03
## ASV0005      1.633060e-03  1.700773e-03  1.770889e-03  1.843465e-03
## ASV0384     -3.956847e-05 -3.165360e-05 -2.261698e-05 -1.235715e-05
## ASV0002      2.919778e-04  3.033384e-04  3.150619e-04  3.271560e-04
## ASV3017      8.167838e-03  8.475332e-03  8.791301e-03  9.115756e-03
## ASV0091     -2.171078e-04 -2.263004e-04 -2.358830e-04 -2.458763e-04
## ASV0186     -3.321519e-03 -3.461082e-03 -3.605727e-03 -3.755576e-03
## ASV0370      1.708764e-03  1.777220e-03  1.847930e-03  1.920935e-03
## ASV0018      2.103555e-03  2.191581e-03  2.282805e-03  2.377305e-03
## ASV1377      2.010882e-02  2.088739e-02  2.168938e-02  2.251502e-02
## ASV0019      2.210578e-03  2.303355e-03  2.399529e-03  2.499186e-03
## ASV0023     -1.445192e-03 -1.510059e-03 -1.577644e-03 -1.648043e-03
## ASV2194      2.376177e-03  2.486996e-03  2.602892e-03  2.724089e-03
## ASV1155      8.436368e-03  8.768718e-03  9.112028e-03  9.466541e-03
## ASV0510     -2.066081e-03 -2.133524e-03 -2.202021e-03 -2.271514e-03
## ASV2371     -5.072939e-03 -5.271411e-03 -5.476204e-03 -5.687427e-03
## ASV0024     -1.790767e-03 -1.870607e-03 -1.953757e-03 -2.040330e-03
## ASV2452      4.798399e-03  4.963548e-03  5.131815e-03  5.303052e-03
## ASV2332     -1.479172e-02 -1.538609e-02 -1.600079e-02 -1.663633e-02
## ASV2591      4.658650e-03  4.892884e-03  5.138271e-03  5.395234e-03
## ASV0521      3.635201e-03  3.797468e-03  3.966534e-03  4.142649e-03
## ASV5542      3.463632e-03  3.615840e-03  3.774105e-03  3.938616e-03
## ASV0336     -5.869460e-04 -6.222470e-04 -6.596783e-04 -6.993573e-04
## ASV10102     6.402068e-03  6.684815e-03  6.979008e-03  7.285016e-03
## ASV16823    -8.766159e-03 -9.087815e-03 -9.418123e-03 -9.757125e-03
## ASV3104      4.533719e-02  4.700001e-02  4.870751e-02  5.045989e-02
## ASV0781      6.873474e-03  7.161215e-03  7.459565e-03  7.768822e-03
## ASV10899     4.812598e-03  5.064981e-03  5.330724e-03  5.610500e-03
## ASV11222    -1.542007e-02 -1.598563e-02 -1.656641e-02 -1.716246e-02
## ASV11327    -1.383815e-02 -1.434547e-02 -1.486641e-02 -1.540105e-02
## ASV12458    -1.540593e-02 -1.597048e-02 -1.655017e-02 -1.714508e-02
## ASV1636      9.120779e-03  9.480257e-03  9.851189e-03  1.023376e-02
## ASV1890     -6.684432e-03 -6.903854e-03 -7.127255e-03 -7.354513e-03
## ASV2898      1.225662e-02  1.274169e-02  1.324236e-02  1.375889e-02
## ASV8328      2.708356e-03  2.900772e-03  3.106507e-03  3.326390e-03
## ASV0709     -1.394568e-02 -1.451466e-02 -1.510312e-02 -1.571147e-02
## ASV0856      1.252833e-02  1.310384e-02  1.370445e-02  1.433111e-02
## ASV0909      4.375612e-03  4.624373e-03  4.887519e-03  5.165828e-03
## ASV0937     -8.658949e-03 -9.047673e-03 -9.453201e-03 -9.876225e-03
## ASV11390    -2.198134e-02 -2.278676e-02 -2.361379e-02 -2.446254e-02
## ASV11966     6.324738e-03  6.625833e-03  6.940679e-03  7.269822e-03
## ASV12990     3.959395e-03  4.110519e-03  4.265989e-03  4.425839e-03
## ASV14797     5.788483e-03  6.005676e-03  6.228935e-03  6.458299e-03
## ASV14904    -3.154072e-02 -3.269644e-02 -3.388318e-02 -3.510111e-02
## ASV15304     4.175780e-03  4.386616e-03  4.607835e-03  4.839884e-03
## ASV16696    -1.089485e-02 -1.129400e-02 -1.170386e-02 -1.212448e-02
## ASV1690      2.129377e-02  2.226557e-02  2.327843e-02  2.433370e-02
## ASV2029      1.366190e-02  1.421902e-02  1.479555e-02  1.539194e-02
## ASV2834      1.786442e-02  1.864072e-02  1.944759e-02  2.028596e-02
## ASV4003      1.586956e-02  1.664194e-02  1.745200e-02  1.830157e-02
## ASV4064      8.565336e-03  8.942742e-03  9.335371e-03  9.743719e-03
## ASV4294      5.809996e-03  6.108045e-03  6.421491e-03  6.751096e-03
## ASV4609      4.581871e-03  4.766124e-03  4.956673e-03  5.153679e-03
## ASV6283     -1.018926e-02 -1.056292e-02 -1.094665e-02 -1.134050e-02
## ASV6491     -1.459769e-02 -1.513277e-02 -1.568226e-02 -1.624623e-02
## ASV7453      8.456404e-03  8.863099e-03  9.288657e-03  9.733845e-03
## ASV7959      3.476423e-03  3.670007e-03  3.874447e-03  4.090308e-03
## ASV8219      1.261416e-01  1.307659e-01  1.355149e-01  1.403892e-01
## ASV8547     -1.306196e-02 -1.354059e-02 -1.403212e-02 -1.453660e-02
## ASV9319      6.542215e-03  6.841618e-03  7.154125e-03  7.480262e-03
## ASV9382     -2.555221e-02 -2.648845e-02 -2.744990e-02 -2.843671e-02
## ASV11516    -1.705901e-02 -1.768378e-02 -1.832536e-02 -1.898383e-02
## ASV14377    -1.231189e-02 -1.276260e-02 -1.322542e-02 -1.370042e-02
## ASV1867      1.073053e-02  1.120564e-02  1.170028e-02  1.221513e-02
## ASV1895      4.675702e-03  4.833755e-03  4.994323e-03  5.157200e-03
## ASV3168      6.112907e-03  6.338202e-03  6.569183e-03  6.805800e-03
## ASV4449      3.606262e-02  3.758293e-02  3.916105e-02  4.079881e-02
## ASV6596      8.462688e-03  8.883596e-03  9.325528e-03  9.789501e-03
## ASV7492     -5.055915e-04 -4.712424e-04 -4.314842e-04 -3.858872e-04
## ASV9854     -2.583308e-03 -2.675427e-03 -2.769920e-03 -2.866796e-03
## ASV6296      2.064999e-01  2.140568e-01  2.218168e-01  2.297809e-01
## ASV4201      2.017623e-03  2.164724e-03  2.322213e-03  2.490751e-03
## ASV0552      7.374151e-03  7.696971e-03  8.032707e-03  8.381774e-03
## ASV3671     -4.725587e-03 -4.924403e-03 -5.131139e-03 -5.346118e-03
## ASV3529     -5.780190e-04 -5.615756e-04 -5.418025e-04 -5.184628e-04
## ASV1060      2.062156e-03  2.160126e-03  2.262767e-03  2.370304e-03
## ASV0239     -2.317893e-03 -2.398087e-03 -2.479960e-03 -2.563474e-03
## ASV5711     -1.134138e-02 -1.179807e-02 -1.227051e-02 -1.275908e-02
## ASV4152     -1.671052e-02 -1.742633e-02 -1.816990e-02 -1.894207e-02
## ASV1461      7.557977e-03  7.824081e-03  8.096050e-03  8.373768e-03
## ASV2877      3.989943e-03  4.134434e-03  4.282381e-03  4.433735e-03
## ASV0012      7.504283e-04  7.822691e-04  8.153245e-04  8.496320e-04
## ASV9823      7.463584e-04  7.550531e-04  7.620669e-04  7.671797e-04
## ASV0008      7.930152e-04  8.262033e-04  8.606268e-04  8.963224e-04
## ASV7832     -9.947273e-03 -1.038270e-02 -1.083597e-02 -1.130772e-02
## ASV1915     -1.185062e-03 -1.233525e-03 -1.283927e-03 -1.336361e-03
## ASV0055     -9.986074e-04 -1.050053e-03 -1.104180e-03 -1.161121e-03
## ASV0032      3.169059e-04  3.249390e-04  3.328717e-04  3.406753e-04
## ASV2977     -1.378134e-02 -1.436581e-02 -1.497242e-02 -1.560183e-02
## ASV0466      1.002249e-02  1.037696e-02  1.073933e-02  1.110943e-02
## ASV3866      7.885343e-03  8.241130e-03  8.612193e-03  8.999129e-03
## ASV0040      2.775465e-03  2.895760e-03  3.020814e-03  3.150781e-03
## ASV0496     -1.087746e-03 -1.163136e-03 -1.243678e-03 -1.329683e-03
## ASV0052      2.334304e-03  2.435702e-03  2.541126e-03  2.650708e-03
## ASV3828     -7.280154e-03 -7.544180e-03 -7.815093e-03 -8.092911e-03
## ASV1930      3.869685e-03  4.016711e-03  4.167788e-03  4.322909e-03
## ASV2126      6.833347e-03  7.112492e-03  7.401419e-03  7.700367e-03
## ASV0793      8.862902e-03  9.257221e-03  9.667884e-03  1.009547e-02
## ASV0299     -2.068526e-04 -2.196569e-04 -2.334749e-04 -2.484032e-04
## ASV0208      6.285267e-03  6.558219e-03  6.842091e-03  7.137259e-03
## ASV0511     -2.254317e-03 -2.330177e-03 -2.407399e-03 -2.485929e-03
## ASV1123     -6.959092e-03 -7.205311e-03 -7.457226e-03 -7.714769e-03
## ASV0099      2.930724e-04  3.101400e-04  3.282915e-04  3.475995e-04
## ASV0752     -4.711438e-03 -4.931077e-03 -5.160584e-03 -5.400363e-03
## ASV0883      6.416659e-03  6.712378e-03  7.021035e-03  7.343118e-03
## ASV0683      8.273810e-03  8.648757e-03  9.039784e-03  9.447497e-03
## ASV4117     -1.279342e-02 -1.335145e-02 -1.393219e-02 -1.453645e-02
## ASV2172      6.237583e-04  6.366499e-04  6.488908e-04  6.603706e-04
## ASV0330     -2.419090e-03 -2.526183e-03 -2.637721e-03 -2.753869e-03
## ASV0728      1.156177e-02  1.204553e-02  1.254691e-02  1.306637e-02
## ASV0499      3.242484e-03  3.391173e-03  3.546401e-03  3.708430e-03
## ASV0120     -5.144585e-03 -5.360725e-03 -5.584759e-03 -5.816884e-03
## ASV1446      3.195104e-03  3.280138e-03  3.364478e-03  3.447819e-03
## ASV17171    -9.947966e-03 -1.037150e-02 -1.081159e-02 -1.126881e-02
## ASV0533      8.323301e-04  8.736621e-04  9.170339e-04  9.625393e-04
## ASV2495     -2.902470e-03 -3.058389e-03 -3.223004e-03 -3.396790e-03
## ASV5582      3.913955e-03  4.033941e-03  4.154950e-03  4.276772e-03
## ASV1488      1.646011e-03  1.707197e-03  1.769888e-03  1.834052e-03
## ASV0682      2.380458e-03  2.490572e-03  2.605570e-03  2.725644e-03
## ASV0068     -3.925531e-03 -4.092409e-03 -4.265526e-03 -4.445041e-03
## ASV1987     -1.043975e-02 -1.092958e-02 -1.144161e-02 -1.197674e-02
## ASV0035     -1.019105e-03 -1.083728e-03 -1.152692e-03 -1.226290e-03
## ASV7192     -5.844914e-03 -6.079250e-03 -6.321415e-03 -6.571562e-03
## ASV0873     -5.413914e-03 -5.938812e-03 -6.504180e-03 -7.112415e-03
## ASV4749     -1.073114e-03 -1.178134e-03 -1.291890e-03 -1.414988e-03
## ASV2174      3.644367e-03  3.760634e-03  3.878246e-03  3.997014e-03
## ASV1476     -4.584435e-03 -4.798626e-03 -5.022674e-03 -5.257013e-03
## ASV0740     -1.291937e-02 -1.351352e-02 -1.413400e-02 -1.478188e-02
## ASV0170     -2.418491e-03 -2.522519e-03 -2.630611e-03 -2.742899e-03
## ASV2466     -1.106041e-02 -1.154012e-02 -1.203907e-02 -1.255794e-02
## ASV1709      3.843655e-03  4.000091e-03  4.162537e-03  4.331251e-03
## ASV6170     -1.774942e-02 -1.854583e-02 -1.937595e-02 -2.024107e-02
## ASV3673      8.856104e-03  9.262546e-03  9.686871e-03  1.012979e-02
## ASV1745     -2.427225e-03 -2.547290e-03 -2.673284e-03 -2.805484e-03
##                                                                    
## (Intercept)  6.914261e-02  7.202705e-02  7.501512e-02  7.810926e-02
## ASV1236      1.280191e-02  1.328962e-02  1.379187e-02  1.430885e-02
## ASV0421      2.093963e-03  2.213113e-03  2.338907e-03  2.471659e-03
## ASV0691     -8.749426e-03 -9.010165e-03 -9.273351e-03 -9.538666e-03
## ASV0899      1.112328e-02  1.154390e-02  1.197626e-02  1.242039e-02
## ASV1004      2.572166e-02  2.670254e-02  2.771225e-02  2.875111e-02
## ASV1041     -1.039789e-02 -1.077786e-02 -1.116700e-02 -1.156518e-02
## ASV1058      1.602485e-02  1.663578e-02  1.726486e-02  1.791231e-02
## ASV12542     5.977162e-03  6.191320e-03  6.410895e-03  6.635904e-03
## ASV1294      1.495389e-02  1.552655e-02  1.611644e-02  1.672382e-02
## ASV13113     5.841039e-03  6.119981e-03  6.412071e-03  6.717900e-03
## ASV1318      1.487245e-02  1.543843e-02  1.602101e-02  1.662038e-02
## ASV2269     -2.553724e-02 -2.649106e-02 -2.747081e-02 -2.847652e-02
## ASV2542      1.384086e-02  1.445211e-02  1.508860e-02  1.575126e-02
## ASV2660     -1.007493e-02 -1.044695e-02 -1.082889e-02 -1.122077e-02
## ASV2737      3.261711e-03  3.370205e-03  3.480908e-03  3.593803e-03
## ASV2840      1.283443e-02  1.326946e-02  1.371278e-02  1.416411e-02
## ASV3053      6.755561e-02  6.999143e-02  7.248960e-02  7.505028e-02
## ASV3077      4.350500e-03  4.510687e-03  4.675333e-03  4.844489e-03
## ASV3134      9.082683e-03  9.502871e-03  9.941931e-03  1.040066e-02
## ASV3140      1.147890e-02  1.195856e-02  1.245566e-02  1.297064e-02
## ASV3579      4.686486e-03  4.920755e-03  5.166641e-03  5.424671e-03
## ASV6119     -6.986090e-03 -7.246967e-03 -7.514942e-03 -7.790024e-03
## ASV7557     -1.418902e-02 -1.471854e-02 -1.526245e-02 -1.582075e-02
## ASV8422      3.467346e-03  3.594222e-03  3.724577e-03  3.858449e-03
## ASV1086     -4.663572e-04 -4.795897e-04 -4.929930e-04 -5.065703e-04
## ASV1310      6.835513e-03  7.093592e-03  7.359025e-03  7.631863e-03
## ASV15750    -8.228111e-04 -8.466990e-04 -8.706269e-04 -8.945343e-04
## ASV16905    -2.917772e-03 -3.026671e-03 -3.138530e-03 -3.253352e-03
## ASV2033      1.409506e-02  1.472538e-02  1.538181e-02  1.606524e-02
## ASV2089      6.163368e-03  6.393989e-03  6.630916e-03  6.874159e-03
## ASV2127      2.012127e-02  2.088468e-02  2.167036e-02  2.247856e-02
## ASV2725      1.566611e-02  1.623412e-02  1.681662e-02  1.741358e-02
## ASV2804     -6.039153e-03 -6.264566e-03 -6.496113e-03 -6.733802e-03
## ASV3075      1.412846e-02  1.472037e-02  1.533491e-02  1.597284e-02
## ASV3327      2.025016e-02  2.113091e-02  2.204651e-02  2.299805e-02
## ASV3342      1.722648e-02  1.796723e-02  1.873691e-02  1.953643e-02
## ASV3532     -1.865382e-02 -1.943745e-02 -2.025060e-02 -2.109420e-02
## ASV3600      8.736719e-03  9.107034e-03  9.491432e-03  9.890340e-03
## ASV4013      1.563586e-02  1.625750e-02  1.689944e-02  1.756203e-02
## ASV4136      1.585684e-02  1.644302e-02  1.704544e-02  1.766425e-02
## ASV4195      6.161367e-02  6.391232e-02  6.627346e-02  6.869718e-02
## ASV4407     -2.379252e-02 -2.467961e-02 -2.559077e-02 -2.652604e-02
## ASV4717      3.752656e-03  3.871904e-03  3.993118e-03  4.116242e-03
## ASV6794      9.491673e-03  9.829094e-03  1.017508e-02  1.052968e-02
## ASV8324     -1.220828e-02 -1.266343e-02 -1.313093e-02 -1.361079e-02
## ASV8981      1.729233e-06  2.162950e-05  4.384225e-05  6.854725e-05
## ASV9859      5.454781e-03  5.739883e-03  6.040326e-03  6.356930e-03
## ASV0936      1.296834e-02  1.352131e-02  1.409505e-02  1.469012e-02
## ASV12683    -9.516637e-05 -1.026906e-04 -1.106092e-04 -1.189216e-04
## ASV1293      7.906744e-03  8.201858e-03  8.505145e-03  8.816648e-03
## ASV13055     3.522339e-05  5.092138e-05  6.831408e-05  8.752750e-05
## ASV17063    -6.323194e-03 -6.558569e-03 -6.800314e-03 -7.048440e-03
## ASV2228      5.153865e-03  5.345594e-03  5.542504e-03  5.744601e-03
## ASV2769      1.131628e-03  1.193133e-03  1.257851e-03  1.325919e-03
## ASV2803      5.266432e-03  5.445322e-03  5.627911e-03  5.814139e-03
## ASV2896      5.020687e-03  5.246028e-03  5.481172e-03  5.726536e-03
## ASV3062      6.509511e-03  6.823452e-03  7.152111e-03  7.496102e-03
## ASV3107      9.168791e-03  9.566576e-03  9.980309e-03  1.041054e-02
## ASV3265      1.125198e-02  1.166791e-02  1.209500e-02  1.253330e-02
## ASV3666      6.597827e-05  6.519340e-05  6.405686e-05  6.253148e-05
## ASV4497      3.964193e-03  4.117059e-03  4.274577e-03  4.436811e-03
## ASV6914     -7.906943e-04 -8.331669e-04 -8.778821e-04 -9.249421e-04
## ASV0576     -1.254806e-02 -1.296185e-02 -1.338310e-02 -1.381157e-02
## ASV0673      1.547418e-02  1.608235e-02  1.670985e-02  1.735700e-02
## ASV0772      7.312641e-03  7.609425e-03  7.916575e-03  8.234354e-03
## ASV0862      1.513267e-03  1.620767e-03  1.735301e-03  1.857234e-03
## ASV0898      6.192953e-03  6.472379e-03  6.763429e-03  7.066483e-03
## ASV0910      6.933361e-03  7.236958e-03  7.552845e-03  7.881446e-03
## ASV0964     -4.847167e-03 -5.012503e-03 -5.181189e-03 -5.353145e-03
## ASV10059     5.225654e-03  5.471034e-03  5.727549e-03  5.995654e-03
## ASV10263    -9.659143e-03 -1.002040e-02 -1.039159e-02 -1.077277e-02
## ASV1088      1.220682e-02  1.273600e-02  1.328663e-02  1.385950e-02
## ASV1101      1.373324e-02  1.424271e-02  1.476594e-02  1.530295e-02
## ASV1183      3.915601e-03  4.079242e-03  4.248939e-03  4.424869e-03
## ASV11956     3.255861e-03  3.362739e-03  3.471605e-03  3.582417e-03
## ASV12774    -4.924637e-05 -6.675600e-05 -8.604752e-05 -1.072416e-04
## ASV1321      1.814860e-02  1.895642e-02  1.979775e-02  2.067376e-02
## ASV13793    -6.657690e-03 -6.906540e-03 -7.162225e-03 -7.424765e-03
## ASV14482     3.575328e-04  3.683586e-04  3.794470e-04  3.908150e-04
## ASV15483     3.016678e-03  3.146764e-03  3.281883e-03  3.422182e-03
## ASV2062      1.323489e-02  1.376176e-02  1.430617e-02  1.486850e-02
## ASV2132      1.142528e-02  1.191576e-02  1.242517e-02  1.295408e-02
## ASV2413      9.980099e-03  1.036286e-02  1.075728e-02  1.116356e-02
## ASV2490      2.939584e-02  3.044244e-02  3.151446e-02  3.261177e-02
## ASV2594      4.126906e-03  4.304777e-03  4.489908e-03  4.682585e-03
## ASV2822     -1.759256e-02 -1.825165e-02 -1.892901e-02 -1.962471e-02
## ASV2863      1.846337e-02  1.914585e-02  1.984720e-02  2.056756e-02
## ASV2910      6.836066e-03  7.092522e-03  7.356257e-03  7.627334e-03
## ASV2980      7.942893e-03  8.259731e-03  8.587045e-03  8.925039e-03
## ASV3307      1.398356e-02  1.450672e-02  1.504432e-02  1.559640e-02
## ASV3474      1.056944e-02  1.104944e-02  1.155000e-02  1.207189e-02
## ASV3502      1.033674e-02  1.076474e-02  1.120826e-02  1.166774e-02
## ASV4236      1.361978e-02  1.408996e-02  1.457009e-02  1.506000e-02
## ASV4842     -1.687517e-03 -1.756286e-03 -1.827006e-03 -1.899644e-03
## ASV4894     -6.667034e-03 -6.916843e-03 -7.173584e-03 -7.437289e-03
## ASV5290      5.752906e-03  5.996810e-03  6.249851e-03  6.512279e-03
## ASV5501      3.482983e-03  3.631922e-03  3.786939e-03  3.948287e-03
## ASV5795      3.891898e-03  4.058669e-03  4.231843e-03  4.411607e-03
## ASV5987     -1.863346e-02 -1.933243e-02 -2.005088e-02 -2.078892e-02
## ASV6267     -2.098504e-02 -2.177174e-02 -2.258032e-02 -2.341090e-02
## ASV6862      8.174492e-03  8.468766e-03  8.770591e-03  9.079991e-03
## ASV7145      3.536982e-03  3.662770e-03  3.791995e-03  3.924720e-03
## ASV7673     -6.666821e-03 -6.916705e-03 -7.173539e-03 -7.437357e-03
## ASV7789      4.164796e-03  4.376616e-03  4.599253e-03  4.833228e-03
## ASV7809      5.363149e-04  5.754956e-04  6.173148e-04  6.619148e-04
## ASV8002     -8.421421e-03 -8.737289e-03 -9.061976e-03 -9.395529e-03
## ASV8205      3.816929e-03  3.979108e-03  4.147510e-03  4.322330e-03
## ASV9155     -2.051199e-03 -2.122430e-03 -2.195165e-03 -2.269369e-03
## ASV9221      1.436876e-03  1.527440e-03  1.623720e-03  1.726042e-03
## ASV9311     -1.350859e-02 -1.401542e-02 -1.453644e-02 -1.507173e-02
## ASV9557     -9.227212e-03 -9.573195e-03 -9.928843e-03 -1.029421e-02
## ASV9936     -1.859807e-02 -1.929499e-02 -2.001134e-02 -2.074723e-02
## ASV1445      1.222683e-02  1.274360e-02  1.327976e-02  1.383585e-02
## ASV4232      5.059057e-03  5.301794e-03  5.556292e-03  5.823130e-03
## ASV6479      2.330108e-03  2.469344e-03  2.617018e-03  2.773608e-03
## ASV0142     -7.933598e-03 -8.226992e-03 -8.528400e-03 -8.837871e-03
## ASV0378      4.270275e-03  4.469844e-03  4.678283e-03  4.895926e-03
## ASV1122      1.198642e-02  1.250245e-02  1.303861e-02  1.359554e-02
## ASV0123     -6.979826e-03 -7.236269e-03 -7.499571e-03 -7.769759e-03
## ASV2064      3.258133e-03  3.356532e-03  3.455567e-03  3.555035e-03
## ASV4459     -3.910378e-04 -3.999418e-04 -4.088252e-04 -4.176949e-04
## ASV0448      3.421876e-03  3.582304e-03  3.749936e-03  3.925058e-03
## ASV0397      6.765244e-03  7.039757e-03  7.323686e-03  7.617234e-03
## ASV0485      7.688662e-03  7.991291e-03  8.303704e-03  8.626084e-03
## ASV1566      1.152095e-02  1.198470e-02  1.246409e-02  1.295943e-02
## ASV1365      1.003189e-02  1.044547e-02  1.087348e-02  1.131622e-02
## ASV1065      1.423808e-02  1.482711e-02  1.543729e-02  1.606916e-02
## ASV0722     -8.102530e-04 -8.487442e-04 -8.891258e-04 -9.314979e-04
## ASV12660    -7.525171e-03 -7.800188e-03 -8.082515e-03 -8.372180e-03
## ASV0223      2.147006e-03  2.233315e-03  2.322605e-03  2.414956e-03
## ASV0229      3.474247e-03  3.625620e-03  3.783096e-03  3.946889e-03
## ASV0877      1.118067e-03  1.143739e-03  1.168320e-03  1.191584e-03
## ASV0983      7.534077e-03  7.823583e-03  8.121765e-03  8.428721e-03
## ASV0626      1.353577e-03  1.437744e-03  1.526883e-03  1.621230e-03
## ASV4146      3.143203e-04  3.194610e-04  3.237256e-04  3.269543e-04
## ASV4175     -9.960109e-03 -1.038491e-02 -1.082591e-02 -1.128357e-02
## ASV2082     -5.583103e-03 -5.889618e-03 -6.213431e-03 -6.555483e-03
## ASV2272      4.721396e-03  4.923059e-03  5.132615e-03  5.350329e-03
## ASV2245     -7.180599e-03 -7.490514e-03 -7.812491e-03 -8.146893e-03
## ASV0590     -5.535981e-03 -5.850731e-03 -6.183645e-03 -6.535706e-03
## ASV0217      1.103256e-03  1.192023e-03  1.287151e-03  1.389010e-03
## ASV0416      4.379986e-03  4.507704e-03  4.635947e-03  4.764447e-03
## ASV1056      7.126080e-03  7.443773e-03  7.774508e-03  8.118715e-03
## ASV7777     -9.625337e-03 -1.003430e-02 -1.045908e-02 -1.090021e-02
## ASV0455      1.691582e-03  1.760576e-03  1.831916e-03  1.905646e-03
## ASV0604      4.794933e-03  5.014524e-03  5.243556e-03  5.482372e-03
## ASV6100     -6.795326e-03 -7.094004e-03 -7.405017e-03 -7.728830e-03
## ASV11359    -1.420339e-02 -1.479907e-02 -1.541656e-02 -1.605641e-02
## ASV6604      2.092381e-03  2.187413e-03  2.286482e-03  2.389729e-03
## ASV5004     -4.999226e-03 -5.207253e-03 -5.422979e-03 -5.646633e-03
## ASV1483     -2.118811e-03 -2.204468e-03 -2.293046e-03 -2.384608e-03
## ASV9773     -6.486495e-03 -6.765441e-03 -7.055358e-03 -7.356614e-03
## ASV4059      5.852963e-04  6.433991e-04  7.061497e-04  7.738371e-04
## ASV1193      7.570178e-03  7.879141e-03  8.198912e-03  8.529751e-03
## ASV4610     -4.714098e-04 -4.513592e-04 -4.280146e-04 -4.011652e-04
## ASV0742     -8.866503e-05 -5.629985e-05 -2.025144e-05  1.971742e-05
## ASV1502     -7.520326e-04 -8.067903e-04 -8.652401e-04 -9.275830e-04
## ASV0195     -5.645980e-05 -7.240085e-05 -8.988088e-05 -1.089991e-04
## ASV1213      4.714884e-03  4.871204e-03  5.030295e-03  5.192043e-03
## ASV1648     -6.090037e-03 -6.357575e-03 -6.636233e-03 -6.926443e-03
## ASV6984     -5.714958e-03 -5.967343e-03 -6.230352e-03 -6.504411e-03
## ASV0396     -5.445389e-05 -4.349254e-05 -3.139367e-05 -1.811378e-05
## ASV4297      7.083869e-03  7.334226e-03  7.590388e-03  7.852293e-03
## ASV2622      1.146487e-02  1.190152e-02  1.235112e-02  1.281383e-02
## ASV3512      5.603612e-03  5.891295e-03  6.194033e-03  6.512596e-03
## ASV2411      8.825329e-03  9.224758e-03  9.641236e-03  1.007539e-02
## ASV2291     -4.898199e-03 -5.180142e-03 -5.478336e-03 -5.793627e-03
## ASV0807      1.114214e-02  1.159461e-02  1.206245e-02  1.254598e-02
## ASV1292      2.265114e-03  2.333033e-03  2.401553e-03  2.470580e-03
## ASV1035      9.631090e-03  9.992161e-03  1.036375e-02  1.074600e-02
## ASV0070      3.722152e-04  4.048520e-04  4.400374e-04  4.779389e-04
## ASV0255      8.019142e-04  8.234023e-04  8.445938e-04  8.653815e-04
## ASV0057     -2.483358e-03 -2.564926e-03 -2.647800e-03 -2.731897e-03
## ASV0077     -4.242856e-04 -4.315232e-04 -4.382731e-04 -4.444785e-04
## ASV0625      5.425592e-03  5.619860e-03  5.818862e-03  6.022571e-03
## ASV2464      3.680539e-02  3.812826e-02  3.948492e-02  4.087541e-02
## ASV1315      1.160387e-02  1.213477e-02  1.268872e-02  1.326659e-02
## ASV2673      9.984871e-03  1.044371e-02  1.092264e-02  1.142246e-02
## ASV2161      4.208863e-03  4.402390e-03  4.604516e-03  4.815599e-03
## ASV0337     -2.296629e-03 -2.395374e-03 -2.497961e-03 -2.604513e-03
## ASV7680     -1.509918e-02 -1.575563e-02 -1.643824e-02 -1.714787e-02
## ASV0611      8.472785e-03  8.844347e-03  9.231062e-03  9.633468e-03
## ASV3118     -9.230111e-03 -9.657951e-03 -1.010472e-02 -1.057116e-02
## ASV1284      1.154461e-03  1.090244e-03  1.014771e-03  9.270703e-04
## ASV0889      5.916372e-03  6.148718e-03  6.388672e-03  6.636408e-03
## ASV4649     -3.110195e-03 -3.240755e-03 -3.376206e-03 -3.516694e-03
## ASV1108     -7.106920e-03 -7.448643e-03 -7.806491e-03 -8.181168e-03
## ASV0738      4.350218e-03  4.582336e-03  4.827035e-03  5.084968e-03
## ASV0473     -1.013899e-03 -1.071732e-03 -1.132614e-03 -1.196659e-03
## ASV0598     -2.389472e-03 -2.525841e-03 -2.670237e-03 -2.823115e-03
## ASV0429      4.211839e-03  4.364070e-03  4.519967e-03  4.679484e-03
## ASV1549      9.240766e-03  9.666946e-03  1.011190e-02  1.057635e-02
## ASV1203      6.455697e-03  6.708298e-03  6.968818e-03  7.237372e-03
## ASV4532      1.741182e-04  1.760687e-04  1.778580e-04  1.794877e-04
## ASV0274      1.352331e-03  1.417868e-03  1.486329e-03  1.557805e-03
## ASV0163     -4.695260e-03 -4.863713e-03 -5.036499e-03 -5.213643e-03
## ASV1298      4.307089e-04  4.434408e-04  4.566005e-04  4.702458e-04
## ASV9424     -1.185279e-02 -1.237874e-02 -1.292671e-02 -1.349755e-02
## ASV0412      1.108005e-02  1.150794e-02  1.194895e-02  1.240326e-02
## ASV0284      1.887379e-03  1.933761e-03  1.979326e-03  2.023870e-03
## ASV0620     -2.965117e-03 -3.121752e-03 -3.286643e-03 -3.460188e-03
## ASV0153     -1.232936e-02 -1.289545e-02 -1.348615e-02 -1.410238e-02
## ASV0498      4.133955e-03  4.310100e-03  4.492693e-03  4.681870e-03
## ASV0097      2.425888e-03  2.537817e-03  2.654688e-03  2.776693e-03
## ASV0104     -1.546263e-02 -1.608180e-02 -1.672137e-02 -1.738172e-02
## ASV1282      4.947656e-03  5.121036e-03  5.297901e-03  5.478101e-03
## ASV3883     -5.011566e-03 -5.257314e-03 -5.514682e-03 -5.784139e-03
## ASV0801      2.212879e-03  2.309002e-03  2.409001e-03  2.513020e-03
## ASV1611     -1.080383e-02 -1.129177e-02 -1.180056e-02 -1.233101e-02
## ASV0227     -2.412708e-03 -2.546146e-03 -2.686944e-03 -2.835469e-03
## ASV0833      3.523350e-03  3.673237e-03  3.828766e-03  3.990093e-03
## ASV0718      1.568864e-02  1.635547e-02  1.704772e-02  1.776613e-02
## ASV1139      1.256009e-03  1.264671e-03  1.270201e-03  1.272264e-03
## ASV0766     -2.500966e-03 -2.623780e-03 -2.752395e-03 -2.887045e-03
## ASV2091      1.140355e-02  1.181122e-02  1.222862e-02  1.265563e-02
## ASV1238     -1.211047e-02 -1.265600e-02 -1.322537e-02 -1.381961e-02
## ASV9193     -1.789020e-03 -1.905531e-03 -2.029813e-03 -2.162359e-03
## ASV0290      1.234242e-03  1.264555e-03  1.294665e-03  1.324518e-03
## ASV0231      4.347247e-03  4.513415e-03  4.684427e-03  4.860314e-03
## ASV0185      3.313888e-03  3.489643e-03  3.674861e-03  3.870029e-03
## ASV2330      4.631755e-03  4.789016e-03  4.949453e-03  5.113001e-03
## ASV3119     -2.957798e-03 -3.112165e-03 -3.274639e-03 -3.445620e-03
## ASV2368     -6.464173e-03 -6.769261e-03 -7.088676e-03 -7.423083e-03
## ASV0122     -2.761648e-03 -2.871294e-03 -2.984544e-03 -3.101467e-03
## ASV1044      7.793553e-03  8.146297e-03  8.514219e-03  8.897905e-03
## ASV0160     -2.715012e-03 -2.808766e-03 -2.904603e-03 -3.002506e-03
## ASV0326      8.235510e-04  8.579372e-04  8.935014e-04  9.302584e-04
## ASV1388      1.440248e-02  1.497647e-02  1.556923e-02  1.618110e-02
## ASV0792      1.021453e-02  1.059450e-02  1.098483e-02  1.138553e-02
## ASV0036     -3.696300e-03 -3.865325e-03 -4.041578e-03 -4.225311e-03
## ASV2125      1.042764e-02  1.085089e-02  1.128855e-02  1.174092e-02
## ASV1075     -1.691449e-04 -1.775427e-04 -1.864504e-04 -1.959092e-04
## ASV0390      6.144571e-03  6.431095e-03  6.730706e-03  7.043977e-03
## ASV3790     -8.270151e-03 -8.629215e-03 -9.002580e-03 -9.390723e-03
## ASV1535     -2.776572e-03 -2.919102e-03 -3.068905e-03 -3.226316e-03
## ASV0263      9.861239e-03  1.027364e-02  1.070122e-02  1.114439e-02
## ASV0675      1.548158e-02  1.616824e-02  1.688327e-02  1.762769e-02
## ASV3348      1.372639e-03  1.439694e-03  1.509920e-03  1.583445e-03
## ASV0058     -4.233203e-03 -4.400257e-03 -4.572626e-03 -4.750390e-03
## ASV4142      5.659594e-03  5.866368e-03  6.078470e-03  6.295900e-03
## ASV0059     -3.362605e-03 -3.492442e-03 -3.626176e-03 -3.763848e-03
## ASV0013     -6.266861e-03 -6.526983e-03 -6.796494e-03 -7.075634e-03
## ASV0033     -3.194574e-03 -3.339837e-03 -3.491276e-03 -3.649108e-03
## ASV4354     -3.737596e-03 -3.897415e-03 -4.063582e-03 -4.236326e-03
## ASV0022     -2.695148e-03 -2.817753e-03 -2.945600e-03 -3.078876e-03
## ASV0134     -2.730094e-03 -2.864099e-03 -3.004650e-03 -3.152056e-03
## ASV0415      5.210216e-04  5.494051e-04  5.791947e-04  6.104377e-04
## ASV10103    -1.464087e-02 -1.529094e-02 -1.596794e-02 -1.667282e-02
## ASV1613      9.679959e-03  1.003805e-02  1.040551e-02  1.078229e-02
## ASV0135     -1.157052e-03 -1.194593e-03 -1.232689e-03 -1.271299e-03
## ASV0469     -1.291613e-02 -1.342565e-02 -1.395193e-02 -1.449534e-02
## ASV0471      8.133053e-03  8.468864e-03  8.816764e-03  9.177080e-03
## ASV0451     -1.847360e-03 -1.953706e-03 -2.066155e-03 -2.185021e-03
## ASV0747      4.736385e-03  4.937403e-03  5.145940e-03  5.362196e-03
## ASV1314     -5.125326e-03 -5.366710e-03 -5.619281e-03 -5.883536e-03
## ASV0425     -1.531561e-02 -1.587693e-02 -1.645306e-02 -1.704403e-02
## ASV0559     -4.099278e-03 -4.272157e-03 -4.451914e-03 -4.638827e-03
## ASV0148     -5.699355e-04 -5.716823e-04 -5.717045e-04 -5.698178e-04
## ASV0129      1.647546e-03  1.757844e-03  1.875567e-03  2.001178e-03
## ASV1072      8.617952e-04  8.826211e-04  9.029461e-04  9.226564e-04
## ASV2390      7.498841e-03  7.748848e-03  8.002965e-03  8.260928e-03
## ASV0548      5.556036e-03  5.782314e-03  6.016376e-03  6.258385e-03
## ASV0168     -2.760421e-03 -2.867930e-03 -2.978823e-03 -3.093155e-03
## ASV0066     -3.145801e-03 -3.269467e-03 -3.396979e-03 -3.528380e-03
## ASV0468     -1.746123e-03 -1.820439e-03 -1.897642e-03 -1.977827e-03
## ASV0172     -7.550244e-04 -7.731576e-04 -7.908858e-04 -8.081180e-04
## ASV0236      6.721004e-04  7.503840e-04  8.354081e-04  9.276256e-04
## ASV0250      5.375106e-03  5.646774e-03  5.932300e-03  6.232368e-03
## ASV0338      2.323938e-03  2.427020e-03  2.534089e-03  2.645237e-03
## ASV0450     -5.988022e-04 -6.351833e-04 -6.738158e-04 -7.148319e-04
## ASV0377      3.914291e-03  4.067614e-03  4.225696e-03  4.388592e-03
## ASV1022     -1.211178e-04 -1.220182e-04 -1.224926e-04 -1.224791e-04
## ASV6174     -1.945510e-04 -2.095754e-04 -2.257384e-04 -2.431131e-04
## ASV0786     -9.023419e-04 -9.582605e-04 -1.017480e-03 -1.080158e-03
## ASV0053     -4.434625e-03 -4.620772e-03 -4.813776e-03 -5.013817e-03
## ASV0697     -2.503617e-03 -2.598459e-03 -2.696133e-03 -2.796683e-03
## ASV0785      5.434045e-03  5.648115e-03  5.869022e-03  6.096877e-03
## ASV1967     -5.347075e-03 -5.556561e-03 -5.772839e-03 -5.996047e-03
## ASV0385      2.061753e-03  2.156672e-03  2.255583e-03  2.358606e-03
## ASV0295      6.049254e-04  6.465369e-04  6.909972e-04  7.384843e-04
## ASV0072     -4.095590e-03 -4.248397e-03 -4.405278e-03 -4.566221e-03
## ASV0157     -1.455024e-04 -1.261093e-04 -1.038893e-04 -7.859676e-05
## ASV0501      9.632766e-03  1.003961e-02  1.046148e-02  1.089874e-02
## ASV10729    -1.229378e-02 -1.282618e-02 -1.337959e-02 -1.395470e-02
## ASV1470      5.303780e-03  5.478411e-03  5.655822e-03  5.835827e-03
## ASV0050     -9.986054e-03 -1.038154e-02 -1.078974e-02 -1.121083e-02
## ASV0411     -2.485636e-03 -2.598736e-03 -2.716755e-03 -2.839889e-03
## ASV0549      3.905749e-03  4.077861e-03  4.256954e-03  4.443259e-03
## ASV0184      1.229271e-03  1.280076e-03  1.332810e-03  1.387547e-03
## ASV0705      2.308522e-03  2.394161e-03  2.482006e-03  2.572038e-03
## ASV1715      5.255252e-03  5.475054e-03  5.702898e-03  5.938995e-03
## ASV0603      8.885775e-04  9.312265e-04  9.760434e-04  1.023153e-03
## ASV0826      8.669443e-03  9.020980e-03  9.384636e-03  9.760688e-03
## ASV0034     -2.665285e-03 -2.766272e-03 -2.870127e-03 -2.976865e-03
## ASV0838      9.639498e-04  9.415481e-04  9.128961e-04  8.773589e-04
## ASV0614     -2.367756e-03 -2.463485e-03 -2.562490e-03 -2.664843e-03
## ASV0014     -6.326471e-03 -6.584510e-03 -6.851479e-03 -7.127575e-03
## ASV0585      6.873945e-06 -3.385353e-05 -7.917394e-05 -1.294172e-04
## ASV0016     -6.608593e-03 -6.878136e-03 -7.157007e-03 -7.445415e-03
## ASV5394     -5.094561e-03 -5.310614e-03 -5.534778e-03 -5.767274e-03
## ASV0666      1.015902e-02  1.053600e-02  1.092323e-02  1.132075e-02
## ASV2085      1.351291e-03  1.339770e-03  1.322705e-03  1.299595e-03
## ASV0003     -4.498190e-03 -4.681220e-03 -4.870557e-03 -5.066339e-03
## ASV0346      2.485182e-03  2.598643e-03  2.716857e-03  2.839975e-03
## ASV0267      2.122352e-04  2.342435e-04  2.579718e-04  2.835111e-04
## ASV0353      3.863633e-03  4.037172e-03  4.218016e-03  4.406428e-03
## ASV2419      9.528534e-03  9.907553e-03  1.029899e-02  1.070307e-02
## ASV0447      5.688497e-03  5.944551e-03  6.211339e-03  6.489236e-03
## ASV0654      7.847858e-03  8.168713e-03  8.500654e-03  8.843911e-03
## ASV0151      1.337346e-03  1.410032e-03  1.486729e-03  1.567644e-03
## ASV0065     -2.977039e-03 -3.095450e-03 -3.217727e-03 -3.343938e-03
## ASV0527      7.408866e-03  7.709187e-03  8.019789e-03  8.340896e-03
## ASV4055     -1.411644e-03 -1.485422e-03 -1.563331e-03 -1.645622e-03
## ASV0166     -3.512846e-03 -3.642765e-03 -3.776155e-03 -3.913021e-03
## ASV0417     -1.301486e-03 -1.341041e-03 -1.380915e-03 -1.421040e-03
## ASV0078     -2.105538e-03 -2.184200e-03 -2.264937e-03 -2.347735e-03
## ASV0322     -1.383616e-04 -1.248677e-04 -1.090132e-04 -9.055761e-05
## ASV0156     -5.509981e-03 -5.750249e-03 -6.000230e-03 -6.260267e-03
## ASV0648     -1.206098e-02 -1.259067e-02 -1.314184e-02 -1.371521e-02
## ASV0407     -9.593802e-04 -1.005086e-03 -1.052966e-03 -1.103122e-03
## ASV2030     -1.909437e-03 -1.991795e-03 -2.077858e-03 -2.167827e-03
## ASV0300      1.506258e-03  1.575898e-03  1.648574e-03  1.724397e-03
## ASV1150      3.987369e-04  4.201784e-04  4.427298e-04  4.664374e-04
## ASV0958      4.707419e-03  4.930168e-03  5.163287e-03  5.407233e-03
## ASV0216     -4.580537e-03 -4.764935e-03 -4.955931e-03 -5.153738e-03
## ASV0446      7.418261e-03  7.742050e-03  8.078674e-03  8.428531e-03
## ASV0367     -4.755745e-03 -4.958093e-03 -5.168162e-03 -5.386184e-03
## ASV0200     -2.814893e-03 -2.933459e-03 -3.056404e-03 -3.183839e-03
## ASV0334     -1.128200e-03 -1.154530e-03 -1.180479e-03 -1.205977e-03
## ASV1311      1.483127e-03  1.523959e-03  1.564603e-03  1.604926e-03
## ASV0458      2.150154e-03  2.208175e-03  2.265996e-03  2.323460e-03
## ASV1371      5.112902e-04  5.360800e-04  5.619452e-04  5.889129e-04
## ASV0418      5.704575e-03  5.913449e-03  6.127847e-03  6.347780e-03
## ASV0004      8.154165e-04  8.445116e-04  8.743093e-04  9.048053e-04
## ASV1943      1.352724e-02  1.389623e-02  1.426614e-02  1.463632e-02
## ASV1495     -1.915127e-03 -2.035646e-03 -2.163866e-03 -2.300246e-03
## ASV0901     -5.568024e-03 -5.819547e-03 -6.081969e-03 -6.355732e-03
## ASV0628      2.403975e-03  2.480396e-03  2.557709e-03  2.635794e-03
## ASV0400      1.575166e-03  1.632440e-03  1.691042e-03  1.750936e-03
## ASV0116     -1.627136e-03 -1.699895e-03 -1.775731e-03 -1.854761e-03
## ASV0788      1.446243e-02  1.511386e-02  1.579321e-02  1.650159e-02
## ASV0117      1.128165e-03  1.182212e-03  1.238769e-03  1.297942e-03
## ASV3137     -2.990111e-04 -3.101300e-04 -3.215352e-04 -3.332227e-04
## ASV0001      8.629498e-04  8.928548e-04  9.233955e-04  9.545581e-04
## ASV1651      2.517765e-03  2.609069e-03  2.702708e-03  2.798682e-03
## ASV1692      1.198004e-02  1.251479e-02  1.307196e-02  1.365236e-02
## ASV0660      3.385982e-03  3.485285e-03  3.584774e-03  3.684185e-03
## ASV0508      1.622510e-04  1.666829e-04  1.711047e-04  1.755034e-04
## ASV1660     -2.678397e-03 -2.811165e-03 -2.950254e-03 -3.095917e-03
## ASV0233      3.552163e-03  3.702208e-03  3.857897e-03  4.019395e-03
## ASV1343     -6.784293e-03 -7.085413e-03 -7.399094e-03 -7.725801e-03
## ASV0209      2.899544e-03  3.000787e-03  3.104228e-03  3.209818e-03
## ASV0193     -3.433310e-03 -3.555580e-03 -3.680620e-03 -3.808373e-03
## ASV0357      1.839726e-03  1.941215e-03  2.048563e-03  2.162110e-03
## ASV0198      2.761294e-03  2.870641e-03  2.983619e-03  3.100313e-03
## ASV0007      7.351559e-04  7.589131e-04  7.830211e-04  8.074549e-04
## ASV1772     -9.781757e-04 -9.982611e-04 -1.017011e-03 -1.034176e-03
## ASV0009      5.836565e-04  6.009509e-04  6.183530e-04  6.358315e-04
## ASV0006     -8.554046e-04 -8.959818e-04 -9.384208e-04 -9.827977e-04
## ASV0011     -2.766472e-03 -2.887129e-03 -3.012618e-03 -3.143101e-03
## ASV0015      4.389613e-04  4.517358e-04  4.645549e-04  4.773905e-04
## ASV0017      4.982150e-04  5.131001e-04  5.280944e-04  5.431726e-04
## ASV0235     -2.584021e-03 -2.698114e-03 -2.816869e-03 -2.940447e-03
## ASV0382      1.992698e-03  2.076853e-03  2.163873e-03  2.253782e-03
## ASV2357      8.323636e-03  8.687025e-03  9.065119e-03  9.458433e-03
## ASV0567     -1.660502e-03 -1.736936e-03 -1.816904e-03 -1.900575e-03
## ASV0165      1.381639e-03  1.441087e-03  1.502816e-03  1.566890e-03
## ASV0005      1.918553e-03  1.996205e-03  2.076471e-03  2.159400e-03
## ASV0384     -7.656647e-07  1.227320e-05  2.688283e-05  4.319456e-05
## ASV0002      3.396282e-04  3.524862e-04  3.657378e-04  3.793910e-04
## ASV3017      9.448689e-03  9.790074e-03  1.013987e-02  1.049801e-02
## ASV0091     -2.563026e-04 -2.671865e-04 -2.785546e-04 -2.904358e-04
## ASV0186     -3.910745e-03 -4.071351e-03 -4.237506e-03 -4.409315e-03
## ASV0370      1.996275e-03  2.073989e-03  2.154116e-03  2.236692e-03
## ASV0018      2.475162e-03  2.576450e-03  2.681247e-03  2.789626e-03
## ASV1377      2.336451e-02  2.423801e-02  2.513565e-02  2.605753e-02
## ASV0019      2.602411e-03  2.709290e-03  2.819907e-03  2.934345e-03
## ASV0023     -1.721355e-03 -1.797676e-03 -1.877109e-03 -1.959754e-03
## ASV2194      2.850819e-03  2.983326e-03  3.121860e-03  3.266685e-03
## ASV1155      9.832499e-03  1.021014e-02  1.059972e-02  1.100147e-02
## ASV0510     -2.341943e-03 -2.413246e-03 -2.485359e-03 -2.558217e-03
## ASV2371     -5.905183e-03 -6.129573e-03 -6.360693e-03 -6.598632e-03
## ASV0024     -2.130443e-03 -2.224214e-03 -2.321763e-03 -2.423211e-03
## ASV2452      5.477097e-03  5.653765e-03  5.832854e-03  6.014144e-03
## ASV2332     -1.729319e-02 -1.797187e-02 -1.867284e-02 -1.939662e-02
## ASV2591      5.664200e-03  5.945597e-03  6.239854e-03  6.547399e-03
## ASV0521      4.326068e-03  4.517053e-03  4.715874e-03  4.922805e-03
## ASV5542      4.109567e-03  4.287153e-03  4.471571e-03  4.663023e-03
## ASV0336     -7.414062e-04 -7.859524e-04 -8.331278e-04 -8.830696e-04
## ASV10102     7.603215e-03  7.933981e-03  8.277695e-03  8.634739e-03
## ASV16823    -1.010485e-02 -1.046132e-02 -1.082653e-02 -1.120050e-02
## ASV3104      5.225731e-02  5.409987e-02  5.598760e-02  5.792051e-02
## ASV0781      8.089287e-03  8.421268e-03  8.765074e-03  9.121020e-03
## ASV10899     5.905010e-03  6.214984e-03  6.541177e-03  6.884379e-03
## ASV11222    -1.777384e-02 -1.840059e-02 -1.904273e-02 -1.970025e-02
## ASV11327    -1.594942e-02 -1.651156e-02 -1.708748e-02 -1.767718e-02
## ASV12458    -1.775525e-02 -1.838072e-02 -1.902151e-02 -1.967762e-02
## ASV1636      1.062816e-02  1.103455e-02  1.145312e-02  1.188401e-02
## ASV1890     -7.585498e-03 -7.820073e-03 -8.058091e-03 -8.299399e-03
## ASV2898      1.429152e-02  1.484051e-02  1.540608e-02  1.598844e-02
## ASV8328      3.561288e-03  3.812111e-03  4.079807e-03  4.365370e-03
## ASV0709     -1.634009e-02 -1.698936e-02 -1.765964e-02 -1.835130e-02
## ASV0856      1.498481e-02  1.566655e-02  1.637734e-02  1.711823e-02
## ASV0909      5.460107e-03  5.771195e-03  6.099965e-03  6.447316e-03
## ASV0937     -1.031747e-02 -1.077768e-02 -1.125763e-02 -1.175813e-02
## ASV11390    -2.533308e-02 -2.622546e-02 -2.713970e-02 -2.807581e-02
## ASV11966     7.613818e-03  7.973239e-03  8.348664e-03  8.740684e-03
## ASV12990     4.590097e-03  4.758790e-03  4.931938e-03  5.109561e-03
## ASV14797     6.693799e-03  6.935459e-03  7.183300e-03  7.437334e-03
## ASV14904    -3.635031e-02 -3.763087e-02 -3.894283e-02 -4.028618e-02
## ASV15304     5.083224e-03  5.338326e-03  5.605672e-03  5.885753e-03
## ASV16696    -1.255592e-02 -1.299818e-02 -1.345129e-02 -1.391524e-02
## ASV1690      2.543277e-02  2.657703e-02  2.776787e-02  2.900667e-02
## ASV2029      1.600866e-02  1.664617e-02  1.730491e-02  1.798535e-02
## ASV2834      2.115678e-02  2.206099e-02  2.299955e-02  2.397341e-02
## ASV4003      1.919252e-02  2.012686e-02  2.110663e-02  2.213402e-02
## ASV4064      1.016829e-02  1.060959e-02  1.106813e-02  1.154444e-02
## ASV4294      7.097652e-03  7.461984e-03  7.844949e-03  8.247439e-03
## ASV4609      5.357310e-03  5.567737e-03  5.785140e-03  6.009702e-03
## ASV6283     -1.174452e-02 -1.215874e-02 -1.258317e-02 -1.301783e-02
## ASV6491     -1.682474e-02 -1.741784e-02 -1.802555e-02 -1.864788e-02
## ASV7453      1.019945e-02  1.068627e-02  1.119514e-02  1.172688e-02
## ASV7959      4.318183e-03  4.558686e-03  4.812456e-03  5.080158e-03
## ASV8219      1.453894e-01  1.505158e-01  1.557688e-01  1.611484e-01
## ASV8547     -1.505409e-02 -1.558463e-02 -1.612825e-02 -1.668496e-02
## ASV9319      7.820571e-03  8.175613e-03  8.545967e-03  8.932234e-03
## ASV9382     -2.944898e-02 -3.048678e-02 -3.155018e-02 -3.263921e-02
## ASV11516    -1.965927e-02 -2.035174e-02 -2.106126e-02 -2.178785e-02
## ASV14377    -1.418764e-02 -1.468713e-02 -1.519890e-02 -1.572297e-02
## ASV1867      1.275087e-02  1.330824e-02  1.388794e-02  1.449074e-02
## ASV1895      5.322157e-03  5.488938e-03  5.657267e-03  5.826837e-03
## ASV3168      7.047991e-03  7.295677e-03  7.548763e-03  7.807142e-03
## ASV4449      4.249805e-02  4.426068e-02  4.608863e-02  4.798391e-02
## ASV6596      1.027657e-02  1.078785e-02  1.132447e-02  1.188763e-02
## ASV7492     -3.340006e-04 -2.753530e-04 -2.094518e-04 -1.357838e-04
## ASV9854     -2.966064e-03 -3.067727e-03 -3.171789e-03 -3.278248e-03
## ASV6296      2.379498e-01  2.463244e-01  2.549049e-01  2.636916e-01
## ASV4201      2.671032e-03  2.863785e-03  3.069774e-03  3.289800e-03
## ASV0552      8.744591e-03  9.121582e-03  9.513174e-03  9.919797e-03
## ASV3671     -5.569684e-03 -5.802197e-03 -6.044037e-03 -6.295609e-03
## ASV3529     -4.913140e-04 -4.601084e-04 -4.245942e-04 -3.845161e-04
## ASV1060      2.482973e-03  2.601022e-03  2.724711e-03  2.854312e-03
## ASV0239     -2.648583e-03 -2.735239e-03 -2.823386e-03 -2.912964e-03
## ASV5711     -1.326417e-02 -1.378617e-02 -1.432547e-02 -1.488246e-02
## ASV4152     -1.974372e-02 -2.057574e-02 -2.143899e-02 -2.233439e-02
## ASV1461      8.657100e-03  8.945895e-03  9.239984e-03  9.539177e-03
## ASV2877      4.588435e-03  4.746409e-03  4.907571e-03  5.071827e-03
## ASV0012      8.852296e-04  9.221559e-04  9.604502e-04  1.000153e-03
## ASV9823      7.701545e-04  7.707367e-04  7.686531e-04  7.636115e-04
## ASV0008      9.333270e-04  9.716786e-04  1.011415e-03  1.052577e-03
## ASV7832     -1.179861e-02 -1.230933e-02 -1.284055e-02 -1.339300e-02
## ASV1915     -1.390924e-03 -1.447720e-03 -1.506860e-03 -1.568465e-03
## ASV0055     -1.221018e-03 -1.284014e-03 -1.350260e-03 -1.419914e-03
## ASV0032      3.483193e-04  3.557719e-04  3.630000e-04  3.699693e-04
## ASV2977     -1.625466e-02 -1.693159e-02 -1.763324e-02 -1.836028e-02
## ASV0466      1.148707e-02  1.187204e-02  1.226409e-02  1.266294e-02
## ASV3866      9.402559e-03  9.823120e-03  1.026147e-02  1.071830e-02
## ASV0040      3.285818e-03  3.426085e-03  3.571744e-03  3.722957e-03
## ASV0496     -1.421482e-03 -1.519414e-03 -1.623837e-03 -1.735117e-03
## ASV0052      2.764582e-03  2.882887e-03  3.005761e-03  3.133347e-03
## ASV3828     -8.377641e-03 -8.669283e-03 -8.967829e-03 -9.273259e-03
## ASV1930      4.482055e-03  4.645198e-03  4.812301e-03  4.983312e-03
## ASV2126      8.009578e-03  8.329295e-03  8.659763e-03  9.001229e-03
## ASV0793      1.054057e-02  1.100379e-02  1.148574e-02  1.198706e-02
## ASV0299     -2.645480e-04 -2.820256e-04 -3.009634e-04 -3.215005e-04
## ASV0208      7.444108e-03  7.763034e-03  8.094442e-03  8.438750e-03
## ASV0511     -2.565704e-03 -2.646662e-03 -2.728733e-03 -2.811846e-03
## ASV1123     -7.977856e-03 -8.246389e-03 -8.520255e-03 -8.799327e-03
## ASV0099      3.681411e-04  3.899980e-04  4.132574e-04  4.380113e-04
## ASV0752     -5.650831e-03 -5.912419e-03 -6.185570e-03 -6.470742e-03
## ASV0883      7.679127e-03  8.029572e-03  8.394972e-03  8.775854e-03
## ASV0683      9.872522e-03  1.031550e-02  1.077709e-02  1.125796e-02
## ASV4117     -1.516507e-02 -1.581894e-02 -1.649894e-02 -1.720598e-02
## ASV2172      6.709709e-04  6.805640e-04  6.890134e-04  6.961727e-04
## ASV0330     -2.874794e-03 -3.000673e-03 -3.131684e-03 -3.268014e-03
## ASV0728      1.360436e-02  1.416134e-02  1.473775e-02  1.533405e-02
## ASV0499      3.877528e-03  4.053973e-03  4.238051e-03  4.430054e-03
## ASV0120     -6.057290e-03 -6.306168e-03 -6.563704e-03 -6.830080e-03
## ASV1446      3.529828e-03  3.610151e-03  3.688405e-03  3.764180e-03
## ASV17171    -1.174375e-02 -1.223700e-02 -1.274919e-02 -1.328096e-02
## ASV0533      1.010276e-03  1.060343e-03  1.112846e-03  1.167891e-03
## ASV2495     -3.580242e-03 -3.773875e-03 -3.978226e-03 -4.193850e-03
## ASV5582      4.399179e-03  4.521927e-03  4.644753e-03  4.767377e-03
## ASV1488      1.899650e-03  1.966631e-03  2.034939e-03  2.104505e-03
## ASV0682      2.850994e-03  2.981824e-03  3.118342e-03  3.260762e-03
## ASV0068     -4.631116e-03 -4.823907e-03 -5.023567e-03 -5.230247e-03
## ASV1987     -1.253591e-02 -1.312009e-02 -1.373028e-02 -1.436748e-02
## ASV0035     -1.304833e-03 -1.388651e-03 -1.478093e-03 -1.573532e-03
## ASV7192     -6.829837e-03 -7.096381e-03 -7.371328e-03 -7.654806e-03
## ASV0873     -7.765993e-03 -8.467465e-03 -9.219453e-03 -1.002465e-02
## ASV4749     -1.548067e-03 -1.691795e-03 -1.846872e-03 -2.014030e-03
## ASV2174      4.116736e-03  4.237189e-03  4.358133e-03  4.479308e-03
## ASV1476     -5.502094e-03 -5.758384e-03 -6.026367e-03 -6.306545e-03
## ASV0740     -1.545828e-02 -1.616434e-02 -1.690127e-02 -1.767029e-02
## ASV0170     -2.859515e-03 -2.980596e-03 -3.106279e-03 -3.236708e-03
## ASV2466     -1.309740e-02 -1.365818e-02 -1.424097e-02 -1.484654e-02
## ASV1709      4.506509e-03  4.688607e-03  4.877862e-03  5.074615e-03
## ASV6170     -2.114247e-02 -2.208149e-02 -2.305950e-02 -2.407791e-02
## ASV3673      1.059204e-02  1.107437e-02  1.157756e-02  1.210241e-02
## ASV1745     -2.944177e-03 -3.089661e-03 -3.242246e-03 -3.402250e-03
##                                                                    
## (Intercept)  8.131192e-02  8.462548e-02  8.805230e-02  9.159468e-02
## ASV1236      1.484074e-02  1.538772e-02  1.594993e-02  1.652754e-02
## ASV0421      2.611688e-03  2.759322e-03  2.914891e-03  3.078729e-03
## ASV0691     -9.805779e-03 -1.007435e-02 -1.034401e-02 -1.061442e-02
## ASV0899      1.287632e-02  1.334403e-02  1.382351e-02  1.431470e-02
## ASV1004      2.981936e-02  3.091726e-02  3.204502e-02  3.320281e-02
## ASV1041     -1.197220e-02 -1.238785e-02 -1.281188e-02 -1.324399e-02
## ASV1058      1.857836e-02  1.926320e-02  1.996701e-02  2.068999e-02
## ASV12542     6.866359e-03  7.102269e-03  7.343644e-03  7.590490e-03
## ASV1294      1.734890e-02  1.799190e-02  1.865305e-02  1.933253e-02
## ASV13113     7.038082e-03  7.373253e-03  7.724074e-03  8.091227e-03
## ASV1318      1.723669e-02  1.787009e-02  1.852071e-02  1.918868e-02
## ASV2269     -2.950816e-02 -3.056566e-02 -3.164891e-02 -3.275772e-02
## ASV2542      1.644100e-02  1.715882e-02  1.790569e-02  1.868264e-02
## ASV2660     -1.162258e-02 -1.203432e-02 -1.245594e-02 -1.288741e-02
## ASV2737      3.708870e-03  3.826091e-03  3.945449e-03  4.066930e-03
## ASV2840      1.462314e-02  1.508951e-02  1.556285e-02  1.604275e-02
## ASV3053      7.767355e-02  8.035946e-02  8.310800e-02  8.591911e-02
## ASV3077      5.018206e-03  5.196537e-03  5.379532e-03  5.567244e-03
## ASV3134      1.087989e-02  1.138047e-02  1.190328e-02  1.244924e-02
## ASV3140      1.350393e-02  1.405596e-02  1.462718e-02  1.521799e-02
## ASV3579      5.695395e-03  5.979374e-03  6.277191e-03  6.589439e-03
## ASV6119     -8.072208e-03 -8.361480e-03 -8.657808e-03 -8.961150e-03
## ASV7557     -1.639345e-02 -1.698049e-02 -1.758183e-02 -1.819737e-02
## ASV8422      3.995878e-03  4.136901e-03  4.281559e-03  4.429892e-03
## ASV1086     -5.203270e-04 -5.342710e-04 -5.484135e-04 -5.627690e-04
## ASV1310      7.912149e-03  8.199919e-03  8.495197e-03  8.797997e-03
## ASV15750    -9.183562e-04 -9.420231e-04 -9.654605e-04 -9.885891e-04
## ASV16905    -3.371137e-03 -3.491877e-03 -3.615561e-03 -3.742169e-03
## ASV2033      1.677657e-02  1.751671e-02  1.828659e-02  1.908714e-02
## ASV2089      7.123717e-03  7.379577e-03  7.641716e-03  7.910097e-03
## ASV2127      2.330948e-02  2.416333e-02  2.504027e-02  2.594048e-02
## ASV2725      1.802497e-02  1.865074e-02  1.929079e-02  1.994503e-02
## ASV2804     -6.977633e-03 -7.227593e-03 -7.483658e-03 -7.745795e-03
## ASV3075      1.663497e-02  1.732213e-02  1.803517e-02  1.877497e-02
## ASV3327      2.398666e-02  2.501346e-02  2.607959e-02  2.718620e-02
## ASV3342      2.036674e-02  2.122879e-02  2.212356e-02  2.305203e-02
## ASV3532     -2.196918e-02 -2.287650e-02 -2.381715e-02 -2.479215e-02
## ASV3600      1.030419e-02  1.073341e-02  1.117846e-02  1.163976e-02
## ASV4013      1.824563e-02  1.895057e-02  1.967718e-02  2.042576e-02
## ASV4136      1.829958e-02  1.895154e-02  1.962024e-02  2.030578e-02
## ASV4195      7.118346e-02  7.373218e-02  7.634310e-02  7.901586e-02
## ASV4407     -2.748541e-02 -2.846882e-02 -2.947618e-02 -3.050733e-02
## ASV4717      4.241224e-03  4.368010e-03  4.496550e-03  4.626798e-03
## ASV6794      1.089295e-02  1.126493e-02  1.164567e-02  1.203523e-02
## ASV8324     -1.410301e-02 -1.460756e-02 -1.512440e-02 -1.565345e-02
## ASV8981      9.593359e-05  1.261997e-04  1.595536e-04  1.962126e-04
## ASV9859      6.690558e-03  7.042113e-03  7.412542e-03  7.802836e-03
## ASV0936      1.530707e-02  1.594643e-02  1.660875e-02  1.729453e-02
## ASV12683    -1.276239e-04 -1.367089e-04 -1.461652e-04 -1.559770e-04
## ASV1293      9.136400e-03  9.464423e-03  9.800729e-03  1.014532e-02
## ASV13055     1.086936e-04  1.319506e-04  1.574423e-04  1.853189e-04
## ASV17063    -7.302945e-03 -7.563817e-03 -7.831031e-03 -8.104552e-03
## ASV2228      5.951884e-03  6.164341e-03  6.381953e-03  6.604689e-03
## ASV2769      1.397471e-03  1.472643e-03  1.551573e-03  1.634396e-03
## ASV2803      6.003939e-03  6.197236e-03  6.393955e-03  6.594013e-03
## ASV2896      5.982553e-03  6.249676e-03  6.528377e-03  6.819148e-03
## ASV3062      7.856055e-03  8.232615e-03  8.626438e-03  9.038198e-03
## ASV3107      1.085785e-02  1.132280e-02  1.180600e-02  1.230805e-02
## ASV3265      1.298280e-02  1.344352e-02  1.391544e-02  1.439852e-02
## ASV3666      6.057764e-05  5.815327e-05  5.521383e-05  5.171229e-05
## ASV4497      4.603818e-03  4.775657e-03  4.952377e-03  5.134030e-03
## ASV6914     -9.744519e-04 -1.026519e-03 -1.081251e-03 -1.138761e-03
## ASV0576     -1.424699e-02 -1.468907e-02 -1.513751e-02 -1.559198e-02
## ASV0673      1.802410e-02  1.871145e-02  1.941934e-02  2.014804e-02
## ASV0772      8.563031e-03  8.902877e-03  9.254165e-03  9.617176e-03
## ASV0862      1.986932e-03  2.124770e-03  2.271126e-03  2.426381e-03
## ASV0898      7.381929e-03  7.710154e-03  8.051548e-03  8.406502e-03
## ASV0910      8.223191e-03  8.578523e-03  8.947891e-03  9.331755e-03
## ASV0964     -5.528284e-03 -5.706510e-03 -5.887718e-03 -6.071797e-03
## ASV10059     6.275818e-03  6.568521e-03  6.874258e-03  7.193533e-03
## ASV10263    -1.116394e-02 -1.156511e-02 -1.197627e-02 -1.239740e-02
## ASV1088      1.445542e-02  1.507523e-02  1.571981e-02  1.639006e-02
## ASV1101      1.585378e-02  1.641839e-02  1.699678e-02  1.758889e-02
## ASV1183      4.607209e-03  4.796141e-03  4.991851e-03  5.194527e-03
## ASV11956     3.695130e-03  3.809699e-03  3.926077e-03  4.044220e-03
## ASV12774    -1.304634e-04 -1.558422e-04 -1.835115e-04 -2.136086e-04
## ASV1321      2.158564e-02  2.253460e-02  2.352189e-02  2.454875e-02
## ASV13793    -7.694173e-03 -7.970449e-03 -8.253582e-03 -8.543552e-03
## ASV14482     4.024821e-04  4.144708e-04  4.268065e-04  4.395178e-04
## ASV15483     3.567808e-03  3.718909e-03  3.875632e-03  4.038125e-03
## ASV2062      1.544911e-02  1.604838e-02  1.666669e-02  1.730440e-02
## ASV2132      1.350307e-02  1.407271e-02  1.466357e-02  1.527625e-02
## ASV2413      1.158187e-02  1.201238e-02  1.245526e-02  1.291069e-02
## ASV2490      3.373424e-02  3.488169e-02  3.605390e-02  3.725061e-02
## ASV2594      4.883103e-03  5.091775e-03  5.308921e-03  5.534880e-03
## ASV2822     -2.033880e-02 -2.107132e-02 -2.182225e-02 -2.259156e-02
## ASV2863      2.130709e-02  2.206591e-02  2.284412e-02  2.364185e-02
## ASV2910      7.905810e-03  8.191737e-03  8.485160e-03  8.786119e-03
## ASV2980      9.273918e-03  9.633880e-03  1.000512e-02  1.038783e-02
## ASV3307      1.616302e-02  1.674417e-02  1.733985e-02  1.795003e-02
## ASV3474      1.261587e-02  1.318274e-02  1.377330e-02  1.438837e-02
## ASV3502      1.214361e-02  1.263631e-02  1.314628e-02  1.367398e-02
## ASV4236      1.555946e-02  1.606823e-02  1.658604e-02  1.711262e-02
## ASV4842     -1.974157e-03 -2.050491e-03 -2.128584e-03 -2.208360e-03
## ASV4894     -7.707979e-03 -7.985667e-03 -8.270355e-03 -8.562036e-03
## ASV5290      6.784345e-03  7.066302e-03  7.358402e-03  7.660899e-03
## ASV5501      4.116229e-03  4.291045e-03  4.473025e-03  4.662477e-03
## ASV5795      4.598149e-03  4.791656e-03  4.992319e-03  5.200325e-03
## ASV5987     -2.154661e-02 -2.232401e-02 -2.312113e-02 -2.393798e-02
## ASV6267     -2.426355e-02 -2.513834e-02 -2.603527e-02 -2.695435e-02
## ASV6862      9.396982e-03  9.721575e-03  1.005378e-02  1.039358e-02
## ASV7145      4.061015e-03  4.200954e-03  4.344615e-03  4.492081e-03
## ASV7673     -7.708186e-03 -7.986040e-03 -8.270925e-03 -8.562840e-03
## ASV7789      5.079084e-03  5.337381e-03  5.608700e-03  5.893643e-03
## ASV7809      7.094415e-04  7.600438e-04  8.138732e-04  8.710838e-04
## ASV8002     -9.737986e-03 -1.008937e-02 -1.044970e-02 -1.081898e-02
## ASV8205      4.503764e-03  4.692012e-03  4.887279e-03  5.089770e-03
## ASV9155     -2.345002e-03 -2.422020e-03 -2.500375e-03 -2.580014e-03
## ASV9221      1.834746e-03  1.950186e-03  2.072728e-03  2.202754e-03
## ASV9311     -1.562134e-02 -1.618534e-02 -1.676375e-02 -1.735658e-02
## ASV9557     -1.066934e-02 -1.105427e-02 -1.144901e-02 -1.185358e-02
## ASV9936     -2.150275e-02 -2.227796e-02 -2.307288e-02 -2.388755e-02
## ASV1445      1.441241e-02  1.501001e-02  1.562919e-02  1.627052e-02
## ASV4232      6.102913e-03  6.396278e-03  6.703893e-03  7.026458e-03
## ASV6479      2.939614e-03  3.115558e-03  3.301984e-03  3.499457e-03
## ASV0142     -9.155442e-03 -9.481145e-03 -9.815003e-03 -1.015703e-02
## ASV0378      5.123108e-03  5.360174e-03  5.607467e-03  5.865335e-03
## ASV1122      1.417390e-02  1.477432e-02  1.539748e-02  1.604406e-02
## ASV0123     -8.046850e-03 -8.330855e-03 -8.621777e-03 -8.919610e-03
## ASV2064      3.654716e-03  3.754373e-03  3.853751e-03  3.952576e-03
## ASV4459     -4.265629e-04 -4.354466e-04 -4.443704e-04 -4.533659e-04
## ASV0448      4.107958e-03  4.298936e-03  4.498294e-03  4.706343e-03
## ASV0397      7.920604e-03  8.233995e-03  8.557603e-03  8.891620e-03
## ASV0485      8.958616e-03  9.301477e-03  9.654845e-03  1.001889e-02
## ASV1566      1.347104e-02  1.399923e-02  1.454431e-02  1.510659e-02
## ASV1365      1.177399e-02  1.224705e-02  1.273568e-02  1.324011e-02
## ASV1065      1.672325e-02  1.740011e-02  1.810026e-02  1.882424e-02
## ASV0722     -9.759669e-04 -1.022645e-03 -1.071650e-03 -1.123108e-03
## ASV12660    -8.669203e-03 -8.973594e-03 -9.285357e-03 -9.604484e-03
## ASV0223      2.510445e-03  2.609153e-03  2.711164e-03  2.816560e-03
## ASV0229      4.117217e-03  4.294306e-03  4.478385e-03  4.669693e-03
## ASV0877      1.213281e-03  1.233140e-03  1.250864e-03  1.266132e-03
## ASV0983      8.744542e-03  9.069308e-03  9.403091e-03  9.745954e-03
## ASV0626      1.721027e-03  1.826517e-03  1.937950e-03  2.055574e-03
## ASV4146      3.289688e-04  3.295713e-04  3.285428e-04  3.256414e-04
## ASV4175     -1.175837e-02 -1.225079e-02 -1.276131e-02 -1.329041e-02
## ASV2082     -6.916758e-03 -7.298282e-03 -7.701123e-03 -8.126393e-03
## ASV2272      5.576475e-03  5.811331e-03  6.055183e-03  6.308323e-03
## ASV2245     -8.494092e-03 -8.854457e-03 -9.228362e-03 -9.616183e-03
## ASV0590     -6.907935e-03 -7.301399e-03 -7.717202e-03 -8.156495e-03
## ASV0217      1.497977e-03  1.614447e-03  1.738821e-03  1.871514e-03
## ASV0416      4.892918e-03  5.021053e-03  5.148528e-03  5.275000e-03
## ASV1056      8.476825e-03  8.849276e-03  9.236507e-03  9.638960e-03
## ASV7777     -1.135823e-02 -1.183369e-02 -1.232719e-02 -1.283930e-02
## ASV0455      1.981805e-03  2.060430e-03  2.141557e-03  2.225217e-03
## ASV0604      5.731320e-03  5.990754e-03  6.261031e-03  6.542518e-03
## ASV6100     -8.065924e-03 -8.416795e-03 -8.781960e-03 -9.161951e-03
## ASV11359    -1.671918e-02 -1.740541e-02 -1.811564e-02 -1.885040e-02
## ASV6604      2.497297e-03  2.609332e-03  2.725979e-03  2.847385e-03
## ASV5004     -5.878454e-03 -6.118683e-03 -6.367568e-03 -6.625366e-03
## ASV1483     -2.479218e-03 -2.576937e-03 -2.677826e-03 -2.781944e-03
## ASV9773     -7.669585e-03 -7.994655e-03 -8.332219e-03 -8.682682e-03
## ASV4059      8.467598e-04  9.252259e-04  1.009552e-03  1.100062e-03
## ASV1193      8.871919e-03  9.225680e-03  9.591295e-03  9.969026e-03
## ASV4610     -3.705979e-04 -3.360985e-04 -2.974527e-04 -2.544474e-04
## ASV0742      6.384926e-05  1.123911e-04  1.655937e-04  2.237101e-04
## ASV1502     -9.940257e-04 -1.064780e-03 -1.140060e-03 -1.220087e-03
## ASV0195     -1.298580e-04 -1.525635e-04 -1.772245e-04 -2.039530e-04
## ASV1213      5.356321e-03  5.522994e-03  5.691914e-03  5.862921e-03
## ASV1648     -7.228657e-03 -7.543342e-03 -7.870987e-03 -8.212097e-03
## ASV6984     -6.789965e-03 -7.087475e-03 -7.397423e-03 -7.720310e-03
## ASV0396     -3.613738e-06  1.214036e-05  2.917606e-05  4.751348e-05
## ASV4297      8.119870e-03  8.393033e-03  8.671687e-03  8.955725e-03
## ASV2622      1.328979e-02  1.377916e-02  1.428205e-02  1.479860e-02
## ASV3512      6.847795e-03  7.200472e-03  7.571509e-03  7.961825e-03
## ASV2411      1.052787e-02  1.099933e-02  1.149043e-02  1.200187e-02
## ASV2291     -6.126893e-03 -6.479039e-03 -6.851003e-03 -7.243748e-03
## ASV0807      1.304548e-02  1.356124e-02  1.409352e-02  1.464260e-02
## ASV1292      2.540014e-03  2.609754e-03  2.679694e-03  2.749726e-03
## ASV1035      1.113905e-02  1.154303e-02  1.195809e-02  1.238435e-02
## ASV0070      5.187318e-04  5.625995e-04  6.097329e-04  6.603311e-04
## ASV0255      8.856478e-04  9.052640e-04  9.240900e-04  9.419729e-04
## ASV0057     -2.817130e-03 -2.903402e-03 -2.990606e-03 -3.078631e-03
## ASV0077     -4.500808e-04 -4.550200e-04 -4.592352e-04 -4.626645e-04
## ASV0625      6.230951e-03  6.443958e-03  6.661536e-03  6.883625e-03
## ASV2464      4.229972e-02  4.375782e-02  4.524962e-02  4.677499e-02
## ASV1315      1.386928e-02  1.449770e-02  1.515278e-02  1.583548e-02
## ASV2673      1.194397e-02  1.248798e-02  1.305534e-02  1.364691e-02
## ASV2161      5.036005e-03  5.266118e-03  5.506330e-03  5.757051e-03
## ASV0337     -2.715153e-03 -2.830006e-03 -2.949201e-03 -3.072867e-03
## ASV7680     -1.788540e-02 -1.865172e-02 -1.944775e-02 -2.027441e-02
## ASV0611      1.005212e-02  1.048758e-02  1.094044e-02  1.141129e-02
## ASV3118     -1.105802e-02 -1.156609e-02 -1.209614e-02 -1.264899e-02
## ASV1284      8.261122e-04  7.108095e-04  5.800144e-04  4.325177e-04
## ASV0889      6.892098e-03  7.155920e-03  7.428054e-03  7.708687e-03
## ASV4649     -3.662369e-03 -3.813382e-03 -3.969890e-03 -4.132049e-03
## ASV1108     -8.573400e-03 -8.983934e-03 -9.413542e-03 -9.863018e-03
## ASV0738      5.356816e-03  5.643287e-03  5.945121e-03  6.263086e-03
## ASV0473     -1.263978e-03 -1.334678e-03 -1.408863e-03 -1.486631e-03
## ASV0598     -2.984954e-03 -3.156252e-03 -3.337532e-03 -3.529338e-03
## ASV0429      4.842566e-03  5.009144e-03  5.179141e-03  5.352466e-03
## ASV1549      1.106105e-02  1.156677e-02  1.209429e-02  1.264442e-02
## ASV1203      7.514068e-03  7.799009e-03  8.092289e-03  8.393994e-03
## ASV4532      1.809626e-04  1.822913e-04  1.834868e-04  1.845668e-04
## ASV0274      1.632383e-03  1.710151e-03  1.791189e-03  1.875577e-03
## ASV0163     -5.395168e-03 -5.581098e-03 -5.771454e-03 -5.966261e-03
## ASV1298      4.844443e-04  4.992748e-04  5.148282e-04  5.312088e-04
## ASV9424     -1.409211e-02 -1.471130e-02 -1.535602e-02 -1.602724e-02
## ASV0412      1.287106e-02  1.335250e-02  1.384774e-02  1.435692e-02
## ASV0284      2.067171e-03  2.108991e-03  2.149078e-03  2.187162e-03
## ASV0620     -3.642799e-03 -3.834903e-03 -4.036938e-03 -4.249357e-03
## ASV0153     -1.474509e-02 -1.541524e-02 -1.611379e-02 -1.684174e-02
## ASV0498      4.877760e-03  5.080483e-03  5.290151e-03  5.506866e-03
## ASV0097      2.904033e-03  3.036909e-03  3.175528e-03  3.320104e-03
## ASV0104     -1.806318e-02 -1.876608e-02 -1.949073e-02 -2.023743e-02
## ASV1282      5.661461e-03  5.847786e-03  6.036853e-03  6.228412e-03
## ASV3883     -6.066163e-03 -6.361240e-03 -6.669863e-03 -6.992530e-03
## ASV0801      2.621209e-03  2.733727e-03  2.850736e-03  2.972409e-03
## ASV1611     -1.288393e-02 -1.346014e-02 -1.406051e-02 -1.468590e-02
## ASV0227     -2.992103e-03 -3.157241e-03 -3.331289e-03 -3.514669e-03
## ASV0833      4.157373e-03  4.330765e-03  4.510424e-03  4.696507e-03
## ASV0718      1.851148e-02  1.928453e-02  2.008607e-02  2.091687e-02
## ASV1139      1.270505e-03  1.264548e-03  1.254002e-03  1.238450e-03
## ASV0766     -3.027971e-03 -3.175413e-03 -3.329620e-03 -3.490840e-03
## ASV2091      1.309215e-02  1.353803e-02  1.399310e-02  1.445717e-02
## ASV1238     -1.443978e-02 -1.508699e-02 -1.576242e-02 -1.646728e-02
## ASV9193     -2.303688e-03 -2.454345e-03 -2.614904e-03 -2.785965e-03
## ASV0290      1.354063e-03  1.383252e-03  1.412041e-03  1.440392e-03
## ASV0231      5.041100e-03  5.226798e-03  5.417414e-03  5.612944e-03
## ASV0185      4.075652e-03  4.292261e-03  4.520402e-03  4.760646e-03
## ASV2330      5.279586e-03  5.449131e-03  5.621552e-03  5.796764e-03
## ASV3119     -3.625525e-03 -3.814787e-03 -4.013855e-03 -4.223195e-03
## ASV2368     -7.773179e-03 -8.139689e-03 -8.523372e-03 -8.925021e-03
## ASV0122     -3.222134e-03 -3.346611e-03 -3.474967e-03 -3.607266e-03
## ASV1044      9.297961e-03  9.715011e-03  1.014970e-02  1.060268e-02
## ASV0160     -3.102457e-03 -3.204437e-03 -3.308427e-03 -3.414409e-03
## ASV0326      9.682206e-04  1.007397e-03  1.047795e-03  1.089417e-03
## ASV1388      1.681239e-02  1.746340e-02  1.813443e-02  1.882574e-02
## ASV0792      1.179662e-02  1.221810e-02  1.264995e-02  1.309213e-02
## ASV0036     -4.416780e-03 -4.616243e-03 -4.823960e-03 -5.040193e-03
## ASV2125      1.220828e-02  1.269090e-02  1.318905e-02  1.370297e-02
## ASV1075     -2.059640e-04 -2.166637e-04 -2.280619e-04 -2.402166e-04
## ASV0390      7.371501e-03  7.713898e-03  8.071810e-03  8.445903e-03
## ASV3790     -9.794130e-03 -1.021330e-02 -1.064873e-02 -1.110095e-02
## ASV1535     -3.391683e-03 -3.565363e-03 -3.747723e-03 -3.939138e-03
## ASV0263      1.160357e-02  1.207918e-02  1.257164e-02  1.308137e-02
## ASV0675      1.840252e-02  1.920880e-02  2.004762e-02  2.092005e-02
## ASV3348      1.660403e-03  1.740928e-03  1.825158e-03  1.913232e-03
## ASV0058     -4.933623e-03 -5.122393e-03 -5.316764e-03 -5.516793e-03
## ASV4142      6.518650e-03  6.746708e-03  6.980053e-03  7.218661e-03
## ASV0059     -3.905489e-03 -4.051130e-03 -4.200793e-03 -4.354496e-03
## ASV0013     -7.364643e-03 -7.663762e-03 -7.973230e-03 -8.293285e-03
## ASV0033     -3.813553e-03 -3.984833e-03 -4.163174e-03 -4.348802e-03
## ASV4354     -4.415881e-03 -4.602489e-03 -4.796398e-03 -4.997865e-03
## ASV0022     -3.217776e-03 -3.362494e-03 -3.513230e-03 -3.670184e-03
## ASV0134     -3.306637e-03 -3.468728e-03 -3.638677e-03 -3.816846e-03
## ASV0415      6.431807e-04  6.774689e-04  7.133466e-04  7.508561e-04
## ASV10103    -1.740655e-02 -1.817014e-02 -1.896460e-02 -1.979098e-02
## ASV1613      1.116834e-02  1.156355e-02  1.196782e-02  1.238101e-02
## ASV0135     -1.310377e-03 -1.349877e-03 -1.389744e-03 -1.429925e-03
## ASV0469     -1.505623e-02 -1.563500e-02 -1.623200e-02 -1.684763e-02
## ASV0471      9.550143e-03  9.936288e-03  1.033586e-02  1.074920e-02
## ASV0451     -2.310626e-03 -2.443303e-03 -2.583395e-03 -2.731252e-03
## ASV0747      5.586370e-03  5.818657e-03  6.059252e-03  6.308345e-03
## ASV1314     -6.159990e-03 -6.449180e-03 -6.751663e-03 -7.068015e-03
## ASV0425     -1.764985e-02 -1.827052e-02 -1.890600e-02 -1.955627e-02
## ASV0559     -4.833185e-03 -5.035295e-03 -5.245477e-03 -5.464070e-03
## ASV0148     -5.658260e-04 -5.595211e-04 -5.506826e-04 -5.390773e-04
## ASV0129      2.135161e-03  2.278025e-03  2.430300e-03  2.592541e-03
## ASV1072      9.416294e-04  9.597342e-04  9.768308e-04  9.927700e-04
## ASV2390      8.522443e-03  8.787188e-03  9.054812e-03  9.324933e-03
## ASV0548      6.508504e-03  6.766890e-03  7.033698e-03  7.309076e-03
## ASV0168     -3.210983e-03 -3.332363e-03 -3.457348e-03 -3.585991e-03
## ASV0066     -3.663707e-03 -3.802992e-03 -3.946260e-03 -4.093528e-03
## ASV0468     -2.061096e-03 -2.147551e-03 -2.237299e-03 -2.330449e-03
## ASV0172     -8.247568e-04 -8.406980e-04 -8.558308e-04 -8.700375e-04
## ASV0236      1.027509e-03  1.135552e-03  1.252266e-03  1.378184e-03
## ASV0250      6.547690e-03  6.879007e-03  7.227093e-03  7.592751e-03
## ASV0338      2.760551e-03  2.880112e-03  3.003996e-03  3.132273e-03
## ASV0450     -7.583704e-04 -8.045767e-04 -8.536031e-04 -9.056087e-04
## ASV0377      4.556350e-03  4.729011e-03  4.906608e-03  5.089167e-03
## ASV1022     -1.219091e-04 -1.207075e-04 -1.187924e-04 -1.160738e-04
## ASV6174     -2.617745e-04 -2.817999e-04 -3.032677e-04 -3.262571e-04
## ASV0786     -1.146455e-03 -1.216534e-03 -1.290561e-03 -1.368700e-03
## ASV0053     -5.221079e-03 -5.435742e-03 -5.657989e-03 -5.888000e-03
## ASV0697     -2.900153e-03 -3.006587e-03 -3.116031e-03 -3.228529e-03
## ASV0785      6.331788e-03  6.573860e-03  6.823192e-03  7.079880e-03
## ASV1967     -6.226320e-03 -6.463792e-03 -6.708597e-03 -6.960865e-03
## ASV0385      2.465859e-03  2.577458e-03  2.693516e-03  2.814141e-03
## ASV0295      7.891852e-04  8.432955e-04  9.010202e-04  9.625730e-04
## ASV0072     -4.731202e-03 -4.900185e-03 -5.073126e-03 -5.249965e-03
## ASV0157     -4.997077e-05 -1.773463e-05  1.840461e-05  5.875665e-05
## ASV0501      1.135178e-02  1.182095e-02  1.230660e-02  1.280907e-02
## ASV10729    -1.455218e-02 -1.517274e-02 -1.581708e-02 -1.648593e-02
## ASV1470      6.018224e-03  6.202788e-03  6.389275e-03  6.577420e-03
## ASV0050     -1.164501e-02 -1.209246e-02 -1.255334e-02 -1.302781e-02
## ASV0411     -2.968344e-03 -3.102329e-03 -3.242063e-03 -3.387773e-03
## ASV0549      4.637010e-03  4.838447e-03  5.047810e-03  5.265345e-03
## ASV0184      1.444358e-03  1.503323e-03  1.564525e-03  1.628048e-03
## ASV0705      2.664230e-03  2.758545e-03  2.854942e-03  2.953368e-03
## ASV1715      6.183554e-03  6.436785e-03  6.698897e-03  6.970098e-03
## ASV0603      1.072689e-03  1.124794e-03  1.179620e-03  1.237329e-03
## ASV0826      1.014942e-02  1.055110e-02  1.096601e-02  1.139443e-02
## ASV0034     -3.086496e-03 -3.199024e-03 -3.314449e-03 -3.432766e-03
## ASV0838      8.342554e-04  7.828560e-04  7.223798e-04  6.519928e-04
## ASV0614     -2.770616e-03 -2.879880e-03 -2.992704e-03 -3.109157e-03
## ASV0014     -7.412991e-03 -7.707917e-03 -8.012542e-03 -8.327046e-03
## ASV0585     -1.849263e-04 -2.460564e-04 -3.131744e-04 -3.866583e-04
## ASV0016     -7.743560e-03 -8.051644e-03 -8.369861e-03 -8.698404e-03
## ASV5394     -6.008323e-03 -6.258146e-03 -6.516959e-03 -6.784978e-03
## ASV0666      1.172856e-02  1.214667e-02  1.257507e-02  1.301374e-02
## ASV2085      1.269915e-03  1.233113e-03  1.188613e-03  1.135811e-03
## ASV0003     -5.268702e-03 -5.477780e-03 -5.693705e-03 -5.916604e-03
## ASV0346      2.968145e-03  3.101515e-03  3.240231e-03  3.384439e-03
## ASV0267      3.109521e-04  3.403847e-04  3.718972e-04  4.055750e-04
## ASV0353      4.602678e-03  4.807041e-03  5.019795e-03  5.241227e-03
## ASV2419      1.112002e-02  1.155003e-02  1.199330e-02  1.245003e-02
## ASV0447      6.778627e-03  7.079901e-03  7.393455e-03  7.719691e-03
## ASV0654      9.198712e-03  9.565275e-03  9.943815e-03  1.033454e-02
## ASV0151      1.652993e-03  1.742995e-03  1.837882e-03  1.937889e-03
## ASV0065     -3.474150e-03 -3.608425e-03 -3.746826e-03 -3.889411e-03
## ASV0527      8.672724e-03  9.015488e-03  9.369395e-03  9.734650e-03
## ASV4055     -1.732564e-03 -1.824443e-03 -1.921565e-03 -2.024253e-03
## ASV0166     -4.053359e-03 -4.197162e-03 -4.344415e-03 -4.495097e-03
## ASV0417     -1.461340e-03 -1.501735e-03 -1.542140e-03 -1.582463e-03
## ASV0078     -2.432574e-03 -2.519426e-03 -2.608256e-03 -2.699022e-03
## ASV0322     -6.924235e-05 -4.479003e-05 -1.690373e-05  1.473363e-05
## ASV0156     -6.530710e-03 -6.811919e-03 -7.104264e-03 -7.408124e-03
## ASV0648     -1.431151e-02 -1.493151e-02 -1.557597e-02 -1.624566e-02
## ASV0407     -1.155662e-03 -1.210697e-03 -1.268345e-03 -1.328726e-03
## ASV2030     -2.261921e-03 -2.360372e-03 -2.463426e-03 -2.571349e-03
## ASV0300      1.803479e-03  1.885935e-03  1.971879e-03  2.061426e-03
## ASV1150      4.913475e-04  5.175065e-04  5.449608e-04  5.737561e-04
## ASV0958      5.662483e-03  5.929534e-03  6.208897e-03  6.501104e-03
## ASV0216     -5.358581e-03 -5.570696e-03 -5.790331e-03 -6.017745e-03
## ASV0446      8.792024e-03  9.169560e-03  9.561545e-03  9.968389e-03
## ASV0367     -5.612392e-03 -5.847023e-03 -6.090314e-03 -6.342506e-03
## ASV0200     -3.315876e-03 -3.452624e-03 -3.594191e-03 -3.740683e-03
## ASV0334     -1.230951e-03 -1.255330e-03 -1.279045e-03 -1.302027e-03
## ASV1311      1.644784e-03  1.684026e-03  1.722485e-03  1.759988e-03
## ASV0458      2.380396e-03  2.436627e-03  2.491963e-03  2.546203e-03
## ASV1371      6.170087e-04  6.462560e-04  6.766757e-04  7.082857e-04
## ASV0418      6.573253e-03  6.804264e-03  7.040800e-03  7.282844e-03
## ASV0004      9.359939e-04  9.678680e-04  1.000419e-03  1.033638e-03
## ASV1943      1.500612e-02  1.537484e-02  1.574176e-02  1.610615e-02
## ASV1495     -2.445270e-03 -2.599441e-03 -2.763286e-03 -2.937356e-03
## ASV0901     -6.641293e-03 -6.939128e-03 -7.249727e-03 -7.573600e-03
## ASV0628      2.714521e-03  2.793749e-03  2.873324e-03  2.953080e-03
## ASV0400      1.812078e-03  1.874419e-03  1.937899e-03  2.002450e-03
## ASV0116     -1.937105e-03 -2.022886e-03 -2.112233e-03 -2.205275e-03
## ASV0788      1.724011e-02  1.800994e-02  1.881228e-02  1.964837e-02
## ASV0117      1.359837e-03  1.424564e-03  1.492234e-03  1.562964e-03
## ASV3137     -3.451871e-04 -3.574218e-04 -3.699180e-04 -3.826655e-04
## ASV0001      9.863275e-04  1.018686e-03  1.051616e-03  1.085095e-03
## ASV1651      2.896986e-03  2.997614e-03  3.100555e-03  3.205798e-03
## ASV1692      1.425685e-02  1.488629e-02  1.554157e-02  1.622361e-02
## ASV0660      3.783232e-03  3.881605e-03  3.978968e-03  4.074964e-03
## ASV0508      1.798648e-04  1.841733e-04  1.884120e-04  1.925622e-04
## ASV1660     -3.248410e-03 -3.407994e-03 -3.574932e-03 -3.749491e-03
## ASV0233      4.186867e-03  4.360480e-03  4.540403e-03  4.726806e-03
## ASV1343     -8.066017e-03 -8.420235e-03 -8.788964e-03 -9.172729e-03
## ASV0209      3.317504e-03  3.427224e-03  3.538908e-03  3.652478e-03
## ASV0193     -3.938768e-03 -4.071724e-03 -4.207150e-03 -4.344940e-03
## ASV0357      2.282212e-03  2.409247e-03  2.543611e-03  2.685719e-03
## ASV0198      3.220807e-03  3.345188e-03  3.473544e-03  3.605965e-03
## ASV0007      8.321874e-04  8.571894e-04  8.824299e-04  9.078757e-04
## ASV1772     -1.049479e-03 -1.062617e-03 -1.073256e-03 -1.081032e-03
## ASV0009      6.533531e-04  6.708822e-04  6.883819e-04  7.058129e-04
## ASV0006     -1.029191e-03 -1.077679e-03 -1.128346e-03 -1.181274e-03
## ASV0011     -3.278743e-03 -3.419709e-03 -3.566172e-03 -3.718304e-03
## ASV0015      4.902125e-04  5.029887e-04  5.156851e-04  5.282652e-04
## ASV0017      5.583076e-04  5.734706e-04  5.886310e-04  6.037567e-04
## ASV0235     -3.069014e-03 -3.202741e-03 -3.341801e-03 -3.486374e-03
## ASV0382      2.346592e-03  2.442306e-03  2.540915e-03  2.642398e-03
## ASV2357      9.867496e-03  1.029285e-02  1.073506e-02  1.119468e-02
## ASV0567     -1.988132e-03 -2.079762e-03 -2.175668e-03 -2.276059e-03
## ASV0165      1.633373e-03  1.702329e-03  1.773821e-03  1.847913e-03
## ASV0005      2.245039e-03  2.333434e-03  2.424625e-03  2.518654e-03
## ASV0384      6.134803e-05  8.149154e-05  1.037824e-04  1.283871e-04
## ASV0002      3.934538e-04  4.079346e-04  4.228418e-04  4.381842e-04
## ASV3017      1.086442e-02  1.123899e-02  1.162161e-02  1.201213e-02
## ASV0091     -3.028617e-04 -3.158668e-04 -3.294886e-04 -3.437681e-04
## ASV0186     -4.586883e-03 -4.770306e-03 -4.959675e-03 -5.155074e-03
## ASV0370      2.321754e-03  2.409338e-03  2.499479e-03  2.592211e-03
## ASV0018      2.901662e-03  3.017424e-03  3.136982e-03  3.260403e-03
## ASV1377      2.700369e-02  2.797417e-02  2.896894e-02  2.998794e-02
## ASV0019      3.052685e-03  3.175007e-03  3.301390e-03  3.431909e-03
## ASV0023     -2.045713e-03 -2.135090e-03 -2.227988e-03 -2.324511e-03
## ASV2194      3.418070e-03  3.576299e-03  3.741664e-03  3.914466e-03
## ASV1155      1.141564e-02  1.184248e-02  1.228223e-02  1.273516e-02
## ASV0510     -2.631754e-03 -2.705906e-03 -2.780610e-03 -2.855806e-03
## ASV2371     -6.843477e-03 -7.095307e-03 -7.354195e-03 -7.620209e-03
## ASV0024     -2.528680e-03 -2.638294e-03 -2.752176e-03 -2.870451e-03
## ASV2452      6.197393e-03  6.382339e-03  6.568702e-03  6.756182e-03
## ASV2332     -2.014370e-02 -2.091457e-02 -2.170974e-02 -2.252973e-02
## ASV2591      6.868658e-03  7.204051e-03  7.553993e-03  7.918891e-03
## ASV0521      5.138126e-03  5.362127e-03  5.595100e-03  5.837345e-03
## ASV5542      4.861712e-03  5.067843e-03  5.281624e-03  5.503267e-03
## ASV0336     -9.359202e-04 -9.918269e-04 -1.050942e-03 -1.113424e-03
## ASV10102     9.005497e-03  9.390353e-03  9.789688e-03  1.020388e-02
## ASV16823    -1.158321e-02 -1.197464e-02 -1.237475e-02 -1.278351e-02
## ASV3104      5.989853e-02  6.192154e-02  6.398938e-02  6.610184e-02
## ASV0781      9.489428e-03  9.870622e-03  1.026493e-02  1.067270e-02
## ASV10899     7.245404e-03  7.625099e-03  8.024339e-03  8.444031e-03
## ASV11222    -2.037314e-02 -2.106136e-02 -2.176487e-02 -2.248358e-02
## ASV11327    -1.828065e-02 -1.889784e-02 -1.952873e-02 -2.017323e-02
## ASV12458    -2.034902e-02 -2.103567e-02 -2.173753e-02 -2.245452e-02
## ASV1636      1.232738e-02  1.278339e-02  1.325218e-02  1.373387e-02
## ASV1890     -8.543838e-03 -8.791243e-03 -9.041448e-03 -9.294283e-03
## ASV2898      1.658781e-02  1.720439e-02  1.783835e-02  1.848989e-02
## ASV8328      4.669832e-03  4.994271e-03  5.339806e-03  5.707600e-03
## ASV0709     -1.906466e-02 -1.980007e-02 -2.055782e-02 -2.133822e-02
## ASV0856      1.789029e-02  1.869459e-02  1.953223e-02  2.040433e-02
## ASV0909      6.814183e-03  7.201528e-03  7.610344e-03  8.041652e-03
## ASV0937     -1.228003e-02 -1.282420e-02 -1.339153e-02 -1.398298e-02
## ASV11390    -2.903376e-02 -3.001350e-02 -3.101495e-02 -3.203802e-02
## ASV11966     9.149898e-03  9.576913e-03  1.002234e-02  1.048681e-02
## ASV12990     5.291676e-03  5.478296e-03  5.669433e-03  5.865098e-03
## ASV14797     7.697572e-03  7.964015e-03  8.236665e-03  8.515517e-03
## ASV14904    -4.166090e-02 -4.306691e-02 -4.450411e-02 -4.597237e-02
## ASV15304     6.179067e-03  6.486122e-03  6.807432e-03  7.143517e-03
## ASV16696    -1.439003e-02 -1.487563e-02 -1.537201e-02 -1.587912e-02
## ASV1690      3.029480e-02  3.163364e-02  3.302454e-02  3.446883e-02
## ASV2029      1.868793e-02  1.941312e-02  2.016135e-02  2.093308e-02
## ASV2834      2.498352e-02  2.603083e-02  2.711629e-02  2.824082e-02
## ASV4003      2.321128e-02  2.434077e-02  2.552496e-02  2.676641e-02
## ASV4064      1.203904e-02  1.255246e-02  1.308523e-02  1.363789e-02
## ASV4294      8.670380e-03  9.114729e-03  9.581481e-03  1.007167e-02
## ASV4609      6.241616e-03  6.481082e-03  6.728310e-03  6.983518e-03
## ASV6283     -1.346272e-02 -1.391781e-02 -1.438309e-02 -1.485852e-02
## ASV6491     -1.928483e-02 -1.993637e-02 -2.060248e-02 -2.128310e-02
## ASV7453      1.228235e-02  1.286241e-02  1.346793e-02  1.409981e-02
## ASV7959      5.362479e-03  5.660134e-03  5.973860e-03  6.304422e-03
## ASV8219      1.666546e-01  1.722873e-01  1.780463e-01  1.839311e-01
## ASV8547     -1.725476e-02 -1.783763e-02 -1.843355e-02 -1.904246e-02
## ASV9319      9.335032e-03  9.755001e-03  1.019280e-02  1.064911e-02
## ASV9382     -3.375385e-02 -3.489408e-02 -3.605986e-02 -3.725111e-02
## ASV11516    -2.253151e-02 -2.329223e-02 -2.406996e-02 -2.486466e-02
## ASV14377    -1.625934e-02 -1.680799e-02 -1.736890e-02 -1.794202e-02
## ASV1867      1.511738e-02  1.576864e-02  1.644531e-02  1.714819e-02
## ASV1895      5.997319e-03  6.168356e-03  6.339564e-03  6.510533e-03
## ASV3168      8.070689e-03  8.339263e-03  8.612711e-03  8.890863e-03
## ASV4449      4.994852e-02  5.198455e-02  5.409410e-02  5.627933e-02
## ASV6596      1.247857e-02  1.309857e-02  1.374896e-02  1.443112e-02
## ASV7492     -5.381483e-05  3.700968e-05  1.372644e-04  2.475438e-04
## ASV9854     -3.387101e-03 -3.498341e-03 -3.611958e-03 -3.727938e-03
## ASV6296      2.726844e-01  2.818832e-01  2.912875e-01  3.008967e-01
## ASV4201      3.524701e-03  3.775351e-03  4.042667e-03  4.327602e-03
## ASV0552      1.034188e-02  1.077986e-02  1.123416e-02  1.170521e-02
## ASV3671     -6.557337e-03 -6.829674e-03 -7.113097e-03 -7.408112e-03
## ASV3529     -3.396169e-04 -2.896381e-04 -2.343217e-04 -1.734108e-04
## ASV1060      2.990112e-03  3.132409e-03  3.281517e-03  3.437766e-03
## ASV0239     -3.003907e-03 -3.096145e-03 -3.189603e-03 -3.284200e-03
## ASV5711     -1.545753e-02 -1.605108e-02 -1.666349e-02 -1.729517e-02
## ASV4152     -2.326283e-02 -2.422521e-02 -2.522244e-02 -2.625541e-02
## ASV1461      9.843271e-03  1.015204e-02  1.046526e-02  1.078265e-02
## ASV2877      5.239066e-03  5.409166e-03  5.581992e-03  5.757396e-03
## ASV0012      1.041304e-03  1.083945e-03  1.128118e-03  1.173865e-03
## ASV9823      7.552998e-04  7.433855e-04  7.275150e-04  7.073129e-04
## ASV0008      1.095202e-03  1.139332e-03  1.185007e-03  1.232269e-03
## ASV7832     -1.396738e-02 -1.456444e-02 -1.518492e-02 -1.582959e-02
## ASV1915     -1.632659e-03 -1.699578e-03 -1.769366e-03 -1.842175e-03
## ASV0055     -1.493137e-03 -1.570098e-03 -1.650971e-03 -1.735936e-03
## ASV0032      3.766445e-04  3.829893e-04  3.889670e-04  3.945404e-04
## ASV2977     -1.911334e-02 -1.989307e-02 -2.070011e-02 -2.153509e-02
## ASV0466      1.306828e-02  1.347977e-02  1.389705e-02  1.431971e-02
## ASV3866      1.119431e-02  1.169022e-02  1.220679e-02  1.274479e-02
## ASV0040      3.879893e-03  4.042718e-03  4.211604e-03  4.386720e-03
## ASV0496     -1.853638e-03 -1.979795e-03 -2.113993e-03 -2.256652e-03
## ASV0052      3.265790e-03  3.403237e-03  3.545838e-03  3.693745e-03
## ASV3828     -9.585547e-03 -9.904659e-03 -1.023055e-02 -1.056317e-02
## ASV1930      5.158172e-03  5.336807e-03  5.519134e-03  5.705056e-03
## ASV2126      9.353939e-03  9.718145e-03  1.009410e-02  1.048205e-02
## ASV0793      1.250837e-02  1.305034e-02  1.361362e-02  1.419888e-02
## ASV0299     -3.437893e-04 -3.679954e-04 -3.942996e-04 -4.228980e-04
## ASV0208      8.796384e-03  9.167783e-03  9.553396e-03  9.953685e-03
## ASV0511     -2.895928e-03 -2.980902e-03 -3.066693e-03 -3.153222e-03
## ASV1123     -9.083462e-03 -9.372501e-03 -9.666269e-03 -9.964575e-03
## ASV0099      4.643576e-04  4.923993e-04  5.222457e-04  5.540118e-04
## ASV0752     -6.768406e-03 -7.079045e-03 -7.403160e-03 -7.741261e-03
## ASV0883      9.172755e-03  9.586214e-03  1.001678e-02  1.046500e-02
## ASV0683      1.175881e-02  1.228033e-02  1.282326e-02  1.338831e-02
## ASV4117     -1.794102e-02 -1.870503e-02 -1.949898e-02 -2.032392e-02
## ASV2172      7.018858e-04  7.059863e-04  7.082969e-04  7.086294e-04
## ASV0330     -3.409853e-03 -3.557397e-03 -3.710850e-03 -3.870421e-03
## ASV0728      1.595069e-02  1.658812e-02  1.724677e-02  1.792711e-02
## ASV0499      4.630284e-03  4.839051e-03  5.056672e-03  5.283471e-03
## ASV0120     -7.105474e-03 -7.390057e-03 -7.683995e-03 -7.987445e-03
## ASV1446      3.837038e-03  3.906514e-03  3.972109e-03  4.033297e-03
## ASV17171    -1.383297e-02 -1.440589e-02 -1.500043e-02 -1.561731e-02
## ASV0533      1.225587e-03  1.286049e-03  1.349391e-03  1.415734e-03
## ASV2495     -4.421326e-03 -4.661251e-03 -4.914241e-03 -5.180933e-03
## ASV5582      4.889501e-03  5.010811e-03  5.130971e-03  5.249630e-03
## ASV1488      2.175253e-03  2.247093e-03  2.319924e-03  2.393635e-03
## ASV0682      3.409303e-03  3.564188e-03  3.725644e-03  3.893901e-03
## ASV0068     -5.444092e-03 -5.665242e-03 -5.893831e-03 -6.129984e-03
## ASV1987     -1.503275e-02 -1.572716e-02 -1.645180e-02 -1.720780e-02
## ASV0035     -1.675360e-03 -1.783991e-03 -1.899867e-03 -2.023449e-03
## ASV7192     -7.946935e-03 -8.247827e-03 -8.557583e-03 -8.876297e-03
## ASV0873     -1.088581e-02 -1.180573e-02 -1.278729e-02 -1.383340e-02
## ASV4749     -2.194032e-03 -2.387673e-03 -2.595778e-03 -2.819205e-03
## ASV2174      4.600438e-03  4.721223e-03  4.841348e-03  4.960475e-03
## ASV1476     -6.599433e-03 -6.905565e-03 -7.225492e-03 -7.559779e-03
## ASV0740     -1.847266e-02 -1.930971e-02 -2.018277e-02 -2.109325e-02
## ASV0170     -3.372024e-03 -3.512376e-03 -3.657913e-03 -3.808787e-03
## ASV2466     -1.547563e-02 -1.612903e-02 -1.680753e-02 -1.751193e-02
## ASV1709      5.279234e-03  5.492114e-03  5.713680e-03  5.944390e-03
## ASV6170     -2.513815e-02 -2.624169e-02 -2.739003e-02 -2.858471e-02
## ASV3673      1.264973e-02  1.322036e-02  1.381515e-02  1.443499e-02
## ASV1745     -3.570002e-03 -3.745842e-03 -3.930119e-03 -4.123192e-03
##                                                                    
## (Intercept)  9.525487e-02  9.903507e-02  1.025671e-01  1.065688e-01
## ASV1236      1.712066e-02  1.772944e-02  1.815710e-02  1.880074e-02
## ASV0421      3.251174e-03  3.432564e-03  3.637516e-03  3.845996e-03
## ASV0691     -1.088519e-02 -1.115595e-02 -1.123820e-02 -1.148704e-02
## ASV0899      1.481753e-02  1.533193e-02  1.568120e-02  1.621314e-02
## ASV1004      3.439079e-02  3.560909e-02  3.649733e-02  3.775270e-02
## ASV1041     -1.368386e-02 -1.413113e-02 -1.440330e-02 -1.486602e-02
## ASV1058      2.143229e-02  2.219406e-02  2.277125e-02  2.355716e-02
## ASV12542     7.842815e-03  8.100627e-03  8.269763e-03  8.524950e-03
## ASV1294      2.003056e-02  2.074731e-02  2.129467e-02  2.204082e-02
## ASV13113     8.475422e-03  8.877392e-03  9.303974e-03  9.740943e-03
## ASV1318      1.987409e-02  2.057704e-02  2.109905e-02  2.183457e-02
## ASV2269     -3.389187e-02 -3.505107e-02 -3.586870e-02 -3.714705e-02
## ASV2542      1.949071e-02  2.033096e-02  2.115084e-02  2.206055e-02
## ASV2660     -1.332865e-02 -1.377960e-02 -1.411446e-02 -1.459854e-02
## ASV2737      4.190523e-03  4.316220e-03  4.372582e-03  4.485089e-03
## ASV2840      1.652878e-02  1.702048e-02  1.730130e-02  1.778906e-02
## ASV3053      8.879271e-02  9.172868e-02  9.397902e-02  9.698490e-02
## ASV3077      5.759726e-03  5.957033e-03  6.116489e-03  6.313645e-03
## ASV3134      1.301931e-02  1.361446e-02  1.422565e-02  1.487049e-02
## ASV3140      1.582882e-02  1.646007e-02  1.701710e-02  1.769687e-02
## ASV3579      6.916729e-03  7.259687e-03  7.627913e-03  7.997102e-03
## ASV6119     -9.271446e-03 -9.588623e-03 -9.821752e-03 -1.016471e-02
## ASV7557     -1.882698e-02 -1.947052e-02 -1.996183e-02 -2.065628e-02
## ASV8422      4.581944e-03  4.737759e-03  4.831795e-03  4.984399e-03
## ASV1086     -5.773558e-04 -5.921963e-04 -6.069078e-04 -6.168300e-04
## ASV1310      9.108326e-03  9.426178e-03  9.658074e-03  9.983851e-03
## ASV15750    -1.011325e-03 -1.033579e-03 -1.041895e-03 -1.067163e-03
## ASV16905    -3.871679e-03 -4.004060e-03 -4.106224e-03 -4.247242e-03
## ASV2033      1.991931e-02  2.078405e-02  2.160329e-02  2.252576e-02
## ASV2089      8.184669e-03  8.465372e-03  8.678170e-03  8.976261e-03
## ASV2127      2.686410e-02  2.781126e-02  2.853885e-02  2.951967e-02
## ASV2725      2.061333e-02  2.129555e-02  2.175515e-02  2.244912e-02
## ASV2804     -8.013954e-03 -8.288077e-03 -8.502009e-03 -8.792133e-03
## ASV3075      1.954246e-02  2.033858e-02  2.107126e-02  2.192056e-02
## ASV3327      2.833445e-02  2.952550e-02  3.061236e-02  3.187836e-02
## ASV3342      2.401521e-02  2.501411e-02  2.594290e-02  2.701423e-02
## ASV3532     -2.580254e-02 -2.684939e-02 -2.784538e-02 -2.897564e-02
## ASV3600      1.211778e-02  1.261298e-02  1.306008e-02  1.358509e-02
## ASV4013      2.119660e-02  2.198999e-02  2.264382e-02  2.347160e-02
## ASV4136      2.100825e-02  2.172772e-02  2.226751e-02  2.301512e-02
## ASV4195      8.174996e-02  8.454481e-02  8.681081e-02  8.975243e-02
## ASV4407     -3.156210e-02 -3.264025e-02 -3.354423e-02 -3.467877e-02
## ASV4717      4.758713e-03  4.892260e-03  4.913121e-03  5.038141e-03
## ASV6794      1.243366e-02  1.284102e-02  1.310133e-02  1.351576e-02
## ASV8324     -1.619462e-02 -1.674777e-02 -1.721519e-02 -1.779418e-02
## ASV8981      2.364035e-04  2.803625e-04  3.375010e-04  3.885556e-04
## ASV9859      8.214033e-03  8.647214e-03  9.131553e-03  9.612500e-03
## ASV0936      1.800430e-02  1.873855e-02  1.941033e-02  2.019047e-02
## ASV12683    -1.661236e-04 -1.765792e-04 -2.094692e-04 -2.226930e-04
## ASV1293      1.049818e-02  1.085930e-02  1.113486e-02  1.150790e-02
## ASV13055     2.157363e-04  2.488564e-04  2.675011e-04  3.035206e-04
## ASV17063    -8.384334e-03 -8.670317e-03 -8.935644e-03 -9.234662e-03
## ASV2228      6.832511e-03  7.065370e-03  7.287828e-03  7.531418e-03
## ASV2769      1.721247e-03  1.812256e-03  1.882568e-03  1.979520e-03
## ASV2803      6.797326e-03  7.003806e-03  7.107914e-03  7.314442e-03
## ASV2896      7.122502e-03  7.438975e-03  7.749563e-03  8.093070e-03
## ASV3062      9.468577e-03  9.918269e-03  1.035767e-02  1.084487e-02
## ASV3107      1.282959e-02  1.337124e-02  1.388147e-02  1.446205e-02
## ASV3265      1.489272e-02  1.539798e-02  1.578549e-02  1.630565e-02
## ASV3666      4.759918e-05  4.282259e-05  3.331818e-06 -4.950790e-06
## ASV4497      5.320660e-03  5.512309e-03  5.650458e-03  5.849393e-03
## ASV6914     -1.199162e-03 -1.262566e-03 -1.350414e-03 -1.420499e-03
## ASV0576     -1.605214e-02 -1.651765e-02 -1.677822e-02 -1.724503e-02
## ASV0673      2.089783e-02  2.166894e-02  2.231712e-02  2.312310e-02
## ASV0772      9.992190e-03  1.037950e-02  1.071988e-02  1.112976e-02
## ASV0862      2.590917e-03  2.765116e-03  2.962592e-03  3.154491e-03
## ASV0898      8.775405e-03  9.158647e-03  9.524156e-03  9.933443e-03
## ASV0910      9.730582e-03  1.014485e-02  1.054491e-02  1.098952e-02
## ASV0964     -6.258629e-03 -6.448087e-03 -6.573058e-03 -6.766363e-03
## ASV10059     7.526864e-03  7.874779e-03  8.224740e-03  8.602575e-03
## ASV10263    -1.282845e-02 -1.326936e-02 -1.360582e-02 -1.405668e-02
## ASV1088      1.708690e-02  1.781128e-02  1.850589e-02  1.928470e-02
## ASV1101      1.819466e-02  1.881400e-02  1.928340e-02  1.992094e-02
## ASV1183      5.404361e-03  5.621548e-03  5.821764e-03  6.051942e-03
## ASV11956     4.164082e-03  4.285620e-03  4.344391e-03  4.467358e-03
## ASV12774    -2.462744e-04 -2.816531e-04 -3.411529e-04 -3.821591e-04
## ASV1321      2.561645e-02  2.672627e-02  2.782054e-02  2.901492e-02
## ASV13793    -8.840326e-03 -9.143861e-03 -9.381789e-03 -9.692823e-03
## ASV14482     4.526368e-04  4.661990e-04  4.781378e-04  4.941653e-04
## ASV15483     4.206535e-03  4.381007e-03  4.537546e-03  4.723306e-03
## ASV2062      1.796189e-02  1.863953e-02  1.924336e-02  1.995760e-02
## ASV2132      1.591131e-02  1.656935e-02  1.717025e-02  1.787064e-02
## ASV2413      1.337883e-02  1.385984e-02  1.428030e-02  1.478497e-02
## ASV2490      3.847153e-02  3.971635e-02  4.062914e-02  4.190459e-02
## ASV2594      5.770000e-03  6.014646e-03  6.269025e-03  6.535378e-03
## ASV2822     -2.337922e-02 -2.418513e-02 -2.475262e-02 -2.557368e-02
## ASV2863      2.445917e-02  2.529616e-02  2.599239e-02  2.686091e-02
## ASV2910      9.094648e-03  9.410775e-03  9.652534e-03  9.980326e-03
## ASV2980      1.078221e-02  1.118842e-02  1.152490e-02  1.194874e-02
## ASV3307      1.857466e-02  1.921367e-02  1.969874e-02  2.035292e-02
## ASV3474      1.502879e-02  1.569540e-02  1.636572e-02  1.708557e-02
## ASV3502      1.421986e-02  1.478439e-02  1.529806e-02  1.589759e-02
## ASV4236      1.764765e-02  1.819081e-02  1.866541e-02  1.922413e-02
## ASV4842     -2.289731e-03 -2.372600e-03 -2.365212e-03 -2.440499e-03
## ASV4894     -8.860693e-03 -9.166299e-03 -9.382180e-03 -9.693896e-03
## ASV5290      7.974044e-03  8.298090e-03  8.584640e-03  8.928268e-03
## ASV5501      4.859722e-03  5.065100e-03  5.307198e-03  5.534169e-03
## ASV5795      5.415861e-03  5.639113e-03  5.862432e-03  6.101998e-03
## ASV5987     -2.477451e-02 -2.563068e-02 -2.620383e-02 -2.707467e-02
## ASV6267     -2.789552e-02 -2.885873e-02 -2.952849e-02 -3.050991e-02
## ASV6862      1.074099e-02  1.109599e-02  1.137716e-02  1.174498e-02
## ASV7145      4.643443e-03  4.798795e-03  4.985281e-03  5.154770e-03
## ASV7673     -8.861772e-03 -9.167699e-03 -9.382725e-03 -9.694404e-03
## ASV7789      6.192831e-03  6.506903e-03  6.871138e-03  7.220169e-03
## ASV7809      9.318308e-04  9.962712e-04  1.086677e-03  1.161276e-03
## ASV8002     -1.119720e-02 -1.158434e-02 -1.185093e-02 -1.224427e-02
## ASV8205      5.299694e-03  5.517261e-03  5.719439e-03  5.952783e-03
## ASV9155     -2.660879e-03 -2.742909e-03 -2.781893e-03 -2.861509e-03
## ASV9221      2.340655e-03  2.486840e-03  2.670832e-03  2.838199e-03
## ASV9311     -1.796384e-02 -1.858550e-02 -1.901425e-02 -1.964384e-02
## ASV9557     -1.226796e-02 -1.269214e-02 -1.299605e-02 -1.342608e-02
## ASV9936     -2.472193e-02 -2.557600e-02 -2.621092e-02 -2.707753e-02
## ASV1445      1.693455e-02  1.762184e-02  1.826809e-02  1.900097e-02
## ASV4232      7.364704e-03  7.719402e-03  8.106524e-03  8.498886e-03
## ASV6479      3.708568e-03  3.929927e-03  4.205556e-03  4.458471e-03
## ASV0142     -1.050724e-02 -1.086562e-02 -1.116097e-02 -1.153340e-02
## ASV0378      6.134127e-03  6.414191e-03  6.672874e-03  6.972242e-03
## ASV1122      1.671472e-02  1.741016e-02  1.808351e-02  1.882934e-02
## ASV0123     -9.224341e-03 -9.535951e-03 -9.797713e-03 -1.012159e-02
## ASV2064      4.050554e-03  4.147375e-03  4.205224e-03  4.299537e-03
## ASV4459     -4.624729e-04 -4.717406e-04 -4.473748e-04 -4.515438e-04
## ASV0448      4.923397e-03  5.149779e-03  5.359202e-03  5.601616e-03
## ASV0397      9.236235e-03  9.591633e-03  9.887584e-03  1.025940e-02
## ASV0485      1.039380e-02  1.077972e-02  1.110836e-02  1.151212e-02
## ASV1566      1.568635e-02  1.628388e-02  1.681501e-02  1.744557e-02
## ASV1365      1.376059e-02  1.429733e-02  1.478175e-02  1.534873e-02
## ASV1065      1.957259e-02  2.034582e-02  2.105949e-02  2.187827e-02
## ASV0722     -1.177151e-03 -1.233918e-03 -1.295550e-03 -1.360053e-03
## ASV12660    -9.930963e-03 -1.026477e-02 -1.050184e-02 -1.083976e-02
## ASV0223      2.925429e-03  3.037860e-03  3.134021e-03  3.251617e-03
## ASV0229      4.868472e-03  5.074972e-03  5.269232e-03  5.489375e-03
## ASV0877      1.278595e-03  1.287875e-03  1.226947e-03  1.225300e-03
## ASV0983      1.009795e-02  1.045912e-02  1.075938e-02  1.113458e-02
## ASV0626      2.179642e-03  2.310408e-03  2.427955e-03  2.571381e-03
## ASV4146      3.206005e-04  3.131279e-04  2.657284e-04  2.512078e-04
## ASV4175     -1.383857e-02 -1.440627e-02 -1.494789e-02 -1.554969e-02
## ASV2082     -8.575247e-03 -9.048886e-03 -9.560938e-03 -1.009096e-02
## ASV2272      6.571052e-03  6.843676e-03  7.111293e-03  7.405555e-03
## ASV2245     -1.001829e-02 -1.043507e-02 -1.083985e-02 -1.128230e-02
## ASV0590     -8.620467e-03 -9.110354e-03 -9.658983e-03 -1.020861e-02
## ASV0217      2.012950e-03  2.163564e-03  2.327123e-03  2.495022e-03
## ASV0416      5.400107e-03  5.523467e-03  5.583438e-03  5.698040e-03
## ASV1056      1.005707e-02  1.049129e-02  1.090027e-02  1.136599e-02
## ASV7777     -1.337066e-02 -1.392189e-02 -1.447184e-02 -1.505949e-02
## ASV0455      2.311438e-03  2.400244e-03  2.486246e-03  2.578636e-03
## ASV0604      6.835582e-03  7.140598e-03  7.419977e-03  7.748122e-03
## ASV6100     -9.557321e-03 -9.968641e-03 -1.038789e-02 -1.083033e-02
## ASV11359    -1.961020e-02 -2.039555e-02 -2.116173e-02 -2.199068e-02
## ASV6604      2.973697e-03  3.105061e-03  3.223398e-03  3.364709e-03
## ASV5004     -6.892336e-03 -7.168749e-03 -7.456708e-03 -7.750426e-03
## ASV1483     -2.889351e-03 -3.000101e-03 -3.119154e-03 -3.234128e-03
## ASV9773     -9.046457e-03 -9.423970e-03 -9.809544e-03 -1.021386e-02
## ASV4059      1.197087e-03  1.300964e-03  1.421386e-03  1.543211e-03
## ASV1193      1.035913e-02  1.076188e-02  1.111376e-02  1.153968e-02
## ASV4610     -2.068723e-04 -1.545212e-04 -9.191101e-05 -2.620834e-05
## ASV0742      2.869949e-04  3.557031e-04  4.176021e-04  4.969392e-04
## ASV1502     -1.305082e-03 -1.395271e-03 -1.518738e-03 -1.618682e-03
## ASV0195     -2.328637e-04 -2.640740e-04 -3.020903e-04 -3.398892e-04
## ASV1213      6.035848e-03  6.210515e-03  6.390385e-03  6.567541e-03
## ASV1648     -8.567201e-03 -8.936847e-03 -9.326233e-03 -9.724777e-03
## ASV6984     -8.056659e-03 -8.407014e-03 -8.790172e-03 -9.169784e-03
## ASV0396      6.716407e-05  8.812933e-05  1.170577e-04  1.389396e-04
## ASV4297      9.245031e-03  9.539479e-03  9.735902e-03  1.003679e-02
## ASV2622      1.532892e-02  1.587312e-02  1.633145e-02  1.689998e-02
## ASV3512      8.372379e-03  8.804168e-03  9.254087e-03  9.732447e-03
## ASV2411      1.253433e-02  1.308852e-02  1.365808e-02  1.425541e-02
## ASV2291     -7.658265e-03 -8.095573e-03 -8.512209e-03 -8.998462e-03
## ASV0807      1.520870e-02  1.579207e-02  1.628845e-02  1.689881e-02
## ASV1292      2.819738e-03  2.889622e-03  2.954434e-03  3.022180e-03
## ASV1035      1.282195e-02  1.327101e-02  1.368728e-02  1.415526e-02
## ASV0070      7.146009e-04  7.727571e-04  8.477606e-04  9.139605e-04
## ASV0255      9.587470e-04  9.742329e-04  9.790138e-04  9.896886e-04
## ASV0057     -3.167354e-03 -3.256646e-03 -3.318638e-03 -3.408083e-03
## ASV0077     -4.652460e-04 -4.669181e-04 -4.572430e-04 -4.574880e-04
## ASV0625      7.110154e-03  7.341043e-03  7.540072e-03  7.777840e-03
## ASV2464      4.833377e-02  4.992575e-02  5.133146e-02  5.296261e-02
## ASV1315      1.654676e-02  1.728760e-02  1.802493e-02  1.882631e-02
## ASV2673      1.426357e-02  1.490620e-02  1.553679e-02  1.623105e-02
## ASV2161      6.018699e-03  6.291711e-03  6.561682e-03  6.859197e-03
## ASV0337     -3.201139e-03 -3.334150e-03 -3.451232e-03 -3.593609e-03
## ASV7680     -2.113266e-02 -2.202344e-02 -2.293462e-02 -2.388851e-02
## ASV0611      1.190074e-02  1.240943e-02  1.289578e-02  1.344261e-02
## ASV3118     -1.322547e-02 -1.382641e-02 -1.445974e-02 -1.510766e-02
## ASV1284      2.670466e-04  8.226360e-05 -1.592979e-04 -3.887270e-04
## ASV0889      7.998006e-03  8.296209e-03  8.553831e-03  8.869760e-03
## ASV4649     -4.300022e-03 -4.473971e-03 -4.651917e-03 -4.837063e-03
## ASV1108     -1.033318e-02 -1.082485e-02 -1.135393e-02 -1.188940e-02
## ASV0738      6.597981e-03  6.950637e-03  7.349860e-03  7.740264e-03
## ASV0473     -1.568075e-03 -1.653279e-03 -1.717572e-03 -1.809195e-03
## ASV0598     -3.732238e-03 -3.946823e-03 -4.167435e-03 -4.405683e-03
## ASV0429      5.529016e-03  5.708678e-03  5.848036e-03  6.032279e-03
## ASV1549      1.321795e-02  1.381574e-02  1.442090e-02  1.506824e-02
## ASV1203      8.704202e-03  9.022984e-03  9.327683e-03  9.662220e-03
## ASV4532      1.855547e-04  1.864799e-04  1.791973e-04  1.809914e-04
## ASV0274      1.963387e-03  2.054686e-03  2.144795e-03  2.241334e-03
## ASV0163     -6.165542e-03 -6.369325e-03 -6.555556e-03 -6.768775e-03
## ASV1298      5.485358e-04  5.669446e-04  6.134740e-04  6.362164e-04
## ASV9424     -1.672593e-02 -1.745311e-02 -1.821782e-02 -1.900450e-02
## ASV0412      1.488019e-02  1.541766e-02  1.589055e-02  1.645129e-02
## ASV0284      2.222957e-03  2.256158e-03  2.262600e-03  2.287615e-03
## ASV0620     -4.472626e-03 -4.707223e-03 -4.979101e-03 -5.237599e-03
## ASV0153     -1.760010e-02 -1.838988e-02 -1.913138e-02 -1.998186e-02
## ASV0498      5.730716e-03  5.961780e-03  6.185825e-03  6.429291e-03
## ASV0097      3.470851e-03  3.627989e-03  3.789300e-03  3.958991e-03
## ASV0104     -2.100645e-02 -2.179805e-02 -2.245675e-02 -2.328517e-02
## ASV1282      6.422187e-03  6.617872e-03  6.726427e-03  6.920461e-03
## ASV3883     -7.329743e-03 -7.682007e-03 -8.065353e-03 -8.447824e-03
## ASV0801      3.098927e-03  3.230479e-03  3.389128e-03  3.532184e-03
## ASV1611     -1.533722e-02 -1.601537e-02 -1.672105e-02 -1.745432e-02
## ASV0227     -3.707814e-03 -3.911168e-03 -4.127258e-03 -4.352701e-03
## ASV0833      4.889170e-03  5.088567e-03  5.279055e-03  5.492041e-03
## ASV0718      2.177774e-02  2.266945e-02  2.353761e-02  2.448878e-02
## ASV1139      1.217461e-03  1.190580e-03  1.133753e-03  1.092515e-03
## ASV0766     -3.659327e-03 -3.835335e-03 -4.035478e-03 -4.227175e-03
## ASV2091      1.493002e-02  1.541140e-02  1.577957e-02  1.627245e-02
## ASV1238     -1.720284e-02 -1.797043e-02 -1.882188e-02 -1.965989e-02
## ASV9193     -2.968159e-03 -3.162144e-03 -3.434518e-03 -3.656916e-03
## ASV0290      1.468274e-03  1.495663e-03  1.487377e-03  1.512780e-03
## ASV0231      5.813370e-03  6.018665e-03  6.205832e-03  6.418904e-03
## ASV0185      5.013585e-03  5.279832e-03  5.576384e-03  5.871187e-03
## ASV2330      5.974675e-03  6.155194e-03  6.278483e-03  6.462086e-03
## ASV3119     -4.443288e-03 -4.674632e-03 -4.931899e-03 -5.187163e-03
## ASV2368     -9.345460e-03 -9.785552e-03 -1.027773e-02 -1.076173e-02
## ASV0122     -3.743573e-03 -3.883948e-03 -3.994506e-03 -4.141807e-03
## ASV1044      1.107463e-02  1.156625e-02  1.205751e-02  1.258929e-02
## ASV0160     -3.522363e-03 -3.632272e-03 -3.719670e-03 -3.833106e-03
## ASV0326      1.132262e-03  1.176324e-03  1.205476e-03  1.250817e-03
## ASV1388      1.953761e-02  2.027026e-02  2.089646e-02  2.166448e-02
## ASV0792      1.354458e-02  1.400722e-02  1.442468e-02  1.490511e-02
## ASV0036     -5.265200e-03 -5.499244e-03 -5.715467e-03 -5.966391e-03
## ASV2125      1.423291e-02  1.477909e-02  1.526401e-02  1.583901e-02
## ASV1075     -2.531911e-04 -2.670538e-04 -2.901311e-04 -3.064887e-04
## ASV0390      8.836870e-03  9.245428e-03  9.684266e-03  1.013063e-02
## ASV3790     -1.157048e-02 -1.205785e-02 -1.255144e-02 -1.307455e-02
## ASV1535     -4.139993e-03 -4.350679e-03 -4.589840e-03 -4.821231e-03
## ASV0263      1.360879e-02  1.415432e-02  1.470458e-02  1.528608e-02
## ASV0675      2.182721e-02  2.277023e-02  2.371219e-02  2.472743e-02
## ASV3348      2.005290e-03  2.101476e-03  2.186237e-03  2.290054e-03
## ASV0058     -5.722532e-03 -5.934024e-03 -6.120247e-03 -6.342016e-03
## ASV4142      7.462501e-03  7.711539e-03  7.922558e-03  8.181255e-03
## ASV0059     -4.512251e-03 -4.674065e-03 -4.817460e-03 -4.986573e-03
## ASV0013     -8.624166e-03 -8.966106e-03 -9.279583e-03 -9.642075e-03
## ASV0033     -4.541943e-03 -4.742826e-03 -4.936638e-03 -5.152673e-03
## ASV4354     -5.207152e-03 -5.424530e-03 -5.647577e-03 -5.881098e-03
## ASV0022     -3.833559e-03 -4.003559e-03 -4.173064e-03 -4.356457e-03
## ASV0134     -4.003614e-03 -4.199374e-03 -4.406296e-03 -4.621787e-03
## ASV0415      7.900379e-04  8.309307e-04  8.823956e-04  9.269026e-04
## ASV10103    -2.065033e-02 -2.154373e-02 -2.250978e-02 -2.347520e-02
## ASV1613      1.280295e-02  1.323345e-02  1.359971e-02  1.404358e-02
## ASV0135     -1.470359e-03 -1.510983e-03 -1.540568e-03 -1.581291e-03
## ASV0469     -1.748226e-02 -1.813627e-02 -1.875719e-02 -1.944964e-02
## ASV0471      1.117666e-02  1.161860e-02  1.204756e-02  1.251886e-02
## ASV0451     -2.887235e-03 -3.051711e-03 -3.218806e-03 -3.400417e-03
## ASV0747      6.566123e-03  6.832768e-03  7.080208e-03  7.363306e-03
## ASV1314     -7.398834e-03 -7.744741e-03 -8.112042e-03 -8.490123e-03
## ASV0425     -2.022126e-02 -2.090089e-02 -2.148556e-02 -2.219122e-02
## ASV0559     -5.691431e-03 -5.927933e-03 -6.158934e-03 -6.415619e-03
## ASV0148     -5.244592e-04 -5.065687e-04 -4.621690e-04 -4.361554e-04
## ASV0129      2.765330e-03  2.949270e-03  3.172131e-03  3.380892e-03
## ASV1072      1.007394e-03  1.020534e-03  1.016020e-03  1.024746e-03
## ASV2390      9.597140e-03  9.870990e-03  1.004576e-02  1.031738e-02
## ASV0548      7.593169e-03  7.886115e-03  8.149991e-03  8.458991e-03
## ASV0168     -3.718343e-03 -3.854455e-03 -3.976360e-03 -4.119500e-03
## ASV0066     -4.244806e-03 -4.400098e-03 -4.533087e-03 -4.694908e-03
## ASV0468     -2.427114e-03 -2.527412e-03 -2.635415e-03 -2.743727e-03
## ASV0172     -8.831935e-04 -8.951668e-04 -8.930899e-04 -9.019131e-04
## ASV0236      1.513856e-03  1.659851e-03  1.846545e-03  2.015411e-03
## ASV0250      7.976814e-03  8.380150e-03  8.820134e-03  9.265157e-03
## ASV0338      3.265006e-03  3.402248e-03  3.535598e-03  3.681144e-03
## ASV0450     -9.607598e-04 -1.019230e-03 -1.080567e-03 -1.146081e-03
## ASV0377      5.276702e-03  5.469220e-03  5.644247e-03  5.845157e-03
## ASV1022     -1.124539e-04 -1.078262e-04 -9.104212e-05 -8.327788e-05
## ASV6174     -3.508479e-04 -3.771189e-04 -4.204155e-04 -4.507797e-04
## ASV0786     -1.451119e-03 -1.537981e-03 -1.632839e-03 -1.729107e-03
## ASV0053     -6.125953e-03 -6.372027e-03 -6.605349e-03 -6.866983e-03
## ASV0697     -3.344128e-03 -3.462875e-03 -3.568861e-03 -3.693823e-03
## ASV0785      7.344014e-03  7.615681e-03  7.862888e-03  8.148413e-03
## ASV1967     -7.220727e-03 -7.488310e-03 -7.726812e-03 -8.008067e-03
## ASV0385      2.939436e-03  3.069499e-03  3.195643e-03  3.334304e-03
## ASV0295      1.028177e-03  1.098065e-03  1.182131e-03  1.261588e-03
## ASV0072     -5.430632e-03 -5.615044e-03 -5.771658e-03 -5.961644e-03
## ASV0157      1.036484e-04  1.534245e-04  2.288012e-04  2.903939e-04
## ASV0501      1.332871e-02  1.386581e-02  1.440087e-02  1.497248e-02
## ASV10729    -1.718000e-02 -1.790002e-02 -1.863403e-02 -1.940692e-02
## ASV1470      6.766934e-03  6.957509e-03  7.098416e-03  7.288066e-03
## ASV0050     -1.351600e-02 -1.401803e-02 -1.447975e-02 -1.500695e-02
## ASV0411     -3.539694e-03 -3.698068e-03 -3.858172e-03 -4.030001e-03
## ASV0549      5.491296e-03  5.725912e-03  5.956697e-03  6.208573e-03
## ASV0184      1.693986e-03  1.762433e-03  1.835873e-03  1.909920e-03
## ASV0705      3.053762e-03  3.156054e-03  3.242525e-03  3.347101e-03
## ASV1715      7.250594e-03  7.540589e-03  7.827247e-03  8.136161e-03
## ASV0603      1.298094e-03  1.362098e-03  1.435630e-03  1.507059e-03
## ASV0826      1.183663e-02  1.229289e-02  1.272394e-02  1.320707e-02
## ASV0034     -3.553963e-03 -3.678025e-03 -3.793267e-03 -3.922536e-03
## ASV0838      5.708046e-04  4.778665e-04  3.588066e-04  2.387338e-04
## ASV0614     -3.229307e-03 -3.353220e-03 -3.469491e-03 -3.600422e-03
## ASV0014     -8.651608e-03 -8.986401e-03 -9.310612e-03 -9.665359e-03
## ASV0585     -4.668957e-04 -5.542833e-04 -6.575159e-04 -7.601435e-04
## ASV0016     -9.037459e-03 -9.387207e-03 -9.734975e-03 -1.010623e-02
## ASV5394     -7.062415e-03 -7.349477e-03 -7.626045e-03 -7.931307e-03
## ASV0666      1.346262e-02  1.392165e-02  1.436141e-02  1.483986e-02
## ASV2085      1.074079e-03  1.002761e-03  9.053973e-04  8.136423e-04
## ASV0003     -6.146604e-03 -6.383826e-03 -6.626556e-03 -6.878823e-03
## ASV0346      3.534279e-03  3.689887e-03  3.839746e-03  4.006125e-03
## ASV0267      4.415001e-04  4.797496e-04  5.190692e-04  5.616942e-04
## ASV0353      5.471627e-03  5.711288e-03  5.960561e-03  6.219484e-03
## ASV2419      1.292039e-02  1.340454e-02  1.388760e-02  1.439957e-02
## ASV0447      8.059020e-03  8.411855e-03  8.772340e-03  9.152784e-03
## ASV0654      1.073763e-02  1.115329e-02  1.155729e-02  1.199732e-02
## ASV0151      2.043261e-03  2.154247e-03  2.264429e-03  2.386701e-03
## ASV0065     -4.036234e-03 -4.187349e-03 -4.330523e-03 -4.489786e-03
## ASV0527      1.011145e-02  1.049999e-02  1.089213e-02  1.130472e-02
## ASV4055     -2.132854e-03 -2.247735e-03 -2.369558e-03 -2.498180e-03
## ASV0166     -4.649183e-03 -4.806639e-03 -4.971761e-03 -5.136929e-03
## ASV0417     -1.622608e-03 -1.662474e-03 -1.693873e-03 -1.732900e-03
## ASV0078     -2.791673e-03 -2.886150e-03 -2.974295e-03 -3.071833e-03
## ASV0322      5.045994e-05  9.063440e-05  1.482541e-04  1.992238e-04
## ASV0156     -7.723888e-03 -8.051953e-03 -8.390132e-03 -8.744242e-03
## ASV0648     -1.694139e-02 -1.766393e-02 -1.840988e-02 -1.918855e-02
## ASV0407     -1.391968e-03 -1.458204e-03 -1.530284e-03 -1.603109e-03
## ASV2030     -2.684422e-03 -2.802945e-03 -2.920294e-03 -3.050939e-03
## ASV0300      2.154694e-03  2.251799e-03  2.349881e-03  2.454712e-03
## ASV1150      6.039373e-04  6.355485e-04  6.666061e-04  7.009467e-04
## ASV0958      6.806707e-03  7.126273e-03  7.461543e-03  7.810771e-03
## ASV0216     -6.253212e-03 -6.497020e-03 -6.756927e-03 -7.019708e-03
## ASV0446      1.039050e-02  1.082829e-02  1.127431e-02  1.174398e-02
## ASV0367     -6.603842e-03 -6.874564e-03 -7.148032e-03 -7.438060e-03
## ASV0200     -3.892202e-03 -4.048847e-03 -4.200882e-03 -4.367471e-03
## ASV0334     -1.324210e-03 -1.345534e-03 -1.373354e-03 -1.393936e-03
## ASV1311      1.796346e-03  1.831364e-03  1.876010e-03  1.908963e-03
## ASV0458      2.599139e-03  2.650549e-03  2.682922e-03  2.730044e-03
## ASV1371      7.411006e-04  7.751312e-04  8.081147e-04  8.442312e-04
## ASV0418      7.530367e-03  7.783334e-03  8.046282e-03  8.310987e-03
## ASV0004      1.067514e-03  1.102034e-03  1.132186e-03  1.167745e-03
## ASV1943      1.646725e-02  1.682428e-02  1.686141e-02  1.719826e-02
## ASV1495     -3.122223e-03 -3.318483e-03 -3.524096e-03 -3.744366e-03
## ASV0901     -7.911274e-03 -8.263297e-03 -8.615362e-03 -8.996710e-03
## ASV0628      3.032838e-03  3.112408e-03  3.190012e-03  3.268820e-03
## ASV0400      2.067994e-03  2.134443e-03  2.197275e-03  2.264941e-03
## ASV0116     -2.302149e-03 -2.402992e-03 -2.505191e-03 -2.614208e-03
## ASV0788      2.051949e-02  2.142696e-02  2.236617e-02  2.335023e-02
## ASV0117      1.636869e-03  1.714070e-03  1.794835e-03  1.878953e-03
## ASV3137     -3.956516e-04 -4.088615e-04 -4.219689e-04 -4.354837e-04
## ASV0001      1.119103e-03  1.153614e-03  1.189410e-03  1.225107e-03
## ASV1651      3.313328e-03  3.423126e-03  3.532871e-03  3.647360e-03
## ASV1692      1.693334e-02  1.767171e-02  1.842692e-02  1.922469e-02
## ASV0660      4.169210e-03  4.261296e-03  4.350827e-03  4.437954e-03
## ASV0508      1.966033e-04  2.005132e-04  2.031388e-04  2.066823e-04
## ASV1660     -3.931937e-03 -4.122539e-03 -4.316119e-03 -4.523275e-03
## ASV0233      4.919859e-03  5.119736e-03  5.326441e-03  5.540628e-03
## ASV1343     -9.572067e-03 -9.987531e-03 -1.041361e-02 -1.086278e-02
## ASV0209      3.767849e-03  3.884925e-03  4.000705e-03  4.121178e-03
## ASV0193     -4.484975e-03 -4.627124e-03 -4.783013e-03 -4.930248e-03
## ASV0357      2.836006e-03  2.994931e-03  3.167442e-03  3.345235e-03
## ASV0198      3.742543e-03  3.883373e-03  4.026383e-03  4.176104e-03
## ASV0007      9.334919e-04  9.592418e-04  9.870033e-04  1.013208e-03
## ASV1772     -1.085542e-03 -1.086350e-03 -1.069298e-03 -1.060307e-03
## ASV0009      7.231348e-04  7.403052e-04  7.600107e-04  7.770808e-04
## ASV0006     -1.236548e-03 -1.294255e-03 -1.350772e-03 -1.413325e-03
## ASV0011     -3.876282e-03 -4.040284e-03 -4.209520e-03 -4.386098e-03
## ASV0015      5.406908e-04  5.529213e-04  5.627801e-04  5.745089e-04
## ASV0017      6.188138e-04  6.337668e-04  6.478309e-04  6.625579e-04
## ASV0235     -3.636642e-03 -3.792793e-03 -3.950923e-03 -4.119183e-03
## ASV0382      2.746720e-03  2.853830e-03  2.955071e-03  3.066725e-03
## ASV2357      1.167231e-02  1.216855e-02  1.268619e-02  1.322190e-02
## ASV0567     -2.381157e-03 -2.491197e-03 -2.607888e-03 -2.728737e-03
## ASV0165      1.924666e-03  2.004142e-03  2.085591e-03  2.170679e-03
## ASV0005      2.615557e-03  2.715369e-03  2.816251e-03  2.921915e-03
## ASV0384      1.554821e-04  1.852537e-04  2.205740e-04  2.563361e-04
## ASV0002      4.539706e-04  4.702104e-04  4.839416e-04  5.009354e-04
## ASV3017      1.241039e-02  1.281620e-02  1.321848e-02  1.363914e-02
## ASV0091     -3.587501e-04 -3.744832e-04 -3.890370e-04 -4.063402e-04
## ASV0186     -5.356581e-03 -5.564262e-03 -5.774279e-03 -5.994277e-03
## ASV0370      2.687571e-03  2.785591e-03  2.893227e-03  2.997087e-03
## ASV0018      3.387749e-03  3.519083e-03  3.654706e-03  3.794306e-03
## ASV1377      3.103107e-02  3.209820e-02  3.319316e-02  3.431040e-02
## ASV0019      3.566639e-03  3.705649e-03  3.853345e-03  4.001544e-03
## ASV0023     -2.424762e-03 -2.528844e-03 -2.628121e-03 -2.739531e-03
## ASV2194      4.095020e-03  4.283649e-03  4.480511e-03  4.686306e-03
## ASV1155      1.320152e-02  1.368157e-02  1.406372e-02  1.456721e-02
## ASV0510     -2.931436e-03 -3.007449e-03 -3.131268e-03 -3.211252e-03
## ASV2371     -7.893408e-03 -8.173844e-03 -8.411403e-03 -8.704529e-03
## ASV0024     -2.993243e-03 -3.120676e-03 -3.247501e-03 -3.384252e-03
## ASV2452      6.944456e-03  7.133187e-03  7.339282e-03  7.529792e-03
## ASV2332     -2.337503e-02 -2.424615e-02 -2.505860e-02 -2.598090e-02
## ASV2591      8.299139e-03  8.695124e-03  9.144477e-03  9.572382e-03
## ASV0521      6.089166e-03  6.350876e-03  6.621113e-03  6.903507e-03
## ASV5542      5.732983e-03  5.970988e-03  6.247354e-03  6.503545e-03
## ASV0336     -1.179436e-03 -1.249145e-03 -1.322993e-03 -1.400437e-03
## ASV10102     1.063332e-02  1.107836e-02  1.155028e-02  1.202830e-02
## ASV16823    -1.320086e-02 -1.362675e-02 -1.398246e-02 -1.442471e-02
## ASV3104      6.825865e-02  7.045950e-02  7.234672e-02  7.463621e-02
## ASV0781      1.109427e-02  1.152998e-02  1.198993e-02  1.245584e-02
## ASV10899     8.885110e-03  9.348542e-03  9.853183e-03  1.036381e-02
## ASV11222    -2.321742e-02 -2.396629e-02 -2.460997e-02 -2.538918e-02
## ASV11327    -2.083128e-02 -2.150278e-02 -2.209509e-02 -2.279487e-02
## ASV12458    -2.318656e-02 -2.393353e-02 -2.460931e-02 -2.538889e-02
## ASV1636      1.422861e-02  1.473651e-02  1.527723e-02  1.581204e-02
## ASV1890     -9.549578e-03 -9.807164e-03 -1.000664e-02 -1.027071e-02
## ASV2898      1.915916e-02  1.984631e-02  2.055992e-02  2.128525e-02
## ASV8328      6.098859e-03  6.514830e-03  6.989212e-03  7.457172e-03
## ASV0709     -2.214156e-02 -2.296808e-02 -2.385644e-02 -2.473203e-02
## ASV0856      2.131200e-02  2.225639e-02  2.325025e-02  2.427103e-02
## ASV0909      8.496500e-03  8.975966e-03  9.466323e-03  9.997368e-03
## ASV0937     -1.459952e-02 -1.524216e-02 -1.588618e-02 -1.658351e-02
## ASV11390    -3.308258e-02 -3.414849e-02 -3.512211e-02 -3.623525e-02
## ASV11966     1.097094e-02  1.147535e-02  1.200988e-02  1.255577e-02
## ASV12990     6.065303e-03  6.270058e-03  6.511013e-03  6.725491e-03
## ASV14797     8.800565e-03  9.091800e-03  9.409844e-03  9.714865e-03
## ASV14904    -4.747151e-02 -4.900132e-02 -5.039886e-02 -5.199641e-02
## ASV15304     7.494899e-03  7.862107e-03  8.267538e-03  8.667741e-03
## ASV16696    -1.639691e-02 -1.692530e-02 -1.741378e-02 -1.796565e-02
## ASV1690      3.596780e-02  3.752273e-02  3.910488e-02  4.076953e-02
## ASV2029      2.172875e-02  2.254880e-02  2.341365e-02  2.428610e-02
## ASV2834      2.940534e-02  3.061075e-02  3.186709e-02  3.315896e-02
## ASV4003      2.806781e-02  2.943195e-02  3.088991e-02  3.238797e-02
## ASV4064      1.421099e-02  1.480505e-02  1.543694e-02  1.607538e-02
## ASV4294      1.058635e-02  1.112663e-02  1.170892e-02  1.230333e-02
## ASV4609      7.246936e-03  7.518802e-03  7.905116e-03  8.198645e-03
## ASV6283     -1.534406e-02 -1.583965e-02 -1.627820e-02 -1.679392e-02
## ASV6491     -2.197817e-02 -2.268760e-02 -2.333185e-02 -2.407080e-02
## ASV7453      1.475893e-02  1.544619e-02  1.621564e-02  1.696418e-02
## ASV7959      6.652610e-03  7.019239e-03  7.442102e-03  7.849102e-03
## ASV8219      1.899413e-01  1.960762e-01  2.016406e-01  2.080230e-01
## ASV8547     -1.966433e-02 -2.029909e-02 -2.088964e-02 -2.155057e-02
## ASV9319      1.112464e-02  1.162010e-02  1.215698e-02  1.269557e-02
## ASV9382     -3.846772e-02 -3.970958e-02 -4.087391e-02 -4.216650e-02
## ASV11516    -2.567626e-02 -2.650466e-02 -2.730079e-02 -2.816377e-02
## ASV14377    -1.852731e-02 -1.912471e-02 -1.971286e-02 -2.033571e-02
## ASV1867      1.787810e-02  1.863587e-02  1.943667e-02  2.025399e-02
## ASV1895      6.680825e-03  6.849976e-03  7.035043e-03  7.202571e-03
## ASV3168      9.173534e-03  9.460526e-03  9.769810e-03  1.006663e-02
## ASV4449      5.854245e-02  6.088572e-02  6.328466e-02  6.579648e-02
## ASV6596      1.514649e-02  1.589653e-02  1.669087e-02  1.751515e-02
## ASV7492      3.684613e-04  5.006490e-04  6.475411e-04  8.029424e-04
## ASV9854     -3.846265e-03 -3.966919e-03 -4.071148e-03 -4.195817e-03
## ASV6296      3.107100e-01  3.207264e-01  3.308048e-01  3.412462e-01
## ASV4201      4.631151e-03  4.954351e-03  5.296239e-03  5.661155e-03
## ASV0552      1.219345e-02  1.269929e-02  1.322429e-02  1.376683e-02
## ASV3671     -7.715254e-03 -8.035093e-03 -8.356586e-03 -8.703101e-03
## ASV3529     -1.066517e-04 -3.379473e-05  3.578915e-05  1.204115e-04
## ASV1060      3.601499e-03  3.773078e-03  3.949561e-03  4.137717e-03
## ASV0239     -3.379851e-03 -3.476467e-03 -3.571429e-03 -3.669836e-03
## ASV5711     -1.794650e-02 -1.861787e-02 -1.930860e-02 -2.002165e-02
## ASV4152     -2.732502e-02 -2.843216e-02 -2.956491e-02 -3.074921e-02
## ASV1461      1.110397e-02  1.142891e-02  1.178800e-02  1.212254e-02
## ASV2877      5.935215e-03  6.115272e-03  6.304785e-03  6.489894e-03
## ASV0012      1.221229e-03  1.270254e-03  1.319512e-03  1.371935e-03
## ASV9823      6.823818e-04  6.523018e-04  6.240809e-04  5.831601e-04
## ASV0008      1.281160e-03  1.331724e-03  1.384284e-03  1.438400e-03
## ASV7832     -1.649921e-02 -1.719458e-02 -1.792111e-02 -1.867055e-02
## ASV1915     -1.918167e-03 -1.997513e-03 -2.085949e-03 -2.172914e-03
## ASV0055     -1.825180e-03 -1.918894e-03 -2.017564e-03 -2.120813e-03
## ASV0032      3.996720e-04  4.043248e-04  4.126683e-04  4.166224e-04
## ASV2977     -2.239862e-02 -2.329131e-02 -2.422281e-02 -2.517680e-02
## ASV0466      1.474733e-02  1.517944e-02  1.565501e-02  1.609867e-02
## ASV3866      1.330502e-02  1.388830e-02  1.449855e-02  1.513091e-02
## ASV0040      4.568241e-03  4.756339e-03  4.954200e-03  5.156334e-03
## ASV0496     -2.408202e-03 -2.569084e-03 -2.732209e-03 -2.912323e-03
## ASV0052      3.847113e-03  4.006098e-03  4.176996e-03  4.348242e-03
## ASV3828     -1.090246e-02 -1.124834e-02 -1.163115e-02 -1.199262e-02
## ASV1930      5.894465e-03  6.087243e-03  6.281971e-03  6.481366e-03
## ASV2126      1.088226e-02  1.129499e-02  1.173267e-02  1.217272e-02
## ASV0793      1.480682e-02  1.543813e-02  1.609452e-02  1.677493e-02
## ASV0299     -4.540037e-04 -4.878474e-04 -5.273448e-04 -5.676567e-04
## ASV0208      1.036912e-02  1.080020e-02  1.125386e-02  1.171848e-02
## ASV0511     -3.240414e-03 -3.328194e-03 -3.430194e-03 -3.520421e-03
## ASV1123     -1.026721e-02 -1.057395e-02 -1.091465e-02 -1.123178e-02
## ASV0099      5.878188e-04  6.237942e-04  6.613585e-04  7.019818e-04
## ASV0752     -8.093875e-03 -8.461542e-03 -8.844644e-03 -9.244106e-03
## ASV0883      1.093144e-02  1.141665e-02  1.192310e-02  1.244770e-02
## ASV0683      1.397624e-02  1.458782e-02  1.521512e-02  1.587584e-02
## ASV4117     -2.118087e-02 -2.207092e-02 -2.299792e-02 -2.395785e-02
## ASV2172      7.067843e-04  7.025501e-04  7.008455e-04  6.916369e-04
## ASV0330     -4.036323e-03 -4.208780e-03 -4.388881e-03 -4.575248e-03
## ASV0728      1.862955e-02  1.935455e-02  2.012413e-02  2.089781e-02
## ASV0499      5.519782e-03  5.765944e-03  6.021102e-03  6.287930e-03
## ASV0120     -8.300558e-03 -8.623476e-03 -8.964387e-03 -9.308133e-03
## ASV1446      4.089519e-03  4.140182e-03  4.192423e-03  4.231140e-03
## ASV17171    -1.625727e-02 -1.692107e-02 -1.762411e-02 -1.833935e-02
## ASV0533      1.485197e-03  1.557906e-03  1.629889e-03  1.709115e-03
## ASV2495     -5.461981e-03 -5.758056e-03 -6.059217e-03 -6.386379e-03
## ASV5582      5.366417e-03  5.480942e-03  5.618124e-03  5.729052e-03
## ASV1488      2.468099e-03  2.543177e-03  2.634414e-03  2.711727e-03
## ASV0682      4.069195e-03  4.251762e-03  4.441261e-03  4.639072e-03
## ASV0068     -6.373821e-03 -6.625452e-03 -6.889864e-03 -7.157913e-03
## ASV1987     -1.799630e-02 -1.881847e-02 -1.967504e-02 -2.056814e-02
## ASV0035     -2.155228e-03 -2.295720e-03 -2.441567e-03 -2.600765e-03
## ASV7192     -9.204047e-03 -9.540904e-03 -9.898581e-03 -1.025496e-02
## ASV0873     -1.494698e-02 -1.613102e-02 -1.731816e-02 -1.864684e-02
## ASV4749     -3.058839e-03 -3.315599e-03 -3.568402e-03 -3.860186e-03
## ASV2174      5.078250e-03  5.194298e-03  5.326222e-03  5.439233e-03
## ASV1476     -7.909009e-03 -8.273780e-03 -8.652063e-03 -9.049540e-03
## ASV0740     -2.204257e-02 -2.303222e-02 -2.406110e-02 -2.513592e-02
## ASV0170     -3.965155e-03 -4.127173e-03 -4.297334e-03 -4.471388e-03
## ASV2466     -1.824309e-02 -1.900183e-02 -1.980005e-02 -2.061757e-02
## ASV1709      6.184739e-03  6.435259e-03  6.711975e-03  6.985875e-03
## ASV6170     -2.982730e-02 -3.111940e-02 -3.246558e-02 -3.386199e-02
## ASV3673      1.508077e-02  1.575341e-02  1.645326e-02  1.718244e-02
## ASV1745     -4.325429e-03 -4.537210e-03 -4.753429e-03 -4.985367e-03
##                                                                    
## (Intercept)  1.107001e-01  1.149587e-01  1.193465e-01  1.238652e-01
## ASV1236      1.944708e-02  2.010898e-02  2.078675e-02  2.148047e-02
## ASV0421      4.056658e-03  4.277420e-03  4.508708e-03  4.750829e-03
## ASV0691     -1.174613e-02 -1.200371e-02 -1.225927e-02 -1.251246e-02
## ASV0899      1.675115e-02  1.729977e-02  1.785891e-02  1.842840e-02
## ASV1004      3.904003e-02  4.035700e-02  4.170358e-02  4.307974e-02
## ASV1041     -1.532253e-02 -1.578404e-02 -1.625019e-02 -1.672039e-02
## ASV1058      2.436587e-02  2.519415e-02  2.604205e-02  2.690968e-02
## ASV12542     8.793502e-03  9.067538e-03  9.346954e-03  9.631788e-03
## ASV1294      2.280437e-02  2.358701e-02  2.438896e-02  2.521040e-02
## ASV13113     1.020055e-02  1.068108e-02  1.118335e-02  1.170822e-02
## ASV1318      2.257978e-02  2.334233e-02  2.412240e-02  2.492002e-02
## ASV2269     -3.836815e-02 -3.961164e-02 -4.087844e-02 -4.216805e-02
## ASV2542      2.300082e-02  2.397757e-02  2.499205e-02  2.604549e-02
## ASV2660     -1.507376e-02 -1.555804e-02 -1.605158e-02 -1.655425e-02
## ASV2737      4.611763e-03  4.740495e-03  4.871082e-03  5.003542e-03
## ASV2840      1.828283e-02  1.877992e-02  1.927972e-02  1.978168e-02
## ASV3053      1.000693e-01  1.032148e-01  1.064212e-01  1.096881e-01
## ASV3077      6.522740e-03  6.736883e-03  6.956012e-03  7.180198e-03
## ASV3134      1.554573e-02  1.625020e-02  1.698499e-02  1.775128e-02
## ASV3140      1.838639e-02  1.909745e-02  1.983061e-02  2.058620e-02
## ASV3579      8.389595e-03  8.800242e-03  9.229584e-03  9.678283e-03
## ASV6119     -1.049851e-02 -1.083849e-02 -1.118481e-02 -1.153734e-02
## ASV7557     -2.133448e-02 -2.202528e-02 -2.272898e-02 -2.344526e-02
## ASV8422      5.147483e-03  5.314474e-03  5.485324e-03  5.660106e-03
## ASV1086     -6.323353e-04 -6.482925e-04 -6.646486e-04 -6.814576e-04
## ASV1310      1.031824e-02  1.065981e-02  1.100847e-02  1.136415e-02
## ASV15750    -1.087306e-03 -1.106550e-03 -1.124868e-03 -1.142146e-03
## ASV16905    -4.386627e-03 -4.528637e-03 -4.673296e-03 -4.820542e-03
## ASV2033      2.348632e-02  2.448275e-02  2.551593e-02  2.658678e-02
## ASV2089      9.271320e-03  9.571948e-03  9.878176e-03  1.018986e-02
## ASV2127      3.052422e-02  3.155221e-02  3.260373e-02  3.367881e-02
## ASV2725      2.315829e-02  2.388015e-02  2.461445e-02  2.536094e-02
## ASV2804     -9.080606e-03 -9.374565e-03 -9.674012e-03 -9.978817e-03
## ASV3075      2.280340e-02  2.371885e-02  2.466801e-02  2.565202e-02
## ASV3327      3.319318e-02  3.455482e-02  3.596440e-02  3.742308e-02
## ASV3342      2.811928e-02  2.926384e-02  3.044905e-02  3.167599e-02
## ASV3532     -3.013508e-02 -3.133554e-02 -3.257843e-02 -3.386502e-02
## ASV3600      1.412978e-02  1.469322e-02  1.527585e-02  1.587812e-02
## ASV4013      2.432347e-02  2.519830e-02  2.609626e-02  2.701747e-02
## ASV4136      2.377597e-02  2.455381e-02  2.534873e-02  2.616078e-02
## ASV4195      9.269663e-02  9.569757e-02  9.875460e-02  1.018664e-01
## ASV4407     -3.581630e-02 -3.697583e-02 -3.815706e-02 -3.935946e-02
## ASV4717      5.170278e-03  5.303798e-03  5.438700e-03  5.575027e-03
## ASV6794      1.394234e-02  1.437793e-02  1.482262e-02  1.527655e-02
## ASV8324     -1.837783e-02 -1.897286e-02 -1.957903e-02 -2.019609e-02
## ASV8981      4.453500e-04  5.068552e-04  5.733516e-04  6.451213e-04
## ASV9859      1.012026e-02  1.065486e-02  1.121764e-02  1.181000e-02
## ASV0936      2.099363e-02  2.182272e-02  2.267809e-02  2.356009e-02
## ASV12683    -2.348588e-04 -2.472489e-04 -2.597628e-04 -2.723246e-04
## ASV1293      1.188824e-02  1.227653e-02  1.267268e-02  1.307661e-02
## ASV13055     3.442425e-04  3.881801e-04  4.355635e-04  4.865864e-04
## ASV17063    -9.537540e-03 -9.846423e-03 -1.016110e-02 -1.048145e-02
## ASV2228      7.778433e-03  8.030360e-03  8.287018e-03  8.548300e-03
## ASV2769      2.081492e-03  2.187843e-03  2.298741e-03  2.414281e-03
## ASV2803      7.524655e-03  7.737477e-03  7.952901e-03  8.170860e-03
## ASV2896      8.451551e-03  8.825479e-03  9.215544e-03  9.622435e-03
## ASV3062      1.135394e-02  1.188480e-02  1.243828e-02  1.301509e-02
## ASV3107      1.506458e-02  1.568966e-02  1.633803e-02  1.701040e-02
## ASV3265      1.683645e-02  1.737774e-02  1.792938e-02  1.849123e-02
## ASV3666     -1.383951e-05 -2.376674e-05 -3.470745e-05 -4.671360e-05
## ASV4497      6.053208e-03  6.261993e-03  6.475860e-03  6.694842e-03
## ASV6914     -1.494201e-03 -1.571465e-03 -1.652302e-03 -1.736813e-03
## ASV0576     -1.771506e-02 -1.818874e-02 -1.866579e-02 -1.914584e-02
## ASV0673      2.395098e-02  2.480080e-02  2.567278e-02  2.656714e-02
## ASV0772      1.155266e-02  1.198887e-02  1.243881e-02  1.290279e-02
## ASV0862      3.357721e-03  3.571895e-03  3.797180e-03  4.033868e-03
## ASV0898      1.035849e-02  1.079922e-02  1.125591e-02  1.172892e-02
## ASV0910      1.145088e-02  1.192951e-02  1.242594e-02  1.294068e-02
## ASV0964     -6.960675e-03 -7.156898e-03 -7.355107e-03 -7.555186e-03
## ASV10059     8.996277e-03  9.406588e-03  9.834143e-03  1.027952e-02
## ASV10263    -1.451783e-02 -1.498835e-02 -1.546773e-02 -1.595580e-02
## ASV1088      2.009422e-02  2.093526e-02  2.180892e-02  2.271632e-02
## ASV1101      2.057106e-02  2.123389e-02  2.190930e-02  2.259712e-02
## ASV1183      6.290320e-03  6.536851e-03  6.791653e-03  7.054935e-03
## ASV11956     4.591375e-03  4.716826e-03  4.843837e-03  4.972414e-03
## ASV12774    -4.270711e-04 -4.754047e-04 -5.271814e-04 -5.825447e-04
## ASV1321      3.025477e-02  3.154148e-02  3.287652e-02  3.426116e-02
## ASV13793    -1.001085e-02 -1.033536e-02 -1.066600e-02 -1.100263e-02
## ASV14482     5.103638e-04  5.271762e-04  5.447997e-04  5.633106e-04
## ASV15483     4.915436e-03  5.114059e-03  5.319397e-03  5.531591e-03
## ASV2062      2.069257e-02  2.144899e-02  2.222722e-02  2.302762e-02
## ASV2132      1.859509e-02  1.934439e-02  2.011915e-02  2.091990e-02
## ASV2413      1.530250e-02  1.583351e-02  1.637822e-02  1.693681e-02
## ASV2490      4.320094e-02  4.451928e-02  4.585914e-02  4.722008e-02
## ASV2594      6.812058e-03  7.099932e-03  7.399531e-03  7.711332e-03
## ASV2822     -2.641288e-02 -2.726920e-02 -2.814169e-02 -2.903001e-02
## ASV2863      2.774815e-02  2.865527e-02  2.958200e-02  3.052837e-02
## ASV2910      1.031509e-02  1.065734e-02  1.100717e-02  1.136460e-02
## ASV2980      1.238491e-02  1.283344e-02  1.329424e-02  1.376746e-02
## ASV3307      2.102085e-02  2.170243e-02  2.239686e-02  2.310389e-02
## ASV3474      1.783407e-02  1.861197e-02  1.942027e-02  2.025984e-02
## ASV3502      1.651677e-02  1.715635e-02  1.781687e-02  1.849885e-02
## ASV4236      1.978888e-02  2.036051e-02  2.093881e-02  2.152342e-02
## ASV4842     -2.517229e-03 -2.594493e-03 -2.671742e-03 -2.748735e-03
## ASV4894     -1.001206e-02 -1.033671e-02 -1.066749e-02 -1.100427e-02
## ASV5290      9.283304e-03  9.650049e-03  1.002881e-02  1.041983e-02
## ASV5501      5.770243e-03  6.016191e-03  6.272647e-03  6.540100e-03
## ASV5795      6.349544e-03  6.605479e-03  6.870081e-03  7.143527e-03
## ASV5987     -2.796335e-02 -2.887016e-02 -2.979408e-02 -3.073476e-02
## ASV6267     -3.151138e-02 -3.253327e-02 -3.357443e-02 -3.463449e-02
## ASV6862      1.211974e-02  1.250206e-02  1.289198e-02  1.328952e-02
## ASV7145      5.328021e-03  5.506087e-03  5.689315e-03  5.877892e-03
## ASV7673     -1.001264e-02 -1.033736e-02 -1.066821e-02 -1.100506e-02
## ASV7789      7.586227e-03  7.970060e-03  8.372541e-03  8.794444e-03
## ASV7809      1.239904e-03  1.322918e-03  1.410595e-03  1.503107e-03
## ASV8002     -1.264626e-02 -1.305642e-02 -1.347432e-02 -1.389981e-02
## ASV8205      6.193989e-03  6.443668e-03  6.702140e-03  6.969636e-03
## ASV9155     -2.942225e-03 -3.023585e-03 -3.105356e-03 -3.187428e-03
## ASV9221      3.014810e-03  3.201590e-03  3.399155e-03  3.608008e-03
## ASV9311     -2.028889e-02 -2.094701e-02 -2.161756e-02 -2.230032e-02
## ASV9557     -1.386699e-02 -1.431682e-02 -1.477515e-02 -1.524183e-02
## ASV9936     -2.796681e-02 -2.887407e-02 -2.979848e-02 -3.073976e-02
## ASV1445      1.975807e-02  2.054053e-02  2.134895e-02  2.218388e-02
## ASV4232      8.909965e-03  9.341104e-03  9.793318e-03  1.026763e-02
## ASV6479      4.724408e-03  5.005491e-03  5.302563e-03  5.616395e-03
## ASV0142     -1.191312e-02 -1.230092e-02 -1.269683e-02 -1.310080e-02
## ASV0378      7.284277e-03  7.608634e-03  7.945571e-03  8.295382e-03
## ASV1122      1.960109e-02  2.040039e-02  2.122803e-02  2.208474e-02
## ASV0123     -1.045135e-02 -1.078783e-02 -1.113102e-02 -1.148088e-02
## ASV2064      4.390487e-03  4.478984e-03  4.564712e-03  4.647272e-03
## ASV4459     -4.574447e-04 -4.634875e-04 -4.696388e-04 -4.759826e-04
## ASV0448      5.854910e-03  6.118616e-03  6.393027e-03  6.678463e-03
## ASV0397      1.064297e-02  1.103775e-02  1.144386e-02  1.186142e-02
## ASV0485      1.192757e-02  1.235448e-02  1.279298e-02  1.324321e-02
## ASV1566      1.809350e-02  1.876012e-02  1.944571e-02  2.015053e-02
## ASV1365      1.593145e-02  1.653096e-02  1.714742e-02  1.778093e-02
## ASV1065      2.272321e-02  2.359479e-02  2.449345e-02  2.541967e-02
## ASV0722     -1.426745e-03 -1.496857e-03 -1.570620e-03 -1.648229e-03
## ASV12660    -1.118748e-02 -1.154197e-02 -1.190305e-02 -1.227064e-02
## ASV0223      3.373689e-03  3.499624e-03  3.629497e-03  3.763408e-03
## ASV0229      5.718731e-03  5.956762e-03  6.203719e-03  6.459888e-03
## ASV0877      1.218131e-03  1.205748e-03  1.187644e-03  1.163246e-03
## ASV0983      1.151899e-02  1.191247e-02  1.231499e-02  1.272653e-02
## ASV0626      2.721708e-03  2.879573e-03  3.045240e-03  3.218945e-03
## ASV4146      2.320335e-04  2.088402e-04  1.812255e-04  1.487100e-04
## ASV4175     -1.617382e-02 -1.681900e-02 -1.748562e-02 -1.817408e-02
## ASV2082     -1.064738e-02 -1.123375e-02 -1.185153e-02 -1.250214e-02
## ASV2272      7.709658e-03  8.024998e-03  8.351947e-03  8.690856e-03
## ASV2245     -1.174171e-02 -1.221696e-02 -1.270835e-02 -1.321620e-02
## ASV0590     -1.078590e-02 -1.139447e-02 -1.203580e-02 -1.271136e-02
## ASV0217      2.674254e-03  2.864258e-03  3.065477e-03  3.278370e-03
## ASV0416      5.810643e-03  5.919770e-03  6.024947e-03  6.125704e-03
## ASV1056      1.184813e-02  1.234793e-02  1.286584e-02  1.340225e-02
## ASV7777     -1.567180e-02 -1.630659e-02 -1.696458e-02 -1.764656e-02
## ASV0455      2.674472e-03  2.772872e-03  2.873821e-03  2.977307e-03
## ASV0604      8.088513e-03  8.442224e-03  8.809646e-03  9.191162e-03
## ASV6100     -1.129204e-02 -1.177213e-02 -1.227126e-02 -1.279014e-02
## ASV11359    -2.284993e-02 -2.373610e-02 -2.464954e-02 -2.559060e-02
## ASV6604      3.510662e-03  3.662126e-03  3.819235e-03  3.982108e-03
## ASV5004     -8.056466e-03 -8.373058e-03 -8.700491e-03 -9.039084e-03
## ASV1483     -3.354598e-03 -3.478515e-03 -3.605900e-03 -3.736786e-03
## ASV9773     -1.063460e-02 -1.107084e-02 -1.152306e-02 -1.199175e-02
## ASV4059      1.670754e-03  1.806608e-03  1.951125e-03  2.104648e-03
## ASV1193      1.197783e-02  1.242945e-02  1.289480e-02  1.337413e-02
## ASV4610      4.104675e-05  1.136866e-04  1.918761e-04  2.757430e-04
## ASV0742      5.816009e-04  6.725007e-04  7.698642e-04  8.739038e-04
## ASV1502     -1.726187e-03 -1.839682e-03 -1.959369e-03 -2.085457e-03
## ASV0195     -3.789605e-04 -4.208189e-04 -4.655940e-04 -5.134100e-04
## ASV1213      6.747554e-03  6.928666e-03  7.110672e-03  7.293360e-03
## ASV1648     -1.014139e-02 -1.057492e-02 -1.102604e-02 -1.149546e-02
## ASV6984     -9.566877e-03 -9.980463e-03 -1.041121e-02 -1.085982e-02
## ASV0396      1.630620e-04  1.882548e-04  2.144343e-04  2.415022e-04
## ASV4297      1.034070e-02  1.064908e-02  1.096181e-02  1.127871e-02
## ASV2622      1.748111e-02  1.807632e-02  1.868570e-02  1.930931e-02
## ASV3512      1.023395e-02  1.076105e-02  1.131494e-02  1.189686e-02
## ASV2411      1.487768e-02  1.552440e-02  1.619628e-02  1.689405e-02
## ASV2291     -9.506207e-03 -1.004068e-02 -1.060298e-02 -1.119419e-02
## ASV0807      1.752792e-02  1.817473e-02  1.883940e-02  1.952205e-02
## ASV1292      3.091398e-03  3.160155e-03  3.228368e-03  3.295963e-03
## ASV1035      1.463779e-02  1.513237e-02  1.563916e-02  1.615830e-02
## ASV0070      9.854610e-04  1.061751e-03  1.143076e-03  1.229692e-03
## ASV0255      9.992998e-04  1.006710e-03  1.011663e-03  1.013882e-03
## ASV0057     -3.497011e-03 -3.585906e-03 -3.674603e-03 -3.762930e-03
## ASV0077     -4.559158e-04 -4.532424e-04 -4.494215e-04 -4.444108e-04
## ASV0625      8.019739e-03  8.265614e-03  8.515360e-03  8.768866e-03
## ASV2464      5.464295e-02  5.635528e-02  5.809930e-02  5.987467e-02
## ASV1315      1.965899e-02  2.052508e-02  2.142560e-02  2.236155e-02
## ASV2673      1.695362e-02  1.770566e-02  1.848811e-02  1.930195e-02
## ASV2161      7.168419e-03  7.490882e-03  7.827086e-03  8.177548e-03
## ASV0337     -3.740431e-03 -3.892510e-03 -4.049988e-03 -4.213012e-03
## ASV7680     -2.488032e-02 -2.590832e-02 -2.697352e-02 -2.807691e-02
## ASV0611      1.401002e-02  1.459917e-02  1.521075e-02  1.584548e-02
## ASV3118     -1.578539e-02 -1.649078e-02 -1.722471e-02 -1.798808e-02
## ASV1284     -6.413039e-04 -9.191895e-04 -1.224037e-03 -1.557587e-03
## ASV0889      9.193953e-03  9.527931e-03  9.871939e-03  1.022624e-02
## ASV4649     -5.029555e-03 -5.228663e-03 -5.434571e-03 -5.647460e-03
## ASV1108     -1.245072e-02 -1.303698e-02 -1.364912e-02 -1.428807e-02
## ASV0738      8.152474e-03  8.586056e-03  9.041999e-03  9.521324e-03
## ASV0473     -1.903500e-03 -2.001576e-03 -2.103417e-03 -2.209006e-03
## ASV0598     -4.658219e-03 -4.924958e-03 -5.206615e-03 -5.503919e-03
## ASV0429      6.218174e-03  6.406553e-03  6.597242e-03  6.790060e-03
## ASV1549      1.574198e-02  1.644323e-02  1.717284e-02  1.793169e-02
## ASV1203      1.000577e-02  1.035804e-02  1.071905e-02  1.108883e-02
## ASV4532      1.820653e-04  1.833290e-04  1.848559e-04  1.867322e-04
## ASV0274      2.342313e-03  2.446844e-03  2.554942e-03  2.666609e-03
## ASV0163     -6.985782e-03 -7.207486e-03 -7.433944e-03 -7.665218e-03
## ASV1298      6.613436e-04  6.884556e-04  7.178029e-04  7.496574e-04
## ASV9424     -1.982416e-02 -2.067673e-02 -2.156338e-02 -2.248534e-02
## ASV0412      1.702759e-02  1.761834e-02  1.822365e-02  1.884358e-02
## ASV0284      2.309759e-03  2.327871e-03  2.341557e-03  2.350404e-03
## ASV0620     -5.510039e-03 -5.795811e-03 -6.095452e-03 -6.409508e-03
## ASV0153     -2.086510e-02 -2.178340e-02 -2.273777e-02 -2.372921e-02
## ASV0498      6.680749e-03  6.939450e-03  7.205391e-03  7.478541e-03
## ASV0097      4.136141e-03  4.320526e-03  4.512377e-03  4.711920e-03
## ASV0104     -2.413514e-02 -2.500792e-02 -2.590363e-02 -2.682236e-02
## ASV1282      7.113853e-03  7.307346e-03  7.500452e-03  7.692658e-03
## ASV3883     -8.848147e-03 -9.265421e-03 -9.700138e-03 -1.015278e-02
## ASV0801      3.681664e-03  3.837138e-03  3.998878e-03  4.167157e-03
## ASV1611     -1.821805e-02 -1.901237e-02 -1.983828e-02 -2.069678e-02
## ASV0227     -4.589070e-03 -4.837485e-03 -5.098437e-03 -5.372431e-03
## ASV0833      5.711553e-03  5.938368e-03  6.172628e-03  6.414478e-03
## ASV0718      2.547403e-02  2.649310e-02  2.754680e-02  2.863591e-02
## ASV1139      1.044097e-03  9.877975e-04  9.230894e-04  8.494214e-04
## ASV0766     -4.427854e-03 -4.637057e-03 -4.855047e-03 -5.082073e-03
## ASV2091      1.677117e-02  1.727704e-02  1.778971e-02  1.830882e-02
## ASV1238     -2.053650e-02 -2.145136e-02 -2.240620e-02 -2.340277e-02
## ASV9193     -3.894435e-03 -4.146808e-03 -4.414848e-03 -4.699394e-03
## ASV0290      1.536975e-03  1.560659e-03  1.583869e-03  1.606657e-03
## ASV0231      6.637122e-03  6.859916e-03  7.087197e-03  7.318859e-03
## ASV0185      6.181861e-03  6.508501e-03  6.851826e-03  7.212579e-03
## ASV2330      6.646549e-03  6.833140e-03  7.021761e-03  7.212324e-03
## ASV3119     -5.456008e-03 -5.738258e-03 -6.034499e-03 -6.345325e-03
## ASV2368     -1.126890e-02 -1.179969e-02 -1.235520e-02 -1.293651e-02
## ASV0122     -4.292503e-03 -4.447394e-03 -4.606522e-03 -4.769934e-03
## ASV1044      1.314269e-02  1.371864e-02  1.431792e-02  1.494134e-02
## ASV0160     -3.947752e-03 -4.064315e-03 -4.182798e-03 -4.303215e-03
## ASV0326      1.297119e-03  1.344479e-03  1.392857e-03  1.442209e-03
## ASV1388      2.245221e-02  2.326109e-02  2.409128e-02  2.494288e-02
## ASV0792      1.539513e-02  1.589485e-02  1.640414e-02  1.692282e-02
## ASV0036     -6.226647e-03 -6.496773e-03 -6.776991e-03 -7.067523e-03
## ASV2125      1.642981e-02  1.703733e-02  1.766170e-02  1.830305e-02
## ASV1075     -3.241493e-04 -3.430710e-04 -3.633604e-04 -3.851277e-04
## ASV0390      1.059740e-02  1.108496e-02  1.159416e-02  1.212588e-02
## ASV3790     -1.361780e-02 -1.418105e-02 -1.476489e-02 -1.536990e-02
## ASV1535     -5.064636e-03 -5.319500e-03 -5.586246e-03 -5.865293e-03
## ASV0263      1.588779e-02  1.650927e-02  1.715096e-02  1.781328e-02
## ASV0675      2.578187e-02  2.687664e-02  2.801295e-02  2.919199e-02
## ASV3348      2.398065e-03  2.510672e-03  2.628002e-03  2.750185e-03
## ASV0058     -6.569025e-03 -6.801816e-03 -7.040393e-03 -7.284754e-03
## ASV4142      8.442845e-03  8.709330e-03  8.980649e-03  9.256748e-03
## ASV0059     -5.159220e-03 -5.335842e-03 -5.516411e-03 -5.700893e-03
## ASV0013     -1.001584e-02 -1.040144e-02 -1.079909e-02 -1.120902e-02
## ASV0033     -5.376826e-03 -5.609527e-03 -5.850984e-03 -6.101404e-03
## ASV4354     -6.124431e-03 -6.377003e-03 -6.639128e-03 -6.911116e-03
## ASV0022     -4.546920e-03 -4.744786e-03 -4.950252e-03 -5.163515e-03
## ASV0134     -4.847159e-03 -5.083281e-03 -5.330627e-03 -5.589700e-03
## ASV0415      9.737267e-04  1.022433e-03  1.073060e-03  1.125635e-03
## ASV10103    -2.447986e-02 -2.552313e-02 -2.660620e-02 -2.773023e-02
## ASV1613      1.449403e-02  1.495181e-02  1.541656e-02  1.588789e-02
## ASV0135     -1.621481e-03 -1.661556e-03 -1.701430e-03 -1.741018e-03
## ASV0469     -2.016116e-02 -2.089355e-02 -2.164720e-02 -2.242254e-02
## ASV0471      1.300498e-02  1.350707e-02  1.402552e-02  1.456074e-02
## ASV0451     -3.591376e-03 -3.792218e-03 -4.003314e-03 -4.225043e-03
## ASV0747      7.655257e-03  7.956584e-03  8.267414e-03  8.587873e-03
## ASV1314     -8.885500e-03 -9.298661e-03 -9.730341e-03 -1.018129e-02
## ASV0425     -2.290881e-02 -2.364049e-02 -2.438614e-02 -2.514559e-02
## ASV0559     -6.681706e-03 -6.958683e-03 -7.247021e-03 -7.547227e-03
## ASV0148     -4.053622e-04 -3.700645e-04 -3.299282e-04 -2.846079e-04
## ASV0129      3.603608e-03  3.840173e-03  4.091318e-03  4.357793e-03
## ASV1072      1.031468e-03  1.035926e-03  1.037917e-03  1.037223e-03
## ASV2390      1.058708e-02  1.085611e-02  1.112386e-02  1.138971e-02
## ASV0548      8.776752e-03  9.103746e-03  9.440071e-03  9.785825e-03
## ASV0168     -4.266017e-03 -4.416426e-03 -4.570766e-03 -4.729079e-03
## ASV0066     -4.860292e-03 -5.029506e-03 -5.202498e-03 -5.379204e-03
## ASV0468     -2.856171e-03 -2.972807e-03 -3.093782e-03 -3.219247e-03
## ASV0172     -9.087173e-04 -9.137086e-04 -9.167143e-04 -9.175573e-04
## ASV0236      2.197533e-03  2.392478e-03  2.600907e-03  2.823490e-03
## ASV0250      9.732867e-03  1.022369e-02  1.073868e-02  1.127889e-02
## ASV0338      3.831483e-03  3.986429e-03  4.145990e-03  4.310160e-03
## ASV0450     -1.215220e-03 -1.288387e-03 -1.365780e-03 -1.447609e-03
## ASV0377      6.051090e-03  6.261847e-03  6.477379e-03  6.697617e-03
## ASV1022     -7.397578e-05 -6.308392e-05 -5.043641e-05 -3.585893e-05
## ASV6174     -4.838924e-04 -5.190614e-04 -5.563729e-04 -5.958895e-04
## ASV0786     -1.829921e-03 -1.935753e-03 -2.046734e-03 -2.162997e-03
## ASV0053     -7.136932e-03 -7.415603e-03 -7.703151e-03 -7.999730e-03
## ASV0697     -3.821482e-03 -3.952479e-03 -4.086867e-03 -4.224706e-03
## ASV0785      8.441289e-03  8.741942e-03  9.050438e-03  9.366843e-03
## ASV1967     -8.297664e-03 -8.595412e-03 -8.901437e-03 -9.215853e-03
## ASV0385      3.478233e-03  3.627162e-03  3.781147e-03  3.940226e-03
## ASV0295      1.346356e-03  1.436450e-03  1.532154e-03  1.633758e-03
## ASV0072     -6.154531e-03 -6.350583e-03 -6.549637e-03 -6.751516e-03
## ASV0157      3.584056e-04  4.329286e-04  5.144089e-04  6.033081e-04
## ASV0501      1.556300e-02  1.617210e-02  1.680003e-02  1.744699e-02
## ASV10729    -2.020863e-02 -2.103928e-02 -2.189965e-02 -2.279052e-02
## ASV1470      7.476566e-03  7.664500e-03  7.851414e-03  8.036841e-03
## ASV0050     -1.554758e-02 -1.610224e-02 -1.667095e-02 -1.725373e-02
## ASV0411     -4.208811e-03 -4.395103e-03 -4.589160e-03 -4.791280e-03
## ASV0549      6.469724e-03  6.740486e-03  7.021103e-03  7.311821e-03
## ASV0184      1.986936e-03  2.066947e-03  2.150086e-03  2.236494e-03
## ASV0705      3.453424e-03  3.561204e-03  3.670324e-03  3.780645e-03
## ASV1715      8.454986e-03  8.784054e-03  9.123548e-03  9.473646e-03
## ASV0603      1.582510e-03  1.662091e-03  1.746056e-03  1.834672e-03
## ASV0826      1.370483e-02  1.421764e-02  1.474578e-02  1.528953e-02
## ASV0034     -4.054347e-03 -4.188873e-03 -4.326066e-03 -4.465874e-03
## ASV0838      1.038124e-04 -4.726869e-05 -2.157659e-04 -4.030225e-04
## ASV0614     -3.735411e-03 -3.874401e-03 -4.017461e-03 -4.164651e-03
## ASV0014     -1.003053e-02 -1.040650e-02 -1.079342e-02 -1.119142e-02
## ASV0585     -8.709714e-04 -9.904750e-04 -1.119048e-03 -1.257088e-03
## ASV0016     -1.048848e-02 -1.088207e-02 -1.128717e-02 -1.170391e-02
## ASV5394     -8.246774e-03 -8.572510e-03 -8.908684e-03 -9.255446e-03
## ASV0666      1.532784e-02  1.582559e-02  1.633300e-02  1.684994e-02
## ASV2085      7.092926e-04  5.925433e-04  4.626064e-04  3.186765e-04
## ASV0003     -7.138575e-03 -7.406037e-03 -7.681310e-03 -7.964495e-03
## ASV0346      4.178784e-03  4.357639e-03  4.542802e-03  4.734368e-03
## ASV0267      6.071830e-04  6.552261e-04  7.058663e-04  7.591266e-04
## ASV0353      6.488776e-03  6.768552e-03  7.059128e-03  7.360821e-03
## ASV2419      1.492526e-02  1.546523e-02  1.601953e-02  1.658823e-02
## ASV0447      9.548187e-03  9.958785e-03  1.038502e-02  1.082734e-02
## ASV0654      1.245015e-02  1.291613e-02  1.339537e-02  1.388798e-02
## ASV0151      2.515492e-03  2.650913e-03  2.793244e-03  2.942767e-03
## ASV0065     -4.653240e-03 -4.821123e-03 -4.993465e-03 -5.170299e-03
## ASV0527      1.172938e-02  1.216650e-02  1.261622e-02  1.307869e-02
## ASV4055     -2.634465e-03 -2.778768e-03 -2.931602e-03 -3.093505e-03
## ASV0166     -5.305171e-03 -5.476708e-03 -5.651482e-03 -5.829440e-03
## ASV0417     -1.770892e-03 -1.808146e-03 -1.844528e-03 -1.879906e-03
## ASV0078     -3.170804e-03 -3.271243e-03 -3.373036e-03 -3.476060e-03
## ASV0322      2.555285e-04  3.178971e-04  3.867750e-04  4.626401e-04
## ASV0156     -9.111793e-03 -9.493373e-03 -9.889431e-03 -1.030043e-02
## ASV0648     -1.999656e-02 -2.083468e-02 -2.170376e-02 -2.260464e-02
## ASV0407     -1.679393e-03 -1.759271e-03 -1.842907e-03 -1.930471e-03
## ASV2030     -3.188298e-03 -3.332586e-03 -3.484225e-03 -3.643644e-03
## ASV0300      2.563828e-03  2.677239e-03  2.795061e-03  2.917405e-03
## ASV1150      7.367919e-04  7.741936e-04  8.131780e-04  8.537700e-04
## ASV0958      8.175875e-03  8.557412e-03  8.956053e-03  9.372483e-03
## ASV0216     -7.291491e-03 -7.573029e-03 -7.864698e-03 -8.166901e-03
## ASV0446      1.223056e-02  1.273439e-02  1.325585e-02  1.379533e-02
## ASV0367     -7.737996e-03 -8.048281e-03 -8.369153e-03 -8.700853e-03
## ASV0200     -4.539265e-03 -4.716481e-03 -4.899183e-03 -5.087433e-03
## ASV0334     -1.413383e-03 -1.431867e-03 -1.449367e-03 -1.465870e-03
## ASV1311      1.940155e-03  1.969243e-03  1.995986e-03  2.020127e-03
## ASV0458      2.775175e-03  2.817858e-03  2.857842e-03  2.894861e-03
## ASV1371      8.815603e-04  9.200667e-04  9.597273e-04  1.000517e-03
## ASV0418      8.581071e-03  8.856489e-03  9.137184e-03  9.423084e-03
## ASV0004      1.203770e-03  1.240357e-03  1.277486e-03  1.315136e-03
## ASV1943      1.752517e-02  1.784473e-02  1.815588e-02  1.845777e-02
## ASV1495     -3.977861e-03 -4.225277e-03 -4.487309e-03 -4.764682e-03
## ASV0901     -9.393921e-03 -9.807758e-03 -1.023885e-02 -1.068787e-02
## ASV0628      3.346671e-03  3.423452e-03  3.498899e-03  3.572736e-03
## ASV0400      2.333199e-03  2.401879e-03  2.470833e-03  2.539895e-03
## ASV0116     -2.727553e-03 -2.845434e-03 -2.968003e-03 -3.095419e-03
## ASV0788      2.437513e-02  2.544209e-02  2.655269e-02  2.770850e-02
## ASV0117      1.966827e-03  2.058503e-03  2.154113e-03  2.253789e-03
## ASV3137     -4.492227e-04 -4.630937e-04 -4.770690e-04 -4.911142e-04
## ASV0001      1.261201e-03  1.297717e-03  1.334625e-03  1.371899e-03
## ASV1651      3.763965e-03  3.882780e-03  4.003783e-03  4.126951e-03
## ASV1692      2.005420e-02  2.091638e-02  2.181231e-02  2.274309e-02
## ASV0660      4.521561e-03  4.601212e-03  4.676382e-03  4.746518e-03
## ASV0508      2.099686e-04  2.130041e-04  2.157488e-04  2.181619e-04
## ASV1660     -4.739409e-03 -4.964724e-03 -5.199483e-03 -5.443935e-03
## ASV0233      5.762212e-03  5.991343e-03  6.228203e-03  6.472970e-03
## ASV1343     -1.132985e-02 -1.181540e-02 -1.232009e-02 -1.284456e-02
## ASV0209      4.242920e-03  4.365940e-03  4.490099e-03  4.615250e-03
## ASV0193     -5.079297e-03 -5.229929e-03 -5.381963e-03 -5.535191e-03
## ASV0357      3.533281e-03  3.732022e-03  3.942034e-03  4.163912e-03
## ASV0198      4.330278e-03  4.489115e-03  4.652728e-03  4.821233e-03
## ASV0007      1.039421e-03  1.065635e-03  1.091808e-03  1.117898e-03
## ASV1772     -1.045757e-03 -1.025232e-03 -9.980483e-04 -9.634727e-04
## ASV0009      7.938724e-04  8.103622e-04  8.265039e-04  8.422519e-04
## ASV0006     -1.478580e-03 -1.546610e-03 -1.617508e-03 -1.691366e-03
## ASV0011     -4.569213e-03 -4.759091e-03 -4.955920e-03 -5.159893e-03
## ASV0015      5.858094e-04  5.967330e-04  6.072282e-04  6.172427e-04
## ASV0017      6.769832e-04  6.911514e-04  7.050187e-04  7.185410e-04
## ASV0235     -4.293883e-03 -4.475250e-03 -4.663497e-03 -4.858841e-03
## ASV0382      3.181013e-03  3.297668e-03  3.416542e-03  3.537467e-03
## ASV2357      1.377795e-02  1.435514e-02  1.495412e-02  1.557558e-02
## ASV0567     -2.855340e-03 -2.987965e-03 -3.126917e-03 -3.272512e-03
## ASV0165      2.258710e-03  2.349708e-03  2.443729e-03  2.540829e-03
## ASV0005      3.030538e-03  3.142173e-03  3.256834e-03  3.374533e-03
## ASV0384      2.954901e-04  3.381762e-04  3.846385e-04  4.351312e-04
## ASV0002      5.183528e-04  5.362452e-04  5.546210e-04  5.734892e-04
## ASV3017      1.406620e-02  1.449991e-02  1.493999e-02  1.538614e-02
## ASV0091     -4.245030e-04 -4.436469e-04 -4.638425e-04 -4.851685e-04
## ASV0186     -6.220565e-03 -6.453197e-03 -6.692187e-03 -6.937537e-03
## ASV0370      3.103752e-03  3.213238e-03  3.325585e-03  3.440833e-03
## ASV0018      3.938040e-03  4.085985e-03  4.238185e-03  4.394680e-03
## ASV1377      3.545077e-02  3.661447e-02  3.780117e-02  3.901053e-02
## ASV0019      4.154244e-03  4.311517e-03  4.473420e-03  4.640007e-03
## ASV0023     -2.855046e-03 -2.974755e-03 -3.098753e-03 -3.227133e-03
## ASV2194      4.901196e-03  5.125567e-03  5.359794e-03  5.604269e-03
## ASV1155      1.508516e-02  1.561788e-02  1.616568e-02  1.672889e-02
## ASV0510     -3.291262e-03 -3.371648e-03 -3.452393e-03 -3.533495e-03
## ASV2371     -9.004436e-03 -9.311632e-03 -9.626132e-03 -9.947932e-03
## ASV0024     -3.525991e-03 -3.672844e-03 -3.824926e-03 -3.982353e-03
## ASV2452      7.719630e-03  7.908548e-03  8.096125e-03  8.281929e-03
## ASV2332     -2.692960e-02 -2.790623e-02 -2.891134e-02 -2.994546e-02
## ASV2591      1.001796e-02  1.048049e-02  1.096027e-02  1.145753e-02
## ASV0521      7.196724e-03  7.501128e-03  7.817053e-03  8.144842e-03
## ASV5542      6.768957e-03  7.043534e-03  7.327495e-03  7.621060e-03
## ASV0336     -1.482256e-03 -1.568504e-03 -1.659386e-03 -1.755109e-03
## ASV10102     1.252319e-02  1.303518e-02  1.356462e-02  1.411185e-02
## ASV16823    -1.487366e-02 -1.533095e-02 -1.579651e-02 -1.627026e-02
## ASV3104      7.695910e-02  7.932512e-02  8.173392e-02  8.418507e-02
## ASV0781      1.293710e-02  1.343407e-02  1.394714e-02  1.447673e-02
## ASV10899     1.090046e-02  1.146355e-02  1.205419e-02  1.267350e-02
## ASV11222    -2.617934e-02 -2.698416e-02 -2.780353e-02 -2.863730e-02
## ASV11327    -2.350427e-02 -2.422683e-02 -2.496245e-02 -2.571099e-02
## ASV12458    -2.617900e-02 -2.698376e-02 -2.780306e-02 -2.863675e-02
## ASV1636      1.636094e-02  1.692344e-02  1.749961e-02  1.808952e-02
## ASV1890     -1.053345e-02 -1.079802e-02 -1.106432e-02 -1.133223e-02
## ASV2898      2.202868e-02  2.279072e-02  2.357149e-02  2.437112e-02
## ASV8328      7.955577e-03  8.484012e-03  9.043917e-03  9.636772e-03
## ASV0709     -2.563242e-02 -2.655706e-02 -2.750612e-02 -2.847975e-02
## ASV0856      2.533282e-02  2.643596e-02  2.758159e-02  2.877088e-02
## ASV0909      1.055628e-02  1.114433e-02  1.176272e-02  1.241266e-02
## ASV0937     -1.730944e-02 -1.806583e-02 -1.885388e-02 -1.967484e-02
## ASV11390    -3.736281e-02 -3.851127e-02 -3.968047e-02 -4.087017e-02
## ASV11966     1.312458e-02  1.371610e-02  1.433095e-02  1.496973e-02
## ASV12990     6.945518e-03  7.170171e-03  7.399445e-03  7.633354e-03
## ASV14797     1.002629e-02  1.034396e-02  1.066784e-02  1.099794e-02
## ASV14904    -5.361436e-02 -5.526230e-02 -5.693997e-02 -5.864707e-02
## ASV15304     9.086372e-03  9.522945e-03  9.977977e-03  1.045198e-02
## ASV16696    -1.852466e-02 -1.909404e-02 -1.967368e-02 -2.026348e-02
## ASV1690      4.249565e-02  4.428210e-02  4.612985e-02  4.803985e-02
## ASV2029      2.518426e-02  2.610872e-02  2.705992e-02  2.803828e-02
## ASV2834      3.449406e-02  3.587366e-02  3.729858e-02  3.876958e-02
## ASV4003      3.395934e-02  3.560587e-02  3.733097e-02  3.913821e-02
## ASV4064      1.673691e-02  1.742170e-02  1.813030e-02  1.886328e-02
## ASV4294      1.292768e-02  1.358235e-02  1.426862e-02  1.498779e-02
## ASV4609      8.504303e-03  8.819822e-03  9.145500e-03  9.481659e-03
## ASV6283     -1.731645e-02 -1.784867e-02 -1.839048e-02 -1.894178e-02
## ASV6491     -2.481973e-02 -2.558254e-02 -2.635910e-02 -2.714927e-02
## ASV7453      1.774533e-02  1.855855e-02  1.940474e-02  2.028481e-02
## ASV7959      8.278445e-03  8.729881e-03  9.204362e-03  9.702872e-03
## ASV8219      2.144952e-01  2.210873e-01  2.277983e-01  2.346268e-01
## ASV8547     -2.222106e-02 -2.290397e-02 -2.359920e-02 -2.430660e-02
## ASV9319      1.325698e-02  1.384156e-02  1.445017e-02  1.508368e-02
## ASV9382     -4.347839e-02 -4.481459e-02 -4.617486e-02 -4.755897e-02
## ASV11516    -2.903999e-02 -2.993245e-02 -3.084100e-02 -3.176546e-02
## ASV14377    -2.096839e-02 -2.161279e-02 -2.226880e-02 -2.293630e-02
## ASV1867      2.110199e-02  2.198149e-02  2.289338e-02  2.383860e-02
## ASV1895      7.367171e-03  7.528658e-03  7.686438e-03  7.839899e-03
## ASV3168      1.036736e-02  1.067168e-02  1.097932e-02  1.129003e-02
## ASV4449      6.839356e-02  7.108026e-02  7.385908e-02  7.673257e-02
## ASV6596      1.837910e-02  1.928417e-02  2.023207e-02  2.122457e-02
## ASV7492      9.725018e-04  1.155993e-03  1.354127e-03  1.567628e-03
## ASV9854     -4.321999e-03 -4.450298e-03 -4.580676e-03 -4.713086e-03
## ASV6296      3.518627e-01  3.626760e-01  3.736842e-01  3.848852e-01
## ASV4201      6.049586e-03  6.462230e-03  6.900343e-03  7.365225e-03
## ASV0552      1.432824e-02  1.490891e-02  1.550924e-02  1.612958e-02
## ASV3671     -9.063681e-03 -9.439461e-03 -9.831180e-03 -1.023962e-02
## ASV3529      2.123388e-04  3.113019e-04  4.175133e-04  5.311735e-04
## ASV1060      4.334856e-03  4.541429e-03  4.757888e-03  4.984702e-03
## ASV0239     -3.768638e-03 -3.867978e-03 -3.967738e-03 -4.067795e-03
## ASV5711     -2.075529e-02 -2.151044e-02 -2.228747e-02 -2.308674e-02
## ASV4152     -3.197290e-02 -3.323745e-02 -3.454364e-02 -3.589226e-02
## ASV1461      1.245965e-02  1.279933e-02  1.314125e-02  1.348506e-02
## ASV2877      6.676581e-03  6.864757e-03  7.054181e-03  7.244593e-03
## ASV0012      1.426124e-03  1.482150e-03  1.540057e-03  1.599889e-03
## ASV9823      5.359462e-04  4.817835e-04  4.201440e-04  3.504774e-04
## ASV0008      1.494311e-03  1.552079e-03  1.611748e-03  1.673365e-03
## ASV7832     -1.944786e-02 -2.025408e-02 -2.109001e-02 -2.195647e-02
## ASV1915     -2.263506e-03 -2.358192e-03 -2.457185e-03 -2.560709e-03
## ASV0055     -2.229151e-03 -2.342788e-03 -2.461947e-03 -2.586857e-03
## ASV0032      4.199790e-04  4.227384e-04  4.248695e-04  4.263449e-04
## ASV2977     -2.616116e-02 -2.717694e-02 -2.822467e-02 -2.930480e-02
## ASV0466      1.654526e-02  1.699450e-02  1.744582e-02  1.789858e-02
## ASV3866      1.578895e-02  1.647364e-02  1.718593e-02  1.792681e-02
## ASV0040      5.365582e-03  5.582142e-03  5.806190e-03  6.037904e-03
## ASV0496     -3.103165e-03 -3.305136e-03 -3.518718e-03 -3.744392e-03
## ASV0052      4.525633e-03  4.709342e-03  4.899543e-03  5.096409e-03
## ASV3828     -1.236017e-02 -1.273407e-02 -1.311423e-02 -1.350053e-02
## ASV1930      6.683842e-03  6.889167e-03  7.097174e-03  7.307687e-03
## ASV2126      1.262605e-02  1.309309e-02  1.357412e-02  1.406944e-02
## ASV0793      1.748087e-02  1.821309e-02  1.897232e-02  1.975932e-02
## ASV0299     -6.114082e-04 -6.590091e-04 -7.107911e-04 -7.671096e-04
## ASV0208      1.220023e-02  1.269975e-02  1.321760e-02  1.375434e-02
## ASV0511     -3.611058e-03 -3.702132e-03 -3.793608e-03 -3.885453e-03
## ASV1123     -1.155217e-02 -1.187575e-02 -1.220223e-02 -1.253126e-02
## ASV0099      7.451395e-04  7.910201e-04  8.397806e-04  8.915851e-04
## ASV0752     -9.660411e-03 -1.009409e-02 -1.054577e-02 -1.101607e-02
## ASV0883      1.299286e-02  1.355905e-02  1.414680e-02  1.475666e-02
## ASV0683      1.656246e-02  1.727587e-02  1.801688e-02  1.878634e-02
## ASV4117     -2.495390e-02 -2.598754e-02 -2.705995e-02 -2.817235e-02
## ASV2172      6.794826e-04  6.640228e-04  6.449860e-04  6.220860e-04
## ASV0330     -4.768880e-03 -4.970032e-03 -5.178962e-03 -5.395934e-03
## ASV0728      2.169547e-02  2.251759e-02  2.336462e-02  2.423699e-02
## ASV0499      6.565680e-03  6.854709e-03  7.155391e-03  7.468106e-03
## ASV0120     -9.662141e-03 -1.002650e-02 -1.040130e-02 -1.078661e-02
## ASV1446      4.262204e-03  4.285067e-03  4.298963e-03  4.303091e-03
## ASV17171    -1.908070e-02 -1.984923e-02 -2.064582e-02 -2.147137e-02
## ASV0533      1.791950e-03  1.878520e-03  1.968958e-03  2.063397e-03
## ASV2495     -6.730631e-03 -7.092669e-03 -7.473226e-03 -7.873047e-03
## ASV5582      5.836509e-03  5.940084e-03  6.039289e-03  6.133619e-03
## ASV1488      2.789354e-03  2.867045e-03  2.944596e-03  3.021788e-03
## ASV0682      4.844907e-03  5.058994e-03  5.281585e-03  5.512925e-03
## ASV0068     -7.434106e-03 -7.718486e-03 -8.011106e-03 -8.312008e-03
## ASV1987     -2.149865e-02 -2.246774e-02 -2.347667e-02 -2.452673e-02
## ASV0035     -2.770352e-03 -2.950964e-03 -3.143261e-03 -3.347934e-03
## ASV7192     -1.062052e-02 -1.099540e-02 -1.137959e-02 -1.177307e-02
## ASV0873     -2.005561e-02 -2.154685e-02 -2.312357e-02 -2.478881e-02
## ASV4749     -4.172060e-03 -4.504880e-03 -4.859700e-03 -5.237594e-03
## ASV2174      5.549417e-03  5.656306e-03  5.759441e-03  5.858342e-03
## ASV1476     -9.464306e-03 -9.897117e-03 -1.034864e-02 -1.081955e-02
## ASV0740     -2.625586e-02 -2.742248e-02 -2.863751e-02 -2.990267e-02
## ASV0170     -4.651564e-03 -4.838071e-03 -5.031079e-03 -5.230766e-03
## ASV2466     -2.146530e-02 -2.234425e-02 -2.325534e-02 -2.419952e-02
## ASV1709      7.271727e-03  7.570379e-03  7.882596e-03  8.209206e-03
## ASV6170     -3.531281e-02 -3.681983e-02 -3.838476e-02 -4.000937e-02
## ASV3673      1.794128e-02  1.873078e-02  1.955194e-02  2.040575e-02
## ASV1745     -5.227667e-03 -5.481078e-03 -5.746020e-03 -6.022917e-03
##                                                                    
## (Intercept)  1.285165e-01  1.333019e-01  1.382228e-01  1.432804e-01
## ASV1236      2.219021e-02  2.291603e-02  2.365796e-02  2.441605e-02
## ASV0421      5.004078e-03  5.268741e-03  5.545090e-03  5.833379e-03
## ASV0691     -1.276293e-02 -1.301038e-02 -1.325446e-02 -1.349490e-02
## ASV0899      1.900804e-02  1.959764e-02  2.019699e-02  2.080586e-02
## ASV1004      4.448540e-02  4.592046e-02  4.738483e-02  4.887837e-02
## ASV1041     -1.719403e-02 -1.767043e-02 -1.814890e-02 -1.862870e-02
## ASV1058      2.779713e-02  2.870447e-02  2.963178e-02  3.057912e-02
## ASV12542     9.922084e-03  1.021790e-02  1.051929e-02  1.082636e-02
## ASV1294      2.605152e-02  2.691249e-02  2.779350e-02  2.869475e-02
## ASV13113     1.225660e-02  1.282942e-02  1.342762e-02  1.405219e-02
## ASV1318      2.573523e-02  2.656805e-02  2.741850e-02  2.828660e-02
## ASV2269     -4.347990e-02 -4.481338e-02 -4.616783e-02 -4.754250e-02
## ASV2542      2.713911e-02  2.827416e-02  2.945191e-02  3.067365e-02
## ASV2660     -1.706593e-02 -1.758647e-02 -1.811571e-02 -1.865349e-02
## ASV2737      5.137902e-03  5.274197e-03  5.412475e-03  5.552793e-03
## ASV2840      2.028520e-02  2.078970e-02  2.129457e-02  2.179922e-02
## ASV3053      1.130157e-01  1.164036e-01  1.198520e-01  1.233607e-01
## ASV3077      7.409516e-03  7.644046e-03  7.883875e-03  8.129099e-03
## ASV3134      1.855024e-02  1.938312e-02  2.025116e-02  2.115567e-02
## ASV3140      2.136454e-02  2.216594e-02  2.299068e-02  2.383901e-02
## ASV3579      1.014700e-02  1.063639e-02  1.114713e-02  1.167986e-02
## ASV6119     -1.189590e-02 -1.226035e-02 -1.263048e-02 -1.300610e-02
## ASV7557     -2.417381e-02 -2.491429e-02 -2.566633e-02 -2.642951e-02
## ASV8422      5.838897e-03  6.021780e-03  6.208848e-03  6.400203e-03
## ASV1086     -6.987747e-04 -7.166620e-04 -7.351880e-04 -7.544281e-04
## ASV1310      1.172678e-02  1.209627e-02  1.247252e-02  1.285541e-02
## ASV15750    -1.158272e-03 -1.173126e-03 -1.186586e-03 -1.198526e-03
## ASV16905    -4.970311e-03 -5.122534e-03 -5.277135e-03 -5.434034e-03
## ASV2033      2.769624e-02  2.884521e-02  3.003461e-02  3.126533e-02
## ASV2089      1.050687e-02  1.082904e-02  1.115621e-02  1.148820e-02
## ASV2127      3.477750e-02  3.589983e-02  3.704581e-02  3.821547e-02
## ASV2725      2.611938e-02  2.688949e-02  2.767098e-02  2.846359e-02
## ASV2804     -1.028885e-02 -1.060397e-02 -1.092402e-02 -1.124885e-02
## ASV3075      2.667210e-02  2.772947e-02  2.882542e-02  2.996125e-02
## ASV3327      3.893199e-02  4.049228e-02  4.210509e-02  4.377154e-02
## ASV3342      3.294576e-02  3.425946e-02  3.561820e-02  3.702312e-02
## ASV3532     -3.519668e-02 -3.657479e-02 -3.800079e-02 -3.947617e-02
## ASV3600      1.650049e-02  1.714341e-02  1.780732e-02  1.849267e-02
## ASV4013      2.796205e-02  2.893011e-02  2.992170e-02  3.093686e-02
## ASV4136      2.699000e-02  2.783643e-02  2.870011e-02  2.958109e-02
## ASV4195      1.050317e-01  1.082491e-01  1.115170e-01  1.148339e-01
## ASV4407     -4.058254e-02 -4.182576e-02 -4.308853e-02 -4.437024e-02
## ASV4717      5.712821e-03  5.852145e-03  5.993075e-03  6.135706e-03
## ASV6794      1.573983e-02  1.621259e-02  1.669500e-02  1.718722e-02
## ASV8324     -2.082378e-02 -2.146183e-02 -2.210995e-02 -2.276782e-02
## ASV8981      7.224479e-04  8.056215e-04  8.949372e-04  9.906950e-04
## ASV9859      1.243339e-02  1.308931e-02  1.377931e-02  1.450501e-02
## ASV0936      2.446908e-02  2.540536e-02  2.636924e-02  2.736097e-02
## ASV12683    -2.848585e-04 -2.972802e-04 -3.094968e-04 -3.214074e-04
## ASV1293      1.348825e-02  1.390750e-02  1.433428e-02  1.476849e-02
## ASV13055     5.414393e-04  6.003173e-04  6.634190e-04  7.309464e-04
## ASV17063    -1.080733e-02 -1.113862e-02 -1.147515e-02 -1.181678e-02
## ASV2228      8.814101e-03  9.084308e-03  9.358802e-03  9.637455e-03
## ASV2769      2.534545e-03  2.659605e-03  2.789522e-03  2.924344e-03
## ASV2803      8.391284e-03  8.614109e-03  8.839275e-03  9.066730e-03
## ASV2896      1.004686e-02  1.048957e-02  1.095133e-02  1.143294e-02
## ASV3062      1.361593e-02  1.424151e-02  1.489252e-02  1.556964e-02
## ASV3107      1.770748e-02  1.842999e-02  1.917867e-02  1.995423e-02
## ASV3265      1.906317e-02  1.964502e-02  2.023664e-02  2.083785e-02
## ASV3666     -5.984483e-05 -7.416138e-05 -8.972418e-05 -1.065951e-04
## ASV4497      6.918963e-03  7.148247e-03  7.382715e-03  7.622384e-03
## ASV6914     -1.825109e-03 -1.917298e-03 -2.013487e-03 -2.113781e-03
## ASV0576     -1.962850e-02 -2.011340e-02 -2.060015e-02 -2.108836e-02
## ASV0673      2.748408e-02  2.842379e-02  2.938648e-02  3.037234e-02
## ASV0772      1.338114e-02  1.387422e-02  1.438236e-02  1.490591e-02
## ASV0862      4.282243e-03  4.542572e-03  4.815100e-03  5.100053e-03
## ASV0898      1.221859e-02  1.272525e-02  1.324922e-02  1.379084e-02
## ASV0910      1.347426e-02  1.402720e-02  1.460002e-02  1.519325e-02
## ASV0964     -7.757007e-03 -7.960443e-03 -8.165369e-03 -8.371661e-03
## ASV10059     1.074330e-02  1.122606e-02  1.172839e-02  1.225089e-02
## ASV10263    -1.645237e-02 -1.695722e-02 -1.747016e-02 -1.799095e-02
## ASV1088      2.365863e-02  2.463705e-02  2.565282e-02  2.670719e-02
## ASV1101      2.329714e-02  2.400916e-02  2.473297e-02  2.546833e-02
## ASV1183      7.326917e-03  7.607823e-03  7.897882e-03  8.197332e-03
## ASV11956     5.102567e-03  5.234313e-03  5.367678e-03  5.502699e-03
## ASV12774    -6.416441e-04 -7.046290e-04 -7.716489e-04 -8.428532e-04
## ASV1321      3.569668e-02  3.718434e-02  3.872539e-02  4.032105e-02
## ASV13793    -1.134512e-02 -1.169334e-02 -1.204713e-02 -1.240635e-02
## ASV14482     5.827853e-04  6.033046e-04  6.249536e-04  6.478207e-04
## ASV15483     5.750779e-03  5.977095e-03  6.210672e-03  6.451641e-03
## ASV2062      2.385055e-02  2.469639e-02  2.556549e-02  2.645822e-02
## ASV2132      2.174717e-02  2.260147e-02  2.348331e-02  2.439318e-02
## ASV2413      1.750946e-02  1.809636e-02  1.869771e-02  1.931369e-02
## ASV2490      4.860165e-02  5.000338e-02  5.142479e-02  5.286538e-02
## ASV2594      8.035826e-03  8.373522e-03  8.724947e-03  9.090647e-03
## ASV2822     -2.993381e-02 -3.085273e-02 -3.178638e-02 -3.273436e-02
## ASV2863      3.149438e-02  3.248004e-02  3.348534e-02  3.451029e-02
## ASV2910      1.172964e-02  1.210230e-02  1.248259e-02  1.287053e-02
## ASV2980      1.425321e-02  1.475163e-02  1.526282e-02  1.578691e-02
## ASV3307      2.382324e-02  2.455464e-02  2.529776e-02  2.605228e-02
## ASV3474      2.113155e-02  2.203629e-02  2.297492e-02  2.394830e-02
## ASV3502      1.920281e-02  1.992929e-02  2.067885e-02  2.145204e-02
## ASV4236      2.211396e-02  2.271009e-02  2.331143e-02  2.391762e-02
## ASV4842     -2.825225e-03 -2.900949e-03 -2.975630e-03 -3.048982e-03
## ASV4894     -1.134692e-02 -1.169531e-02 -1.204930e-02 -1.240872e-02
## ASV5290      1.082338e-02  1.123970e-02  1.166905e-02  1.211169e-02
## ASV5501      6.819058e-03  7.110053e-03  7.413637e-03  7.730389e-03
## ASV5795      7.425989e-03  7.717636e-03  8.018629e-03  8.329122e-03
## ASV5987     -3.169186e-02 -3.266499e-02 -3.365376e-02 -3.465774e-02
## ASV6267     -3.571305e-02 -3.680968e-02 -3.792393e-02 -3.905534e-02
## ASV6862      1.369467e-02  1.410743e-02  1.452783e-02  1.495586e-02
## ASV7145      6.072013e-03  6.271882e-03  6.477712e-03  6.689723e-03
## ASV7673     -1.134780e-02 -1.169628e-02 -1.205037e-02 -1.240993e-02
## ASV7789      9.236562e-03  9.699703e-03  1.018469e-02  1.069237e-02
## ASV7809      1.600618e-03  1.703291e-03  1.811285e-03  1.924752e-03
## ASV8002     -1.433274e-02 -1.477295e-02 -1.522025e-02 -1.567447e-02
## ASV8205      7.246385e-03  7.532619e-03  7.828564e-03  8.134447e-03
## ASV9155     -3.269682e-03 -3.351999e-03 -3.434255e-03 -3.516326e-03
## ASV9221      3.828667e-03  4.061662e-03  4.307533e-03  4.566831e-03
## ASV9311     -2.299505e-02 -2.370149e-02 -2.441937e-02 -2.514841e-02
## ASV9557     -1.571670e-02 -1.619959e-02 -1.669030e-02 -1.718867e-02
## ASV9936     -3.169756e-02 -3.267155e-02 -3.366137e-02 -3.466663e-02
## ASV1445      2.304584e-02  2.393536e-02  2.485297e-02  2.579916e-02
## ASV4232      1.076510e-02  1.128684e-02  1.183402e-02  1.240783e-02
## ASV6479      5.947785e-03  6.297549e-03  6.666528e-03  7.055582e-03
## ASV0142     -1.351283e-02 -1.393287e-02 -1.436091e-02 -1.479691e-02
## ASV0378      8.658347e-03  9.034734e-03  9.424795e-03  9.828768e-03
## ASV1122      2.297127e-02  2.388837e-02  2.483678e-02  2.581726e-02
## ASV0123     -1.183735e-02 -1.220038e-02 -1.256991e-02 -1.294587e-02
## ASV2064      4.726251e-03  4.801217e-03  4.871722e-03  4.937301e-03
## ASV4459     -4.826145e-04 -4.896440e-04 -4.971968e-04 -5.054155e-04
## ASV0448      6.975247e-03  7.283701e-03  7.604144e-03  7.936896e-03
## ASV0397      1.229060e-02  1.273150e-02  1.318426e-02  1.364901e-02
## ASV0485      1.370530e-02  1.417940e-02  1.466563e-02  1.516412e-02
## ASV1566      2.087480e-02  2.161877e-02  2.238263e-02  2.316661e-02
## ASV1365      1.843158e-02  1.909942e-02  1.978447e-02  2.048673e-02
## ASV1065      2.637390e-02  2.735659e-02  2.836819e-02  2.940910e-02
## ASV0722     -1.729892e-03 -1.815825e-03 -1.906251e-03 -2.001406e-03
## ASV12660    -1.264465e-02 -1.302497e-02 -1.341150e-02 -1.380413e-02
## ASV0223      3.901465e-03  4.043774e-03  4.190451e-03  4.341612e-03
## ASV0229      6.725560e-03  7.001036e-03  7.286624e-03  7.582642e-03
## ASV0877      1.131942e-03  1.093085e-03  1.045988e-03  9.899250e-04
## ASV0983      1.314705e-02  1.357650e-02  1.401483e-02  1.446197e-02
## ASV0626      3.400924e-03  3.591406e-03  3.790617e-03  3.998774e-03
## ASV4146      1.107805e-04  6.688663e-05  1.643944e-05 -4.118925e-05
## ASV4175     -1.888480e-02 -1.961818e-02 -2.037460e-02 -2.115444e-02
## ASV2082     -1.318707e-02 -1.390783e-02 -1.466595e-02 -1.546301e-02
## ASV2272      9.042086e-03  9.406004e-03  9.782980e-03  1.017339e-02
## ASV2245     -1.374083e-02 -1.428256e-02 -1.484169e-02 -1.541850e-02
## ASV0590     -1.342267e-02 -1.417127e-02 -1.495876e-02 -1.578675e-02
## ASV0217      3.503400e-03  3.741034e-03  3.991742e-03  4.255997e-03
## ASV0416      6.221554e-03  6.312003e-03  6.396540e-03  6.474650e-03
## ASV1056      1.395756e-02  1.453216e-02  1.512643e-02  1.574073e-02
## ASV7777     -1.835334e-02 -1.908576e-02 -1.984474e-02 -2.063118e-02
## ASV0455      3.083311e-03  3.191808e-03  3.302766e-03  3.416145e-03
## ASV0604      9.587155e-03  9.998006e-03  1.042410e-02  1.086580e-02
## ASV6100     -1.332949e-02 -1.389007e-02 -1.447268e-02 -1.507812e-02
## ASV11359    -2.655959e-02 -2.755682e-02 -2.858254e-02 -2.963697e-02
## ASV6604      4.150858e-03  4.325591e-03  4.506404e-03  4.693382e-03
## ASV5004     -9.389162e-03 -9.751061e-03 -1.012513e-02 -1.051173e-02
## ASV1483     -3.871202e-03 -4.009173e-03 -4.150718e-03 -4.295854e-03
## ASV9773     -1.247743e-02 -1.298061e-02 -1.350181e-02 -1.404160e-02
## ASV4059      2.267514e-03  2.440050e-03  2.622575e-03  2.815391e-03
## ASV1193      1.386767e-02  1.437568e-02  1.489838e-02  1.543602e-02
## ASV4610      3.654001e-04  4.609403e-04  5.624340e-04  6.699279e-04
## ASV0742      9.848229e-04  1.102813e-03  1.228051e-03  1.360700e-03
## ASV1502     -2.218146e-03 -2.357632e-03 -2.504105e-03 -2.657746e-03
## ASV0195     -5.643930e-04 -6.186688e-04 -6.763631e-04 -7.376010e-04
## ASV1213      7.476514e-03  7.659908e-03  7.843315e-03  8.026506e-03
## ASV1648     -1.198388e-02 -1.249208e-02 -1.302083e-02 -1.357095e-02
## ASV6984     -1.132703e-02 -1.181359e-02 -1.232029e-02 -1.284795e-02
## ASV0396      2.693387e-04  2.978010e-04  3.267223e-04  3.559097e-04
## ASV4297      1.159966e-02  1.192450e-02  1.225309e-02  1.258528e-02
## ASV2622      1.994722e-02  2.059948e-02  2.126615e-02  2.194728e-02
## ASV3512      1.250811e-02  1.315000e-02  1.382391e-02  1.453126e-02
## ASV2411      1.761842e-02  1.837009e-02  1.914976e-02  1.995814e-02
## ASV2291     -1.181544e-02 -1.246786e-02 -1.315257e-02 -1.387071e-02
## ASV0807      2.022282e-02  2.094181e-02  2.167912e-02  2.243482e-02
## ASV1292      3.362871e-03  3.429038e-03  3.494421e-03  3.558993e-03
## ASV1035      1.668999e-02  1.723439e-02  1.779169e-02  1.836209e-02
## ASV0070      1.321856e-03  1.419837e-03  1.523905e-03  1.634338e-03
## ASV0255      1.013075e-03  1.008929e-03  1.001113e-03  9.892761e-04
## ASV0057     -3.850706e-03 -3.937746e-03 -4.023857e-03 -4.108839e-03
## ASV0077     -4.381734e-04 -4.306784e-04 -4.219023e-04 -4.118293e-04
## ASV0625      9.026014e-03  9.286682e-03  9.550747e-03  9.818079e-03
## ASV2464      6.168104e-02  6.351800e-02  6.538515e-02  6.728209e-02
## ASV1315      2.333397e-02  2.434387e-02  2.539227e-02  2.648017e-02
## ASV2673      2.014815e-02  2.102770e-02  2.194158e-02  2.289080e-02
## ASV2161      8.542800e-03  8.923389e-03  9.319871e-03  9.732818e-03
## ASV0337     -4.381731e-03 -4.556299e-03 -4.736868e-03 -4.923594e-03
## ASV7680     -2.921950e-02 -3.040228e-02 -3.162626e-02 -3.289243e-02
## ASV0611      1.650409e-02  1.718731e-02  1.789589e-02  1.863061e-02
## ASV3118     -1.878179e-02 -1.960673e-02 -2.046380e-02 -2.135390e-02
## ASV1284     -1.921656e-03 -2.318135e-03 -2.748989e-03 -3.216262e-03
## ASV0889      1.059110e-02  1.096683e-02  1.135371e-02  1.175208e-02
## ASV4649     -5.867514e-03 -6.094920e-03 -6.329867e-03 -6.572549e-03
## ASV1108     -1.495479e-02 -1.565024e-02 -1.637539e-02 -1.713124e-02
## ASV0738      1.002509e-02  1.055437e-02  1.111031e-02  1.169406e-02
## ASV0473     -2.318305e-03 -2.431254e-03 -2.547766e-03 -2.667725e-03
## ASV0598     -5.817627e-03 -6.148514e-03 -6.497381e-03 -6.865050e-03
## ASV0429      6.984813e-03  7.181297e-03  7.379297e-03  7.578589e-03
## ASV1549      1.872064e-02  1.954054e-02  2.039226e-02  2.127665e-02
## ASV1203      1.146738e-02  1.185470e-02  1.225075e-02  1.265553e-02
## ASV4532      1.890567e-04  1.919405e-04  1.955085e-04  1.998997e-04
## ASV0274      2.781832e-03  2.900585e-03  3.022825e-03  3.148493e-03
## ASV0163     -7.901378e-03 -8.142506e-03 -8.388693e-03 -8.640040e-03
## ASV1298      7.843167e-04  8.221063e-04  8.633808e-04  9.085251e-04
## ASV9424     -2.344387e-02 -2.444025e-02 -2.547582e-02 -2.655192e-02
## ASV0412      1.947819e-02  2.012754e-02  2.079167e-02  2.147062e-02
## ASV0284      2.353972e-03  2.351802e-03  2.343415e-03  2.328306e-03
## ASV0620     -6.738530e-03 -7.083080e-03 -7.443730e-03 -7.821058e-03
## ASV0153     -2.475871e-02 -2.582727e-02 -2.693585e-02 -2.808542e-02
## ASV0498      7.758847e-03  8.046235e-03  8.340606e-03  8.641834e-03
## ASV0097      4.919383e-03  5.134992e-03  5.358972e-03  5.591544e-03
## ASV0104     -2.776417e-02 -2.872909e-02 -2.971712e-02 -3.072824e-02
## ASV1282      7.883414e-03  8.072136e-03  8.258198e-03  8.440939e-03
## ASV3883     -1.062380e-02 -1.111365e-02 -1.162277e-02 -1.215157e-02
## ASV0801      4.342262e-03  4.524499e-03  4.714192e-03  4.911681e-03
## ASV1611     -2.158889e-02 -2.251565e-02 -2.347810e-02 -2.447728e-02
## ASV0227     -5.659982e-03 -5.961617e-03 -6.277868e-03 -6.609276e-03
## ASV0833      6.664058e-03  6.921509e-03  7.186966e-03  7.460563e-03
## ASV0718      2.976120e-02  3.092344e-02  3.212339e-02  3.336179e-02
## ASV1139      7.662261e-04  6.729226e-04  5.689169e-04  4.536037e-04
## ASV0766     -5.318380e-03 -5.564209e-03 -5.819792e-03 -6.085358e-03
## ASV2091      1.883396e-02  1.936474e-02  1.990073e-02  2.044147e-02
## ASV1238     -2.444289e-02 -2.552846e-02 -2.666149e-02 -2.784403e-02
## ASV9193     -5.001312e-03 -5.321498e-03 -5.660876e-03 -6.020400e-03
## ASV0290      1.629095e-03  1.651271e-03  1.673296e-03  1.695299e-03
## ASV0231      7.554777e-03  7.794811e-03  8.038802e-03  8.286577e-03
## ASV0185      7.591521e-03  7.989435e-03  8.407126e-03  8.845418e-03
## ASV2330      7.404750e-03  7.598966e-03  7.794905e-03  7.992514e-03
## ASV3119     -6.671346e-03 -7.013189e-03 -7.371494e-03 -7.746917e-03
## ASV2368     -1.354478e-02 -1.418120e-02 -1.484699e-02 -1.554342e-02
## ASV0122     -4.937676e-03 -5.109793e-03 -5.286326e-03 -5.467318e-03
## ASV1044      1.558971e-02  1.626389e-02  1.696472e-02  1.769309e-02
## ASV0160     -4.425586e-03 -4.549942e-03 -4.676322e-03 -4.804780e-03
## ASV0326      1.492483e-03  1.543619e-03  1.595551e-03  1.648203e-03
## ASV1388      2.581599e-02  2.671069e-02  2.762702e-02  2.856503e-02
## ASV0792      1.745071e-02  1.798762e-02  1.853335e-02  1.908766e-02
## ASV0036     -7.368579e-03 -7.680359e-03 -8.003053e-03 -8.336834e-03
## ASV2125      1.896147e-02  1.963702e-02  2.032977e-02  2.103974e-02
## ASV1075     -4.084906e-04 -4.335747e-04 -4.605136e-04 -4.894494e-04
## ASV0390      1.268106e-02  1.326062e-02  1.386555e-02  1.449685e-02
## ASV3790     -1.599667e-02 -1.664579e-02 -1.731787e-02 -1.801351e-02
## ASV1535     -6.157059e-03 -6.461964e-03 -6.780421e-03 -7.112845e-03
## ASV0263      1.849663e-02  1.920143e-02  1.992806e-02  2.067692e-02
## ASV0675      3.041499e-02  3.168317e-02  3.299775e-02  3.435997e-02
## ASV3348      2.877350e-03  3.009622e-03  3.147120e-03  3.289961e-03
## ASV0058     -7.534892e-03 -7.790787e-03 -8.052416e-03 -8.319743e-03
## ASV4142      9.537575e-03  9.823081e-03  1.011322e-02  1.040794e-02
## ASV0059     -5.889250e-03 -6.081436e-03 -6.277402e-03 -6.477089e-03
## ASV0013     -1.163142e-02 -1.206650e-02 -1.251448e-02 -1.297554e-02
## ASV0033     -6.360987e-03 -6.629928e-03 -6.908413e-03 -7.196621e-03
## ASV4354     -7.193281e-03 -7.485939e-03 -7.789411e-03 -8.104018e-03
## ASV0022     -5.384770e-03 -5.614208e-03 -5.852017e-03 -6.098376e-03
## ASV0134     -5.861021e-03 -6.145134e-03 -6.442604e-03 -6.754021e-03
## ASV0415      1.180183e-03  1.236728e-03  1.295288e-03  1.355879e-03
## ASV10103    -2.889640e-02 -3.010587e-02 -3.135981e-02 -3.265941e-02
## ASV1613      1.636539e-02  1.684860e-02  1.733706e-02  1.783024e-02
## ASV0135     -1.780232e-03 -1.818981e-03 -1.857170e-03 -1.894704e-03
## ASV0469     -2.321997e-02 -2.403995e-02 -2.488291e-02 -2.574930e-02
## ASV0471      1.511317e-02  1.568323e-02  1.627140e-02  1.687813e-02
## ASV0451     -4.457787e-03 -4.701925e-03 -4.957836e-03 -5.225894e-03
## ASV0747      8.918074e-03  9.258116e-03  9.608088e-03  9.968061e-03
## ASV1314     -1.065229e-02 -1.114413e-02 -1.165763e-02 -1.219363e-02
## ASV0425     -2.591871e-02 -2.670533e-02 -2.750528e-02 -2.831841e-02
## ASV0559     -7.859834e-03 -8.185397e-03 -8.524497e-03 -8.877742e-03
## ASV0148     -2.337438e-04 -1.769614e-04 -1.138719e-04 -4.407155e-05
## ASV0129      4.640373e-03  4.939854e-03  5.257054e-03  5.592815e-03
## ASV1072      1.033621e-03  1.026878e-03  1.016756e-03  1.003011e-03
## ASV2390      1.165299e-02  1.191303e-02  1.216913e-02  1.242057e-02
## ASV0548      1.014110e-02  1.050597e-02  1.088051e-02  1.126478e-02
## ASV0168     -4.891404e-03 -5.057782e-03 -5.228251e-03 -5.402851e-03
## ASV0066     -5.559554e-03 -5.743461e-03 -5.930828e-03 -6.121546e-03
## ASV0468     -3.349357e-03 -3.484274e-03 -3.624165e-03 -3.769206e-03
## ASV0172     -9.160528e-04 -9.120089e-04 -9.052263e-04 -8.954986e-04
## ASV0236      3.060907e-03  3.313852e-03  3.583027e-03  3.869143e-03
## ASV0250      1.184544e-02  1.243946e-02  1.306213e-02  1.371465e-02
## ASV0338      4.478920e-03  4.652237e-03  4.830064e-03  5.012339e-03
## ASV0450     -1.534090e-03 -1.625446e-03 -1.721904e-03 -1.823701e-03
## ASV0377      6.922479e-03  7.151868e-03  7.385670e-03  7.623755e-03
## ASV1022     -1.916466e-05 -1.533671e-07  2.138907e-05  4.569125e-05
## ASV6174     -6.376642e-04 -6.817388e-04 -7.281425e-04 -7.768888e-04
## ASV0786     -2.284666e-03 -2.411856e-03 -2.544670e-03 -2.683199e-03
## ASV0053     -8.305493e-03 -8.620584e-03 -8.945145e-03 -9.279313e-03
## ASV0697     -4.366067e-03 -4.511024e-03 -4.659658e-03 -4.812057e-03
## ASV0785      9.691219e-03  1.002363e-02  1.036413e-02  1.071279e-02
## ASV1967     -9.538770e-03 -9.870295e-03 -1.021053e-02 -1.055956e-02
## ASV0385      4.104421e-03  4.273742e-03  4.448180e-03  4.627710e-03
## ASV0295      1.741561e-03  1.855873e-03  1.977010e-03  2.105300e-03
## ASV0072     -6.956031e-03 -7.162974e-03 -7.372122e-03 -7.583236e-03
## ASV0157      7.001078e-04  8.053093e-04  9.194342e-04  1.043024e-03
## ASV0501      1.811315e-02  1.879867e-02  1.950367e-02  2.022822e-02
## ASV10729    -2.371266e-02 -2.466683e-02 -2.565381e-02 -2.667437e-02
## ASV1470      8.220290e-03  8.401240e-03  8.579147e-03  8.753437e-03
## ASV0050     -1.785058e-02 -1.846149e-02 -1.908641e-02 -1.972530e-02
## ASV0411     -5.001773e-03 -5.220960e-03 -5.449174e-03 -5.686763e-03
## ASV0549      7.612881e-03  7.924526e-03  8.246993e-03  8.580514e-03
## ASV0184      2.326318e-03  2.419714e-03  2.516847e-03  2.617892e-03
## ASV0705      3.892018e-03  4.004280e-03  4.117255e-03  4.230752e-03
## ASV1715      9.834525e-03  1.020635e-02  1.058929e-02  1.098351e-02
## ASV0603      1.928223e-03  2.027005e-03  2.131335e-03  2.241544e-03
## ASV0826      1.584915e-02  1.642492e-02  1.701710e-02  1.762597e-02
## ASV0034     -4.608240e-03 -4.753098e-03 -4.900381e-03 -5.050012e-03
## ASV0838     -6.104580e-04 -8.395699e-04 -1.091936e-03 -1.369217e-03
## ASV0614     -4.316032e-03 -4.471664e-03 -4.631606e-03 -4.795918e-03
## ASV0014     -1.160061e-02 -1.202112e-02 -1.245304e-02 -1.289647e-02
## ASV0585     -1.404992e-03 -1.563148e-03 -1.731934e-03 -1.911717e-03
## ASV0016     -1.213242e-02 -1.257283e-02 -1.302526e-02 -1.348981e-02
## ASV5394     -9.612933e-03 -9.981266e-03 -1.036055e-02 -1.075087e-02
## ASV0666      1.737625e-02  1.791177e-02  1.845631e-02  1.900971e-02
## ASV2085      1.599242e-04 -1.450475e-05 -2.054886e-04 -4.139297e-04
## ASV0003     -8.255686e-03 -8.554974e-03 -8.862442e-03 -9.178169e-03
## ASV0346      4.932426e-03  5.137052e-03  5.348315e-03  5.566267e-03
## ASV0267      8.150151e-04  8.735230e-04  9.346230e-04  9.982670e-04
## ASV0353      7.673946e-03  7.998822e-03  8.335767e-03  8.685099e-03
## ASV2419      1.717137e-02  1.776893e-02  1.838091e-02  1.900726e-02
## ASV0447      1.128620e-02  1.176203e-02  1.225532e-02  1.276650e-02
## ASV0654      1.439407e-02  1.491371e-02  1.544698e-02  1.599393e-02
## ASV0151      3.099763e-03  3.264517e-03  3.437315e-03  3.618443e-03
## ASV0065     -5.351650e-03 -5.537542e-03 -5.727997e-03 -5.923032e-03
## ASV0527      1.355404e-02  1.404238e-02  1.454382e-02  1.505847e-02
## ASV4055     -3.265049e-03 -3.446839e-03 -3.639519e-03 -3.843771e-03
## ASV0166     -6.010523e-03 -6.194670e-03 -6.381819e-03 -6.571907e-03
## ASV0417     -1.914149e-03 -1.947120e-03 -1.978680e-03 -2.008690e-03
## ASV0078     -3.580182e-03 -3.685256e-03 -3.791124e-03 -3.897615e-03
## ASV0322      5.459923e-04  6.373520e-04  7.372600e-04  8.462766e-04
## ASV0156     -1.072685e-02 -1.116918e-02 -1.162790e-02 -1.210355e-02
## ASV0648     -2.353814e-02 -2.450509e-02 -2.550629e-02 -2.654255e-02
## ASV0407     -2.022139e-03 -2.118090e-03 -2.218515e-03 -2.323607e-03
## ASV2030     -3.811296e-03 -3.987655e-03 -4.173216e-03 -4.368497e-03
## ASV0300      3.044384e-03  3.176103e-03  3.312666e-03  3.454174e-03
## ASV1150      8.959902e-04  9.398542e-04  9.853717e-04  1.032546e-03
## ASV0958      9.807410e-03  1.026156e-02  1.073567e-02  1.123051e-02
## ASV0216     -8.480065e-03 -8.804639e-03 -9.141095e-03 -9.489934e-03
## ASV0446      1.435320e-02  1.492982e-02  1.552555e-02  1.614072e-02
## ASV0367     -9.043622e-03 -9.397695e-03 -9.763306e-03 -1.014069e-02
## ASV0200     -5.281280e-03 -5.480769e-03 -5.685929e-03 -5.896783e-03
## ASV0334     -1.481375e-03 -1.495893e-03 -1.509448e-03 -1.522080e-03
## ASV1311      2.041401e-03  2.059528e-03  2.074221e-03  2.085181e-03
## ASV0458      2.928641e-03  2.958901e-03  2.985356e-03  3.007713e-03
## ASV1371      1.042402e-03  1.085342e-03  1.129290e-03  1.174187e-03
## ASV0418      9.714110e-03  1.001018e-02  1.031119e-02  1.061705e-02
## ASV0004      1.353283e-03  1.391907e-03  1.430982e-03  1.470484e-03
## ASV1943      1.874953e-02  1.903029e-02  1.929918e-02  1.955535e-02
## ASV1495     -5.058139e-03 -5.368445e-03 -5.696383e-03 -6.042754e-03
## ASV0901     -1.115549e-02 -1.164240e-02 -1.214935e-02 -1.267707e-02
## ASV0628      3.644674e-03  3.714408e-03  3.781619e-03  3.845972e-03
## ASV0400      2.608886e-03  2.677608e-03  2.745846e-03  2.813370e-03
## ASV0116     -3.227842e-03 -3.365436e-03 -3.508369e-03 -3.656811e-03
## ASV0788      2.891115e-02  3.016232e-02  3.146374e-02  3.281716e-02
## ASV0117      2.357664e-03  2.465873e-03  2.578551e-03  2.695833e-03
## ASV3137     -5.051903e-04 -5.192532e-04 -5.332536e-04 -5.471360e-04
## ASV0001      1.409507e-03  1.447422e-03  1.485615e-03  1.524057e-03
## ASV1651      4.252264e-03  4.379703e-03  4.509250e-03  4.640893e-03
## ASV1692      2.370984e-02  2.471369e-02  2.575582e-02  2.683741e-02
## ASV0660      4.811040e-03  4.869345e-03  4.920808e-03  4.964780e-03
## ASV0508      2.201987e-04  2.218101e-04  2.229422e-04  2.235363e-04
## ASV1660     -5.698324e-03 -5.962886e-03 -6.237845e-03 -6.523414e-03
## ASV0233      6.725823e-03  6.986942e-03  7.256504e-03  7.534691e-03
## ASV1343     -1.338947e-02 -1.395551e-02 -1.454338e-02 -1.515380e-02
## ASV0209      4.741235e-03  4.867888e-03  4.995033e-03  5.122481e-03
## ASV0193     -5.689393e-03 -5.844334e-03 -5.999763e-03 -6.155413e-03
## ASV0357      4.398278e-03  4.645777e-03  4.907079e-03  5.182879e-03
## ASV0198      4.994749e-03  5.173400e-03  5.357316e-03  5.546630e-03
## ASV0007      1.143863e-03  1.169659e-03  1.195245e-03  1.220581e-03
## ASV1772     -9.207112e-04 -8.689061e-04 -8.071317e-04 -7.343904e-04
## ASV0009      8.575611e-04  8.723868e-04  8.866854e-04  9.004144e-04
## ASV0006     -1.768275e-03 -1.848327e-03 -1.931616e-03 -2.018231e-03
## ASV0011     -5.371202e-03 -5.590043e-03 -5.816612e-03 -6.051104e-03
## ASV0015      6.267221e-04  6.356106e-04  6.438502e-04  6.513815e-04
## ASV0017      7.316730e-04  7.443681e-04  7.565788e-04  7.682566e-04
## ASV0235     -5.061503e-03 -5.271714e-03 -5.489707e-03 -5.715722e-03
## ASV0382      3.660243e-03  3.784649e-03  3.910432e-03  4.037311e-03
## ASV2357      1.622018e-02  1.688862e-02  1.758160e-02  1.829982e-02
## ASV0567     -3.425084e-03 -3.584980e-03 -3.752566e-03 -3.928222e-03
## ASV0165      2.641058e-03  2.744467e-03  2.851104e-03  2.961014e-03
## ASV0005      3.495279e-03  3.619073e-03  3.745913e-03  3.875794e-03
## ASV0384      4.899208e-04  5.492868e-04  6.135215e-04  6.829306e-04
## ASV0002      5.928594e-04  6.127410e-04  6.331436e-04  6.540771e-04
## ASV3017      1.583802e-02  1.629531e-02  1.675764e-02  1.722464e-02
## ASV0091     -5.077104e-04 -5.315604e-04 -5.568183e-04 -5.835918e-04
## ASV0186     -7.189236e-03 -7.447258e-03 -7.711564e-03 -7.982100e-03
## ASV0370      3.559024e-03  3.680204e-03  3.804424e-03  3.931737e-03
## ASV0018      4.555503e-03  4.720687e-03  4.890256e-03  5.064232e-03
## ASV1377      4.024213e-02  4.149556e-02  4.277034e-02  4.406597e-02
## ASV0019      4.811325e-03  4.987421e-03  5.168335e-03  5.354104e-03
## ASV0023     -3.359983e-03 -3.497389e-03 -3.639433e-03 -3.786190e-03
## ASV2194      5.859392e-03  6.125573e-03  6.403234e-03  6.692807e-03
## ASV1155      1.730783e-02  1.790286e-02  1.851433e-02  1.914261e-02
## ASV0510     -3.614965e-03 -3.696824e-03 -3.779110e-03 -3.861870e-03
## ASV2371     -1.027702e-02 -1.061337e-02 -1.095694e-02 -1.130768e-02
## ASV0024     -4.145237e-03 -4.313685e-03 -4.487800e-03 -4.667683e-03
## ASV2452      8.465515e-03  8.646424e-03  8.824190e-03  8.998335e-03
## ASV2332     -3.100915e-02 -3.210295e-02 -3.322742e-02 -3.438310e-02
## ASV2591      1.197251e-02  1.250540e-02  1.305638e-02  1.362557e-02
## ASV0521      8.484841e-03  8.837399e-03  9.202871e-03  9.581613e-03
## ASV5542      7.924453e-03  8.237901e-03  8.561630e-03  8.895871e-03
## ASV0336     -1.855888e-03 -1.961945e-03 -2.073511e-03 -2.190824e-03
## ASV10102     1.467717e-02  1.526089e-02  1.586332e-02  1.648472e-02
## ASV16823    -1.675210e-02 -1.724195e-02 -1.773971e-02 -1.824528e-02
## ASV3104      8.667809e-02  8.921252e-02  9.178784e-02  9.440355e-02
## ASV0781      1.502325e-02  1.558714e-02  1.616885e-02  1.676883e-02
## ASV10899     1.332266e-02  1.400285e-02  1.471528e-02  1.546121e-02
## ASV11222    -2.948531e-02 -3.034739e-02 -3.122337e-02 -3.211308e-02
## ASV11327    -2.647230e-02 -2.724625e-02 -2.803268e-02 -2.883142e-02
## ASV12458    -2.948466e-02 -3.034663e-02 -3.122250e-02 -3.211207e-02
## ASV1636      1.869327e-02  1.931092e-02  1.994254e-02  2.058820e-02
## ASV1890     -1.160167e-02 -1.187256e-02 -1.214485e-02 -1.241851e-02
## ASV2898      2.518972e-02  2.602742e-02  2.688432e-02  2.776054e-02
## ASV8328      1.026409e-02  1.092743e-02  1.162836e-02  1.236849e-02
## ASV0709     -2.947809e-02 -3.050128e-02 -3.154939e-02 -3.262251e-02
## ASV0856      3.000500e-02  3.128507e-02  3.261224e-02  3.398762e-02
## ASV0909      1.309538e-02  1.381213e-02  1.456418e-02  1.535279e-02
## ASV0937     -2.052998e-02 -2.142064e-02 -2.234817e-02 -2.331399e-02
## ASV11390    -4.208016e-02 -4.331019e-02 -4.456002e-02 -4.582938e-02
## ASV11966     1.563303e-02  1.632143e-02  1.703548e-02  1.777575e-02
## ASV12990     7.871916e-03  8.115151e-03  8.363084e-03  8.615747e-03
## ASV14797     1.133425e-02  1.167676e-02  1.202549e-02  1.238045e-02
## ASV14904    -6.038325e-02 -6.214818e-02 -6.394149e-02 -6.576281e-02
## ASV15304     1.094546e-02  1.145892e-02  1.199283e-02  1.254767e-02
## ASV16696    -2.086334e-02 -2.147312e-02 -2.209270e-02 -2.272196e-02
## ASV1690      5.001295e-02  5.204994e-02  5.415153e-02  5.631831e-02
## ASV2029      2.904423e-02  3.007819e-02  3.114058e-02  3.223182e-02
## ASV2834      4.028740e-02  4.185273e-02  4.346621e-02  4.512847e-02
## ASV4003      4.103131e-02  4.301411e-02  4.509062e-02  4.726501e-02
## ASV4064      1.962119e-02  2.040459e-02  2.121404e-02  2.205012e-02
## ASV4294      1.574121e-02  1.653025e-02  1.735633e-02  1.822088e-02
## ASV4609      9.828633e-03  1.018677e-02  1.055643e-02  1.093798e-02
## ASV6283     -1.950248e-02 -2.007245e-02 -2.065157e-02 -2.123974e-02
## ASV6491     -2.795289e-02 -2.876981e-02 -2.959985e-02 -3.044284e-02
## ASV7453      2.119967e-02  2.215020e-02  2.313727e-02  2.416174e-02
## ASV7959      1.022642e-02  1.077604e-02  1.135279e-02  1.195776e-02
## ASV8219      2.415715e-01  2.486311e-01  2.558041e-01  2.630890e-01
## ASV8547     -2.502604e-02 -2.575738e-02 -2.650047e-02 -2.725515e-02
## ASV9319      1.574298e-02  1.642900e-02  1.714271e-02  1.788506e-02
## ASV9382     -4.896663e-02 -5.039757e-02 -5.185149e-02 -5.332809e-02
## ASV11516    -3.270565e-02 -3.366139e-02 -3.463248e-02 -3.561872e-02
## ASV14377    -2.361517e-02 -2.430526e-02 -2.500643e-02 -2.571854e-02
## ASV1867      2.481812e-02  2.583289e-02  2.688390e-02  2.797217e-02
## ASV1895      7.988405e-03  8.131300e-03  8.267907e-03  8.397529e-03
## ASV3168      1.160354e-02  1.191957e-02  1.223785e-02  1.255808e-02
## ASV4449      7.970331e-02  8.277395e-02  8.594720e-02  8.922580e-02
## ASV6596      2.226349e-02  2.335068e-02  2.448804e-02  2.567751e-02
## ASV7492      1.797232e-03  2.043683e-03  2.307734e-03  2.590144e-03
## ASV9854     -4.847477e-03 -4.983793e-03 -5.121978e-03 -5.261969e-03
## ASV6296      3.962769e-01  4.078569e-01  4.196230e-01  4.315727e-01
## ASV4201      7.858222e-03  8.380725e-03  8.934173e-03  9.520050e-03
## ASV0552      1.677029e-02  1.743173e-02  1.811419e-02  1.881799e-02
## ASV3671     -1.066560e-02 -1.110999e-02 -1.157371e-02 -1.205771e-02
## ASV3529      6.524683e-04  7.815669e-04  9.186209e-04  1.063762e-03
## ASV1060      5.222361e-03  5.471374e-03  5.732273e-03  6.005613e-03
## ASV0239     -4.168023e-03 -4.268291e-03 -4.368463e-03 -4.468399e-03
## ASV5711     -2.390858e-02 -2.475335e-02 -2.562136e-02 -2.651294e-02
## ASV4152     -3.728405e-02 -3.871973e-02 -4.019996e-02 -4.172539e-02
## ASV1461      1.383041e-02  1.417693e-02  1.452426e-02  1.487203e-02
## ASV2877      7.435720e-03  7.627275e-03  7.818951e-03  8.010431e-03
## ASV0012      1.661693e-03  1.725515e-03  1.791399e-03  1.859393e-03
## ASV9823      2.722098e-04  1.847454e-04  8.746559e-05 -2.026936e-05
## ASV0008      1.736976e-03  1.802628e-03  1.870368e-03  1.940244e-03
## ASV7832     -2.285426e-02 -2.378421e-02 -2.474711e-02 -2.574378e-02
## ASV1915     -2.668999e-03 -2.782297e-03 -2.900855e-03 -3.024936e-03
## ASV0055     -2.717751e-03 -2.854870e-03 -2.998460e-03 -3.148770e-03
## ASV0032      4.271408e-04  4.272375e-04  4.266196e-04  4.252774e-04
## ASV2977     -3.041778e-02 -3.156402e-02 -3.274388e-02 -3.395769e-02
## ASV0466      1.835215e-02  1.880587e-02  1.925905e-02  1.971099e-02
## ASV3866      1.869730e-02  1.949845e-02  2.033133e-02  2.119704e-02
## ASV0040      6.277456e-03  6.525022e-03  6.780772e-03  7.044876e-03
## ASV0496     -3.982642e-03 -4.233954e-03 -4.498812e-03 -4.777698e-03
## ASV0052      5.300121e-03  5.510860e-03  5.728811e-03  5.954164e-03
## ASV3828     -1.389285e-02 -1.429109e-02 -1.469511e-02 -1.510478e-02
## ASV1930      7.520522e-03  7.735489e-03  7.952389e-03  8.171021e-03
## ASV2126      1.457933e-02  1.510410e-02  1.564404e-02  1.619948e-02
## ASV0793      2.057484e-02  2.141967e-02  2.229456e-02  2.320032e-02
## ASV0299     -8.283444e-04 -8.949004e-04 -9.672084e-04 -1.045726e-03
## ASV0208      1.431057e-02  1.488687e-02  1.548387e-02  1.610219e-02
## ASV0511     -3.977641e-03 -4.070159e-03 -4.163004e-03 -4.256187e-03
## ASV1123     -1.286248e-02 -1.319552e-02 -1.352995e-02 -1.386536e-02
## ASV0099      9.466040e-04  1.005014e-03  1.066998e-03  1.132745e-03
## ASV0752     -1.150563e-02 -1.201510e-02 -1.254517e-02 -1.309652e-02
## ASV0883      1.538914e-02  1.604476e-02  1.672402e-02  1.742738e-02
## ASV0683      1.958507e-02  2.041392e-02  2.127373e-02  2.216536e-02
## ASV4117     -2.932595e-02 -3.052201e-02 -3.176180e-02 -3.304661e-02
## ASV2172      5.950222e-04  5.634797e-04  5.271287e-04  4.856240e-04
## ASV0330     -5.621224e-03 -5.855112e-03 -6.097889e-03 -6.349856e-03
## ASV0728      2.513511e-02  2.605943e-02  2.701037e-02  2.798835e-02
## ASV0499      7.793237e-03  8.131174e-03  8.482312e-03  8.847048e-03
## ASV0120     -1.118251e-02 -1.158903e-02 -1.200621e-02 -1.243405e-02
## ASV1446      4.296611e-03  4.278646e-03  4.248279e-03  4.204558e-03
## ASV17171    -2.232681e-02 -2.321307e-02 -2.413115e-02 -2.508201e-02
## ASV0533      2.161973e-03  2.264818e-03  2.372067e-03  2.483855e-03
## ASV2495     -8.292882e-03 -8.733485e-03 -9.195612e-03 -9.680021e-03
## ASV5582      6.222547e-03  6.305524e-03  6.381979e-03  6.451315e-03
## ASV1488      3.098384e-03  3.174132e-03  3.248759e-03  3.321978e-03
## ASV0682      5.753264e-03  6.002848e-03  6.261920e-03  6.530724e-03
## ASV0068     -8.621216e-03 -8.938736e-03 -9.264559e-03 -9.598654e-03
## ASV1987     -2.561921e-02 -2.675541e-02 -2.793666e-02 -2.916425e-02
## ASV0035     -3.565705e-03 -3.797330e-03 -4.043597e-03 -4.305329e-03
## ASV7192     -1.217581e-02 -1.258773e-02 -1.300877e-02 -1.343881e-02
## ASV0873     -2.654552e-02 -2.839666e-02 -3.034510e-02 -3.239367e-02
## ASV4749     -5.639658e-03 -6.067008e-03 -6.520778e-03 -7.002121e-03
## ASV2174      5.952515e-03  6.041452e-03  6.124628e-03  6.201508e-03
## ASV1476     -1.131054e-02 -1.182230e-02 -1.235554e-02 -1.291098e-02
## ASV0740     -3.121978e-02 -3.259066e-02 -3.401720e-02 -3.550133e-02
## ASV0170     -5.437311e-03 -5.650898e-03 -5.871715e-03 -6.099950e-03
## ASV2466     -2.517775e-02 -2.619102e-02 -2.724031e-02 -2.832661e-02
## ASV1709      8.551096e-03  8.909217e-03  9.284589e-03  9.678303e-03
## ASV6170     -4.169542e-02 -4.344468e-02 -4.525894e-02 -4.714001e-02
## ASV3673      2.129321e-02  2.221532e-02  2.317311e-02  2.416759e-02
## ASV1745     -6.312199e-03 -6.614301e-03 -6.929661e-03 -7.258720e-03
##                                                                    
## (Intercept)  1.484760e-01  0.1538104716  1.592847e-01  0.1648995239
## ASV1236      2.519032e-02  0.0259807715  2.678741e-02  0.0276102272
## ASV0421      6.133845e-03  0.0064467090  6.772169e-03  0.0071104026
## ASV0691     -1.373141e-02 -0.0139637091 -1.419156e-02 -0.0144147367
## ASV0899      2.142403e-02  0.0220512719  2.268736e-02  0.0233320499
## ASV1004      5.040093e-02  0.0519523425  5.353242e-02  0.0551409777
## ASV1041     -1.910904e-02 -0.0195891416 -2.006815e-02 -0.0205452050
## ASV1058      3.154657e-02  0.0325341906  3.354203e-02  0.0345701416
## ASV12542     1.113917e-02  0.0114578608  1.178254e-02  0.0121133418
## ASV1294      2.961643e-02  0.0305587436  3.152190e-02  0.0325061265
## ASV13113     1.470413e-02  0.0153844491  1.609421e-02  0.0168344739
## ASV1318      2.917237e-02  0.0300758090  3.099694e-02  0.0319357796
## ASV2269     -4.893662e-02 -0.0503493299 -5.177974e-02 -0.0532269095
## ASV2542      3.194067e-02  0.0332543147  3.461590e-02  0.0360267732
## ASV2660     -1.919964e-02 -0.0197539701 -2.031630e-02 -0.0208864242
## ASV2737      5.695222e-03  0.0058398465  5.986759e-03  0.0061360645
## ASV2840      2.230302e-02  0.0228053824  2.330569e-02  0.0238033388
## ASV3053      1.269297e-01  0.1305590475  1.342489e-01  0.1379992159
## ASV3077      8.379820e-03  0.0086361464  8.898196e-03  0.0091660908
## ASV3134      2.209796e-02  0.0230793826  2.410131e-02  0.0251651546
## ASV3140      2.471118e-02  0.0256074042  2.652787e-02  0.0274727494
## ASV3579      1.223525e-02  0.0128139299  1.341654e-02  0.0140437079
## ASV6119     -1.338700e-02 -0.0137729528 -1.416372e-02 -0.0145590716
## ASV7557     -2.720342e-02 -0.0279876009 -2.878158e-02 -0.0295848799
## ASV8422      6.595956e-03  0.0067962285  7.001150e-03  0.0072108574
## ASV1086     -7.744638e-04 -0.0007953823 -8.172755e-04 -0.0008402390
## ASV1310      1.324483e-02  0.0136406496  1.404273e-02  0.0144509085
## ASV15750    -1.208815e-03 -0.0012173195 -1.223904e-03 -0.0012284326
## ASV16905    -5.593147e-03 -0.0057543855 -5.917657e-03 -0.0060828690
## ASV2033      3.253829e-02  0.0338543503  3.521440e-02  0.0366193100
## ASV2089      1.182483e-02  0.0121659033  1.251121e-02  0.0128605630
## ASV2127      3.940880e-02  0.0406258219  4.186652e-02  0.0431309055
## ASV2725      2.926700e-02  0.0300809225  3.090505e-02  0.0317390769
## ASV2804     -1.157828e-02 -0.0119121264 -1.225022e-02 -0.0125923682
## ASV3075      3.113833e-02  0.0323580359  3.362180e-02  0.0349310764
## ASV3327      4.549275e-02  0.0472698291  4.910388e-02  0.0509959881
## ASV3342      3.847535e-02  0.0399760188  4.152628e-02  0.0431273052
## ASV3532     -4.100249e-02 -0.0425813384 -4.421438e-02 -0.0459033595
## ASV3600      1.919990e-02  0.0199294433  2.068173e-02  0.0214571759
## ASV4013      3.197561e-02  0.0330379327  3.412378e-02  0.0352330688
## ASV4136      3.047939e-02  0.0313950651  3.232815e-02  0.0332786794
## ASV4195      1.181980e-01  0.1216076964  1.250611e-01  0.1285565104
## ASV4407     -4.567025e-02 -0.0469878973 -4.832250e-02 -0.0496733690
## ASV4717      6.280148e-03  0.0064265258  6.574980e-03  0.0067256632
## ASV6794      1.768942e-02  0.0182018073  1.872457e-02  0.0192579376
## ASV8324     -2.343513e-02 -0.0241115349 -2.479671e-02 -0.0254903095
## ASV8981      1.093198e-03  0.0012027514  1.319662e-03  0.0014442341
## ASV9859      1.526807e-02  0.0160702394  1.691329e-02  0.0177990772
## ASV0936      2.838079e-02  0.0294289165  3.050553e-02  0.0316107746
## ASV12683    -3.329034e-04 -0.0003438691 -3.541823e-04 -0.0003637150
## ASV1293      1.521001e-02  0.0156587416  1.611457e-02  0.0165773907
## ASV13055     8.031038e-04  0.0008800967  9.621315e-04  0.0010494144
## ASV17063    -1.216334e-02 -0.0125146626 -1.287058e-02 -0.0132309311
## ASV2228      9.920137e-03  0.0102067123  1.049704e-02  0.0107909900
## ASV2769      3.064106e-03  0.0032088295  3.358519e-03  0.0035131607
## ASV2803      9.296428e-03  0.0095283315  9.762407e-03  0.0099986296
## ASV2896      1.193523e-02  0.0124590570  1.300532e-02  0.0135749474
## ASV3062      1.627356e-02  0.0170049277  1.776438e-02  0.0185525475
## ASV3107      2.075743e-02  0.0215890155  2.244972e-02  0.0233402929
## ASV3265      2.144847e-02  0.0220683210  2.269721e-02  0.0233349310
## ASV3666     -1.248371e-04 -0.0001445145 -1.656929e-04 -0.0001884391
## ASV4497      7.867270e-03  0.0081173843  8.372736e-03  0.0086333316
## ASV6914     -2.218286e-03 -0.0023271070 -2.440348e-03 -0.0025581131
## ASV0576     -2.157767e-02 -0.0220676987 -2.255806e-02 -0.0230483992
## ASV0673      3.138157e-02  0.0324143682  3.347093e-02  0.0345514489
## ASV0772      1.544525e-02  0.0160007339  1.657274e-02  0.0171616520
## ASV0862      5.397633e-03  0.0057080208  6.031370e-03  0.0063678080
## ASV0898      1.435040e-02  0.0149282147  1.552458e-02  0.0161397687
## ASV0910      1.580744e-02  0.0164431139  1.710081e-02  0.0177810802
## ASV0964     -8.579197e-03 -0.0087878549 -8.997516e-03 -0.0092080634
## ASV10059     1.279414e-02  0.0133587264  1.394524e-02  0.0145542671
## ASV10263    -1.851936e-02 -0.0190551385 -1.959805e-02 -0.0201478347
## ASV1088      2.780145e-02  0.0289369380  3.011500e-02  0.0313370248
## ASV1101      2.621501e-02  0.0269727743  2.774137e-02  0.0285205387
## ASV1183      8.506414e-03  0.0088253806  9.154488e-03  0.0094940039
## ASV11956     5.639421e-03  0.0057778995  5.918198e-03  0.0060603919
## ASV12774    -9.183914e-04 -0.0009984124 -1.083065e-03 -0.0011724950
## ASV1321      4.197252e-02  0.0436809539  4.544750e-02  0.0472732355
## ASV13793    -1.277083e-02 -0.0131404125 -1.351491e-02 -0.0138941631
## ASV14482     6.719978e-04  0.0006975796  7.246637e-04  0.0007533503
## ASV15483     6.700129e-03  0.0069562618  7.220162e-03  0.0074919502
## ASV2062      2.737494e-02  0.0283160030  2.928177e-02  0.0302725970
## ASV2132      2.533153e-02  0.0262988297  2.729550e-02  0.0283219385
## ASV2413      1.994451e-02  0.0205903737  2.125150e-02  0.0219281174
## ASV2490      5.432468e-02  0.0558021849  5.729741e-02  0.0588098512
## ASV2594      9.471185e-03  0.0098671436  1.027912e-02  0.0107077386
## ASV2822     -3.369624e-02 -0.0346715910 -3.565995e-02 -0.0366608657
## ASV2863      3.555489e-02  0.0366191393  3.770303e-02  0.0388065587
## ASV2910      1.326614e-02  0.0136694234  1.408041e-02  0.0144991165
## ASV2980      1.632400e-02  0.0168742119  1.743764e-02  0.0180143904
## ASV3307      2.681788e-02  0.0275942060  2.838090e-02  0.0291775944
## ASV3474      2.495730e-02  0.0260027610  2.708551e-02  0.0282063577
## ASV3502      2.224945e-02  0.0230716608  2.391927e-02  0.0247929068
## ASV4236      2.452829e-02  0.0251430969  2.576168e-02  0.0263837092
## ASV4842     -3.120706e-03 -0.0031904946 -3.258030e-03 -0.0033229839
## ASV4894     -1.277342e-02 -0.0131432430 -1.351802e-02 -0.0138975692
## ASV5290      1.256788e-02  0.0130378885  1.352198e-02  0.0140204391
## ASV5501      8.060909e-03  0.0084058199  8.765769e-03  0.0091414275
## ASV5795      8.649264e-03  0.0089791922  9.319039e-03  0.0096689257
## ASV5987     -3.567650e-02 -0.0367095968 -3.775657e-02 -0.0388169423
## ASV6267     -4.020343e-02 -0.0413676795 -4.254759e-02 -0.0437426314
## ASV6862      1.539155e-02  0.0158349062  1.628596e-02  0.0167447474
## ASV7145      6.908143e-03  0.0071332082  7.365160e-03  0.0076042486
## ASV7673     -1.277479e-02 -0.0131448102 -1.351982e-02 -0.0138996593
## ASV7789      1.122360e-02  0.0117792328  1.236016e-02  0.0129672850
## ASV7809      2.043841e-03  0.0021686921  2.299438e-03  0.0024362061
## ASV8002     -1.613543e-02 -0.0166029199 -1.707676e-02 -0.0175567434
## ASV8205      8.450490e-03  0.0087769130  9.113929e-03  0.0094617488
## ASV9155     -3.598086e-03 -0.0036794046 -3.760155e-03 -0.0038402057
## ASV9221      4.840119e-03  0.0051279677  5.430960e-03  0.0057496884
## ASV9311     -2.588833e-02 -0.0266388393 -2.739964e-02 -0.0281704326
## ASV9557     -1.769448e-02 -0.0182075599 -1.872770e-02 -0.0192546926
## ASV9936     -3.568698e-02 -0.0367220076 -3.777133e-02 -0.0388345609
## ASV1445      2.677443e-02  0.0277792545  2.881409e-02  0.0298793860
## ASV4232      1.300954e-02  0.0136404320  1.430187e-02  0.0149952646
## ASV6479      7.465589e-03  0.0078974487  8.352077e-03  0.0088304071
## ASV0142     -1.524085e-02 -0.0156926748 -1.615237e-02 -0.0166198925
## ASV0378      1.024687e-02  0.0106793107  1.112626e-02  0.0115878774
## ASV1122      2.683056e-02  0.0278774397  2.895865e-02  0.0300749364
## ASV0123     -1.332822e-02 -0.0137168750 -1.411177e-02 -0.0145128390
## ASV2064      4.997470e-03  0.0050517312  5.099571e-03  0.0051404593
## ASV4459     -5.144598e-04 -0.0005245074 -5.357540e-04 -0.0005484135
## ASV0448      8.282273e-03  0.0086405877  9.012149e-03  0.0093972575
## ASV0397      1.412585e-02  0.0146148986  1.511626e-02  0.0156300360
## ASV0485      1.567501e-02  0.0161984169  1.673446e-02  0.0172832675
## ASV1566      2.397088e-02  0.0247956455  2.564106e-02  0.0265073019
## ASV1365      2.120619e-02  0.0219427838  2.269645e-02  0.0234670777
## ASV1065      3.047974e-02  0.0315805056  3.271176e-02  0.0338738705
## ASV0722     -2.101532e-03 -0.0022068825 -2.317718e-03 -0.0024343111
## ASV12660    -1.420277e-02 -0.0146072949 -1.501761e-02 -0.0154335954
## ASV0223      4.497381e-03  0.0046578863  4.823259e-03  0.0049936382
## ASV0229      7.889415e-03  0.0082072812  8.536584e-03  0.0088776795
## ASV0877      9.241289e-04  0.0008477918  7.600643e-04  0.0006600552
## ASV0983      1.491784e-02  0.0153823671  1.585544e-02  0.0163369470
## ASV0626      4.216090e-03  0.0044427699  4.679011e-03  0.0049250059
## ASV4146     -1.066674e-04 -0.0001807028 -2.640432e-04 -0.0003574755
## ASV4175     -2.195806e-02 -0.0227858032 -2.363799e-02 -0.0245149180
## ASV2082     -1.630060e-02 -0.0171803411 -1.810388e-02 -0.0190728872
## ASV2272      1.057762e-02  0.0109960519  1.142908e-02  0.0118770904
## ASV2245     -1.601328e-02 -0.0166262934 -1.725779e-02 -0.0179079928
## ASV0590     -1.665689e-02 -0.0175708569 -1.853037e-02 -0.0195371514
## ASV0217      4.534273e-03  0.0048270475  5.134799e-03  0.0054580065
## ASV0416      6.545805e-03  0.0066094700  6.665105e-03  0.0067121621
## ASV1056      1.637540e-02  0.0170307801  1.770718e-02  0.0184048862
## ASV7777     -2.144608e-02 -0.0222904396 -2.316534e-02 -0.0240718872
## ASV0455      3.531898e-03  0.0036499694  3.770294e-03  0.0038927999
## ASV0604      1.132351e-02  0.0117975749  1.228838e-02  0.0127962865
## ASV6100     -1.570726e-02 -0.0163609635 -1.704015e-02 -0.0177457640
## ASV11359    -3.072030e-02 -0.0318326972 -3.297426e-02 -0.0341450470
## ASV6604      4.886601e-03  0.0050861206  5.291989e-03  0.0055042356
## ASV5004     -1.091122e-02 -0.0113240019 -1.175046e-02 -0.0121909953
## ASV1483     -4.444592e-03 -0.0045969353 -4.752884e-03 -0.0049124275
## ASV9773     -1.460051e-02 -0.0151791328 -1.577805e-02 -0.0163978583
## ASV4059      3.018785e-03  0.0032330234  3.458352e-03  0.0036949929
## ASV1193      1.598881e-02  0.0165569965  1.714078e-02  0.0177403864
## ASV4610      7.834432e-04  0.0009029739  1.028486e-03  0.0011599171
## ASV0742      1.500906e-03  0.0016487962  1.804481e-03  0.0019680503
## ASV1502     -2.818725e-03 -0.0029872067 -3.163339e-03 -0.0033472601
## ASV0195     -8.025068e-04 -0.0008712038 -9.438147e-04 -0.0010204608
## ASV1213      8.209246e-03  0.0083912972  8.572421e-03  0.0087523759
## ASV1648     -1.414329e-02 -0.0147387358 -1.535820e-02 -0.0160026248
## ASV6984     -1.339744e-02 -0.0139696322 -1.456545e-02 -0.0151858411
## ASV0396      3.851419e-04  0.0004141680  4.427047e-04  0.0004704349
## ASV4297      1.292094e-02  0.0132599471  1.360217e-02  0.0139475076
## ASV2622      2.264292e-02  0.0233530966  2.407786e-02  0.0248172483
## ASV3512      1.527351e-02  0.0160521653  1.686878e-02  0.0177249404
## ASV2411      2.079588e-02  0.0216636572  2.256210e-02  0.0234918342
## ASV2291     -1.462342e-02 -0.0154118316 -1.623707e-02 -0.0171002643
## ASV0807      2.320899e-02  0.0240016831  2.481294e-02  0.0256427908
## ASV1292      3.622743e-03  0.0036856785  3.747826e-03  0.0038092345
## ASV1035      1.894579e-02  0.0195430319  2.015403e-02  0.0207790335
## ASV0070      1.751419e-03  0.0018754343  2.006675e-03  0.0021454352
## ASV0255      9.730472e-04  0.0009520344  9.258245e-04  0.0008939827
## ASV0057     -4.192487e-03 -0.0042745913 -4.354935e-03 -0.0044332982
## ASV0077     -4.004529e-04 -0.0003877769 -3.738166e-04 -0.0003586002
## ASV0625      1.008855e-02  0.0103620234  1.063837e-02  0.0109174542
## ASV2464      6.920839e-02  0.0711636223  7.314733e-02  0.0751590798
## ASV1315      2.760857e-02  0.0287784387  2.999074e-02  0.0312464238
## ASV2673      2.387635e-02  0.0248992351  2.596045e-02  0.0270610082
## ASV2161      1.016281e-02  0.0106104531  1.107635e-02  0.0115611081
## ASV0337     -5.116637e-03 -0.0053161567 -5.522316e-03 -0.0057352789
## ASV7680     -3.420179e-02 -0.0355553281 -3.695401e-02 -0.0383987875
## ASV0611      1.939225e-02  0.0201816125  2.099950e-02  0.0218467432
## ASV3118     -2.227794e-02 -0.0232368159 -2.423141e-02 -0.0252626217
## ASV1284     -3.722072e-03 -0.0042686183 -4.858178e-03 -0.0054931092
## ASV0889      1.216227e-02  0.0125846535  1.301960e-02  0.0134675327
## ASV4649     -6.823163e-03 -0.0070819054 -7.348978e-03 -0.0076245827
## ASV1108     -1.791877e-02 -0.0187389774 -1.959287e-02 -0.0204814486
## ASV0738      1.230682e-02  0.0129498101  1.362431e-02  0.0143316140
## ASV0473     -2.790988e-03 -0.0029173755 -3.046675e-03 -0.0031786359
## ASV0598     -7.252364e-03 -0.0076601877 -8.089404e-03 -0.0085409154
## ASV0429      7.778939e-03  0.0079801061  8.181839e-03  0.0083838831
## ASV1549      2.219454e-02  0.0231467573  2.413410e-02  0.0251573448
## ASV1203      1.306898e-02  0.0134910603  1.392170e-02  0.0143608260
## ASV4532      2.052691e-04  0.0002117878  2.196449e-04  0.0002290480
## ASV0274      3.277511e-03  0.0034097824  3.545191e-03  0.0036835978
## ASV0163     -8.896661e-03 -0.0091586819 -9.426244e-03 -0.0096995011
## ASV1298      9.579556e-04  0.0010121213  1.071505e-03  0.0011366222
## ASV9424     -2.766997e-02 -0.0288313893 -3.003766e-02 -0.0312902862
## ASV0412      2.216441e-02  0.0228730795  2.359664e-02  0.0243350914
## ASV0284      2.305950e-03  0.0022757964  2.237271e-03  0.0021897753
## ASV0620     -8.215649e-03 -0.0086280954 -9.058995e-03 -0.0095089498
## ASV0153     -2.927691e-02 -0.0305112452 -3.178930e-02 -0.0331119391
## ASV0498      8.949772e-03  0.0092642403  9.585035e-03  0.0099119212
## ASV0097      5.832928e-03  0.0060833371  6.342981e-03  0.0066120621
## ASV0104     -3.176238e-02 -0.0328194671 -3.389937e-02 -0.0350019499
## ASV1282      8.619657e-03  0.0087936145  8.962032e-03  0.0091240941
## ASV3883     -1.270045e-02 -0.0132697727 -1.385988e-02 -0.0144710930
## ASV0801      5.117330e-03  0.0053315209  5.554657e-03  0.0057871637
## ASV1611     -2.551425e-02 -0.0265900499 -2.770575e-02 -0.0288623938
## ASV0227     -6.956393e-03 -0.0073197739 -7.699984e-03 -0.0080975949
## ASV0833      7.742431e-03  0.0080326957  8.331482e-03  0.0086389120
## ASV0718      3.463940e-02  0.0359569144  3.731505e-02  0.0387145023
## ASV1139      3.263672e-04  0.0001865825  3.361721e-05 -0.0001331671
## ASV0766     -6.361124e-03 -0.0066472988 -6.944079e-03 -0.0072516490
## ASV2091      2.098652e-02  0.0215354046  2.208764e-02  0.0226427242
## ASV1238     -2.907823e-02 -0.0303663474 -3.171069e-02 -0.0331136766
## ASV9193     -6.401050e-03 -0.0068038313 -7.229777e-03 -0.0076799416
## ASV0290      1.717434e-03  0.0017398761  1.762824e-03  0.0017865025
## ASV0231      8.537941e-03  0.0087926825  9.050568e-03  0.0093113468
## ASV0185      9.305156e-03  0.0097872056  1.029245e-02  0.0108217908
## ASV2330      8.191747e-03  0.0083925729  8.594971e-03  0.0087989384
## ASV3119     -8.140127e-03 -0.0085518081 -8.982655e-03 -0.0094333762
## ASV2368     -1.627182e-02 -0.0170335284 -1.782995e-02 -0.0186625356
## ASV0122     -5.652809e-03 -0.0058428389 -6.037447e-03 -0.0062366742
## ASV1044      1.844988e-02  0.0192360227  2.005243e-02  0.0209000555
## ASV0160     -4.935378e-03 -0.0050681943 -5.203321e-03 -0.0053408666
## ASV0326      1.701491e-03  0.0017553205  1.809589e-03  0.0018641844
## ASV1388      2.952472e-02  0.0305060840  3.150909e-02  0.0325336758
## ASV0792      1.965033e-02  0.0202211172  2.079976e-02  0.0213860051
## ASV0036     -8.681863e-03 -0.0090382841 -9.406222e-03 -0.0097857836
## ASV2125      2.176692e-02  0.0225113165  2.327287e-02  0.0240515000
## ASV1075     -5.205323e-04 -0.0005539211 -5.897828e-04 -0.0006282929
## ASV0390      1.515555e-02  0.0158427046  1.655941e-02  0.0173067877
## ASV3790     -1.873332e-02 -0.0194779168 -2.024791e-02 -0.0210439125
## ASV1535     -7.459641e-03 -0.0078212096 -8.197942e-03 -0.0085902182
## ASV0263      2.144840e-02  0.0222428643  2.306068e-02  0.0239022017
## ASV0675      3.577106e-02  0.0372322465  3.874476e-02  0.0403098161
## ASV3348      3.438256e-03  0.0035921071  3.751613e-03  0.0039168628
## ASV0058     -8.592728e-03 -0.0088713218 -9.155466e-03 -0.0094450952
## ASV4142      1.070722e-02  0.0110110126  1.131930e-02  0.0116320654
## ASV0059     -6.680436e-03 -0.0068873745 -7.097832e-03 -0.0073117302
## ASV0013     -1.344987e-02 -0.0139376761 -1.443913e-02 -0.0149544117
## ASV0033     -7.494720e-03 -0.0078028668 -8.121208e-03 -0.0084498757
## ASV4354     -8.430082e-03 -0.0087679256 -9.117866e-03 -0.0094802185
## ASV0022     -6.353460e-03 -0.0066174359 -6.890463e-03 -0.0071726919
## ASV0134     -7.079996e-03 -0.0074211680 -7.778201e-03 -0.0081517872
## ASV0415      1.418515e-03  0.0014832055  1.549957e-03  0.0016187716
## ASV10103    -3.400581e-02 -0.0354001907 -3.684368e-02 -0.0383374067
## ASV1613      1.832760e-02  0.0188285526  1.933249e-02  0.0198387820
## ASV0135     -1.931482e-03 -0.0019674037 -2.002364e-03 -0.0020362587
## ASV0469     -2.663958e-02 -0.0275542331 -2.849373e-02 -0.0294585753
## ASV0471      1.750391e-02  0.0181492484  1.881467e-02  0.0195007255
## ASV0451     -5.506469e-03 -0.0057999247 -6.106618e-03 -0.0064268965
## ASV0747      1.033809e-02  0.0107182248  1.110848e-02  0.0115088681
## ASV1314     -1.275300e-02 -0.0133366150 -1.394538e-02 -0.0145802136
## ASV0425     -2.914454e-02 -0.0299835106 -3.083514e-02 -0.0316992740
## ASV0559     -9.245765e-03 -0.0096292221 -1.002880e-02 -0.0104452037
## ASV0148      3.285782e-05  0.0001173489  2.098489e-04  0.0003108192
## ASV0129      5.947999e-03  0.0063234860  6.720177e-03  0.0071389882
## ASV1072      9.853918e-04  0.0009636441  9.375085e-04  0.0009067223
## ASV2390      1.266661e-02  0.0129064754  1.313940e-02  0.0133645974
## ASV0548      1.165885e-02  0.0120627686  1.247657e-02  0.0129002872
## ASV0168     -5.581620e-03 -0.0057645966 -5.951819e-03 -0.0061433269
## ASV0066     -6.315488e-03 -0.0065125184 -6.712484e-03 -0.0069152193
## ASV0468     -3.919577e-03 -0.0040754689 -4.237077e-03 -0.0044046041
## ASV0172     -8.826123e-04 -0.0008663472 -8.464764e-04 -0.0008227666
## ASV0236      4.172918e-03  0.0044950753  4.836340e-03  0.0051974390
## ASV0250      1.439827e-02  0.0151142732  1.586396e-02  0.0166486680
## ASV0338      5.198983e-03  0.0053899033  5.584988e-03  0.0057841076
## ASV0450     -1.931076e-03 -0.0020442750 -2.163549e-03 -0.0022891529
## ASV0377      7.865975e-03  0.0081121638  8.362137e-03  0.0086156910
## ASV1022      7.299668e-05  0.0001035644  1.376691e-04  0.0001756023
## ASV6174     -8.279735e-04 -0.0008813716 -9.370346e-04 -0.0009948874
## ASV0786     -2.827519e-03 -0.0029776928 -3.133764e-03 -0.0032957581
## ASV0053     -9.623217e-03 -0.0099769819 -1.034073e-02 -0.0107145622
## ASV0697     -4.968319e-03 -0.0051285515 -5.292872e-03 -0.0054614103
## ASV0785      1.106967e-02  0.0114348292  1.180834e-02  0.0121902649
## ASV1967     -1.091749e-02 -0.0112844048 -1.166037e-02 -0.0120454591
## ASV0385      4.812289e-03  0.0050018520  5.196314e-03  0.0053955654
## ASV0295      2.241077e-03  0.0023846837  2.536473e-03  0.0026968018
## ASV0072     -7.796060e-03 -0.0080103236 -8.225739e-03 -0.0084420037
## ASV0157      1.176642e-03  0.0013208682  1.476305e-03  0.0016435741
## ASV0501      2.097238e-02  0.0217361788  2.251958e-02  0.0233225344
## ASV10729    -2.772926e-02 -0.0288192436 -2.994507e-02 -0.0311074800
## ASV1470      8.923508e-03  0.0090887330  9.248455e-03  0.0094019908
## ASV0050     -2.037806e-02 -0.0210446152 -2.172484e-02 -0.0224185966
## ASV0411     -5.934087e-03 -0.0061915216 -6.459457e-03 -0.0067382997
## ASV0549      8.925319e-03  0.0092816298  9.649664e-03  0.0100296323
## ASV0184      2.723034e-03  0.0028324676  2.946400e-03  0.0030650497
## ASV0705      4.344565e-03  0.0044584733  4.572242e-03  0.0046856170
## ASV1715      1.138914e-02  0.0118063322  1.223523e-02  0.0126759514
## ASV0603      2.357983e-03  0.0024810178  2.611035e-03  0.0027484370
## ASV0826      1.825180e-02  0.0188948678  1.955544e-02  0.0202338040
## ASV0034     -5.201912e-03 -0.0053559941 -5.512169e-03 -0.0056703420
## ASV0838     -1.673158e-03 -0.0020055926 -2.368441e-03 -0.0027637166
## ASV0614     -4.964656e-03 -0.0051378795 -5.315646e-03 -0.0054980134
## ASV0014     -1.335149e-02 -0.0138181964 -1.429664e-02 -0.0147868685
## ASV0585     -2.102849e-03 -0.0023056655 -2.520481e-03 -0.0027475872
## ASV0016     -1.396658e-02 -0.0144556575 -1.495712e-02 -0.0154710265
## ASV5394     -1.115228e-02 -0.0115648326 -1.198854e-02 -0.0124233806
## ASV0666      1.957175e-02  0.0201422575  2.072101e-02  0.0213078042
## ASV2085     -6.407537e-04 -0.0008869096 -1.153369e-03 -0.0014411270
## ASV0003     -9.502230e-03 -0.0098346902 -1.017561e-02 -0.0105250525
## ASV0346      5.790952e-03  0.0060223992  6.260622e-03  0.0065056218
## ASV0267      1.064384e-03  0.0011328777  1.203625e-03  0.0012764728
## ASV0353      9.047137e-03  0.0094221940  9.810585e-03  0.0102126191
## ASV2419      1.964790e-02  0.0203027136  2.097156e-02  0.0216542593
## ASV0447      1.329605e-02  0.0138444324  1.441212e-02  0.0149995928
## ASV0654      1.655460e-02  0.0171290148  1.771719e-02  0.0183191047
## ASV0151      3.808186e-03  0.0040068275  4.214648e-03  0.0044319229
## ASV0065     -6.122661e-03 -0.0063268958 -6.535747e-03 -0.0067492207
## ASV0527      1.558639e-02  0.0161276487  1.668230e-02  0.0172503826
## ASV4055     -4.060319e-03 -0.0042899300 -4.533414e-03 -0.0047916285
## ASV0166     -6.764869e-03 -0.0069606435 -7.159169e-03 -0.0073603867
## ASV0417     -2.037008e-03 -0.0020634928 -2.088005e-03 -0.0021104067
## ASV0078     -4.004544e-03 -0.0041117150 -4.218917e-03 -0.0043259255
## ASV0322      9.649815e-04  0.0010939729  1.233867e-03  0.0013852949
## ASV0156     -1.259664e-02 -0.0131077008 -1.363729e-02 -0.0141859831
## ASV0648     -2.761466e-02 -0.0287234076 -2.986953e-02 -0.0310537618
## ASV0407     -2.433566e-03 -0.0025486011 -2.668925e-03 -0.0027947563
## ASV2030     -4.574036e-03 -0.0047903911 -5.018139e-03 -0.0052578774
## ASV0300      3.600721e-03  0.0037523994  3.909293e-03  0.0040714803
## ASV1150      1.081374e-03  0.0011318449  1.183939e-03  0.0012376290
## ASV0958      1.174685e-02  0.0122855001  1.284726e-02  0.0134329762
## ASV0216     -9.851682e-03 -0.0102268915 -1.061615e-02 -0.0110200542
## ASV0446      1.677565e-02  0.0174306664  1.810605e-02  0.0188020767
## ASV0367     -1.053006e-02 -0.0109316500 -1.134567e-02 -0.0117723325
## ASV0200     -6.113340e-03 -0.0063355958 -6.563533e-03 -0.0067971205
## ASV0334     -1.533844e-03 -0.0015448134 -1.555078e-03 -0.0015647499
## ASV1311      2.092098e-03  0.0020946520  2.092515e-03  0.0020853464
## ASV0458      3.025673e-03  0.0030389336  3.047188e-03  0.0030501265
## ASV1371      1.219967e-03  0.0012665547  1.313865e-03  0.0013618025
## ASV0418      1.092766e-02  0.0112429084  1.156268e-02  0.0118868567
## ASV0004      1.510387e-03  0.0015506654  1.591292e-03  0.0016322386
## ASV1943      1.979795e-02  0.0200261619  2.023918e-02  0.0204362281
## ASV1495     -6.408378e-03 -0.0067940879 -7.200732e-03 -0.0076291728
## ASV0901     -1.322634e-02 -0.0137979416 -1.439271e-02 -0.0150114675
## ASV0628      3.907117e-03  0.0039646897  4.018309e-03  0.0040675788
## ASV0400      2.879928e-03  0.0029452490  3.009043e-03  0.0030709962
## ASV0116     -3.810935e-03 -0.0039709185 -4.136940e-03 -0.0043091812
## ASV0788      3.422443e-02  0.0356874048  3.720801e-02  0.0387882348
## ASV0117      2.817855e-03  0.0029447543  3.076667e-03  0.0032137291
## ASV3137     -5.608385e-04 -0.0005742919 -5.874196e-04 -0.0006001362
## ASV0001      1.562722e-03  0.0016015824  1.640614e-03  0.0016797934
## ASV1651      4.774620e-03  0.0049104268  5.048314e-03  0.0051882885
## ASV1692      2.795969e-02  0.0291238873  3.033128e-02  0.0315831629
## ASV0660      5.000590e-03  0.0050275487  5.044946e-03  0.0050520545
## ASV0508      2.235277e-04  0.0002228462  2.214148e-04  0.0002191497
## ASV1660     -6.819793e-03 -0.0071271654 -7.445699e-03 -0.0077755404
## ASV0233      7.821681e-03  0.0081176527  8.422785e-03  0.0087372578
## ASV1343     -1.578749e-02 -0.0164451991 -1.712770e-02 -0.0178357634
## ASV0209      5.250035e-03  0.0053774863  5.504616e-03  0.0056311932
## ASV0193     -6.311003e-03 -0.0064662373 -6.620803e-03 -0.0067743723
## ASV0357      5.473896e-03  0.0057808769  6.104590e-03  0.0064458305
## ASV0198      5.741482e-03  0.0059420184  6.148389e-03  0.0063607505
## ASV0007      1.245624e-03  0.0012703365  1.294681e-03  0.0013186226
## ASV1772     -6.496085e-04 -0.0005516321 -4.392225e-04 -0.0003110521
## ASV0009      9.135331e-04  0.0009260033  9.377892e-04  0.0009488580
## ASV0006     -2.108264e-03 -0.0022018035 -2.298938e-03 -0.0023997541
## ASV0011     -6.293720e-03 -0.0065446557 -6.804111e-03 -0.0070722859
## ASV0015      6.581435e-04  0.0006640735  6.691073e-04  0.0006731795
## ASV0017      7.793520e-04  0.0007898147  7.995938e-04  0.0008086375
## ASV0235     -5.950008e-03 -0.0061928161 -6.444409e-03 -0.0067050531
## ASV0382      4.164973e-03  0.0042930726  4.421230e-03  0.0045490317
## ASV2357      1.904399e-02  0.0198148319  2.061305e-02  0.0214393779
## ASV0567     -4.112348e-03 -0.0043053589 -4.507687e-03 -0.0047197847
## ASV0165      3.074239e-03  0.0031908198  3.310794e-03  0.0034341958
## ASV0005      4.008703e-03  0.0041446229  4.283532e-03  0.0044254018
## ASV0384      7.578335e-04  0.0008385633  9.254672e-04  0.0010189069
## ASV0002      6.755511e-04  0.0006975754  7.201597e-04  0.0007433136
## ASV3017      1.769591e-02  0.0181710489  1.864963e-02  0.0191312311
## ASV0091     -6.119968e-04 -0.0006421582 -6.742100e-04 -0.0007082959
## ASV0186     -8.258793e-03 -0.0085415559 -8.830285e-03 -0.0091248601
## ASV0370      4.062200e-03  0.0041958783  4.332841e-03  0.0044731635
## ASV0018      5.242630e-03  0.0054254605  5.612729e-03  0.0058044344
## ASV1377      4.538193e-02  0.0467176734  4.807261e-02  0.0494461450
## ASV0019      5.544760e-03  0.0057403292  5.940835e-03  0.0061462955
## ASV0023     -3.937734e-03 -0.0040941315 -4.255442e-03 -0.0044217214
## ASV2194      6.994734e-03  0.0073094655  7.637463e-03  0.0079791942
## ASV1155      1.978811e-02  0.0204512398  2.113243e-02  0.0218321455
## ASV0510     -3.945171e-03 -0.0040290911 -4.113725e-03 -0.0041991825
## ASV2371     -1.166554e-02 -0.0120304249 -1.240225e-02 -0.0127809144
## ASV0024     -4.853427e-03 -0.0050451203 -5.242846e-03 -0.0054466789
## ASV2452      9.168373e-03  0.0093338167  9.494170e-03  0.0096489372
## ASV2332     -3.557056e-02 -0.0367903608 -3.804306e-02 -0.0393292154
## ASV2591      1.421310e-02  0.0148190193  1.544338e-02  0.0160861702
## ASV0521      9.973987e-03  0.0103803545  1.080108e-02  0.0112365416
## ASV5542      9.240854e-03  0.0095968137  9.963984e-03  0.0103426000
## ASV0336     -2.314135e-03 -0.0024436995 -2.579787e-03 -0.0027226780
## ASV10102     1.712536e-02  0.0177854737  1.846529e-02  0.0191650265
## ASV16823    -1.875856e-02 -0.0192794411 -1.980782e-02 -0.0203436008
## ASV3104      9.705911e-02  0.0997539923  1.024876e-01  0.1052595121
## ASV0781      1.738757e-02  0.0180255427  1.868327e-02  0.0193612585
## ASV10899     1.624189e-02  0.0170586160  1.791270e-02  0.0188054809
## ASV11222    -3.301634e-02 -0.0339329552 -3.486275e-02 -0.0358055244
## ASV11327    -2.964231e-02 -0.0304651908 -3.129989e-02 -0.0321462370
## ASV12458    -3.301517e-02 -0.0339316146 -3.486121e-02 -0.0358037706
## ASV1636      2.124796e-02  0.0219218737  2.261001e-02  0.0233124106
## ASV1890     -1.269351e-02 -0.0129698894 -1.324767e-02 -0.0135269404
## ASV2898      2.865620e-02  0.0295714147  3.050631e-02  0.0314610159
## ASV8328      1.314946e-02  0.0139729277  1.484057e-02  0.0157540829
## ASV0709     -3.372071e-02 -0.0348440128 -3.599245e-02 -0.0371660136
## ASV0856      3.541232e-02  0.0368874219  3.841397e-02  0.0399929922
## ASV0909      1.617924e-02  0.0170448245  1.795083e-02  0.0188985499
## ASV0937     -2.431954e-02 -0.0253662973 -2.645580e-02 -0.0275895934
## ASV11390    -4.711802e-02 -0.0484256623 -4.975204e-02 -0.0510968745
## ASV11966     1.854275e-02  0.0193370013  2.015898e-02  0.0210091480
## ASV12990     8.873176e-03  0.0091354104  9.402498e-03  0.0096744916
## ASV14797     1.274164e-02  0.0131090893  1.348283e-02  0.0138628928
## ASV14904    -6.761177e-02 -0.0694879776 -7.139104e-02 -0.0733205584
## ASV15304     1.312390e-02  0.0137219523  1.434225e-02  0.0149851786
## ASV16696    -2.336077e-02 -0.0240089805 -2.466647e-02 -0.0253330937
## ASV1690      5.855080e-02  0.0608494274  6.321449e-02  0.0656461950
## ASV2029      3.335230e-02  0.0345024350  3.568262e-02  0.0368932426
## ASV2834      4.684005e-02  0.0486014684  5.041318e-02  0.0522755973
## ASV4003      4.954159e-02  0.0519248559  5.441945e-02  0.0570301827
## ASV4064      2.291337e-02  0.0238043847  2.472372e-02  0.0256719527
## ASV4294      1.912537e-02  0.0200713163  2.106024e-02  0.0220937061
## ASV4609      1.133181e-02  0.0117383240  1.215792e-02  0.0125910154
## ASV6283     -2.183682e-02 -0.0224426943 -2.305723e-02 -0.0236802994
## ASV6491     -3.129860e-02 -0.0321669666 -3.304774e-02 -0.0339407529
## ASV7453      2.522444e-02  0.0263261646  2.746770e-02  0.0286497958
## ASV7959      1.259208e-02  0.0132568886  1.395335e-02  0.0146826669
## ASV8219      2.704843e-01  0.2779884692  2.855999e-01  0.2933169800
## ASV8547     -2.802126e-02 -0.0287986534 -2.958716e-02 -0.0303866085
## ASV9319      1.865707e-02  0.0194597638  2.029420e-02  0.0211614589
## ASV9382     -5.482706e-02 -0.0563480964 -5.789088e-02 -0.0594550868
## ASV11516    -3.661990e-02 -0.0376358191 -3.866626e-02 -0.0397110258
## ASV14377    -2.644145e-02 -0.0271749906 -2.791903e-02 -0.0286734028
## ASV1867      2.909871e-02  0.0302645712  3.147081e-02  0.0327185187
## ASV1895      8.519452e-03  0.0086329455  8.737263e-03  0.0088316480
## ASV3168      1.287998e-02  0.0132032513  1.352759e-02  0.0138527023
## ASV4449      9.261256e-02  0.0961103568  9.972210e-02  0.1034507673
## ASV6596      2.692108e-02  0.0282207426  2.957856e-02  0.0309965964
## ASV7492      2.891675e-03  0.0032130908  3.555155e-03  0.0039186289
## ASV9854     -5.403702e-03 -0.0055471099 -5.692123e-03 -0.0058386714
## ASV6296      4.437035e-01  0.4560130355  4.684987e-01  0.4811579511
## ASV4201      1.013989e-02  0.0107952566  1.148779e-02  0.0122191520
## ASV0552      1.954340e-02  0.0202906665  2.106002e-02  0.0218516412
## ASV3671     -1.256300e-02 -0.0130906511 -1.364176e-02 -0.0142174828
## ASV3529      1.217103e-03  0.0013787304  1.548710e-03  0.0017270809
## ASV1060      6.291969e-03  0.0065919399  6.906148e-03  0.0072352388
## ASV0239     -4.567954e-03 -0.0046669774 -4.765314e-03 -0.0048628027
## ASV5711     -2.742840e-02 -0.0283680237 -2.933209e-02 -0.0303208640
## ASV4152     -4.329659e-02 -0.0449141154 -4.657844e-02 -0.0482899874
## ASV1461      1.521987e-02  0.0155674095  1.591426e-02  0.0162600607
## ASV2877      8.201377e-03  0.0083914377  8.580245e-03  0.0087674143
## ASV0012      1.929540e-03  0.0020018873  2.076479e-03  0.0021533583
## ASV9823     -1.391204e-04 -0.0002697688 -4.129151e-04 -0.0005692784
## ASV0008      2.012301e-03  0.0020865879  2.163151e-03  0.0022420374
## ASV7832     -2.677500e-02 -0.0278415769 -2.894428e-02 -0.0300838755
## ASV1915     -3.154808e-03 -0.0032907512 -3.433050e-03 -0.0035819995
## ASV0055     -3.306059e-03 -0.0034705879 -3.642625e-03 -0.0038224434
## ASV0032      4.232071e-04  0.0004204122  4.169034e-04  0.0004127004
## ASV2977     -3.520572e-02 -0.0364882184 -3.780536e-02 -0.0391572775
## ASV0466      2.016097e-02  0.0206082370  2.105204e-02  0.0214916230
## ASV3866      2.209671e-02  0.0230315188  2.400265e-02  0.0250113152
## ASV0040      7.317499e-03  0.0075988036  7.888949e-03  0.0081880902
## ASV0496     -5.071089e-03 -0.0053794576 -5.703267e-03 -0.0060429695
## ASV0052      6.187111e-03  0.0064278488  6.676577e-03  0.0069335020
## ASV3828     -1.551998e-02 -0.0159405692 -1.636642e-02 -0.0167973851
## ASV1930      8.391176e-03  0.0086126450  8.835214e-03  0.0090586672
## ASV2126      1.677072e-02  0.0173580947  1.796192e-02  0.0185825291
## ASV0793      2.413773e-02  0.0251076095  2.611077e-02  0.0271480276
## ASV0299     -1.130938e-03 -0.0012233565 -1.323523e-03 -0.0014320056
## ASV0208      1.674249e-02  0.0174054232  1.809167e-02  0.0188019190
## ASV0511     -4.349733e-03 -0.0044436829 -4.538090e-03 -0.0046330271
## ASV1123     -1.420127e-02 -0.0145371757 -1.487256e-02 -0.0152068525
## ASV0099      1.202450e-03  0.0012763113  1.354535e-03  0.0014373326
## ASV0752     -1.366984e-02 -0.0142658573 -1.488529e-02 -0.0155288706
## ASV0883      1.815531e-02  0.0189082435  1.968658e-02  0.0204907052
## ASV0683      2.308967e-02  0.0240474977  2.503971e-02  0.0260671472
## ASV4117     -3.437772e-02 -0.0357564724 -3.718418e-02 -0.0386622053
## ASV2172      4.386052e-04  0.0003856958  3.265035e-04  0.0002606195
## ASV0330     -6.611320e-03 -0.0068825993 -7.164021e-03 -0.0074559225
## ASV0728      2.899380e-02  0.0300271451  3.108882e-02  0.0321792448
## ASV0499      9.225784e-03  0.0096189224  1.002687e-02  0.0104500337
## ASV0120     -1.287256e-02 -0.0133216977 -1.378142e-02 -0.0142516543
## ASV1446      4.146487e-03  0.0040730340  3.983128e-03  0.0038756576
## ASV17171    -2.606668e-02 -0.0270861982 -2.814161e-02 -0.0292339942
## ASV0533      2.600314e-03  0.0027215750  2.847769e-03  0.0029790226
## ASV2495     -1.018746e-02 -0.0107186915 -1.127444e-02 -0.0118554432
## ASV5582      6.512914e-03  0.0065661281  6.610286e-03  0.0066446853
## ASV1488      3.393481e-03  0.0034629440  3.530022e-03  0.0035943550
## ASV0682      6.809496e-03  0.0070984704  7.397875e-03  0.0077079313
## ASV0068     -9.940972e-03 -0.0102914405 -1.064997e-02 -0.0110164354
## ASV1987     -3.043953e-02 -0.0317638166 -3.313842e-02 -0.0345646767
## ASV0035     -4.583381e-03 -0.0048786445 -5.192043e-03 -0.0055245373
## ASV7192     -1.387772e-02 -0.0143253644 -1.478156e-02 -0.0152461019
## ASV0873     -3.454511e-02 -0.0368021039 -3.916722e-02 -0.0416429203
## ASV4749     -7.512203e-03 -0.0080522028 -8.623311e-03 -0.0092267271
## ASV2174      6.271544e-03  0.0063341748  6.388833e-03  0.0064349416
## ASV1476     -1.348934e-02 -0.0140913452 -1.471773e-02 -0.0153692332
## ASV0740     -3.704504e-02 -0.0386503295 -4.031928e-02 -0.0420540149
## ASV0170     -6.335799e-03 -0.0065794592 -6.831131e-03 -0.0070910187
## ASV2466     -2.945093e-02 -0.0306143040 -3.181774e-02 -0.0330622680
## ASV1709      1.009152e-02  0.0105254976  1.098155e-02  0.0114610959
## ASV6170     -4.908970e-02 -0.0511097934 -5.320211e-02 -0.0553684390
## ASV3673      2.519976e-02  0.0262706351  2.738122e-02  0.0285325114
## ASV1745     -7.601923e-03 -0.0079597151 -8.332543e-03 -0.0087208539
##                                                                    
## (Intercept)  0.1706553926  1.765528e-01  1.825919e-01  1.887728e-01
## ASV1236      0.0284491953  2.930428e-02  3.017546e-02  3.106266e-02
## ASV0421      0.0074615663  7.825794e-03  8.203195e-03  8.593857e-03
## ASV0691     -0.0146330149 -1.484620e-02 -1.505411e-02 -1.525657e-02
## ASV0899      0.0239851264  2.464636e-02  2.531554e-02  2.599246e-02
## ASV1004      0.0567777907  5.844264e-02  6.013529e-02  6.185549e-02
## ASV1041     -0.0210194121 -2.148986e-02 -2.195560e-02 -2.241569e-02
## ASV1058      0.0356185776  3.668738e-02  3.777660e-02  3.888626e-02
## ASV12542     0.0124504289  1.279397e-02  1.314414e-02  1.350114e-02
## ASV1294      0.0335116457  3.453870e-02  3.558755e-02  3.665844e-02
## ASV13113     0.0176063372  1.841091e-02  1.924932e-02  2.012272e-02
## ASV1318      0.0328923423  3.386666e-02  3.485875e-02  3.586867e-02
## ASV2269     -0.0546898642 -5.616760e-02 -5.765911e-02 -5.916335e-02
## ASV2542      0.0374882938  3.900183e-02  4.056874e-02  4.219043e-02
## ASV2660     -0.0214641592 -2.204931e-02 -2.264168e-02 -2.324108e-02
## ASV2737      0.0062878760  6.442315e-03  6.599509e-03  6.759590e-03
## ASV2840      0.0242977339  2.478828e-02  2.527441e-02  2.575554e-02
## ASV3053      0.1418102507  1.456821e-01  1.496151e-01  1.536093e-01
## ASV3077      0.0094399595  9.719935e-03  1.000615e-02  1.029876e-02
## ASV3134      0.0262723387  2.742432e-02  2.862256e-02  2.986856e-02
## ASV3140      0.0284421910  2.943632e-02  3.045524e-02  3.149904e-02
## ASV3579      0.0146960211  1.537406e-02  1.607838e-02  1.680950e-02
## ASV6119     -0.0149587469 -1.536250e-02 -1.577008e-02 -1.618124e-02
## ASV7557     -0.0303970010 -3.121745e-02 -3.204573e-02 -3.288136e-02
## ASV8422      0.0074254973  7.645222e-03  7.870192e-03  8.100570e-03
## ASV1086     -0.0008643708 -8.897705e-04 -9.165377e-04 -9.447714e-04
## ASV1310      0.0148650394  1.528495e-02  1.571045e-02  1.614136e-02
## ASV15750    -0.0012307669 -1.230771e-03 -1.228309e-03 -1.223248e-03
## ASV16905    -0.0062499272 -6.418738e-03 -6.589209e-03 -6.761250e-03
## ASV2033      0.0380699264  3.956710e-02  4.111165e-02  4.270442e-02
## ASV2089      0.0132137427  1.357055e-02  1.393078e-02  1.429424e-02
## ASV2127      0.0444189579  4.573067e-02  4.706604e-02  4.842506e-02
## ASV2725      0.0325826851  3.343556e-02  3.429739e-02  3.516785e-02
## ASV2804     -0.0129383889 -1.328810e-02 -1.364131e-02 -1.399785e-02
## ASV3075      0.0362873607  3.769217e-02  3.914706e-02  4.065360e-02
## ASV3327      0.0529472207  5.495864e-02  5.703127e-02  5.916615e-02
## ASV3342      0.0447802483  4.648629e-02  4.824662e-02  5.006242e-02
## ASV3532     -0.0476500680 -4.945639e-02 -5.132427e-02 -5.325576e-02
## ASV3600      0.0222561898  2.307917e-02  2.392650e-02  2.479854e-02
## ASV4013      0.0363656955  3.752151e-02  3.870035e-02  3.990199e-02
## ASV4136      0.0342467148  3.523231e-02  3.623552e-02  3.725641e-02
## ASV4195      0.1320920675  1.356660e-01  1.392766e-01  1.429221e-01
## ASV4407     -0.0510398290 -5.242120e-02 -5.381680e-02 -5.522598e-02
## ASV4717      0.0068787394  7.034384e-03  7.192784e-03  7.354134e-03
## ASV6794      0.0198021273  2.035738e-02  2.092394e-02  2.150205e-02
## ASV8324     -0.0261919924 -2.690142e-02 -2.761825e-02 -2.834216e-02
## ASV8981      0.0015767733  1.717581e-03  1.866955e-03  2.025190e-03
## ASV9859      0.0187294928  1.970650e-02  2.073210e-02  2.180839e-02
## ASV0936      0.0327447958  3.390769e-02  3.509954e-02  3.632040e-02
## ASV12683    -0.0003723334 -3.798983e-04 -3.862644e-04 -3.912798e-04
## ASV1293      0.0170470797  1.752353e-02  1.800661e-02  1.849623e-02
## ASV13055     0.0011421513  1.240547e-03  1.344808e-03  1.455140e-03
## ASV17063    -0.0135955276 -1.396420e-02 -1.433677e-02 -1.471306e-02
## ASV2228      0.0110884113  1.138916e-02  1.169310e-02  1.200008e-02
## ASV2769      0.0036727261  3.837167e-03  4.006419e-03  4.180400e-03
## ASV2803      0.0102369823  1.047746e-02  1.072005e-02  1.096478e-02
## ASV2896      0.0141688908  1.478814e-02  1.543374e-02  1.610673e-02
## ASV3062      0.0193700147  2.021736e-02  2.109512e-02  2.200382e-02
## ASV3107      0.0242614779  2.521402e-02  2.619864e-02  2.721609e-02
## ASV3265      0.0239812922  2.463608e-02  2.529909e-02  2.597010e-02
## ASV3666     -0.0002128208 -2.389053e-04 -2.667592e-04 -2.964462e-04
## ASV4497      0.0088991729  9.170261e-03  9.446594e-03  9.728171e-03
## ASV6914     -0.0026805039 -2.807621e-03 -2.939560e-03 -3.076413e-03
## ASV0576     -0.0235383378 -2.402752e-02 -2.451559e-02 -2.500219e-02
## ASV0673      0.0356561439  3.678522e-02  3.793891e-02  3.911743e-02
## ASV0772      0.0177678578  1.839175e-02  1.903375e-02  1.969425e-02
## ASV0862      0.0067174351  7.080321e-03  7.456501e-03  7.845980e-03
## ASV0898      0.0167740736  1.742776e-02  1.810109e-02  1.879432e-02
## ASV0910      0.0184844479  1.921146e-02  1.996264e-02  2.073853e-02
## ASV0964     -0.0094193855 -9.631376e-03 -9.843936e-03 -1.005698e-02
## ASV10059     0.0151863794  1.584215e-02  1.652215e-02  1.722692e-02
## ASV10263    -0.0207042319 -2.126697e-02 -2.183578e-02 -2.241035e-02
## ASV1088      0.0326044256  3.391865e-02  3.528116e-02  3.669346e-02
## ASV1101      0.0293100346  3.010960e-02  3.091898e-02  3.173791e-02
## ASV1183      0.0098442004  1.020536e-02  1.057777e-02  1.096172e-02
## ASV11956     0.0062045667  6.350820e-03  6.499260e-03  6.650011e-03
## ASV12774    -0.0012668483 -1.366266e-03 -1.470884e-03 -1.580833e-03
## ASV1321      0.0491592271  5.110648e-02  5.311595e-02  5.518856e-02
## ASV13793    -0.0142779768 -1.466617e-02 -1.505854e-02 -1.545488e-02
## ASV14482     0.0007837432  8.159496e-04  8.500810e-04  8.862539e-04
## ASV15483     0.0077717466  8.059670e-03  8.355839e-03  8.660375e-03
## ASV2062      0.0312888342  3.233083e-02  3.339893e-02  3.449346e-02
## ASV2132      0.0293785427  3.046567e-02  3.158365e-02  3.273279e-02
## ASV2413      0.0226204500  2.332874e-02  2.405324e-02  2.479422e-02
## ASV2490      0.0603390371  6.188448e-02  6.344571e-02  6.502227e-02
## ASV2594      0.0111536302  1.161745e-02  1.209988e-02  1.260160e-02
## ASV2822     -0.0376738441 -3.869839e-02 -3.973399e-02 -4.078009e-02
## ASV2863      0.0399297254  4.107252e-02  4.223494e-02  4.341696e-02
## ASV2910      0.0149255712  1.535980e-02  1.580185e-02  1.625176e-02
## ASV2980      0.0186045574  1.920823e-02  1.982550e-02  2.045644e-02
## ASV3307      0.0299839089  3.079945e-02  3.162381e-02  3.245657e-02
## ASV3474      0.0293661114  3.056555e-02  3.180543e-02  3.308649e-02
## ASV3502      0.0256931949  2.662079e-02  2.757635e-02  2.856056e-02
## ASV4236      0.0270088441  2.763677e-02  2.826718e-02  2.889979e-02
## ASV4842     -0.0033850205 -3.443792e-03 -3.498941e-03 -3.550100e-03
## ASV4894     -0.0142817214 -1.467029e-02 -1.506308e-02 -1.545991e-02
## ASV5290      0.0145335378  1.506157e-02  1.560483e-02  1.616363e-02
## ASV5501      0.0095334912  9.942681e-03  1.036974e-02  1.081545e-02
## ASV5795      0.0100289660  1.039926e-02  1.077991e-02  1.117100e-02
## ASV5987     -0.0398902307 -4.097593e-02 -4.207354e-02 -4.318252e-02
## ASV6267     -0.0449522596 -4.617592e-02 -4.741304e-02 -4.866304e-02
## ASV6862      0.0172112886  1.768563e-02  1.816780e-02  1.865786e-02
## ASV7145      0.0078507284  8.104861e-03  8.366916e-03  8.637163e-03
## ASV7673     -0.0142841587 -1.467315e-02 -1.506645e-02 -1.546388e-02
## ASV7789      0.0136014991  1.426372e-02  1.495488e-02  1.567591e-02
## ASV7809      0.0025791138  2.728272e-03  2.883782e-03  3.045736e-03
## ASV8002     -0.0180426691 -1.853433e-02 -1.903151e-02 -1.953401e-02
## ASV8205      0.0098205746  1.019060e-02  1.057203e-02  1.096503e-02
## ASV9155     -0.0039194267 -3.997686e-03 -4.074852e-03 -4.150792e-03
## ASV9221      0.0060847561  6.436777e-03  6.806376e-03  7.194188e-03
## ASV9311     -0.0289509114 -2.974077e-02 -3.053970e-02 -3.134739e-02
## ASV9557     -0.0197883445 -2.032845e-02 -2.087480e-02 -2.142719e-02
## ASV9936     -0.0399112853 -4.100110e-02 -4.210362e-02 -4.321842e-02
## ASV1445      0.0309755632  3.210303e-02  3.326216e-02  3.445333e-02
## ASV4232      0.0157220581  1.648376e-02  1.728193e-02  1.811816e-02
## ASV6479      0.0093333901  9.861991e-03  1.041719e-02  1.099998e-02
## ASV0142     -0.0170952171 -1.757831e-02 -1.806915e-02 -1.856770e-02
## ASV0378      0.0120642962  1.255562e-02  1.306194e-02  1.358329e-02
## ASV1122      0.0312270536  3.241574e-02  3.364175e-02  3.490580e-02
## ASV0123     -0.0149200064 -1.533320e-02 -1.575235e-02 -1.617738e-02
## ASV2064      0.0051738544  5.199200e-03  5.215928e-03  5.223458e-03
## ASV4459     -0.0005627179 -5.789173e-04 -5.972802e-04 -6.180934e-04
## ASV0448      0.0097962095  1.020929e-02  1.063678e-02  1.107894e-02
## ASV0397      0.0161563225  1.669521e-02  1.724679e-02  1.781114e-02
## ASV0485      0.0178449479  1.841962e-02  1.900738e-02  1.960835e-02
## ASV1566      0.0273945074  2.830282e-02  2.923236e-02  3.018325e-02
## ASV1365      0.0242545558  2.505874e-02  2.587946e-02  2.671654e-02
## ASV1065      0.0350671702  3.629198e-02  3.754860e-02  3.883731e-02
## ASV0722     -0.0025569422 -2.685902e-03 -2.821492e-03 -2.964021e-03
## ASV12660    -0.0158551517 -1.628217e-02 -1.671454e-02 -1.715216e-02
## ASV0223      0.0051691645  5.349985e-03  5.536250e-03  5.728116e-03
## ASV0229      0.0092309317  9.596715e-03  9.975416e-03  1.036743e-02
## ASV0877      0.0005468319  4.194195e-04  2.768016e-04  1.179200e-04
## ASV0983      0.0168267747  1.732479e-02  1.783085e-02  1.834481e-02
## ASV0626      0.0051809366  5.446980e-03  5.723304e-03  6.010071e-03
## ASV4146     -0.0004618255 -5.779562e-04 -7.067674e-04 -8.491934e-04
## ASV4175     -0.0254168790 -2.634413e-02 -2.729690e-02 -2.827542e-02
## ASV2082     -0.0200890301 -2.115400e-02 -2.226951e-02 -2.343724e-02
## ASV2272      0.0123404912  1.281968e-02  1.331507e-02  1.382706e-02
## ASV2245     -0.0185771316 -1.926540e-02 -1.997297e-02 -2.070001e-02
## ASV0590     -0.0205929713 -2.169961e-02 -2.285886e-02 -2.407255e-02
## ASV0217      0.0057971511  6.152714e-03  6.525178e-03  6.915027e-03
## ASV0416      0.0067500906  6.778336e-03  6.796340e-03  6.803547e-03
## ASV1056      0.0191241801  1.986531e-02  2.062851e-02  2.141398e-02
## ASV7777     -0.0250112603 -2.598468e-02 -2.699344e-02 -2.803888e-02
## ASV0455      0.0040174030  4.144011e-03  4.272521e-03  4.402818e-03
## ASV0604      0.0133216540  1.386484e-02  1.442618e-02  1.500604e-02
## ASV6100     -0.0184787874 -1.924024e-02 -2.003116e-02 -2.085265e-02
## ASV11359    -0.0353450931 -3.657437e-02 -3.783281e-02 -3.912028e-02
## ASV6604      0.0057228757  5.947904e-03  6.179295e-03  6.417003e-03
## ASV5004     -0.0126460313 -1.311599e-02 -1.360132e-02 -1.410245e-02
## ASV1483     -0.0050755491 -5.242222e-03 -5.412408e-03 -5.586062e-03
## ASV9773     -0.0170391769 -1.770263e-02 -1.838887e-02 -1.909853e-02
## ASV4059      0.0039431387  4.202953e-03  4.474566e-03  4.758071e-03
## ASV1193      0.0183560149  1.898787e-02  1.963614e-02  2.030101e-02
## ASV4610      0.0012971734  1.440131e-03  1.588634e-03  1.742495e-03
## ASV0742      0.0021395726  2.319096e-03  2.506646e-03  2.702225e-03
## ASV1502     -0.0035390915 -3.738941e-03 -3.946897e-03 -4.163035e-03
## ASV0195     -0.0011012628 -1.186340e-03 -1.275811e-03 -1.369793e-03
## ASV1213      0.0089309165  9.107796e-03  9.282766e-03  9.455576e-03
## ASV1648     -0.0166729992 -1.737034e-02 -1.809568e-02 -1.885011e-02
## ASV6984     -0.0158317940 -1.650432e-02 -1.720448e-02 -1.793335e-02
## ASV0396      0.0004970054  5.220249e-04  5.450624e-04  5.656448e-04
## ASV4297      0.0142958620  1.464715e-02  1.500132e-02  1.535830e-02
## ASV2622      0.0255712946  2.634003e-02  2.712350e-02  2.792173e-02
## ASV3512      0.0186222941  1.956252e-02  2.054735e-02  2.157856e-02
## ASV2411      0.0244534383  2.544747e-02  2.647446e-02  2.753487e-02
## ASV2291     -0.0180025285 -1.894497e-02 -1.992868e-02 -2.095474e-02
## ASV0807      0.0264912696  2.735839e-02  2.824417e-02  2.914862e-02
## ASV1292      0.0038699748  3.930143e-03  3.989859e-03  4.049272e-03
## ASV1035      0.0214183002  2.207210e-02  2.274072e-02  2.342446e-02
## ASV0070      0.0022920125  2.446707e-03  2.609819e-03  2.781652e-03
## ASV0255      0.0008560521  8.115539e-04  7.599864e-04  7.008257e-04
## ASV0057     -0.0045094560 -4.583180e-03 -4.654240e-03 -4.722400e-03
## ASV0077     -0.0003421699 -3.245833e-04 -3.059148e-04 -2.862568e-04
## ASV0625      0.0111991423  1.148330e-02  1.176980e-02  1.205850e-02
## ASV2464      0.0771983982  7.926482e-02  8.135788e-02  8.347708e-02
## ASV1315      0.0325463918  3.389153e-02  3.528270e-02  3.672071e-02
## ASV2673      0.0282018898  2.938409e-02  3.060858e-02  3.187635e-02
## ASV2161      0.0120653716  1.258977e-02  1.313497e-02  1.370160e-02
## ASV0337     -0.0059552136 -6.182289e-03 -6.416675e-03 -6.658545e-03
## ASV7680     -0.0398906075 -4.143038e-02 -4.301900e-02 -4.465731e-02
## ASV0611      0.0227241773  2.363265e-02  2.457304e-02  2.554621e-02
## ASV3118     -0.0263313081 -2.743833e-02 -2.858453e-02 -2.977074e-02
## ASV1284     -0.0061758506 -6.908922e-03 -7.694924e-03 -8.536540e-03
## ASV0889      0.0139288676  1.440407e-02  1.489361e-02  1.539802e-02
## ASV4649     -0.0079089237 -8.202206e-03 -8.504634e-03 -8.816416e-03
## ASV1108     -0.0214057099 -2.236665e-02 -2.336526e-02 -2.440252e-02
## ASV0738      0.0150730707  1.585006e-02  1.666398e-02  1.751631e-02
## ASV0473     -0.0033129680 -3.449338e-03 -3.587369e-03 -3.726636e-03
## ASV0598     -0.0090156395 -9.514511e-03 -1.003848e-02 -1.058850e-02
## ASV0429      0.0085859751  8.787849e-03  8.989236e-03  9.189863e-03
## ASV1549      0.0262172500  2.731454e-02  2.844989e-02  2.962395e-02
## ASV1203      0.0148083493  1.526417e-02  1.572817e-02  1.620023e-02
## ASV4532      0.0002402245  2.534224e-04  2.689115e-04  2.869837e-04
## ASV0274      0.0038248417  3.968738e-03  4.115076e-03  4.263621e-03
## ASV0163     -0.0099786230 -1.026380e-02 -1.055522e-02 -1.085311e-02
## ASV1298      0.0012080254  1.286301e-03  1.372073e-03  1.465999e-03
## ASV9424     -0.0325908069 -3.394080e-02 -3.534186e-02 -3.679565e-02
## ASV0412      0.0250884522  2.585672e-02  2.663989e-02  2.743796e-02
## ASV0284      0.0021326831  2.065343e-03  1.987076e-03  1.897176e-03
## ASV0620     -0.0099785651 -1.046845e-02 -1.097921e-02 -1.151146e-02
## ASV0153     -0.0344799819 -3.589422e-02 -3.735539e-02 -3.886419e-02
## ASV0498      0.0102446356  1.058288e-02  1.092634e-02  1.127466e-02
## ASV0097      0.0068907745  7.179304e-03  7.477827e-03  7.786508e-03
## ASV0104     -0.0361270239 -3.727439e-02 -3.844380e-02 -3.963501e-02
## ASV1282      0.0092789458  9.425695e-03  9.563414e-03  9.691136e-03
## ASV3883     -0.0151036780 -1.575788e-02 -1.643390e-02 -1.713189e-02
## ASV0801      0.0060294893  6.282104e-03  6.545504e-03  6.820206e-03
## ASV1611     -0.0300610343 -3.130271e-02 -3.258845e-02 -3.391927e-02
## ASV0227     -0.0085131839 -8.947335e-03 -9.400640e-03 -9.873692e-03
## ASV0833      0.0089551023  9.280168e-03  9.614221e-03  9.957369e-03
## ASV0718      0.0401559281  4.163998e-02  4.316727e-02  4.473842e-02
## ASV1139     -0.0003144132 -5.107667e-04 -7.228738e-04 -9.513796e-04
## ASV0766     -0.0075701791 -7.899824e-03 -8.240723e-03 -8.592997e-03
## ASV2091      0.0232001659  2.375945e-02  2.432007e-02  2.488151e-02
## ASV1238     -0.0345777978 -3.610564e-02 -3.769987e-02 -3.936324e-02
## ASV9193     -0.0081554041 -8.657264e-03 -9.186639e-03 -9.744665e-03
## ASV0290      0.0018111600  1.837071e-03  1.864536e-03  1.893879e-03
## ASV0231      0.0095747448  9.840469e-03  1.010820e-02  1.037761e-02
## ASV0185      0.0113761495  1.195646e-02  1.256369e-02  1.319879e-02
## ASV2330      0.0090044848  9.211637e-03  9.420440e-03  9.630954e-03
## ASV3119     -0.0099046908 -1.039733e-02 -1.091203e-02 -1.144954e-02
## ASV2368     -0.0195327500 -2.044212e-02 -2.139219e-02 -2.238456e-02
## ASV0122     -0.0064405592 -6.649143e-03 -6.862469e-03 -7.080580e-03
## ASV1044      0.0217798570  2.269281e-02  2.363992e-02  2.462218e-02
## ASV0160     -0.0054809548 -5.623728e-03 -5.769346e-03 -5.917989e-03
## ASV0326      0.0019189837  1.973854e-03  2.028653e-03  2.083227e-03
## ASV1388      0.0335797824  3.464731e-02  3.573616e-02  3.684620e-02
## ASV0792      0.0219795762  2.258020e-02  2.318760e-02  2.380148e-02
## ASV0036     -0.0101770550 -1.058010e-02 -1.099496e-02 -1.142165e-02
## ASV2125      0.0248471230  2.565961e-02  2.648881e-02  2.733455e-02
## ASV1075     -0.0006696353 -7.140018e-04 -7.615924e-04 -8.126144e-04
## ASV0390      0.0180859743  1.889814e-02  1.974449e-02  2.062624e-02
## ASV3790     -0.0218665473 -2.271643e-02 -2.359417e-02 -2.450038e-02
## ASV1535     -0.0089984073 -9.422864e-03 -9.863926e-03 -1.032192e-02
## ASV0263      0.0247677642  2.565769e-02  2.657230e-02  2.751187e-02
## ASV0675      0.0419286302  4.360240e-02  4.533231e-02  4.711953e-02
## ASV3348      0.0040879377  4.264909e-03  4.447840e-03  4.636780e-03
## ASV0058     -0.0097401378 -1.004051e-02 -1.034614e-02 -1.065691e-02
## ASV4142      0.0119493017  1.227101e-02  1.259721e-02  1.292793e-02
## ASV0059     -0.0075289892 -7.749524e-03 -7.973247e-03 -8.200068e-03
## ASV0013     -0.0154836970 -1.602715e-02 -1.658495e-02 -1.715724e-02
## ASV0033     -0.0087889897 -9.138654e-03 -9.498958e-03 -9.869972e-03
## ASV4354     -0.0098552918 -1.024339e-02 -1.064480e-02 -1.105980e-02
## ASV0022     -0.0074642607 -7.765298e-03 -8.075920e-03 -8.396229e-03
## ASV0134     -0.0085426456 -8.951525e-03 -9.379206e-03 -9.826498e-03
## ASV0415      0.0016896508  1.762591e-03  1.837587e-03  1.914630e-03
## ASV10103    -0.0398824739 -4.147996e-02 -4.313091e-02 -4.483634e-02
## ASV1613      0.0203467437  2.085568e-02  2.136486e-02  2.187354e-02
## ASV0135     -0.0020689792 -2.100417e-03 -2.130462e-03 -2.159004e-03
## ASV0469     -0.0304492666 -3.146632e-02 -3.251028e-02 -3.358166e-02
## ASV0471      0.0202079773  2.093702e-02  2.168847e-02  2.246299e-02
## ASV0451     -0.0067610995 -7.109554e-03 -7.472577e-03 -7.850470e-03
## ASV0747      0.0119193738  1.233997e-02  1.277060e-02  1.321119e-02
## ASV1314     -0.0152420603 -1.593188e-02 -1.665064e-02 -1.739934e-02
## ASV0425     -0.0325757447 -3.346440e-02 -3.436508e-02 -3.527766e-02
## ASV0559     -0.0108791704 -1.133146e-02 -1.180284e-02 -1.229413e-02
## ASV0148      0.0004207354  5.400871e-04  6.693782e-04  8.091260e-04
## ASV0129      0.0075808543  8.046723e-03  8.537556e-03  9.054326e-03
## ASV1072      0.0008710205  8.301362e-04  7.838023e-04  7.317522e-04
## ASV2390      0.0135812623  1.378859e-02  1.398577e-02  1.417199e-02
## ASV0548      0.0133339531  1.377759e-02  1.423120e-02  1.469480e-02
## ASV0168     -0.0063391586 -6.539354e-03 -6.743954e-03 -6.953000e-03
## ASV0066     -0.0071205424 -7.328257e-03 -7.538152e-03 -7.750000e-03
## ASV0468     -0.0045782632 -4.758273e-03 -4.944862e-03 -5.138266e-03
## ASV0172     -0.0007949782 -7.628661e-04 -7.261791e-04 -6.846609e-04
## ASV0236      0.0055790985  5.982041e-03  6.406984e-03  6.854638e-03
## ASV0250      0.0174697819  1.832870e-02  1.922687e-02  2.016576e-02
## ASV0338      0.0059871162  6.193848e-03  6.404119e-03  6.617724e-03
## ASV0450     -0.0024213459 -2.560390e-03 -2.706551e-03 -2.860094e-03
## ASV0377      0.0088726010  9.132623e-03  9.395490e-03  9.660916e-03
## ASV1022      0.0002176717  2.642028e-04  3.155382e-04  3.720385e-04
## ASV6174     -0.0010548255 -1.116712e-03 -1.180372e-03 -1.245596e-03
## ASV0786     -0.0034636827 -3.637523e-03 -3.817240e-03 -4.002774e-03
## ASV0053     -0.0110985962 -1.149293e-02 -1.189765e-02 -1.231285e-02
## ASV0697     -0.0056343115 -5.811734e-03 -5.993853e-03 -6.180862e-03
## ASV0785      0.0125806898  1.297970e-02  1.338737e-02  1.380383e-02
## ASV1967     -0.0124397327 -1.284324e-02 -1.325603e-02 -1.367812e-02
## ASV0385      0.0055994755  5.807887e-03  6.020616e-03  6.237452e-03
## ASV0295      0.0028660376  3.044553e-03  3.232727e-03  3.430946e-03
## ASV0072     -0.0086588000 -8.875795e-03 -9.092643e-03 -9.308982e-03
## ASV0157      0.0018233152  2.016188e-03  2.222871e-03  2.444059e-03
## ASV0501      0.0241449415  2.498667e-02  2.584753e-02  2.672732e-02
## ASV10729    -0.0323071978 -3.354494e-02 -3.482141e-02 -3.613728e-02
## ASV1470      0.0095486289  9.687630e-03  9.818230e-03  9.939633e-03
## ASV0050     -0.0231257353 -2.384608e-02 -2.457944e-02 -2.532560e-02
## ASV0411     -0.0070284738 -7.330421e-03 -7.644600e-03 -7.971493e-03
## ASV0549      0.0104217355  1.082617e-02  1.124311e-02  1.167274e-02
## ASV0184      0.0031886464  3.317433e-03  3.451666e-03  3.591615e-03
## ASV0705      0.0047983301  4.910094e-03  5.020605e-03  5.129541e-03
## ASV1715      0.0131286252  1.359336e-02  1.407027e-02  1.455944e-02
## ASV0603      0.0028936466  3.047104e-03  3.209266e-03  3.380610e-03
## ASV0826      0.0209302335  2.164501e-02  2.237843e-02  2.313077e-02
## ASV0034     -0.0058304132 -5.992280e-03 -6.155835e-03 -6.320970e-03
## ASV0838     -0.0031935230 -3.660058e-03 -4.165613e-03 -4.712575e-03
## ASV0614     -0.0056850404 -5.876786e-03 -6.073310e-03 -6.274675e-03
## ASV0014     -0.0152889377 -1.580288e-02 -1.632871e-02 -1.686644e-02
## ASV0585     -0.0029872525 -3.239716e-03 -3.505186e-03 -3.783839e-03
## ASV0016     -0.0159974416 -1.653641e-02 -1.708796e-02 -1.765212e-02
## ASV5394     -0.0128693169 -1.332627e-02 -1.379412e-02 -1.427272e-02
## ASV0666      0.0219024260  2.250466e-02  2.311430e-02  2.373112e-02
## ASV2085     -0.0017511994 -2.084626e-03 -2.442466e-03 -2.825805e-03
## ASV0003     -0.0108830600 -1.124968e-02 -1.162495e-02 -1.200890e-02
## ASV0346      0.0067573823  7.015873e-03  7.281045e-03  7.552834e-03
## ASV0267      0.0013512366  1.427698e-03  1.505600e-03  1.584652e-03
## ASV0353      0.0106286024  1.105884e-02  1.150361e-02  1.196322e-02
## ASV2419      0.0223505895  2.306029e-02  2.378306e-02  2.451856e-02
## ASV0447      0.0156073227  1.623579e-02  1.688549e-02  1.755691e-02
## ASV0654      0.0189347491  1.956408e-02  2.020705e-02  2.086360e-02
## ASV0151      0.0046589229  4.895912e-03  5.143145e-03  5.400870e-03
## ASV0065     -0.0069673233 -7.190058e-03 -7.417429e-03 -7.649436e-03
## ASV0527      0.0178319038  1.842686e-02  1.903525e-02  1.965701e-02
## ASV4055     -0.0050654807 -5.355928e-03 -5.663980e-03 -5.990702e-03
## ASV0166     -0.0075642440 -7.770692e-03 -7.979690e-03 -8.191203e-03
## ASV0417     -0.0021305619 -2.148340e-03 -2.163614e-03 -2.176266e-03
## ASV0078     -0.0044325026 -4.538396e-03 -4.643340e-03 -4.747052e-03
## ASV0322      0.0015489061  1.725363e-03  1.915341e-03  2.119528e-03
## ASV0156     -0.0147543455 -1.534298e-02 -1.595249e-02 -1.658350e-02
## ASV0648     -0.0322768027 -3.353932e-02 -3.484195e-02 -3.618528e-02
## ASV0407     -0.0029263222 -3.063854e-03 -3.207590e-03 -3.357774e-03
## ASV2030     -0.0055102179 -5.775790e-03 -6.055237e-03 -6.349216e-03
## ASV0300      0.0042390339  4.412018e-03  4.590491e-03  4.774499e-03
## ASV1150      0.0012928771  1.349636e-03  1.407847e-03  1.467441e-03
## ASV0958      0.0140434784  1.467963e-02  1.534230e-02  1.603239e-02
## ASV0216     -0.0114392587 -1.187443e-02 -1.232627e-02 -1.279551e-02
## ASV0446      0.0195190005  2.025705e-02  2.101645e-02  2.179737e-02
## ASV0367     -0.0122118367 -1.266438e-02 -1.313014e-02 -1.360931e-02
## ASV0200     -0.0070363102 -7.281039e-03 -7.531225e-03 -7.786769e-03
## ASV0334     -0.0015739591 -1.582859e-03 -1.591625e-03 -1.600458e-03
## ASV1311      0.0020727990  2.054515e-03  2.030128e-03  1.999265e-03
## ASV0458      0.0030474351  3.038799e-03  3.023901e-03  3.002424e-03
## ASV1371      0.0014102628  1.459131e-03  1.508281e-03  1.557578e-03
## ASV0418      0.0122153182  1.254794e-02  1.288459e-02  1.322515e-02
## ASV0004      0.0016734781  1.714982e-03  1.756721e-03  1.798667e-03
## ASV1943      0.0206165689  2.077950e-02  2.092436e-02  2.105054e-02
## ASV1495     -0.0080802813 -8.554939e-03 -9.054035e-03 -9.578462e-03
## ASV0901     -0.0156550934 -1.632447e-02 -1.702052e-02 -1.774416e-02
## ASV0628      0.0041120873  4.151407e-03  4.185093e-03  4.212686e-03
## ASV0400      0.0031307752  3.188022e-03  3.242356e-03  3.293370e-03
## ASV0116     -0.0044878271 -4.673065e-03 -4.865083e-03 -5.064074e-03
## ASV0788      0.0404300974  4.213569e-02  4.390715e-02  4.574668e-02
## ASV0117      0.0033560775  3.503848e-03  3.657176e-03  3.816198e-03
## ASV3137     -0.0006123475 -6.239493e-04 -6.348270e-04 -6.448548e-04
## ASV0001      0.0017191006  1.758517e-03  1.798029e-03  1.837623e-03
## ASV1651      0.0053303659  5.474570e-03  5.620936e-03  5.769508e-03
## ASV1692      0.0328808574  3.422572e-02  3.561913e-02  3.706251e-02
## ASV0660      0.0050481318  5.032421e-03  5.004152e-03  4.962548e-03
## ASV0508      0.0002159598  2.117457e-04  2.063999e-04  1.998053e-04
## ASV1660     -0.0081168182 -8.469636e-03 -8.834074e-03 -9.210185e-03
## ASV0233      0.0090612486  9.394936e-03  9.738500e-03  1.009212e-02
## ASV1343     -0.0185701936 -1.933180e-02 -2.012141e-02 -2.093987e-02
## ASV0209      0.0057569760  5.881711e-03  6.005132e-03  6.126964e-03
## ASV0193     -0.0069266027 -7.077136e-03 -7.225599e-03 -7.371603e-03
## ASV0357      0.0068054157  7.184187e-03  7.583010e-03  8.002770e-03
## ASV0198      0.0065792657  6.804103e-03  7.035437e-03  7.273447e-03
## ASV0007      0.0013421287  1.365170e-03  1.387721e-03  1.409759e-03
## ASV1772     -0.0001656995 -1.645259e-06  1.827332e-04  3.891660e-04
## ASV0009      0.0009591810  9.687332e-04  9.774944e-04  9.854497e-04
## ASV0006     -0.0025043358 -2.612765e-03 -2.725122e-03 -2.841483e-03
## ASV0011     -0.0073493781 -7.635587e-03 -7.931109e-03 -8.236144e-03
## ASV0015      0.0006762232  6.781702e-04  6.789510e-04  6.784950e-04
## ASV0017      0.0008168936  8.243092e-04  8.308309e-04  8.364049e-04
## ASV0235     -0.0069750246 -7.254606e-03 -7.544088e-03 -7.843770e-03
## ASV0382      0.0046760257  4.801723e-03  4.925598e-03  5.047083e-03
## ASV2357      0.0222945170  2.317918e-02  2.409408e-02  2.503990e-02
## ASV0567     -0.0049421187 -5.175176e-03 -5.419459e-03 -5.675490e-03
## ASV0165      0.0035610578  3.691409e-03  3.825276e-03  3.962684e-03
## ASV0005      0.0045701999  4.717887e-03  4.868420e-03  5.021749e-03
## ASV0384      0.0011192586  1.226913e-03  1.342276e-03  1.465770e-03
## ASV0002      0.0007670464  7.913672e-04  8.162848e-04  8.418074e-04
## ASV3017      0.0196153972  2.010168e-02  2.058961e-02  2.107872e-02
## ASV0091     -0.0007445700 -7.831966e-04 -8.243515e-04 -8.682213e-04
## ASV0186     -0.0094251413 -9.730973e-03 -1.004218e-02 -1.035858e-02
## ASV0370      0.0046169303  4.764233e-03  4.915171e-03  5.069854e-03
## ASV0018      0.0060005718  6.201130e-03  6.406092e-03  6.615435e-03
## ASV1377      0.0508376630  5.224653e-02  5.367211e-02  5.511376e-02
## ASV0019      0.0063567228  6.572125e-03  6.792506e-03  7.017864e-03
## ASV0023     -0.0045930159 -4.769366e-03 -4.950805e-03 -5.137356e-03
## ASV2194      0.0083351378  8.705779e-03  9.091609e-03  9.493126e-03
## ASV1155      0.0225508662  2.328910e-02  2.404740e-02  2.482633e-02
## ASV0510     -0.0042855883 -4.373082e-03 -4.461816e-03 -4.551957e-03
## ASV2371     -0.0131662928 -1.355825e-02 -1.395665e-02 -1.436132e-02
## ASV0024     -0.0056566882 -5.872935e-03 -6.095471e-03 -6.324342e-03
## ASV2452      0.0097976214  9.939727e-03  1.007476e-02  1.020224e-02
## ASV2332     -0.0406493983 -4.200417e-02 -4.339409e-02 -4.481972e-02
## ASV2591      0.0167473668  1.742690e-02  1.812465e-02  1.884048e-02
## ASV0521      0.0116871008  1.215313e-02  1.263502e-02  1.313312e-02
## ASV5542      0.0107329005  1.113512e-02  1.154951e-02  1.197629e-02
## ASV0336     -0.0028726635 -3.030049e-03 -3.195153e-03 -3.368311e-03
## ASV10102     0.0198848544  2.062494e-02  2.138544e-02  2.216646e-02
## ASV16823    -0.0208866677 -2.143692e-02 -2.199426e-02 -2.255857e-02
## ASV3104      0.1080690581  1.109157e-01  1.137990e-01  1.167184e-01
## ASV0781      0.0200600526  2.078020e-02  2.152227e-02  2.228684e-02
## ASV10899     0.0197383086  2.071256e-02  2.172962e-02  2.279091e-02
## ASV11222    -0.0367611015 -3.772929e-02 -3.870991e-02 -3.970279e-02
## ASV11327    -0.0330040650 -3.387321e-02 -3.475350e-02 -3.564477e-02
## ASV12458    -0.0367591061 -3.772703e-02 -3.870736e-02 -3.969991e-02
## ASV1636      0.0240291425  2.476026e-02  2.550581e-02  2.626585e-02
## ASV1890     -0.0138077908 -1.409036e-02 -1.437483e-02 -1.466139e-02
## ASV2898      0.0324356720  3.343043e-02  3.444544e-02  3.548088e-02
## ASV8328      0.0167151675  1.772554e-02  1.878690e-02  1.990098e-02
## ASV0709     -0.0383646904 -3.958844e-02 -4.083721e-02 -4.211091e-02
## ASV0856      0.0416254814  4.331239e-02  4.505464e-02  4.685310e-02
## ASV0909      0.0198892761  2.092430e-02  2.200490e-02  2.313237e-02
## ASV0937     -0.0287692872 -2.999651e-02 -3.127292e-02 -3.260022e-02
## ASV11390    -0.0524599012 -5.384085e-02 -5.523946e-02 -5.665546e-02
## ASV11966     0.0218879381  2.279575e-02  2.373297e-02  2.469991e-02
## ASV12990     0.0099514473  1.023343e-02  1.052050e-02  1.081273e-02
## ASV14797     0.0142493250  1.464218e-02  1.504151e-02  1.544738e-02
## ASV14904    -0.0752761513 -7.725743e-02 -7.926401e-02 -8.129553e-02
## ASV15304     0.0156511278  1.634044e-02  1.705345e-02  1.779044e-02
## ASV16696    -0.0260087235 -2.669322e-02 -2.738646e-02 -2.808832e-02
## ASV1690      0.0681446353  7.070979e-02  7.334152e-02  7.603958e-02
## ASV2029      0.0381346879  3.940733e-02  4.071154e-02  4.204767e-02
## ASV2834      0.0541890603  5.615386e-02  5.817024e-02  6.023838e-02
## ASV4003      0.0597620607  6.262025e-02  6.561010e-02  6.873714e-02
## ASV4064      0.0266496619  2.765743e-02  2.869585e-02  2.976551e-02
## ASV4294      0.0231732960  2.430062e-02  2.547731e-02  2.670502e-02
## ASV4609      0.0130380372  1.349942e-02  1.397559e-02  1.446700e-02
## ASV6283     -0.0243117805 -2.495155e-02 -2.559948e-02 -2.625546e-02
## ASV6491     -0.0348458157 -3.576275e-02 -3.669139e-02 -3.763157e-02
## ASV7453      0.0298731584  3.113846e-02  3.244635e-02  3.379740e-02
## ASV7959      0.0154460636  1.624479e-02  1.708013e-02  1.795339e-02
## ASV8219      0.3011382544  3.090622e-01  3.170872e-01  3.252120e-01
## ASV8547     -0.0311968541 -3.201773e-02 -3.284910e-02 -3.369079e-02
## ASV9319      0.0220626477  2.299890e-02  2.397137e-02  2.498124e-02
## ASV9382     -0.0610404175 -6.264656e-02 -6.427322e-02 -6.592011e-02
## ASV11516    -0.0407698978 -4.184268e-02 -4.292916e-02 -4.402917e-02
## ASV14377    -0.0294379706 -3.021258e-02 -3.099710e-02 -3.179139e-02
## ASV1867      0.0340087963  3.534277e-02  3.672160e-02  3.814644e-02
## ASV1895      0.0089153295  8.987529e-03  9.047459e-03  9.094326e-03
## ASV3168      0.0141782823  1.450403e-02  1.482964e-02  1.515481e-02
## ASV4449      0.1072994001  1.112711e-01  1.153690e-01  1.195964e-01
## ASV6596      0.0324769596  3.402177e-02  3.563316e-02  3.731329e-02
## ASV7492      0.0043042663  4.712814e-03  5.145007e-03  5.601567e-03
## ASV9854     -0.0059866814 -6.136081e-03 -6.286796e-03 -6.438756e-03
## ASV6296      0.4939884277  5.069877e-01  5.201534e-01  5.334833e-01
## ASV4201      0.0129910641  1.380529e-02  1.466364e-02  1.556797e-02
## ASV0552      0.0226657047  2.350233e-02  2.436162e-02  2.524363e-02
## ASV3671     -0.0148190352 -1.544768e-02 -1.610471e-02 -1.679152e-02
## ASV3529      0.0019138561  2.109021e-03  2.312531e-03  2.524314e-03
## ASV1060      0.0075798817  7.940770e-03  8.318622e-03  8.714180e-03
## ASV0239     -0.0049592780 -5.054568e-03 -5.148494e-03 -5.240872e-03
## ASV5711     -0.0313345849 -3.237348e-02 -3.343775e-02 -3.452758e-02
## ASV4152     -0.0500491321 -5.185618e-02 -5.371135e-02 -5.561483e-02
## ASV1461      0.0166044263  1.694699e-02  1.728737e-02  1.762520e-02
## ASV2877      0.0089525436  9.135214e-03  9.314990e-03  9.491418e-03
## ASV0012      0.0022325704  2.314158e-03  2.398163e-03  2.484626e-03
## ASV9823     -0.0007395950 -9.246174e-04 -1.125113e-03 -1.341862e-03
## ASV0008      0.0023232929  2.406964e-03  2.493095e-03  2.581730e-03
## ASV7832     -0.0312611238 -3.247676e-02 -3.373152e-02 -3.502610e-02
## ASV1915     -0.0037378994 -3.901057e-03 -4.071787e-03 -4.250406e-03
## ASV0055     -0.0040103214 -4.206542e-03 -4.411395e-03 -4.625174e-03
## ASV0032      0.0004078321  4.023378e-04  3.962680e-04  3.896853e-04
## ASV2977     -0.0405440540 -4.196571e-02 -4.342222e-02 -4.491349e-02
## ASV0466      0.0219261908  2.235496e-02  2.277712e-02  2.319189e-02
## ASV3866      0.0260587769  2.714631e-02  2.827522e-02  2.944684e-02
## ASV0040      0.0084963756  8.813950e-03  9.140950e-03  9.477509e-03
## ASV0496     -0.0063990070 -6.771806e-03 -7.161777e-03 -7.569313e-03
## ASV0052      0.0071988327  7.472784e-03  7.755577e-03  8.047437e-03
## ASV3828     -0.0172333397 -1.767415e-02 -1.811967e-02 -1.856978e-02
## ASV1930      0.0092827904  9.507368e-03  9.732186e-03  9.957033e-03
## ASV2126      0.0192202654  1.987547e-02  2.054850e-02  2.123970e-02
## ASV0793      0.0282202359  2.932824e-02  3.047292e-02  3.165514e-02
## ASV0299     -0.0015494032 -1.676342e-03 -1.813478e-03 -1.961494e-03
## ASV0208      0.0195368862  2.029730e-02  2.108389e-02  2.189742e-02
## ASV0511     -0.0047285808 -4.824856e-03 -4.921976e-03 -5.020079e-03
## ASV1123     -0.0155394527 -1.586972e-02 -1.619697e-02 -1.652047e-02
## ASV0099      0.0015249173  1.617509e-03  1.715330e-03  1.818607e-03
## ASV0752     -0.0161973652 -1.689154e-02 -1.761216e-02 -1.836003e-02
## ASV0883      0.0213209644  2.217767e-02  2.306112e-02  2.397153e-02
## ASV0683      0.0271306612  2.823109e-02  2.936926e-02  3.054598e-02
## ASV4117     -0.0401918891 -4.177460e-02 -4.341171e-02 -4.510461e-02
## ASV2172      0.0001876186  1.070587e-04  1.848104e-05 -7.859012e-05
## ASV0330     -0.0077586507 -8.072563e-03 -8.398026e-03 -8.735419e-03
## ASV0728      0.0332988645  3.444812e-02  3.562745e-02  3.683731e-02
## ASV0499      0.0108888217  1.134364e-02  1.181490e-02  1.230301e-02
## ASV0120     -0.0147323092 -1.522327e-02 -1.572438e-02 -1.623549e-02
## ASV1446      0.0037494739  3.603389e-03  3.436178e-03  3.246577e-03
## ASV17171    -0.0303644401 -3.153406e-02 -3.274396e-02 -3.399529e-02
## ASV0533      0.0031154609  3.257205e-03  3.404373e-03  3.557078e-03
## ASV2495     -0.0124624139 -1.309605e-02 -1.375704e-02 -1.444604e-02
## ASV5582      0.0066685956  6.681253e-03  6.681862e-03  6.669588e-03
## ASV1488      0.0036555609  3.713241e-03  3.766979e-03  3.816338e-03
## ASV0682      0.0080288536  8.360848e-03  8.704109e-03  9.058825e-03
## ASV0068     -0.0113907056 -1.177261e-02 -1.216197e-02 -1.255856e-02
## ASV1987     -0.0360438835 -3.757735e-02 -3.916635e-02 -4.081218e-02
## ASV0035     -0.0058771194 -6.250817e-03 -6.646693e-03 -7.065841e-03
## ASV7192     -0.0157187708 -1.619931e-02 -1.668745e-02 -1.718288e-02
## ASV0873     -0.0442315767 -4.693543e-02 -4.975658e-02 -5.269701e-02
## ASV4749     -0.0098636554 -1.053531e-02 -1.124289e-02 -1.198762e-02
## ASV2174      0.0064719162  6.499168e-03  6.516103e-03  6.522126e-03
## ASV1476     -0.0160465919 -1.675055e-02 -1.748185e-02 -1.824123e-02
## ASV0740     -0.0438566806 -4.572949e-02 -4.767468e-02 -4.969455e-02
## ASV0170     -0.0073593317 -7.636282e-03 -7.922084e-03 -8.216958e-03
## ASV2466     -0.0343489230 -3.567874e-02 -3.705274e-02 -3.847196e-02
## ASV1709      0.0119656365  1.249677e-02  1.305618e-02  1.364567e-02
## ASV6170     -0.0576105652 -5.993025e-02 -6.232925e-02 -6.480926e-02
## ASV3673      0.0297254818  3.096110e-02  3.224030e-02  3.356402e-02
## ASV1745     -0.0091250928 -9.545704e-03 -9.983130e-03 -1.043781e-02
##                                                                    
## (Intercept)  1.950955e-01  0.2015597410  0.2081650271  0.2149107921
## ASV1236      3.196585e-02  0.0328849621  0.0338199336  0.0347707003
## ASV0421      8.997843e-03  0.0094151946  0.0098459274  0.0102900360
## ASV0691     -1.545344e-02 -0.0156445603 -0.0158298043 -0.0160090441
## ASV0899      2.667693e-02  0.0273687708  0.0280678190  0.0287739366
## ASV1004      6.360299e-02  0.0653775228  0.0671788241  0.0690066156
## ASV1041     -2.286916e-02 -0.0233150353 -0.0237523260 -0.0241800474
## ASV1058      4.001640e-02  0.0411670416  0.0423382178  0.0435299412
## ASV12542     1.386518e-02  0.0142364786  0.0146152732  0.0150018044
## ASV1294      3.775168e-02  0.0388675407  0.0400063417  0.0411684063
## ASV13113     2.103227e-02  0.0219791485  0.0229645478  0.0239896689
## ASV1318      3.689647e-02  0.0379422231  0.0390060042  0.0400879175
## ASV2269     -6.067931e-02 -0.0622059728 -0.0637423463 -0.0652874716
## ASV2542      4.386826e-02  0.0456036165  0.0473978932  0.0492524678
## ASV2660     -2.384735e-02 -0.0244603008 -0.0250797910 -0.0257056763
## ASV2737      6.922694e-03  0.0070889581  0.0072585186  0.0074315108
## ASV2840      2.623112e-02  0.0267006101  0.0271634791  0.0276192201
## ASV3053      1.576650e-01  0.1617824283  0.1659618830  0.1702035790
## ASV3077      1.059789e-02  0.0109036835  0.0112162913  0.0115358512
## ASV3134      3.116383e-02  0.0325098788  0.0339082490  0.0353604778
## ASV3140      3.256777e-02  0.0336614879  0.0347802102  0.0359239448
## ASV3579      1.756792e-02  0.0183540802  0.0191684004  0.0200112513
## ASV6119     -1.659574e-02 -0.0170133481 -0.0174338299 -0.0178569740
## ASV7557     -3.372386e-02 -0.0345727686 -0.0354276479 -0.0362880754
## ASV8422      8.336529e-03  0.0085782415  0.0088258886  0.0090796535
## ASV1086     -9.745688e-04 -0.0010060242 -0.0010392289 -0.0010742702
## ASV1310      1.657747e-02  0.0170185714  0.0174644430  0.0179148527
## ASV15750    -1.215459e-03 -0.0012048125 -0.0011911861 -0.0011744587
## ASV16905    -6.934773e-03 -0.0071096928 -0.0072859279 -0.0074633995
## ASV2033      4.434621e-02  0.0460378325  0.0477800862  0.0495737695
## ASV2089      1.466074e-02  0.0150300925  0.0154021134  0.0157766302
## ASV2127      4.980770e-02  0.0512139676  0.0526438416  0.0540973088
## ASV2725      3.604664e-02  0.0369334320  0.0378279233  0.0387298089
## ASV2804     -1.435755e-02 -0.0147202370 -0.0150857455 -0.0154539159
## ASV3075      4.221339e-02  0.0438280370  0.0454991772  0.0472284520
## ASV3327      6.136429e-02  0.0636266748  0.0659542844  0.0683480841
## ASV3342      5.193490e-02  0.0538652489  0.0558546833  0.0579044033
## ASV3532     -5.525296e-02 -0.0573180710 -0.0594533559 -0.0616611600
## ASV3600      2.569566e-02  0.0266181980  0.0275664728  0.0285407937
## ASV4013      4.112618e-02  0.0423726540  0.0436410940  0.0449311559
## ASV4136      3.829507e-02  0.0393515569  0.0404259618  0.0415183636
## ASV4195      1.466008e-01  0.1503109561  0.1540509877  0.1578191571
## ASV4407     -5.664807e-02 -0.0580824285 -0.0595283865 -0.0609852781
## ASV4717      7.518641e-03  0.0076865256  0.0078580175  0.0080333628
## ASV6794      2.209200e-02  0.0226940383  0.0233084588  0.0239355518
## ASV8324     -2.907280e-02 -0.0298098445 -0.0305529423 -0.0313017400
## ASV8981      2.192574e-03  0.0023693943  0.0025559288  0.0027524527
## ASV9859      2.293746e-02  0.0241215257  0.0253628042  0.0266635917
## ASV0936      3.757027e-02  0.0388491592  0.0401570184  0.0414937711
## ASV12683    -3.947851e-04 -0.0003966124 -0.0003965836 -0.0003945089
## ASV1293      1.899226e-02  0.0194945974  0.0200031207  0.0205177210
## ASV13055     1.571749e-03  0.0016948459  0.0018246448  0.0019613656
## ASV17063    -1.509288e-02 -0.0154760481 -0.0158623577 -0.0162515992
## ASV2228      1.230995e-02  0.0126225497  0.0129377111  0.0132552610
## ASV2769      4.359012e-03  0.0045421415  0.0047296637  0.0049214397
## ASV2803      1.121166e-02  0.0114607272  0.0117120341  0.0119656427
## ASV2896      1.680823e-02  0.0175393695  0.0183013368  0.0190953529
## ASV3062      2.294395e-02  0.0239159700  0.0249203247  0.0259574215
## ASV3107      2.826708e-02  0.0293523369  0.0304725619  0.0316284562
## ASV3265      2.664888e-02  0.0273352204  0.0280288831  0.0287296356
## ASV3666     -3.280266e-04 -0.0003615549 -0.0003970789 -0.0004346379
## ASV4497      1.001499e-02  0.0103070548  0.0106043655  0.0109069302
## ASV6914     -3.218266e-03 -0.0033651971 -0.0035172733 -0.0036745524
## ASV0576     -2.548700e-02 -0.0259696685 -0.0264498818 -0.0269273237
## ASV0673      4.032102e-02  0.0415499274  0.0428044221  0.0440847750
## ASV0772      2.037369e-02  0.0210724936  0.0217911067  0.0225299822
## ASV0862      8.248722e-03  0.0086646546  0.0090936659  0.0095356021
## ASV0898      1.950768e-02  0.0202414252  0.0209957727  0.0217709451
## ASV0910      2.153966e-02  0.0223665548  0.0232197364  0.0240997200
## ASV0964     -1.027042e-02 -0.0104842117 -0.0106982968 -0.0109126485
## ASV10059     1.795703e-02  0.0187130102  0.0194953886  0.0203046849
## ASV10263    -2.299040e-02 -0.0235755906 -0.0241655878 -0.0247600332
## ASV1088      3.815707e-02  0.0396735393  0.0412444327  0.0428713389
## ASV1101      3.256616e-02  0.0334034749  0.0342496142  0.0351043482
## ASV1183      1.135752e-02  0.0117654646  0.0121858730  0.0126190587
## ASV11956     6.803209e-03  0.0069590052  0.0071175628  0.0072790600
## ASV12774    -1.696237e-03 -0.0018172102 -0.0019438578 -0.0020762759
## ASV1321      5.732516e-02  0.0595265570  0.0617935053  0.0641266917
## ASV13793    -1.585499e-02 -0.0162586252 -0.0166655636 -0.0170755559
## ASV14482     9.245898e-04  0.0009652156  0.0010082635  0.0010538703
## ASV15483     8.973398e-03  0.0092950335  0.0096254089  0.0099646548
## ASV2062      3.561476e-02  0.0367631539  0.0379389471  0.0391424438
## ASV2132      3.391338e-02  0.0351256723  0.0363698824  0.0376462082
## ASV2413      2.555195e-02  0.0263267081  0.0271188023  0.0279285415
## ASV2490      6.661369e-02  0.0682195311  0.0698393620  0.0714727606
## ASV2594      1.312334e-02  0.0136658191  0.0142297880  0.0148160137
## ASV2822     -4.183614e-02 -0.0429015486 -0.0439757131 -0.0450580125
## ASV2863      4.461857e-02  0.0458397418  0.0470804423  0.0483406403
## ASV2910      1.670958e-02  0.0171753651  0.0176491891  0.0181311263
## ASV2980      2.110111e-02  0.0217595920  0.0224319261  0.0231181663
## ASV3307      3.329728e-02  0.0341455116  0.0350007957  0.0358626752
## ASV3474      3.440945e-02  0.0357749863  0.0371837687  0.0386364237
## ASV3502      2.957413e-02  0.0306177687  0.0316922171  0.0327982292
## ASV4236      2.953431e-02  0.0301704983  0.0308081012  0.0314468897
## ASV4842     -3.596892e-03 -0.0036389320 -0.0036758322 -0.0037072026
## ASV4894     -1.586056e-02 -0.0162648460 -0.0166725481 -0.0170834666
## ASV5290      1.673829e-02  0.0173291309  0.0179365068  0.0185607695
## ASV5501      1.128059e-02  0.0117659897  0.0122724871  0.0128009417
## ASV5795      1.157260e-02  0.0119847726  0.0124075741  0.0128410422
## ASV5987     -4.430234e-02 -0.0454324706 -0.0465723668 -0.0477215074
## ASV6267     -4.992534e-02 -0.0511993420 -0.0524844634 -0.0537801379
## ASV6862      1.915586e-02  0.0196618615  0.0201759139  0.0206980846
## ASV7145      8.915881e-03  0.0092033483  0.0094998422  0.0098056396
## ASV7673     -1.586527e-02 -0.0162704312 -0.0166791944 -0.0170913877
## ASV7789      1.642776e-02  0.0172113638  0.0180276817  0.0188776652
## ASV7809      3.214219e-03  0.0033893007  0.0035710430  0.0037594927
## ASV8002     -2.004161e-02 -0.0205541031 -0.0210712908 -0.0215929810
## ASV8205      1.136977e-02  0.0117864278  0.0122151418  0.0126560496
## ASV9155     -4.225376e-03 -0.0042984748 -0.0043699644 -0.0044397241
## ASV9221      7.600860e-03  0.0080270459  0.0084734123  0.0089406333
## ASV9311     -3.216354e-02 -0.0329878546 -0.0338200559 -0.0346598784
## ASV9557     -2.198542e-02 -0.0225492953 -0.0231186369 -0.0236932682
## ASV9936     -4.434513e-02 -0.0454833615 -0.0466327604 -0.0477929896
## ASV1445      3.567685e-02  0.0369330512  0.0382221952  0.0395445316
## ASV4232      1.899413e-02  0.0199115361  0.0208721343  0.0218777290
## ASV6479      1.161136e-02  0.0122523509  0.0129239614  0.0136272174
## ASV0142     -1.907394e-02 -0.0195878474 -0.0201094098 -0.0206386095
## ASV0378      1.411971e-02  0.0146711740  0.0152376573  0.0158190856
## ASV1122      3.620862e-02  0.0375509316  0.0389334362  0.0403568272
## ASV0123     -1.660822e-02 -0.0170447952 -0.0174870308 -0.0179348555
## ASV2064      5.221200e-03  0.0052085542  0.0051849100  0.0051496501
## ASV4459     -6.416624e-04 -0.0006683115 -0.0006983837 -0.0007322402
## ASV0448      1.153603e-02  0.0120082892  0.0124959413  0.0129991974
## ASV0397      1.838835e-02  0.0189784842  0.0195816248  0.0201978414
## ASV0485      2.022262e-02  0.0208502919  0.0214914557  0.0221461990
## ASV1566      3.115558e-02  0.0321494327  0.0331648905  0.0342020047
## ASV1365      2.756978e-02  0.0284389633  0.0293238701  0.0302242649
## ASV1065      4.015836e-02  0.0415119882  0.0428984085  0.0443178084
## ASV0722     -3.113807e-03 -0.0032711792 -0.0034364722 -0.0036100303
## ASV12660    -1.759494e-02 -0.0180427690 -0.0184955609 -0.0189532281
## ASV0223      5.925741e-03  0.0061292882  0.0063389235  0.0065548157
## ASV0229      1.077316e-02  0.0111930201  0.0116274455  0.0120768718
## ASV0877     -5.832475e-05 -0.0002530732 -0.0004675058 -0.0007028425
## ASV0983      1.886651e-02  0.0193957662  0.0199324121  0.0204762557
## ASV0626      6.307435e-03  0.0066155424  0.0069345333  0.0072645414
## ASV4146     -1.006202e-03 -0.0011787899 -0.0013679839 -0.0015748340
## ASV4175     -2.927984e-02 -0.0303103499 -0.0313670599 -0.0324500748
## ASV2082     -2.465891e-02 -0.0259362127 -0.0272708349 -0.0286644497
## ASV2272      1.435607e-02  0.0149025205  0.0154668179  0.0160493872
## ASV2245     -2.144665e-02 -0.0222130024 -0.0229991576 -0.0238051836
## ASV0590     -2.534251e-02 -0.0266705773 -0.0280585984 -0.0295084254
## ASV0217      7.322746e-03  0.0077488236  0.0081937500  0.0086580189
## ASV0416      6.799400e-03  0.0067833432  0.0067548255  0.0067132992
## ASV1056      2.222191e-02  0.0230524552  0.0239057438  0.0247818827
## ASV7777     -2.912241e-02 -0.0302455251 -0.0314097716 -0.0326167843
## ASV0455      4.534779e-03  0.0046682683  0.0048031375  0.0049392277
## ASV0604      1.560473e-02  0.0162225824  0.0168599163  0.0175170350
## ASV6100     -2.170583e-02 -0.0225918663 -0.0235119605 -0.0244673551
## ASV11359    -4.043662e-02 -0.0417816199 -0.0431550002 -0.0445564480
## ASV6604      6.660956e-03  0.0069110596  0.0071671918  0.0074292031
## ASV5004     -1.461984e-02 -0.0151539603 -0.0157052769 -0.0162742649
## ASV1483     -5.763123e-03 -0.0059435218 -0.0061271732 -0.0063139793
## ASV9773     -1.983230e-02 -0.0205908536 -0.0213748821 -0.0221850929
## ASV4059      5.053520e-03  0.0053609240  0.0056802461  0.0060114016
## ASV1193      2.098266e-02  0.0216812439  0.0223969263  0.0231298461
## ASV4610      1.901493e-03  0.0020653760  0.0022338583  0.0024066245
## ASV0742      2.905813e-03  0.0031173680  0.0033368235  0.0035640913
## ASV1502     -4.387407e-03 -0.0046200471 -0.0048609701 -0.0051101676
## ASV0195     -1.468402e-03 -0.0015717551 -0.0016799661 -0.0017931502
## ASV1213      9.625971e-03  0.0097936980  0.0099584980  0.0101201102
## ASV1648     -1.963475e-02 -0.0204507300 -0.0212992301 -0.0221814529
## ASV6984     -1.869203e-02 -0.0194816859 -0.0203034771 -0.0211586098
## ASV0396      5.832555e-04  0.0005973320  0.0006072646  0.0006123944
## ASV4297      1.571809e-02  0.0160806651  0.0164460463  0.0168142711
## ASV2622      2.873475e-02  0.0295626037  0.0304053157  0.0312629237
## ASV3512      2.265796e-02  0.0237874116  0.0249688118  0.0262041052
## ASV2411      2.862917e-02  0.0297577232  0.0309208911  0.0321189578
## ASV2291     -2.202420e-02 -0.0231381217 -0.0242975108 -0.0255033711
## ASV0807      3.007175e-02  0.0310135577  0.0319740683  0.0329532965
## ASV1292      4.108559e-03  0.0041679255  0.0042276072  0.0042878708
## ASV1035      2.412362e-02  0.0248385415  0.0255695587  0.0263170270
## ASV0070      2.962509e-03  0.0031526934  0.0033525072  0.0035622512
## ASV0255      6.335256e-04  0.0005575175  0.0004722106  0.0003769924
## ASV0057     -4.787427e-03 -0.0048490812 -0.0049071267 -0.0049613256
## ASV0077     -2.657213e-04 -0.0002444409 -0.0002225709 -0.0002002901
## ASV0625      1.234928e-02  0.0126420224  0.0129365937  0.0132328808
## ASV2464      8.562195e-02  0.0877919842  0.0899866854  0.0922055411
## ASV1315      3.820634e-02  0.0397403188  0.0413233303  0.0429560060
## ASV2673      3.318833e-02  0.0345454871  0.0359487329  0.0373989762
## ASV2161      1.429034e-02  0.0149018589  0.0155368231  0.0161959100
## ASV0337     -6.908073e-03 -0.0071654334 -0.0074308017 -0.0077043540
## ASV7680     -4.634614e-02 -0.0480862695 -0.0498784330 -0.0517233169
## ASV0611      2.655304e-02  0.0275944508  0.0286713389  0.0297846283
## ASV3118     -3.099775e-02 -0.0322663344 -0.0335772586 -0.0349312431
## ASV1284     -9.436533e-03 -0.0103977452 -0.0114231003 -0.0125155989
## ASV0889      1.591784e-02  0.0164536325  0.0170060135  0.0175756215
## ASV4649     -9.137755e-03 -0.0094688576 -0.0098099273 -0.0101611660
## ASV1108     -2.547939e-02 -0.0265968338 -0.0277557866 -0.0289571669
## ASV0738      1.840852e-02  0.0193421505  0.0203187640  0.0213399684
## ASV0473     -3.866662e-03 -0.0040069211 -0.0041468307 -0.0042857520
## ASV0598     -1.116555e-02 -0.0117706157 -0.0124046737 -0.0130687204
## ASV0429      9.389459e-03  0.0095877523  0.0097844752  0.0099793634
## ASV1549      3.083733e-02  0.0320905765  0.0333841888  0.0347186070
## ASV1203      1.668020e-02  0.0171679372  0.0176632709  0.0181660240
## ASV4532      3.079545e-04  0.0003321632  0.0003599736  0.0003917748
## ASV0274      4.414112e-03  0.0045662594  0.0047197458  0.0048742257
## ASV0163     -1.115771e-02 -0.0114692721 -0.0117880622 -0.0121143728
## ASV1298      1.568775e-03  0.0016811314  0.0018038363  0.0019376914
## ASV9424     -3.830382e-02 -0.0398680733 -0.0414901398 -0.0431717698
## ASV0412      2.825092e-02  0.0290787589  0.0299214717  0.0307790481
## ASV0284      1.794908e-03  0.0016795084  0.0015501836  0.0014061106
## ASV0620     -1.206582e-02 -0.0126428809 -0.0132432632 -0.0138675698
## ASV0153     -4.042129e-02 -0.0420272766 -0.0436827040 -0.0453880612
## ASV0498      1.162744e-02  0.0119842734  0.0123447149  0.0127082867
## ASV0097      8.105498e-03  0.0084349378  0.0087749495  0.0091256413
## ASV0104     -4.084771e-02 -0.0420815968 -0.0433363175 -0.0446115073
## ASV1282      9.807861e-03  0.0099125537  0.0100041465  0.0100815398
## ASV3883     -1.785196e-02 -0.0185941887 -0.0193585695 -0.0201450617
## ASV0801      7.106754e-03  0.0074057138  0.0077176784  0.0080432633
## ASV1611     -3.529618e-02 -0.0367201481 -0.0381921419 -0.0397130950
## ASV0227     -1.036710e-02 -0.0108814556 -0.0114173855 -0.0119755030
## ASV0833      1.030972e-02  0.0106713701  0.0110424250  0.0114229791
## ASV0718      4.635397e-02  0.0480144952  0.0497204907  0.0514724442
## ASV1139     -1.196926e-03 -0.0014601498 -0.0017416804 -0.0020421381
## ASV0766     -8.956747e-03 -0.0093320547 -0.0097189826 -0.0101175696
## ASV2091      2.544324e-02  0.0260047638  0.0265655550  0.0271251108
## ASV1238     -4.109860e-02 -0.0429088734 -0.0447970564 -0.0467662382
## ASV9193     -1.033250e-02 -0.0109512942 -0.0116022384 -0.0122865132
## ASV0290      1.925452e-03  0.0019596278  0.0019968054  0.0020374052
## ASV0231      1.064834e-02  0.0109199975  0.0111921946  0.0114645060
## ASV0185      1.386277e-02  0.0145566044  0.0152813252  0.0160379547
## ASV2330      9.843258e-03  0.0100574471  0.0102736353  0.0104919527
## ASV3119     -1.201061e-02 -0.0125960157 -0.0132065112 -0.0138428707
## ASV2368     -2.342086e-02 -0.0245027314 -0.0256318740 -0.0268099961
## ASV0122     -7.303522e-03 -0.0075313442 -0.0077640987 -0.0080018411
## ASV1044      2.564061e-02  0.0266962532  0.0277901529  0.0289233658
## ASV0160     -6.069856e-03 -0.0062251673 -0.0063841621 -0.0065471024
## ASV0326      2.137411e-03  0.0021910288  0.0022438952  0.0022958123
## ASV1388      3.797729e-02  0.0391292590  0.0403019483  0.0414951698
## ASV0792      2.442157e-02  0.0250475750  0.0256792156  0.0263162102
## ASV0036     -1.186015e-02 -0.0123104425 -0.0127724439 -0.0132460623
## ASV2125      2.819661e-02  0.0290747778  0.0299687786  0.0308783285
## ASV1075     -8.672829e-04 -0.0009258197 -0.0009884532 -0.0010554178
## ASV0390      2.154463e-02  0.0225009298  0.0234964274  0.0245324269
## ASV3790     -2.543567e-02 -0.0264006379 -0.0273958830 -0.0284219921
## ASV1535     -1.079714e-02 -0.0112898784 -0.0118003941 -0.0123289271
## ASV0263      2.847669e-02  0.0294670057  0.0304830604  0.0315250693
## ASV0675      4.896521e-02  0.0508704748  0.0528364213  0.0548641238
## ASV3348      4.831768e-03  0.0050328296  0.0052399776  0.0054532086
## ASV0058     -1.097274e-02 -0.0112935251 -0.0116191433 -0.0119494835
## ASV4142      1.326320e-02  0.0136030837  0.0139476398  0.0142969520
## ASV0059     -8.429895e-03 -0.0086626348 -0.0088981948 -0.0091364814
## ASV0013     -1.774418e-02 -0.0183459267 -0.0189626213 -0.0195944085
## ASV0033     -1.025175e-02 -0.0106443332 -0.0110477319 -0.0114619449
## ASV4354     -1.148867e-02 -0.0119316588 -0.0123889979 -0.0128609080
## ASV0022     -8.726314e-03 -0.0090662470 -0.0094160848 -0.0097758662
## ASV0134     -1.029424e-02 -0.0107833183 -0.0112946323 -0.0118291294
## ASV0415      1.993709e-03  0.0020748105  0.0021579210  0.0022430240
## ASV10103    -4.659721e-02 -0.0484144731 -0.0502889944 -0.0522216082
## ASV1613      2.238092e-02  0.0228862257  0.0233886204  0.0238872689
## ASV0135     -2.185929e-03 -0.0022111246 -0.0022344782 -0.0022558757
## ASV0469     -3.468104e-02 -0.0358089701 -0.0369660291 -0.0381528044
## ASV0471      2.326123e-02  0.0240839024  0.0249317494  0.0258055353
## ASV0451     -8.243522e-03 -0.0086520063 -0.0090761795 -0.0095162823
## ASV0747      1.366167e-02  0.0141219005  0.0145917643  0.0150711036
## ASV1314     -1.817897e-02 -0.0189905690 -0.0198351532 -0.0207137660
## ASV0425     -3.620198e-02 -0.0371379310 -0.0380853878 -0.0390442411
## ASV0559     -1.280614e-02 -0.0133397121 -0.0138957010 -0.0144749748
## ASV0148      9.598620e-04  0.0011221311  0.0012964919  0.0014835166
## ASV0129      9.598015e-03  0.0101696142  0.0107701208  0.0114005356
## ASV1072      6.737206e-04  0.0006094456  0.0005386689  0.0004611378
## ASV2390      1.434645e-02  0.0145083226  0.0146568246  0.0147911642
## ASV0548      1.516839e-02  0.0156519612  0.0161455104  0.0166490223
## ASV0168     -7.166534e-03 -0.0073845996 -0.0076072417 -0.0078345064
## ASV0066     -7.963558e-03 -0.0081785685 -0.0083947563 -0.0086118313
## ASV0468     -5.338730e-03 -0.0055465057 -0.0057618556 -0.0059850491
## ASV0172     -6.380501e-04 -0.0005860808 -0.0005284823 -0.0004649802
## ASV0236      7.325703e-03  0.0078208658  0.0083408014  0.0088861661
## ASV0250      2.114685e-02  0.0221716678  0.0232417701  0.0243587272
## ASV0338      6.834441e-03  0.0070540247  0.0072762113  0.0075007157
## ASV0450     -3.021287e-03 -0.0031903961 -0.0033676880 -0.0035534254
## ASV0377      9.928592e-03  0.0101981864  0.0104693459  0.0107416949
## ASV1022      4.340828e-04  0.0005020682  0.0005764108  0.0006575454
## ASV6174     -1.312128e-03 -0.0013796683 -0.0014478691 -0.0015163309
## ASV0786     -4.194037e-03 -0.0043909142 -0.0045932641 -0.0048009145
## ASV0053     -1.273861e-02 -0.0131749996 -0.0136220897 -0.0140799410
## ASV0697     -6.372972e-03 -0.0065704176 -0.0067734539 -0.0069823608
## ASV0785      1.422917e-02  0.0146635300  0.0151070454  0.0155598760
## ASV1967     -1.410953e-02 -0.0145502681 -0.0150003278 -0.0154596842
## ASV0385      6.458159e-03  0.0066824695  0.0069100882  0.0071406905
## ASV0295      3.639601e-03  0.0038590873  0.0040898074  0.0043321663
## ASV0072     -9.524440e-03 -0.0097386302 -0.0099511573 -0.0101616140
## ASV0157      2.680467e-03  0.0029328256  0.0032018818  0.0034883990
## ASV0501      2.762579e-02  0.0285426242  0.0294775042  0.0304300576
## ASV10729    -3.749324e-02 -0.0388899148 -0.0403279509 -0.0418079528
## ASV1470      1.005102e-02  0.0101515486  0.0102403426  0.0103165073
## ASV0050     -2.608434e-02 -0.0268554094 -0.0276385427 -0.0284334633
## ASV0411     -8.311598e-03 -0.0086654378 -0.0090335554 -0.0094165176
## ASV0549      1.211522e-02  0.0125706917  0.0130392977  0.0135211576
## ASV0184      3.737565e-03  0.0038898144  0.0040486788  0.0042144893
## ASV0705      5.236560e-03  0.0053413012  0.0054433859  0.0055424141
## ASV1715      1.506096e-02  0.0155749177  0.0161013810  0.0166404141
## ASV0603      3.561630e-03  0.0037528349  0.0039547531  0.0041679274
## ASV0826      2.390233e-02  0.0246934020  0.0255042900  0.0263352979
## ASV0034     -6.487573e-03 -0.0066555275 -0.0068247190 -0.0069950301
## ASV0838     -5.303425e-03 -0.0059407368 -0.0066271802 -0.0073655156
## ASV0614     -6.480942e-03 -0.0066921784 -0.0069084503 -0.0071298284
## ASV0014     -1.741607e-02 -0.0179775910 -0.0185509746 -0.0191361857
## ASV0585     -4.075814e-03 -0.0043812142 -0.0047001019 -0.0050324974
## ASV0016     -1.822889e-02 -0.0188182929 -0.0194203021 -0.0200349003
## ASV5394     -1.476187e-02 -0.0152613314 -0.0157708157 -0.0162899832
## ASV0666      2.435493e-02  0.0249855035  0.0256226586  0.0262662009
## ASV2085     -3.235746e-03 -0.0036734172 -0.0041399687 -0.0046365727
## ASV0003     -1.240155e-02 -0.0128029377 -0.0132130641 -0.0136319415
## ASV0346      7.831160e-03  0.0081159230  0.0084070071  0.0087042792
## ASV0267      1.664517e-03  0.0017448179  0.0018251330  0.0019049924
## ASV0353      1.243795e-02  0.0129280537  0.0134338055  0.0139554521
## ASV2419      2.526638e-02  0.0260260833  0.0267971799  0.0275791200
## ASV0447      1.825055e-02  0.0189668927  0.0197064583  0.0204697525
## ASV0654      2.153364e-02  0.0222170807  0.0229138243  0.0236237551
## ASV0151      5.669322e-03  0.0059487259  0.0062392937  0.0065412229
## ASV0065     -7.886082e-03 -0.0081273680 -0.0083732955 -0.0086238669
## ASV0527      2.029209e-02  0.0209404075  0.0216018620  0.0222763248
## ASV4055     -6.337216e-03 -0.0067047044 -0.0070944097 -0.0075076382
## ASV0166     -8.405206e-03 -0.0086216875 -0.0088406435 -0.0090620855
## ASV0417     -2.186185e-03 -0.0021932685 -0.0021974257 -0.0021985787
## ASV0078     -4.849240e-03 -0.0049495931 -0.0050477878 -0.0051434864
## ASV0322      2.338622e-03  0.0025733295  0.0028243647  0.0030924473
## ASV0156     -1.723666e-02 -0.0179126326 -0.0186120868 -0.0193357214
## ASV0648     -3.756985e-02 -0.0389961625 -0.0404646565 -0.0419757124
## ASV0407     -3.514654e-03 -0.0036784850 -0.0038495274 -0.0040280456
## ASV2030     -6.658392e-03 -0.0069834423 -0.0073250488 -0.0076838989
## ASV0300      4.964084e-03  0.0051592737  0.0053600896  0.0055665411
## ASV1150      1.528337e-03  0.0015904384  0.0016536396  0.0017178188
## ASV0958      1.675077e-02  0.0174983593  0.0182760733  0.0190848330
## ASV0216     -1.328291e-02 -0.0137892605 -0.0143153930 -0.0148621560
## ASV0446      2.259998e-02  0.0234244078  0.0242707724  0.0251391512
## ASV0367     -1.410204e-02 -0.0146084920 -0.0151288098 -0.0156631231
## ASV0200     -8.047552e-03 -0.0083134345 -0.0085842567 -0.0088598356
## ASV0334     -1.609581e-03 -0.0016192451 -0.0016297276 -0.0016413331
## ASV1311      1.961541e-03  0.0019165673  0.0018639450  0.0018032690
## ASV0458      2.974052e-03  0.0029384669  0.0028953557  0.0028444061
## ASV1371      1.606877e-03  0.0016560215  0.0017048469  0.0017531784
## ASV0418      1.356948e-02  0.0139174612  0.0142689608  0.0146238581
## ASV0004      1.840790e-03  0.0018830616  0.0019254517  0.0019679309
## ASV1943      2.115747e-02  0.0212446397  0.0213115860  0.0213579051
## ASV1495     -1.012912e-02 -0.0107068947 -0.0113126897 -0.0119473902
## ASV0901     -1.849637e-02 -0.0192781237 -0.0200904279 -0.0209343110
## ASV0628      4.233709e-03  0.0042476683  0.0042540531  0.0042523350
## ASV0400      3.340635e-03  0.0033836927  0.0034220613  0.0034552305
## ASV0116     -5.270230e-03 -0.0054837476 -0.0057048224 -0.0059336528
## ASV0788      4.765655e-02  0.0496390692  0.0516966373  0.0538317071
## ASV0117      3.981049e-03  0.0041518629  0.0043287762  0.0045119243
## ASV3137     -6.538948e-04 -0.0006617963 -0.0006683951 -0.0006735124
## ASV0001      1.877294e-03  0.0019170357  0.0019568510  0.0019967456
## ASV1651      5.920346e-03  0.0060735199  0.0062291185  0.0063872448
## ASV1692      3.855730e-02  0.0401049964  0.0417071210  0.0433652374
## ASV0660      4.906820e-03  0.0048361775  0.0047498258  0.0046469703
## ASV0508      1.918353e-04  0.0001823530  0.0001712104  0.0001582481
## ASV1660     -9.597993e-03 -0.0099974915 -0.0104086429 -0.0108313742
## ASV0233      1.045597e-02  0.0108302452  0.0112151142  0.0116107653
## ASV1343     -2.178805e-02 -0.0226668006 -0.0235770289 -0.0245196352
## ASV0209      6.246915e-03  0.0063646844  0.0064799584  0.0065924103
## ASV0193     -7.514748e-03 -0.0076546147 -0.0077907749 -0.0079227848
## ASV0357      8.444376e-03  0.0089087554  0.0093968555  0.0099096412
## ASV0198      7.518320e-03  0.0077702475  0.0080294262  0.0082960587
## ASV0007      1.431267e-03  0.0014522312  0.0014726450  0.0014925060
## ASV1772      6.194958e-04  0.0008756822  0.0011598071  0.0014740787
## ASV0009      9.925896e-04  0.0009989107  0.0010044165  0.0010091172
## ASV0006     -2.961921e-03 -0.0030865062 -0.0032153055 -0.0033483812
## ASV0011     -8.550886e-03 -0.0088755303 -0.0092102699 -0.0095552957
## ASV0015      6.767305e-04  0.0006735844  0.0006689827  0.0006628503
## ASV0017      8.409769e-04  0.0008444922  0.0008468955  0.0008481314
## ASV0235     -8.153960e-03 -0.0084749723 -0.0088071333 -0.0091507768
## ASV0382      5.165572e-03  0.0052804181  0.0053909332  0.0054963882
## ASV2357      2.601733e-02  0.0270270336  0.0280696539  0.0291458149
## ASV0567     -5.943807e-03 -0.0062249642 -0.0065195348 -0.0068281062
## ASV0165      4.103653e-03  0.0042482030  0.0043963517  0.0045481143
## ASV0005      5.177819e-03  0.0053365685  0.0054979323  0.0056618388
## ASV0384      1.597829e-03  0.0017389064  0.0018894691  0.0020500002
## ASV0002      8.679427e-04  0.0008946979  0.0009220792  0.0009500920
## ASV3017      2.156854e-02  0.0220585882  0.0225483844  0.0230374494
## ASV0091     -9.150048e-04 -0.0009649126 -0.0010181676 -0.0010750055
## ASV0186     -1.067995e-02 -0.0110060804 -0.0113367202 -0.0116716144
## ASV0370      5.228402e-03  0.0053909445  0.0055576240  0.0057285937
## ASV0018      6.829133e-03  0.0070471531  0.0072694565  0.0074960005
## ASV1377      5.657082e-02  0.0580426443  0.0595285951  0.0610280412
## ASV0019      7.248193e-03  0.0074834822  0.0077237166  0.0079688769
## ASV0023     -5.329035e-03 -0.0055258501 -0.0057277981 -0.0059348677
## ASV2194      9.910836e-03  0.0103452456  0.0107968688  0.0112662213
## ASV1155      2.562650e-02  0.0264485384  0.0272931376  0.0281610123
## ASV0510     -4.643683e-03 -0.0047371835 -0.0048326566 -0.0049303078
## ASV2371     -1.477208e-02 -0.0151887534 -0.0156111337 -0.0160390088
## ASV0024     -6.559583e-03 -0.0068012205 -0.0070492706 -0.0073037404
## ASV2452      1.032168e-02  0.0104326070  0.0105345628  0.0106270956
## ASV2332     -4.628162e-02 -0.0477803399 -0.0493164239 -0.0508904123
## ASV2591      1.957421e-02  0.0203256187  0.0210944575  0.0218804370
## ASV0521      1.364783e-02  0.0141795182  0.0147285668  0.0152953550
## ASV5542      1.241572e-02  0.0128680286  0.0133334561  0.0138122414
## ASV0336     -3.549872e-03 -0.0037402057 -0.0039396995 -0.0041487616
## ASV10102     2.296811e-02  0.0237904589  0.0246335702  0.0254974735
## ASV16823    -2.312978e-02 -0.0237077705 -0.0242924666 -0.0248837801
## ASV3104      1.196733e-01  0.1226633064  0.1256879346  0.1287467440
## ASV0781      2.307450e-02  0.0238858797  0.0247215855  0.0255822579
## ASV10899     2.389784e-02  0.0250518578  0.0262544018  0.0275069332
## ASV11222    -4.070774e-02 -0.0417246080 -0.0427532285 -0.0437934542
## ASV11327    -3.654688e-02 -0.0374596735 -0.0383830049 -0.0393167424
## ASV12458    -4.070452e-02 -0.0417210113 -0.0427492291 -0.0437890248
## ASV1636      2.704044e-02  0.0278296459  0.0286335190  0.0294521285
## ASV1890     -1.495031e-02 -0.0152418735 -0.0155364049 -0.0158342832
## ASV2898      3.653695e-02  0.0376138394  0.0387117766  0.0398310038
## ASV8328      2.106947e-02  0.0222940677  0.0235764323  0.0249182110
## ASV0709     -4.340947e-02 -0.0447327520 -0.0460806417 -0.0474529860
## ASV0856      4.870859e-02  0.0506218893  0.0525937122  0.0546247213
## ASV0909      2.430796e-02  0.0255329478  0.0268085673  0.0281360540
## ASV0937     -3.398013e-02 -0.0354143905 -0.0369047669 -0.0384530415
## ASV11390    -5.808863e-02 -0.0595387032 -0.0610054726 -0.0624887242
## ASV11966     2.569690e-02  0.0267241972  0.0277820314  0.0288705949
## ASV12990     1.111018e-02  0.0114129471  0.0117210859  0.0120346727
## ASV14797     1.585987e-02  0.0162790653  0.0167050429  0.0171378986
## ASV14904    -8.335164e-02 -0.0854319803 -0.0875362451 -0.0896641323
## ASV15304     1.855169e-02  0.0193374267  0.0201478556  0.0209831471
## ASV16696    -2.879866e-02 -0.0295173803 -0.0302443631 -0.0309795083
## ASV1690      7.880358e-02  0.0816330490  0.0845273591  0.0874857846
## ASV2029      4.341607e-02  0.0448170884  0.0462510400  0.0477182437
## ASV2834      6.235838e-02  0.0645303120  0.0667541791  0.0690299257
## ASV4003      7.200709e-02  0.0754258627  0.0789995426  0.0827344197
## ASV4064      3.086701e-02  0.0320009693  0.0331680036  0.0343687426
## ASV4294      2.798541e-02  0.0293201849  0.0307110307  0.0321596623
## ASV4609      1.497408e-02  0.0154972856  0.0160370498  0.0165938110
## ASV6283     -2.691937e-02 -0.0275911054 -0.0282705653 -0.0289576548
## ASV6491     -3.858311e-02 -0.0395458782 -0.0405197168 -0.0415044963
## ASV7453      3.519217e-02  0.0366311535  0.0381147928  0.0396434834
## ASV7959      1.886589e-02  0.0198189960  0.0208140933  0.0218525903
## ASV8219      3.334351e-01  0.3417552386  0.3501711633  0.3586817566
## ASV8547     -3.454268e-02 -0.0354046231 -0.0362764988 -0.0371581906
## ASV9319      2.602972e-02  0.0271180399  0.0282474483  0.0294192225
## ASV9382     -6.758695e-02 -0.0692734875 -0.0709794722 -0.0727046843
## ASV11516    -4.514251e-02 -0.0462690193 -0.0474085294 -0.0485608964
## ASV14377    -3.259531e-02 -0.0334087407 -0.0342315744 -0.0350637028
## ASV1867      3.961850e-02  0.0411390014  0.0427091833  0.0443303174
## ASV1895      9.127335e-03  0.0091456854  0.0091485781  0.0091352159
## ASV3168      1.547925e-02  0.0158026469  0.0161247074  0.0164451342
## ASV4449      1.239564e-01  0.1284525742  0.1330881925  0.1378667631
## ASV6596      3.906431e-02  0.0408883836  0.0427876588  0.0447642798
## ASV7492      6.083198e-03  0.0065905829  0.0071243823  0.0076852294
## ASV9854     -6.591890e-03 -0.0067461296 -0.0069014097 -0.0070576698
## ASV6296      5.469753e-01  0.5606274213  0.5744377412  0.5884046102
## ASV4201      1.652018e-02  0.0175222233  0.0185760951  0.0196838337
## ASV0552      2.614836e-02  0.0270757897  0.0280258513  0.0289984257
## ASV3671     -1.750949e-02 -0.0182600906 -0.0190448318 -0.0198652618
## ASV3529      2.744266e-03  0.0029722540  0.0032081121  0.0034516438
## ASV1060      9.128211e-03  0.0095615070  0.0100148841  0.0104891837
## ASV0239     -5.331511e-03 -0.0054202125 -0.0055067695 -0.0055909677
## ASV5711     -3.564312e-02 -0.0367845140 -0.0379518653 -0.0391452541
## ASV4152     -5.756671e-02 -0.0595670118 -0.0616156784 -0.0637125833
## ASV1461      1.796012e-02  0.0182917614  0.0186197566  0.0189437480
## ASV2877      9.664026e-03  0.0098323259  0.0099958101  0.0101539532
## ASV0012      2.573589e-03  0.0026650892  0.0027591649  0.0028558522
## ASV9823     -1.575656e-03 -0.0018272977 -0.0020975972 -0.0023873704
## ASV0008      2.672914e-03  0.0027666878  0.0028630936  0.0029621710
## ASV7832     -3.636120e-02 -0.0377374722 -0.0391555814 -0.0406161505
## ASV1915     -4.437241e-03 -0.0046326188 -0.0048368740 -0.0050503440
## ASV0055     -4.848178e-03 -0.0050807111 -0.0053230819 -0.0055756048
## ASV0032      3.826652e-04  0.0003752973  0.0003676858  0.0003599506
## ASV2977     -4.643937e-02 -0.0479996479 -0.0495940699 -0.0512223099
## ASV0466      2.359843e-02  0.0239959467  0.0243836138  0.0247606149
## ASV3866      3.066252e-02  0.0319236591  0.0332316556  0.0345879409
## ASV0040      9.823750e-03  0.0101797905  0.0105457396  0.0109216976
## ASV0496     -7.994784e-03 -0.0084385416 -0.0089009101 -0.0093821888
## ASV0052      8.348596e-03  0.0086592922  0.0089797718  0.0093102871
## ASV3828     -1.902435e-02 -0.0194832617 -0.0199463877 -0.0204136180
## ASV1930      1.018170e-02  0.0104059760  0.0106296632  0.0108525606
## ASV2126      2.194944e-02  0.0226780756  0.0234259843  0.0241935371
## ASV0793      3.287581e-02  0.0341358501  0.0354362032  0.0367778340
## ASV0299     -2.121102e-03 -0.0022930420 -0.0024780790 -0.0026770052
## ASV0208      2.273867e-02  0.0236084256  0.0245074865  0.0254366740
## ASV0511     -5.119323e-03 -0.0052198817 -0.0053219464 -0.0054257245
## ASV1123     -1.683946e-02 -0.0171531003 -0.0174605308 -0.0177608211
## ASV0099      1.927569e-03  0.0020424476  0.0021634770  0.0022908919
## ASV0752     -1.913594e-02 -0.0199407110 -0.0207751601 -0.0216401185
## ASV0883      2.490912e-02  0.0258740569  0.0268664461  0.0278863659
## ASV0683      3.176207e-02  0.0330183144  0.0343154803  0.0356543214
## ASV4117     -4.685467e-02 -0.0486632877 -0.0505318509 -0.0524617536
## ASV2172     -1.846473e-04 -0.0003002000 -0.0004257740 -0.0005619117
## ASV0330     -9.085130e-03 -0.0094475576 -0.0098231129 -0.0102122166
## ASV0728      3.807816e-02  0.0393504817  0.0406547551  0.0419914792
## ASV0499      1.280836e-02  0.0133313598  0.0138724042  0.0144318827
## ASV0120     -1.675639e-02 -0.0172868534 -0.0178266350 -0.0183754473
## ASV1446      3.033287e-03  0.0027949745  0.0025302691  0.0022377686
## ASV17171    -3.528919e-02 -0.0366268032 -0.0380092855 -0.0394377897
## ASV0533      3.715428e-03  0.0038795258  0.0040494700  0.0042253513
## ASV2495     -1.516368e-02 -0.0159105666 -0.0166872832 -0.0174943720
## ASV5582      6.643562e-03  0.0066028729  0.0065465668  0.0064736452
## ASV1488      3.860866e-03  0.0039000898  0.0039335222  0.0039606574
## ASV0682      9.425169e-03  0.0098033018  0.0101933725  0.0105955139
## ASV0068     -1.296214e-02 -0.0133724403 -0.0137891738 -0.0142120167
## ASV1987     -4.251608e-02 -0.0442792756 -0.0461029883 -0.0479883935
## ASV0035     -7.509388e-03 -0.0079784953 -0.0084743521 -0.0089981792
## ASV7192     -1.768527e-02 -0.0181942600 -0.0187094762 -0.0192305091
## ASV0873     -5.575856e-02 -0.0589429197 -0.0622516228 -0.0656860579
## ASV4749     -1.277071e-02 -0.0135933614 -0.0144567761 -0.0153621473
## ASV2174      6.516642e-03  0.0064990544  0.0064687719  0.0064252069
## ASV1476     -1.902945e-02 -0.0198472335 -0.0206953368 -0.0215744980
## ASV0740     -5.179143e-02 -0.0539677020 -0.0562257713 -0.0585680925
## ASV0170     -8.521127e-03 -0.0088348152 -0.0091582532 -0.0094916725
## ASV2466     -3.993741e-02 -0.0414501205 -0.0430110738 -0.0446212580
## ASV1709      1.426712e-02  0.0149225313  0.0156140108  0.0163437694
## ASV6170     -6.737197e-02 -0.0700190298 -0.0727520201 -0.0755724858
## ASV3673      3.493313e-02  0.0363485203  0.0378110040  0.0393213766
## ASV1745     -1.091018e-02 -0.0114006610 -0.0119096917 -0.0124376874
##                                                                    
## (Intercept)  0.2217962628  0.2288204920  2.359824e-01  2.432806e-01
## ASV1236      0.0357371963  0.0367193554  3.771711e-02  3.873041e-02
## ASV0421      0.0107474924  0.0112182476  1.170223e-02  1.219936e-02
## ASV0691     -0.0161821588 -0.0163490312 -1.650955e-02 -1.666359e-02
## ASV0899      0.0294870050  0.0302069296  3.093364e-02  3.166710e-02
## ASV1004      0.0708606167  0.0727405428  7.464611e-02  7.657702e-02
## ASV1041     -0.0245972135 -0.0250028425 -2.539596e-02 -2.577561e-02
## ASV1058      0.0447422228  0.0459750668  4.722847e-02  4.850242e-02
## ASV12542     0.0153963236  0.0157990896  1.621037e-02  1.663043e-02
## ASV1294      0.0423540759  0.0435637085  4.479768e-02  4.605638e-02
## ASV13113     0.0250557221  0.0261639240  2.731550e-02  2.851166e-02
## ASV1318      0.0411880824  0.0423066390  4.344375e-02  4.459960e-02
## ASV2269     -0.0668404300 -0.0684003513 -6.996642e-02 -7.153787e-02
## ASV2542      0.0511687175  0.0531480128  5.519171e-02  5.730117e-02
## ASV2660     -0.0263378326 -0.0269761535 -2.762055e-02 -2.827095e-02
## ASV2737      0.0076080665  0.0077883133  7.972373e-03  8.160364e-03
## ASV2840      0.0280673425  0.0285073750  2.893887e-02  2.936139e-02
## ASV3053      0.1745077424  0.1788745734  1.833042e-01  1.877969e-01
## ASV3077      0.0118625028  0.0121963826  1.253762e-02  1.288636e-02
## ASV3134      0.0368681104  0.0384326943  4.005578e-02  4.173890e-02
## ASV3140      0.0370926795  0.0382863844  3.950501e-02  4.074849e-02
## ASV3579      0.0208829584  0.0217837998  2.271400e-02  2.367375e-02
## ASV6119     -0.0182825763 -0.0187104442 -1.914040e-02 -1.957226e-02
## ASV7557     -0.0371536513 -0.0380239965 -3.889875e-02 -3.977756e-02
## ASV8422      0.0093397242  0.0096062935  9.879560e-03  1.015973e-02
## ASV1086     -0.0011112315 -0.0011501922 -1.191229e-03 -1.234415e-03
## ASV1310      0.0183695601  0.0188283159  1.929086e-02  1.975694e-02
## ASV15750    -0.0011545130 -0.0011312339 -1.104508e-03 -1.074221e-03
## ASV16905    -0.0076420311 -0.0078217480 -8.002475e-03 -8.184137e-03
## ASV2033      0.0514196791  0.0533186146  5.527138e-02  5.727880e-02
## ASV2089      0.0161534713  0.0165324659  1.691344e-02  1.729622e-02
## ASV2127      0.0555743519  0.0570749504  5.859908e-02  6.014670e-02
## ASV2725      0.0396387910  0.0405545804  4.147690e-02  4.240547e-02
## ASV2804     -0.0158245884 -0.0161976014 -1.657279e-02 -1.694997e-02
## ASV3075      0.0490175125  0.0508680141  5.278161e-02  5.475996e-02
## ASV3327      0.0708090266  0.0733380546  7.593610e-02  7.860410e-02
## ASV3342      0.0600156097  0.0621894961  6.442724e-02  6.673002e-02
## ASV3532     -0.0639438947 -0.0663040334 -6.874410e-02 -7.126668e-02
## ASV3600      0.0295414510  0.0305687173  3.162285e-02  3.270408e-02
## ASV4013      0.0462424646  0.0475746159  4.892718e-02  5.029970e-02
## ASV4136      0.0426288421  0.0437574720  4.490432e-02  4.606944e-02
## ASV4195      0.1616137249  0.1654328765  1.692747e-01  1.731371e-01
## ASV4407     -0.0624524105 -0.0639290549 -6.541443e-02 -6.690770e-02
## ASV4717      0.0082128239  0.0083966819  8.585240e-03  8.778824e-03
## ASV6794      0.0245756213  0.0252289837  2.589597e-02  2.657692e-02
## ASV8324     -0.0320558645 -0.0328149188 -3.357847e-02 -3.434607e-02
## ASV8981      0.0029592361  0.0031765442  3.404638e-03  3.643773e-03
## ASV9859      0.0280262334  0.0294531263  3.094672e-02  3.250951e-02
## ASV0936      0.0428593038  0.0442534646  4.567606e-02  4.712686e-02
## ASV12683    -0.0003901853 -0.0003833948 -3.739033e-04 -3.614594e-04
## ASV1293      0.0210382858  0.0215647021  2.209686e-02  2.263464e-02
## ASV13055     0.0021052355  0.0022564905  2.415377e-03  2.582150e-03
## ASV17063    -0.0166435474 -0.0170379608 -1.743458e-02 -1.783313e-02
## ASV2228      0.0135750127  0.0138967663  1.422031e-02  1.454541e-02
## ASV2769      0.0051173209  0.0053171489  5.520757e-03  5.727971e-03
## ASV2803      0.0122216331  0.0124801018  1.274116e-02  1.300494e-02
## ASV2896      0.0199226840  0.0207846408  2.168258e-02  2.261790e-02
## ASV3062      0.0270276438  0.0281313488  2.926887e-02  3.044050e-02
## ASV3107      0.0328207077  0.0340499920  3.531697e-02  3.662229e-02
## ASV3265      0.0294372396  0.0301514526  3.087203e-02  3.159871e-02
## ASV3666     -0.0004742616 -0.0005159693 -5.597699e-04 -6.056618e-04
## ASV4497      0.0112147602  0.0115278713  1.184628e-02  1.217002e-02
## ASV6914     -0.0038370798 -0.0040048887 -4.178000e-03 -4.356422e-03
## ASV0576     -0.0274016890 -0.0278726805 -2.834001e-02 -2.880338e-02
## ASV0673      0.0453912746  0.0467242242  4.808394e-02  4.947076e-02
## ASV0772      0.0232895836  0.0240703833  2.487286e-02  2.569751e-02
## ASV0862      0.0099902691  0.0104574323  1.093682e-02  1.142812e-02
## ASV0898      0.0225671565  0.0233846161  2.422353e-02  2.508410e-02
## ASV0910      0.0250070150  0.0259421228  2.690554e-02  2.789774e-02
## ASV0964     -0.0111272541 -0.0113421169 -1.155725e-02 -1.177270e-02
## ASV10059     0.0211414042  0.0220060373  2.289906e-02  2.382092e-02
## ASV10263    -0.0253585512 -0.0259607499 -2.656623e-02 -2.717457e-02
## ASV1088      0.0445558634  0.0462996275  4.810426e-02  4.997142e-02
## ASV1101      0.0359674529  0.0368387129  3.771792e-02  3.860488e-02
## ASV1183      0.0130653434  0.0135250551  1.399853e-02  1.448611e-02
## ASV11956     0.0074436865  0.0076116423  7.783135e-03  7.958377e-03
## ASV12774    -0.0022145508 -0.0023587599 -2.508973e-03 -2.665253e-03
## ASV1321      0.0665267427  0.0689942187  7.152961e-02  7.413333e-02
## ASV13793    -0.0174883489 -0.0179036842 -1.832130e-02 -1.874095e-02
## ASV14482     0.0011021763  0.0011533236  1.207454e-03  1.264707e-03
## ASV15483     0.0103129053  0.0106702975  1.103697e-02  1.141307e-02
## ASV2062      0.0403739339  0.0416336940  4.292199e-02  4.423906e-02
## ASV2132      0.0389548129  0.0402958274  4.166935e-02  4.307544e-02
## ASV2413      0.0287562492  0.0296022607  3.046692e-02  3.135059e-02
## ASV2490      0.0731193193  0.0747786446  7.645036e-02  7.813410e-02
## ASV2594      0.0154252780  0.0160583768  1.671612e-02  1.739932e-02
## ASV2822     -0.0461478184 -0.0472445037 -4.834745e-02 -4.945608e-02
## ASV2863      0.0496203018  0.0509193955  5.223790e-02  5.357579e-02
## ASV2910      0.0186212614  0.0191196875  1.962651e-02  2.014182e-02
## ASV2980      0.0238183592  0.0245325507  2.526079e-02  2.600313e-02
## ASV3307      0.0367306936  0.0376044058  3.848339e-02  3.936724e-02
## ASV3474      0.0401335479  0.0416757028  4.326341e-02  4.489716e-02
## ASV3502      0.0339365776  0.0351080523  3.631346e-02  3.755362e-02
## ASV4236      0.0320866455  0.0327271607  3.336824e-02  3.400968e-02
## ASV4842     -0.0037326571 -0.0037518178 -3.764321e-03 -3.769820e-03
## ASV4894     -0.0174974022 -0.0179141636 -1.833357e-02 -1.875546e-02
## ASV5290      0.0192022877  0.0198614434  2.053863e-02  2.123426e-02
## ASV5501      0.0133522302  0.0139272433  1.452688e-02  1.515206e-02
## ASV5795      0.0132852020  0.0137400631  1.420562e-02  1.468184e-02
## ASV5987     -0.0488793881 -0.0500455335 -5.121951e-02 -5.240091e-02
## ASV6267     -0.0550858232 -0.0564010121 -5.772524e-02 -5.905810e-02
## ASV6862      0.0212284381  0.0217670399  2.231396e-02  2.286925e-02
## ASV7145      0.0101210118  0.0104462230  1.078153e-02  1.112717e-02
## ASV7673     -0.0175068505 -0.0179254339 -1.834700e-02 -1.877144e-02
## ASV7789      0.0197622667  0.0206824358  2.163912e-02  2.263325e-02
## ASV7809      0.0039546830  0.0041566322  4.365343e-03  4.580802e-03
## ASV8002     -0.0221189949 -0.0226491693 -2.318336e-02 -2.372143e-02
## ASV8205      0.0131092709  0.0135749092  1.405305e-02  1.454376e-02
## ASV9155     -0.0045076394 -0.0045736027 -4.637513e-03 -4.699277e-03
## ASV9221      0.0094293922  0.0099403819  1.047431e-02  1.103188e-02
## ASV9311     -0.0355070787 -0.0363614356 -3.722275e-02 -3.809084e-02
## ASV9557     -0.0242730297 -0.0248577758 -2.544737e-02 -2.604170e-02
## ASV9936     -0.0489637387 -0.0501447235 -5.133568e-02 -5.253638e-02
## ASV1445      0.0409002731  0.0422895974  4.371265e-02  4.516953e-02
## ASV4232      0.0229301692  0.0240313478  2.518320e-02  2.638770e-02
## ASV6479      0.0143631445  0.0151327692  1.593712e-02  1.677722e-02
## ASV0142     -0.0211754353 -0.0217198804 -2.227194e-02 -2.283162e-02
## ASV0378      0.0164153567  0.0170263358  1.765185e-02  1.829171e-02
## ASV1122      0.0418217836  0.0433289684  4.487903e-02  4.647259e-02
## ASV0123     -0.0183881973 -0.0188469852 -1.931115e-02 -1.978062e-02
## ASV2064      0.0051021500  0.0050417801  4.967908e-03  4.879899e-03
## ASV4459     -0.0007702591 -0.0008128344 -8.603730e-04 -9.132920e-04
## ASV0448      0.0135182492  0.0140532680  1.460440e-02  1.517178e-02
## ASV0397      0.0208272035  0.0214697780  2.212563e-02  2.279482e-02
## ASV0485      0.0228146030  0.0234967426  2.419268e-02  2.490249e-02
## ASV1566      0.0352608165  0.0363413517  3.744362e-02  3.856762e-02
## ASV1365      0.0311399089  0.0320705617  3.301599e-02  3.397595e-02
## ASV1065      0.0457703544  0.0472561891  4.877543e-02  5.032818e-02
## ASV0722     -0.0037922059 -0.0039833591 -4.183859e-03 -4.394082e-03
## ASV12660    -0.0194156882 -0.0198828624 -2.035468e-02 -2.083105e-02
## ASV0223      0.0067771350  0.0070060527  7.241740e-03  7.484364e-03
## ASV0229      0.0125417485  0.0130225363  1.351971e-02  1.403374e-02
## ASV0877     -0.0009603409 -0.0012412951 -1.547033e-03 -1.878917e-03
## ASV0983      0.0210271002  0.0215847399  2.214896e-02  2.271954e-02
## ASV0626      0.0076056947  0.0079581156  8.321923e-03  8.697231e-03
## ASV4146     -0.0018004108 -0.0020458014 -2.312104e-03 -2.600422e-03
## ASV4175     -0.0335594645 -0.0346952678 -3.585749e-02 -3.704611e-02
## ASV2082     -0.0301187107 -0.0316352479 -3.321566e-02 -3.486153e-02
## ASV2272      0.0166506511  0.0172710348  1.791097e-02  1.857088e-02
## ASV2245     -0.0246311229 -0.0254769928 -2.634278e-02 -2.722846e-02
## ASV0590     -0.0310219084 -0.0326008933 -3.424722e-02 -3.596271e-02
## ASV0217      0.0091421281  0.0096465802  1.017188e-02  1.071855e-02
## ASV0416      0.0066582222  0.0065890586  6.505280e-03  6.406364e-03
## ASV1056      0.0256809501  0.0266029971  2.754805e-02  2.851610e-02
## ASV7777     -0.0338682749 -0.0351660382 -3.651195e-02 -3.790799e-02
## ASV0455      0.0050763674  0.0052143721  5.353044e-03  5.492172e-03
## ASV0604      0.0181942332  0.0188917941  1.960999e-02  2.034907e-02
## ASV6100     -0.0254593318 -0.0264892112 -2.755835e-02 -2.866816e-02
## ASV11359    -0.0459855966 -0.0474420305 -4.892529e-02 -5.043485e-02
## ASV6604      0.0076969147  0.0079701178  8.248572e-03  8.532004e-03
## ASV5004     -0.0168614028 -0.0174671704 -1.809205e-02 -1.873651e-02
## ASV1483     -0.0065038267 -0.0066965861 -6.892111e-03 -7.090236e-03
## ASV9773     -0.0230222024 -0.0238869375 -2.478003e-02 -2.570224e-02
## ASV4059      0.0063542539  0.0067086128  7.074232e-03  7.450807e-03
## ASV1193      0.0238801335  0.0246479060  2.543327e-02  2.623631e-02
## ASV4610      0.0025833288  0.0027635966  2.947027e-03  3.133192e-03
## ASV0742      0.0037990616  0.0040416037  4.291567e-03  4.548784e-03
## ASV1502     -0.0053676097 -0.0056332429 -5.906990e-03 -6.188750e-03
## ASV0195     -0.0019114229 -0.0020348999 -2.163699e-03 -2.297938e-03
## ASV1213      0.0102782699  0.0104327080  1.058315e-02  1.072932e-02
## ASV1648     -0.0230986287 -0.0240520133 -2.504289e-02 -2.607255e-02
## ASV6984     -0.0220483133 -0.0229738426 -2.393648e-02 -2.493752e-02
## ASV0396      0.0006120113  0.0006053528  5.916024e-04  5.698881e-04
## ASV4297      0.0171854020  0.0175595266  1.793676e-02  1.831724e-02
## ASV2622      0.0321354636  0.0330229721  3.392549e-02  3.484305e-02
## ASV3512      0.0274952745  0.0288443425  3.025337e-02  3.172446e-02
## ASV2411      0.0333521542  0.0346206501  3.592455e-02  3.726389e-02
## ASV2291     -0.0267566788 -0.0280583865 -2.940942e-02 -3.081069e-02
## ASV0807      0.0339512688  0.0349680222  3.600361e-02  3.705809e-02
## ASV1292      0.0043490138  0.0044113650  4.475284e-03  4.541163e-03
## ASV1035      0.0270813144  0.0278628026  2.866189e-02  2.947898e-02
## ASV0070      0.0037822241  0.0040127213  4.254035e-03  4.506452e-03
## ASV0255      0.0002712290  0.0001542659  2.542804e-05 -1.159782e-04
## ASV0057     -0.0050114413 -0.0050572392 -5.098487e-03 -5.134956e-03
## ASV0077     -0.0001778025 -0.0001553388 -1.331574e-04 -1.115463e-04
## ASV0625      0.0135307706  0.0138301552  1.413093e-02  1.443300e-02
## ASV2464      0.0944480296  0.0967136174  9.900176e-02  1.013119e-01
## ASV1315      0.0446389215  0.0463725930  4.815747e-02  4.999395e-02
## ASV2673      0.0388971005  0.0404439647  4.204040e-02  4.368721e-02
## ASV2161      0.0168797961  0.0175891575  1.832467e-02  1.908700e-02
## ASV0337     -0.0079862657 -0.0082767117 -8.575865e-03 -8.883898e-03
## ASV7680     -0.0536215533 -0.0555737149 -5.758031e-02 -5.964178e-02
## ASV0611      0.0309352495  0.0321241431  3.335226e-02  3.462055e-02
## ASV3118     -0.0363289834 -0.0377711437 -3.925836e-02 -4.079122e-02
## ASV1284     -0.0136783181 -0.0149144094 -1.622710e-02 -1.761967e-02
## ASV0889      0.0181631313  0.0187692526  1.939473e-02  2.004034e-02
## ASV4649     -0.0105227734 -0.0108949461 -1.127788e-02 -1.167176e-02
## ASV1108     -0.0302018724 -0.0314907770 -3.282473e-02 -3.420455e-02
## ASV0738      0.0224074090  0.0235227708  2.468778e-02  2.590419e-02
## ASV0473     -0.0044229870 -0.0045577771 -4.689301e-03 -4.816671e-03
## ASV0598     -0.0137637503 -0.0144907582 -1.525074e-02 -1.604467e-02
## ASV0429      0.0101721595  0.0103626140  1.055049e-02  1.073555e-02
## ASV1549      0.0360942077  0.0375112991  3.897012e-02  4.047082e-02
## ASV1203      0.0186760054  0.0191930120  1.971683e-02  2.024723e-02
## ASV4532      0.0004279813  0.0004690334  5.153970e-04  5.675638e-04
## ASV0274      0.0050293241  0.0051846369  5.339730e-03  5.494139e-03
## ASV0163     -0.0124485123 -0.0127908077 -1.314160e-02 -1.350127e-02
## ASV1298      0.0020835334  0.0022422324  2.414691e-03  2.601843e-03
## ASV9424     -0.0449147392 -0.0467208454 -4.859191e-02 -5.052975e-02
## ASV0412      0.0316514817  0.0325387691  3.344091e-02  3.435792e-02
## ASV0284      0.0012464363  0.0010702767  8.767175e-04  6.648141e-04
## ASV0620     -0.0145164025 -0.0151903586 -1.589003e-02 -1.661601e-02
## ASV0153     -0.0471437784 -0.0489502228 -5.080770e-02 -5.271643e-02
## ASV0498      0.0130744835  0.0134427723  1.381259e-02  1.418336e-02
## ASV0097      0.0094871033  0.0098594074  1.024261e-02  1.063673e-02
## ASV0104     -0.0459067754 -0.0472217095 -4.855588e-02 -4.990883e-02
## ASV1282      0.0101436040  0.0101891812  1.021709e-02  1.022611e-02
## ASV3883     -0.0209535618 -0.0217839058 -2.263587e-02 -2.350915e-02
## ASV0801      0.0083831087  0.0087378781  9.108259e-03  9.494960e-03
## ASV1611     -0.0412839147 -0.0429054780 -4.457863e-02 -4.630418e-02
## ASV0227     -0.0125564316 -0.0131607999 -1.378924e-02 -1.444240e-02
## ASV0833      0.0118131260  0.0122129562  1.262256e-02  1.304201e-02
## ASV0718      0.0532708060  0.0551159925  5.700839e-02  5.894833e-02
## ASV1139     -0.0023621316 -0.0027022557 -3.063090e-03 -3.445194e-03
## ASV0766     -0.0105278329 -0.0109497668 -1.138334e-02 -1.182851e-02
## ASV2091      0.0276829313  0.0282385263  2.879142e-02  2.934114e-02
## ASV1238     -0.0488195798 -0.0509603164 -5.319175e-02 -5.551727e-02
## ASV9193     -0.0130053105 -0.0137598257 -1.455126e-02 -1.538080e-02
## ASV0290      0.0020818692  0.0021306588  2.184253e-03  2.243147e-03
## ASV0231      0.0117364898  0.0120076847  1.227761e-02  1.254577e-02
## ASV0185      0.0168275324  0.0176511087  1.850974e-02  1.940451e-02
## ASV2330      0.0107125458  0.0109355765  1.116122e-02  1.138967e-02
## ASV3119     -0.0145058676 -0.0151962760 -1.591487e-02 -1.666242e-02
## ASV2368     -0.0280388341 -0.0293201448 -3.065570e-02 -3.204729e-02
## ASV0122     -0.0082446314 -0.0084925344 -8.745620e-03 -9.003964e-03
## ASV1044      0.0300969596  0.0313120106  3.256960e-02  3.387083e-02
## ASV0160     -0.0067142707 -0.0068859709 -7.062528e-03 -7.244286e-03
## ASV0326      0.0023465715  0.0023959531  2.443726e-03  2.489649e-03
## ASV1388      0.0427087286  0.0439424207  4.519603e-02  4.646935e-02
## ASV0792      0.0269582833  0.0276051661  2.825660e-02  2.891233e-02
## ASV0036     -0.0137311702 -0.0142276084 -1.473518e-02 -1.525367e-02
## ASV2125      0.0318031119  0.0327427859  3.369698e-02  3.466530e-02
## ASV1075     -0.0011269536 -0.0012033055 -1.284723e-03 -1.371458e-03
## ASV0390      0.0256102507  0.0267312359  2.789673e-02  2.910810e-02
## ASV3790     -0.0294795448 -0.0305691108 -3.169125e-02 -3.284651e-02
## ASV1535     -0.0128756942 -0.0134408880 -1.402468e-02 -1.462720e-02
## ASV0263      0.0325932281  0.0336877109  3.480867e-02  3.595624e-02
## ASV0675      0.0569546234  0.0591089273  6.132801e-02  6.361279e-02
## ASV3348      0.0056725036  0.0058978264  6.129122e-03  6.366316e-03
## ASV0058     -0.0122844244 -0.0126238405 -1.296760e-02 -1.331557e-02
## ASV4142      0.0146511157  0.0150102411  1.537445e-02  1.574389e-02
## ASV0059     -0.0093774021 -0.0096208660 -9.866784e-03 -1.011507e-02
## ASV0013     -0.0202414279 -0.0209038160 -2.158171e-02 -2.227523e-02
## ASV0033     -0.0118869482 -0.0123226965 -1.276912e-02 -1.322614e-02
## ASV4354     -0.0133475871 -0.0138492114 -1.436593e-02 -1.489789e-02
## ASV0022     -0.0101456115 -0.0105253215 -1.091498e-02 -1.131453e-02
## ASV0134     -0.0123877886 -0.0129716247 -1.358169e-02 -1.421907e-02
## ASV0415      0.0023301026  0.0024191394  2.510117e-03  2.603020e-03
## ASV10103    -0.0542130885 -0.0562641495 -5.837544e-02 -6.054755e-02
## ASV1613      0.0243813168  0.0248698973  2.535213e-02  2.582714e-02
## ASV0135     -0.0022752033 -0.0022923473 -2.307194e-03 -2.319631e-03
## ASV0469     -0.0393698944 -0.0406179076 -4.189746e-02 -4.320919e-02
## ASV0471      0.0267060621  0.0276341666  2.859072e-02  2.957664e-02
## ASV0451     -0.0099725376 -0.0104451502 -1.093431e-02 -1.144017e-02
## ASV0747      0.0155597434  0.0160574885  1.656412e-02  1.707941e-02
## ASV1314     -0.0216274565 -0.0225772810 -2.356430e-02 -2.458958e-02
## ASV0425     -0.0400143904 -0.0409957437 -4.198822e-02 -4.299174e-02
## ASV0559     -0.0150784118 -0.0157068981 -1.636132e-02 -1.704258e-02
## ASV0148      0.0016837910  0.0018979144  2.126500e-03  2.370175e-03
## ASV0129      0.0120618618  0.0127551028  1.348126e-02  1.424133e-02
## ASV1072      0.0003766061  0.0002848358  1.855981e-04  7.867513e-05
## ASV2390      0.0149105664  0.0150142723  1.510154e-02  1.517165e-02
## ASV0548      0.0171624803  0.0176858649  1.821915e-02  1.876233e-02
## ASV0168     -0.0080664413 -0.0083030953 -8.544519e-03 -8.790765e-03
## ASV0066     -0.0088294874 -0.0090474022 -9.265238e-03 -9.482640e-03
## ASV0468     -0.0062163644 -0.0064560879 -6.704514e-03 -6.961944e-03
## ASV0172     -0.0003952964 -0.0003191492 -2.362540e-04 -1.463236e-04
## ASV0236      0.0094575974  0.0100557113  1.068110e-02  1.133433e-02
## ASV0250      0.0255241362  0.0267396161  2.800681e-02  2.932736e-02
## ASV0338      0.0077272323  0.0079554343  8.184974e-03  8.415482e-03
## ASV0450     -0.0037478674 -0.0039512680 -4.163874e-03 -4.385925e-03
## ASV0377      0.0110148354  0.0112883472  1.156179e-02  1.183470e-02
## ASV1022      0.0007459258  0.0008420248  9.463343e-04  1.059365e-03
## ASV6174     -0.0015846003 -0.0016521678 -1.718466e-03 -1.782866e-03
## ASV0786     -0.0050136634 -0.0052312766 -5.453487e-03 -5.679996e-03
## ASV0053     -0.0145486092 -0.0150281444 -1.551859e-02 -1.601999e-02
## ASV0697     -0.0071974438 -0.0074190360 -7.647500e-03 -7.883227e-03
## ASV0785      0.0160221986  0.0164942102  1.697613e-02  1.746820e-02
## ASV1967     -0.0159282999 -0.0164061219 -1.689308e-02 -1.738909e-02
## ASV0385      0.0073739222  0.0076093997  7.846710e-03  8.085411e-03
## ASV0295      0.0045865731  0.0048534405  5.133184e-03  5.426221e-03
## ASV0072     -0.0103695845 -0.0105746450 -1.077637e-02 -1.097431e-02
## ASV0157      0.0037931557  0.0041169451  4.460574e-03  4.824862e-03
## ASV0501      0.0313998805  0.0323865365  3.338956e-02  3.440846e-02
## ASV10729    -0.0433305089 -0.0448961861 -4.650553e-02 -4.815906e-02
## ASV1470      0.0103791218  0.0104272422  1.045990e-02  1.047611e-02
## ASV0050     -0.0292398774 -0.0300574763 -3.088594e-02 -3.172493e-02
## ASV0411     -0.0098149149 -0.0102293621 -1.066050e-02 -1.110899e-02
## ASV0549      0.0140163773  0.0145250461  1.504724e-02  1.558300e-02
## ASV0184      0.0043875941  0.0045683589  4.757168e-03  4.954424e-03
## ASV0705      0.0056379660  0.0057296013  5.816859e-03  5.899258e-03
## ASV1715      0.0171920723  0.0177564030  1.833345e-02  1.892323e-02
## ASV0603      0.0043929153  0.0046302884  4.880631e-03  5.144538e-03
## ASV0826      0.0271867352  0.0280589156  2.895216e-02  2.986678e-02
## ASV0034     -0.0071663429 -0.0073385396 -7.511503e-03 -7.685117e-03
## ASV0838     -0.0081585942 -0.0090093547 -9.920820e-03 -1.089609e-02
## ASV0614     -0.0073563863 -0.0075882011 -7.825354e-03 -8.067931e-03
## ASV0014     -0.0197331769 -0.0203418889 -2.096225e-02 -2.159418e-02
## ASV0585     -0.0053783779 -0.0057376750 -6.110274e-03 -6.496014e-03
## ASV0016     -0.0206620549 -0.0213017227 -2.195385e-02 -2.261837e-02
## ASV5394     -0.0168184396 -0.0173557337 -1.790135e-02 -1.845472e-02
## ASV0666      0.0269159498  0.0275717353  2.823340e-02  2.890080e-02
## ASV2085     -0.0051644250 -0.0057247446 -6.318775e-03 -6.947783e-03
## ASV0003     -0.0140595732 -0.0144959575 -1.494109e-02 -1.539495e-02
## ASV0346      0.0090075890  0.0093167698  9.631638e-03  9.951997e-03
## ASV0267      0.0019838775  0.0020612192  2.136396e-03  2.208733e-03
## ASV0353      0.0144932312  0.0150473671  1.561807e-02  1.620553e-02
## ASV2419      0.0283713016  0.0291730658  2.998370e-02  3.080241e-02
## ASV0447      0.0212572911  0.0220695952  2.290719e-02  2.377062e-02
## ASV0654      0.0243467493  0.0250826746  2.583139e-02  2.659275e-02
## ASV0151      0.0068546961  0.0071798798  7.516923e-03  7.865959e-03
## ASV0065     -0.0088790858 -0.0091389571 -9.403488e-03 -9.672687e-03
## ASV0527      0.0229636453  0.0236636477  2.437613e-02  2.510086e-02
## ASV4055     -0.0079457616 -0.0084102194 -8.902520e-03 -9.424245e-03
## ASV0166     -0.0092860389 -0.0095125443 -9.741659e-03 -9.973458e-03
## ASV0417     -0.0021966633 -0.0021916315 -2.183453e-03 -2.172117e-03
## ASV0078     -0.0052363363 -0.0053259709 -5.412009e-03 -5.494056e-03
## ASV0322      0.0033783006  0.0036826506  4.006223e-03  4.349743e-03
## ASV0156     -0.0200842513 -0.0208584105 -2.165895e-02 -2.248665e-02
## ASV0648     -0.0435296471 -0.0451267085 -4.676707e-02 -4.845083e-02
## ASV0407     -0.0042143092 -0.0044085922 -4.611173e-03 -4.822333e-03
## ASV2030     -0.0080606826 -0.0084560896 -8.870808e-03 -9.305522e-03
## ASV0300      0.0057786269  0.0059963345  6.219640e-03  6.448507e-03
## ASV1150      0.0017828408  0.0018485556  1.914798e-03  1.981389e-03
## ASV0958      0.0199255679  0.0207992128  2.170671e-02  2.264899e-02
## ASV0216     -0.0154304310 -0.0160211277 -1.663518e-02 -1.727356e-02
## ASV0446      0.0260295971  0.0269421346  2.787676e-02  2.883344e-02
## ASV0367     -0.0162115487 -0.0167741889 -1.735113e-02 -1.794244e-02
## ASV0200     -0.0091399652 -0.0094244153 -9.712931e-03 -1.000523e-02
## ASV0334     -0.0016543946 -0.0016692745 -1.686365e-03 -1.706088e-03
## ASV1311      0.0017341265  0.0016560981  1.568758e-03  1.471672e-03
## ASV0458      0.0027853100  0.0027177633  2.641467e-03  2.556129e-03
## ASV1371      0.0018008324  0.0018476167  1.893331e-03  1.937768e-03
## ASV0418      0.0149820351  0.0153433807  1.570779e-02  1.607518e-02
## ASV0004      0.0020104697  0.0020530388  2.095609e-03  2.138150e-03
## ASV1943      0.0213832482  0.0213873217  2.136989e-02  2.133075e-02
## ASV1495     -0.0126118767 -0.0133070186 -1.403367e-02 -1.479267e-02
## ASV0901     -0.0218108220 -0.0227210308 -2.366603e-02 -2.464692e-02
## ASV0628      0.0042419677  0.0042223863  4.193007e-03  4.153228e-03
## ASV0400      0.0034826632  0.0035037947  3.518032e-03  3.524754e-03
## ASV0116     -0.0061704380 -0.0064153780 -6.668674e-03 -6.930526e-03
## ASV0788      0.0560468049  0.0583445302  6.072756e-02  6.319865e-02
## ASV0117      0.0047014432  0.0048974705  5.100145e-03  5.309608e-03
## ASV3137     -0.0006769547 -0.0006785121 -6.779585e-04 -6.750504e-04
## ASV0001      0.0020367310  0.0020768242  2.117048e-03  2.157433e-03
## ASV1651      0.0065480204  0.0067115859  6.878102e-03  7.047753e-03
## ASV1692      0.0450809523  0.0468559178  4.869183e-02  5.059045e-02
## ASV0660      0.0045268190  0.0043885856  4.231492e-03  4.054773e-03
## ASV0508      0.0001432943  0.0001261646  1.066609e-04  8.457127e-05
## ASV1660     -0.0112655767 -0.0117111044 -1.216777e-02 -1.263536e-02
## ASV0233      0.0120173844  0.0124351604  1.286429e-02  1.330496e-02
## ASV1343     -0.0254955384 -0.0265056713 -2.755098e-02 -2.863243e-02
## ASV0209      0.0067017011  0.0068074797  6.909383e-03  7.007035e-03
## ASV0193     -0.0080501888 -0.0081725194 -8.289298e-03 -8.400037e-03
## ASV0357      0.0104480936  0.0110132082  1.160599e-02  1.222747e-02
## ASV0198      0.0085703523  0.0088525193  9.142776e-03  9.441344e-03
## ASV0007      0.0015118177  0.0015305905  1.548841e-03  1.566592e-03
## ASV1772      0.0018208369  0.0022025573  2.621856e-03  3.081495e-03
## ASV0009      0.0010130307  0.0010161829  1.018608e-03  1.020348e-03
## ASV0006     -0.0034857914 -0.0036275901 -3.773827e-03 -3.924546e-03
## ASV0011     -0.0099107964 -0.0102769579 -1.065396e-02 -1.104199e-02
## ASV0015      0.0006551109  0.0006456872  6.345008e-04  6.214720e-04
## ASV0017      0.0008481437  0.0008468761  8.442714e-04  8.402722e-04
## ASV0235     -0.0095062460 -0.0098738938 -1.025408e-02 -1.064718e-02
## ASV0382      0.0055960130  0.0056889963  5.774486e-03  5.851590e-03
## ASV2357      0.0302561113  0.0314011065  3.258133e-02  3.379726e-02
## ASV0567     -0.0071512816 -0.0074896794 -7.843932e-03 -8.214685e-03
## ASV0165      0.0047035048  0.0048625359  5.025220e-03  5.191568e-03
## ASV0005      0.0058282113  0.0059969681  6.168022e-03  6.341282e-03
## ASV0384      0.0022209982  0.0024029776  2.596469e-03  2.802017e-03
## ASV0002      0.0009787407  0.0010080287  1.037958e-03  1.068529e-03
## ASV3017      0.0235253058  0.0240114800  2.449550e-02  2.497692e-02
## ASV0091     -0.0011356746 -0.0012004361 -1.269564e-03 -1.343346e-03
## ASV0186     -0.0120104901 -0.0123530600 -1.269902e-02 -1.304807e-02
## ASV0370      0.0059040201  0.0060840829  6.268976e-03  6.458907e-03
## ASV0018      0.0077267372  0.0079616138  8.200573e-03  8.443553e-03
## ASV1377      0.0625403689  0.0640649854  6.560132e-02  6.714885e-02
## ASV0019      0.0082189394  0.0084738767  8.733657e-03  8.998247e-03
## ASV0023     -0.0061470378 -0.0063642774 -6.586546e-03 -6.813792e-03
## ASV2194      0.0117538207  0.0122601861  1.278584e-02  1.333129e-02
## ASV1155      0.0290529231  0.0299696747  3.091212e-02  3.188115e-02
## ASV0510     -0.0050303483 -0.0051329923 -5.238455e-03 -5.346950e-03
## ASV2371     -0.0164721554 -0.0169103412 -1.735333e-02 -1.780086e-02
## ASV0024     -0.0075646267 -0.0078319160 -8.105584e-03 -8.385598e-03
## ASV2452      0.0107097681  0.0107821572  1.084386e-02  1.089447e-02
## ASV2332     -0.0525028343 -0.0541542089 -5.584504e-02 -5.757583e-02
## ASV2591      0.0226832355  0.0235024986  2.433784e-02  2.518884e-02
## ASV0521      0.0158802630  0.0164836708  1.710596e-02  1.774751e-02
## ASV5542      0.0143046213  0.0148108308  1.533110e-02  1.586567e-02
## ASV0336     -0.0043678223 -0.0045973357 -4.837781e-03 -5.089666e-03
## ASV10102     0.0263821790  0.0272876755  2.821393e-02  2.916089e-02
## ASV16823    -0.0254816326 -0.0260859522 -2.669668e-02 -2.731375e-02
## ASV3104      0.1318393282  0.1349653167  1.381244e-01  1.413162e-01
## ASV0781      0.0264685437  0.0273810997  2.832059e-02  2.928769e-02
## ASV10899     0.0288109181  0.0301678286  3.157914e-02  3.304634e-02
## ASV11222    -0.0448451468 -0.0459081804 -4.698244e-02 -4.806784e-02
## ASV11327    -0.0402607622 -0.0412149519 -4.217921e-02 -4.315346e-02
## ASV12458    -0.0448402611 -0.0459028135 -4.697657e-02 -4.806144e-02
## ASV1636      0.0302855443  0.0311338411  3.199710e-02  3.287541e-02
## ASV1890     -0.0161359284 -0.0164418069 -1.675243e-02 -1.706837e-02
## ASV2898      0.0409717850  0.0421344067  4.331918e-02  4.452644e-02
## ASV8328      0.0263210133  0.0277864096  2.931592e-02  3.091102e-02
## ASV0709     -0.0488496183 -0.0502703539 -5.171499e-02 -5.318331e-02
## ASV0856      0.0567155164  0.0588666334  6.107854e-02  6.335164e-02
## ASV0909      0.0295166235  0.0309514738  3.244178e-02  3.398871e-02
## ASV0937     -0.0400610068 -0.0417304621 -4.346321e-02 -4.526104e-02
## ASV11390    -0.0639882654 -0.0655039230 -6.703554e-02 -6.858300e-02
## ASV11966     0.0299900389  0.0311404736  3.232197e-02  3.353455e-02
## ASV12990     0.0123537762  0.0126784609  1.300878e-02  1.334480e-02
## ASV14797     0.0175777297  0.0180246373  1.847872e-02  1.894010e-02
## ASV14904    -0.0918153683 -0.0939897081 -9.618694e-02 -9.840688e-02
## ASV15304     0.0218434364  0.0227288236  2.363937e-02  2.457511e-02
## ASV16696    -0.0317227226 -0.0324739227 -3.323304e-02 -3.400000e-02
## ASV1690      0.0905074775  0.0935914731  9.673669e-02  9.994195e-02
## ASV2029      0.0492190009  0.0507535995  5.232231e-02  5.392540e-02
## ASV2834      0.0713574424  0.0737365658  7.616708e-02  7.864872e-02
## ASV4003      0.0866369727  0.0907138736  9.497199e-02  9.941838e-02
## ASV4064      0.0356038274  0.0368739114  3.817966e-02  3.952176e-02
## ASV4294      0.0336677991  0.0352371657  3.686949e-02  3.856650e-02
## ASV4609      0.0171680000  0.0177600404  1.837035e-02  1.899932e-02
## ASV6283     -0.0296522884 -0.0303543898 -3.106389e-02 -3.178074e-02
## ASV6491     -0.0425000959 -0.0435064079 -4.452334e-02 -4.555081e-02
## ASV7453      0.0412175635  0.0428373153  4.450296e-02  4.621468e-02
## ASV7959      0.0229359226  0.0240655510  2.524296e-02  2.646966e-02
## ASV8219      0.3672859969  0.3759829803  3.847719e-01  3.936522e-01
## ASV8547     -0.0380495942 -0.0389506175 -3.986118e-02 -4.078122e-02
## ASV9319      0.0306346595  0.0318950778  3.320182e-02  3.455623e-02
## ASV9382     -0.0744489231 -0.0762120119 -7.799380e-02 -7.979416e-02
## ASV11516    -0.0497259883 -0.0509036892 -5.209390e-02 -5.329654e-02
## ASV14377    -0.0359050318 -0.0367554793 -3.761498e-02 -3.848346e-02
## ASV1867      0.0460036982  0.0477306450  4.951250e-02  5.135064e-02
## ASV1895      0.0091048054  0.0090565596  8.989700e-03  8.903459e-03
## ASV3168      0.0167636320  0.0170799070  1.739367e-02  1.770462e-02
## ASV4449      0.1427918262  0.1478669875  1.530959e-01  1.584824e-01
## ASV6596      0.0468203703  0.0489580289  5.117932e-02  5.348627e-02
## ASV7492      0.0082737267  0.0088904431  9.535910e-03  1.021062e-02
## ASV9854     -0.0072148540 -0.0073729128 -7.531803e-03 -7.691491e-03
## ASV6296      0.6025265274  0.6168021883  6.312305e-01  6.458106e-01
## ASV4201      0.0208475242  0.0220692963  2.335132e-02  2.469583e-02
## ASV0552      0.0299933490  0.0310104080  3.204934e-02  3.310983e-02
## ASV3671     -0.0207229745 -0.0216196036 -2.255682e-02 -2.353633e-02
## ASV3529      0.0037026211  0.0039607844  4.225843e-03  4.497477e-03
## ASV1060      0.0109852719  0.0115040391  1.204640e-02  1.261329e-02
## ASV0239     -0.0056725839 -0.0057513857 -5.827131e-03 -5.899566e-03
## ASV5711     -0.0403647319 -0.0416103207 -4.288201e-02 -4.417976e-02
## ASV4152     -0.0658575207 -0.0680502084 -7.029029e-02 -7.257733e-02
## ASV1461      0.0192633771  0.0195782875  1.988812e-02  2.019253e-02
## ASV2877      0.0103062117  0.0104520237  1.059081e-02  1.072197e-02
## ASV0012      0.0029551855  0.0030571979  3.161921e-03  3.269383e-03
## ASV9823     -0.0026974377 -0.0030286213 -3.381743e-03 -3.757621e-03
## ASV0008      0.0030639586  0.0031684931  3.275810e-03  3.385943e-03
## ASV7832     -0.0421197852 -0.0436670684 -4.525856e-02 -4.689480e-02
## ASV1915     -0.0052733710 -0.0055063010 -5.749484e-03 -6.003276e-03
## ASV0055     -0.0058385987 -0.0061123872 -6.397299e-03 -6.693667e-03
## ASV0032      0.0003522280  0.0003446717  3.374532e-04  3.307627e-04
## ASV2977     -0.0528839908 -0.0545786815 -5.630590e-02 -5.806512e-02
## ASV0466      0.0251261317  0.0254793467  2.581944e-02  2.614561e-02
## ASV3866      0.0359939655  0.0374511992  3.896113e-02  4.052526e-02
## ASV0040      0.0113077559  0.0117039967  1.211049e-02  1.252730e-02
## ASV0496     -0.0098826489 -0.0104025318 -1.094205e-02 -1.150137e-02
## ASV0052      0.0096510984  0.0100024738  1.036469e-02  1.073803e-02
## ASV3828     -0.0208848453 -0.0213599692 -2.183890e-02 -2.232154e-02
## ASV1930      0.0110744725  0.0112952069  1.151458e-02  1.173239e-02
## ASV2126      0.0249811112  0.0257890870  2.661785e-02  2.746778e-02
## ASV0793      0.0381617347  0.0395889266  4.106046e-02  4.257743e-02
## ASV0299     -0.0028906371 -0.0031198150 -3.365401e-03 -3.628279e-03
## ASV0208      0.0263968218  0.0273887776  2.841340e-02  2.947157e-02
## ASV0511     -0.0055314394 -0.0056393295 -5.749648e-03 -5.862660e-03
## ASV1123     -0.0180529902 -0.0183359998 -1.860875e-02 -1.887009e-02
## ASV0099      0.0024249284  0.0025658229  2.713812e-03  2.869130e-03
## ASV0752     -0.0225364249 -0.0234649247 -2.442647e-02 -2.542191e-02
## ASV0883      0.0289338438  0.0300088601  3.111135e-02  3.224119e-02
## ASV0683      0.0370355674  0.0384599243  3.992807e-02  4.144067e-02
## ASV4117     -0.0544543886 -0.0565111483 -5.863342e-02 -6.082260e-02
## ASV2172     -0.0007091711 -0.0008681258 -1.039364e-03 -1.223487e-03
## ASV0330     -0.0106153001 -0.0110328061 -1.146519e-02 -1.191291e-02
## ASV0728      0.0433611686  0.0447643550  4.620159e-02  4.767345e-02
## ASV0499      0.0150101801  0.0156076737  1.622473e-02  1.686172e-02
## ASV0120     -0.0189329753 -0.0194988724 -2.007276e-02 -2.065422e-02
## ASV1446      0.0019160389  0.0015636154  1.179005e-03  7.606881e-04
## ASV17171    -0.0409134657 -0.0424374555 -4.401089e-02 -4.563488e-02
## ASV0533      0.0044072545  0.0045952572  4.789430e-03  4.989836e-03
## ASV2495     -0.0183323432 -0.0192016697 -2.010279e-02 -2.103608e-02
## ASV5582      0.0063830613  0.0062737178  6.144464e-03  5.994094e-03
## ASV1488      0.0039809736  0.0039939330  3.998983e-03  3.995555e-03
## ASV0682      0.0110098437  0.0114364625  1.187545e-02  1.232688e-02
## ASV0068     -0.0146406221 -0.0150746173 -1.551360e-02 -1.595716e-02
## ASV1987     -0.0499366417 -0.0519488502 -5.402610e-02 -5.616944e-02
## ASV0035     -0.0095512255 -0.0101347672 -1.075011e-02 -1.139857e-02
## ASV7192     -0.0197569285 -0.0202882814 -2.082409e-02 -2.136387e-02
## ASV0873     -0.0692474564 -0.0729368942 -7.675529e-02 -8.070342e-02
## ASV4749     -0.0163106579 -0.0173034796 -1.834177e-02 -1.942668e-02
## ASV2174      0.0063677786  0.0062959147  6.209054e-03  6.106647e-03
## ASV1476     -0.0224854577 -0.0234289555 -2.440573e-02 -2.541652e-02
## ASV0740     -0.0609971537 -0.0635154772 -6.612562e-02 -6.883016e-02
## ASV0170     -0.0098353080 -0.0101893967 -1.055418e-02 -1.092989e-02
## ASV2466     -0.0462816369 -0.0479931518 -4.975672e-02 -5.157322e-02
## ASV1709      0.0171141310  0.0179275316  1.878652e-02  1.969376e-02
## ASV6170     -0.0784819069 -0.0814816961 -8.457319e-02 -8.775765e-02
## ASV3673      0.0408803873  0.0424887396  4.414709e-02  4.585603e-02
## ASV1745     -0.0129850620 -0.0135522229 -1.413957e-02 -1.474749e-02
##                                                                    
## (Intercept)  2.507137e-01  2.582800e-01  2.659779e-01  2.738053e-01
## ASV1236      3.975918e-02  4.080337e-02  4.186292e-02  4.293777e-02
## ASV0421      1.270951e-02  1.323257e-02  1.376839e-02  1.431681e-02
## ASV0691     -1.681104e-02 -1.695177e-02 -1.708567e-02 -1.721261e-02
## ASV0899      3.240729e-02  3.315423e-02  3.390797e-02  3.466858e-02
## ASV1004      7.853298e-02  8.051371e-02  8.251890e-02  8.454828e-02
## ASV1041     -2.614083e-02 -2.649070e-02 -2.682429e-02 -2.714070e-02
## ASV1058      4.979690e-02  5.111188e-02  5.244731e-02  5.380315e-02
## ASV12542     1.705954e-02  1.749799e-02  1.794606e-02  1.840403e-02
## ASV1294      4.734021e-02  4.864961e-02  4.998500e-02  5.134685e-02
## ASV13113     2.975364e-02  3.104265e-02  3.237992e-02  3.376664e-02
## ASV1318      4.577439e-02  4.696835e-02  4.818175e-02  4.941483e-02
## ASV2269     -7.311400e-02 -7.469414e-02 -7.627766e-02 -7.786393e-02
## ASV2542      5.947772e-02  6.172266e-02  6.403730e-02  6.642291e-02
## ASV2660     -2.892731e-02 -2.958957e-02 -3.025771e-02 -3.093170e-02
## ASV2737      8.352399e-03  8.548588e-03  8.749041e-03  8.953870e-03
## ASV2840      2.977454e-02  3.017793e-02  3.057120e-02  3.095403e-02
## ASV3053      1.923525e-01  1.969711e-01  2.016527e-01  2.063971e-01
## ASV3077      1.324271e-02  1.360681e-02  1.397879e-02  1.435876e-02
## ASV3134      4.348360e-02  4.529140e-02  4.716381e-02  4.910233e-02
## ASV3140      4.201673e-02  4.330963e-02  4.462703e-02  4.596876e-02
## ASV3579      2.466316e-02  2.568232e-02  2.673126e-02  2.780995e-02
## ASV6119     -2.000585e-02 -2.044102e-02 -2.087759e-02 -2.131535e-02
## ASV7557     -4.066007e-02 -4.154594e-02 -4.243478e-02 -4.332619e-02
## ASV8422      1.044702e-02  1.074165e-02  1.104386e-02  1.135391e-02
## ASV1086     -1.279826e-03 -1.327535e-03 -1.377623e-03 -1.430172e-03
## ASV1310      2.022626e-02  2.069857e-02  2.117357e-02  2.165098e-02
## ASV15750    -1.040257e-03 -1.002496e-03 -9.608136e-04 -9.150740e-04
## ASV16905    -8.366653e-03 -8.549936e-03 -8.733891e-03 -8.918413e-03
## ASV2033      5.934169e-02  6.146090e-02  6.363732e-02  6.587183e-02
## ASV2089      1.768060e-02  1.806638e-02  1.845333e-02  1.884119e-02
## ASV2127      6.171779e-02  6.331228e-02  6.493011e-02  6.657120e-02
## ASV2725      4.334006e-02  4.428041e-02  4.522631e-02  4.617755e-02
## ASV2804     -1.732897e-02 -1.770956e-02 -1.809153e-02 -1.847460e-02
## ASV3075      5.680470e-02  5.891746e-02  6.109984e-02  6.335344e-02
## ASV3327      8.134299e-02  8.415368e-02  8.703711e-02  8.999423e-02
## ASV3342      6.909898e-02  7.153522e-02  7.403986e-02  7.661394e-02
## ASV3532     -7.387436e-02 -7.656979e-02 -7.935561e-02 -8.223448e-02
## ASV3600      3.381264e-02  3.494873e-02  3.611253e-02  3.730422e-02
## ASV4013      5.169170e-02  5.310268e-02  5.453214e-02  5.597953e-02
## ASV4136      4.725287e-02  4.845463e-02  4.967471e-02  5.091308e-02
## ASV4195      1.770177e-01  1.809142e-01  1.848237e-01  1.887433e-01
## ASV4407     -6.840793e-02 -6.991413e-02 -7.142518e-02 -7.293988e-02
## ASV4717      8.977788e-03  9.182509e-03  9.393393e-03  9.610867e-03
## ASV6794      2.727220e-02  2.798218e-02  2.870725e-02  2.944780e-02
## ASV8324     -3.511719e-02 -3.589129e-02 -3.666777e-02 -3.744600e-02
## ASV8981      3.894202e-03  4.156170e-03  4.429917e-03  4.715670e-03
## ASV9859      3.414403e-02  3.585288e-02  3.763867e-02  3.950405e-02
## ASV0936      4.860559e-02  5.011193e-02  5.164553e-02  5.320601e-02
## ASV12683    -3.457944e-04 -3.266229e-04 -3.036447e-04 -2.765476e-04
## ASV1293      2.317792e-02  2.372661e-02  2.428058e-02  2.483972e-02
## ASV13055     2.757079e-03  2.940440e-03  3.132518e-03  3.333603e-03
## ASV17063    -1.823331e-02 -1.863481e-02 -1.903731e-02 -1.944048e-02
## ASV2228      1.487183e-02  1.519932e-02  1.552762e-02  1.585647e-02
## ASV2769      5.938607e-03  6.152475e-03  6.369370e-03  6.589078e-03
## ASV2803      1.327158e-02  1.354124e-02  1.381407e-02  1.409025e-02
## ASV2896      2.359205e-02  2.460652e-02  2.566286e-02  2.676264e-02
## ASV3062      3.164651e-02  3.288714e-02  3.416259e-02  3.547302e-02
## ASV3107      3.796658e-02  3.935046e-02  4.077450e-02  4.223927e-02
## ASV3265      3.233125e-02  3.306938e-02  3.381284e-02  3.456135e-02
## ASV3666     -6.536342e-04 -7.036695e-04 -7.557449e-04 -8.098364e-04
## ASV4497      1.249911e-02  1.283358e-02  1.317345e-02  1.351873e-02
## ASV6914     -4.540155e-03 -4.729190e-03 -4.923514e-03 -5.123110e-03
## ASV0576     -2.926253e-02 -2.971715e-02 -3.016696e-02 -3.061165e-02
## ASV0673      5.088503e-02  5.232711e-02  5.379737e-02  5.529622e-02
## ASV0772      2.654481e-02  2.741527e-02  2.830936e-02  2.922759e-02
## ASV0862      1.193099e-02  1.244507e-02  1.296996e-02  1.350526e-02
## ASV0898      2.596655e-02  2.687107e-02  2.779789e-02  2.874725e-02
## ASV0910      2.891920e-02  2.997037e-02  3.105170e-02  3.216362e-02
## ASV0964     -1.198848e-02 -1.220463e-02 -1.242120e-02 -1.263821e-02
## ASV10059     2.477207e-02  2.575290e-02  2.676381e-02  2.780514e-02
## ASV10263    -2.778537e-02 -2.839822e-02 -2.901273e-02 -2.962855e-02
## ASV1088      5.190274e-02  5.389988e-02  5.596450e-02  5.809823e-02
## ASV1101      3.949940e-02  4.040130e-02  4.131040e-02  4.222654e-02
## ASV1183      1.498815e-02  1.550503e-02  1.603711e-02  1.658481e-02
## ASV11956     8.137581e-03  8.320957e-03  8.508707e-03  8.701024e-03
## ASV12774    -2.827661e-03 -2.996254e-03 -3.171090e-03 -3.352231e-03
## ASV1321      7.680572e-02  7.954703e-02  8.235744e-02  8.523702e-02
## ASV13793    -1.916237e-02 -1.958533e-02 -2.000961e-02 -2.043502e-02
## ASV14482     1.325216e-03  1.389107e-03  1.456494e-03  1.527481e-03
## ASV15483     1.179873e-02  1.219410e-02  1.259932e-02  1.301453e-02
## ASV2062      4.558514e-02  4.696043e-02  4.836514e-02  4.979942e-02
## ASV2132      4.451414e-02  4.598543e-02  4.748927e-02  4.902559e-02
## ASV2413      3.225364e-02  3.317643e-02  3.411936e-02  3.508281e-02
## ASV2490      7.982952e-02  8.153629e-02  8.325411e-02  8.498268e-02
## ASV2594      1.810881e-02  1.884541e-02  1.960996e-02  2.040330e-02
## ASV2822     -5.056982e-02 -5.168817e-02 -5.281067e-02 -5.393694e-02
## ASV2863      5.493308e-02  5.630978e-02  5.770594e-02  5.912160e-02
## ASV2910      2.066576e-02  2.119843e-02  2.173996e-02  2.229050e-02
## ASV2980      2.675963e-02  2.753036e-02  2.831542e-02  2.911488e-02
## ASV3307      4.025561e-02  4.114817e-02  4.204465e-02  4.294481e-02
## ASV3474      4.657739e-02  4.830449e-02  5.007884e-02  5.190073e-02
## ASV3502      3.882938e-02  4.014159e-02  4.149112e-02  4.287884e-02
## ASV4236      3.465129e-02  3.529290e-02  3.593430e-02  3.657532e-02
## ASV4842     -3.767993e-03 -3.758540e-03 -3.741188e-03 -3.715686e-03
## ASV4894     -1.917969e-02 -1.960613e-02 -2.003466e-02 -2.046520e-02
## ASV5290      2.194875e-02  2.268253e-02  2.343606e-02  2.420979e-02
## ASV5501      1.580369e-02  1.648270e-02  1.719001e-02  1.792657e-02
## ASV5795      1.516870e-02  1.566612e-02  1.617403e-02  1.669234e-02
## ASV5987     -5.358940e-02 -5.478468e-02 -5.598648e-02 -5.719457e-02
## ASV6267     -6.039921e-02 -6.174828e-02 -6.310502e-02 -6.446918e-02
## ASV6862      2.343298e-02  2.400522e-02  2.458601e-02  2.517542e-02
## ASV7145      1.148339e-02  1.185041e-02  1.222843e-02  1.261768e-02
## ASV7673     -1.919863e-02 -1.962849e-02 -2.006093e-02 -2.049588e-02
## ASV7789      2.366578e-02  2.473761e-02  2.584969e-02  2.700292e-02
## ASV7809      4.802983e-03  5.031844e-03  5.267332e-03  5.509384e-03
## ASV8002     -2.426327e-02 -2.480878e-02 -2.535785e-02 -2.591041e-02
## ASV8205      1.504709e-02  1.556308e-02  1.609174e-02  1.663307e-02
## ASV9155     -4.758805e-03 -4.816013e-03 -4.870819e-03 -4.923140e-03
## ASV9221      1.161383e-02  1.222090e-02  1.285387e-02  1.351351e-02
## ASV9311     -3.896555e-02 -3.984670e-02 -4.073416e-02 -4.162774e-02
## ASV9557     -2.664065e-02 -2.724411e-02 -2.785196e-02 -2.846408e-02
## ASV9936     -5.374657e-02 -5.496604e-02 -5.619454e-02 -5.743180e-02
## ASV1445      4.666030e-02  4.818500e-02  4.974361e-02  5.133609e-02
## ASV4232      2.764687e-02  2.896274e-02  3.033741e-02  3.177298e-02
## ASV6479      1.765409e-02  1.856877e-02  1.952226e-02  2.051560e-02
## ASV0142     -2.339893e-02 -2.397387e-02 -2.455648e-02 -2.514677e-02
## ASV0378      1.894567e-02  1.961345e-02  2.029474e-02  2.098921e-02
## ASV1122      4.811027e-02  4.979266e-02  5.152032e-02  5.329380e-02
## ASV0123     -2.025534e-02 -2.073523e-02 -2.122024e-02 -2.171031e-02
## ASV2064      4.777123e-03  4.658952e-03  4.524766e-03  4.373955e-03
## ASV4459     -9.720149e-04 -1.036968e-03 -1.108577e-03 -1.187261e-03
## ASV0448      1.575550e-02  1.635562e-02  1.697219e-02  1.760520e-02
## ASV0397      2.347741e-02  2.417346e-02  2.488301e-02  2.560611e-02
## ASV0485      2.562620e-02  2.636385e-02  2.711547e-02  2.788107e-02
## ASV1566      3.971332e-02  4.088070e-02  4.206971e-02  4.328027e-02
## ASV1365      3.495023e-02  3.593864e-02  3.694098e-02  3.795710e-02
## ASV1065      5.191449e-02  5.353443e-02  5.518800e-02  5.687522e-02
## ASV0722     -4.614416e-03 -4.845257e-03 -5.087009e-03 -5.340087e-03
## ASV12660    -2.131192e-02 -2.179720e-02 -2.228683e-02 -2.278071e-02
## ASV0223      7.734093e-03  7.991087e-03  8.255501e-03  8.527483e-03
## ASV0229      1.456512e-02  1.511436e-02  1.568195e-02  1.626843e-02
## ASV0877     -2.238336e-03 -2.626710e-03 -3.045483e-03 -3.496125e-03
## ASV0983      2.329625e-02  2.387884e-02  2.446708e-02  2.506070e-02
## ASV0626      9.084154e-03  9.482801e-03  9.893282e-03  1.031571e-02
## ASV4146     -2.911861e-03 -3.247518e-03 -3.608484e-03 -3.995830e-03
## ASV4175     -3.826105e-02 -3.950223e-02 -4.076952e-02 -4.206274e-02
## ASV2082     -3.657437e-02 -3.835568e-02 -4.020690e-02 -4.212942e-02
## ASV2272      1.925120e-02  1.995238e-02  2.067486e-02  2.141907e-02
## ASV2245     -2.813396e-02 -2.905919e-02 -3.000404e-02 -3.096836e-02
## ASV0590     -3.774918e-02 -3.960842e-02 -4.154218e-02 -4.355221e-02
## ASV0217      1.128711e-02  1.187808e-02  1.249202e-02  1.312946e-02
## ASV0416      6.291800e-03  6.161087e-03  6.013734e-03  5.849265e-03
## ASV1056      2.950712e-02  3.052106e-02  3.155782e-02  3.261730e-02
## ASV7777     -3.935622e-02 -4.085880e-02 -4.241799e-02 -4.403618e-02
## ASV0455      5.631530e-03  5.770879e-03  5.909965e-03  6.048520e-03
## ASV0604      2.110930e-02  2.189088e-02  2.269404e-02  2.351897e-02
## ASV6100     -2.982006e-02 -3.101554e-02 -3.225611e-02 -3.354334e-02
## ASV11359    -5.197016e-02 -5.353063e-02 -5.511562e-02 -5.672445e-02
## ASV6604      8.820109e-03  9.112545e-03  9.408936e-03  9.708870e-03
## ASV5004     -1.940103e-02 -2.008606e-02 -2.079207e-02 -2.151949e-02
## ASV1483     -7.290779e-03 -7.493540e-03 -7.698299e-03 -7.904824e-03
## ASV9773     -2.665429e-02 -2.763697e-02 -2.865102e-02 -2.969722e-02
## ASV4059      7.837974e-03  8.235304e-03  8.642304e-03  9.058414e-03
## ASV1193      2.705710e-02  2.789569e-02  2.875214e-02  2.962646e-02
## ASV4610      3.321641e-03  3.511900e-03  3.703470e-03  3.895833e-03
## ASV0742      4.813067e-03  5.084215e-03  5.362010e-03  5.646223e-03
## ASV1502     -6.478396e-03 -6.775780e-03 -7.080727e-03 -7.393043e-03
## ASV0195     -2.437738e-03 -2.583222e-03 -2.734515e-03 -2.891743e-03
## ASV1213      1.087092e-02  1.100767e-02  1.113926e-02  1.126540e-02
## ASV1648     -2.714231e-02 -2.825353e-02 -2.940753e-02 -3.060569e-02
## ASV6984     -2.597828e-02 -2.706011e-02 -2.818436e-02 -2.935240e-02
## ASV0396      5.392814e-04  4.987968e-04  4.473909e-04  3.839624e-04
## ASV4297      1.870113e-02  1.908863e-02  1.947995e-02  1.987533e-02
## ASV2622      3.577570e-02  3.672348e-02  3.768643e-02  3.866460e-02
## ASV3512      3.325973e-02  3.486136e-02  3.653154e-02  3.827249e-02
## ASV2411      3.863864e-02  4.004869e-02  4.149387e-02  4.297392e-02
## ASV2291     -3.226305e-02 -3.376737e-02 -3.532444e-02 -3.693505e-02
## ASV0807      3.813156e-02  3.922412e-02  4.033590e-02  4.146708e-02
## ASV1292      4.609424e-03  4.680521e-03  4.754941e-03  4.833200e-03
## ASV1035      3.031449e-02  3.116888e-02  3.204259e-02  3.293610e-02
## ASV0070      4.770254e-03  5.045718e-03  5.333115e-03  5.632708e-03
## ASV0255     -2.706647e-04 -4.393595e-04 -6.228053e-04 -8.217578e-04
## ASV0057     -5.166420e-03 -5.192662e-03 -5.213465e-03 -5.228622e-03
## ASV0077     -9.082322e-05 -7.133772e-05 -5.347128e-05 -3.763840e-05
## ASV0625      1.473628e-02  1.504069e-02  1.534614e-02  1.565257e-02
## ASV2464      1.036435e-01  1.059959e-01  1.083687e-01  1.107613e-01
## ASV1315      5.188234e-02  5.382288e-02  5.581575e-02  5.786102e-02
## ASV2673      4.538516e-02  4.713499e-02  4.893739e-02  5.079301e-02
## ASV2161      1.987681e-02  2.069475e-02  2.154147e-02  2.241759e-02
## ASV0337     -9.200976e-03 -9.527264e-03 -9.862918e-03 -1.020809e-02
## ASV7680     -6.175850e-02 -6.393077e-02 -6.615881e-02 -6.844275e-02
## ASV0611      3.592999e-02  3.728154e-02  3.867619e-02  4.011492e-02
## ASV3118     -4.237030e-02 -4.399613e-02 -4.566922e-02 -4.739005e-02
## ASV1284     -1.909548e-02 -2.065795e-02 -2.231055e-02 -2.405679e-02
## ASV0889      2.070691e-02  2.139528e-02  2.210633e-02  2.284099e-02
## ASV4649     -1.207677e-02 -1.249310e-02 -1.292092e-02 -1.336041e-02
## ASV1108     -3.563104e-02 -3.710496e-02 -3.862704e-02 -4.019799e-02
## ASV0738      2.717383e-02  2.849852e-02  2.988016e-02  3.132067e-02
## ASV0473     -4.938936e-03 -5.055074e-03 -5.163994e-03 -5.264534e-03
## ASV0598     -1.687354e-02 -1.773832e-02 -1.863997e-02 -1.957942e-02
## ASV0429      1.091760e-02  1.109643e-02  1.127186e-02  1.144374e-02
## ASV1549      4.201348e-02  4.359808e-02  4.522453e-02  4.689263e-02
## ASV1203      2.078397e-02  2.132682e-02  2.187550e-02  2.242976e-02
## ASV4532      6.260501e-04  6.913963e-04  7.641657e-04  8.449429e-04
## ASV0274      5.647372e-03  5.798906e-03  5.948192e-03  6.094650e-03
## ASV0163     -1.387018e-02 -1.424875e-02 -1.463739e-02 -1.503655e-02
## ASV1298      2.804652e-03  3.024110e-03  3.261236e-03  3.517075e-03
## ASV9424     -5.253624e-02 -5.461322e-02 -5.676258e-02 -5.898620e-02
## ASV0412      3.528981e-02  3.623660e-02  3.719835e-02  3.817511e-02
## ASV0284      4.335919e-04  1.820472e-04 -9.085219e-05 -3.861657e-04
## ASV0620     -1.736886e-02 -1.814918e-02 -1.895752e-02 -1.979445e-02
## ASV0153     -5.467659e-02 -5.668826e-02 -5.875146e-02 -6.086612e-02
## ASV0498      1.455447e-02  1.492528e-02  1.529516e-02  1.566343e-02
## ASV0097      1.104179e-02  1.145777e-02  1.188465e-02  1.232235e-02
## ASV0104     -5.128009e-02 -5.266917e-02 -5.407559e-02 -5.549882e-02
## ASV1282      1.021502e-02  1.018257e-02  1.012748e-02  1.004845e-02
## ASV3883     -2.440340e-02 -2.531819e-02 -2.625302e-02 -2.720733e-02
## ASV0801      9.898713e-03  1.032027e-02  1.076041e-02  1.121992e-02
## ASV1611     -4.808289e-02 -4.991551e-02 -5.180271e-02 -5.374516e-02
## ASV0227     -1.512091e-02 -1.582544e-02 -1.655663e-02 -1.731515e-02
## ASV0833      1.347141e-02  1.391082e-02  1.436031e-02  1.481997e-02
## ASV0718      6.093613e-02  6.297207e-02  6.505638e-02  6.718924e-02
## ASV1139     -3.849110e-03 -4.275355e-03 -4.724421e-03 -5.196776e-03
## ASV0766     -1.228519e-02 -1.275328e-02 -1.323268e-02 -1.372323e-02
## ASV2091      2.988724e-02  3.042929e-02  3.096687e-02  3.149958e-02
## ASV1238     -5.794029e-02 -6.046432e-02 -6.309291e-02 -6.582968e-02
## ASV9193     -1.624964e-02 -1.715896e-02 -1.810995e-02 -1.910376e-02
## ASV0290      2.307850e-03  2.378881e-03  2.456769e-03  2.542047e-03
## ASV0231      1.281166e-02  1.307474e-02  1.333448e-02  1.359034e-02
## ASV0185      2.033649e-02  2.130676e-02  2.231643e-02  2.336659e-02
## ASV2330      1.162112e-02  1.185578e-02  1.209386e-02  1.233560e-02
## ASV3119     -1.743970e-02 -1.824747e-02 -1.908650e-02 -1.995752e-02
## ASV2368     -3.349671e-02 -3.500576e-02 -3.657624e-02 -3.820996e-02
## ASV0122     -9.267647e-03 -9.536758e-03 -9.811389e-03 -1.009164e-02
## ASV1044      3.521678e-02  3.660856e-02  3.804726e-02  3.953399e-02
## ASV0160     -7.431613e-03 -7.624891e-03 -7.824525e-03 -8.030935e-03
## ASV0326      2.533469e-03  2.574922e-03  2.613734e-03  2.649621e-03
## ASV1388      4.776216e-02  4.907422e-02  5.040533e-02  5.175525e-02
## ASV0792      2.957213e-02  3.023576e-02  3.090304e-02  3.157375e-02
## ASV0036     -1.578282e-02 -1.632232e-02 -1.687185e-02 -1.743105e-02
## ASV2125      3.564731e-02  3.664257e-02  3.765059e-02  3.867087e-02
## ASV1075     -1.463769e-03 -1.561912e-03 -1.666149e-03 -1.776742e-03
## ASV0390      3.036671e-02  3.167393e-02  3.303114e-02  3.443972e-02
## ASV3790     -3.403542e-02 -3.525850e-02 -3.651627e-02 -3.780920e-02
## ASV1535     -1.524859e-02 -1.588893e-02 -1.654829e-02 -1.722673e-02
## ASV0263      3.713052e-02  3.833161e-02  3.955957e-02  4.081446e-02
## ASV0675      6.596418e-02  6.838301e-02  7.087010e-02  7.342618e-02
## ASV3348      6.609314e-03  6.857995e-03  7.112219e-03  7.371816e-03
## ASV0058     -1.366762e-02 -1.402359e-02 -1.438335e-02 -1.474674e-02
## ASV4142      1.611871e-02  1.649907e-02  1.688516e-02  1.727717e-02
## ASV0059     -1.036564e-02 -1.061842e-02 -1.087333e-02 -1.113029e-02
## ASV0013     -2.298452e-02 -2.370970e-02 -2.445090e-02 -2.520824e-02
## ASV0033     -1.369363e-02 -1.417146e-02 -1.465948e-02 -1.515750e-02
## ASV4354     -1.544517e-02 -1.600788e-02 -1.658605e-02 -1.717973e-02
## ASV0022     -1.172393e-02 -1.214308e-02 -1.257187e-02 -1.301016e-02
## ASV0134     -1.488488e-02 -1.558029e-02 -1.630648e-02 -1.706469e-02
## ASV0415      2.697834e-03  2.794546e-03  2.893148e-03  2.993636e-03
## ASV10103    -6.278100e-02 -6.507624e-02 -6.743364e-02 -6.985351e-02
## ASV1613      2.629404e-02  2.675195e-02  2.719998e-02  2.763726e-02
## ASV0135     -2.329546e-03 -2.336827e-03 -2.341363e-03 -2.343047e-03
## ASV0469     -4.455372e-02 -4.593170e-02 -4.734378e-02 -4.879062e-02
## ASV0471      3.059286e-02  3.164036e-02  3.272019e-02  3.383338e-02
## ASV0451     -1.196290e-02 -1.250261e-02 -1.305942e-02 -1.363341e-02
## ASV0747      1.760310e-02  1.813492e-02  1.867457e-02  1.922176e-02
## ASV1314     -2.565420e-02 -2.675921e-02 -2.790569e-02 -2.909469e-02
## ASV0425     -4.400623e-02 -4.503165e-02 -4.606792e-02 -4.711500e-02
## ASV0559     -1.775155e-02 -1.848911e-02 -1.925614e-02 -2.005348e-02
## ASV0148      2.629580e-03  2.905373e-03  3.198223e-03  3.508817e-03
## ASV0129      1.503631e-02  1.586717e-02  1.673490e-02  1.764046e-02
## ASV1072     -3.613868e-05 -1.590352e-04 -2.901913e-04 -4.297672e-04
## ASV2390      1.522391e-02  1.525763e-02  1.527217e-02  1.526690e-02
## ASV0548      1.931535e-02  1.987821e-02  2.045089e-02  2.103334e-02
## ASV0168     -9.041886e-03 -9.297937e-03 -9.558975e-03 -9.825057e-03
## ASV0066     -9.699240e-03 -9.914652e-03 -1.012848e-02 -1.034030e-02
## ASV0468     -7.228687e-03 -7.505059e-03 -7.791384e-03 -8.087989e-03
## ASV0172     -4.906825e-05  5.580382e-05  1.685861e-04  2.895734e-04
## ASV0236      1.201593e-02  1.272643e-02  1.346627e-02  1.423592e-02
## ASV0250      3.070296e-02  3.213528e-02  3.362603e-02  3.517690e-02
## ASV0338      8.646569e-03  8.877825e-03  9.108818e-03  9.339096e-03
## ASV0450     -4.617647e-03 -4.859259e-03 -5.110961e-03 -5.372940e-03
## ASV0377      1.210658e-02  1.237695e-02  1.264527e-02  1.291099e-02
## ASV1022      1.181648e-03  1.313731e-03  1.456181e-03  1.609586e-03
## ASV6174     -1.844681e-03 -1.903159e-03 -1.957488e-03 -2.006793e-03
## ASV0786     -5.910466e-03 -6.144529e-03 -6.381780e-03 -6.621776e-03
## ASV0053     -1.653237e-02 -1.705578e-02 -1.759023e-02 -1.813575e-02
## ASV0697     -8.126644e-03 -8.378210e-03 -8.638419e-03 -8.907802e-03
## ASV0785      1.797069e-02  1.848390e-02  1.900815e-02  1.954381e-02
## ASV1967     -1.789406e-02 -1.840786e-02 -1.893035e-02 -1.946140e-02
## ASV0385      8.325034e-03  8.565083e-03  8.805035e-03  9.044345e-03
## ASV0295      5.732971e-03  6.053856e-03  6.389298e-03  6.739719e-03
## ASV0072     -1.116804e-02 -1.135711e-02 -1.154109e-02 -1.171952e-02
## ASV0157      5.210643e-03  5.618760e-03  6.050068e-03  6.505433e-03
## ASV0501      3.544271e-02  3.649179e-02  3.755515e-02  3.863223e-02
## ASV10729    -4.985729e-02 -5.160070e-02 -5.338976e-02 -5.522490e-02
## ASV1470      1.047487e-02  1.045514e-02  1.041587e-02  1.035602e-02
## ASV0050     -3.257410e-02 -3.343310e-02 -3.430156e-02 -3.517910e-02
## ASV0411     -1.157554e-02 -1.206084e-02 -1.256567e-02 -1.309078e-02
## ASV0549      1.613237e-02  1.669535e-02  1.727194e-02  1.786211e-02
## ASV0184      5.160552e-03  5.375994e-03  5.601216e-03  5.836706e-03
## ASV0705      5.976296e-03  6.047451e-03  6.112178e-03  6.169916e-03
## ASV1715      1.952578e-02  2.014112e-02  2.076925e-02  2.141018e-02
## ASV0603      5.422616e-03  5.715477e-03  6.023742e-03  6.348034e-03
## ASV0826      3.080312e-02  3.176151e-02  3.274227e-02  3.374576e-02
## ASV0034     -7.859266e-03 -8.033839e-03 -8.208726e-03 -8.383823e-03
## ASV0838     -1.193836e-02 -1.305086e-02 -1.423692e-02 -1.549990e-02
## ASV0614     -8.316023e-03 -8.569725e-03 -8.829139e-03 -9.094372e-03
## ASV0014     -2.223759e-02 -2.289236e-02 -2.355839e-02 -2.423556e-02
## ASV0585     -6.894684e-03 -7.306025e-03 -7.729731e-03 -8.165446e-03
## ASV0016     -2.329521e-02 -2.398428e-02 -2.468550e-02 -2.539875e-02
## ASV5394     -1.901520e-02 -1.958207e-02 -2.015455e-02 -2.073178e-02
## ASV0666      2.957380e-02  3.025229e-02  3.093618e-02  3.162537e-02
## ASV2085     -7.613063e-03 -8.315932e-03 -9.057737e-03 -9.839849e-03
## ASV0003     -1.585753e-02 -1.632881e-02 -1.680876e-02 -1.729735e-02
## ASV0346      1.027763e-02  1.060832e-02  1.094381e-02  1.128387e-02
## ASV0267      2.277501e-03  2.341913e-03  2.401128e-03  2.454244e-03
## ASV0353      1.680993e-02  1.743142e-02  1.807015e-02  1.872622e-02
## ASV2419      3.162838e-02  3.246069e-02  3.329838e-02  3.414043e-02
## ASV0447      2.466041e-02  2.557711e-02  2.652128e-02  2.749347e-02
## ASV0654      2.736661e-02  2.815280e-02  2.895118e-02  2.976158e-02
## ASV0151      8.227098e-03  8.600436e-03  8.986045e-03  9.383980e-03
## ASV0065     -9.946565e-03 -1.022514e-02 -1.050842e-02 -1.079644e-02
## ASV0527      2.583759e-02  2.658603e-02  2.734586e-02  2.811673e-02
## ASV4055     -9.977046e-03 -1.056265e-02 -1.118287e-02 -1.183959e-02
## ASV0166     -1.020803e-02 -1.044550e-02 -1.068598e-02 -1.092963e-02
## ASV0417     -2.157633e-03 -2.140036e-03 -2.119385e-03 -2.095767e-03
## ASV0078     -5.571702e-03 -5.644524e-03 -5.712084e-03 -5.773932e-03
## ASV0322      4.713933e-03  5.099507e-03  5.507178e-03  5.937646e-03
## ASV0156     -2.334231e-02 -2.422673e-02 -2.514076e-02 -2.608527e-02
## ASV0648     -5.017800e-02 -5.194850e-02 -5.376217e-02 -5.561875e-02
## ASV0407     -5.042360e-03 -5.271541e-03 -5.510169e-03 -5.758540e-03
## ASV2030     -9.760910e-03 -1.023764e-02 -1.073637e-02 -1.125775e-02
## ASV0300      6.682889e-03  6.922724e-03  7.167939e-03  7.418449e-03
## ASV1150      2.048132e-03  2.114817e-03  2.181217e-03  2.247089e-03
## ASV0958      2.362701e-02  2.464172e-02  2.569405e-02  2.678495e-02
## ASV0216     -1.793724e-02 -1.862723e-02 -1.934456e-02 -2.009028e-02
## ASV0446      2.981210e-02  3.081267e-02  3.183502e-02  3.287899e-02
## ASV0367     -1.854818e-02 -1.916838e-02 -1.980305e-02 -2.045220e-02
## ASV0200     -1.030101e-02 -1.059992e-02 -1.090161e-02 -1.120568e-02
## ASV0334     -1.728899e-03 -1.755281e-03 -1.785753e-03 -1.820864e-03
## ASV1311      1.364403e-03  1.246504e-03  1.117524e-03  9.770038e-04
## ASV0458      2.461465e-03  2.357196e-03  2.243055e-03  2.118783e-03
## ASV1371      1.980714e-03  2.021949e-03  2.061248e-03  2.098384e-03
## ASV0418      1.644546e-02  1.681858e-02  1.719449e-02  1.757316e-02
## ASV0004      2.180632e-03  2.223028e-03  2.265306e-03  2.307438e-03
## ASV1943      2.126978e-02  2.118686e-02  2.108194e-02  2.095499e-02
## ASV1495     -1.558484e-02 -1.641097e-02 -1.727182e-02 -1.816814e-02
## ASV0901     -2.566482e-02 -2.672089e-02 -2.781627e-02 -2.895212e-02
## ASV0628      4.102425e-03  4.039955e-03  3.965154e-03  3.877337e-03
## ASV0400      3.523312e-03  3.513029e-03  3.493198e-03  3.463088e-03
## ASV0116     -7.201136e-03 -7.480704e-03 -7.769432e-03 -8.067517e-03
## ASV0788      6.576064e-02  6.841647e-02  7.116915e-02  7.402181e-02
## ASV0117      5.526003e-03  5.749479e-03  5.980187e-03  6.218285e-03
## ASV3137     -6.695261e-04 -6.611057e-04 -6.494898e-04 -6.343597e-04
## ASV0001      2.198013e-03  2.238832e-03  2.279939e-03  2.321392e-03
## ASV1651      7.220744e-03  7.397307e-03  7.577698e-03  7.762202e-03
## ASV1692      5.255357e-02  5.458307e-02  5.668085e-02  5.884891e-02
## ASV0660      3.857675e-03  3.639464e-03  3.399427e-03  3.136873e-03
## ASV0508      5.966907e-05  3.171246e-05  4.438590e-07 -3.441049e-05
## ASV1660     -1.311359e-02 -1.360216e-02 -1.410072e-02 -1.460887e-02
## ASV0233      1.375737e-02  1.422174e-02  1.469828e-02  1.518720e-02
## ASV1343     -2.975098e-02 -3.090763e-02 -3.210338e-02 -3.333922e-02
## ASV0209      7.100051e-03  7.188032e-03  7.270571e-03  7.347253e-03
## ASV0193     -8.504239e-03 -8.601399e-03 -8.691005e-03 -8.772541e-03
## ASV0357      1.287866e-02  1.356060e-02  1.427433e-02  1.502088e-02
## ASV0198      9.748448e-03  1.006432e-02  1.038918e-02  1.072328e-02
## ASV0007      1.583876e-03  1.600729e-03  1.617198e-03  1.633335e-03
## ASV1772      3.584383e-03  4.133586e-03  4.732322e-03  5.383974e-03
## ASV0009      1.021456e-03  1.021991e-03  1.022025e-03  1.021638e-03
## ASV0006     -4.079788e-03 -4.239586e-03 -4.403973e-03 -4.572971e-03
## ASV0011     -1.144122e-02 -1.185182e-02 -1.227396e-02 -1.270780e-02
## ASV0015      6.065202e-04  5.895634e-04  5.705182e-04  5.493000e-04
## ASV0017      8.348202e-04  8.278565e-04  8.193215e-04  8.091549e-04
## ASV0235     -1.105358e-02 -1.147366e-02 -1.190784e-02 -1.235651e-02
## ASV0382      5.919377e-03  5.976878e-03  6.023084e-03  6.056952e-03
## ASV2357      3.504935e-02  3.633798e-02  3.766350e-02  3.902617e-02
## ASV0567     -8.602596e-03 -9.008335e-03 -9.432582e-03 -9.876025e-03
## ASV0165      5.361592e-03  5.535304e-03  5.712718e-03  5.893850e-03
## ASV0005      6.516650e-03  6.694026e-03  6.873303e-03  7.054373e-03
## ASV0384      3.020184e-03  3.251548e-03  3.496700e-03  3.756247e-03
## ASV0002      1.099742e-03  1.131594e-03  1.164081e-03  1.197198e-03
## ASV3017      2.545528e-02  2.593014e-02  2.640109e-02  2.686772e-02
## ASV0091     -1.422082e-03 -1.506085e-03 -1.595682e-03 -1.691209e-03
## ASV0186     -1.339986e-02 -1.375408e-02 -1.411038e-02 -1.446840e-02
## ASV0370      6.654099e-03  6.854792e-03  7.061242e-03  7.273720e-03
## ASV0018      8.690489e-03  8.941309e-03  9.195942e-03  9.454310e-03
## ASV1377      6.870706e-02  7.027550e-02  7.185376e-02  7.344148e-02
## ASV0019      9.267607e-03  9.541696e-03  9.820471e-03  1.010388e-02
## ASV0023     -7.045956e-03 -7.282968e-03 -7.524748e-03 -7.771206e-03
## ASV2194      1.389706e-02  1.448366e-02  1.509160e-02  1.572137e-02
## ASV1155      3.287772e-02  3.390283e-02  3.495752e-02  3.604291e-02
## ASV0510     -5.458686e-03 -5.573866e-03 -5.692681e-03 -5.815312e-03
## ASV2371     -1.825270e-02 -1.870858e-02 -1.916825e-02 -1.963145e-02
## ASV0024     -8.671912e-03 -8.964473e-03 -9.263214e-03 -9.568063e-03
## ASV2452      1.093364e-02  1.096099e-02  1.097621e-02  1.097896e-02
## ASV2332     -5.934703e-02 -6.115913e-02 -6.301253e-02 -6.490767e-02
## ASV2591      2.605506e-02  2.693602e-02  2.783121e-02  2.874012e-02
## ASV0521      1.840869e-02  1.908990e-02  1.979150e-02  2.051386e-02
## ASV5542      1.641475e-02  1.697858e-02  1.755737e-02  1.815134e-02
## ASV0336     -5.353525e-03 -5.629925e-03 -5.919465e-03 -6.222777e-03
## ASV10102     3.012848e-02  3.111660e-02  3.212516e-02  3.315401e-02
## ASV16823    -2.793712e-02 -2.856675e-02 -2.920263e-02 -2.984473e-02
## ASV3104      1.445406e-01  1.477974e-01  1.510864e-01  1.544076e-01
## ASV0781      3.028308e-02  3.130744e-02  3.236145e-02  3.344581e-02
## ASV10899     3.457089e-02  3.615429e-02  3.779800e-02  3.950350e-02
## ASV11222    -4.916429e-02 -5.027172e-02 -5.139011e-02 -5.251942e-02
## ASV11327    -4.413761e-02 -4.513163e-02 -4.613546e-02 -4.714910e-02
## ASV12458    -4.915734e-02 -5.026422e-02 -5.138203e-02 -5.251074e-02
## ASV1636      3.376887e-02  3.467758e-02  3.560166e-02  3.654125e-02
## ASV1890     -1.739022e-02 -1.771866e-02 -1.805439e-02 -1.839816e-02
## ASV2898      4.575655e-02  4.700990e-02  4.828691e-02  4.958803e-02
## ASV8328      3.257312e-02  3.430356e-02  3.610360e-02  3.797443e-02
## ASV0709     -5.467507e-02 -5.619001e-02 -5.772788e-02 -5.928836e-02
## ASV0856      6.568625e-02  6.808262e-02  7.054094e-02  7.306129e-02
## ASV0909      3.559339e-02  3.725694e-02  3.898044e-02  4.076496e-02
## ASV0937     -4.712574e-02 -4.905907e-02 -5.106278e-02 -5.313856e-02
## ASV11390    -7.014619e-02 -7.172502e-02 -7.331946e-02 -7.492947e-02
## ASV11966     3.477819e-02  3.605285e-02  3.735841e-02  3.869473e-02
## ASV12990     1.368653e-02  1.403403e-02  1.438728e-02  1.474630e-02
## ASV14797     1.940886e-02  1.988512e-02  2.036897e-02  2.086052e-02
## ASV14904    -1.006494e-01 -1.029143e-01 -1.052017e-01 -1.075114e-01
## ASV15304     2.553603e-02  2.652207e-02  2.753317e-02  2.856919e-02
## ASV16696    -3.477477e-02 -3.555731e-02 -3.634759e-02 -3.714561e-02
## ASV1690      1.032059e-01  1.065273e-01  1.099044e-01  1.133358e-01
## ASV2029      5.556310e-02  5.723563e-02  5.894322e-02  6.068605e-02
## ASV2834      8.118118e-02  8.376409e-02  8.639705e-02  8.907963e-02
## ASV4003      1.040603e-01  1.089052e-01  1.139607e-01  1.192346e-01
## ASV4064      4.090090e-02  4.231779e-02  4.377317e-02  4.526778e-02
## ASV4294      4.032991e-02  4.216144e-02  4.406279e-02  4.603565e-02
## ASV4609      1.964736e-02  2.031483e-02  2.100211e-02  2.170954e-02
## ASV6283     -3.250490e-02 -3.323632e-02 -3.397500e-02 -3.472092e-02
## ASV6491     -4.658877e-02 -4.763716e-02 -4.869597e-02 -4.976518e-02
## ASV7453      4.797256e-02  4.977667e-02  5.162699e-02  5.352348e-02
## ASV7959      2.774719e-02  2.907710e-02  3.046097e-02  3.190040e-02
## ASV8219      4.026233e-01  4.116849e-01  4.208367e-01  4.300788e-01
## ASV8547     -4.171069e-02 -4.264954e-02 -4.359777e-02 -4.455536e-02
## ASV9319      3.595971e-02  3.741364e-02  3.891944e-02  4.047856e-02
## ASV9382     -8.161301e-02 -8.345027e-02 -8.530590e-02 -8.717991e-02
## ASV11516    -5.451155e-02 -5.573888e-02 -5.697852e-02 -5.823046e-02
## ASV14377    -3.936090e-02 -4.024726e-02 -4.114252e-02 -4.204668e-02
## ASV1867      5.324644e-02  5.520133e-02  5.721675e-02  5.929414e-02
## ASV1895      8.797082e-03  8.669831e-03  8.520987e-03  8.349850e-03
## ASV3168      1.801248e-02  1.831697e-02  1.861778e-02  1.891466e-02
## ASV4449      1.640301e-01  1.697430e-01  1.756250e-01  1.816802e-01
## ASV6596      5.588086e-02  5.836500e-02  6.094055e-02  6.360930e-02
## ASV7492      1.091501e-02  1.164950e-02  1.241441e-02  1.321005e-02
## ASV9854     -7.851949e-03 -8.013161e-03 -8.175121e-03 -8.337835e-03
## ASV6296      6.605418e-01  6.754236e-01  6.904560e-01  7.056388e-01
## ASV4201      2.610507e-02  2.758135e-02  2.912704e-02  3.074452e-02
## ASV0552      3.419151e-02  3.529396e-02  3.641671e-02  3.755922e-02
## ASV3671     -2.455985e-02 -2.562916e-02 -2.674603e-02 -2.791225e-02
## ASV3529      4.775334e-03  5.059034e-03  5.348171e-03  5.642308e-03
## ASV1060      1.320568e-02  1.382456e-02  1.447092e-02  1.514581e-02
## ASV0239     -5.968428e-03 -6.033441e-03 -6.094318e-03 -6.150756e-03
## ASV5711     -4.550351e-02 -4.685313e-02 -4.822850e-02 -4.962945e-02
## ASV4152     -7.491082e-02 -7.729020e-02 -7.971480e-02 -8.218394e-02
## ASV1461      2.049116e-02  2.078365e-02  2.106965e-02  2.134881e-02
## ASV2877      1.084489e-02  1.095894e-02  1.106346e-02  1.115778e-02
## ASV0012      3.379613e-03  3.492636e-03  3.608475e-03  3.727154e-03
## ASV9823     -4.157071e-03 -4.580897e-03 -5.029895e-03 -5.504848e-03
## ASV0008      3.498923e-03  3.614780e-03  3.733543e-03  3.855237e-03
## ASV7832     -4.857629e-02 -5.030352e-02 -5.207696e-02 -5.389705e-02
## ASV1915     -6.268035e-03 -6.544126e-03 -6.831919e-03 -7.131787e-03
## ASV0055     -7.001829e-03 -7.322128e-03 -7.654910e-03 -8.000526e-03
## ASV0032      3.248100e-04  3.198244e-04  3.160558e-04  3.137747e-04
## ASV2977     -5.985576e-02 -6.167720e-02 -6.352880e-02 -6.540987e-02
## ASV0466      2.645703e-02  2.675290e-02  2.703242e-02  2.729478e-02
## ASV3866      4.214510e-02  4.382218e-02  4.555804e-02  4.735421e-02
## ASV0040      1.295449e-02  1.339208e-02  1.384011e-02  1.429860e-02
## ASV0496     -1.208065e-02 -1.267999e-02 -1.329946e-02 -1.393909e-02
## ASV0052      1.112280e-02  1.151928e-02  1.192781e-02  1.234870e-02
## ASV3828     -2.280783e-02 -2.329770e-02 -2.379108e-02 -2.428794e-02
## ASV1930      1.194847e-02  1.216264e-02  1.237471e-02  1.258451e-02
## ASV2126      2.833927e-02  2.923270e-02  3.014847e-02  3.108697e-02
## ASV0793      4.414096e-02  4.575221e-02  4.741239e-02  4.912277e-02
## ASV0299     -3.909350e-03 -4.209534e-03 -4.529764e-03 -4.870988e-03
## ASV0208      3.056418e-02  3.169211e-02  3.285629e-02  3.405764e-02
## ASV0511     -5.978644e-03 -6.097892e-03 -6.220701e-03 -6.347383e-03
## ASV1123     -1.911880e-02 -1.935360e-02 -1.957314e-02 -1.977602e-02
## ASV0099      3.032012e-03  3.202691e-03  3.381397e-03  3.568357e-03
## ASV0752     -2.645212e-02 -2.751794e-02 -2.862023e-02 -2.975986e-02
## ASV0883      3.339823e-02  3.458225e-02  3.579300e-02  3.703017e-02
## ASV0683      4.299833e-02  4.460165e-02  4.625120e-02  4.794751e-02
## ASV4117     -6.308007e-02 -6.540722e-02 -6.780542e-02 -7.027606e-02
## ASV2172     -1.421111e-03 -1.632860e-03 -1.859371e-03 -2.101289e-03
## ASV0330     -1.237644e-02 -1.285627e-02 -1.335289e-02 -1.386681e-02
## ASV0728      4.918052e-02  5.072344e-02  5.230285e-02  5.391943e-02
## ASV0499      1.751898e-02  1.819686e-02  1.889568e-02  1.961577e-02
## ASV0120     -2.124282e-02 -2.183807e-02 -2.243945e-02 -2.304642e-02
## ASV1446      3.071198e-04 -1.832670e-04 -7.120601e-04 -1.280865e-03
## ASV17171    -4.731052e-02 -4.903887e-02 -5.082097e-02 -5.265780e-02
## ASV0533      5.196531e-03  5.409562e-03  5.628969e-03  5.854785e-03
## ASV2495     -2.200191e-02 -2.300057e-02 -2.403233e-02 -2.509738e-02
## ASV5582      5.821342e-03  5.624880e-03  5.403317e-03  5.155195e-03
## ASV1488      3.983068e-03  3.960929e-03  3.928530e-03  3.885256e-03
## ASV0682      1.279079e-02  1.326720e-02  1.375612e-02  1.425753e-02
## ASV0068     -1.640484e-02 -1.685617e-02 -1.731067e-02 -1.776782e-02
## ASV1987     -5.837986e-02 -6.065833e-02 -6.300577e-02 -6.542304e-02
## ASV0035     -1.208150e-02 -1.280026e-02 -1.355624e-02 -1.435083e-02
## ASV7192     -2.190709e-02 -2.245324e-02 -2.300176e-02 -2.355210e-02
## ASV0873     -8.478190e-02 -8.899119e-02 -9.333164e-02 -9.780344e-02
## ASV4749     -2.055932e-02 -2.174081e-02 -2.297224e-02 -2.425468e-02
## ASV2174      5.988160e-03  5.853077e-03  5.700899e-03  5.531152e-03
## ASV1476     -2.646206e-02 -2.754310e-02 -2.866036e-02 -2.981460e-02
## ASV0740     -7.163171e-02 -7.453290e-02 -7.753640e-02 -8.064486e-02
## ASV0170     -1.131678e-02 -1.171510e-02 -1.212507e-02 -1.254695e-02
## ASV2466     -5.344350e-02 -5.536837e-02 -5.734861e-02 -5.938492e-02
## ASV1709      2.065203e-02  2.166422e-02  2.273333e-02  2.386248e-02
## ASV6170     -9.103624e-02 -9.441002e-02 -9.787997e-02 -1.014469e-01
## ASV3673      4.761611e-02  4.942781e-02  5.129154e-02  5.320766e-02
## ASV1745     -1.537638e-02 -1.602659e-02 -1.669850e-02 -1.739245e-02
##                                                                    
## (Intercept)  2.817601e-01  2.898402e-01  2.980431e-01  3.063664e-01
## ASV1236      4.402785e-02  4.513310e-02  4.625343e-02  4.738876e-02
## ASV0421      1.487765e-02  1.545069e-02  1.603574e-02  1.663256e-02
## ASV0691     -1.733245e-02 -1.744507e-02 -1.755031e-02 -1.764806e-02
## ASV0899      3.543617e-02  3.621086e-02  3.699281e-02  3.778219e-02
## ASV1004      8.660154e-02  8.867839e-02  9.077856e-02  9.290175e-02
## ASV1041     -2.743904e-02 -2.771842e-02 -2.797799e-02 -2.821687e-02
## ASV1058      5.517934e-02  5.657580e-02  5.799244e-02  5.942917e-02
## ASV12542     1.887220e-02  1.935086e-02  1.984031e-02  2.034086e-02
## ASV1294      5.273560e-02  5.415174e-02  5.559574e-02  5.706809e-02
## ASV13113     3.520403e-02  3.669326e-02  3.823551e-02  3.983194e-02
## ASV1318      5.066791e-02  5.194128e-02  5.323527e-02  5.455022e-02
## ASV2269     -7.945233e-02 -8.104221e-02 -8.263288e-02 -8.422360e-02
## ASV2542      6.888072e-02  7.141193e-02  7.401772e-02  7.669922e-02
## ASV2660     -3.161152e-02 -3.229711e-02 -3.298845e-02 -3.368546e-02
## ASV2737      9.163192e-03  9.377130e-03  9.595818e-03  9.819402e-03
## ASV2840      3.132610e-02  3.168714e-02  3.203688e-02  3.237511e-02
## ASV3053      2.112041e-01  2.160733e-01  2.210042e-01  2.259965e-01
## ASV3077      1.474687e-02  1.514325e-02  1.554803e-02  1.596137e-02
## ASV3134      5.110845e-02  5.318362e-02  5.532927e-02  5.754680e-02
## ASV3140      4.733462e-02  4.872436e-02  5.013769e-02  5.157429e-02
## ASV3579      2.891832e-02  3.005629e-02  3.122368e-02  3.242032e-02
## ASV6119     -2.175412e-02 -2.219365e-02 -2.263370e-02 -2.307398e-02
## ASV7557     -4.421971e-02 -4.511485e-02 -4.601104e-02 -4.690765e-02
## ASV8422      1.167206e-02  1.199862e-02  1.233390e-02  1.267822e-02
## ASV1086     -1.485275e-03 -1.543031e-03 -1.603549e-03 -1.666944e-03
## ASV1310      2.213051e-02  2.261188e-02  2.309477e-02  2.357892e-02
## ASV15750    -8.651337e-04 -8.108379e-04 -7.520202e-04 -6.885033e-04
## ASV16905    -9.103384e-03 -9.288670e-03 -9.474126e-03 -9.659593e-03
## ASV2033      6.816536e-02  7.051886e-02  7.293334e-02  7.540981e-02
## ASV2089      1.922968e-02  1.961847e-02  2.000723e-02  2.039559e-02
## ASV2127      6.823546e-02  6.992278e-02  7.163300e-02  7.336598e-02
## ASV2725      4.713396e-02  4.809536e-02  4.906161e-02  5.003260e-02
## ASV2804     -1.885851e-02 -1.924294e-02 -1.962756e-02 -2.001200e-02
## ASV3075      6.567979e-02  6.808040e-02  7.055673e-02  7.311015e-02
## ASV3327      9.302598e-02  9.613330e-02  9.931715e-02  1.025785e-01
## ASV3342      7.925848e-02  8.197449e-02  8.476290e-02  8.762463e-02
## ASV3532     -8.520905e-02 -8.828200e-02 -9.145596e-02 -9.473360e-02
## ASV3600      3.852395e-02  3.977185e-02  4.104804e-02  4.235260e-02
## ASV4013      5.744432e-02  5.892595e-02  6.042384e-02  6.193742e-02
## ASV4136      5.216969e-02  5.344446e-02  5.473729e-02  5.604806e-02
## ASV4195      1.926697e-01  1.965995e-01  2.005290e-01  2.044545e-01
## ASV4407     -7.445697e-02 -7.597510e-02 -7.749286e-02 -7.900883e-02
## ASV4717      9.835377e-03  1.006738e-02  1.030734e-02  1.055571e-02
## ASV6794      3.020425e-02  3.097700e-02  3.176645e-02  3.257301e-02
## ASV8324     -3.822530e-02 -3.900497e-02 -3.978430e-02 -4.056260e-02
## ASV8981      5.013649e-03  5.324055e-03  5.647072e-03  5.982862e-03
## ASV9859      4.145170e-02  4.348430e-02  4.560455e-02  4.781513e-02
## ASV0936      5.479297e-02  5.640597e-02  5.804459e-02  5.970839e-02
## ASV12683    -2.450114e-04 -2.087121e-04 -1.673269e-04 -1.205388e-04
## ASV1293      2.540394e-02  2.597314e-02  2.654723e-02  2.712613e-02
## ASV13055     3.543985e-03  3.763953e-03  3.993787e-03  4.233755e-03
## ASV17063    -1.984398e-02 -2.024750e-02 -2.065072e-02 -2.105335e-02
## ASV2228      1.618562e-02  1.651480e-02  1.684379e-02  1.717237e-02
## ASV2769      6.811367e-03  7.035988e-03  7.262673e-03  7.491134e-03
## ASV2803      1.436992e-02  1.465326e-02  1.494042e-02  1.523152e-02
## ASV2896      2.790748e-02  2.909906e-02  3.033909e-02  3.162930e-02
## ASV3062      3.681854e-02  3.819922e-02  3.961508e-02  4.106607e-02
## ASV3107      4.374532e-02  4.529314e-02  4.688322e-02  4.851601e-02
## ASV3265      3.531464e-02  3.607243e-02  3.683443e-02  3.760034e-02
## ASV3666     -8.659207e-04 -9.239790e-04 -9.839978e-04 -1.045971e-03
## ASV4497      1.386945e-02  1.422560e-02  1.458717e-02  1.495413e-02
## ASV6914     -5.327963e-03 -5.538061e-03 -5.753396e-03 -5.973962e-03
## ASV0576     -3.105091e-02 -3.148441e-02 -3.191179e-02 -3.233266e-02
## ASV0673      5.682404e-02  5.838126e-02  5.996828e-02  6.158555e-02
## ASV0772      3.017043e-02  3.113834e-02  3.213178e-02  3.315120e-02
## ASV0862      1.405055e-02  1.460540e-02  1.516938e-02  1.574206e-02
## ASV0898      2.971939e-02  3.071458e-02  3.173311e-02  3.277526e-02
## ASV0910      3.330654e-02  3.448084e-02  3.568689e-02  3.692505e-02
## ASV0964     -1.285568e-02 -1.307359e-02 -1.329194e-02 -1.351068e-02
## ASV10059     2.887723e-02  2.998036e-02  3.111479e-02  3.228074e-02
## ASV10263    -3.024533e-02 -3.086278e-02 -3.148062e-02 -3.209860e-02
## ASV1088      6.030272e-02  6.257960e-02  6.493046e-02  6.735690e-02
## ASV1101      4.314955e-02  4.407929e-02  4.501560e-02  4.595835e-02
## ASV1183      1.714854e-02  1.772874e-02  1.832587e-02  1.894038e-02
## ASV11956     8.898087e-03  9.100059e-03  9.307089e-03  9.519310e-03
## ASV12774    -3.539739e-03 -3.733679e-03 -3.934119e-03 -4.141123e-03
## ASV1321      8.818577e-02  9.120361e-02  9.429036e-02  9.744577e-02
## ASV13793    -2.086138e-02 -2.128854e-02 -2.171638e-02 -2.214476e-02
## ASV14482     1.602157e-03  1.680600e-03  1.762877e-03  1.849044e-03
## ASV15483     1.343987e-02  1.387548e-02  1.432150e-02  1.477808e-02
## ASV2062      5.126343e-02  5.275729e-02  5.428110e-02  5.583491e-02
## ASV2132      5.059428e-02  5.219519e-02  5.382814e-02  5.549294e-02
## ASV2413      3.606718e-02  3.707289e-02  3.810034e-02  3.914997e-02
## ASV2490      8.672173e-02  8.847101e-02  9.023028e-02  9.199933e-02
## ASV2594      2.122626e-02  2.207967e-02  2.296437e-02  2.388120e-02
## ASV2822     -5.506662e-02 -5.619943e-02 -5.733511e-02 -5.847341e-02
## ASV2863      6.055686e-02  6.201181e-02  6.348655e-02  6.498118e-02
## ASV2910      2.285018e-02  2.341916e-02  2.399760e-02  2.458567e-02
## ASV2980      2.992887e-02  3.075747e-02  3.160082e-02  3.245900e-02
## ASV3307      4.384845e-02  4.475540e-02  4.566550e-02  4.657858e-02
## ASV3474      5.377044e-02  5.568821e-02  5.765424e-02  5.966867e-02
## ASV3502      4.430565e-02  4.577245e-02  4.728016e-02  4.882971e-02
## ASV4236      3.721576e-02  3.785544e-02  3.849418e-02  3.913179e-02
## ASV4842     -3.681801e-03 -3.639312e-03 -3.588006e-03 -3.527664e-03
## ASV4894     -2.089767e-02 -2.133197e-02 -2.176805e-02 -2.220581e-02
## ASV5290      2.500420e-02  2.581978e-02  2.665704e-02  2.751650e-02
## ASV5501      1.869331e-02  1.949118e-02  2.032115e-02  2.118419e-02
## ASV5795      1.722094e-02  1.775970e-02  1.830850e-02  1.886718e-02
## ASV5987     -5.840874e-02 -5.962877e-02 -6.085444e-02 -6.208549e-02
## ASV6267     -6.584053e-02 -6.721883e-02 -6.860382e-02 -6.999520e-02
## ASV6862      2.577350e-02  2.638029e-02  2.699586e-02  2.762024e-02
## ASV7145      1.301835e-02  1.343065e-02  1.385480e-02  1.429100e-02
## ASV7673     -2.093326e-02 -2.137298e-02 -2.181496e-02 -2.225910e-02
## ASV7789      2.819823e-02  2.943652e-02  3.071872e-02  3.204574e-02
## ASV7809      5.757932e-03  6.012901e-03  6.274212e-03  6.541785e-03
## ASV8002     -2.646633e-02 -2.702552e-02 -2.758786e-02 -2.815320e-02
## ASV8205      1.718706e-02  1.775369e-02  1.833292e-02  1.892471e-02
## ASV9155     -4.972890e-03 -5.019978e-03 -5.064311e-03 -5.105789e-03
## ASV9221      1.420066e-02  1.491615e-02  1.566087e-02  1.643573e-02
## ASV9311     -4.252726e-02 -4.343251e-02 -4.434327e-02 -4.525929e-02
## ASV9557     -2.908034e-02 -2.970059e-02 -3.032466e-02 -3.095237e-02
## ASV9936     -5.867754e-02 -5.993144e-02 -6.119316e-02 -6.246233e-02
## ASV1445      5.296234e-02  5.462221e-02  5.631554e-02  5.804209e-02
## ASV4232      3.327159e-02  3.483539e-02  3.646655e-02  3.816724e-02
## ASV6479      2.154979e-02  2.262584e-02  2.374477e-02  2.490754e-02
## ASV0142     -2.574478e-02 -2.635055e-02 -2.696413e-02 -2.758557e-02
## ASV0378      2.169645e-02  2.241604e-02  2.314753e-02  2.389041e-02
## ASV1122      5.511364e-02  5.698033e-02  5.889435e-02  6.085614e-02
## ASV0123     -2.220539e-02 -2.270543e-02 -2.321037e-02 -2.372017e-02
## ASV2064      4.205922e-03  4.020081e-03  3.815862e-03  3.592711e-03
## ASV4459     -1.273434e-03 -1.367500e-03 -1.469853e-03 -1.580880e-03
## ASV0448      1.825462e-02  1.892037e-02  1.960234e-02  2.030038e-02
## ASV0397      2.634281e-02  2.709315e-02  2.785716e-02  2.863487e-02
## ASV0485      2.866063e-02  2.945413e-02  3.026153e-02  3.108278e-02
## ASV1566      4.451232e-02  4.576574e-02  4.704043e-02  4.833624e-02
## ASV1365      3.898687e-02  4.003020e-02  4.108702e-02  4.215730e-02
## ASV1065      5.859604e-02  6.035043e-02  6.213831e-02  6.395960e-02
## ASV0722     -5.604913e-03 -5.881916e-03 -6.171530e-03 -6.474191e-03
## ASV12660    -2.327876e-02 -2.378092e-02 -2.428710e-02 -2.479725e-02
## ASV0223      8.807175e-03  9.094707e-03  9.390203e-03  9.693776e-03
## ASV0229      1.687430e-02  1.750011e-02  1.814641e-02  1.881375e-02
## ASV0877     -3.980128e-03 -4.499005e-03 -5.054292e-03 -5.647544e-03
## ASV0983      2.565945e-02  2.626305e-02  2.687123e-02  2.748372e-02
## ASV0626      1.075018e-02  1.119682e-02  1.165572e-02  1.212699e-02
## ASV4146     -4.410609e-03 -4.853849e-03 -5.326549e-03 -5.829676e-03
## ASV4175     -4.338170e-02 -4.472618e-02 -4.609594e-02 -4.749072e-02
## ASV2082     -4.412455e-02 -4.619356e-02 -4.833761e-02 -5.055778e-02
## ASV2272      2.218546e-02  2.297448e-02  2.378657e-02  2.462217e-02
## ASV2245     -3.195198e-02 -3.295474e-02 -3.397641e-02 -3.501680e-02
## ASV0590     -4.564018e-02 -4.780774e-02 -5.005647e-02 -5.238788e-02
## ASV0217      1.379099e-02  1.447716e-02  1.518860e-02  1.592590e-02
## ASV0416      5.667218e-03  5.467152e-03  5.248642e-03  5.011288e-03
## ASV1056      3.369936e-02  3.480383e-02  3.593051e-02  3.707918e-02
## ASV7777     -4.571586e-02 -4.745965e-02 -4.927031e-02 -5.115074e-02
## ASV0455      6.186264e-03  6.322902e-03  6.458130e-03  6.591630e-03
## ASV0604      2.436584e-02  2.523480e-02  2.612597e-02  2.703946e-02
## ASV6100     -3.487881e-02 -3.626416e-02 -3.770109e-02 -3.919131e-02
## ASV11359    -5.835643e-02 -6.001086e-02 -6.168701e-02 -6.338415e-02
## ASV6604      1.001190e-02  1.031753e-02  1.062524e-02  1.093447e-02
## ASV5004     -2.226877e-02 -2.304031e-02 -2.383453e-02 -2.465181e-02
## ASV1483     -8.112866e-03 -8.322163e-03 -8.532445e-03 -8.743429e-03
## ASV9773     -3.077635e-02 -3.188918e-02 -3.303650e-02 -3.421910e-02
## ASV4059      9.483002e-03  9.915363e-03  1.035472e-02  1.080022e-02
## ASV1193      3.051865e-02  3.142869e-02  3.235654e-02  3.330214e-02
## ASV4610      4.088446e-03  4.280743e-03  4.472137e-03  4.662019e-03
## ASV0742      5.936609e-03  6.232915e-03  6.534877e-03  6.842224e-03
## ASV1502     -7.712510e-03 -8.038891e-03 -8.371931e-03 -8.711357e-03
## ASV0195     -3.055036e-03 -3.224523e-03 -3.400336e-03 -3.582610e-03
## ASV1213      1.138577e-02  1.150006e-02  1.160796e-02  1.170914e-02
## ASV1648     -3.184939e-02 -3.314000e-02 -3.447892e-02 -3.586753e-02
## ASV6984     -3.056563e-02 -3.182543e-02 -3.313321e-02 -3.449040e-02
## ASV0396      3.073518e-04  2.163420e-04  1.096584e-04 -1.403081e-05
## ASV4297      2.027506e-02  2.067940e-02  2.108867e-02  2.150321e-02
## ASV2622      3.965803e-02  4.066675e-02  4.169082e-02  4.273027e-02
## ASV3512      4.008645e-02  4.197568e-02  4.394247e-02  4.598910e-02
## ASV2411      4.448851e-02  4.603725e-02  4.761965e-02  4.923516e-02
## ASV2291     -3.859994e-02 -4.031981e-02 -4.209533e-02 -4.392710e-02
## ASV0807      4.261784e-02  4.378842e-02  4.497908e-02  4.619014e-02
## ASV1292      4.915846e-03  5.003461e-03  5.096654e-03  5.196063e-03
## ASV1035      3.384990e-02  3.478450e-02  3.574045e-02  3.671829e-02
## ASV0070      5.944752e-03  6.269497e-03  6.607182e-03  6.958038e-03
## ASV0255     -1.036983e-03 -1.269255e-03 -1.519356e-03 -1.788069e-03
## ASV0057     -5.237933e-03 -5.241204e-03 -5.238251e-03 -5.228899e-03
## ASV0077     -2.428716e-05 -1.389986e-05 -6.993569e-06 -4.120710e-06
## ASV0625      1.595993e-02  1.626816e-02  1.657724e-02  1.688712e-02
## ASV2464      1.131732e-01  1.156038e-01  1.180528e-01  1.205197e-01
## ASV1315      5.995871e-02  6.210872e-02  6.431091e-02  6.656501e-02
## ASV2673      5.270246e-02  5.466630e-02  5.668504e-02  5.875913e-02
## ASV2161      2.332373e-02  2.426047e-02  2.522839e-02  2.622802e-02
## ASV0337     -1.056292e-02 -1.092753e-02 -1.130206e-02 -1.168660e-02
## ASV7680     -7.078268e-02 -7.317857e-02 -7.563033e-02 -7.813777e-02
## ASV0611      4.159870e-02  4.312855e-02  4.470543e-02  4.633036e-02
## ASV3118     -4.915906e-02 -5.097670e-02 -5.284338e-02 -5.475949e-02
## ASV1284     -2.590022e-02 -2.784446e-02 -2.989311e-02 -3.204982e-02
## ASV0889      2.360019e-02  2.438491e-02  2.519615e-02  2.603494e-02
## ASV4649     -1.381174e-02 -1.427507e-02 -1.475057e-02 -1.523840e-02
## ASV1108     -4.181850e-02 -4.348922e-02 -4.521076e-02 -4.698373e-02
## ASV0738      3.282203e-02  3.438626e-02  3.601540e-02  3.771156e-02
## ASV0473     -5.355460e-03 -5.435468e-03 -5.503179e-03 -5.557147e-03
## ASV0598     -2.055761e-02 -2.157544e-02 -2.263380e-02 -2.373355e-02
## ASV0429      1.161193e-02  1.177632e-02  1.193683e-02  1.209340e-02
## ASV1549      4.860208e-02  5.035248e-02  5.214334e-02  5.397403e-02
## ASV1203      2.298933e-02  2.355394e-02  2.412329e-02  2.469711e-02
## ASV4532      9.343319e-04  1.032954e-03  1.141447e-03  1.260461e-03
## ASV0274      6.237677e-03  6.376642e-03  6.510891e-03  6.639745e-03
## ASV0163     -1.544669e-02 -1.586827e-02 -1.630180e-02 -1.674779e-02
## ASV1298      3.792694e-03  4.089180e-03  4.407641e-03  4.749198e-03
## ASV9424     -6.128596e-02 -6.366376e-02 -6.612148e-02 -6.866101e-02
## ASV0412      3.916696e-02  4.017400e-02  4.119635e-02  4.223416e-02
## ASV0284     -7.049791e-04 -1.048403e-03 -1.417573e-03 -1.813646e-03
## ASV0620     -2.066052e-02 -2.155628e-02 -2.248228e-02 -2.343904e-02
## ASV0153     -6.303210e-02 -6.524917e-02 -6.751703e-02 -6.983530e-02
## ASV0498      1.602942e-02  1.639243e-02  1.675176e-02  1.710672e-02
## ASV0097      1.277079e-02  1.322987e-02  1.369946e-02  1.417938e-02
## ASV0104     -5.693834e-02 -5.839361e-02 -5.986408e-02 -6.134922e-02
## ASV1282      9.944201e-03  9.813402e-03  9.654733e-03  9.466869e-03
## ASV3883     -2.818047e-02 -2.917174e-02 -3.018035e-02 -3.120544e-02
## ASV0801      1.169962e-02  1.220034e-02  1.272292e-02  1.326822e-02
## ASV1611     -5.574344e-02 -5.779814e-02 -5.990975e-02 -6.207874e-02
## ASV0227     -1.810167e-02 -1.891685e-02 -1.976139e-02 -2.063596e-02
## ASV0833      1.528985e-02  1.577001e-02  1.626050e-02  1.676139e-02
## ASV0718      6.937083e-02  7.160126e-02  7.388060e-02  7.620889e-02
## ASV1139     -5.692856e-03 -6.213069e-03 -6.757790e-03 -7.327362e-03
## ASV0766     -1.422478e-02 -1.473716e-02 -1.526015e-02 -1.579357e-02
## ASV2091      3.202707e-02  3.254897e-02  3.306496e-02  3.357474e-02
## ASV1238     -6.867826e-02 -7.164236e-02 -7.472571e-02 -7.793205e-02
## ASV9193     -2.014154e-02 -2.122442e-02 -2.235352e-02 -2.352990e-02
## ASV0290      2.635254e-03  2.736926e-03  2.847598e-03  2.967799e-03
## ASV0231      1.384176e-02  1.408818e-02  1.432907e-02  1.456384e-02
## ASV0185      2.445834e-02  2.559281e-02  2.677111e-02  2.799434e-02
## ASV2330      1.258120e-02  1.283089e-02  1.308489e-02  1.334341e-02
## ASV3119     -2.086129e-02 -2.179854e-02 -2.276997e-02 -2.377630e-02
## ASV2368     -3.990871e-02 -4.167426e-02 -4.350837e-02 -4.541278e-02
## ASV0122     -1.037762e-02 -1.066945e-02 -1.096725e-02 -1.127114e-02
## ASV1044      4.106985e-02  4.265593e-02  4.429331e-02  4.598309e-02
## ASV0160     -8.244557e-03 -8.465843e-03 -8.695256e-03 -8.933274e-03
## ASV0326      2.682286e-03  2.711426e-03  2.736725e-03  2.757860e-03
## ASV1388      5.312378e-02  5.451069e-02  5.591579e-02  5.733888e-02
## ASV0792      3.224775e-02  3.292488e-02  3.360502e-02  3.428808e-02
## ASV0036     -1.799952e-02 -1.857682e-02 -1.916248e-02 -1.975600e-02
## ASV2125      3.970288e-02  4.074605e-02  4.179978e-02  4.286348e-02
## ASV1075     -1.893951e-03 -2.018039e-03 -2.149266e-03 -2.287890e-03
## ASV0390      3.590104e-02  3.741645e-02  3.898733e-02  4.061499e-02
## ASV3790     -3.913778e-02 -4.050247e-02 -4.190370e-02 -4.334189e-02
## ASV1535     -1.792427e-02 -1.864092e-02 -1.937668e-02 -2.013150e-02
## ASV0263      4.209631e-02  4.340513e-02  4.474093e-02  4.610369e-02
## ASV0675      7.605198e-02  7.874814e-02  8.151527e-02  8.435391e-02
## ASV3348      7.636591e-03  7.906321e-03  8.180750e-03  8.459594e-03
## ASV0058     -1.511361e-02 -1.548380e-02 -1.585714e-02 -1.623345e-02
## ASV4142      1.767530e-02  1.807977e-02  1.849080e-02  1.890863e-02
## ASV0059     -1.138925e-02 -1.165014e-02 -1.191290e-02 -1.217749e-02
## ASV0013     -2.598186e-02 -2.677188e-02 -2.757844e-02 -2.840167e-02
## ASV0033     -1.566533e-02 -1.618273e-02 -1.670946e-02 -1.724526e-02
## ASV4354     -1.778892e-02 -1.841360e-02 -1.905374e-02 -1.970927e-02
## ASV0022     -1.345780e-02 -1.391458e-02 -1.438030e-02 -1.485472e-02
## ASV0134     -1.785618e-02 -1.868223e-02 -1.954419e-02 -2.044340e-02
## ASV0415      3.096011e-03  3.200279e-03  3.306456e-03  3.414564e-03
## ASV10103    -7.233609e-02 -7.488153e-02 -7.748993e-02 -8.016130e-02
## ASV1613      2.806295e-02  2.847621e-02  2.887623e-02  2.926222e-02
## ASV0135     -2.341770e-03 -2.337428e-03 -2.329920e-03 -2.319148e-03
## ASV0469     -5.027287e-02 -5.179121e-02 -5.334630e-02 -5.493882e-02
## ASV0471      3.498105e-02  3.616432e-02  3.738438e-02  3.864245e-02
## ASV0451     -1.422466e-02 -1.483323e-02 -1.545913e-02 -1.610241e-02
## ASV0747      1.977617e-02  2.033745e-02  2.090527e-02  2.147928e-02
## ASV1314     -3.032729e-02 -3.160454e-02 -3.292746e-02 -3.429711e-02
## ASV0425     -4.817283e-02 -4.924138e-02 -5.032060e-02 -5.141043e-02
## ASV0559     -2.088195e-02 -2.174238e-02 -2.263552e-02 -2.356212e-02
## ASV0148      3.837857e-03  4.186061e-03  4.554164e-03  4.942918e-03
## ASV0129      1.858478e-02  1.956880e-02  2.059343e-02  2.165956e-02
## ASV1072     -5.779053e-04 -7.347292e-04 -9.003424e-04 -1.074827e-03
## ASV2390      1.524124e-02  1.519460e-02  1.512646e-02  1.503630e-02
## ASV0548      2.162557e-02  2.222755e-02  2.283926e-02  2.346070e-02
## ASV0168     -1.009624e-02 -1.037259e-02 -1.065416e-02 -1.094103e-02
## ASV0066     -1.054968e-02 -1.075619e-02 -1.095936e-02 -1.115873e-02
## ASV0468     -8.395206e-03 -8.713375e-03 -9.042833e-03 -9.383925e-03
## ASV0172      4.190616e-04  5.573467e-04  7.047249e-04  8.614914e-04
## ASV0236      1.503576e-02  1.586616e-02  1.672744e-02  1.761986e-02
## ASV0250      3.678962e-02  3.846590e-02  4.020744e-02  4.201597e-02
## ASV0338      9.568186e-03  9.795598e-03  1.002082e-02  1.024331e-02
## ASV0450     -5.645365e-03 -5.928384e-03 -6.222126e-03 -6.526693e-03
## ASV0377      1.317357e-02  1.343242e-02  1.368694e-02  1.393652e-02
## ASV1022      1.774548e-03  1.951689e-03  2.141646e-03  2.345072e-03
## ASV6174     -2.050134e-03 -2.086512e-03 -2.114864e-03 -2.134065e-03
## ASV0786     -6.864042e-03 -7.108065e-03 -7.353299e-03 -7.599167e-03
## ASV0053     -1.869236e-02 -1.926010e-02 -1.983897e-02 -2.042900e-02
## ASV0697     -9.186931e-03 -9.476417e-03 -9.776914e-03 -1.008912e-02
## ASV0785      2.009125e-02  2.065092e-02  2.122326e-02  2.180878e-02
## ASV1967     -2.000083e-02 -2.054845e-02 -2.110407e-02 -2.166747e-02
## ASV0385      9.282445e-03  9.518745e-03  9.752640e-03  9.983505e-03
## ASV0295      7.105542e-03  7.487189e-03  7.885080e-03  8.299633e-03
## ASV0072     -1.189199e-02 -1.205805e-02 -1.221728e-02 -1.236928e-02
## ASV0157      6.985728e-03  7.491837e-03  8.024649e-03  8.585059e-03
## ASV0501      3.972246e-02  4.082528e-02  4.194014e-02  4.306649e-02
## ASV10729    -5.710657e-02 -5.903518e-02 -6.101114e-02 -6.303484e-02
## ASV1470      1.027449e-02  1.017020e-02  1.004204e-02  9.888901e-03
## ASV0050     -3.606534e-02 -3.695991e-02 -3.786240e-02 -3.877242e-02
## ASV0411     -1.363698e-02 -1.420511e-02 -1.479601e-02 -1.541058e-02
## ASV0549      1.846578e-02  1.908288e-02  1.971328e-02  2.035686e-02
## ASV0184      6.082975e-03  6.340556e-03  6.610008e-03  6.891913e-03
## ASV0705      6.220080e-03  6.262068e-03  6.295258e-03  6.319008e-03
## ASV1715      2.206390e-02  2.273041e-02  2.340968e-02  2.410171e-02
## ASV0603      6.688979e-03  7.047205e-03  7.423332e-03  7.817978e-03
## ASV0826      3.477231e-02  3.582227e-02  3.689599e-02  3.799382e-02
## ASV0034     -8.559026e-03 -8.734242e-03 -8.909379e-03 -9.084353e-03
## ASV0838     -1.684323e-02 -1.827037e-02 -1.978483e-02 -2.139012e-02
## ASV0614     -9.365537e-03 -9.642753e-03 -9.926146e-03 -1.021585e-02
## ASV0014     -2.492371e-02 -2.562271e-02 -2.633241e-02 -2.705264e-02
## ASV0585     -8.612767e-03 -9.071247e-03 -9.540392e-03 -1.001967e-02
## ASV0016     -2.612392e-02 -2.686089e-02 -2.760953e-02 -2.836970e-02
## ASV5394     -2.131281e-02 -2.189664e-02 -2.248214e-02 -2.306813e-02
## ASV0666      3.231981e-02  3.301945e-02  3.372425e-02  3.443422e-02
## ASV2085     -1.066367e-02 -1.153062e-02 -1.244216e-02 -1.339977e-02
## ASV0003     -1.779456e-02 -1.830034e-02 -1.881466e-02 -1.933749e-02
## ASV0346      1.162822e-02  1.197661e-02  1.232876e-02  1.268438e-02
## ASV0267      2.500303e-03  2.538290e-03  2.567127e-03  2.585679e-03
## ASV0353      1.939974e-02  2.009077e-02  2.079936e-02  2.152552e-02
## ASV2419      3.498573e-02  3.583312e-02  3.668139e-02  3.752923e-02
## ASV0447      2.849425e-02  2.952420e-02  3.058389e-02  3.167391e-02
## ASV0654      3.058384e-02  3.141783e-02  3.226339e-02  3.312037e-02
## ASV0151      9.794271e-03  1.021693e-02  1.065195e-02  1.109929e-02
## ASV0065     -1.108921e-02 -1.138676e-02 -1.168914e-02 -1.199636e-02
## ASV0527      2.889826e-02  2.969005e-02  3.049163e-02  3.130253e-02
## ASV4055     -1.253476e-02 -1.327044e-02 -1.404873e-02 -1.487186e-02
## ASV0166     -1.117663e-02 -1.142715e-02 -1.168141e-02 -1.193965e-02
## ASV0417     -2.069298e-03 -2.040127e-03 -2.008438e-03 -1.974450e-03
## ASV0078     -5.829603e-03 -5.878620e-03 -5.920493e-03 -5.954720e-03
## ASV0322      6.391603e-03  6.869731e-03  7.372699e-03  7.901164e-03
## ASV0156     -2.706113e-02 -2.806925e-02 -2.911056e-02 -3.018601e-02
## ASV0648     -5.751787e-02 -5.945906e-02 -6.144174e-02 -6.346523e-02
## ASV0407     -6.016950e-03 -6.285698e-03 -6.565085e-03 -6.855411e-03
## ASV2030     -1.180241e-02 -1.237097e-02 -1.296401e-02 -1.358211e-02
## ASV0300      7.674156e-03  7.934948e-03  8.200701e-03  8.471278e-03
## ASV1150      2.312178e-03  2.376211e-03  2.438903e-03  2.499954e-03
## ASV0958      2.791537e-02  2.908624e-02  3.029849e-02  3.155307e-02
## ASV0216     -2.086544e-02 -2.167113e-02 -2.250842e-02 -2.337840e-02
## ASV0446      3.394443e-02  3.503113e-02  3.613886e-02  3.726739e-02
## ASV0367     -2.111580e-02 -2.179380e-02 -2.248615e-02 -2.319277e-02
## ASV0200     -1.151170e-02 -1.181923e-02 -1.212776e-02 -1.243679e-02
## ASV0334     -1.861196e-03 -1.907361e-03 -1.960007e-03 -2.019810e-03
## ASV1311      8.244798e-04  6.594804e-04  4.815271e-04  2.901338e-04
## ASV0458      1.984135e-03  1.838872e-03  1.682771e-03  1.515618e-03
## ASV1371      2.133127e-03  2.165244e-03  2.194504e-03  2.220680e-03
## ASV0418      1.795461e-02  1.833886e-02  1.872596e-02  1.911602e-02
## ASV0004      2.349394e-03  2.391145e-03  2.432662e-03  2.473914e-03
## ASV1943      2.080599e-02  2.063496e-02  2.044195e-02  2.022701e-02
## ASV1495     -1.910062e-02 -2.006994e-02 -2.107671e-02 -2.212152e-02
## ASV0901     -3.012962e-02 -3.134996e-02 -3.261433e-02 -3.392390e-02
## ASV0628      3.775795e-03  3.659799e-03  3.528597e-03  3.381412e-03
## ASV0400      3.421936e-03  3.368955e-03  3.303329e-03  3.224218e-03
## ASV0116     -8.375160e-03 -8.692557e-03 -9.019902e-03 -9.357391e-03
## ASV0788      7.697766e-02  8.004004e-02  8.321238e-02  8.649822e-02
## ASV0117      6.463938e-03  6.717317e-03  6.978604e-03  7.247989e-03
## ASV3137     -6.153760e-04 -5.921790e-04 -5.643879e-04 -5.316002e-04
## ASV0001      2.363253e-03  2.405595e-03  2.448496e-03  2.492043e-03
## ASV1651      7.951132e-03  8.144832e-03  8.343674e-03  8.548068e-03
## ASV1692      6.108930e-02  6.340414e-02  6.579564e-02  6.826604e-02
## ASV0660      2.851137e-03  2.541585e-03  2.207612e-03  1.848647e-03
## ASV0508     -7.314098e-05 -1.160550e-04 -1.634773e-04 -2.157501e-04
## ASV1660     -1.512618e-02 -1.565215e-02 -1.618628e-02 -1.672798e-02
## ASV0233      1.568874e-02  1.620313e-02  1.673063e-02  1.727149e-02
## ASV1343     -3.461619e-02 -3.593531e-02 -3.729763e-02 -3.870419e-02
## ASV0209      7.417653e-03  7.481340e-03  7.537877e-03  7.586823e-03
## ASV0193     -8.845487e-03 -8.909319e-03 -8.963515e-03 -9.007549e-03
## ASV0357      1.580128e-02  1.661657e-02  1.746775e-02  1.835583e-02
## ASV0198      1.106685e-02  1.142012e-02  1.178335e-02  1.215678e-02
## ASV0007      1.649203e-03  1.664870e-03  1.680413e-03  1.695916e-03
## ASV1772      6.092087e-03  6.860372e-03  7.692709e-03  8.593149e-03
## ASV0009      1.020919e-03  1.019969e-03  1.018896e-03  1.017821e-03
## ASV0006     -4.746601e-03 -4.924877e-03 -5.107808e-03 -5.295400e-03
## ASV0011     -1.315351e-02 -1.361122e-02 -1.408110e-02 -1.456328e-02
## ASV0015      5.258231e-04  5.000002e-04  4.717426e-04  4.409605e-04
## ASV0017      7.972953e-04  7.836808e-04  7.682483e-04  7.509342e-04
## ASV0235     -1.282011e-02 -1.329907e-02 -1.379383e-02 -1.430485e-02
## ASV0382      6.077404e-03  6.083328e-03  6.073582e-03  6.046993e-03
## ASV2357      4.042621e-02  4.186377e-02  4.333890e-02  4.485159e-02
## ASV0567     -1.033936e-02 -1.082329e-02 -1.132853e-02 -1.185578e-02
## ASV0165      6.078717e-03  6.267339e-03  6.459741e-03  6.655951e-03
## ASV0005      7.237120e-03  7.421427e-03  7.607172e-03  7.794231e-03
## ASV0384      4.030813e-03  4.321034e-03  4.627560e-03  4.951057e-03
## ASV0002      1.230938e-03  1.265291e-03  1.300248e-03  1.335797e-03
## ASV3017      2.732965e-02  2.778651e-02  2.823796e-02  2.868369e-02
## ASV0091     -1.793018e-03 -1.901473e-03 -2.016946e-03 -2.139826e-03
## ASV0186     -1.482779e-02 -1.518820e-02 -1.554926e-02 -1.591062e-02
## ASV0370      7.492517e-03  7.717941e-03  7.950320e-03  8.189999e-03
## ASV0018      9.716334e-03  9.981931e-03  1.025102e-02  1.052350e-02
## ASV1377      7.503835e-02  7.664415e-02  7.825868e-02  7.988186e-02
## ASV0019      1.039189e-02  1.068443e-02  1.098146e-02  1.128292e-02
## ASV0023     -8.022246e-03 -8.277761e-03 -8.537638e-03 -8.801754e-03
## ASV2194      1.637347e-02  1.704839e-02  1.774659e-02  1.846855e-02
## ASV1155      3.716015e-02  3.831044e-02  3.949506e-02  4.071531e-02
## ASV0510     -5.941924e-03 -6.072664e-03 -6.207662e-03 -6.347024e-03
## ASV2371     -2.009793e-02 -2.056744e-02 -2.103972e-02 -2.151454e-02
## ASV0024     -9.878935e-03 -1.019574e-02 -1.051837e-02 -1.084673e-02
## ASV2452      1.096897e-02  1.094596e-02  1.090968e-02  1.085990e-02
## ASV2332     -6.684492e-02 -6.882464e-02 -7.084715e-02 -7.291273e-02
## ASV2591      2.966220e-02  3.059687e-02  3.154356e-02  3.250166e-02
## ASV0521      2.125738e-02  2.202241e-02  2.280933e-02  2.361851e-02
## ASV5542      1.876071e-02  1.938568e-02  2.002646e-02  2.068326e-02
## ASV0336     -6.540531e-03 -6.873432e-03 -7.222224e-03 -7.587693e-03
## ASV10102     3.420301e-02  3.527199e-02  3.636079e-02  3.746922e-02
## ASV16823    -3.049305e-02 -3.114760e-02 -3.180839e-02 -3.247545e-02
## ASV3104      1.577609e-01  1.611463e-01  1.645641e-01  1.680142e-01
## ASV0781      3.456121e-02  3.570833e-02  3.688786e-02  3.810049e-02
## ASV10899     4.127225e-02  4.310569e-02  4.500528e-02  4.697243e-02
## ASV11222    -5.365964e-02 -5.481079e-02 -5.597290e-02 -5.714601e-02
## ASV11327    -4.817253e-02 -4.920576e-02 -5.024883e-02 -5.130177e-02
## ASV12458    -5.365037e-02 -5.480090e-02 -5.596239e-02 -5.713488e-02
## ASV1636      3.749649e-02  3.846755e-02  3.945461e-02  4.045788e-02
## ASV1890     -1.875079e-02 -1.911312e-02 -1.948606e-02 -1.987053e-02
## ASV2898      5.091374e-02  5.226454e-02  5.364099e-02  5.504365e-02
## ASV8328      3.991716e-02  4.193278e-02  4.402220e-02  4.618624e-02
## ASV0709     -6.087117e-02 -6.247598e-02 -6.410245e-02 -6.575023e-02
## ASV0856      7.564368e-02  7.828805e-02  8.099425e-02  8.376204e-02
## ASV0909      4.261154e-02  4.452117e-02  4.649484e-02  4.853350e-02
## ASV0937     -5.528808e-02 -5.751295e-02 -5.981472e-02 -6.219486e-02
## ASV11390    -7.655504e-02 -7.819622e-02 -7.985304e-02 -8.152558e-02
## ASV11966     4.006162e-02  4.145885e-02  4.288615e-02  4.434320e-02
## ASV12990     1.511106e-02  1.548150e-02  1.585758e-02  1.623920e-02
## ASV14797     2.135985e-02  2.186705e-02  2.238219e-02  2.290535e-02
## ASV14904    -1.098434e-01 -1.121979e-01 -1.145749e-01 -1.169744e-01
## ASV15304     2.962997e-02  3.071532e-02  3.182501e-02  3.295877e-02
## ASV16696    -3.795137e-02 -3.876489e-02 -3.958619e-02 -4.041531e-02
## ASV1690      1.168196e-01  1.203543e-01  1.239377e-01  1.275681e-01
## ASV2029      6.246428e-02  6.427809e-02  6.612761e-02  6.801296e-02
## ASV2834      9.181134e-02  9.459167e-02  9.742007e-02  1.002960e-01
## ASV4003      1.247349e-01  1.304699e-01  1.364478e-01  1.426773e-01
## ASV4064      4.680239e-02  4.837778e-02  4.999476e-02  5.165415e-02
## ASV4294      4.808170e-02  5.020257e-02  5.239989e-02  5.467526e-02
## ASV4609      2.243746e-02  2.318619e-02  2.395604e-02  2.474728e-02
## ASV6283     -3.547410e-02 -3.623454e-02 -3.700227e-02 -3.777734e-02
## ASV6491     -5.084480e-02 -5.193485e-02 -5.303539e-02 -5.414645e-02
## ASV7453      5.546602e-02  5.745444e-02  5.948853e-02  6.156803e-02
## ASV7959      3.339702e-02  3.495247e-02  3.656841e-02  3.824651e-02
## ASV8219      4.394111e-01  4.488339e-01  4.583477e-01  4.679529e-01
## ASV8547     -4.552233e-02 -4.649870e-02 -4.748450e-02 -4.847980e-02
## ASV9319      4.209243e-02  4.376253e-02  4.549036e-02  4.727742e-02
## ASV9382     -8.907231e-02 -9.098315e-02 -9.291251e-02 -9.486050e-02
## ASV11516    -5.949471e-02 -6.077131e-02 -6.206031e-02 -6.336179e-02
## ASV14377    -4.295975e-02 -4.388177e-02 -4.481276e-02 -4.575279e-02
## ASV1867      6.143498e-02  6.364078e-02  6.591302e-02  6.825323e-02
## ASV1895      8.155745e-03  7.938024e-03  7.696064e-03  7.429274e-03
## ASV3168      1.920732e-02  1.949548e-02  1.977887e-02  2.005724e-02
## ASV4449      1.879124e-01  1.943259e-01  2.009247e-01  2.077132e-01
## ASV6596      6.637293e-02  6.923306e-02  7.219119e-02  7.524872e-02
## ASV7492      1.403666e-02  1.489441e-02  1.578341e-02  1.670371e-02
## ASV9854     -8.501317e-03 -8.665599e-03 -8.830722e-03 -8.996743e-03
## ASV6296      7.209724e-01  7.364572e-01  7.520939e-01  7.678835e-01
## ASV4201      3.243623e-02  3.420468e-02  3.605238e-02  3.798192e-02
## ASV0552      3.872091e-02  3.990114e-02  4.109922e-02  4.231439e-02
## ASV3671     -2.912961e-02 -3.039993e-02 -3.172501e-02 -3.310663e-02
## ASV3529      5.940985e-03  6.243718e-03  6.549999e-03  6.859296e-03
## ASV1060      1.585027e-02  1.658539e-02  1.735225e-02  1.815198e-02
## ASV0239     -6.202442e-03 -6.249046e-03 -6.290224e-03 -6.325615e-03
## ASV5711     -5.105576e-02 -5.250719e-02 -5.398348e-02 -5.548432e-02
## ASV4152     -8.469683e-02 -8.725265e-02 -8.985053e-02 -9.248954e-02
## ASV1461      2.162076e-02  2.188515e-02  2.214162e-02  2.238979e-02
## ASV2877      1.124123e-02  1.131311e-02  1.137268e-02  1.141923e-02
## ASV0012      3.848693e-03  3.973109e-03  4.100422e-03  4.230647e-03
## ASV9823     -6.006522e-03 -6.535664e-03 -7.092999e-03 -7.679227e-03
## ASV0008      3.979886e-03  4.107514e-03  4.238141e-03  4.371786e-03
## ASV7832     -5.576419e-02 -5.767878e-02 -5.964119e-02 -6.165176e-02
## ASV1915     -7.444112e-03 -7.769280e-03 -8.107684e-03 -8.459725e-03
## ASV0055     -8.359329e-03 -8.731678e-03 -9.117934e-03 -9.518461e-03
## ASV0032      3.132730e-04  3.148639e-04  3.188822e-04  3.256844e-04
## ASV2977     -6.731970e-02 -6.925755e-02 -7.122267e-02 -7.321429e-02
## ASV0466      2.753918e-02  2.776483e-02  2.797093e-02  2.815670e-02
## ASV3866      4.921224e-02  5.113368e-02  5.312008e-02  5.517296e-02
## ASV0040      1.476756e-02  1.524699e-02  1.573687e-02  1.623718e-02
## ASV0496     -1.459888e-02 -1.527878e-02 -1.597869e-02 -1.669849e-02
## ASV0052      1.278228e-02  1.322891e-02  1.368893e-02  1.416271e-02
## ASV3828     -2.478823e-02 -2.529194e-02 -2.579905e-02 -2.630956e-02
## ASV1930      1.279185e-02  1.299656e-02  1.319845e-02  1.339733e-02
## ASV2126      3.204858e-02  3.303370e-02  3.404270e-02  3.507598e-02
## ASV0793      5.088465e-02  5.269940e-02  5.456845e-02  5.649327e-02
## ASV0299     -5.234164e-03 -5.620256e-03 -6.030237e-03 -6.465080e-03
## ASV0208      3.529710e-02  3.657561e-02  3.789412e-02  3.925360e-02
## ASV0511     -6.478252e-03 -6.613629e-03 -6.753841e-03 -6.899212e-03
## ASV1123     -1.996076e-02 -2.012582e-02 -2.026959e-02 -2.039040e-02
## ASV0099      3.763797e-03  3.967936e-03  4.180993e-03  4.403180e-03
## ASV0752     -3.093767e-02 -3.215450e-02 -3.341120e-02 -3.470857e-02
## ASV0883      3.829342e-02  3.958237e-02  4.089658e-02  4.223560e-02
## ASV0683      4.969107e-02  5.148235e-02  5.332178e-02  5.520975e-02
## ASV4117     -7.282051e-02 -7.544016e-02 -7.813638e-02 -8.091057e-02
## ASV2172     -2.359264e-03 -2.633953e-03 -2.926015e-03 -3.236111e-03
## ASV0330     -1.439853e-02 -1.494858e-02 -1.551749e-02 -1.610579e-02
## ASV0728      5.557389e-02  5.726699e-02  5.899951e-02  6.077226e-02
## ASV0499      2.035741e-02  2.112089e-02  2.190649e-02  2.271445e-02
## ASV0120     -2.365839e-02 -2.427473e-02 -2.489480e-02 -2.551790e-02
## ASV1446     -1.891304e-03 -2.545012e-03 -3.243633e-03 -3.988821e-03
## ASV17171    -5.455033e-02 -5.649943e-02 -5.850596e-02 -6.057069e-02
## ASV0533      6.087033e-03  6.325731e-03  6.570889e-03  6.822510e-03
## ASV2495     -2.619590e-02 -2.732800e-02 -2.849374e-02 -2.969313e-02
## ASV5582      4.878983e-03  4.573076e-03  4.235795e-03  3.865376e-03
## ASV1488      3.830478e-03  3.763562e-03  3.683862e-03  3.590731e-03
## ASV0682      1.477139e-02  1.529762e-02  1.583615e-02  1.638685e-02
## ASV0068     -1.822709e-02 -1.868795e-02 -1.914984e-02 -1.961219e-02
## ASV1987     -6.791096e-02 -7.047031e-02 -7.310182e-02 -7.580614e-02
## ASV0035     -1.518545e-02 -1.606151e-02 -1.698042e-02 -1.794362e-02
## ASV7192     -2.410369e-02 -2.465595e-02 -2.520830e-02 -2.576016e-02
## ASV0873     -1.024066e-01 -1.071412e-01 -1.120069e-01 -1.170035e-01
## ASV4749     -2.558917e-02 -2.697673e-02 -2.841836e-02 -2.991503e-02
## ASV2174      5.343384e-03  5.137168e-03  4.912106e-03  4.667831e-03
## ASV1476     -3.100654e-02 -3.223695e-02 -3.350656e-02 -3.481613e-02
## ASV0740     -8.386097e-02 -8.718742e-02 -9.062690e-02 -9.418211e-02
## ASV0170     -1.298099e-02 -1.342742e-02 -1.388648e-02 -1.435841e-02
## ASV2466     -6.147797e-02 -6.362837e-02 -6.583667e-02 -6.810335e-02
## ASV1709      2.505490e-02  2.631391e-02  2.764297e-02  2.904560e-02
## ASV6170     -1.051117e-01 -1.088747e-01 -1.127367e-01 -1.166978e-01
## ASV3673      5.517644e-02  5.719807e-02  5.927269e-02  6.140032e-02
## ASV1745     -1.810878e-02 -1.884779e-02 -1.960981e-02 -2.039509e-02
##                                                                    
## (Intercept)  3.148073e-01  3.233631e-01  3.320310e-01  3.408080e-01
## ASV1236      4.853896e-02  4.970392e-02  5.088351e-02  5.207756e-02
## ASV0421      1.724089e-02  1.786048e-02  1.849105e-02  1.913231e-02
## ASV0691     -1.773816e-02 -1.782048e-02 -1.789489e-02 -1.796125e-02
## ASV0899      3.857922e-02  3.938411e-02  4.019710e-02  4.101845e-02
## ASV1004      9.504767e-02  9.721606e-02  9.940662e-02  1.016191e-01
## ASV1041     -2.843423e-02 -2.862922e-02 -2.880100e-02 -2.894876e-02
## ASV1058      6.088586e-02  6.236239e-02  6.385861e-02  6.537437e-02
## ASV12542     2.085281e-02  2.137649e-02  2.191221e-02  2.246028e-02
## ASV1294      5.856929e-02  6.009982e-02  6.166019e-02  6.325089e-02
## ASV13113     4.148370e-02  4.319188e-02  4.495760e-02  4.678192e-02
## ASV1318      5.588647e-02  5.724438e-02  5.862433e-02  6.002669e-02
## ASV2269     -8.581354e-02 -8.740183e-02 -8.898748e-02 -9.056943e-02
## ASV2542      7.945753e-02  8.229369e-02  8.520872e-02  8.820358e-02
## ASV2660     -3.438808e-02 -3.509619e-02 -3.580967e-02 -3.652839e-02
## ASV2737      1.004804e-02  1.028190e-02  1.052116e-02  1.076603e-02
## ASV2840      3.270162e-02  3.301623e-02  3.331881e-02  3.360923e-02
## ASV3053      2.310493e-01  2.361619e-01  2.413333e-01  2.465624e-01
## ASV3077      1.638342e-02  1.681435e-02  1.725432e-02  1.770351e-02
## ASV3134      5.983760e-02  6.220301e-02  6.464433e-02  6.716283e-02
## ASV3140      5.303378e-02  5.451574e-02  5.601972e-02  5.754522e-02
## ASV3579      3.364599e-02  3.490042e-02  3.618333e-02  3.749441e-02
## ASV6119     -2.351418e-02 -2.395393e-02 -2.439287e-02 -2.483059e-02
## ASV7557     -4.780399e-02 -4.869930e-02 -4.959277e-02 -5.048350e-02
## ASV8422      1.303193e-02  1.339542e-02  1.376906e-02  1.415326e-02
## ASV1086     -1.733342e-03 -1.802874e-03 -1.875675e-03 -1.951886e-03
## ASV1310      2.406400e-02  2.454973e-02  2.503582e-02  2.552195e-02
## ASV15750    -6.200994e-04 -5.466112e-04 -4.678338e-04 -3.835561e-04
## ASV16905    -9.844898e-03 -1.002986e-02 -1.021428e-02 -1.039797e-02
## ASV2033      7.794933e-02  8.055299e-02  8.322189e-02  8.595719e-02
## ASV2089      2.078313e-02  2.116947e-02  2.155415e-02  2.193674e-02
## ASV2127      7.512152e-02  7.689942e-02  7.869943e-02  8.052128e-02
## ASV2725      5.100821e-02  5.198835e-02  5.297297e-02  5.396201e-02
## ASV2804     -2.039589e-02 -2.077884e-02 -2.116044e-02 -2.154030e-02
## ASV3075      7.574200e-02  7.845351e-02  8.124582e-02  8.411997e-02
## ASV3327      1.059183e-01  1.093375e-01  1.128370e-01  1.164178e-01
## ASV3342      9.056057e-02  9.357156e-02  9.665842e-02  9.982196e-02
## ASV3532     -9.811759e-02 -1.016106e-01 -1.052152e-01 -1.089342e-01
## ASV3600      4.368560e-02  4.504708e-02  4.643706e-02  4.785552e-02
## ASV4013      6.346607e-02  6.500918e-02  6.656610e-02  6.813619e-02
## ASV4136      5.737664e-02  5.872288e-02  6.008663e-02  6.146776e-02
## ASV4195      2.083723e-01  2.122785e-01  2.161696e-01  2.200419e-01
## ASV4407     -8.052160e-02 -8.202976e-02 -8.353196e-02 -8.502692e-02
## ASV4717      1.081293e-02  1.107944e-02  1.135562e-02  1.164183e-02
## ASV6794      3.339706e-02  3.423897e-02  3.509908e-02  3.597770e-02
## ASV8324     -4.133916e-02 -4.211331e-02 -4.288442e-02 -4.365188e-02
## ASV8981      6.331559e-03  6.693270e-03  7.068070e-03  7.456000e-03
## ASV9859      5.011873e-02  5.251799e-02  5.501554e-02  5.761396e-02
## ASV0936      6.139694e-02  6.310983e-02  6.484666e-02  6.660706e-02
## ASV12683    -6.804069e-05 -9.538400e-06  5.524689e-05  1.265776e-04
## ASV1293      2.770980e-02  2.829818e-02  2.889124e-02  2.948898e-02
## ASV13055     4.484114e-03  4.745099e-03  5.016930e-03  5.299807e-03
## ASV17063    -2.145512e-02 -2.185578e-02 -2.225512e-02 -2.265295e-02
## ASV2228      1.750034e-02  1.782752e-02  1.815376e-02  1.847892e-02
## ASV2769      7.721058e-03  7.952117e-03  8.183963e-03  8.416233e-03
## ASV2803      1.552669e-02  1.582604e-02  1.612966e-02  1.643763e-02
## ASV2896      3.297151e-02  3.436754e-02  3.581926e-02  3.732860e-02
## ASV3062      4.255211e-02  4.407308e-02  4.562878e-02  4.721903e-02
## ASV3107      5.019192e-02  5.191135e-02  5.367467e-02  5.548221e-02
## ASV3265      3.836987e-02  3.914271e-02  3.991854e-02  4.069705e-02
## ASV3666     -1.109899e-03 -1.175786e-03 -1.243643e-03 -1.313476e-03
## ASV4497      1.532644e-02  1.570405e-02  1.608690e-02  1.647491e-02
## ASV6914     -6.199758e-03 -6.430779e-03 -6.667020e-03 -6.908464e-03
## ASV0576     -3.274664e-02 -3.315329e-02 -3.355217e-02 -3.394283e-02
## ASV0673      6.323350e-02  6.491256e-02  6.662319e-02  6.836582e-02
## ASV0772      3.419703e-02  3.526967e-02  3.636954e-02  3.749703e-02
## ASV0862      1.632300e-02  1.691175e-02  1.750786e-02  1.811087e-02
## ASV0898      3.384137e-02  3.493178e-02  3.604683e-02  3.718691e-02
## ASV0910      3.819565e-02  3.949897e-02  4.083532e-02  4.220495e-02
## ASV0964     -1.372978e-02 -1.394917e-02 -1.416878e-02 -1.438857e-02
## ASV10059     3.347840e-02  3.470792e-02  3.596942e-02  3.726299e-02
## ASV10263    -3.271651e-02 -3.333415e-02 -3.395131e-02 -3.456780e-02
## ASV1088      6.986048e-02  7.244271e-02  7.510508e-02  7.784905e-02
## ASV1101      4.690739e-02  4.786260e-02  4.882388e-02  4.979110e-02
## ASV1183      1.957278e-02  2.022356e-02  2.089323e-02  2.158231e-02
## ASV11956     9.736840e-03  9.959788e-03  1.018825e-02  1.042231e-02
## ASV12774    -4.354752e-03 -4.575059e-03 -4.802087e-03 -5.035863e-03
## ASV1321      1.006695e-01  1.039612e-01  1.073205e-01  1.107468e-01
## ASV13793    -2.257360e-02 -2.300278e-02 -2.343221e-02 -2.386180e-02
## ASV14482     1.939154e-03  2.033255e-03  2.131394e-03  2.233619e-03
## ASV15483     1.524537e-02  1.572352e-02  1.621269e-02  1.671305e-02
## ASV2062      5.741878e-02  5.903271e-02  6.067669e-02  6.235064e-02
## ASV2132      5.718936e-02  5.891714e-02  6.067601e-02  6.246569e-02
## ASV2413      4.022220e-02  4.131748e-02  4.243627e-02  4.357904e-02
## ASV2490      9.377795e-02  9.556598e-02  9.736326e-02  9.916964e-02
## ASV2594      2.483098e-02  2.581454e-02  2.683273e-02  2.788637e-02
## ASV2822     -5.961411e-02 -6.075697e-02 -6.190173e-02 -6.304810e-02
## ASV2863      6.649581e-02  6.803055e-02  6.958547e-02  7.116065e-02
## ASV2910      2.518357e-02  2.579151e-02  2.640971e-02  2.703841e-02
## ASV2980      3.333211e-02  3.422024e-02  3.512346e-02  3.604181e-02
## ASV3307      4.749448e-02  4.841301e-02  4.933396e-02  5.025709e-02
## ASV3474      6.173166e-02  6.384330e-02  6.600367e-02  6.821283e-02
## ASV3502      5.042202e-02  5.205803e-02  5.373867e-02  5.546490e-02
## ASV4236      3.976810e-02  4.040293e-02  4.103611e-02  4.166746e-02
## ASV4842     -3.458062e-03 -3.378963e-03 -3.290115e-03 -3.191252e-03
## ASV4894     -2.264517e-02 -2.308602e-02 -2.352824e-02 -2.397171e-02
## ASV5290      2.839871e-02  2.930422e-02  3.023361e-02  3.118746e-02
## ASV5501      2.208131e-02  2.301350e-02  2.398179e-02  2.498720e-02
## ASV5795      1.943561e-02  2.001362e-02  2.060104e-02  2.119769e-02
## ASV5987     -6.332163e-02 -6.456253e-02 -6.580785e-02 -6.705720e-02
## ASV6267     -7.139265e-02 -7.279580e-02 -7.420424e-02 -7.561756e-02
## ASV6862      2.825347e-02  2.889561e-02  2.954668e-02  3.020672e-02
## ASV7145      1.473948e-02  1.520046e-02  1.567418e-02  1.616086e-02
## ASV7673     -2.270528e-02 -2.315338e-02 -2.360326e-02 -2.405481e-02
## ASV7789      3.341849e-02  3.483787e-02  3.630479e-02  3.782014e-02
## ASV7809      6.815535e-03  7.095377e-03  7.381216e-03  7.672952e-03
## ASV8002     -2.872140e-02 -2.929229e-02 -2.986573e-02 -3.044156e-02
## ASV8205      1.952900e-02  2.014571e-02  2.077476e-02  2.141605e-02
## ASV9155     -5.144308e-03 -5.179765e-03 -5.212059e-03 -5.241091e-03
## ASV9221      1.724167e-02  1.807965e-02  1.895068e-02  1.985576e-02
## ASV9311     -4.618031e-02 -4.710607e-02 -4.803631e-02 -4.897079e-02
## ASV9557     -3.158355e-02 -3.221802e-02 -3.285560e-02 -3.349614e-02
## ASV9936     -6.373857e-02 -6.502154e-02 -6.631088e-02 -6.760629e-02
## ASV1445      5.980157e-02  6.159366e-02  6.341794e-02  6.527397e-02
## ASV4232      3.993966e-02  4.178595e-02  4.370827e-02  4.570876e-02
## ASV6479      2.611515e-02  2.736854e-02  2.866863e-02  3.001632e-02
## ASV0142     -2.821494e-02 -2.885230e-02 -2.949773e-02 -3.015130e-02
## ASV0378      2.464414e-02  2.540816e-02  2.618186e-02  2.696461e-02
## ASV1122      6.286611e-02  6.492465e-02  6.703209e-02  6.918873e-02
## ASV0123     -2.423480e-02 -2.475422e-02 -2.527838e-02 -2.580725e-02
## ASV2064      3.350086e-03  3.087463e-03  2.804331e-03  2.500194e-03
## ASV4459     -1.700956e-03 -1.830449e-03 -1.969719e-03 -2.119118e-03
## ASV0448      2.101427e-02  2.174377e-02  2.248859e-02  2.324838e-02
## ASV0397      2.942633e-02  3.023155e-02  3.105056e-02  3.188340e-02
## ASV0485      3.191779e-02  3.276647e-02  3.362871e-02  3.450438e-02
## ASV1566      4.965301e-02  5.099054e-02  5.234863e-02  5.372700e-02
## ASV1365      4.324107e-02  4.433835e-02  4.544925e-02  4.657388e-02
## ASV1065      6.581420e-02  6.770199e-02  6.962284e-02  7.157662e-02
## ASV0722     -6.790335e-03 -7.120396e-03 -7.464803e-03 -7.823980e-03
## ASV12660    -2.531130e-02 -2.582921e-02 -2.635098e-02 -2.687659e-02
## ASV0223      1.000553e-02  1.032556e-02  1.065395e-02  1.099077e-02
## ASV0229      1.950270e-02  2.021385e-02  2.094779e-02  2.170513e-02
## ASV0877     -6.280334e-03 -6.954257e-03 -7.670920e-03 -8.431950e-03
## ASV0983      2.810023e-02  2.872049e-02  2.934421e-02  2.997111e-02
## ASV0626      1.261072e-02  1.310701e-02  1.361597e-02  1.413766e-02
## ASV4146     -6.364162e-03 -6.930895e-03 -7.530722e-03 -8.164436e-03
## ASV4175     -4.891023e-02 -5.035419e-02 -5.182230e-02 -5.331427e-02
## ASV2082     -5.285506e-02 -5.523034e-02 -5.768439e-02 -6.021787e-02
## ASV2272      2.548172e-02  2.636564e-02  2.727435e-02  2.820828e-02
## ASV2245     -3.607567e-02 -3.715280e-02 -3.824794e-02 -3.936086e-02
## ASV0590     -5.480341e-02 -5.730441e-02 -5.989215e-02 -6.256781e-02
## ASV0217      1.668970e-02  1.748066e-02  1.829946e-02  1.914679e-02
## ASV0416      4.754711e-03  4.478559e-03  4.182503e-03  3.866242e-03
## ASV1056      3.824959e-02  3.944144e-02  4.065445e-02  4.188826e-02
## ASV7777     -5.310400e-02 -5.513329e-02 -5.724200e-02 -5.943367e-02
## ASV0455      6.723073e-03  6.852119e-03  6.978418e-03  7.101606e-03
## ASV0604      2.797533e-02  2.893361e-02  2.991432e-02  3.091742e-02
## ASV6100     -4.073659e-02 -4.233874e-02 -4.399961e-02 -4.572109e-02
## ASV11359    -6.510155e-02 -6.683850e-02 -6.859428e-02 -7.036820e-02
## ASV6604      1.124460e-02  1.155501e-02  1.186501e-02  1.217389e-02
## ASV5004     -2.549252e-02 -2.635702e-02 -2.724562e-02 -2.815861e-02
## ASV1483     -8.954829e-03 -9.166347e-03 -9.377681e-03 -9.588522e-03
## ASV9773     -3.543776e-02 -3.669328e-02 -3.798644e-02 -3.931801e-02
## ASV4059      1.125094e-02  1.170588e-02  1.216397e-02  1.262407e-02
## ASV1193      3.426541e-02  3.524623e-02  3.624448e-02  3.725999e-02
## ASV4610      4.849762e-03  5.034720e-03  5.216234e-03  5.393636e-03
## ASV0742      7.154682e-03  7.471974e-03  7.793825e-03  8.119965e-03
## ASV1502     -9.056877e-03 -9.408184e-03 -9.764953e-03 -1.012684e-02
## ASV0195     -3.771479e-03 -3.967086e-03 -4.169573e-03 -4.379092e-03
## ASV1213      1.180329e-02  1.189007e-02  1.196915e-02  1.204018e-02
## ASV1648     -3.730722e-02 -3.879938e-02 -4.034538e-02 -4.194656e-02
## ASV6984     -3.589842e-02 -3.735868e-02 -3.887261e-02 -4.044162e-02
## ASV0396     -1.561142e-04 -3.180364e-04 -5.012974e-04 -7.074515e-04
## ASV4297      2.192337e-02  2.234950e-02  2.278201e-02  2.322128e-02
## ASV2622      4.378513e-02  4.485544e-02  4.594122e-02  4.704250e-02
## ASV3512      4.811786e-02  5.033106e-02  5.263100e-02  5.501998e-02
## ASV2411      5.088317e-02  5.256299e-02  5.427386e-02  5.601496e-02
## ASV2291     -4.581573e-02 -4.776174e-02 -4.976566e-02 -5.182796e-02
## ASV0807      4.742195e-02  4.867490e-02  4.994943e-02  5.124604e-02
## ASV1292      5.302354e-03  5.416217e-03  5.538365e-03  5.669530e-03
## ASV1035      3.771861e-02  3.874201e-02  3.978910e-02  4.086051e-02
## ASV0070      7.322286e-03  7.700136e-03  8.091785e-03  8.497419e-03
## ASV0255     -2.076183e-03 -2.384482e-03 -2.713752e-03 -3.064772e-03
## ASV0057     -5.212984e-03 -5.190353e-03 -5.160864e-03 -5.124391e-03
## ASV0077     -5.869583e-06 -1.286485e-05 -2.576790e-05 -4.527712e-05
## ASV0625      1.719780e-02  1.750925e-02  1.782149e-02  1.813452e-02
## ASV2464      1.230041e-01  1.255056e-01  1.280240e-01  1.305588e-01
## ASV1315      6.887069e-02  7.122752e-02  7.363499e-02  7.609252e-02
## ASV2673      6.088898e-02  6.307492e-02  6.531723e-02  6.761612e-02
## ASV2161      2.725991e-02  2.832453e-02  2.942237e-02  3.055387e-02
## ASV0337     -1.208125e-02 -1.248609e-02 -1.290118e-02 -1.332658e-02
## ASV7680     -8.070062e-02 -8.331854e-02 -8.599105e-02 -8.871763e-02
## ASV0611      4.800433e-02  4.972833e-02  5.150335e-02  5.333041e-02
## ASV3118     -5.672544e-02 -5.874158e-02 -6.080831e-02 -6.292599e-02
## ASV1284     -3.431826e-02 -3.670210e-02 -3.920500e-02 -4.183062e-02
## ASV0889      2.690234e-02  2.779940e-02  2.872723e-02  2.968693e-02
## ASV4649     -1.573872e-02 -1.625168e-02 -1.677743e-02 -1.731612e-02
## ASV1108     -4.880869e-02 -5.068619e-02 -5.261675e-02 -5.460086e-02
## ASV0738      3.947687e-02  4.131352e-02  4.322372e-02  4.520972e-02
## ASV0473     -5.595856e-03 -5.617721e-03 -5.621096e-03 -5.604270e-03
## ASV0598     -2.487552e-02 -2.606051e-02 -2.728929e-02 -2.856259e-02
## ASV0429      1.224601e-02  1.239468e-02  1.253945e-02  1.268040e-02
## ASV1549      5.584385e-02  5.775196e-02  5.969743e-02  6.167920e-02
## ASV1203      2.527511e-02  2.585700e-02  2.644249e-02  2.703129e-02
## ASV4532      1.390655e-03  1.532700e-03  1.687268e-03  1.855035e-03
## ASV0274      6.762502e-03  6.878438e-03  6.986810e-03  7.086852e-03
## ASV0163     -1.720677e-02 -1.767930e-02 -1.816593e-02 -1.866725e-02
## ASV1298      5.114985e-03  5.506144e-03  5.923821e-03  6.369166e-03
## ASV9424     -7.128423e-02 -7.399301e-02 -7.678918e-02 -7.967457e-02
## ASV0412      4.328760e-02  4.435688e-02  4.544223e-02  4.654392e-02
## ASV0284     -2.237802e-03 -2.691239e-03 -3.175176e-03 -3.690848e-03
## ASV0620     -2.442709e-02 -2.544695e-02 -2.649912e-02 -2.758411e-02
## ASV0153     -7.220351e-02 -7.462113e-02 -7.708755e-02 -7.960207e-02
## ASV0498      1.745658e-02  1.780064e-02  1.813820e-02  1.846855e-02
## ASV0097      1.466946e-02  1.516948e-02  1.567919e-02  1.619834e-02
## ASV0104     -6.284844e-02 -6.436118e-02 -6.588688e-02 -6.742496e-02
## ASV1282      9.248482e-03  8.998248e-03  8.714855e-03  8.397001e-03
## ASV3883     -3.224609e-02 -3.330128e-02 -3.436995e-02 -3.545094e-02
## ASV0801      1.383712e-02  1.443050e-02  1.504925e-02  1.569425e-02
## ASV1611     -6.430553e-02 -6.659049e-02 -6.893394e-02 -7.133614e-02
## ASV0227     -2.154127e-02 -2.247803e-02 -2.344694e-02 -2.444876e-02
## ASV0833      1.727271e-02  1.779449e-02  1.832678e-02  1.886960e-02
## ASV0718      7.858614e-02  8.101229e-02  8.348725e-02  8.601089e-02
## ASV1139     -7.922097e-03 -8.542270e-03 -9.188124e-03 -9.859868e-03
## ASV0766     -1.633717e-02 -1.689071e-02 -1.745395e-02 -1.802662e-02
## ASV2091      3.407805e-02  3.457464e-02  3.506429e-02  3.554683e-02
## ASV1238     -8.126515e-02 -8.472880e-02 -8.832677e-02 -9.206284e-02
## ASV9193     -2.475463e-02 -2.602873e-02 -2.735319e-02 -2.872894e-02
## ASV0290      3.098050e-03  3.238859e-03  3.390720e-03  3.554108e-03
## ASV0231      1.479197e-02  1.501290e-02  1.522611e-02  1.543109e-02
## ASV0185      2.926364e-02  3.058012e-02  3.194489e-02  3.335907e-02
## ASV2330      1.360665e-02  1.387482e-02  1.414810e-02  1.442665e-02
## ASV3119     -2.481822e-02 -2.589638e-02 -2.701142e-02 -2.816398e-02
## ASV2368     -4.738919e-02 -4.943928e-02 -5.156466e-02 -5.376692e-02
## ASV0122     -1.158127e-02 -1.189780e-02 -1.222088e-02 -1.255069e-02
## ASV1044      4.772633e-02  4.952409e-02  5.137743e-02  5.328738e-02
## ASV0160     -9.180382e-03 -9.437073e-03 -9.703847e-03 -9.981206e-03
## ASV0326      2.774499e-03  2.786302e-03  2.792921e-03  2.794001e-03
## ASV1388      5.877976e-02  6.023828e-02  6.171427e-02  6.320759e-02
## ASV0792      3.497397e-02  3.566264e-02  3.635409e-02  3.704830e-02
## ASV0036     -2.035686e-02 -2.096447e-02 -2.157825e-02 -2.219758e-02
## ASV2125      4.393650e-02  4.501816e-02  4.610778e-02  4.720463e-02
## ASV1075     -2.434165e-03 -2.588344e-03 -2.750673e-03 -2.921393e-03
## ASV0390      4.230077e-02  4.404594e-02  4.585178e-02  4.771951e-02
## ASV3790     -4.481744e-02 -4.633072e-02 -4.788209e-02 -4.947188e-02
## ASV1535     -2.090534e-02 -2.169816e-02 -2.250986e-02 -2.334038e-02
## ASV0263      4.749337e-02  4.890994e-02  5.035333e-02  5.182348e-02
## ASV0675      8.726457e-02  9.024767e-02  9.330361e-02  9.643271e-02
## ASV3348      8.742535e-03  9.029220e-03  9.319261e-03  9.612235e-03
## ASV0058     -1.661257e-02 -1.699431e-02 -1.737848e-02 -1.776487e-02
## ASV4142      1.933351e-02  1.976570e-02  2.020546e-02  2.065308e-02
## ASV0059     -1.244386e-02 -1.271196e-02 -1.298177e-02 -1.325326e-02
## ASV0013     -2.924170e-02 -3.009868e-02 -3.097276e-02 -3.186409e-02
## ASV0033     -1.778983e-02 -1.834288e-02 -1.890408e-02 -1.947309e-02
## ASV4354     -2.038010e-02 -2.106614e-02 -2.176725e-02 -2.248330e-02
## ASV0022     -1.533756e-02 -1.582852e-02 -1.632728e-02 -1.683349e-02
## ASV0134     -2.138125e-02 -2.235917e-02 -2.337859e-02 -2.444099e-02
## ASV0415      3.524633e-03  3.636704e-03  3.750828e-03  3.867068e-03
## ASV10103    -8.289556e-02 -8.569259e-02 -8.855217e-02 -9.147402e-02
## ASV1613      2.963346e-02  2.998924e-02  3.032893e-02  3.065192e-02
## ASV0135     -2.305020e-03 -2.287446e-03 -2.266347e-03 -2.241649e-03
## ASV0469     -5.656943e-02 -5.823881e-02 -5.994763e-02 -6.169657e-02
## ASV0471      3.993977e-02  4.127764e-02  4.265739e-02  4.408039e-02
## ASV0451     -1.676306e-02 -1.744109e-02 -1.813647e-02 -1.884920e-02
## ASV0747      2.205912e-02  2.264443e-02  2.323484e-02  2.383001e-02
## ASV1314     -3.571449e-02 -3.718061e-02 -3.869645e-02 -4.026299e-02
## ASV0425     -5.251084e-02 -5.362178e-02 -5.474320e-02 -5.587504e-02
## ASV0559     -2.452289e-02 -2.551849e-02 -2.654953e-02 -2.761659e-02
## ASV0148      5.353091e-03  5.785472e-03  6.240865e-03  6.720094e-03
## ASV0129      2.276806e-02  2.391975e-02  2.511544e-02  2.635591e-02
## ASV1072     -1.258245e-03 -1.450632e-03 -1.652005e-03 -1.862352e-03
## ASV2390      1.492365e-02  1.478807e-02  1.462915e-02  1.444651e-02
## ASV0548      2.409187e-02  2.473278e-02  2.538343e-02  2.604385e-02
## ASV0168     -1.123324e-02 -1.153088e-02 -1.183401e-02 -1.214270e-02
## ASV0066     -1.135380e-02 -1.154409e-02 -1.172909e-02 -1.190829e-02
## ASV0468     -9.736991e-03 -1.010237e-02 -1.048041e-02 -1.087145e-02
## ASV0172      1.027940e-03  1.204364e-03  1.391051e-03  1.588289e-03
## ASV0236      1.854366e-02  1.949902e-02  2.048604e-02  2.150481e-02
## ASV0250      4.389317e-02  4.584073e-02  4.786033e-02  4.995361e-02
## ASV0338      1.046253e-02  1.067790e-02  1.088882e-02  1.109469e-02
## ASV0450     -6.842167e-03 -7.168599e-03 -7.506015e-03 -7.854411e-03
## ASV0377      1.418055e-02  1.441837e-02  1.464934e-02  1.487279e-02
## ASV1022      2.562635e-03  2.795017e-03  3.042911e-03  3.307022e-03
## ASV6174     -2.142931e-03 -2.140219e-03 -2.124628e-03 -2.094807e-03
## ASV0786     -7.845056e-03 -8.090328e-03 -8.334312e-03 -8.576315e-03
## ASV0053     -2.103022e-02 -2.164267e-02 -2.226636e-02 -2.290135e-02
## ASV0697     -1.041378e-02 -1.075169e-02 -1.110368e-02 -1.147066e-02
## ASV0785      2.240802e-02  2.302157e-02  2.365004e-02  2.429410e-02
## ASV1967     -2.223841e-02 -2.281665e-02 -2.340191e-02 -2.399392e-02
## ASV0385      1.021071e-02  1.043360e-02  1.065152e-02  1.086382e-02
## ASV0295      8.731265e-03  9.180387e-03  9.647407e-03  1.013273e-02
## ASV0072     -1.251364e-02 -1.264999e-02 -1.277796e-02 -1.289722e-02
## ASV0157      9.173970e-03  9.792287e-03  1.044092e-02  1.112078e-02
## ASV0501      4.420378e-02  4.535152e-02  4.650921e-02  4.767640e-02
## ASV10729    -6.510666e-02 -6.722697e-02 -6.939613e-02 -7.161452e-02
## ASV1470      9.709666e-03  9.503206e-03  9.268393e-03  9.004094e-03
## ASV0050     -3.968958e-02 -4.061349e-02 -4.154374e-02 -4.247995e-02
## ASV0411     -1.604973e-02 -1.671441e-02 -1.740559e-02 -1.812427e-02
## ASV0549      2.101343e-02  2.168280e-02  2.236473e-02  2.305895e-02
## ASV0184      7.186878e-03  7.495536e-03  7.818542e-03  8.156581e-03
## ASV0705      6.332658e-03  6.335531e-03  6.326932e-03  6.306149e-03
## ASV1715      2.480646e-02  2.552392e-02  2.625405e-02  2.699683e-02
## ASV0603      8.231749e-03  8.665240e-03  9.119031e-03  9.593678e-03
## ASV0826      3.911612e-02  4.026322e-02  4.143548e-02  4.263325e-02
## ASV0034     -9.259090e-03 -9.433522e-03 -9.607588e-03 -9.781242e-03
## ASV0838     -2.308978e-02 -2.488736e-02 -2.678638e-02 -2.879036e-02
## ASV0614     -1.051199e-02 -1.081471e-02 -1.112416e-02 -1.144049e-02
## ASV0014     -2.778322e-02 -2.852398e-02 -2.927472e-02 -3.003526e-02
## ASV0585     -1.050851e-02 -1.100631e-02 -1.151242e-02 -1.202619e-02
## ASV0016     -2.914126e-02 -2.992407e-02 -3.071795e-02 -3.152276e-02
## ASV5394     -2.365333e-02 -2.423635e-02 -2.481573e-02 -2.538991e-02
## ASV0666      3.514933e-02  3.586962e-02  3.659511e-02  3.732583e-02
## ASV2085     -1.440497e-02 -1.545929e-02 -1.656432e-02 -1.772164e-02
## ASV0003     -1.986878e-02 -2.040849e-02 -2.095658e-02 -2.151302e-02
## ASV0346      1.304319e-02  1.340491e-02  1.376925e-02  1.413592e-02
## ASV0267      2.592754e-03  2.587099e-03  2.567405e-03  2.532307e-03
## ASV0353      2.226924e-02  2.303047e-02  2.380912e-02  2.460509e-02
## ASV2419      3.837530e-02  3.921819e-02  4.005641e-02  4.088843e-02
## ASV0447      3.279483e-02  3.394726e-02  3.513179e-02  3.634902e-02
## ASV0654      3.398865e-02  3.486810e-02  3.575863e-02  3.666013e-02
## ASV0151      1.155890e-02  1.203070e-02  1.251460e-02  1.301048e-02
## ASV0065     -1.230848e-02 -1.262553e-02 -1.294757e-02 -1.327466e-02
## ASV0527      3.212222e-02  3.295014e-02  3.378568e-02  3.462821e-02
## ASV4055     -1.574211e-02 -1.666185e-02 -1.763351e-02 -1.865964e-02
## ASV0166     -1.220210e-02 -1.246904e-02 -1.274075e-02 -1.301752e-02
## ASV0417     -1.938426e-03 -1.900668e-03 -1.861525e-03 -1.821392e-03
## ASV0078     -5.980787e-03 -5.998169e-03 -6.006328e-03 -6.004721e-03
## ASV0322      8.455767e-03  9.037135e-03  9.645881e-03  1.028260e-02
## ASV0156     -3.129660e-02 -3.244331e-02 -3.362717e-02 -3.484924e-02
## ASV0648     -6.552872e-02 -6.763129e-02 -6.977188e-02 -7.194932e-02
## ASV0407     -7.156978e-03 -7.470085e-03 -7.795032e-03 -8.132116e-03
## ASV2030     -1.422583e-02 -1.489568e-02 -1.559217e-02 -1.631575e-02
## ASV0300      8.746528e-03  9.026290e-03  9.310388e-03  9.598632e-03
## ASV1150      2.559053e-03  2.615876e-03  2.670091e-03  2.721354e-03
## ASV0958      3.285089e-02  3.419288e-02  3.557994e-02  3.701298e-02
## ASV0216     -2.428217e-02 -2.522083e-02 -2.619546e-02 -2.720716e-02
## ASV0446      3.841644e-02  3.958573e-02  4.077496e-02  4.198381e-02
## ASV0367     -2.391354e-02 -2.464835e-02 -2.539706e-02 -2.615950e-02
## ASV0200     -1.274577e-02 -1.305410e-02 -1.336118e-02 -1.366636e-02
## ASV0334     -2.087478e-03 -2.163750e-03 -2.249393e-03 -2.345203e-03
## ASV1311      8.480640e-05 -1.349577e-04 -3.696705e-04 -6.198532e-04
## ASV0458      1.337213e-03  1.147367e-03  9.459028e-04  7.326570e-04
## ASV1371      2.243546e-03  2.262882e-03  2.278474e-03  2.290118e-03
## ASV0418      1.950917e-02  1.990555e-02  2.030540e-02  2.070896e-02
## ASV0004      2.514874e-03  2.555511e-03  2.595798e-03  2.635706e-03
## ASV1943      1.999023e-02  1.973171e-02  1.945155e-02  1.914989e-02
## ASV1495     -2.320491e-02 -2.432737e-02 -2.548934e-02 -2.669121e-02
## ASV0901     -3.527990e-02 -3.668349e-02 -3.813588e-02 -3.963825e-02
## ASV0628      3.217445e-03  3.035873e-03  2.835847e-03  2.616495e-03
## ASV0400      3.130754e-03  3.022047e-03  2.897179e-03  2.755213e-03
## ASV0116     -9.705215e-03 -1.006356e-02 -1.043262e-02 -1.081258e-02
## ASV0788      8.990124e-02  9.342521e-02  9.707405e-02  1.008518e-01
## ASV0117      7.525673e-03  7.811873e-03  8.106818e-03  8.410752e-03
## ASV3137     -4.933919e-04 -4.493171e-04 -3.989076e-04 -3.416737e-04
## ASV0001      2.536331e-03  2.581459e-03  2.627538e-03  2.674683e-03
## ASV1651      8.758452e-03  8.975302e-03  9.199129e-03  9.430481e-03
## ASV1692      7.081772e-02  7.345308e-02  7.617464e-02  7.898497e-02
## ASV0660      1.464155e-03  1.053640e-03  6.166433e-04  1.527480e-04
## ASV0508     -2.732334e-04 -3.363050e-04 -4.053607e-04 -4.808140e-04
## ASV1660     -1.727664e-02 -1.783163e-02 -1.839224e-02 -1.895776e-02
## ASV0233      1.782599e-02  1.839441e-02  1.897707e-02  1.957427e-02
## ASV1343     -4.015604e-02 -4.165425e-02 -4.319988e-02 -4.479401e-02
## ASV0209      7.627737e-03  7.660175e-03  7.683696e-03  7.697861e-03
## ASV0193     -9.040900e-03 -9.063049e-03 -9.073484e-03 -9.071697e-03
## ASV0357      1.928179e-02  2.024658e-02  2.125114e-02  2.229636e-02
## ASV0198      1.254066e-02  1.293523e-02  1.334074e-02  1.375745e-02
## ASV0007      1.711473e-03  1.727183e-03  1.743153e-03  1.759498e-03
## ASV1772      9.565916e-03  1.061541e-02  1.174619e-02  1.296302e-02
## ASV0009      1.016873e-03  1.016192e-03  1.015924e-03  1.016229e-03
## ASV0006     -5.487651e-03 -5.684556e-03 -5.886106e-03 -6.092286e-03
## ASV0011     -1.505789e-02 -1.556507e-02 -1.608494e-02 -1.661761e-02
## ASV0015      4.075627e-04  3.714569e-04  3.325495e-04  2.907459e-04
## ASV0017      7.316738e-04  7.104018e-04  6.870522e-04  6.615583e-04
## ASV0235     -1.483259e-02 -1.537753e-02 -1.594015e-02 -1.652096e-02
## ASV0382      6.002358e-03  5.938453e-03  5.854025e-03  5.747803e-03
## ASV2357      4.640175e-02  4.798919e-02  4.961363e-02  5.127467e-02
## ASV0567     -1.240575e-02 -1.297916e-02 -1.357672e-02 -1.419912e-02
## ASV0165      6.856002e-03  7.059930e-03  7.267780e-03  7.479599e-03
## ASV0005      7.982474e-03  8.171772e-03  8.361989e-03  8.552990e-03
## ASV0384      5.292200e-03  5.651679e-03  6.030194e-03  6.428457e-03
## ASV0002      1.371924e-03  1.408615e-03  1.445854e-03  1.483625e-03
## ASV3017      2.912342e-02  2.955691e-02  2.998392e-02  3.040429e-02
## ASV0091     -2.270507e-03 -2.409399e-03 -2.556919e-03 -2.713494e-03
## ASV0186     -1.627192e-02 -1.663282e-02 -1.699297e-02 -1.735203e-02
## ASV0370      8.437344e-03  8.692739e-03  8.956592e-03  9.229328e-03
## ASV0018      1.079930e-02  1.107832e-02  1.136046e-02  1.164564e-02
## ASV1377      8.151365e-02  8.315412e-02  8.480340e-02  8.646173e-02
## ASV0019      1.158876e-02  1.189892e-02  1.221334e-02  1.253197e-02
## ASV0023     -9.069982e-03 -9.342187e-03 -9.618233e-03 -9.897974e-03
## ASV2194      1.921470e-02  1.998547e-02  2.078130e-02  2.160256e-02
## ASV1155      4.197257e-02  4.326825e-02  4.460382e-02  4.598080e-02
## ASV0510     -6.490834e-03 -6.639152e-03 -6.792009e-03 -6.949410e-03
## ASV2371     -2.199166e-02 -2.247084e-02 -2.295188e-02 -2.343457e-02
## ASV0024     -1.118069e-02 -1.152013e-02 -1.186493e-02 -1.221495e-02
## ASV2452      1.079642e-02  1.071907e-02  1.062769e-02  1.052213e-02
## ASV2332     -7.502162e-02 -7.717404e-02 -7.937013e-02 -8.161000e-02
## ASV2591      3.347056e-02  3.444962e-02  3.543821e-02  3.643570e-02
## ASV0521      2.445031e-02  2.530510e-02  2.618323e-02  2.708506e-02
## ASV5542      2.135626e-02  2.204567e-02  2.275167e-02  2.347446e-02
## ASV0336     -7.970664e-03 -8.372005e-03 -8.792624e-03 -9.233475e-03
## ASV10102     3.859706e-02  3.974411e-02  4.091013e-02  4.209490e-02
## ASV16823    -3.314881e-02 -3.382853e-02 -3.451466e-02 -3.520726e-02
## ASV3104      1.714969e-01  1.750125e-01  1.785611e-01  1.821432e-01
## ASV0781      3.934690e-02  4.062776e-02  4.194374e-02  4.329551e-02
## ASV10899     4.900857e-02  5.111509e-02  5.329337e-02  5.554476e-02
## ASV11222    -5.833019e-02 -5.952553e-02 -6.073212e-02 -6.195008e-02
## ASV11327    -5.236465e-02 -5.343754e-02 -5.452053e-02 -5.561371e-02
## ASV12458    -5.831843e-02 -5.951313e-02 -6.071908e-02 -6.193638e-02
## ASV1636      4.147758e-02  4.251397e-02  4.356732e-02  4.463793e-02
## ASV1890     -2.026751e-02 -2.067802e-02 -2.110311e-02 -2.154385e-02
## ASV2898      5.647313e-02  5.793006e-02  5.941512e-02  6.092900e-02
## ASV8328      4.842557e-02  5.074079e-02  5.313235e-02  5.560060e-02
## ASV0709     -6.741896e-02 -6.910826e-02 -7.081772e-02 -7.254694e-02
## ASV0856      8.659110e-02  8.948102e-02  9.243131e-02  9.544141e-02
## ASV0909      5.063807e-02  5.280943e-02  5.504843e-02  5.735590e-02
## ASV0937     -6.465477e-02 -6.719576e-02 -6.981903e-02 -7.252567e-02
## ASV11390    -8.321395e-02 -8.491827e-02 -8.663868e-02 -8.837537e-02
## ASV11966     4.582965e-02  4.734511e-02  4.888914e-02  5.046127e-02
## ASV12990     1.662625e-02  1.701859e-02  1.741604e-02  1.781841e-02
## ASV14797     2.343657e-02  2.397591e-02  2.452338e-02  2.507900e-02
## ASV14904    -1.193967e-01 -1.218420e-01 -1.243104e-01 -1.268022e-01
## ASV15304     3.411629e-02  3.529724e-02  3.650125e-02  3.772791e-02
## ASV16696    -4.125232e-02 -4.209726e-02 -4.295023e-02 -4.381131e-02
## ASV1690      1.312434e-01  1.349614e-01  1.387201e-01  1.425172e-01
## ASV2029      6.993423e-02  7.189152e-02  7.388489e-02  7.591438e-02
## ASV2834      1.032188e-01  1.061878e-01  1.092025e-01  1.122620e-01
## ASV4003      1.491669e-01  1.559256e-01  1.629622e-01  1.702860e-01
## ASV4064      5.335680e-02  5.510357e-02  5.689535e-02  5.873304e-02
## ASV4294      5.703023e-02  5.946634e-02  6.198505e-02  6.458783e-02
## ASV4609      2.556018e-02  2.639499e-02  2.725195e-02  2.813124e-02
## ASV6283     -3.855980e-02 -3.934971e-02 -4.014714e-02 -4.095219e-02
## ASV6491     -5.526813e-02 -5.640050e-02 -5.754368e-02 -5.869780e-02
## ASV7453      6.369264e-02  6.586201e-02  6.807575e-02  7.033342e-02
## ASV7959      3.998846e-02  4.179598e-02  4.367077e-02  4.561455e-02
## ASV8219      4.776501e-01  4.874402e-01  4.973241e-01  5.073029e-01
## ASV8547     -4.948466e-02 -5.049916e-02 -5.152341e-02 -5.255751e-02
## ASV9319      4.912523e-02  5.103535e-02  5.300935e-02  5.504880e-02
## ASV9382     -9.682726e-02 -9.881294e-02 -1.008177e-01 -1.028419e-01
## ASV11516    -6.467584e-02 -6.600256e-02 -6.734209e-02 -6.869457e-02
## ASV14377    -4.670191e-02 -4.766021e-02 -4.862779e-02 -4.960474e-02
## ASV1867      7.066293e-02  7.314364e-02  7.569691e-02  7.832425e-02
## ASV1895      7.137095e-03  6.819002e-03  6.474505e-03  6.103154e-03
## ASV3168      2.033031e-02  2.059782e-02  2.085952e-02  2.111515e-02
## ASV4449      2.146955e-01  2.218759e-01  2.292587e-01  2.368484e-01
## ASV6596      7.840694e-02  8.166700e-02  8.502994e-02  8.849663e-02
## ASV7492      1.765529e-02  1.863804e-02  1.965181e-02  2.069633e-02
## ASV9854     -9.163734e-03 -9.331783e-03 -9.500993e-03 -9.671487e-03
## ASV6296      7.838271e-01  7.999260e-01  8.161820e-01  8.325968e-01
## ASV4201      3.999594e-02  4.209710e-02  4.428813e-02  4.657181e-02
## ASV0552      4.354585e-02  4.479274e-02  4.605414e-02  4.732909e-02
## ASV3671     -3.454659e-02 -3.604664e-02 -3.760851e-02 -3.923390e-02
## ASV3529      7.171061e-03  7.484724e-03  7.799698e-03  8.115379e-03
## ASV1060      1.898571e-02  1.985459e-02  2.075979e-02  2.170249e-02
## ASV0239     -6.354840e-03 -6.377504e-03 -6.393194e-03 -6.401474e-03
## ASV5711     -5.700937e-02 -5.855827e-02 -6.013064e-02 -6.172606e-02
## ASV4152     -9.516871e-02 -9.788705e-02 -1.006435e-01 -1.034371e-01
## ASV1461      2.262930e-02  2.285977e-02  2.308081e-02  2.329203e-02
## ASV2877      1.145201e-02  1.147025e-02  1.147317e-02  1.145998e-02
## ASV0012      4.363800e-03  4.499896e-03  4.638948e-03  4.780972e-03
## ASV9823     -8.295023e-03 -8.941027e-03 -9.617849e-03 -1.032606e-02
## ASV0008      4.508468e-03  4.648203e-03  4.791008e-03  4.936898e-03
## ASV7832     -6.371082e-02 -6.581867e-02 -6.797560e-02 -7.018189e-02
## ASV1915     -8.825810e-03 -9.206354e-03 -9.601784e-03 -1.001254e-02
## ASV0055     -9.933625e-03 -1.036379e-02 -1.080934e-02 -1.127063e-02
## ASV0032      3.356487e-04  3.491746e-04  3.666833e-04  3.886165e-04
## ASV2977     -7.523166e-02 -7.727399e-02 -7.934053e-02 -8.143054e-02
## ASV0466      2.832134e-02  2.846405e-02  2.858405e-02  2.868052e-02
## ASV3866      5.729387e-02  5.948433e-02  6.174584e-02  6.407989e-02
## ASV0040      1.674789e-02  1.726895e-02  1.780030e-02  1.834189e-02
## ASV0496     -1.743802e-02 -1.819705e-02 -1.897532e-02 -1.977255e-02
## ASV0052      1.465064e-02  1.515310e-02  1.567049e-02  1.620322e-02
## ASV3828     -2.682349e-02 -2.734087e-02 -2.786177e-02 -2.838625e-02
## ASV1930      1.359302e-02  1.378531e-02  1.397400e-02  1.415888e-02
## ASV2126      3.613392e-02  3.721689e-02  3.832527e-02  3.945942e-02
## ASV0793      5.847542e-02  6.051652e-02  6.261828e-02  6.478246e-02
## ASV0299     -6.925758e-03 -7.413244e-03 -7.928502e-03 -8.472488e-03
## ASV0208      4.065503e-02  4.209938e-02  4.358764e-02  4.512080e-02
## ASV0511     -7.050067e-03 -7.206728e-03 -7.369510e-03 -7.538720e-03
## ASV1123     -2.048650e-02 -2.055610e-02 -2.059730e-02 -2.060817e-02
## ASV0099      4.634707e-03  4.875778e-03  5.126594e-03  5.387351e-03
## ASV0752     -3.604743e-02 -3.742855e-02 -3.885270e-02 -4.032061e-02
## ASV0883      4.359894e-02  4.498606e-02  4.639642e-02  4.782944e-02
## ASV0683      5.714664e-02  5.913276e-02  6.116843e-02  6.325390e-02
## ASV4117     -8.376410e-02 -8.669839e-02 -8.971483e-02 -9.281486e-02
## ASV2172     -3.564900e-03 -3.913038e-03 -4.281178e-03 -4.669961e-03
## ASV0330     -1.671403e-02 -1.734275e-02 -1.799252e-02 -1.866389e-02
## ASV0728      6.258611e-02  6.444194e-02  6.634070e-02  6.828336e-02
## ASV0499      2.354500e-02  2.439837e-02  2.527474e-02  2.617428e-02
## ASV0120     -2.614329e-02 -2.677022e-02 -2.739789e-02 -2.802546e-02
## ASV1446     -4.782235e-03 -5.625537e-03 -6.520387e-03 -7.468445e-03
## ASV17171    -6.269433e-02 -6.487751e-02 -6.712079e-02 -6.942463e-02
## ASV0533      7.080591e-03  7.345123e-03  7.616093e-03  7.893485e-03
## ASV2495     -3.092613e-02 -3.219267e-02 -3.349261e-02 -3.482577e-02
## ASV5582      3.459971e-03  3.017644e-03  2.536369e-03  2.014020e-03
## ASV1488      3.483511e-03  3.361544e-03  3.224165e-03  3.070711e-03
## ASV0682      1.694959e-02  1.752420e-02  1.811049e-02  1.870823e-02
## ASV0068     -2.007443e-02 -2.053597e-02 -2.099623e-02 -2.145463e-02
## ASV1987     -7.858390e-02 -8.143567e-02 -8.436197e-02 -8.736325e-02
## ASV0035     -1.895252e-02 -2.000853e-02 -2.111307e-02 -2.226752e-02
## ASV7192     -2.631095e-02 -2.686010e-02 -2.740703e-02 -2.795117e-02
## ASV0873     -1.221305e-01 -1.273876e-01 -1.327740e-01 -1.382891e-01
## ASV4749     -3.146768e-02 -3.307722e-02 -3.474454e-02 -3.647049e-02
## ASV2174      4.404007e-03  4.120332e-03  3.816542e-03  3.492408e-03
## ASV1476     -3.616642e-02 -3.755821e-02 -3.899227e-02 -4.046939e-02
## ASV0740     -9.785572e-02 -1.016504e-01 -1.055688e-01 -1.096136e-01
## ASV0170     -1.484346e-02 -1.534185e-02 -1.585381e-02 -1.637956e-02
## ASV2466     -7.042882e-02 -7.281342e-02 -7.525741e-02 -7.776096e-02
## ASV1709      3.052544e-02  3.208624e-02  3.373181e-02  3.546606e-02
## ASV6170     -1.207583e-01 -1.249182e-01 -1.291774e-01 -1.335357e-01
## ASV3673      6.358094e-02  6.581440e-02  6.810050e-02  7.043893e-02
## ASV1745     -2.120392e-02 -2.203653e-02 -2.289313e-02 -2.377393e-02

stats::glm for first 500

library(stats)

logreg_500 <- stats::glm(as.factor(Clade) ~ . ,
                          data = lr_clr_df_500[,-1],
                          family = "binomial")
summary(logreg_500)
## 
## Call:
## stats::glm(formula = as.factor(Clade) ~ ., family = "binomial", 
##     data = lr_clr_df_500[, -1])
## 
## Coefficients: (269 not defined because of singularities)
##               Estimate Std. Error   z value Pr(>|z|)    
## (Intercept)  3.365e+24  7.553e+17   4455140   <2e-16 ***
## ASV1236      6.734e+28  7.877e+21   8549812   <2e-16 ***
## ASV0421     -3.648e+27  4.745e+20  -7688601   <2e-16 ***
## ASV0691     -6.872e+29  7.457e+21 -92145182   <2e-16 ***
## ASV0899      3.620e+29  8.766e+21  41293382   <2e-16 ***
## ASV1004     -1.943e+29  1.887e+22 -10297852   <2e-16 ***
## ASV1041      9.920e+29  1.932e+22  51347544   <2e-16 ***
## ASV1058     -5.604e+28  2.109e+22  -2656746   <2e-16 ***
## ASV12542    -2.944e+29  2.481e+22 -11866103   <2e-16 ***
## ASV1294      1.016e+29  4.036e+21  25168098   <2e-16 ***
## ASV13113    -3.196e+27  2.416e+20 -13225842   <2e-16 ***
## ASV1318     -4.340e+27  9.871e+20  -4397003   <2e-16 ***
## ASV2269      3.607e+30  1.764e+23  20448656   <2e-16 ***
## ASV2542     -4.161e+27  2.173e+20 -19146775   <2e-16 ***
## ASV2660      1.002e+30  3.044e+22  32932570   <2e-16 ***
## ASV2737     -1.038e+30  2.012e+22 -51601366   <2e-16 ***
## ASV2840      1.119e+29  5.483e+21  20412831   <2e-16 ***
## ASV3053      6.275e+30  2.327e+23  26961022   <2e-16 ***
## ASV3077     -5.247e+29  1.769e+22 -29659647   <2e-16 ***
## ASV3134     -6.140e+26  7.450e+19  -8241929   <2e-16 ***
## ASV3140     -1.245e+29  7.119e+21 -17487055   <2e-16 ***
## ASV3579      1.824e+28  1.133e+21  16095103   <2e-16 ***
## ASV6119             NA         NA        NA       NA    
## ASV7557             NA         NA        NA       NA    
## ASV8422             NA         NA        NA       NA    
## ASV1086             NA         NA        NA       NA    
## ASV1310     -6.441e+27  2.727e+21  -2361738   <2e-16 ***
## ASV15750     2.739e+28  1.020e+22   2685319   <2e-16 ***
## ASV16905            NA         NA        NA       NA    
## ASV2033     -1.854e+29  7.220e+21 -25674834   <2e-16 ***
## ASV2089             NA         NA        NA       NA    
## ASV2127      6.170e+28  6.107e+21  10104634   <2e-16 ***
## ASV2725      5.098e+29  1.063e+22  47959564   <2e-16 ***
## ASV2804             NA         NA        NA       NA    
## ASV3075      1.983e+28  3.872e+21   5120891   <2e-16 ***
## ASV3327     -8.463e+28  2.520e+21 -33582758   <2e-16 ***
## ASV3342      3.453e+27  1.368e+21   2523346   <2e-16 ***
## ASV3532     -3.843e+29  1.553e+22 -24744738   <2e-16 ***
## ASV3600      3.029e+27  3.781e+21    801029   <2e-16 ***
## ASV4013      8.242e+29  4.297e+22  19179508   <2e-16 ***
## ASV4136     -4.437e+29  1.005e+22 -44142967   <2e-16 ***
## ASV4195             NA         NA        NA       NA    
## ASV4407             NA         NA        NA       NA    
## ASV4717             NA         NA        NA       NA    
## ASV6794             NA         NA        NA       NA    
## ASV8324             NA         NA        NA       NA    
## ASV8981      2.590e+28  1.807e+21  14336596   <2e-16 ***
## ASV9859      1.140e+29  4.747e+21  24019076   <2e-16 ***
## ASV0936     -2.726e+28  5.069e+20 -53775218   <2e-16 ***
## ASV12683            NA         NA        NA       NA    
## ASV1293      2.111e+29  6.346e+21  33262200   <2e-16 ***
## ASV13055            NA         NA        NA       NA    
## ASV17063            NA         NA        NA       NA    
## ASV2228             NA         NA        NA       NA    
## ASV2769     -5.737e+29  3.903e+22 -14701528   <2e-16 ***
## ASV2803     -2.270e+29  2.230e+22 -10178739   <2e-16 ***
## ASV2896      5.034e+27  1.083e+20  46498426   <2e-16 ***
## ASV3062             NA         NA        NA       NA    
## ASV3107      3.218e+26  9.323e+19   3451124   <2e-16 ***
## ASV3265      2.217e+29  5.755e+21  38522384   <2e-16 ***
## ASV3666             NA         NA        NA       NA    
## ASV4497      5.080e+29  6.125e+21  82934294   <2e-16 ***
## ASV6914             NA         NA        NA       NA    
## ASV0576     -1.413e+29  3.400e+21 -41571707   <2e-16 ***
## ASV0673     -1.676e+29  1.076e+22 -15579312   <2e-16 ***
## ASV0772     -5.129e+28  1.300e+22  -3946466   <2e-16 ***
## ASV0862      8.939e+28  2.602e+22   3434799   <2e-16 ***
## ASV0898             NA         NA        NA       NA    
## ASV0910     -2.701e+28  5.924e+20 -45593216   <2e-16 ***
## ASV0964             NA         NA        NA       NA    
## ASV10059     8.888e+26  3.201e+19  27767562   <2e-16 ***
## ASV10263            NA         NA        NA       NA    
## ASV1088      5.240e+28  4.251e+21  12326886   <2e-16 ***
## ASV1101             NA         NA        NA       NA    
## ASV1183     -7.451e+27  7.724e+20  -9647179   <2e-16 ***
## ASV11956            NA         NA        NA       NA    
## ASV12774            NA         NA        NA       NA    
## ASV1321             NA         NA        NA       NA    
## ASV13793            NA         NA        NA       NA    
## ASV14482            NA         NA        NA       NA    
## ASV15483            NA         NA        NA       NA    
## ASV2062             NA         NA        NA       NA    
## ASV2132      7.987e+25  1.385e+20    576770   <2e-16 ***
## ASV2413             NA         NA        NA       NA    
## ASV2490             NA         NA        NA       NA    
## ASV2594      4.653e+27  4.638e+20  10031166   <2e-16 ***
## ASV2822             NA         NA        NA       NA    
## ASV2863             NA         NA        NA       NA    
## ASV2910             NA         NA        NA       NA    
## ASV2980      1.137e+29  2.889e+21  39374891   <2e-16 ***
## ASV3307             NA         NA        NA       NA    
## ASV3474             NA         NA        NA       NA    
## ASV3502     -1.248e+29  5.208e+21 -23965364   <2e-16 ***
## ASV4236             NA         NA        NA       NA    
## ASV4842             NA         NA        NA       NA    
## ASV4894             NA         NA        NA       NA    
## ASV5290             NA         NA        NA       NA    
## ASV5501     -4.226e+29  1.655e+22 -25534860   <2e-16 ***
## ASV5795             NA         NA        NA       NA    
## ASV5987             NA         NA        NA       NA    
## ASV6267             NA         NA        NA       NA    
## ASV6862             NA         NA        NA       NA    
## ASV7145             NA         NA        NA       NA    
## ASV7673             NA         NA        NA       NA    
## ASV7789             NA         NA        NA       NA    
## ASV7809             NA         NA        NA       NA    
## ASV8002             NA         NA        NA       NA    
## ASV8205      3.986e+27  4.371e+20   9119652   <2e-16 ***
## ASV9155             NA         NA        NA       NA    
## ASV9221      2.112e+29  7.015e+21  30108341   <2e-16 ***
## ASV9311             NA         NA        NA       NA    
## ASV9557             NA         NA        NA       NA    
## ASV9936             NA         NA        NA       NA    
## ASV1445      2.152e+28  1.898e+21  11341359   <2e-16 ***
## ASV4232      7.680e+26  2.712e+19  28320193   <2e-16 ***
## ASV6479     -1.475e+28  2.927e+20 -50387307   <2e-16 ***
## ASV0142      3.447e+29  9.967e+21  34581617   <2e-16 ***
## ASV0378      2.866e+28  6.508e+20  44044898   <2e-16 ***
## ASV1122     -6.034e+28  2.783e+21 -21676663   <2e-16 ***
## ASV0123     -1.909e+29  1.190e+22 -16040768   <2e-16 ***
## ASV2064      1.458e+29  2.785e+21  52368055   <2e-16 ***
## ASV4459     -6.508e+27  1.636e+21  -3978313   <2e-16 ***
## ASV0448      3.365e+26  7.000e+19   4806815   <2e-16 ***
## ASV0397      5.490e+27  1.784e+20  30770580   <2e-16 ***
## ASV0485      3.399e+26  4.406e+20    771529   <2e-16 ***
## ASV1566             NA         NA        NA       NA    
## ASV1365      6.724e+28  6.510e+21  10329350   <2e-16 ***
## ASV1065     -3.355e+28  7.514e+20 -44647489   <2e-16 ***
## ASV0722      1.932e+28  7.323e+20  26379161   <2e-16 ***
## ASV12660            NA         NA        NA       NA    
## ASV0223     -1.845e+27  4.095e+19 -45044973   <2e-16 ***
## ASV0229      1.037e+29  4.138e+21  25050298   <2e-16 ***
## ASV0877     -1.197e+29  2.312e+21 -51762459   <2e-16 ***
## ASV0983     -4.692e+27  1.227e+20 -38229669   <2e-16 ***
## ASV0626             NA         NA        NA       NA    
## ASV4146      1.267e+29  5.748e+21  22051982   <2e-16 ***
## ASV4175      1.468e+29  6.390e+21  22977944   <2e-16 ***
## ASV2082      4.697e+27  7.948e+21    590917   <2e-16 ***
## ASV2272      2.143e+27  1.558e+20  13759437   <2e-16 ***
## ASV2245      1.036e+28  1.416e+21   7320995   <2e-16 ***
## ASV0590             NA         NA        NA       NA    
## ASV0217     -6.082e+27  3.254e+20 -18688201   <2e-16 ***
## ASV0416     -9.352e+28  4.011e+21 -23317562   <2e-16 ***
## ASV1056      4.379e+28  9.560e+20  45806293   <2e-16 ***
## ASV7777      1.313e+26  3.125e+18  42026630   <2e-16 ***
## ASV0455     -1.599e+27  1.868e+20  -8559833   <2e-16 ***
## ASV0604             NA         NA        NA       NA    
## ASV6100     -8.892e+26  2.452e+19 -36258795   <2e-16 ***
## ASV11359            NA         NA        NA       NA    
## ASV6604     -1.357e+27  9.241e+19 -14686255   <2e-16 ***
## ASV5004     -3.297e+28  2.064e+21 -15968479   <2e-16 ***
## ASV1483      9.259e+28  5.122e+21  18078096   <2e-16 ***
## ASV9773      3.542e+24  9.017e+17   3927869   <2e-16 ***
## ASV4059      3.539e+27  1.240e+20  28534190   <2e-16 ***
## ASV1193     -1.095e+27  2.595e+19 -42211925   <2e-16 ***
## ASV4610             NA         NA        NA       NA    
## ASV0742             NA         NA        NA       NA    
## ASV1502      2.062e+28  2.101e+21   9815587   <2e-16 ***
## ASV0195     -1.136e+28  8.765e+20 -12964719   <2e-16 ***
## ASV1213     -1.282e+28  7.604e+20 -16864651   <2e-16 ***
## ASV1648     -2.280e+27  2.810e+20  -8113640   <2e-16 ***
## ASV6984     -1.247e+28  7.033e+20 -17735269   <2e-16 ***
## ASV0396      6.608e+27  3.126e+20  21138856   <2e-16 ***
## ASV4297             NA         NA        NA       NA    
## ASV2622      3.120e+27  2.408e+20  12954812   <2e-16 ***
## ASV3512      2.229e+27  2.932e+20   7604982   <2e-16 ***
## ASV2411             NA         NA        NA       NA    
## ASV2291             NA         NA        NA       NA    
## ASV0807      1.262e+28  1.128e+21  11185166   <2e-16 ***
## ASV1292      4.892e+27  7.702e+20   6352014   <2e-16 ***
## ASV1035             NA         NA        NA       NA    
## ASV0070      1.154e+26  1.873e+19   6158858   <2e-16 ***
## ASV0255     -3.377e+27  4.012e+20  -8418180   <2e-16 ***
## ASV0057     -8.343e+26  2.065e+19 -40399581   <2e-16 ***
## ASV0077      6.815e+26  4.068e+19  16755173   <2e-16 ***
## ASV0625     -3.036e+27  4.492e+20  -6758212   <2e-16 ***
## ASV2464             NA         NA        NA       NA    
## ASV1315      1.411e+29  7.399e+21  19067690   <2e-16 ***
## ASV2673     -1.360e+27  3.627e+20  -3749327   <2e-16 ***
## ASV2161     -1.153e+29  6.076e+21 -18978266   <2e-16 ***
## ASV0337      3.202e+27  3.745e+20   8551232   <2e-16 ***
## ASV7680      5.084e+27  2.001e+21   2541443   <2e-16 ***
## ASV0611      5.369e+27  3.191e+20  16822498   <2e-16 ***
## ASV3118     -9.577e+28  7.474e+21 -12812912   <2e-16 ***
## ASV1284     -1.771e+26  3.322e+19  -5330863   <2e-16 ***
## ASV0889             NA         NA        NA       NA    
## ASV4649      5.395e+27  6.636e+20   8130188   <2e-16 ***
## ASV1108      1.014e+28  4.627e+20  21915994   <2e-16 ***
## ASV0738      1.901e+27  5.845e+19  32515307   <2e-16 ***
## ASV0473     -5.865e+26  7.283e+19  -8052716   <2e-16 ***
## ASV0598             NA         NA        NA       NA    
## ASV0429      5.096e+27  1.169e+21   4358585   <2e-16 ***
## ASV1549     -3.105e+26  2.117e+19 -14663606   <2e-16 ***
## ASV1203      5.602e+27  2.656e+20  21092741   <2e-16 ***
## ASV4532     -2.086e+27  1.294e+20 -16126745   <2e-16 ***
## ASV0274     -2.665e+27  2.179e+20 -12227315   <2e-16 ***
## ASV0163      2.696e+27  1.283e+20  21009336   <2e-16 ***
## ASV1298      5.559e+27  4.606e+20  12070247   <2e-16 ***
## ASV9424     -8.099e+27  9.797e+20  -8266614   <2e-16 ***
## ASV0412     -3.417e+28  3.259e+21 -10481715   <2e-16 ***
## ASV0284      3.665e+27  2.305e+20  15901523   <2e-16 ***
## ASV0620             NA         NA        NA       NA    
## ASV0153      4.867e+27  3.860e+20  12608412   <2e-16 ***
## ASV0498     -6.103e+27  5.736e+20 -10639767   <2e-16 ***
## ASV0097      4.910e+26  4.329e+19  11343352   <2e-16 ***
## ASV0104      3.332e+27  1.657e+20  20103965   <2e-16 ***
## ASV1282      2.075e+28  1.155e+21  17960841   <2e-16 ***
## ASV3883      1.485e+28  6.012e+20  24697163   <2e-16 ***
## ASV0801      4.697e+27  3.127e+20  15019671   <2e-16 ***
## ASV1611     -5.576e+27  8.200e+20  -6800102   <2e-16 ***
## ASV0227      3.432e+27  3.254e+20  10547182   <2e-16 ***
## ASV0833             NA         NA        NA       NA    
## ASV0718      6.751e+27  5.246e+20  12869729   <2e-16 ***
## ASV1139             NA         NA        NA       NA    
## ASV0766      1.784e+28  1.552e+21  11493235   <2e-16 ***
## ASV2091     -1.802e+28  7.795e+20 -23122453   <2e-16 ***
## ASV1238      7.937e+27  2.282e+21   3478771   <2e-16 ***
## ASV9193             NA         NA        NA       NA    
## ASV0290     -1.120e+29  5.984e+21 -18720754   <2e-16 ***
## ASV0231      1.608e+27  7.642e+19  21040172   <2e-16 ***
## ASV0185      2.379e+26  1.677e+19  14185867   <2e-16 ***
## ASV2330             NA         NA        NA       NA    
## ASV3119      6.440e+26  9.435e+19   6825835   <2e-16 ***
## ASV2368      1.075e+27  1.241e+20   8662788   <2e-16 ***
## ASV0122      8.436e+26  6.313e+19  13361445   <2e-16 ***
## ASV1044     -2.838e+27  3.193e+20  -8888219   <2e-16 ***
## ASV0160     -6.269e+24  6.435e+19    -97421   <2e-16 ***
## ASV0326     -1.111e+26  1.062e+19 -10462061   <2e-16 ***
## ASV1388     -1.478e+26  1.149e+20  -1286560   <2e-16 ***
## ASV0792             NA         NA        NA       NA    
## ASV0036      3.807e+26  6.405e+19   5944935   <2e-16 ***
## ASV2125      1.250e+27  3.942e+19  31702730   <2e-16 ***
## ASV1075      2.865e+26  3.784e+19   7573138   <2e-16 ***
## ASV0390     -1.588e+26  2.865e+19  -5541211   <2e-16 ***
## ASV3790     -2.345e+27  7.708e+19 -30429042   <2e-16 ***
## ASV1535     -2.679e+26  1.155e+20  -2319101   <2e-16 ***
## ASV0263             NA         NA        NA       NA    
## ASV0675      6.067e+26  1.823e+19  33281690   <2e-16 ***
## ASV3348     -6.506e+26  6.778e+19  -9598312   <2e-16 ***
## ASV0058      3.844e+26  1.133e+19  33934764   <2e-16 ***
## ASV4142             NA         NA        NA       NA    
## ASV0059     -4.155e+25  1.098e+19  -3783418   <2e-16 ***
## ASV0013     -3.581e+25  5.209e+19   -687322   <2e-16 ***
## ASV0033     -3.528e+27  2.763e+20 -12769820   <2e-16 ***
## ASV4354             NA         NA        NA       NA    
## ASV0022      1.066e+27  7.724e+19  13798048   <2e-16 ***
## ASV0134     -3.857e+27  2.600e+20 -14833628   <2e-16 ***
## ASV0415      4.202e+26  6.435e+20    653063   <2e-16 ***
## ASV10103            NA         NA        NA       NA    
## ASV1613     -1.160e+28  8.210e+20 -14124176   <2e-16 ***
## ASV0135      5.952e+25  1.336e+19   4455140   <2e-16 ***
## ASV0469             NA         NA        NA       NA    
## ASV0471      3.040e+26  1.691e+20   1798327   <2e-16 ***
## ASV0451      1.031e+25  1.257e+19    820228   <2e-16 ***
## ASV0747     -2.304e+27  1.086e+20 -21210722   <2e-16 ***
## ASV1314      3.589e+25  8.057e+18   4455140   <2e-16 ***
## ASV0425             NA         NA        NA       NA    
## ASV0559      9.106e+26  6.336e+20   1437314   <2e-16 ***
## ASV0148     -5.587e+25  7.492e+18  -7456917   <2e-16 ***
## ASV0129      4.810e+25  3.397e+18  14161847   <2e-16 ***
## ASV1072     -1.526e+27  1.136e+20 -13434470   <2e-16 ***
## ASV2390             NA         NA        NA       NA    
## ASV0548      5.334e+26  7.540e+19   7073840   <2e-16 ***
## ASV0168     -1.521e+25  3.831e+18  -3969612   <2e-16 ***
## ASV0066     -5.903e+24  5.615e+17 -10513320   <2e-16 ***
## ASV0468     -4.286e+23  1.520e+17  -2819147   <2e-16 ***
## ASV0172      4.820e+25  9.454e+18   5098194   <2e-16 ***
## ASV0236     -1.778e+27  3.521e+19 -50495342   <2e-16 ***
## ASV0250     -3.209e+25  7.459e+18  -4302139   <2e-16 ***
## ASV0338     -2.273e+26  9.642e+19  -2357438   <2e-16 ***
## ASV0450     -2.657e+26  4.231e+19  -6280978   <2e-16 ***
## ASV0377             NA         NA        NA       NA    
## ASV1022     -3.214e+25  7.477e+18  -4298787   <2e-16 ***
## ASV6174             NA         NA        NA       NA    
## ASV0786             NA         NA        NA       NA    
## ASV0053     -8.610e+24  1.175e+19   -732625   <2e-16 ***
## ASV0697      1.543e+27  1.957e+20   7881590   <2e-16 ***
## ASV0785      2.371e+26  4.563e+19   5195032   <2e-16 ***
## ASV1967     -7.948e+25  1.431e+19  -5555794   <2e-16 ***
## ASV0385     -9.049e+26  2.859e+19 -31656179   <2e-16 ***
## ASV0295      2.494e+25  5.797e+18   4302609   <2e-16 ***
## ASV0072      2.473e+25  5.833e+18   4239359   <2e-16 ***
## ASV0157     -4.871e+25  2.318e+18 -21011084   <2e-16 ***
## ASV0501     -6.432e+27  2.152e+20 -29893804   <2e-16 ***
## ASV10729     2.606e+27  1.857e+20  14037344   <2e-16 ***
## ASV1470             NA         NA        NA       NA    
## ASV0050     -3.446e+27  2.890e+20 -11924848   <2e-16 ***
## ASV0411      1.450e+26  1.092e+19  13279190   <2e-16 ***
## ASV0549     -3.976e+26  3.550e+19 -11199578   <2e-16 ***
## ASV0184     -1.793e+24  4.024e+17  -4455140   <2e-16 ***
## ASV0705      3.550e+25  6.519e+18   5444603   <2e-16 ***
## ASV1715     -1.052e+27  5.512e+19 -19084967   <2e-16 ***
## ASV0603      5.643e+25  2.420e+19   2331574   <2e-16 ***
## ASV0826             NA         NA        NA       NA    
## ASV0034     -3.104e+25  6.968e+18  -4455140   <2e-16 ***
## ASV0838     -2.247e+27  1.824e+20 -12318957   <2e-16 ***
## ASV0614     -3.673e+25  1.228e+19  -2990984   <2e-16 ***
## ASV0014      8.634e+26  9.426e+19   9159881   <2e-16 ***
## ASV0585             NA         NA        NA       NA    
## ASV0016     -2.513e+27  1.331e+20 -18879340   <2e-16 ***
## ASV5394      1.345e+26  7.053e+19   1906834   <2e-16 ***
## ASV0666             NA         NA        NA       NA    
## ASV2085             NA         NA        NA       NA    
## ASV0003      1.294e+27  1.069e+20  12098345   <2e-16 ***
## ASV0346      7.695e+26  4.560e+19  16875761   <2e-16 ***
## ASV0267     -1.078e+27  4.833e+19 -22294991   <2e-16 ***
## ASV0353     -8.834e+24  3.682e+19   -239907   <2e-16 ***
## ASV2419      1.213e+27  2.986e+20   4062634   <2e-16 ***
## ASV0447             NA         NA        NA       NA    
## ASV0654             NA         NA        NA       NA    
## ASV0151     -1.054e+27  3.947e+19 -26711955   <2e-16 ***
## ASV0065      3.179e+25  2.107e+19   1509198   <2e-16 ***
## ASV0527     -1.562e+27  1.107e+20 -14109655   <2e-16 ***
## ASV4055             NA         NA        NA       NA    
## ASV0166             NA         NA        NA       NA    
## ASV0417     -1.310e+25  1.916e+19   -683887   <2e-16 ***
## ASV0078      7.889e+24  8.883e+17   8880320   <2e-16 ***
## ASV0322             NA         NA        NA       NA    
## ASV0156     -1.010e+26  2.738e+19  -3687845   <2e-16 ***
## ASV0648             NA         NA        NA       NA    
## ASV0407      1.663e+25  3.732e+18   4455140   <2e-16 ***
## ASV2030             NA         NA        NA       NA    
## ASV0300     -1.225e+26  1.168e+19 -10492054   <2e-16 ***
## ASV1150     -1.465e+26  8.843e+18 -16567236   <2e-16 ***
## ASV0958      1.179e+26  3.939e+19   2992785   <2e-16 ***
## ASV0216             NA         NA        NA       NA    
## ASV0446             NA         NA        NA       NA    
## ASV0367             NA         NA        NA       NA    
## ASV0200             NA         NA        NA       NA    
## ASV0334             NA         NA        NA       NA    
## ASV1311             NA         NA        NA       NA    
## ASV0458             NA         NA        NA       NA    
## ASV1371             NA         NA        NA       NA    
## ASV0418             NA         NA        NA       NA    
## ASV0004     -3.101e+25  2.914e+18 -10643188   <2e-16 ***
## ASV1943             NA         NA        NA       NA    
## ASV1495             NA         NA        NA       NA    
## ASV0901             NA         NA        NA       NA    
## ASV0628             NA         NA        NA       NA    
## ASV0400             NA         NA        NA       NA    
## ASV0116             NA         NA        NA       NA    
## ASV0788             NA         NA        NA       NA    
## ASV0117     -2.375e+24  2.151e+17 -11039688   <2e-16 ***
## ASV3137             NA         NA        NA       NA    
## ASV0001             NA         NA        NA       NA    
## ASV1651             NA         NA        NA       NA    
## ASV1692             NA         NA        NA       NA    
## ASV0660             NA         NA        NA       NA    
## ASV0508             NA         NA        NA       NA    
## ASV1660             NA         NA        NA       NA    
## ASV0233             NA         NA        NA       NA    
## ASV1343             NA         NA        NA       NA    
## ASV0209             NA         NA        NA       NA    
## ASV0193             NA         NA        NA       NA    
## ASV0357             NA         NA        NA       NA    
## ASV0198             NA         NA        NA       NA    
## ASV0007             NA         NA        NA       NA    
## ASV1772             NA         NA        NA       NA    
## ASV0009             NA         NA        NA       NA    
## ASV0006             NA         NA        NA       NA    
## ASV0011             NA         NA        NA       NA    
## ASV0015             NA         NA        NA       NA    
## ASV0017             NA         NA        NA       NA    
## ASV0235             NA         NA        NA       NA    
## ASV0382             NA         NA        NA       NA    
## ASV2357             NA         NA        NA       NA    
## ASV0567      9.283e+25  3.757e+19   2470964   <2e-16 ***
## ASV0165             NA         NA        NA       NA    
## ASV0005             NA         NA        NA       NA    
## ASV0384             NA         NA        NA       NA    
## ASV0002             NA         NA        NA       NA    
## ASV3017             NA         NA        NA       NA    
## ASV0091             NA         NA        NA       NA    
## ASV0186             NA         NA        NA       NA    
## ASV0370             NA         NA        NA       NA    
## ASV0018             NA         NA        NA       NA    
## ASV1377             NA         NA        NA       NA    
## ASV0019             NA         NA        NA       NA    
## ASV0023             NA         NA        NA       NA    
## ASV2194             NA         NA        NA       NA    
## ASV1155             NA         NA        NA       NA    
## ASV0510             NA         NA        NA       NA    
## ASV2371             NA         NA        NA       NA    
## ASV0024             NA         NA        NA       NA    
## ASV2452             NA         NA        NA       NA    
## ASV2332             NA         NA        NA       NA    
## ASV2591             NA         NA        NA       NA    
## ASV0521             NA         NA        NA       NA    
## ASV5542             NA         NA        NA       NA    
## ASV0336             NA         NA        NA       NA    
## ASV10102            NA         NA        NA       NA    
## ASV16823            NA         NA        NA       NA    
## ASV3104             NA         NA        NA       NA    
## ASV0781             NA         NA        NA       NA    
## ASV10899            NA         NA        NA       NA    
## ASV11222            NA         NA        NA       NA    
## ASV11327            NA         NA        NA       NA    
## ASV12458            NA         NA        NA       NA    
## ASV1636             NA         NA        NA       NA    
## ASV1890             NA         NA        NA       NA    
## ASV2898             NA         NA        NA       NA    
## ASV8328             NA         NA        NA       NA    
## ASV0709             NA         NA        NA       NA    
## ASV0856             NA         NA        NA       NA    
## ASV0909             NA         NA        NA       NA    
## ASV0937             NA         NA        NA       NA    
## ASV11390            NA         NA        NA       NA    
## ASV11966            NA         NA        NA       NA    
## ASV12990            NA         NA        NA       NA    
## ASV14797            NA         NA        NA       NA    
## ASV14904            NA         NA        NA       NA    
## ASV15304            NA         NA        NA       NA    
## ASV16696            NA         NA        NA       NA    
## ASV1690             NA         NA        NA       NA    
## ASV2029             NA         NA        NA       NA    
## ASV2834             NA         NA        NA       NA    
## ASV4003             NA         NA        NA       NA    
## ASV4064             NA         NA        NA       NA    
## ASV4294             NA         NA        NA       NA    
## ASV4609             NA         NA        NA       NA    
## ASV6283             NA         NA        NA       NA    
## ASV6491             NA         NA        NA       NA    
## ASV7453             NA         NA        NA       NA    
## ASV7959             NA         NA        NA       NA    
## ASV8219             NA         NA        NA       NA    
## ASV8547             NA         NA        NA       NA    
## ASV9319             NA         NA        NA       NA    
## ASV9382             NA         NA        NA       NA    
## ASV11516            NA         NA        NA       NA    
## ASV14377            NA         NA        NA       NA    
## ASV1867             NA         NA        NA       NA    
## ASV1895             NA         NA        NA       NA    
## ASV3168             NA         NA        NA       NA    
## ASV4449             NA         NA        NA       NA    
## ASV6596             NA         NA        NA       NA    
## ASV7492             NA         NA        NA       NA    
## ASV9854             NA         NA        NA       NA    
## ASV6296             NA         NA        NA       NA    
## ASV4201             NA         NA        NA       NA    
## ASV0552             NA         NA        NA       NA    
## ASV3671             NA         NA        NA       NA    
## ASV3529             NA         NA        NA       NA    
## ASV1060             NA         NA        NA       NA    
## ASV0239             NA         NA        NA       NA    
## ASV5711             NA         NA        NA       NA    
## ASV4152             NA         NA        NA       NA    
## ASV1461             NA         NA        NA       NA    
## ASV2877             NA         NA        NA       NA    
## ASV0012             NA         NA        NA       NA    
## ASV9823             NA         NA        NA       NA    
## ASV0008             NA         NA        NA       NA    
## ASV7832             NA         NA        NA       NA    
## ASV1915             NA         NA        NA       NA    
## ASV0055             NA         NA        NA       NA    
## ASV0032             NA         NA        NA       NA    
## ASV2977             NA         NA        NA       NA    
## ASV0466             NA         NA        NA       NA    
## ASV3866             NA         NA        NA       NA    
## ASV0040             NA         NA        NA       NA    
## ASV0496             NA         NA        NA       NA    
## ASV0052             NA         NA        NA       NA    
## ASV3828             NA         NA        NA       NA    
## ASV1930             NA         NA        NA       NA    
## ASV2126             NA         NA        NA       NA    
## ASV0793             NA         NA        NA       NA    
## ASV0299             NA         NA        NA       NA    
## ASV0208             NA         NA        NA       NA    
## ASV0511             NA         NA        NA       NA    
## ASV1123             NA         NA        NA       NA    
## ASV0099             NA         NA        NA       NA    
## ASV0752             NA         NA        NA       NA    
## ASV0883             NA         NA        NA       NA    
## ASV0683     -1.500e+28  1.058e+21 -14169982   <2e-16 ***
## ASV4117             NA         NA        NA       NA    
## ASV2172             NA         NA        NA       NA    
## ASV0330             NA         NA        NA       NA    
## ASV0728             NA         NA        NA       NA    
## ASV0499             NA         NA        NA       NA    
## ASV0120             NA         NA        NA       NA    
## ASV1446             NA         NA        NA       NA    
## ASV17171            NA         NA        NA       NA    
## ASV0533             NA         NA        NA       NA    
## ASV2495             NA         NA        NA       NA    
## ASV5582             NA         NA        NA       NA    
## ASV1488             NA         NA        NA       NA    
## ASV0682             NA         NA        NA       NA    
## ASV0068             NA         NA        NA       NA    
## ASV1987             NA         NA        NA       NA    
## ASV0035             NA         NA        NA       NA    
## ASV7192             NA         NA        NA       NA    
## ASV0873             NA         NA        NA       NA    
## ASV4749             NA         NA        NA       NA    
## ASV2174             NA         NA        NA       NA    
## ASV1476             NA         NA        NA       NA    
## ASV0740             NA         NA        NA       NA    
## ASV0170             NA         NA        NA       NA    
## ASV2466             NA         NA        NA       NA    
## ASV1709             NA         NA        NA       NA    
## ASV6170             NA         NA        NA       NA    
## ASV3673             NA         NA        NA       NA    
## ASV1745             NA         NA        NA       NA    
## ---
## Signif. codes:  0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1
## 
## (Dispersion parameter for binomial family taken to be 1)
## 
##     Null deviance:  385.39  on 277  degrees of freedom
## Residual deviance: 3171.84  on  46  degrees of freedom
## AIC: 3635.8
## 
## Number of Fisher Scoring iterations: 11
  • The p-values above are all the same which is not good.

From PCA of Clade C, there were about 150 or so ASVs that contributed the most in Dimension 1

bind_cols(lr_data[,1:2], 
lr_data[3:152] %>% clr() # sample id and Clade
) -> lr_clr_150

logreg_150 <- stats::glm(as.factor(Clade) ~ . ,
                          data = lr_clr_150[,-1],
                          family = "binomial")
summary(logreg_150)
## 
## Call:
## stats::glm(formula = as.factor(Clade) ~ ., family = "binomial", 
##     data = lr_clr_150[, -1])
## 
## Coefficients: (71 not defined because of singularities)
##               Estimate Std. Error   z value Pr(>|z|)    
## (Intercept)  2.149e+14  4.856e+06  44249740   <2e-16 ***
## ASV1236      6.118e+18  7.124e+10  85883777   <2e-16 ***
## ASV0421     -5.197e+17  8.905e+09 -58360413   <2e-16 ***
## ASV0691      3.128e+26  2.109e+19  14829839   <2e-16 ***
## ASV0899     -5.618e+26  3.788e+19 -14829839   <2e-16 ***
## ASV1004      3.720e+19  4.870e+11  76384245   <2e-16 ***
## ASV1041      4.433e+26  2.989e+19  14829839   <2e-16 ***
## ASV1058      2.926e+19  4.996e+11  58560540   <2e-16 ***
## ASV12542    -5.350e+27  3.607e+20 -14829840   <2e-16 ***
## ASV1294      3.695e+25  2.492e+18  14829840   <2e-16 ***
## ASV13113     4.072e+29  2.746e+22  14829839   <2e-16 ***
## ASV1318      2.966e+17  5.998e+09  49443492   <2e-16 ***
## ASV2269             NA         NA        NA       NA    
## ASV2542      4.543e+25  3.063e+18  14829838   <2e-16 ***
## ASV2660     -3.446e+27  2.323e+20 -14829840   <2e-16 ***
## ASV2737     -9.245e+25  6.234e+18 -14829840   <2e-16 ***
## ASV2840      4.183e+25  2.821e+18  14829837   <2e-16 ***
## ASV3053      1.633e+29  1.101e+22  14829839   <2e-16 ***
## ASV3077     -2.155e+28  1.453e+21 -14829839   <2e-16 ***
## ASV3134     -1.293e+17  1.615e+09 -80082376   <2e-16 ***
## ASV3140      2.298e+19  2.657e+11  86471491   <2e-16 ***
## ASV3579     -2.267e+16  2.802e+08 -80875064   <2e-16 ***
## ASV6119             NA         NA        NA       NA    
## ASV7557             NA         NA        NA       NA    
## ASV8422             NA         NA        NA       NA    
## ASV1086             NA         NA        NA       NA    
## ASV1310     -3.400e+25  2.293e+18 -14829839   <2e-16 ***
## ASV15750     1.484e+25  1.001e+18  14829851   <2e-16 ***
## ASV16905            NA         NA        NA       NA    
## ASV2033      4.483e+18  1.678e+11  26716873   <2e-16 ***
## ASV2089             NA         NA        NA       NA    
## ASV2127     -2.913e+16  2.876e+09 -10126318   <2e-16 ***
## ASV2725     -1.048e+24  7.064e+16 -14830125   <2e-16 ***
## ASV2804             NA         NA        NA       NA    
## ASV3075     -2.235e+16  2.934e+08 -76164934   <2e-16 ***
## ASV3327      1.397e+17  1.083e+10  12902533   <2e-16 ***
## ASV3342     -1.152e+17  4.288e+09 -26878757   <2e-16 ***
## ASV3532      1.568e+18  5.906e+10  26551172   <2e-16 ***
## ASV3600      1.219e+19  1.767e+11  69017494   <2e-16 ***
## ASV4013      5.762e+27  3.886e+20  14829839   <2e-16 ***
## ASV4136      5.761e+26  3.885e+19  14829840   <2e-16 ***
## ASV4195             NA         NA        NA       NA    
## ASV4407             NA         NA        NA       NA    
## ASV4717             NA         NA        NA       NA    
## ASV6794             NA         NA        NA       NA    
## ASV8324             NA         NA        NA       NA    
## ASV8981     -8.208e+16  2.908e+09 -28224447   <2e-16 ***
## ASV9859      7.510e+16  8.436e+08  89022102   <2e-16 ***
## ASV0936      2.117e+18  3.575e+10  59221098   <2e-16 ***
## ASV12683            NA         NA        NA       NA    
## ASV1293      2.871e+17  2.460e+10  11670920   <2e-16 ***
## ASV13055            NA         NA        NA       NA    
## ASV17063            NA         NA        NA       NA    
## ASV2228             NA         NA        NA       NA    
## ASV2769     -3.292e+27  2.220e+20 -14829839   <2e-16 ***
## ASV2803     -1.347e+27  9.085e+19 -14829840   <2e-16 ***
## ASV2896     -6.332e+16  1.848e+09 -34256411   <2e-16 ***
## ASV3062             NA         NA        NA       NA    
## ASV3107             NA         NA        NA       NA    
## ASV3265      7.403e+17  5.337e+10  13870427   <2e-16 ***
## ASV3666             NA         NA        NA       NA    
## ASV4497     -9.852e+25  6.643e+18 -14829840   <2e-16 ***
## ASV6914             NA         NA        NA       NA    
## ASV0576      4.451e+17  2.088e+10  21314782   <2e-16 ***
## ASV0673     -1.804e+25  1.216e+18 -14829838   <2e-16 ***
## ASV0772     -7.998e+18  1.251e+11 -63943266   <2e-16 ***
## ASV0862             NA         NA        NA       NA    
## ASV0898             NA         NA        NA       NA    
## ASV0910      1.612e+17  1.272e+10  12671632   <2e-16 ***
## ASV0964             NA         NA        NA       NA    
## ASV10059            NA         NA        NA       NA    
## ASV10263            NA         NA        NA       NA    
## ASV1088      6.437e+16  2.268e+09  28384567   <2e-16 ***
## ASV1101             NA         NA        NA       NA    
## ASV1183             NA         NA        NA       NA    
## ASV11956            NA         NA        NA       NA    
## ASV12774            NA         NA        NA       NA    
## ASV1321             NA         NA        NA       NA    
## ASV13793            NA         NA        NA       NA    
## ASV14482            NA         NA        NA       NA    
## ASV15483            NA         NA        NA       NA    
## ASV2062             NA         NA        NA       NA    
## ASV2132      4.399e+17  6.526e+09  67396431   <2e-16 ***
## ASV2413             NA         NA        NA       NA    
## ASV2490             NA         NA        NA       NA    
## ASV2594      4.337e+14  3.793e+08   1143536   <2e-16 ***
## ASV2822             NA         NA        NA       NA    
## ASV2863             NA         NA        NA       NA    
## ASV2910             NA         NA        NA       NA    
## ASV2980      7.972e+17  1.282e+10  62199372   <2e-16 ***
## ASV3307             NA         NA        NA       NA    
## ASV3474      5.509e+25  3.715e+18  14829838   <2e-16 ***
## ASV3502      3.731e+16  6.477e+08  57610407   <2e-16 ***
## ASV4236             NA         NA        NA       NA    
## ASV4842             NA         NA        NA       NA    
## ASV4894             NA         NA        NA       NA    
## ASV5290             NA         NA        NA       NA    
## ASV5501     -6.408e+16  2.030e+09 -31561118   <2e-16 ***
## ASV5795             NA         NA        NA       NA    
## ASV5987             NA         NA        NA       NA    
## ASV6267             NA         NA        NA       NA    
## ASV6862             NA         NA        NA       NA    
## ASV7145             NA         NA        NA       NA    
## ASV7673             NA         NA        NA       NA    
## ASV7789             NA         NA        NA       NA    
## ASV7809             NA         NA        NA       NA    
## ASV8002             NA         NA        NA       NA    
## ASV8205             NA         NA        NA       NA    
## ASV9155             NA         NA        NA       NA    
## ASV9221     -4.422e+16  2.062e+09 -21450288   <2e-16 ***
## ASV9311             NA         NA        NA       NA    
## ASV9557             NA         NA        NA       NA    
## ASV9936             NA         NA        NA       NA    
## ASV1445     -5.879e+16  1.853e+09 -31719605   <2e-16 ***
## ASV4232             NA         NA        NA       NA    
## ASV6479             NA         NA        NA       NA    
## ASV0142      1.171e+18  7.597e+10  15416523   <2e-16 ***
## ASV0378     -1.798e+17  3.179e+09 -56558628   <2e-16 ***
## ASV1122      1.142e+18  1.348e+10  84701298   <2e-16 ***
## ASV0123     -6.152e+17  3.339e+10 -18424047   <2e-16 ***
## ASV2064     -6.218e+16  1.981e+09 -31388944   <2e-16 ***
## ASV4459     -1.190e+17  1.638e+09 -72644566   <2e-16 ***
## ASV0448     -1.637e+16  2.242e+08 -72998113   <2e-16 ***
## ASV0397     -9.218e+16  1.841e+09 -50077201   <2e-16 ***
## ASV0485     -9.927e+16  1.661e+09 -59770485   <2e-16 ***
## ASV1566             NA         NA        NA       NA    
## ASV1365      1.641e+17  4.070e+09  40312359   <2e-16 ***
## ASV1065             NA         NA        NA       NA    
## ASV0722     -6.746e+16  1.952e+09 -34555746   <2e-16 ***
## ASV12660            NA         NA        NA       NA    
## ASV0223     -6.922e+16  1.846e+09 -37489978   <2e-16 ***
## ASV0229     -5.924e+16  2.029e+09 -29189953   <2e-16 ***
## ASV0877     -5.465e+16  1.986e+09 -27517061   <2e-16 ***
## ASV0983     -7.937e+16  1.838e+09 -43184389   <2e-16 ***
## ASV0626             NA         NA        NA       NA    
## ASV4146     -6.832e+17  2.641e+10 -25872713   <2e-16 ***
## ASV4175     -5.768e+16  2.039e+09 -28294358   <2e-16 ***
## ASV2082     -7.444e+16  1.919e+09 -38799312   <2e-16 ***
## ASV2272     -1.178e+17  1.622e+09 -72663987   <2e-16 ***
## ASV2245     -4.873e+15  3.110e+09  -1566877   <2e-16 ***
## ASV0590             NA         NA        NA       NA    
## ASV0217     -5.831e+16  1.980e+09 -29444555   <2e-16 ***
## ASV0416     -6.619e+16  2.113e+09 -31330716   <2e-16 ***
## ASV1056      2.280e+17  1.630e+10  13986988   <2e-16 ***
## ASV7777             NA         NA        NA       NA    
## ASV0455     -7.155e+16  1.959e+09 -36529190   <2e-16 ***
## ASV0604             NA         NA        NA       NA    
## ASV6100             NA         NA        NA       NA    
## ASV11359            NA         NA        NA       NA    
## ASV6604     -3.107e+15  4.398e+07 -70641463   <2e-16 ***
## ASV5004             NA         NA        NA       NA    
## ---
## Signif. codes:  0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1
## 
## (Dispersion parameter for binomial family taken to be 1)
## 
##     Null deviance:  385.39  on 277  degrees of freedom
## Residual deviance: 5911.16  on 198  degrees of freedom
## AIC: 6071.2
## 
## Number of Fisher Scoring iterations: 23

  • For these data, it is not possible to get a decent logistic regression model even when reducing the ASV columns to the minimum from PCA analysis.

  • The goal was to try and estimate or explain which ASVs might present the most impact for Clade C, but thes data from the t–SNE plot above and subsequent logistic modeling attempts do not produce a good model.

  • Please see the RandomForest.Rmd file for non-linear modeling.